#Gene_accession	TypeGene	Mutation ID	Codon_pos	Ref_nuc	Ref_codon	Res_codon	Class	Phenotype	PMID	Mechanism of resistance	Notes	Required mutation	% abundance mutation required
gyrA_1_CP045012.1	AA	SER-83	83	AGT	S	R,I,N,L,Y	Quinolone	Nalidixic acid, Ciprofloxacin	12373497,9527801	Target modification	Phenotype described only in association with parC mutations, unknown phenotype if the present mutation occurs alone		
gyrA_1_CP045012.1	AA	GLU-87	87	GAG	E	K,G,L	Quinolone	Nalidixic acid, Ciprofloxacin	12373497,12373497,12373497	Target modification	Phenotype described only in association with parC mutations, unknown phenotype if the present mutation occurs alone		
gyrA_1_CP045012.1	AA	SER-97	97	AGT	S	N	Quinolone	Nalidixic acid, Ciprofloxacin	10508034	Target modification	Phenotype described only in association with parC mutations, unknown phenotype if the present mutation occurs alone		
parC_1_LR536658.1	AA	SER-80	80	AGC	S	R,I	Quinolone	Nalidixic acid, Ciprofloxacin	12373497,12373497	Target modification			
parC_1_LR536658.1	AA	GLU-84	84	GAA	E	A,K,T	Quinolone	Nalidixic acid, Ciprofloxacin	12373497,9527801	Target modification			
pbp5_1_AAK43724.1	AA	VAL-24	24	GTA	V	A	Beta-lactam	Ampicillin	25182648	Target modification	The nineteen pbp5 mutations must be present simultaneously for resistance phenotype		
pbp5_1_AAK43724.1	AA	SER-27	27	AGT	S	G	Beta-lactam	Ampicillin	25182648	Target modification	The nineteen pbp5 mutations must be present simultaneously for resistance phenotype		
pbp5_1_AAK43724.1	AA	ARG-34	34	CGG	R	Q	Beta-lactam	Ampicillin	25182648	Target modification	The nineteen pbp5 mutations must be present simultaneously for resistance phenotype		
pbp5_1_AAK43724.1	AA	GLY-66	66	GGA	G	E	Beta-lactam	Ampicillin	25182648	Target modification	The nineteen pbp5 mutations must be present simultaneously for resistance phenotype		
pbp5_1_AAK43724.1	AA	ALA-68	68	GCA	A	T	Beta-lactam	Ampicillin	25182648	Target modification	The nineteen pbp5 mutations must be present simultaneously for resistance phenotype		
pbp5_1_AAK43724.1	AA	GLU-85	85	GAA	E	D	Beta-lactam	Ampicillin	25182648	Target modification	The nineteen pbp5 mutations must be present simultaneously for resistance phenotype		
pbp5_1_AAK43724.1	AA	GLU-100	100	GAG	E	Q	Beta-lactam	Ampicillin	25182648	Target modification	The nineteen pbp5 mutations must be present simultaneously for resistance phenotype		
pbp5_1_AAK43724.1	AA	LYS-144	144	AAA	K	Q	Beta-lactam	Ampicillin	25182648	Target modification	The nineteen pbp5 mutations must be present simultaneously for resistance phenotype		
pbp5_1_AAK43724.1	AA	THR-172	172	ACA	T	A	Beta-lactam	Ampicillin	25182648	Target modification	The nineteen pbp5 mutations must be present simultaneously for resistance phenotype		
pbp5_1_AAK43724.1	AA	LEU-177	177	TTA	L	I	Beta-lactam	Ampicillin	25182648	Target modification	The nineteen pbp5 mutations must be present simultaneously for resistance phenotype		
pbp5_1_AAK43724.1	AA	ASP-204	204	GAC	D	G	Beta-lactam	Ampicillin	25182648	Target modification	The nineteen pbp5 mutations must be present simultaneously for resistance phenotype		
pbp5_1_AAK43724.1	AA	ALA-216	216	GCA	A	S	Beta-lactam	Ampicillin	25182648	Target modification	The nineteen pbp5 mutations must be present simultaneously for resistance phenotype		
pbp5_1_AAK43724.1	AA	THR-324	324	ACA	T	A	Beta-lactam	Ampicillin	25182648	Target modification	The nineteen pbp5 mutations must be present simultaneously for resistance phenotype		
pbp5_1_AAK43724.1	AA	MET-485	485	ATG	M	A,T	Beta-lactam	Ampicillin	25182648,25182648	Target modification	The nineteen pbp5 mutations must be present simultaneously for resistance phenotype		
pbp5_1_AAK43724.1	AA	ASN-496	496	AAT	N	K	Beta-lactam	Ampicillin	25182648	Target modification	The nineteen pbp5 mutations must be present simultaneously for resistance phenotype		
pbp5_1_AAK43724.1	AA	ALA-499	499	GCA	A	T,I	Beta-lactam	Ampicillin	25182648,25182648	Target modification	The nineteen pbp5 mutations must be present simultaneously for resistance phenotype		
pbp5_1_AAK43724.1	AA	GLU-525	525	GAG	E	D	Beta-lactam	Ampicillin	25182648	Target modification	The nineteen pbp5 mutations must be present simultaneously for resistance phenotype		
pbp5_1_AAK43724.1	AA	VAL-586	586	GTA	V	L	Beta-lactam	Ampicillin	25182648	Target modification	Not essential for resistance phenotype		
pbp5_1_AAK43724.1	AA	GLU-629	629	GAA	E	V	Beta-lactam	Ampicillin	25182648	Target modification	The nineteen pbp5 mutations must be present simultaneously for resistance phenotype		
pbp5_1_AAK43724.1	AA	PRO-667	667	CCC	P	S	Beta-lactam	Ampicillin	25182648	Target modification	The nineteen pbp5 mutations must be present simultaneously for resistance phenotype		
# Indels													
#pbp5_1_AAK43724.1	AA		466	-	ins	S,D	Beta-lactam	Ampicillin	25182648,25182648	Target modification	Not essential for resistance phenotype		
pbp5_1_AAK43724.1	NUC		1396	-	ins	TCT,TCC,TCA,TCG,AGT,AGC,GAT,GAC	Beta-lactam	Ampicillin	25182648,25182648	Target modification	Not essential for resistance phenotype