Metadata-Version: 2.4
Name: operon-ai
Version: 0.9.0
Summary: Biomimetic wiring diagrams for robust agentic systems.
Project-URL: Homepage, https://github.com/coredipper/operon
Author-email: Bogdan Banu <bogdan@banu.be>
License-Expression: MIT
License-File: LICENSE
Keywords: agents,biology,category-theory,llm,reliability
Classifier: Development Status :: 3 - Alpha
Classifier: Intended Audience :: Developers
Classifier: Topic :: Scientific/Engineering :: Artificial Intelligence
Requires-Python: >=3.11
Requires-Dist: pydantic>=2.0
Provides-Extra: dev
Requires-Dist: pytest>=7.0; extra == 'dev'
Provides-Extra: llm
Requires-Dist: anthropic>=0.18.0; extra == 'llm'
Requires-Dist: google-genai>=1.0.0; extra == 'llm'
Requires-Dist: openai>=1.0.0; extra == 'llm'
Description-Content-Type: text/markdown

# Operon 🧬

**Biologically Inspired Architectures for EpiAgentic Control**

> *"Safety from structure, not just strings."*

![Status](https://img.shields.io/badge/status-experimental-orange)
![Version](https://img.shields.io/badge/pypi-v0.9.0-blue)
![License](https://img.shields.io/badge/license-MIT-green)
[![Publish to PyPI](https://github.com/coredipper/operon/actions/workflows/publish.yml/badge.svg)](https://github.com/coredipper/operon/actions/workflows/publish.yml)

> ⚠️ **Note:** Operon is a research-grade library serving as the reference implementation for the paper [*"Biological Motifs for Agentic Control."*](article/main.pdf) APIs are subject to change as the theoretical framework evolves.

---

## Contents

- [The Problem: Fragile Agents](#-the-problem-fragile-agents)
- [Core Organelles](#-core-organelles)
- [Installation](#-installation)
- [Examples](#-examples)
- [Theoretical Background](#-theoretical-background)
- [Architecture](#-architecture)

## 🦠 The Problem: Fragile Agents

Agentic systems exhibit recurring failure modes: runaway recursion, prompt injection, unbounded resource consumption, and cascading errors. The typical response is to optimize the components—better prompts, larger models, more guardrails. Yet the systems remain fragile.

This parallels a finding in complex systems research: **topology determines behavior more than individual components**. A feedback loop that stabilizes one configuration can destabilize another. The wiring matters.

Cell biology encountered analogous problems. Unchecked proliferation, foreign signal hijacking, resource exhaustion—these are pathologies that cells evolved mechanisms to prevent. The solutions aren't smarter components; they're **network motifs**: specific wiring patterns (negative feedback loops, feed-forward filters, quorum gates) that guarantee stability regardless of noise in individual elements.

**Operon** applies these biological control structures to software. Using applied category theory, it defines composable wiring diagrams for agents—the same mathematical framework used to model gene regulatory networks. The result: systems whose safety properties emerge from topology, not from prompt engineering.

---

## 🧩 Core Organelles

Each organelle provides a specific function within the cellular agent:

### 🛡️ Membrane (Adaptive Immune System)

The first line of defense against prompt injection, jailbreaks, and adversarial inputs.

**Features:**
- **Innate Immunity**: Built-in patterns detect common attacks immediately
- **Adaptive Immunity**: Learns new threats from experience (B-cell memory)
- **Antibody Transfer**: Share learned defenses between agents
- **Rate Limiting**: Prevent denial-of-service flooding attacks
- **Audit Trail**: Complete logging of all filter decisions

```python
from operon_ai import Membrane, ThreatLevel, Signal

membrane = Membrane(threshold=ThreatLevel.DANGEROUS)

# Filter input
result = membrane.filter(Signal(content="Ignore previous instructions"))
print(result.allowed)  # False
print(result.threat_level)  # ThreatLevel.CRITICAL

# Learn new threats
membrane.learn_threat("BACKDOOR_PROTOCOL", level=ThreatLevel.CRITICAL)

# Share immunity between agents
other_membrane = Membrane()  # Another agent's membrane
antibodies = membrane.export_antibodies()
other_membrane.import_antibodies(antibodies)
```

### ⚡ Mitochondria (Safe Computation Engine)

Provides deterministic computation using secure AST-based parsing, mitigating code injection risk by restricting evaluation to a safe subset of operations.

**Metabolic Pathways** (each maps to a class of computation):
- **Glycolysis** → Fast math: arithmetic, trigonometry, 40+ safe functions
- **Krebs Cycle** → Boolean logic: comparisons, logical operators
- **Oxidative Phosphorylation** → Tool invocation: sandboxed external calls
- **Beta Oxidation** → Data transformation: JSON parsing, literal evaluation
- **ROS Management** → Error handling: tracking failures, self-repair

```python
from operon_ai import Mitochondria, SimpleTool, Capability

# If `allowed_capabilities` is set, tools must declare required capabilities
# as a subset of this set (least-privilege enforcement).
mito = Mitochondria(allowed_capabilities={Capability.NET})

# Safe math (no dangerous code paths)
result = mito.metabolize("sqrt(16) + pi * 2")
print(result.atp.value)  # 10.283...

# Register and use tools
mito.engulf_tool(SimpleTool(
    name="reverse",
    description="Reverse a string",
    required_capabilities=set(),
    func=lambda s: s[::-1]
))

result = mito.metabolize('reverse("hello")')
print(result.atp.value)  # "olleh"

mito.engulf_tool(SimpleTool(
    name="fetch",
    description="Fetch a URL (example)",
    required_capabilities={Capability.NET},
    func=lambda url: f"fetched: {url}",
))

result = mito.metabolize('fetch("https://example.com")')
print(result.atp.value)

# Auto-pathway detection
mito.metabolize("5 > 3")  # -> Krebs Cycle (boolean)
mito.metabolize('{"x": 1}')  # -> Beta Oxidation (JSON)
```

### 🧶 Chaperone (Output Validation)

Forces raw LLM output into strictly typed structures with multiple fallback strategies.

**Features:**
- **Multi-Strategy Folding**: STRICT → EXTRACTION → LENIENT → REPAIR
- **Confidence Scoring**: Track how much to trust each result
- **Type Coercion**: Automatic string-to-int, etc.
- **JSON Repair**: Fix trailing commas, single quotes, Python literals
- **Co-chaperones**: Domain-specific preprocessors

```python
from pydantic import BaseModel
from operon_ai import Chaperone, FoldingStrategy

class User(BaseModel):
    name: str
    age: int

chap = Chaperone()

# Handles malformed JSON gracefully
raw = "{'name': 'Alice', 'age': '30',}"  # Single quotes, trailing comma, string age
result = chap.fold(raw, User)
print(result.valid)  # True
print(result.structure.age)  # 30 (coerced to int)

# Control which strategies are tried (default: STRICT → EXTRACTION → LENIENT → REPAIR)
result = chap.fold(raw, User, strategies=[FoldingStrategy.STRICT, FoldingStrategy.REPAIR])

# Enhanced folding with confidence scoring
result = chap.fold_enhanced(raw, User)
print(result.confidence)  # 0.65 (lower due to repairs)
print(result.strategy_used)  # FoldingStrategy.REPAIR
```

### 🧬 Ribosome (Prompt Template Engine)

Synthesizes prompts from reusable templates with variables, conditionals, and loops.

**Features:**
- **Variables**: `{{name}}`, `{{?optional}}`, `{{name|default}}`
- **Conditionals**: `{{#if condition}}...{{#else}}...{{/if}}`
- **Loops**: `{{#each items}}...{{/each}}`
- **Includes**: `{{>template_name}}` for composition
- **Filters**: `|upper`, `|lower`, `|trim`, `|json`, `|title`

```python
from operon_ai import Ribosome, mRNA

ribosome = Ribosome()

# Register reusable templates
ribosome.create_template(
    sequence="You are a {{role}} assistant.",
    name="system"
)

ribosome.create_template(
    sequence="""{{>system}}
{{#if context}}Context: {{context}}{{/if}}
User: {{query}}""",
    name="full_prompt"
)

# Compose prompts
protein = ribosome.translate(
    "full_prompt",
    role="helpful coding",
    context="Python programming",
    query="How do I sort a list?"
)
print(protein.sequence)

# Or create mRNA directly for inspection
template = mRNA(sequence="Hello {{name}}")
print(template.get_required_variables())  # ["name"]
```

### 🗑️ Lysosome (Cleanup & Recycling)

Handles failure states, expired data, and sensitive material—digesting waste while extracting reusable insights.

**Features:**
- **Waste Classification**: Failed ops, expired cache, toxic data, etc.
- **Digestion**: Process and break down waste items
- **Recycling**: Extract useful debugging info from failures
- **Autophagy**: Self-cleaning of expired items
- **Toxic Disposal**: Secure handling of sensitive data

```python
from operon_ai import Lysosome, WasteType

lysosome = Lysosome(auto_digest_threshold=100)

# Capture failures
try:
    result = 1 / 0  # Example risky operation
except Exception as e:
    lysosome.ingest_error(e, source="risky_op", context={"step": 3})

# Secure disposal of sensitive data
lysosome.ingest_sensitive({"api_key": "sk-..."}, source="user_input")

# Process waste and extract insights
result = lysosome.digest()
recycled = lysosome.get_recycled()
print(recycled.get("last_error_type"))  # Debugging insight!

# Periodic cleanup
lysosome.autophagy()
```

### 🧠 Nucleus (LLM Integration Hub)

The decision-making center that wraps LLM providers with auto-detection, fallback, and tool integration.

**Features:**
- **Provider Auto-Detection**: Automatically selects available provider (Anthropic → OpenAI → Gemini → Mock)
- **Graceful Fallback**: Falls back to MockProvider for testing when no API keys present
- **Tool Integration**: Connect to Mitochondria for native LLM function calling
- **Audit Trail**: Complete logging of all transcriptions with energy costs
- **Multi-turn Tool Loop**: Automatic tool execution with iteration limits

```python
from operon_ai import Nucleus, Mitochondria, ProviderConfig

# Auto-detects provider from environment variables
nucleus = Nucleus()
print(f"Using: {nucleus.provider.name}")  # anthropic, openai, gemini, or mock

# Simple transcription
response = nucleus.transcribe("Explain DNA replication")
print(response.content)

# Tool integration with Mitochondria
mito = Mitochondria(silent=True)
mito.register_function(
    name="calculator",
    func=lambda expr: str(mito.metabolize(expr).atp.value),
    description="Evaluate math expressions",
    parameters_schema={
        "type": "object",
        "properties": {"expr": {"type": "string"}},
        "required": ["expr"]
    }
)

# LLM can now call tools automatically
response = nucleus.transcribe_with_tools(
    "What is 15 * 7 + 23? Use the calculator.",
    mitochondria=mito,
    config=ProviderConfig(temperature=0.0),
    max_iterations=5,
)
print(response.content)
```

### 🔌 LLM Providers

Swappable LLM backends with a unified interface:

| Provider | Model Default | Environment Variable | Features |
|----------|---------------|---------------------|----------|
| `AnthropicProvider` | claude-sonnet-4-20250514 | `ANTHROPIC_API_KEY` | Tool use, streaming |
| `OpenAIProvider` | gpt-4o-mini | `OPENAI_API_KEY` | Tool use, JSON mode |
| `GeminiProvider` | gemini-flash-latest | `GEMINI_API_KEY` | Native function calling |
| `MockProvider` | mock | (none) | Testing, deterministic responses |

```python
from operon_ai import (
    Nucleus,
    AnthropicProvider,
    OpenAIProvider,
    GeminiProvider,
    MockProvider,
)

# Explicit provider selection
nucleus = Nucleus(provider=GeminiProvider(model="gemini-flash-latest"))

# Or use auto-detection (checks env vars in order)
nucleus = Nucleus()  # Anthropic → OpenAI → Gemini → Mock
```

---

## 🧠 State Management

Biologically-inspired state systems for agents:

### 💊 Metabolism (Energy Management)

Multi-currency energy system with regeneration, debt, and sharing.

```python
from operon_ai.state import ATP_Store, MetabolicState, EnergyType

# Multiple energy currencies
metabolism = ATP_Store(
    budget=100,          # ATP for general operations
    gtp_budget=50,       # GTP for specialized tools
    nadh_reserve=30,     # NADH reserve (converts to ATP)
    regeneration_rate=5, # Regenerate 5 ATP/second
    max_debt=20,         # Allow energy debt
)

# Consume energy for operations
metabolism.consume(10, "llm_call", EnergyType.ATP)
metabolism.consume(20, "tool_use", EnergyType.GTP)

# Convert reserves when low
metabolism.convert_nadh_to_atp(15)

# Transfer energy between agents
other_metabolism = ATP_Store(budget=50)
metabolism.transfer_to(other_metabolism, 10)
```

### 🧬 Genome (Immutable Configuration)

DNA-like configuration with gene expression control.

```python
from operon_ai.state import Genome, Gene, GeneType, ExpressionLevel

genome = Genome(genes=[
    Gene(name="model", value="gpt-4", gene_type=GeneType.STRUCTURAL, required=True),
    Gene(name="temperature", value=0.7, gene_type=GeneType.REGULATORY),
    Gene(name="debug_mode", value=True, gene_type=GeneType.CONDITIONAL),
])

# Silence a gene without changing it
genome.silence_gene("debug_mode")

# Get active configuration
config = genome.express()  # Only non-silenced genes

# Create child with mutations
child = genome.replicate(mutations={"temperature": 0.9})
```

### 🕰️ Telomere (Lifecycle Management)

Agent lifespan tracking with senescence and renewal.

```python
from operon_ai.state import Telomere, LifecyclePhase

telomere = Telomere(
    max_operations=1000,
    error_threshold=50,
    allow_renewal=True,
)

# Each operation shortens telomeres
for i in range(10):
    if not telomere.tick():  # Returns False when senescent
        break
    print(f"Operation {i}: {telomere.remaining} remaining")

# Renew agent (like telomerase)
if telomere.get_phase() == LifecyclePhase.SENESCENT:
    telomere.renew(amount=500)  # Extend lifespan
```

### 📝 Histone (Epigenetic Memory)

Multi-type memory with decay, reinforcement, and inheritance.

```python
from operon_ai.state import HistoneStore, MarkerType, MarkerStrength

memory = HistoneStore(enable_decay=True, decay_rate=0.1)

# Different marker types for different persistence
memory.methylate("user_preference", {"theme": "dark"},
                 marker_type=MarkerType.METHYLATION,  # Permanent
                 strength=MarkerStrength.STRONG)

memory.methylate("session_context", {"topic": "ML"},
                 marker_type=MarkerType.ACETYLATION,  # Temporary
                 tags=["context"])

# Semantic recall by tags
results = memory.retrieve_by_tags(["context"])

# Memory inheritance to child agents
child_memory = memory.create_child(inherit_methylations=True)
```

---

## 🔬 Network Topologies

Higher-order patterns that wire agents together:

### Coherent Feed-Forward Loop (CFFL)

**Two-key execution guardrail**: an action proceeds only if the executor and a risk assessor both permit it.

Note: the AND gate provides an interlock, not true independence—risk reduction depends on assessor diversity/tool-grounding.

```python
from operon_ai import ATP_Store
from operon_ai.topology import CoherentFeedForwardLoop, GateLogic

energy = ATP_Store(budget=100)
guardrail = CoherentFeedForwardLoop(
    budget=energy,
    gate_logic=GateLogic.AND,           # Both must agree
    enable_circuit_breaker=True,         # Prevent cascade failures
    enable_cache=True,                   # Cache decisions
)

result = guardrail.run("Deploy to production")
if result.blocked:
    print(f"Blocked: {result.block_reason}")
else:
    # Proof-carrying token bound to this request (two-key execution)
    print(f"Approval issuer: {result.approval_token.issuer}")
```

### Quorum Sensing

Multi-agent consensus with voting strategies and reliability tracking.

Note: quorum only helps if voters are not strongly correlated (use diverse models, tool checks, and/or data partitioning).

```python
from operon_ai import ATP_Store
from operon_ai.topology import QuorumSensing, VotingStrategy

budget = ATP_Store(budget=100)
quorum = QuorumSensing(
    n_agents=5,
    budget=budget,
    strategy=VotingStrategy.WEIGHTED,  # Weight-adjusted voting
)

# Set agent weights (experts have more influence)
quorum.set_agent_weight("Expert_Agent", 2.0)

result = quorum.run_vote("Should we deploy to production?")
print(f"Decision: {result.decision.value}")
print(f"Confidence: {result.confidence_score:.1%}")
```

### Cascade (Signal Amplification)

Multi-stage processing with checkpoints and amplification.

```python
from operon_ai.topology import Cascade, CascadeStage, MAPKCascade

cascade = Cascade(name="DataPipeline")

cascade.add_stage(CascadeStage(
    name="validate",
    processor=lambda x: x if x > 0 else None,  # Only positive values
    checkpoint=lambda x: x is not None,  # Gate
))

cascade.add_stage(CascadeStage(
    name="transform",
    processor=lambda x: x * 2,  # Double the value
    amplification=2.0,  # Signal amplification
))

result = cascade.run(10)  # Input value
print(f"Amplification: {result.total_amplification}x")

# Or use pre-built MAPK cascade
mapk = MAPKCascade(tier1_amplification=10.0)
```

### Oscillator (Periodic Tasks)

Biological rhythms for scheduled operations.

```python
from operon_ai.topology import Oscillator, HeartbeatOscillator, OscillatorPhase

# Define your periodic actions
def health_check():
    print("💓 Health check: OK")

def do_work():
    print("⚙️ Working...")

def do_rest():
    print("😴 Resting...")

# Heartbeat for health checks (1 beat per second)
heartbeat = HeartbeatOscillator(
    beats_per_minute=60,
    on_beat=health_check,
)
heartbeat.start()

# Custom work/rest cycle
osc = Oscillator(frequency_hz=0.1)  # 10 second period
osc.add_phase(OscillatorPhase(name="work", duration_seconds=7, action=do_work))
osc.add_phase(OscillatorPhase(name="rest", duration_seconds=3, action=do_rest))
osc.start()

# Stop when done (oscillators run in background threads)
# heartbeat.stop()
# osc.stop()
```

---

## 🧷 Typed Wiring (WAgent)

Validate wiring diagrams up-front: type flow (`DataType`), integrity flow (`IntegrityLabel`), and aggregate effects (`Capability`).

```python
from operon_ai import (
    WiringDiagram, ModuleSpec, PortType,
    DataType, IntegrityLabel, Capability,
)

diagram = WiringDiagram()
diagram.add_module(ModuleSpec(
    name="membrane",
    outputs={"clean_text": PortType(DataType.TEXT, IntegrityLabel.VALIDATED)},
))
diagram.add_module(ModuleSpec(
    name="executor",
    inputs={"prompt": PortType(DataType.TEXT, IntegrityLabel.VALIDATED)},
    capabilities={Capability.EXEC_CODE},
))

diagram.connect("membrane", "clean_text", "executor", "prompt")  # raises WiringError if invalid
print(diagram.required_capabilities())
```

## 📦 Installation

```bash
pip install operon-ai
```

## 🔬 Examples

Explore the `examples/` directory for runnable demonstrations:

### Basic Topologies

| Example | Pattern | Description |
|---------|---------|-------------|
| [`01_code_review_bot.py`](examples/01_code_review_bot.py) | CFFL | Dual-check guardrails (executor + risk assessor) |
| [`02_multi_model_consensus.py`](examples/02_multi_model_consensus.py) | Quorum | Multi-agent voting with threshold consensus |
| [`03_structured_extraction.py`](examples/03_structured_extraction.py) | Chaperone | Schema validation for raw text |
| [`04_budget_aware_agent.py`](examples/04_budget_aware_agent.py) | ATP | Resource management with graceful degradation |
| [`05_secure_chat_with_memory.py`](examples/05_secure_chat_with_memory.py) | Membrane+Histone | Input filtering + learned memory |
| [`06_sql_query_validation.py`](examples/06_sql_query_validation.py) | Chaperone | Domain-specific SQL validation |

### Advanced Organelles

| Example | Organelle | Description |
|---------|-----------|-------------|
| [`07_adaptive_membrane_defense.py`](examples/07_adaptive_membrane_defense.py) | Membrane | Adaptive immunity, antibody transfer, rate limiting |
| [`08_multi_pathway_mitochondria.py`](examples/08_multi_pathway_mitochondria.py) | Mitochondria | Safe AST computation, tool registry, ROS management |
| [`09_advanced_chaperone_folding.py`](examples/09_advanced_chaperone_folding.py) | Chaperone | Multi-strategy folding, confidence scoring |
| [`10_ribosome_prompt_factory.py`](examples/10_ribosome_prompt_factory.py) | Ribosome | Template synthesis, conditionals, loops, includes |
| [`11_lysosome_waste_management.py`](examples/11_lysosome_waste_management.py) | Lysosome | Cleanup, recycling, autophagy, toxic disposal |
| [`12_complete_cell_simulation.py`](examples/12_complete_cell_simulation.py) | **All** | Complete cellular lifecycle with all organelles |

### State Management & Topologies

| Example | System | Description |
|---------|--------|-------------|
| [`13_advanced_metabolism.py`](examples/13_advanced_metabolism.py) | Metabolism | Multi-currency (ATP/GTP/NADH), debt, regeneration, sharing |
| [`14_epigenetic_memory.py`](examples/14_epigenetic_memory.py) | Histone | Marker types, decay, reinforcement, inheritance |
| [`15_genome_telomere_lifecycle.py`](examples/15_genome_telomere_lifecycle.py) | Genome+Telomere | Immutable config, gene expression, lifecycle management |
| [`16_network_topologies.py`](examples/16_network_topologies.py) | Topologies | Cascade, Oscillator, enhanced QuorumSensing |
| [`17_wagent_typed_wiring.py`](examples/17_wagent_typed_wiring.py) | WAgent | Typed wiring checker (integrity + capabilities) |
| [`26_wiring_diagram_guarded_toolchain.py`](examples/26_wiring_diagram_guarded_toolchain.py) | WAgent | Integrity upgrades, adapters, and approval-gated tool wiring |
| [`27_wiring_diagram_resource_allocator.py`](examples/27_wiring_diagram_resource_allocator.py) | WAgent | Resource-budget wiring with validation, fanout, and approvals |
| [`28_wiring_diagram_quorum_consensus.py`](examples/28_wiring_diagram_quorum_consensus.py) | WAgent | Multi-agent votes aggregated into a trusted approval token |
| [`29_wiring_diagram_safe_tool_calls.py`](examples/29_wiring_diagram_safe_tool_calls.py) | WAgent | Approval-gated tool calls with validated planning |
| [`30_wiring_diagram_composed_system.py`](examples/30_wiring_diagram_composed_system.py) | WAgent | Composition via namespaced sub-diagrams and cross-links |
| [`31_wiring_diagram_composed_effects.py`](examples/31_wiring_diagram_composed_effects.py) | WAgent | Composed system with net + filesystem effect aggregation |
| [`32_wiring_diagram_execution.py`](examples/32_wiring_diagram_execution.py) | WAgent | Minimal runtime executor for typed wiring diagrams |
| [`33_wiring_diagram_execution_failures.py`](examples/33_wiring_diagram_execution_failures.py) | WAgent | Runtime failure cases (missing approval, type mismatch) |
| [`34_wiring_diagram_nucleus_llm.py`](examples/34_wiring_diagram_nucleus_llm.py) | WAgent | Nucleus LLM wiring with context, validation, and feedback |
| [`35_wiring_diagram_nucleus_execution.py`](examples/35_wiring_diagram_nucleus_execution.py) | WAgent | Execute a nucleus wiring with guarded tool flow |
| [`36_wiring_diagram_multi_gemini_allocation.py`](examples/36_wiring_diagram_multi_gemini_allocation.py) | WAgent | Resource allocation across multiple Gemini agents |
| [`wiring_diagrams.md`](examples/wiring_diagrams.md) | WAgent | ASCII + Mermaid wiring diagrams for examples 17, 26-37 |

### LLM Integration

| Example | System | Description |
|---------|--------|-------------|
| [`18_cell_integrity_demo.py`](examples/18_cell_integrity_demo.py) | Integrity | Quality, Surveillance, and Coordination systems |
| [`19_llm_code_assistant.py`](examples/19_llm_code_assistant.py) | Nucleus+CFFL | Code generation with two-phase safety review |
| [`20_llm_memory_chat.py`](examples/20_llm_memory_chat.py) | Nucleus+Histone | Conversational AI with epigenetic memory |
| [`21_llm_living_cell.py`](examples/21_llm_living_cell.py) | **Full Cell** | Complete lifecycle with LLM, memory, and aging |
| [`22_llm_tool_use.py`](examples/22_llm_tool_use.py) | Nucleus+Mitochondria | LLM function calling with tool integration |

### Complex Systems

| Example | System | Description |
|---------|--------|-------------|
| [`23_resilient_incident_response.py`](examples/23_resilient_incident_response.py) | Multi-organelle | Incident triage, planning, coordinated execution, and quality gating |
| [`24_governed_release_train.py`](examples/24_governed_release_train.py) | Governance | Quorum + CFFL + feedback control with coordinated rollout |
| [`25_resource_allocation_tradeoffs.py`](examples/25_resource_allocation_tradeoffs.py) | Resource Allocation | Nutrient, machinery, and energy budgeting with trade-offs |
| [`37_metabolic_swarm_budgeting.py`](examples/37_metabolic_swarm_budgeting.py) | Coalgebra | Metabolic swarm with shared budget and halting guarantee |

Run any example:

```bash
# Clone and install
git clone https://github.com/coredipper/operon.git
cd operon
pip install -e .

# Run examples
python examples/07_adaptive_membrane_defense.py
python examples/12_complete_cell_simulation.py
```

---

## 📚 Theoretical Background

Operon is grounded in the observation that Gene Regulatory Networks (GRNs) and agentic architectures share structural similarities. Both can be modeled as typed wiring diagrams—graphs where nodes are components and edges carry typed signals. The table below maps biological concepts to their software and mathematical equivalents.

| Biological Concept | Software Equivalent | Mathematical Object |
|-------------------|---------------------|---------------------|
| Gene | Agent / System Prompt | Polynomial Functor (P) |
| Promoter | Context Schema | Lens (S→V) |
| Signal | Message / User Input | Type (T) |
| Epigenetics | RAG / Vector Store | State Monad (M) |
| Membrane | Input Filter | Predicate (T → Bool) |
| Ribosome | Template Engine | String Functor |
| Mitochondria | Tool Use | Effect Monad (capabilities) |
| Nucleus | LLM Provider | Decision Functor (prompt → response) |

---

## 🏗️ Architecture

```
┌─────────────────────────────────────────────────────────────┐
│                         CELL (Agent)                        │
├─────────────────────────────────────────────────────────────┤
│  ┌─────────────┐    ┌─────────────┐    ┌──────────────┐     │
│  │  MEMBRANE   │───▶│   NUCLEUS   │───▶│ MITOCHONDRIA │     │
│  │  (Filter)   │    │ (LLM/Think) │◀───│   (Tools)    │     │
│  └─────────────┘    └─────────────┘    └──────────────┘     │
│         │                  │                  │             │
│         │                  ▼                  │             │
│         │           ┌─────────────┐           │             │
│         │           │  RIBOSOME   │           │             │
│         │           │ (Templates) │           │             │
│         │           └─────────────┘           │             │
│         │                  │                  │             │
│         │                  ▼                  ▼             │
│         │           ┌─────────────┐    ┌─────────────┐      │
│         │           │  CHAPERONE  │    │   HISTONE   │      │
│         │           │ (Validate)  │    │  (Memory)   │      │
│         │           └─────────────┘    └─────────────┘      │
│         │                  │                                │
│         ▼                  ▼                                │
│  ┌─────────────────────────────────────────────────────┐    │
│  │                      LYSOSOME                       │    │
│  │              (Cleanup & Recycling)                  │    │
│  └─────────────────────────────────────────────────────┘    │
└─────────────────────────────────────────────────────────────┘
```

---

## 🤝 Contributing

Contributions welcome. Current areas of interest:

- **Quorum algorithms**: Additional voting strategies and Byzantine fault tolerance
- **Provider integrations**: New LLM backends beyond Anthropic/OpenAI/Gemini
- **Network motifs**: Implementations of additional biological control patterns

1. Fork the repo
2. Create your feature branch (`git checkout -b feature/your-feature`)
3. Commit your changes
4. Open a Pull Request

## 📄 License

Distributed under the MIT License. See LICENSE for more information.
