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Methodology
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Time-Aware PC Algorithm
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TPC estimates the Causal Functional Connectivity (CFC) from time series observations. :cite:`biswasshlizerman2022-2,biswasshlizerman2022-1`.

.. image:: TPC_Schematic.png
   :align: center
   :width: 500

PC Algorithm
------------

PC is an algorithm for causal inference based on Directed Probabilistic Graphical Modeling (DPGM), which is suited for static data, i.e., independent and identically distributed observations. :cite:`kalishbuhlmann,biswasshlizerman2022-1`.

.. .. image:: PC_Schematic.png
..    :align: center
..    :width: 500


Granger Causality
-----------------

Granger causality (GC) is a statistical methodology for determining whether one time series is useful in predicting another :cite:`granger1969investigating,biswasshlizerman2022-1`.

Comparison of Methodologies
---------------------------

The following summary compares over multiple criteria and shows the advantages of TPC.

.. image:: tablesummary.png
   :align: center
   :width: 500