# VirDep 🧬

**Identify host dependency factors for viruses using omics data and network biology.**

VirDep is a Python toolkit for bioinformaticians and virologists that enables the discovery of host genes and pathways critical to viral infection and replication. It integrates CRISPR screen data, transcriptomics, and protein interaction networks to prioritize host dependency factors.

---

## 🔍 Features

- Analyze CRISPR/Cas9 screen or RNAi data
- Integrate transcriptomic data (bulk or single-cell)
- Network-based prioritization of host factors
- Visualize virus-host interaction maps
- Custom model support (e.g. random forest, logistic regression)

---

## 📦 Installation

```bash
pip install virdep
```

Or install from source:

```bash
git clone https://github.com/yourusername/virdep.git
cd virdep
pip install -e .
```

## 🧠 Use Cases

- Host factor identification for viruses (e.g. SARS-CoV-2, HIV, Influenza)
- Functional genomics analysis using CRISPR or RNAi screens
- Integration of transcriptomic data with known host-virus interactions
- Hypothesis generation for experimental virology

## 🔍 Features

- Analyze CRISPR/Cas9 or RNAi screen data
- Integrate transcriptomic or proteomic datasets
- Network-based ranking of host dependency genes
  .
- coming soon...
- ..
