/* Generated by Cython 0.29.21 */

/* BEGIN: Cython Metadata
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#ifndef PyObject_Unicode
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#if PY_MAJOR_VERSION >= 3
  #define __Pyx_PyBaseString_Check(obj) PyUnicode_Check(obj)
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#if PY_VERSION_HEX >= 0x030900A4
  #define __Pyx_SET_REFCNT(obj, refcnt) Py_SET_REFCNT(obj, refcnt)
  #define __Pyx_SET_SIZE(obj, size) Py_SET_SIZE(obj, size)
#else
  #define __Pyx_SET_REFCNT(obj, refcnt) Py_REFCNT(obj) = (refcnt)
  #define __Pyx_SET_SIZE(obj, size) Py_SIZE(obj) = (size)
#endif
#if CYTHON_ASSUME_SAFE_MACROS
  #define __Pyx_PySequence_SIZE(seq)  Py_SIZE(seq)
#else
  #define __Pyx_PySequence_SIZE(seq)  PySequence_Size(seq)
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#if PY_MAJOR_VERSION >= 3
  #define PyIntObject                  PyLongObject
  #define PyInt_Type                   PyLong_Type
  #define PyInt_Check(op)              PyLong_Check(op)
  #define PyInt_CheckExact(op)         PyLong_CheckExact(op)
  #define PyInt_FromString             PyLong_FromString
  #define PyInt_FromUnicode            PyLong_FromUnicode
  #define PyInt_FromLong               PyLong_FromLong
  #define PyInt_FromSize_t             PyLong_FromSize_t
  #define PyInt_FromSsize_t            PyLong_FromSsize_t
  #define PyInt_AsLong                 PyLong_AsLong
  #define PyInt_AS_LONG                PyLong_AS_LONG
  #define PyInt_AsSsize_t              PyLong_AsSsize_t
  #define PyInt_AsUnsignedLongMask     PyLong_AsUnsignedLongMask
  #define PyInt_AsUnsignedLongLongMask PyLong_AsUnsignedLongLongMask
  #define PyNumber_Int                 PyNumber_Long
#endif
#if PY_MAJOR_VERSION >= 3
  #define PyBoolObject                 PyLongObject
#endif
#if PY_MAJOR_VERSION >= 3 && CYTHON_COMPILING_IN_PYPY
  #ifndef PyUnicode_InternFromString
    #define PyUnicode_InternFromString(s) PyUnicode_FromString(s)
  #endif
#endif
#if PY_VERSION_HEX < 0x030200A4
  typedef long Py_hash_t;
  #define __Pyx_PyInt_FromHash_t PyInt_FromLong
  #define __Pyx_PyInt_AsHash_t   PyInt_AsLong
#else
  #define __Pyx_PyInt_FromHash_t PyInt_FromSsize_t
  #define __Pyx_PyInt_AsHash_t   PyInt_AsSsize_t
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#if PY_MAJOR_VERSION >= 3
  #define __Pyx_PyMethod_New(func, self, klass) ((self) ? ((void)(klass), PyMethod_New(func, self)) : __Pyx_NewRef(func))
#else
  #define __Pyx_PyMethod_New(func, self, klass) PyMethod_New(func, self, klass)
#endif
#if CYTHON_USE_ASYNC_SLOTS
  #if PY_VERSION_HEX >= 0x030500B1
    #define __Pyx_PyAsyncMethodsStruct PyAsyncMethods
    #define __Pyx_PyType_AsAsync(obj) (Py_TYPE(obj)->tp_as_async)
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    #define __Pyx_PyType_AsAsync(obj) ((__Pyx_PyAsyncMethodsStruct*) (Py_TYPE(obj)->tp_reserved))
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#else
  #define __Pyx_PyType_AsAsync(obj) NULL
#endif
#ifndef __Pyx_PyAsyncMethodsStruct
    typedef struct {
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        unaryfunc am_aiter;
        unaryfunc am_anext;
    } __Pyx_PyAsyncMethodsStruct;
#endif

#if defined(WIN32) || defined(MS_WINDOWS)
  #define _USE_MATH_DEFINES
#endif
#include <math.h>
#ifdef NAN
#define __PYX_NAN() ((float) NAN)
#else
static CYTHON_INLINE float __PYX_NAN() {
  float value;
  memset(&value, 0xFF, sizeof(value));
  return value;
}
#endif
#if defined(__CYGWIN__) && defined(_LDBL_EQ_DBL)
#define __Pyx_truncl trunc
#else
#define __Pyx_truncl truncl
#endif

#define __PYX_MARK_ERR_POS(f_index, lineno) \
    { __pyx_filename = __pyx_f[f_index]; (void)__pyx_filename; __pyx_lineno = lineno; (void)__pyx_lineno; __pyx_clineno = __LINE__; (void)__pyx_clineno; }
#define __PYX_ERR(f_index, lineno, Ln_error) \
    { __PYX_MARK_ERR_POS(f_index, lineno) goto Ln_error; }

#ifndef __PYX_EXTERN_C
  #ifdef __cplusplus
    #define __PYX_EXTERN_C extern "C"
  #else
    #define __PYX_EXTERN_C extern
  #endif
#endif

#define __PYX_HAVE__ms_deisotope___c__peak_dependency_network__subgraph
#define __PYX_HAVE_API__ms_deisotope___c__peak_dependency_network__subgraph
/* Early includes */
#include <string.h>
#include <stdio.h>
#include "numpy/arrayobject.h"
#include "numpy/ufuncobject.h"

    /* NumPy API declarations from "numpy/__init__.pxd" */
    
#ifdef _OPENMP
#include <omp.h>
#endif /* _OPENMP */

#if defined(PYREX_WITHOUT_ASSERTIONS) && !defined(CYTHON_WITHOUT_ASSERTIONS)
#define CYTHON_WITHOUT_ASSERTIONS
#endif

typedef struct {PyObject **p; const char *s; const Py_ssize_t n; const char* encoding;
                const char is_unicode; const char is_str; const char intern; } __Pyx_StringTabEntry;

#define __PYX_DEFAULT_STRING_ENCODING_IS_ASCII 0
#define __PYX_DEFAULT_STRING_ENCODING_IS_UTF8 0
#define __PYX_DEFAULT_STRING_ENCODING_IS_DEFAULT (PY_MAJOR_VERSION >= 3 && __PYX_DEFAULT_STRING_ENCODING_IS_UTF8)
#define __PYX_DEFAULT_STRING_ENCODING ""
#define __Pyx_PyObject_FromString __Pyx_PyBytes_FromString
#define __Pyx_PyObject_FromStringAndSize __Pyx_PyBytes_FromStringAndSize
#define __Pyx_uchar_cast(c) ((unsigned char)c)
#define __Pyx_long_cast(x) ((long)x)
#define __Pyx_fits_Py_ssize_t(v, type, is_signed)  (\
    (sizeof(type) < sizeof(Py_ssize_t))  ||\
    (sizeof(type) > sizeof(Py_ssize_t) &&\
          likely(v < (type)PY_SSIZE_T_MAX ||\
                 v == (type)PY_SSIZE_T_MAX)  &&\
          (!is_signed || likely(v > (type)PY_SSIZE_T_MIN ||\
                                v == (type)PY_SSIZE_T_MIN)))  ||\
    (sizeof(type) == sizeof(Py_ssize_t) &&\
          (is_signed || likely(v < (type)PY_SSIZE_T_MAX ||\
                               v == (type)PY_SSIZE_T_MAX)))  )
static CYTHON_INLINE int __Pyx_is_valid_index(Py_ssize_t i, Py_ssize_t limit) {
    return (size_t) i < (size_t) limit;
}
#if defined (__cplusplus) && __cplusplus >= 201103L
    #include <cstdlib>
    #define __Pyx_sst_abs(value) std::abs(value)
#elif SIZEOF_INT >= SIZEOF_SIZE_T
    #define __Pyx_sst_abs(value) abs(value)
#elif SIZEOF_LONG >= SIZEOF_SIZE_T
    #define __Pyx_sst_abs(value) labs(value)
#elif defined (_MSC_VER)
    #define __Pyx_sst_abs(value) ((Py_ssize_t)_abs64(value))
#elif defined (__STDC_VERSION__) && __STDC_VERSION__ >= 199901L
    #define __Pyx_sst_abs(value) llabs(value)
#elif defined (__GNUC__)
    #define __Pyx_sst_abs(value) __builtin_llabs(value)
#else
    #define __Pyx_sst_abs(value) ((value<0) ? -value : value)
#endif
static CYTHON_INLINE const char* __Pyx_PyObject_AsString(PyObject*);
static CYTHON_INLINE const char* __Pyx_PyObject_AsStringAndSize(PyObject*, Py_ssize_t* length);
#define __Pyx_PyByteArray_FromString(s) PyByteArray_FromStringAndSize((const char*)s, strlen((const char*)s))
#define __Pyx_PyByteArray_FromStringAndSize(s, l) PyByteArray_FromStringAndSize((const char*)s, l)
#define __Pyx_PyBytes_FromString        PyBytes_FromString
#define __Pyx_PyBytes_FromStringAndSize PyBytes_FromStringAndSize
static CYTHON_INLINE PyObject* __Pyx_PyUnicode_FromString(const char*);
#if PY_MAJOR_VERSION < 3
    #define __Pyx_PyStr_FromString        __Pyx_PyBytes_FromString
    #define __Pyx_PyStr_FromStringAndSize __Pyx_PyBytes_FromStringAndSize
#else
    #define __Pyx_PyStr_FromString        __Pyx_PyUnicode_FromString
    #define __Pyx_PyStr_FromStringAndSize __Pyx_PyUnicode_FromStringAndSize
#endif
#define __Pyx_PyBytes_AsWritableString(s)     ((char*) PyBytes_AS_STRING(s))
#define __Pyx_PyBytes_AsWritableSString(s)    ((signed char*) PyBytes_AS_STRING(s))
#define __Pyx_PyBytes_AsWritableUString(s)    ((unsigned char*) PyBytes_AS_STRING(s))
#define __Pyx_PyBytes_AsString(s)     ((const char*) PyBytes_AS_STRING(s))
#define __Pyx_PyBytes_AsSString(s)    ((const signed char*) PyBytes_AS_STRING(s))
#define __Pyx_PyBytes_AsUString(s)    ((const unsigned char*) PyBytes_AS_STRING(s))
#define __Pyx_PyObject_AsWritableString(s)    ((char*) __Pyx_PyObject_AsString(s))
#define __Pyx_PyObject_AsWritableSString(s)    ((signed char*) __Pyx_PyObject_AsString(s))
#define __Pyx_PyObject_AsWritableUString(s)    ((unsigned char*) __Pyx_PyObject_AsString(s))
#define __Pyx_PyObject_AsSString(s)    ((const signed char*) __Pyx_PyObject_AsString(s))
#define __Pyx_PyObject_AsUString(s)    ((const unsigned char*) __Pyx_PyObject_AsString(s))
#define __Pyx_PyObject_FromCString(s)  __Pyx_PyObject_FromString((const char*)s)
#define __Pyx_PyBytes_FromCString(s)   __Pyx_PyBytes_FromString((const char*)s)
#define __Pyx_PyByteArray_FromCString(s)   __Pyx_PyByteArray_FromString((const char*)s)
#define __Pyx_PyStr_FromCString(s)     __Pyx_PyStr_FromString((const char*)s)
#define __Pyx_PyUnicode_FromCString(s) __Pyx_PyUnicode_FromString((const char*)s)
static CYTHON_INLINE size_t __Pyx_Py_UNICODE_strlen(const Py_UNICODE *u) {
    const Py_UNICODE *u_end = u;
    while (*u_end++) ;
    return (size_t)(u_end - u - 1);
}
#define __Pyx_PyUnicode_FromUnicode(u)       PyUnicode_FromUnicode(u, __Pyx_Py_UNICODE_strlen(u))
#define __Pyx_PyUnicode_FromUnicodeAndLength PyUnicode_FromUnicode
#define __Pyx_PyUnicode_AsUnicode            PyUnicode_AsUnicode
#define __Pyx_NewRef(obj) (Py_INCREF(obj), obj)
#define __Pyx_Owned_Py_None(b) __Pyx_NewRef(Py_None)
static CYTHON_INLINE PyObject * __Pyx_PyBool_FromLong(long b);
static CYTHON_INLINE int __Pyx_PyObject_IsTrue(PyObject*);
static CYTHON_INLINE int __Pyx_PyObject_IsTrueAndDecref(PyObject*);
static CYTHON_INLINE PyObject* __Pyx_PyNumber_IntOrLong(PyObject* x);
#define __Pyx_PySequence_Tuple(obj)\
    (likely(PyTuple_CheckExact(obj)) ? __Pyx_NewRef(obj) : PySequence_Tuple(obj))
static CYTHON_INLINE Py_ssize_t __Pyx_PyIndex_AsSsize_t(PyObject*);
static CYTHON_INLINE PyObject * __Pyx_PyInt_FromSize_t(size_t);
#if CYTHON_ASSUME_SAFE_MACROS
#define __pyx_PyFloat_AsDouble(x) (PyFloat_CheckExact(x) ? PyFloat_AS_DOUBLE(x) : PyFloat_AsDouble(x))
#else
#define __pyx_PyFloat_AsDouble(x) PyFloat_AsDouble(x)
#endif
#define __pyx_PyFloat_AsFloat(x) ((float) __pyx_PyFloat_AsDouble(x))
#if PY_MAJOR_VERSION >= 3
#define __Pyx_PyNumber_Int(x) (PyLong_CheckExact(x) ? __Pyx_NewRef(x) : PyNumber_Long(x))
#else
#define __Pyx_PyNumber_Int(x) (PyInt_CheckExact(x) ? __Pyx_NewRef(x) : PyNumber_Int(x))
#endif
#define __Pyx_PyNumber_Float(x) (PyFloat_CheckExact(x) ? __Pyx_NewRef(x) : PyNumber_Float(x))
#if PY_MAJOR_VERSION < 3 && __PYX_DEFAULT_STRING_ENCODING_IS_ASCII
static int __Pyx_sys_getdefaultencoding_not_ascii;
static int __Pyx_init_sys_getdefaultencoding_params(void) {
    PyObject* sys;
    PyObject* default_encoding = NULL;
    PyObject* ascii_chars_u = NULL;
    PyObject* ascii_chars_b = NULL;
    const char* default_encoding_c;
    sys = PyImport_ImportModule("sys");
    if (!sys) goto bad;
    default_encoding = PyObject_CallMethod(sys, (char*) "getdefaultencoding", NULL);
    Py_DECREF(sys);
    if (!default_encoding) goto bad;
    default_encoding_c = PyBytes_AsString(default_encoding);
    if (!default_encoding_c) goto bad;
    if (strcmp(default_encoding_c, "ascii") == 0) {
        __Pyx_sys_getdefaultencoding_not_ascii = 0;
    } else {
        char ascii_chars[128];
        int c;
        for (c = 0; c < 128; c++) {
            ascii_chars[c] = c;
        }
        __Pyx_sys_getdefaultencoding_not_ascii = 1;
        ascii_chars_u = PyUnicode_DecodeASCII(ascii_chars, 128, NULL);
        if (!ascii_chars_u) goto bad;
        ascii_chars_b = PyUnicode_AsEncodedString(ascii_chars_u, default_encoding_c, NULL);
        if (!ascii_chars_b || !PyBytes_Check(ascii_chars_b) || memcmp(ascii_chars, PyBytes_AS_STRING(ascii_chars_b), 128) != 0) {
            PyErr_Format(
                PyExc_ValueError,
                "This module compiled with c_string_encoding=ascii, but default encoding '%.200s' is not a superset of ascii.",
                default_encoding_c);
            goto bad;
        }
        Py_DECREF(ascii_chars_u);
        Py_DECREF(ascii_chars_b);
    }
    Py_DECREF(default_encoding);
    return 0;
bad:
    Py_XDECREF(default_encoding);
    Py_XDECREF(ascii_chars_u);
    Py_XDECREF(ascii_chars_b);
    return -1;
}
#endif
#if __PYX_DEFAULT_STRING_ENCODING_IS_DEFAULT && PY_MAJOR_VERSION >= 3
#define __Pyx_PyUnicode_FromStringAndSize(c_str, size) PyUnicode_DecodeUTF8(c_str, size, NULL)
#else
#define __Pyx_PyUnicode_FromStringAndSize(c_str, size) PyUnicode_Decode(c_str, size, __PYX_DEFAULT_STRING_ENCODING, NULL)
#if __PYX_DEFAULT_STRING_ENCODING_IS_DEFAULT
static char* __PYX_DEFAULT_STRING_ENCODING;
static int __Pyx_init_sys_getdefaultencoding_params(void) {
    PyObject* sys;
    PyObject* default_encoding = NULL;
    char* default_encoding_c;
    sys = PyImport_ImportModule("sys");
    if (!sys) goto bad;
    default_encoding = PyObject_CallMethod(sys, (char*) (const char*) "getdefaultencoding", NULL);
    Py_DECREF(sys);
    if (!default_encoding) goto bad;
    default_encoding_c = PyBytes_AsString(default_encoding);
    if (!default_encoding_c) goto bad;
    __PYX_DEFAULT_STRING_ENCODING = (char*) malloc(strlen(default_encoding_c) + 1);
    if (!__PYX_DEFAULT_STRING_ENCODING) goto bad;
    strcpy(__PYX_DEFAULT_STRING_ENCODING, default_encoding_c);
    Py_DECREF(default_encoding);
    return 0;
bad:
    Py_XDECREF(default_encoding);
    return -1;
}
#endif
#endif


/* Test for GCC > 2.95 */
#if defined(__GNUC__)     && (__GNUC__ > 2 || (__GNUC__ == 2 && (__GNUC_MINOR__ > 95)))
  #define likely(x)   __builtin_expect(!!(x), 1)
  #define unlikely(x) __builtin_expect(!!(x), 0)
#else /* !__GNUC__ or GCC < 2.95 */
  #define likely(x)   (x)
  #define unlikely(x) (x)
#endif /* __GNUC__ */
static CYTHON_INLINE void __Pyx_pretend_to_initialize(void* ptr) { (void)ptr; }

static PyObject *__pyx_m = NULL;
static PyObject *__pyx_d;
static PyObject *__pyx_b;
static PyObject *__pyx_cython_runtime = NULL;
static PyObject *__pyx_empty_tuple;
static PyObject *__pyx_empty_bytes;
static PyObject *__pyx_empty_unicode;
static int __pyx_lineno;
static int __pyx_clineno = 0;
static const char * __pyx_cfilenm= __FILE__;
static const char *__pyx_filename;

/* Header.proto */
#if !defined(CYTHON_CCOMPLEX)
  #if defined(__cplusplus)
    #define CYTHON_CCOMPLEX 1
  #elif defined(_Complex_I)
    #define CYTHON_CCOMPLEX 1
  #else
    #define CYTHON_CCOMPLEX 0
  #endif
#endif
#if CYTHON_CCOMPLEX
  #ifdef __cplusplus
    #include <complex>
  #else
    #include <complex.h>
  #endif
#endif
#if CYTHON_CCOMPLEX && !defined(__cplusplus) && defined(__sun__) && defined(__GNUC__)
  #undef _Complex_I
  #define _Complex_I 1.0fj
#endif


static const char *__pyx_f[] = {
  "ms_deisotope/_c/peak_dependency_network/subgraph.pyx",
  "ms_deisotope/_c/peak_dependency_network/subgraph.pxd",
  "stringsource",
  "__init__.pxd",
  "type.pxd",
  "ms_deisotope/_c/peak_dependency_network/intervals.pxd",
  "composition.pxd",
  "isotopic_distribution.pxd",
  "peak_set.pxd",
  "peak_index.pxd",
  "ms_deisotope/_c/averagine.pxd",
  "ms_deisotope/_c/deconvoluter_base.pxd",
  "ms_deisotope/_c/scoring.pxd",
};

/* "brainpy/_c/composition.pxd":3
 * from brainpy.mass_dict import nist_mass as __nist_mass
 * 
 * ctypedef long count_type             # <<<<<<<<<<<<<<
 * 
 * cdef dict nist_mass
 */
typedef long __pyx_t_7brainpy_2_c_11composition_count_type;

/* "../../../../../tmp/pip-build-env-aps34_7m/overlay/lib/python3.9/site-packages/numpy/__init__.pxd":689
 * # in Cython to enable them only on the right systems.
 * 
 * ctypedef npy_int8       int8_t             # <<<<<<<<<<<<<<
 * ctypedef npy_int16      int16_t
 * ctypedef npy_int32      int32_t
 */
typedef npy_int8 __pyx_t_5numpy_int8_t;

/* "../../../../../tmp/pip-build-env-aps34_7m/overlay/lib/python3.9/site-packages/numpy/__init__.pxd":690
 * 
 * ctypedef npy_int8       int8_t
 * ctypedef npy_int16      int16_t             # <<<<<<<<<<<<<<
 * ctypedef npy_int32      int32_t
 * ctypedef npy_int64      int64_t
 */
typedef npy_int16 __pyx_t_5numpy_int16_t;

/* "../../../../../tmp/pip-build-env-aps34_7m/overlay/lib/python3.9/site-packages/numpy/__init__.pxd":691
 * ctypedef npy_int8       int8_t
 * ctypedef npy_int16      int16_t
 * ctypedef npy_int32      int32_t             # <<<<<<<<<<<<<<
 * ctypedef npy_int64      int64_t
 * #ctypedef npy_int96      int96_t
 */
typedef npy_int32 __pyx_t_5numpy_int32_t;

/* "../../../../../tmp/pip-build-env-aps34_7m/overlay/lib/python3.9/site-packages/numpy/__init__.pxd":692
 * ctypedef npy_int16      int16_t
 * ctypedef npy_int32      int32_t
 * ctypedef npy_int64      int64_t             # <<<<<<<<<<<<<<
 * #ctypedef npy_int96      int96_t
 * #ctypedef npy_int128     int128_t
 */
typedef npy_int64 __pyx_t_5numpy_int64_t;

/* "../../../../../tmp/pip-build-env-aps34_7m/overlay/lib/python3.9/site-packages/numpy/__init__.pxd":696
 * #ctypedef npy_int128     int128_t
 * 
 * ctypedef npy_uint8      uint8_t             # <<<<<<<<<<<<<<
 * ctypedef npy_uint16     uint16_t
 * ctypedef npy_uint32     uint32_t
 */
typedef npy_uint8 __pyx_t_5numpy_uint8_t;

/* "../../../../../tmp/pip-build-env-aps34_7m/overlay/lib/python3.9/site-packages/numpy/__init__.pxd":697
 * 
 * ctypedef npy_uint8      uint8_t
 * ctypedef npy_uint16     uint16_t             # <<<<<<<<<<<<<<
 * ctypedef npy_uint32     uint32_t
 * ctypedef npy_uint64     uint64_t
 */
typedef npy_uint16 __pyx_t_5numpy_uint16_t;

/* "../../../../../tmp/pip-build-env-aps34_7m/overlay/lib/python3.9/site-packages/numpy/__init__.pxd":698
 * ctypedef npy_uint8      uint8_t
 * ctypedef npy_uint16     uint16_t
 * ctypedef npy_uint32     uint32_t             # <<<<<<<<<<<<<<
 * ctypedef npy_uint64     uint64_t
 * #ctypedef npy_uint96     uint96_t
 */
typedef npy_uint32 __pyx_t_5numpy_uint32_t;

/* "../../../../../tmp/pip-build-env-aps34_7m/overlay/lib/python3.9/site-packages/numpy/__init__.pxd":699
 * ctypedef npy_uint16     uint16_t
 * ctypedef npy_uint32     uint32_t
 * ctypedef npy_uint64     uint64_t             # <<<<<<<<<<<<<<
 * #ctypedef npy_uint96     uint96_t
 * #ctypedef npy_uint128    uint128_t
 */
typedef npy_uint64 __pyx_t_5numpy_uint64_t;

/* "../../../../../tmp/pip-build-env-aps34_7m/overlay/lib/python3.9/site-packages/numpy/__init__.pxd":703
 * #ctypedef npy_uint128    uint128_t
 * 
 * ctypedef npy_float32    float32_t             # <<<<<<<<<<<<<<
 * ctypedef npy_float64    float64_t
 * #ctypedef npy_float80    float80_t
 */
typedef npy_float32 __pyx_t_5numpy_float32_t;

/* "../../../../../tmp/pip-build-env-aps34_7m/overlay/lib/python3.9/site-packages/numpy/__init__.pxd":704
 * 
 * ctypedef npy_float32    float32_t
 * ctypedef npy_float64    float64_t             # <<<<<<<<<<<<<<
 * #ctypedef npy_float80    float80_t
 * #ctypedef npy_float128   float128_t
 */
typedef npy_float64 __pyx_t_5numpy_float64_t;

/* "../../../../../tmp/pip-build-env-aps34_7m/overlay/lib/python3.9/site-packages/numpy/__init__.pxd":713
 * # The int types are mapped a bit surprising --
 * # numpy.int corresponds to 'l' and numpy.long to 'q'
 * ctypedef npy_long       int_t             # <<<<<<<<<<<<<<
 * ctypedef npy_longlong   long_t
 * ctypedef npy_longlong   longlong_t
 */
typedef npy_long __pyx_t_5numpy_int_t;

/* "../../../../../tmp/pip-build-env-aps34_7m/overlay/lib/python3.9/site-packages/numpy/__init__.pxd":714
 * # numpy.int corresponds to 'l' and numpy.long to 'q'
 * ctypedef npy_long       int_t
 * ctypedef npy_longlong   long_t             # <<<<<<<<<<<<<<
 * ctypedef npy_longlong   longlong_t
 * 
 */
typedef npy_longlong __pyx_t_5numpy_long_t;

/* "../../../../../tmp/pip-build-env-aps34_7m/overlay/lib/python3.9/site-packages/numpy/__init__.pxd":715
 * ctypedef npy_long       int_t
 * ctypedef npy_longlong   long_t
 * ctypedef npy_longlong   longlong_t             # <<<<<<<<<<<<<<
 * 
 * ctypedef npy_ulong      uint_t
 */
typedef npy_longlong __pyx_t_5numpy_longlong_t;

/* "../../../../../tmp/pip-build-env-aps34_7m/overlay/lib/python3.9/site-packages/numpy/__init__.pxd":717
 * ctypedef npy_longlong   longlong_t
 * 
 * ctypedef npy_ulong      uint_t             # <<<<<<<<<<<<<<
 * ctypedef npy_ulonglong  ulong_t
 * ctypedef npy_ulonglong  ulonglong_t
 */
typedef npy_ulong __pyx_t_5numpy_uint_t;

/* "../../../../../tmp/pip-build-env-aps34_7m/overlay/lib/python3.9/site-packages/numpy/__init__.pxd":718
 * 
 * ctypedef npy_ulong      uint_t
 * ctypedef npy_ulonglong  ulong_t             # <<<<<<<<<<<<<<
 * ctypedef npy_ulonglong  ulonglong_t
 * 
 */
typedef npy_ulonglong __pyx_t_5numpy_ulong_t;

/* "../../../../../tmp/pip-build-env-aps34_7m/overlay/lib/python3.9/site-packages/numpy/__init__.pxd":719
 * ctypedef npy_ulong      uint_t
 * ctypedef npy_ulonglong  ulong_t
 * ctypedef npy_ulonglong  ulonglong_t             # <<<<<<<<<<<<<<
 * 
 * ctypedef npy_intp       intp_t
 */
typedef npy_ulonglong __pyx_t_5numpy_ulonglong_t;

/* "../../../../../tmp/pip-build-env-aps34_7m/overlay/lib/python3.9/site-packages/numpy/__init__.pxd":721
 * ctypedef npy_ulonglong  ulonglong_t
 * 
 * ctypedef npy_intp       intp_t             # <<<<<<<<<<<<<<
 * ctypedef npy_uintp      uintp_t
 * 
 */
typedef npy_intp __pyx_t_5numpy_intp_t;

/* "../../../../../tmp/pip-build-env-aps34_7m/overlay/lib/python3.9/site-packages/numpy/__init__.pxd":722
 * 
 * ctypedef npy_intp       intp_t
 * ctypedef npy_uintp      uintp_t             # <<<<<<<<<<<<<<
 * 
 * ctypedef npy_double     float_t
 */
typedef npy_uintp __pyx_t_5numpy_uintp_t;

/* "../../../../../tmp/pip-build-env-aps34_7m/overlay/lib/python3.9/site-packages/numpy/__init__.pxd":724
 * ctypedef npy_uintp      uintp_t
 * 
 * ctypedef npy_double     float_t             # <<<<<<<<<<<<<<
 * ctypedef npy_double     double_t
 * ctypedef npy_longdouble longdouble_t
 */
typedef npy_double __pyx_t_5numpy_float_t;

/* "../../../../../tmp/pip-build-env-aps34_7m/overlay/lib/python3.9/site-packages/numpy/__init__.pxd":725
 * 
 * ctypedef npy_double     float_t
 * ctypedef npy_double     double_t             # <<<<<<<<<<<<<<
 * ctypedef npy_longdouble longdouble_t
 * 
 */
typedef npy_double __pyx_t_5numpy_double_t;

/* "../../../../../tmp/pip-build-env-aps34_7m/overlay/lib/python3.9/site-packages/numpy/__init__.pxd":726
 * ctypedef npy_double     float_t
 * ctypedef npy_double     double_t
 * ctypedef npy_longdouble longdouble_t             # <<<<<<<<<<<<<<
 * 
 * ctypedef npy_cfloat      cfloat_t
 */
typedef npy_longdouble __pyx_t_5numpy_longdouble_t;
/* Declarations.proto */
#if CYTHON_CCOMPLEX
  #ifdef __cplusplus
    typedef ::std::complex< float > __pyx_t_float_complex;
  #else
    typedef float _Complex __pyx_t_float_complex;
  #endif
#else
    typedef struct { float real, imag; } __pyx_t_float_complex;
#endif
static CYTHON_INLINE __pyx_t_float_complex __pyx_t_float_complex_from_parts(float, float);

/* Declarations.proto */
#if CYTHON_CCOMPLEX
  #ifdef __cplusplus
    typedef ::std::complex< double > __pyx_t_double_complex;
  #else
    typedef double _Complex __pyx_t_double_complex;
  #endif
#else
    typedef struct { double real, imag; } __pyx_t_double_complex;
#endif
static CYTHON_INLINE __pyx_t_double_complex __pyx_t_double_complex_from_parts(double, double);


/*--- Type declarations ---*/
struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_9intervals_SpanningMixin;
struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_9intervals_Interval;
struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_9intervals_IntervalTreeNode;
struct __pyx_obj_7brainpy_2_c_11composition_PyComposition;
struct __pyx_obj_7brainpy_2_c_21isotopic_distribution_TheoreticalPeak;
struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakBase;
struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_FittedPeak;
struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSet;
struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSetIndexed;
struct __pyx_obj_14ms_peak_picker_2_c_10peak_index_PeakIndex;
struct __pyx_obj_12ms_deisotope_2_c_9averagine_Averagine;
struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern;
struct __pyx_obj_12ms_deisotope_2_c_9averagine_AveragineCache;
struct __pyx_obj_12ms_deisotope_2_c_17deconvoluter_base_DeconvoluterBase;
struct __pyx_obj_12ms_deisotope_2_c_17deconvoluter_base_AveragineDeconvoluterBase;
struct __pyx_obj_12ms_deisotope_2_c_17deconvoluter_base_MultiAveragineDeconvoluterBase;
struct __pyx_obj_12ms_deisotope_2_c_17deconvoluter_base_ChargeIterator;
struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitRecord;
struct __pyx_obj_12ms_deisotope_2_c_7scoring_FitSelectorBase;
struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitterBase;
struct __pyx_obj_12ms_deisotope_2_c_7scoring_LeastSquaresFitter;
struct __pyx_obj_12ms_deisotope_2_c_7scoring_GTestFitter;
struct __pyx_obj_12ms_deisotope_2_c_7scoring_ScaledGTestFitter;
struct __pyx_obj_12ms_deisotope_2_c_7scoring_MSDeconVFitter;
struct __pyx_obj_12ms_deisotope_2_c_7scoring_PenalizedMSDeconVFitter;
struct __pyx_obj_12ms_deisotope_2_c_7scoring_FunctionScorer;
struct __pyx_obj_12ms_deisotope_2_c_7scoring_InterferenceDetection;
struct __pyx_obj_12ms_deisotope_2_c_7scoring_DistinctPatternFitter;
struct __pyx_obj_12ms_deisotope_2_c_7scoring_ScaledPenalizedMSDeconvFitter;
struct __pyx_obj_12ms_deisotope_2_c_7scoring_DotProductFitter;
struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_FitNode;
struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_ConnectedSubgraph;
struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_GreedySubgraphSelection;
struct __pyx_opt_args_7brainpy_2_c_11composition_neutral_mass;
struct __pyx_opt_args_7brainpy_2_c_11composition_mass_charge_ratio;
struct __pyx_t_7brainpy_2_c_11composition_Isotope;
struct __pyx_t_7brainpy_2_c_11composition_IsotopeMap;
struct __pyx_t_7brainpy_2_c_11composition_Element;
struct __pyx_t_7brainpy_2_c_11composition_ElementHashBucket;
struct __pyx_t_7brainpy_2_c_11composition_ElementHashTable;
struct __pyx_t_7brainpy_2_c_11composition_Composition;
struct __pyx_opt_args_7brainpy_2_c_11composition_13PyComposition__set_impl;
struct __pyx_opt_args_7brainpy_2_c_11composition_13PyComposition_pop;

/* "brainpy/_c/composition.pxd":10
 * cdef double PROTON = nist_mass["H+"][0][0]
 * 
 * cdef double neutral_mass(double mz,  int z, double charge_carrier=*) nogil             # <<<<<<<<<<<<<<
 * cdef double mass_charge_ratio(double neutral_mass, int z, double charge_carrier=*) nogil
 * cdef char* _parse_isotope_string(char* label, int* isotope_num, char* element_name) nogil
 */
struct __pyx_opt_args_7brainpy_2_c_11composition_neutral_mass {
  int __pyx_n;
  double charge_carrier;
};

/* "brainpy/_c/composition.pxd":11
 * 
 * cdef double neutral_mass(double mz,  int z, double charge_carrier=*) nogil
 * cdef double mass_charge_ratio(double neutral_mass, int z, double charge_carrier=*) nogil             # <<<<<<<<<<<<<<
 * cdef char* _parse_isotope_string(char* label, int* isotope_num, char* element_name) nogil
 * 
 */
struct __pyx_opt_args_7brainpy_2_c_11composition_mass_charge_ratio {
  int __pyx_n;
  double charge_carrier;
};

/* "brainpy/_c/composition.pxd":17
 * # Isotope and IsotopeMap Declarations
 * 
 * cdef struct Isotope:             # <<<<<<<<<<<<<<
 *     double mass
 *     double abundance
 */
struct __pyx_t_7brainpy_2_c_11composition_Isotope {
  double mass;
  double abundance;
  int neutrons;
  int neutron_shift;
};

/* "brainpy/_c/composition.pxd":23
 *     int neutron_shift
 * 
 * cdef struct IsotopeMap:             # <<<<<<<<<<<<<<
 *     Isotope* bins
 *     size_t size
 */
struct __pyx_t_7brainpy_2_c_11composition_IsotopeMap {
  struct __pyx_t_7brainpy_2_c_11composition_Isotope *bins;
  size_t size;
};

/* "brainpy/_c/composition.pxd":36
 * # Element Declarations
 * 
 * cdef struct Element:             # <<<<<<<<<<<<<<
 *     char* symbol
 *     IsotopeMap* isotopes
 */
struct __pyx_t_7brainpy_2_c_11composition_Element {
  char *symbol;
  struct __pyx_t_7brainpy_2_c_11composition_IsotopeMap *isotopes;
  int monoisotopic_isotope_index;
};

/* "brainpy/_c/composition.pxd":56
 * # ElementHashTable and ElementHashBucket Declarations
 * 
 * cdef struct ElementHashBucket:             # <<<<<<<<<<<<<<
 *     Element** elements
 *     size_t used
 */
struct __pyx_t_7brainpy_2_c_11composition_ElementHashBucket {
  struct __pyx_t_7brainpy_2_c_11composition_Element **elements;
  size_t used;
  size_t size;
};

/* "brainpy/_c/composition.pxd":65
 * 
 * 
 * cdef struct ElementHashTable:             # <<<<<<<<<<<<<<
 *     ElementHashBucket* buckets
 *     size_t size
 */
struct __pyx_t_7brainpy_2_c_11composition_ElementHashTable {
  struct __pyx_t_7brainpy_2_c_11composition_ElementHashBucket *buckets;
  size_t size;
};

/* "brainpy/_c/composition.pxd":94
 * # Composition Declarations
 * 
 * cdef struct Composition:             # <<<<<<<<<<<<<<
 *     char** elements
 *     count_type* counts
 */
struct __pyx_t_7brainpy_2_c_11composition_Composition {
  char **elements;
  __pyx_t_7brainpy_2_c_11composition_count_type *counts;
  size_t size;
  size_t used;
  int max_variants;
};

/* "brainpy/_c/composition.pxd":130
 *     @staticmethod
 *     cdef PyComposition _create(Composition* base)
 *     cdef void _set_impl(self, Composition* composition, bint free_existing=*)             # <<<<<<<<<<<<<<
 * 
 *     cdef void _initialize_from_formula(self, str formula)
 */
struct __pyx_opt_args_7brainpy_2_c_11composition_13PyComposition__set_impl {
  int __pyx_n;
  int free_existing;
};

/* "brainpy/_c/composition.pxd":144
 *     cpdef list items(self)
 * 
 *     cpdef pop(self, str key, object default=*)             # <<<<<<<<<<<<<<
 * 
 *     cdef count_type getitem(self, str key)
 */
struct __pyx_opt_args_7brainpy_2_c_11composition_13PyComposition_pop {
  int __pyx_n;
  PyObject *__pyx_default;
};
struct __pyx_t_7brainpy_2_c_13double_vector_DoubleVector;

/* "brainpy/_c/double_vector.pxd":1
 * cdef struct DoubleVector:             # <<<<<<<<<<<<<<
 *     double* v
 *     size_t used
 */
struct __pyx_t_7brainpy_2_c_13double_vector_DoubleVector {
  double *v;
  size_t used;
  size_t size;
};
struct __pyx_t_7brainpy_2_c_18isotopic_constants_PolynomialParameters;
struct __pyx_t_7brainpy_2_c_18isotopic_constants_PhiConstants;
struct __pyx_t_7brainpy_2_c_18isotopic_constants_IsotopicConstants;

/* "brainpy/_c/isotopic_constants.pxd":6
 * from brainpy._c.double_vector cimport DoubleVector
 * 
 * ctypedef DoubleVector dvec             # <<<<<<<<<<<<<<
 * 
 * 
 */
typedef struct __pyx_t_7brainpy_2_c_13double_vector_DoubleVector __pyx_t_7brainpy_2_c_18isotopic_constants_dvec;

/* "brainpy/_c/isotopic_constants.pxd":9
 * 
 * 
 * cdef struct PolynomialParameters:             # <<<<<<<<<<<<<<
 *     dvec* elementary_symmetric_polynomial
 *     dvec* power_sum
 */
struct __pyx_t_7brainpy_2_c_18isotopic_constants_PolynomialParameters {
  __pyx_t_7brainpy_2_c_18isotopic_constants_dvec *elementary_symmetric_polynomial;
  __pyx_t_7brainpy_2_c_18isotopic_constants_dvec *power_sum;
};

/* "brainpy/_c/isotopic_constants.pxd":14
 * 
 * 
 * cdef struct PhiConstants:             # <<<<<<<<<<<<<<
 *     int order
 *     Element* element
 */
struct __pyx_t_7brainpy_2_c_18isotopic_constants_PhiConstants {
  int order;
  struct __pyx_t_7brainpy_2_c_11composition_Element *element;
  struct __pyx_t_7brainpy_2_c_18isotopic_constants_PolynomialParameters *element_coefficients;
  struct __pyx_t_7brainpy_2_c_18isotopic_constants_PolynomialParameters *mass_coefficients;
};

/* "brainpy/_c/isotopic_constants.pxd":21
 * 
 * 
 * cdef struct IsotopicConstants:             # <<<<<<<<<<<<<<
 *     int order
 *     PhiConstants** constants
 */
struct __pyx_t_7brainpy_2_c_18isotopic_constants_IsotopicConstants {
  int order;
  struct __pyx_t_7brainpy_2_c_18isotopic_constants_PhiConstants **constants;
  size_t size;
  size_t used;
};
struct __pyx_t_7brainpy_2_c_21isotopic_distribution_Peak;
struct __pyx_t_7brainpy_2_c_21isotopic_distribution_PeakList;
struct __pyx_t_7brainpy_2_c_21isotopic_distribution_ElementCache;
struct __pyx_t_7brainpy_2_c_21isotopic_distribution_IsotopicDistribution;
struct __pyx_opt_args_7brainpy_2_c_21isotopic_distribution_make_isotopic_distribution;
struct __pyx_opt_args_7brainpy_2_c_21isotopic_distribution_guess_npeaks;
struct __pyx_opt_args_7brainpy_2_c_21isotopic_distribution__isotopic_variants;
struct __pyx_opt_args_7brainpy_2_c_21isotopic_distribution_isotopic_variants;

/* "brainpy/_c/isotopic_distribution.pxd":7
 * 
 * 
 * cdef struct Peak:             # <<<<<<<<<<<<<<
 *     double mz
 *     double intensity
 */
struct __pyx_t_7brainpy_2_c_21isotopic_distribution_Peak {
  double mz;
  double intensity;
  int charge;
};

/* "brainpy/_c/isotopic_distribution.pxd":13
 * 
 * 
 * cdef struct PeakList:             # <<<<<<<<<<<<<<
 *     Peak* peaks
 *     size_t used
 */
struct __pyx_t_7brainpy_2_c_21isotopic_distribution_PeakList {
  struct __pyx_t_7brainpy_2_c_21isotopic_distribution_Peak *peaks;
  size_t used;
  size_t size;
};

/* "brainpy/_c/isotopic_distribution.pxd":35
 * 
 * 
 * cdef struct ElementCache:             # <<<<<<<<<<<<<<
 *     Element** elements
 *     size_t used
 */
struct __pyx_t_7brainpy_2_c_21isotopic_distribution_ElementCache {
  struct __pyx_t_7brainpy_2_c_11composition_Element **elements;
  size_t used;
  size_t size;
  struct __pyx_t_7brainpy_2_c_11composition_ElementHashTable *source;
};

/* "brainpy/_c/isotopic_distribution.pxd":49
 * 
 * 
 * cdef struct IsotopicDistribution:             # <<<<<<<<<<<<<<
 *     Composition* composition
 *     IsotopicConstants* _isotopic_constants
 */
struct __pyx_t_7brainpy_2_c_21isotopic_distribution_IsotopicDistribution {
  struct __pyx_t_7brainpy_2_c_11composition_Composition *composition;
  struct __pyx_t_7brainpy_2_c_18isotopic_constants_IsotopicConstants *_isotopic_constants;
  int order;
  double average_mass;
  struct __pyx_t_7brainpy_2_c_21isotopic_distribution_Peak *monoisotopic_peak;
  struct __pyx_t_7brainpy_2_c_21isotopic_distribution_ElementCache *cache;
};

/* "brainpy/_c/isotopic_distribution.pxd":58
 * 
 * 
 * cdef IsotopicDistribution* make_isotopic_distribution(Composition* composition, int order, ElementCache* cache=*) nogil             # <<<<<<<<<<<<<<
 * cdef void free_isotopic_distribution(IsotopicDistribution* distribution)  nogil
 * 
 */
struct __pyx_opt_args_7brainpy_2_c_21isotopic_distribution_make_isotopic_distribution {
  int __pyx_n;
  struct __pyx_t_7brainpy_2_c_21isotopic_distribution_ElementCache *cache;
};

/* "brainpy/_c/isotopic_distribution.pxd":77
 * 
 * cdef int max_variants(Composition* composition, ElementCache* cache) nogil
 * cdef int guess_npeaks(Composition* composition_struct, size_t max_npeaks, ElementCache* cache=*) nogil             # <<<<<<<<<<<<<<
 * 
 * cpdef list _isotopic_variants(object composition, object npeaks=*, int charge=*, double charge_carrier=*)
 */
struct __pyx_opt_args_7brainpy_2_c_21isotopic_distribution_guess_npeaks {
  int __pyx_n;
  struct __pyx_t_7brainpy_2_c_21isotopic_distribution_ElementCache *cache;
};

/* "brainpy/_c/isotopic_distribution.pxd":79
 * cdef int guess_npeaks(Composition* composition_struct, size_t max_npeaks, ElementCache* cache=*) nogil
 * 
 * cpdef list _isotopic_variants(object composition, object npeaks=*, int charge=*, double charge_carrier=*)             # <<<<<<<<<<<<<<
 * 
 * 
 */
struct __pyx_opt_args_7brainpy_2_c_21isotopic_distribution__isotopic_variants {
  int __pyx_n;
  PyObject *npeaks;
  int charge;
  double charge_carrier;
};

/* "brainpy/_c/isotopic_distribution.pxd":82
 * 
 * 
 * cdef PeakList* isotopic_variants(Composition* composition, int npeaks, int charge=*, double charge_carrier=*) nogil             # <<<<<<<<<<<<<<
 */
struct __pyx_opt_args_7brainpy_2_c_21isotopic_distribution_isotopic_variants {
  int __pyx_n;
  int charge;
  double charge_carrier;
};
struct __pyx_opt_args_14ms_peak_picker_2_c_8peak_set_7PeakSet__has_peak;
struct __pyx_opt_args_14ms_peak_picker_2_c_8peak_set_7PeakSet_all_peaks_for;
struct __pyx_t_14ms_peak_picker_2_c_8peak_set_index_cell;
struct __pyx_t_14ms_peak_picker_2_c_8peak_set_index_list;
struct __pyx_opt_args_14ms_peak_picker_2_c_8peak_set_14PeakSetIndexed_has_peak_hinted;

/* "ms_peak_picker/_c/peak_set.pxd":42
 *     cdef FittedPeak _get_nearest_peak(self, double mz, double* errout)
 * 
 *     cdef FittedPeak _has_peak(self, double mz, double tolerance=*)             # <<<<<<<<<<<<<<
 * 
 *     cpdef PeakSet clone(self)
 */
struct __pyx_opt_args_14ms_peak_picker_2_c_8peak_set_7PeakSet__has_peak {
  int __pyx_n;
  double tolerance;
};

/* "ms_peak_picker/_c/peak_set.pxd":50
 *     cdef int _between_bounds(self, double m1, double m2, size_t* startp, size_t* endp)
 * 
 *     cpdef tuple all_peaks_for(self, double mz, double error_tolerance=*)             # <<<<<<<<<<<<<<
 * 
 *     cdef FittedPeak getitem(self, size_t i)
 */
struct __pyx_opt_args_14ms_peak_picker_2_c_8peak_set_7PeakSet_all_peaks_for {
  int __pyx_n;
  double error_tolerance;
};

/* "ms_peak_picker/_c/peak_set.pxd":64
 * 
 * 
 * cdef struct index_cell:             # <<<<<<<<<<<<<<
 *     double center_value
 *     size_t start
 */
struct __pyx_t_14ms_peak_picker_2_c_8peak_set_index_cell {
  double center_value;
  size_t start;
  size_t end;
};

/* "ms_peak_picker/_c/peak_set.pxd":70
 * 
 * 
 * cdef struct index_list:             # <<<<<<<<<<<<<<
 *     index_cell* index
 *     size_t size
 */
struct __pyx_t_14ms_peak_picker_2_c_8peak_set_index_list {
  struct __pyx_t_14ms_peak_picker_2_c_8peak_set_index_cell *index;
  size_t size;
  double low;
  double high;
};

/* "ms_peak_picker/_c/peak_set.pxd":90
 *     cpdef _allocate_index(self, size_t interval_index_size)
 * 
 *     cpdef FittedPeak has_peak_hinted(self, double mz, double tolerance=*, size_t hint_start=*, size_t hint_end=*)             # <<<<<<<<<<<<<<
 * 
 * cdef size_t double_binary_search_ppm(double* array, double value, double tolerance, size_t n)
 */
struct __pyx_opt_args_14ms_peak_picker_2_c_8peak_set_14PeakSetIndexed_has_peak_hinted {
  int __pyx_n;
  double tolerance;
  size_t hint_start;
  size_t hint_end;
};

/* "../../../../../tmp/pip-build-env-aps34_7m/overlay/lib/python3.9/site-packages/numpy/__init__.pxd":728
 * ctypedef npy_longdouble longdouble_t
 * 
 * ctypedef npy_cfloat      cfloat_t             # <<<<<<<<<<<<<<
 * ctypedef npy_cdouble     cdouble_t
 * ctypedef npy_clongdouble clongdouble_t
 */
typedef npy_cfloat __pyx_t_5numpy_cfloat_t;

/* "../../../../../tmp/pip-build-env-aps34_7m/overlay/lib/python3.9/site-packages/numpy/__init__.pxd":729
 * 
 * ctypedef npy_cfloat      cfloat_t
 * ctypedef npy_cdouble     cdouble_t             # <<<<<<<<<<<<<<
 * ctypedef npy_clongdouble clongdouble_t
 * 
 */
typedef npy_cdouble __pyx_t_5numpy_cdouble_t;

/* "../../../../../tmp/pip-build-env-aps34_7m/overlay/lib/python3.9/site-packages/numpy/__init__.pxd":730
 * ctypedef npy_cfloat      cfloat_t
 * ctypedef npy_cdouble     cdouble_t
 * ctypedef npy_clongdouble clongdouble_t             # <<<<<<<<<<<<<<
 * 
 * ctypedef npy_cdouble     complex_t
 */
typedef npy_clongdouble __pyx_t_5numpy_clongdouble_t;

/* "../../../../../tmp/pip-build-env-aps34_7m/overlay/lib/python3.9/site-packages/numpy/__init__.pxd":732
 * ctypedef npy_clongdouble clongdouble_t
 * 
 * ctypedef npy_cdouble     complex_t             # <<<<<<<<<<<<<<
 * 
 * cdef inline object PyArray_MultiIterNew1(a):
 */
typedef npy_cdouble __pyx_t_5numpy_complex_t;
struct __pyx_opt_args_14ms_peak_picker_2_c_10peak_index_9PeakIndex__has_peak;
struct __pyx_opt_args_14ms_peak_picker_2_c_10peak_index_9PeakIndex_all_peaks_for;

/* "ms_peak_picker/_c/peak_index.pxd":11
 *         public PeakSet peaks
 * 
 *     cdef FittedPeak _has_peak(self, double mz, double tolerance=*)             # <<<<<<<<<<<<<<
 *     cdef PeakSet _between(self, double start, double stop)
 * 
 */
struct __pyx_opt_args_14ms_peak_picker_2_c_10peak_index_9PeakIndex__has_peak {
  int __pyx_n;
  double tolerance;
};

/* "ms_peak_picker/_c/peak_index.pxd":14
 *     cdef PeakSet _between(self, double start, double stop)
 * 
 *     cpdef tuple all_peaks_for(self, double mz, double error_tolerance=*)             # <<<<<<<<<<<<<<
 * 
 *     cdef size_t get_size(self)
 */
struct __pyx_opt_args_14ms_peak_picker_2_c_10peak_index_9PeakIndex_all_peaks_for {
  int __pyx_n;
  double error_tolerance;
};
struct __pyx_opt_args_12ms_deisotope_2_c_9averagine_mass_charge_ratio;
struct __pyx_opt_args_12ms_deisotope_2_c_9averagine_neutral_mass;
struct __pyx_opt_args_12ms_deisotope_2_c_9averagine_9Averagine_scale;
struct __pyx_opt_args_12ms_deisotope_2_c_9averagine_9Averagine_isotopic_cluster;
struct __pyx_opt_args_12ms_deisotope_2_c_9averagine_9Averagine__isotopic_cluster;
struct __pyx_opt_args_12ms_deisotope_2_c_9averagine_26TheoreticalIsotopicPattern_ignore_below;
struct __pyx_opt_args_12ms_deisotope_2_c_9averagine_26TheoreticalIsotopicPattern_truncate_after;
struct __pyx_opt_args_12ms_deisotope_2_c_9averagine_26TheoreticalIsotopicPattern_scale;
struct __pyx_opt_args_12ms_deisotope_2_c_9averagine_26TheoreticalIsotopicPattern__scale;
struct __pyx_opt_args_12ms_deisotope_2_c_9averagine_14AveragineCache_has_mz_charge_pair;
struct __pyx_opt_args_12ms_deisotope_2_c_9averagine_14AveragineCache_isotopic_cluster;
struct __pyx_opt_args_12ms_deisotope_2_c_9averagine_isotopic_shift;

/* "ms_deisotope/_c/averagine.pxd":7
 * cdef double PROTON
 * 
 * cdef double mass_charge_ratio(double neutral_mass, int z, double charge_carrier=*)             # <<<<<<<<<<<<<<
 * cdef double neutral_mass(double mz,  int z, double charge_carrier=*)
 * cdef void slide(double mz, list peaklist)
 */
struct __pyx_opt_args_12ms_deisotope_2_c_9averagine_mass_charge_ratio {
  int __pyx_n;
  double charge_carrier;
};

/* "ms_deisotope/_c/averagine.pxd":8
 * 
 * cdef double mass_charge_ratio(double neutral_mass, int z, double charge_carrier=*)
 * cdef double neutral_mass(double mz,  int z, double charge_carrier=*)             # <<<<<<<<<<<<<<
 * cdef void slide(double mz, list peaklist)
 * cdef dict scale_dict(dict data, double factor)
 */
struct __pyx_opt_args_12ms_deisotope_2_c_9averagine_neutral_mass {
  int __pyx_n;
  double charge_carrier;
};

/* "ms_deisotope/_c/averagine.pxd":17
 *         public dict base_composition
 * 
 *     cpdef dict scale(self, double mz, int charge=*, double charge_carrier=*)             # <<<<<<<<<<<<<<
 *     cpdef TheoreticalIsotopicPattern isotopic_cluster(self, double mz, int charge=*, double charge_carrier=*, double truncate_after=*, double ignore_below=*)
 *     cdef TheoreticalIsotopicPattern _isotopic_cluster(self, double mz, int charge=*, double charge_carrier=*, double truncate_after=*, double ignore_below=*)
 */
struct __pyx_opt_args_12ms_deisotope_2_c_9averagine_9Averagine_scale {
  int __pyx_n;
  int charge;
  double charge_carrier;
};

/* "ms_deisotope/_c/averagine.pxd":18
 * 
 *     cpdef dict scale(self, double mz, int charge=*, double charge_carrier=*)
 *     cpdef TheoreticalIsotopicPattern isotopic_cluster(self, double mz, int charge=*, double charge_carrier=*, double truncate_after=*, double ignore_below=*)             # <<<<<<<<<<<<<<
 *     cdef TheoreticalIsotopicPattern _isotopic_cluster(self, double mz, int charge=*, double charge_carrier=*, double truncate_after=*, double ignore_below=*)
 * 
 */
struct __pyx_opt_args_12ms_deisotope_2_c_9averagine_9Averagine_isotopic_cluster {
  int __pyx_n;
  int charge;
  double charge_carrier;
  double truncate_after;
  double ignore_below;
};

/* "ms_deisotope/_c/averagine.pxd":19
 *     cpdef dict scale(self, double mz, int charge=*, double charge_carrier=*)
 *     cpdef TheoreticalIsotopicPattern isotopic_cluster(self, double mz, int charge=*, double charge_carrier=*, double truncate_after=*, double ignore_below=*)
 *     cdef TheoreticalIsotopicPattern _isotopic_cluster(self, double mz, int charge=*, double charge_carrier=*, double truncate_after=*, double ignore_below=*)             # <<<<<<<<<<<<<<
 * 
 * 
 */
struct __pyx_opt_args_12ms_deisotope_2_c_9averagine_9Averagine__isotopic_cluster {
  int __pyx_n;
  int charge;
  double charge_carrier;
  double truncate_after;
  double ignore_below;
};

/* "ms_deisotope/_c/averagine.pxd":39
 *     cdef bint _eq_inst(self, TheoreticalIsotopicPattern other)
 * 
 *     cpdef TheoreticalIsotopicPattern ignore_below(self, double ignore_below=*)             # <<<<<<<<<<<<<<
 *     cpdef TheoreticalIsotopicPattern truncate_after(self, double truncate_after=*)
 *     cpdef TheoreticalIsotopicPattern shift(self, double mz)
 */
struct __pyx_opt_args_12ms_deisotope_2_c_9averagine_26TheoreticalIsotopicPattern_ignore_below {
  int __pyx_n;
  double ignore_below;
};

/* "ms_deisotope/_c/averagine.pxd":40
 * 
 *     cpdef TheoreticalIsotopicPattern ignore_below(self, double ignore_below=*)
 *     cpdef TheoreticalIsotopicPattern truncate_after(self, double truncate_after=*)             # <<<<<<<<<<<<<<
 *     cpdef TheoreticalIsotopicPattern shift(self, double mz)
 *     cpdef TheoreticalIsotopicPattern scale(self, list experimental_distribution, str method=*)
 */
struct __pyx_opt_args_12ms_deisotope_2_c_9averagine_26TheoreticalIsotopicPattern_truncate_after {
  int __pyx_n;
  double truncate_after;
};

/* "ms_deisotope/_c/averagine.pxd":42
 *     cpdef TheoreticalIsotopicPattern truncate_after(self, double truncate_after=*)
 *     cpdef TheoreticalIsotopicPattern shift(self, double mz)
 *     cpdef TheoreticalIsotopicPattern scale(self, list experimental_distribution, str method=*)             # <<<<<<<<<<<<<<
 *     cpdef TheoreticalIsotopicPattern scale_raw(self, double scale_factor)
 *     cpdef double drop_last_peak(self)
 */
struct __pyx_opt_args_12ms_deisotope_2_c_9averagine_26TheoreticalIsotopicPattern_scale {
  int __pyx_n;
  PyObject *method;
};

/* "ms_deisotope/_c/averagine.pxd":53
 * 
 *     @cython.final
 *     cdef inline TheoreticalIsotopicPattern _scale(self, list experimental_distribution, str method=*)             # <<<<<<<<<<<<<<
 * 
 *     @cython.final
 */
struct __pyx_opt_args_12ms_deisotope_2_c_9averagine_26TheoreticalIsotopicPattern__scale {
  int __pyx_n;
  PyObject *method;
};

/* "ms_deisotope/_c/averagine.pxd":88
 *     cdef double _make_cache_key(self, double mz)
 * 
 *     cdef TheoreticalIsotopicPattern has_mz_charge_pair(self, double mz, int charge=*, double charge_carrier=*, double truncate_after=*, double ignore_below=*)             # <<<<<<<<<<<<<<
 *     cpdef TheoreticalIsotopicPattern isotopic_cluster(self, double mz, int charge=*, double charge_carrier=*, double truncate_after=*, double ignore_below=*)
 * 
 */
struct __pyx_opt_args_12ms_deisotope_2_c_9averagine_14AveragineCache_has_mz_charge_pair {
  int __pyx_n;
  int charge;
  double charge_carrier;
  double truncate_after;
  double ignore_below;
};

/* "ms_deisotope/_c/averagine.pxd":89
 * 
 *     cdef TheoreticalIsotopicPattern has_mz_charge_pair(self, double mz, int charge=*, double charge_carrier=*, double truncate_after=*, double ignore_below=*)
 *     cpdef TheoreticalIsotopicPattern isotopic_cluster(self, double mz, int charge=*, double charge_carrier=*, double truncate_after=*, double ignore_below=*)             # <<<<<<<<<<<<<<
 * 
 * 
 */
struct __pyx_opt_args_12ms_deisotope_2_c_9averagine_14AveragineCache_isotopic_cluster {
  int __pyx_n;
  int charge;
  double charge_carrier;
  double truncate_after;
  double ignore_below;
};

/* "ms_deisotope/_c/averagine.pxd":92
 * 
 * 
 * cpdef double isotopic_shift(int charge=*)             # <<<<<<<<<<<<<<
 */
struct __pyx_opt_args_12ms_deisotope_2_c_9averagine_isotopic_shift {
  int __pyx_n;
  int charge;
};
struct __pyx_opt_args_12ms_deisotope_2_c_17deconvoluter_base_16DeconvoluterBase_match_theoretical_isotopic_distribution;
struct __pyx_opt_args_12ms_deisotope_2_c_17deconvoluter_base_16DeconvoluterBase_subtraction;
struct __pyx_opt_args_12ms_deisotope_2_c_17deconvoluter_base_16DeconvoluterBase__find_next_putative_peak;
struct __pyx_opt_args_12ms_deisotope_2_c_17deconvoluter_base_16DeconvoluterBase__find_previous_putative_peak;
struct __pyx_opt_args_12ms_deisotope_2_c_17deconvoluter_base_16DeconvoluterBase__find_next_putative_peak_inplace;
struct __pyx_opt_args_12ms_deisotope_2_c_17deconvoluter_base_16DeconvoluterBase__find_previous_putative_peak_inplace;
struct __pyx_opt_args_12ms_deisotope_2_c_17deconvoluter_base_25AveragineDeconvoluterBase_fit_theoretical_distribution;
struct __pyx_opt_args_12ms_deisotope_2_c_17deconvoluter_base_25AveragineDeconvoluterBase__fit_peaks_at_charges;
struct __pyx_opt_args_12ms_deisotope_2_c_17deconvoluter_base_30MultiAveragineDeconvoluterBase_fit_theoretical_distribution;
struct __pyx_opt_args_12ms_deisotope_2_c_17deconvoluter_base_30MultiAveragineDeconvoluterBase__fit_peaks_at_charges;
struct __pyx_opt_args_12ms_deisotope_2_c_17deconvoluter_base__get_all_peak_charge_pairs;

/* "ms_deisotope/_c/deconvoluter_base.pxd":42
 *     cdef FittedPeak _has_peak(self, double mz, double error_tolerance)
 * 
 *     cpdef list match_theoretical_isotopic_distribution(self, list theoretical_distribution, double error_tolerance=*)             # <<<<<<<<<<<<<<
 *     cpdef scale_theoretical_distribution(self, TheoreticalIsotopicPattern theoretical_distribution, list experimental_distribution)
 *     cpdef IsotopicFitRecord _evaluate_theoretical_distribution(self, list experimental, TheoreticalIsotopicPattern theoretical, FittedPeak peak, int charge)
 */
struct __pyx_opt_args_12ms_deisotope_2_c_17deconvoluter_base_16DeconvoluterBase_match_theoretical_isotopic_distribution {
  int __pyx_n;
  double error_tolerance;
};

/* "ms_deisotope/_c/deconvoluter_base.pxd":45
 *     cpdef scale_theoretical_distribution(self, TheoreticalIsotopicPattern theoretical_distribution, list experimental_distribution)
 *     cpdef IsotopicFitRecord _evaluate_theoretical_distribution(self, list experimental, TheoreticalIsotopicPattern theoretical, FittedPeak peak, int charge)
 *     cpdef subtraction(self, TheoreticalIsotopicPattern isotopic_cluster, double error_tolerance=*)             # <<<<<<<<<<<<<<
 *     cpdef list fit_incremental_truncation(self, IsotopicFitRecord seed_fit, double lower_bound)
 * 
 */
struct __pyx_opt_args_12ms_deisotope_2_c_17deconvoluter_base_16DeconvoluterBase_subtraction {
  int __pyx_n;
  double error_tolerance;
};

/* "ms_deisotope/_c/deconvoluter_base.pxd":50
 *     cpdef bint _check_fit(self, IsotopicFitRecord fit)
 * 
 *     cpdef list _find_next_putative_peak(self, double mz, int charge, int step=*, double tolerance=*)             # <<<<<<<<<<<<<<
 *     cpdef list _find_previous_putative_peak(self, double mz, int charge, int step=*, double tolerance=*)
 * 
 */
struct __pyx_opt_args_12ms_deisotope_2_c_17deconvoluter_base_16DeconvoluterBase__find_next_putative_peak {
  int __pyx_n;
  int step;
  double tolerance;
};

/* "ms_deisotope/_c/deconvoluter_base.pxd":51
 * 
 *     cpdef list _find_next_putative_peak(self, double mz, int charge, int step=*, double tolerance=*)
 *     cpdef list _find_previous_putative_peak(self, double mz, int charge, int step=*, double tolerance=*)             # <<<<<<<<<<<<<<
 * 
 *     cdef int _find_next_putative_peak_inplace(self, double mz, int charge, set result, int step=*, double tolerance=*)
 */
struct __pyx_opt_args_12ms_deisotope_2_c_17deconvoluter_base_16DeconvoluterBase__find_previous_putative_peak {
  int __pyx_n;
  int step;
  double tolerance;
};

/* "ms_deisotope/_c/deconvoluter_base.pxd":53
 *     cpdef list _find_previous_putative_peak(self, double mz, int charge, int step=*, double tolerance=*)
 * 
 *     cdef int _find_next_putative_peak_inplace(self, double mz, int charge, set result, int step=*, double tolerance=*)             # <<<<<<<<<<<<<<
 *     cdef int _find_previous_putative_peak_inplace(self, double mz, int charge, set result, int step=*, double tolerance=*)
 * 
 */
struct __pyx_opt_args_12ms_deisotope_2_c_17deconvoluter_base_16DeconvoluterBase__find_next_putative_peak_inplace {
  int __pyx_n;
  int step;
  double tolerance;
};

/* "ms_deisotope/_c/deconvoluter_base.pxd":54
 * 
 *     cdef int _find_next_putative_peak_inplace(self, double mz, int charge, set result, int step=*, double tolerance=*)
 *     cdef int _find_previous_putative_peak_inplace(self, double mz, int charge, set result, int step=*, double tolerance=*)             # <<<<<<<<<<<<<<
 * 
 * 
 */
struct __pyx_opt_args_12ms_deisotope_2_c_17deconvoluter_base_16DeconvoluterBase__find_previous_putative_peak_inplace {
  int __pyx_n;
  int step;
  double tolerance;
};

/* "ms_deisotope/_c/deconvoluter_base.pxd":61
 *         public AveragineCache averagine
 * 
 *     cpdef IsotopicFitRecord fit_theoretical_distribution(self, FittedPeak peak, double error_tolerance, int charge,             # <<<<<<<<<<<<<<
 *                                                          double charge_carrier=*, double truncate_after=*,
 *                                                          double ignore_below=*)
 */
struct __pyx_opt_args_12ms_deisotope_2_c_17deconvoluter_base_25AveragineDeconvoluterBase_fit_theoretical_distribution {
  int __pyx_n;
  double charge_carrier;
  double truncate_after;
  double ignore_below;
};

/* "ms_deisotope/_c/deconvoluter_base.pxd":65
 *                                                          double ignore_below=*)
 * 
 *     cpdef set _fit_peaks_at_charges(self, set peak_charge_set, double error_tolerance, double charge_carrier=*, double truncate_after=*,             # <<<<<<<<<<<<<<
 *                                     double ignore_below=*)
 * 
 */
struct __pyx_opt_args_12ms_deisotope_2_c_17deconvoluter_base_25AveragineDeconvoluterBase__fit_peaks_at_charges {
  int __pyx_n;
  double charge_carrier;
  double truncate_after;
  double ignore_below;
};

/* "ms_deisotope/_c/deconvoluter_base.pxd":73
 *         public list averagines
 * 
 *     cpdef IsotopicFitRecord fit_theoretical_distribution(self, FittedPeak peak, double error_tolerance, int charge,             # <<<<<<<<<<<<<<
 *                                                          AveragineCache  averagine, double charge_carrier=*, double truncate_after=*,
 *                                                          double ignore_below=*)
 */
struct __pyx_opt_args_12ms_deisotope_2_c_17deconvoluter_base_30MultiAveragineDeconvoluterBase_fit_theoretical_distribution {
  int __pyx_n;
  double charge_carrier;
  double truncate_after;
  double ignore_below;
};

/* "ms_deisotope/_c/deconvoluter_base.pxd":76
 *                                                          AveragineCache  averagine, double charge_carrier=*, double truncate_after=*,
 *                                                          double ignore_below=*)
 *     cpdef set _fit_peaks_at_charges(self, set peak_charge_set, double error_tolerance, double charge_carrier=*, double truncate_after=*,             # <<<<<<<<<<<<<<
 *                                     double ignore_below=*)
 * 
 */
struct __pyx_opt_args_12ms_deisotope_2_c_17deconvoluter_base_30MultiAveragineDeconvoluterBase__fit_peaks_at_charges {
  int __pyx_n;
  double charge_carrier;
  double truncate_after;
  double ignore_below;
};

/* "ms_deisotope/_c/deconvoluter_base.pxd":83
 * 
 * 
 * cpdef set _get_all_peak_charge_pairs(DeconvoluterBase self, FittedPeak peak, double error_tolerance=*,             # <<<<<<<<<<<<<<
 *                                      object charge_range=*,
 *                                      int left_search_limit=*, int right_search_limit=*,
 */
struct __pyx_opt_args_12ms_deisotope_2_c_17deconvoluter_base__get_all_peak_charge_pairs {
  int __pyx_n;
  double error_tolerance;
  PyObject *charge_range;
  int left_search_limit;
  int right_search_limit;
  int recalculate_starting_peak;
  int use_quick_charge;
};
struct __pyx_opt_args_12ms_deisotope_2_c_7scoring_17IsotopicFitRecord__create;
struct __pyx_opt_args_12ms_deisotope_2_c_7scoring_14MSDeconVFitter_score_peak;
struct __pyx_opt_args_12ms_deisotope_2_c_7scoring_21InterferenceDetection_detect_interference;

/* "ms_deisotope/_c/scoring.pxd":29
 * 
 *     @staticmethod
 *     cdef IsotopicFitRecord _create(FittedPeak seed_peak, double score, int charge, TheoreticalIsotopicPattern theoretical,             # <<<<<<<<<<<<<<
 *                                    list experimental, object data=*, int missed_peaks=*)
 * 
 */
struct __pyx_opt_args_12ms_deisotope_2_c_7scoring_17IsotopicFitRecord__create {
  int __pyx_n;
  PyObject *data;
  int missed_peaks;
};

/* "ms_deisotope/_c/scoring.pxd":75
 *     cdef public double mass_error_tolerance
 * 
 *     cdef double score_peak(self, FittedPeak obs, TheoreticalPeak theo, double mass_error_tolerance=*, double minimum_signal_to_noise=*) nogil             # <<<<<<<<<<<<<<
 * 
 * 
 */
struct __pyx_opt_args_12ms_deisotope_2_c_7scoring_14MSDeconVFitter_score_peak {
  int __pyx_n;
  double mass_error_tolerance;
  double minimum_signal_to_noise;
};

/* "ms_deisotope/_c/scoring.pxd":92
 *     cdef public PeakSet peaklist
 * 
 *     cdef double detect_interference(self, list experimental_peaks, double lower=*, double upper=*)             # <<<<<<<<<<<<<<
 * 
 * 
 */
struct __pyx_opt_args_12ms_deisotope_2_c_7scoring_21InterferenceDetection_detect_interference {
  int __pyx_n;
  double lower;
  double upper;
};
struct __pyx_opt_args_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_17ConnectedSubgraph_find_heaviest_path;
struct __pyx_opt_args_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_layout_layers;

/* "ms_deisotope/_c/peak_dependency_network/subgraph.pxd":35
 *     cdef void _init_nodes(self, list fits)
 *     cdef void populate_edges(self)
 *     cpdef find_heaviest_path(self, method=*)             # <<<<<<<<<<<<<<
 */
struct __pyx_opt_args_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_17ConnectedSubgraph_find_heaviest_path {
  int __pyx_n;
  PyObject *method;
};

/* "ms_deisotope/_c/peak_dependency_network/subgraph.pyx":96
 * 
 * @cython.nonecheck(False)
 * cpdef list layout_layers(list envelopes, bint maximize=True):             # <<<<<<<<<<<<<<
 *     '''
 *     Produce a non-overlapping stacked layout of individual envelopes.
 */
struct __pyx_opt_args_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_layout_layers {
  int __pyx_n;
  int maximize;
};

/* "ms_deisotope/_c/peak_dependency_network/intervals.pxd":1
 * cdef class SpanningMixin(object):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public double start
 */
struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_9intervals_SpanningMixin {
  PyObject_HEAD
  struct __pyx_vtabstruct_12ms_deisotope_2_c_23peak_dependency_network_9intervals_SpanningMixin *__pyx_vtab;
  double start;
  double end;
};


/* "ms_deisotope/_c/peak_dependency_network/intervals.pxd":19
 * 
 * 
 * cdef class Interval(SpanningMixin):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public object members
 */
struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_9intervals_Interval {
  struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_9intervals_SpanningMixin __pyx_base;
  PyObject *members;
  PyObject *data;
};


/* "ms_deisotope/_c/peak_dependency_network/intervals.pxd":25
 * 
 * 
 * cdef class IntervalTreeNode(object):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public double center
 */
struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_9intervals_IntervalTreeNode {
  PyObject_HEAD
  struct __pyx_vtabstruct_12ms_deisotope_2_c_23peak_dependency_network_9intervals_IntervalTreeNode *__pyx_vtab;
  double center;
  double start;
  double end;
  struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_9intervals_IntervalTreeNode *left;
  struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_9intervals_IntervalTreeNode *right;
  PyObject *contained;
  int level;
  struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_9intervals_IntervalTreeNode *parent;
};


/* "brainpy/_c/composition.pxd":123
 * 
 * 
 * cdef class PyComposition(object):             # <<<<<<<<<<<<<<
 *     cdef:
 *         Composition* impl
 */
struct __pyx_obj_7brainpy_2_c_11composition_PyComposition {
  PyObject_HEAD
  struct __pyx_vtabstruct_7brainpy_2_c_11composition_PyComposition *__pyx_vtab;
  struct __pyx_t_7brainpy_2_c_11composition_Composition *impl;
  double cached_mass;
  int _clean;
};


/* "brainpy/_c/isotopic_distribution.pxd":63
 * 
 * @freelist(100000)
 * cdef class TheoreticalPeak(object):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public double mz
 */
struct __pyx_obj_7brainpy_2_c_21isotopic_distribution_TheoreticalPeak {
  PyObject_HEAD
  struct __pyx_vtabstruct_7brainpy_2_c_21isotopic_distribution_TheoreticalPeak *__pyx_vtab;
  double mz;
  double intensity;
  int charge;
};


/* "ms_peak_picker/_c/peak_set.pxd":2
 * 
 * cdef class PeakBase(object):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public double mz
 */
struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakBase {
  PyObject_HEAD
  struct __pyx_vtabstruct_14ms_peak_picker_2_c_8peak_set_PeakBase *__pyx_vtab;
  double mz;
  double intensity;
  double area;
};


/* "ms_peak_picker/_c/peak_set.pxd":12
 * 
 * 
 * cdef class FittedPeak(PeakBase):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public double signal_to_noise
 */
struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_FittedPeak {
  struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakBase __pyx_base;
  double signal_to_noise;
  double full_width_at_half_max;
  double left_width;
  double right_width;
  long peak_count;
  long index;
};


/* "ms_peak_picker/_c/peak_set.pxd":29
 *                             double area)
 * 
 * cdef class PeakSet(object):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public tuple peaks
 */
struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSet {
  PyObject_HEAD
  struct __pyx_vtabstruct_14ms_peak_picker_2_c_8peak_set_PeakSet *__pyx_vtab;
  PyObject *peaks;
  int indexed;
};


/* "ms_peak_picker/_c/peak_set.pxd":83
 * 
 * 
 * cdef class PeakSetIndexed(PeakSet):             # <<<<<<<<<<<<<<
 *     cdef:
 *         double* mz_index
 */
struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSetIndexed {
  struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSet __pyx_base;
  double *mz_index;
  struct __pyx_t_14ms_peak_picker_2_c_8peak_set_index_list *interval_index;
};


/* "ms_peak_picker/_c/peak_index.pxd":5
 * 
 * 
 * cdef class PeakIndex(object):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public np.ndarray mz_array
 */
struct __pyx_obj_14ms_peak_picker_2_c_10peak_index_PeakIndex {
  PyObject_HEAD
  struct __pyx_vtabstruct_14ms_peak_picker_2_c_10peak_index_PeakIndex *__pyx_vtab;
  PyArrayObject *mz_array;
  PyArrayObject *intensity_array;
  struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSet *peaks;
};


/* "ms_deisotope/_c/averagine.pxd":12
 * cdef dict scale_dict(dict data, double factor)
 * 
 * cdef class Averagine(object):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public double base_mass
 */
struct __pyx_obj_12ms_deisotope_2_c_9averagine_Averagine {
  PyObject_HEAD
  struct __pyx_vtabstruct_12ms_deisotope_2_c_9averagine_Averagine *__pyx_vtab;
  double base_mass;
  PyObject *base_composition;
};


/* "ms_deisotope/_c/averagine.pxd":23
 * 
 * @cython.final
 * cdef class TheoreticalIsotopicPattern(object):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public list peaklist
 */
struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern {
  PyObject_HEAD
  struct __pyx_vtabstruct_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *__pyx_vtab;
  PyObject *peaklist;
  double origin;
  double offset;
};


/* "ms_deisotope/_c/averagine.pxd":79
 * 
 * @cython.final
 * cdef class AveragineCache(object):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public dict backend
 */
struct __pyx_obj_12ms_deisotope_2_c_9averagine_AveragineCache {
  PyObject_HEAD
  struct __pyx_vtabstruct_12ms_deisotope_2_c_9averagine_AveragineCache *__pyx_vtab;
  PyObject *backend;
  struct __pyx_obj_12ms_deisotope_2_c_9averagine_Averagine *averagine;
  double cache_truncation;
  int enabled;
};


/* "ms_deisotope/_c/deconvoluter_base.pxd":25
 * 
 * 
 * cdef class DeconvoluterBase(object):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public bint use_subtraction
 */
struct __pyx_obj_12ms_deisotope_2_c_17deconvoluter_base_DeconvoluterBase {
  PyObject_HEAD
  struct __pyx_vtabstruct_12ms_deisotope_2_c_17deconvoluter_base_DeconvoluterBase *__pyx_vtab;
  int use_subtraction;
  PyObject *scale_method;
  int merge_isobaric_peaks;
  double minimum_intensity;
  struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSet *peaklist;
  struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitterBase *scorer;
  int verbose;
  PyObject *_slice_cache;
};


/* "ms_deisotope/_c/deconvoluter_base.pxd":57
 * 
 * 
 * cdef class AveragineDeconvoluterBase(DeconvoluterBase):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public AveragineCache averagine
 */
struct __pyx_obj_12ms_deisotope_2_c_17deconvoluter_base_AveragineDeconvoluterBase {
  struct __pyx_obj_12ms_deisotope_2_c_17deconvoluter_base_DeconvoluterBase __pyx_base;
  struct __pyx_obj_12ms_deisotope_2_c_9averagine_AveragineCache *averagine;
};


/* "ms_deisotope/_c/deconvoluter_base.pxd":69
 * 
 * 
 * cdef class MultiAveragineDeconvoluterBase(DeconvoluterBase):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public list averagines
 */
struct __pyx_obj_12ms_deisotope_2_c_17deconvoluter_base_MultiAveragineDeconvoluterBase {
  struct __pyx_obj_12ms_deisotope_2_c_17deconvoluter_base_DeconvoluterBase __pyx_base;
  PyObject *averagines;
};


/* "ms_deisotope/_c/deconvoluter_base.pxd":91
 * 
 * 
 * cdef class ChargeIterator(object):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public int lower
 */
struct __pyx_obj_12ms_deisotope_2_c_17deconvoluter_base_ChargeIterator {
  PyObject_HEAD
  struct __pyx_vtabstruct_12ms_deisotope_2_c_17deconvoluter_base_ChargeIterator *__pyx_vtab;
  int lower;
  int upper;
  int sign;
  int *values;
  size_t size;
  size_t index;
};


/* "ms_deisotope/_c/scoring.pxd":16
 * 
 * 
 * cdef class IsotopicFitRecord(object):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public FittedPeak seed_peak
 */
struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitRecord {
  PyObject_HEAD
  struct __pyx_vtabstruct_12ms_deisotope_2_c_7scoring_IsotopicFitRecord *__pyx_vtab;
  struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_FittedPeak *seed_peak;
  double score;
  int charge;
  PyObject *experimental;
  struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *theoretical;
  struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_FittedPeak *monoisotopic_peak;
  int missed_peaks;
  PyObject *data;
  Py_hash_t _hash;
};


/* "ms_deisotope/_c/scoring.pxd":38
 * 
 * 
 * cdef class FitSelectorBase(object):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public double minimum_score
 */
struct __pyx_obj_12ms_deisotope_2_c_7scoring_FitSelectorBase {
  PyObject_HEAD
  struct __pyx_vtabstruct_12ms_deisotope_2_c_7scoring_FitSelectorBase *__pyx_vtab;
  double minimum_score;
};


/* "ms_deisotope/_c/scoring.pxd":50
 * 
 * 
 * cdef class IsotopicFitterBase(object):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public FitSelectorBase select
 */
struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitterBase {
  PyObject_HEAD
  struct __pyx_vtabstruct_12ms_deisotope_2_c_7scoring_IsotopicFitterBase *__pyx_vtab;
  struct __pyx_obj_12ms_deisotope_2_c_7scoring_FitSelectorBase *select;
};


/* "ms_deisotope/_c/scoring.pxd":62
 * 
 * 
 * cdef class LeastSquaresFitter(IsotopicFitterBase):             # <<<<<<<<<<<<<<
 *     pass
 * 
 */
struct __pyx_obj_12ms_deisotope_2_c_7scoring_LeastSquaresFitter {
  struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitterBase __pyx_base;
};


/* "ms_deisotope/_c/scoring.pxd":66
 * 
 * 
 * cdef class GTestFitter(IsotopicFitterBase):             # <<<<<<<<<<<<<<
 *     pass
 * 
 */
struct __pyx_obj_12ms_deisotope_2_c_7scoring_GTestFitter {
  struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitterBase __pyx_base;
};


/* "ms_deisotope/_c/scoring.pxd":69
 *     pass
 * 
 * cdef class ScaledGTestFitter(IsotopicFitterBase):             # <<<<<<<<<<<<<<
 *     pass
 * 
 */
struct __pyx_obj_12ms_deisotope_2_c_7scoring_ScaledGTestFitter {
  struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitterBase __pyx_base;
};


/* "ms_deisotope/_c/scoring.pxd":72
 *     pass
 * 
 * cdef class MSDeconVFitter(IsotopicFitterBase):             # <<<<<<<<<<<<<<
 *     cdef public double mass_error_tolerance
 * 
 */
struct __pyx_obj_12ms_deisotope_2_c_7scoring_MSDeconVFitter {
  struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitterBase __pyx_base;
  double mass_error_tolerance;
};


/* "ms_deisotope/_c/scoring.pxd":78
 * 
 * 
 * cdef class PenalizedMSDeconVFitter(IsotopicFitterBase):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public double mass_error_tolerance
 */
struct __pyx_obj_12ms_deisotope_2_c_7scoring_PenalizedMSDeconVFitter {
  struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitterBase __pyx_base;
  double mass_error_tolerance;
  double penalty_factor;
};


/* "ms_deisotope/_c/scoring.pxd":84
 * 
 * 
 * cdef class FunctionScorer(IsotopicFitterBase):             # <<<<<<<<<<<<<<
 *     cdef:
 *         object function
 */
struct __pyx_obj_12ms_deisotope_2_c_7scoring_FunctionScorer {
  struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitterBase __pyx_base;
  PyObject *function;
};


/* "ms_deisotope/_c/scoring.pxd":89
 * 
 * 
 * cdef class InterferenceDetection(object):             # <<<<<<<<<<<<<<
 *     cdef public PeakSet peaklist
 * 
 */
struct __pyx_obj_12ms_deisotope_2_c_7scoring_InterferenceDetection {
  PyObject_HEAD
  struct __pyx_vtabstruct_12ms_deisotope_2_c_7scoring_InterferenceDetection *__pyx_vtab;
  struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSet *peaklist;
};


/* "ms_deisotope/_c/scoring.pxd":95
 * 
 * 
 * cdef class DistinctPatternFitter(IsotopicFitterBase):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public InterferenceDetection interference_detector
 */
struct __pyx_obj_12ms_deisotope_2_c_7scoring_DistinctPatternFitter {
  struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitterBase __pyx_base;
  struct __pyx_obj_12ms_deisotope_2_c_7scoring_InterferenceDetection *interference_detector;
  struct __pyx_obj_12ms_deisotope_2_c_7scoring_ScaledGTestFitter *g_test_scaled;
  double peak_count_scale;
  double domain_scale;
};


/* "ms_deisotope/_c/scoring.pxd":102
 *         public double domain_scale
 * 
 * cdef class ScaledPenalizedMSDeconvFitter(IsotopicFitterBase):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public double scale_factor
 */
struct __pyx_obj_12ms_deisotope_2_c_7scoring_ScaledPenalizedMSDeconvFitter {
  struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitterBase __pyx_base;
  double scale_factor;
  struct __pyx_obj_12ms_deisotope_2_c_7scoring_PenalizedMSDeconVFitter *scorer;
};


/* "ms_deisotope/_c/scoring.pxd":112
 * 
 * 
 * cdef class DotProductFitter(IsotopicFitterBase):             # <<<<<<<<<<<<<<
 *     pass
 */
struct __pyx_obj_12ms_deisotope_2_c_7scoring_DotProductFitter {
  struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitterBase __pyx_base;
};


/* "ms_deisotope/_c/peak_dependency_network/subgraph.pxd":8
 * 
 * 
 * cdef class FitNode(SpanningMixin):             # <<<<<<<<<<<<<<
 * 
 *     cdef:
 */
struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_FitNode {
  struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_9intervals_SpanningMixin __pyx_base;
  size_t index;
  struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitRecord *fit;
  PyObject *edges;
  PyObject *overlap_edges;
  PyObject *peak_indices;
  long _hash;
  double score;
};


/* "ms_deisotope/_c/peak_dependency_network/subgraph.pxd":28
 * 
 * 
 * cdef class ConnectedSubgraph(object):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public tuple nodes
 */
struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_ConnectedSubgraph {
  PyObject_HEAD
  struct __pyx_vtabstruct_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_ConnectedSubgraph *__pyx_vtab;
  PyObject *nodes;
  int maximize;
};


/* "ms_deisotope/_c/peak_dependency_network/subgraph.pyx":133
 * @cython.final
 * @cython.freelist(5)
 * cdef class GreedySubgraphSelection(object):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public list intervals
 */
struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_GreedySubgraphSelection {
  PyObject_HEAD
  struct __pyx_vtabstruct_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_GreedySubgraphSelection *__pyx_vtab;
  PyObject *intervals;
  PyObject *_layers;
  int maximize;
};



/* "ms_deisotope/_c/peak_dependency_network/intervals.pxd":1
 * cdef class SpanningMixin(object):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public double start
 */

struct __pyx_vtabstruct_12ms_deisotope_2_c_23peak_dependency_network_9intervals_SpanningMixin {
  int (*_contains)(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_9intervals_SpanningMixin *, double);
  int (*contains)(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_9intervals_SpanningMixin *, double, int __pyx_skip_dispatch);
  int (*overlaps)(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_9intervals_SpanningMixin *, struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_9intervals_SpanningMixin *, int __pyx_skip_dispatch);
  double (*overlap_size)(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_9intervals_SpanningMixin *, struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_9intervals_SpanningMixin *, int __pyx_skip_dispatch);
  int (*is_contained_in_interval)(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_9intervals_SpanningMixin *, struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_9intervals_SpanningMixin *, int __pyx_skip_dispatch);
  int (*contains_interval)(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_9intervals_SpanningMixin *, struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_9intervals_SpanningMixin *, int __pyx_skip_dispatch);
};
static struct __pyx_vtabstruct_12ms_deisotope_2_c_23peak_dependency_network_9intervals_SpanningMixin *__pyx_vtabptr_12ms_deisotope_2_c_23peak_dependency_network_9intervals_SpanningMixin;


/* "ms_deisotope/_c/peak_dependency_network/intervals.pxd":19
 * 
 * 
 * cdef class Interval(SpanningMixin):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public object members
 */

struct __pyx_vtabstruct_12ms_deisotope_2_c_23peak_dependency_network_9intervals_Interval {
  struct __pyx_vtabstruct_12ms_deisotope_2_c_23peak_dependency_network_9intervals_SpanningMixin __pyx_base;
};
static struct __pyx_vtabstruct_12ms_deisotope_2_c_23peak_dependency_network_9intervals_Interval *__pyx_vtabptr_12ms_deisotope_2_c_23peak_dependency_network_9intervals_Interval;


/* "ms_deisotope/_c/peak_dependency_network/intervals.pxd":25
 * 
 * 
 * cdef class IntervalTreeNode(object):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public double center
 */

struct __pyx_vtabstruct_12ms_deisotope_2_c_23peak_dependency_network_9intervals_IntervalTreeNode {
  PyObject *(*contains_point)(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_9intervals_IntervalTreeNode *, double, int __pyx_skip_dispatch);
  PyObject *(*_overlaps_interval)(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_9intervals_IntervalTreeNode *, double, double, int __pyx_skip_dispatch);
  PyObject *(*overlaps)(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_9intervals_IntervalTreeNode *, double, double, int __pyx_skip_dispatch);
  int (*_eq)(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_9intervals_IntervalTreeNode *, struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_9intervals_IntervalTreeNode *, int __pyx_skip_dispatch);
};
static struct __pyx_vtabstruct_12ms_deisotope_2_c_23peak_dependency_network_9intervals_IntervalTreeNode *__pyx_vtabptr_12ms_deisotope_2_c_23peak_dependency_network_9intervals_IntervalTreeNode;


/* "brainpy/_c/composition.pxd":123
 * 
 * 
 * cdef class PyComposition(object):             # <<<<<<<<<<<<<<
 *     cdef:
 *         Composition* impl
 */

struct __pyx_vtabstruct_7brainpy_2_c_11composition_PyComposition {
  struct __pyx_obj_7brainpy_2_c_11composition_PyComposition *(*_create)(struct __pyx_t_7brainpy_2_c_11composition_Composition *);
  void (*_set_impl)(struct __pyx_obj_7brainpy_2_c_11composition_PyComposition *, struct __pyx_t_7brainpy_2_c_11composition_Composition *, struct __pyx_opt_args_7brainpy_2_c_11composition_13PyComposition__set_impl *__pyx_optional_args);
  void (*_initialize_from_formula)(struct __pyx_obj_7brainpy_2_c_11composition_PyComposition *, PyObject *);
  double (*mass)(struct __pyx_obj_7brainpy_2_c_11composition_PyComposition *, int __pyx_skip_dispatch);
  int (*__pyx___equality_pycomposition)(struct __pyx_obj_7brainpy_2_c_11composition_PyComposition *, struct __pyx_obj_7brainpy_2_c_11composition_PyComposition *, int __pyx_skip_dispatch);
  int (*__pyx___equality_dict)(struct __pyx_obj_7brainpy_2_c_11composition_PyComposition *, PyObject *, int __pyx_skip_dispatch);
  struct __pyx_obj_7brainpy_2_c_11composition_PyComposition *(*copy)(struct __pyx_obj_7brainpy_2_c_11composition_PyComposition *, int __pyx_skip_dispatch);
  PyObject *(*update)(struct __pyx_obj_7brainpy_2_c_11composition_PyComposition *, PyObject *, int __pyx_skip_dispatch);
  PyObject *(*keys)(struct __pyx_obj_7brainpy_2_c_11composition_PyComposition *, int __pyx_skip_dispatch);
  PyObject *(*values)(struct __pyx_obj_7brainpy_2_c_11composition_PyComposition *, int __pyx_skip_dispatch);
  PyObject *(*items)(struct __pyx_obj_7brainpy_2_c_11composition_PyComposition *, int __pyx_skip_dispatch);
  PyObject *(*pop)(struct __pyx_obj_7brainpy_2_c_11composition_PyComposition *, PyObject *, int __pyx_skip_dispatch, struct __pyx_opt_args_7brainpy_2_c_11composition_13PyComposition_pop *__pyx_optional_args);
  __pyx_t_7brainpy_2_c_11composition_count_type (*getitem)(struct __pyx_obj_7brainpy_2_c_11composition_PyComposition *, PyObject *);
  void (*setitem)(struct __pyx_obj_7brainpy_2_c_11composition_PyComposition *, PyObject *, __pyx_t_7brainpy_2_c_11composition_count_type);
  void (*increment)(struct __pyx_obj_7brainpy_2_c_11composition_PyComposition *, PyObject *, __pyx_t_7brainpy_2_c_11composition_count_type);
  void (*add_from)(struct __pyx_obj_7brainpy_2_c_11composition_PyComposition *, struct __pyx_obj_7brainpy_2_c_11composition_PyComposition *);
  void (*subtract_from)(struct __pyx_obj_7brainpy_2_c_11composition_PyComposition *, struct __pyx_obj_7brainpy_2_c_11composition_PyComposition *);
  void (*scale_by)(struct __pyx_obj_7brainpy_2_c_11composition_PyComposition *, long);
};
static struct __pyx_vtabstruct_7brainpy_2_c_11composition_PyComposition *__pyx_vtabptr_7brainpy_2_c_11composition_PyComposition;


/* "brainpy/_c/isotopic_distribution.pxd":63
 * 
 * @freelist(100000)
 * cdef class TheoreticalPeak(object):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public double mz
 */

struct __pyx_vtabstruct_7brainpy_2_c_21isotopic_distribution_TheoreticalPeak {
  struct __pyx_obj_7brainpy_2_c_21isotopic_distribution_TheoreticalPeak *(*_create)(double, double, int);
  int (*_eq)(struct __pyx_obj_7brainpy_2_c_21isotopic_distribution_TheoreticalPeak *, struct __pyx_obj_7brainpy_2_c_21isotopic_distribution_TheoreticalPeak *, int __pyx_skip_dispatch);
  struct __pyx_obj_7brainpy_2_c_21isotopic_distribution_TheoreticalPeak *(*clone)(struct __pyx_obj_7brainpy_2_c_21isotopic_distribution_TheoreticalPeak *, int __pyx_skip_dispatch);
};
static struct __pyx_vtabstruct_7brainpy_2_c_21isotopic_distribution_TheoreticalPeak *__pyx_vtabptr_7brainpy_2_c_21isotopic_distribution_TheoreticalPeak;


/* "ms_peak_picker/_c/peak_set.pxd":2
 * 
 * cdef class PeakBase(object):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public double mz
 */

struct __pyx_vtabstruct_14ms_peak_picker_2_c_8peak_set_PeakBase {
  struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakBase *(*clone)(struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakBase *, int __pyx_skip_dispatch);
  struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakBase *(*copy)(struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakBase *, int __pyx_skip_dispatch);
};
static struct __pyx_vtabstruct_14ms_peak_picker_2_c_8peak_set_PeakBase *__pyx_vtabptr_14ms_peak_picker_2_c_8peak_set_PeakBase;


/* "ms_peak_picker/_c/peak_set.pxd":12
 * 
 * 
 * cdef class FittedPeak(PeakBase):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public double signal_to_noise
 */

struct __pyx_vtabstruct_14ms_peak_picker_2_c_8peak_set_FittedPeak {
  struct __pyx_vtabstruct_14ms_peak_picker_2_c_8peak_set_PeakBase __pyx_base;
  int (*_eq)(struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_FittedPeak *, struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_FittedPeak *, int __pyx_skip_dispatch);
  struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_FittedPeak *(*_create)(double, double, double, double, double, double, long, long, double);
};
static struct __pyx_vtabstruct_14ms_peak_picker_2_c_8peak_set_FittedPeak *__pyx_vtabptr_14ms_peak_picker_2_c_8peak_set_FittedPeak;


/* "ms_peak_picker/_c/peak_set.pxd":29
 *                             double area)
 * 
 * cdef class PeakSet(object):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public tuple peaks
 */

struct __pyx_vtabstruct_14ms_peak_picker_2_c_8peak_set_PeakSet {
  struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSet *(*_create)(PyObject *);
  PyObject *(*reindex)(struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSet *, int __pyx_skip_dispatch);
  size_t (*_index)(struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSet *, int __pyx_skip_dispatch);
  struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_FittedPeak *(*_get_nearest_peak)(struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSet *, double, double *);
  struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_FittedPeak *(*_has_peak)(struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSet *, double, struct __pyx_opt_args_14ms_peak_picker_2_c_8peak_set_7PeakSet__has_peak *__pyx_optional_args);
  struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSet *(*clone)(struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSet *, int __pyx_skip_dispatch);
  struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSet *(*copy)(struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSet *, int __pyx_skip_dispatch);
  struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSet *(*_between)(struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSet *, double, double);
  int (*_between_bounds)(struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSet *, double, double, size_t *, size_t *);
  PyObject *(*all_peaks_for)(struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSet *, double, int __pyx_skip_dispatch, struct __pyx_opt_args_14ms_peak_picker_2_c_8peak_set_7PeakSet_all_peaks_for *__pyx_optional_args);
  struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_FittedPeak *(*getitem)(struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSet *, size_t);
  size_t (*get_size)(struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSet *);
  int (*_eq)(struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSet *, struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSet *, int __pyx_skip_dispatch);
};
static struct __pyx_vtabstruct_14ms_peak_picker_2_c_8peak_set_PeakSet *__pyx_vtabptr_14ms_peak_picker_2_c_8peak_set_PeakSet;


/* "ms_peak_picker/_c/peak_set.pxd":83
 * 
 * 
 * cdef class PeakSetIndexed(PeakSet):             # <<<<<<<<<<<<<<
 *     cdef:
 *         double* mz_index
 */

struct __pyx_vtabstruct_14ms_peak_picker_2_c_8peak_set_PeakSetIndexed {
  struct __pyx_vtabstruct_14ms_peak_picker_2_c_8peak_set_PeakSet __pyx_base;
  PyObject *(*_allocate_index)(struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSetIndexed *, size_t, int __pyx_skip_dispatch);
  struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_FittedPeak *(*has_peak_hinted)(struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSetIndexed *, double, int __pyx_skip_dispatch, struct __pyx_opt_args_14ms_peak_picker_2_c_8peak_set_14PeakSetIndexed_has_peak_hinted *__pyx_optional_args);
};
static struct __pyx_vtabstruct_14ms_peak_picker_2_c_8peak_set_PeakSetIndexed *__pyx_vtabptr_14ms_peak_picker_2_c_8peak_set_PeakSetIndexed;


/* "ms_peak_picker/_c/peak_index.pxd":5
 * 
 * 
 * cdef class PeakIndex(object):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public np.ndarray mz_array
 */

struct __pyx_vtabstruct_14ms_peak_picker_2_c_10peak_index_PeakIndex {
  struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_FittedPeak *(*_has_peak)(struct __pyx_obj_14ms_peak_picker_2_c_10peak_index_PeakIndex *, double, struct __pyx_opt_args_14ms_peak_picker_2_c_10peak_index_9PeakIndex__has_peak *__pyx_optional_args);
  struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSet *(*_between)(struct __pyx_obj_14ms_peak_picker_2_c_10peak_index_PeakIndex *, double, double);
  PyObject *(*all_peaks_for)(struct __pyx_obj_14ms_peak_picker_2_c_10peak_index_PeakIndex *, double, int __pyx_skip_dispatch, struct __pyx_opt_args_14ms_peak_picker_2_c_10peak_index_9PeakIndex_all_peaks_for *__pyx_optional_args);
  size_t (*get_size)(struct __pyx_obj_14ms_peak_picker_2_c_10peak_index_PeakIndex *);
  struct __pyx_obj_14ms_peak_picker_2_c_10peak_index_PeakIndex *(*clone)(struct __pyx_obj_14ms_peak_picker_2_c_10peak_index_PeakIndex *, int __pyx_skip_dispatch);
  struct __pyx_obj_14ms_peak_picker_2_c_10peak_index_PeakIndex *(*copy)(struct __pyx_obj_14ms_peak_picker_2_c_10peak_index_PeakIndex *, int __pyx_skip_dispatch);
};
static struct __pyx_vtabstruct_14ms_peak_picker_2_c_10peak_index_PeakIndex *__pyx_vtabptr_14ms_peak_picker_2_c_10peak_index_PeakIndex;


/* "ms_deisotope/_c/averagine.pxd":12
 * cdef dict scale_dict(dict data, double factor)
 * 
 * cdef class Averagine(object):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public double base_mass
 */

struct __pyx_vtabstruct_12ms_deisotope_2_c_9averagine_Averagine {
  PyObject *(*scale)(struct __pyx_obj_12ms_deisotope_2_c_9averagine_Averagine *, double, int __pyx_skip_dispatch, struct __pyx_opt_args_12ms_deisotope_2_c_9averagine_9Averagine_scale *__pyx_optional_args);
  struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *(*isotopic_cluster)(struct __pyx_obj_12ms_deisotope_2_c_9averagine_Averagine *, double, int __pyx_skip_dispatch, struct __pyx_opt_args_12ms_deisotope_2_c_9averagine_9Averagine_isotopic_cluster *__pyx_optional_args);
  struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *(*_isotopic_cluster)(struct __pyx_obj_12ms_deisotope_2_c_9averagine_Averagine *, double, struct __pyx_opt_args_12ms_deisotope_2_c_9averagine_9Averagine__isotopic_cluster *__pyx_optional_args);
};
static struct __pyx_vtabstruct_12ms_deisotope_2_c_9averagine_Averagine *__pyx_vtabptr_12ms_deisotope_2_c_9averagine_Averagine;


/* "ms_deisotope/_c/averagine.pxd":23
 * 
 * @cython.final
 * cdef class TheoreticalIsotopicPattern(object):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public list peaklist
 */

struct __pyx_vtabstruct_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern {
  struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *(*_create)(PyObject *, double, double);
  struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *(*clone)(struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *, int __pyx_skip_dispatch);
  int (*_eq)(struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *, PyObject *, int __pyx_skip_dispatch);
  int (*_eq_inst)(struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *, struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *);
  struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *(*ignore_below)(struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *, int __pyx_skip_dispatch, struct __pyx_opt_args_12ms_deisotope_2_c_9averagine_26TheoreticalIsotopicPattern_ignore_below *__pyx_optional_args);
  struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *(*truncate_after)(struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *, int __pyx_skip_dispatch, struct __pyx_opt_args_12ms_deisotope_2_c_9averagine_26TheoreticalIsotopicPattern_truncate_after *__pyx_optional_args);
  struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *(*shift)(struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *, double, int __pyx_skip_dispatch);
  struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *(*scale)(struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *, PyObject *, int __pyx_skip_dispatch, struct __pyx_opt_args_12ms_deisotope_2_c_9averagine_26TheoreticalIsotopicPattern_scale *__pyx_optional_args);
  struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *(*scale_raw)(struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *, double, int __pyx_skip_dispatch);
  double (*drop_last_peak)(struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *, int __pyx_skip_dispatch);
  double (*total)(struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *, int __pyx_skip_dispatch);
  struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *(*normalize)(struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *, int __pyx_skip_dispatch);
  struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *(*_scale)(struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *, PyObject *, struct __pyx_opt_args_12ms_deisotope_2_c_9averagine_26TheoreticalIsotopicPattern__scale *__pyx_optional_args);
  struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *(*clone_shift)(struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *, double);
  struct __pyx_obj_7brainpy_2_c_21isotopic_distribution_TheoreticalPeak *(*get)(struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *, Py_ssize_t);
  size_t (*get_size)(struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *);
  double (*get_monoisotopic_mz)(struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *);
  PyObject *(*get_processed_peaks)(struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *);
  size_t (*basepeak_index)(struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *, int __pyx_skip_dispatch);
  PyObject *(*incremental_truncation)(struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *, double, int __pyx_skip_dispatch);
  struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *(*clone_drop_last)(struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *);
};
static struct __pyx_vtabstruct_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *__pyx_vtabptr_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern;


/* "ms_deisotope/_c/averagine.pxd":79
 * 
 * @cython.final
 * cdef class AveragineCache(object):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public dict backend
 */

struct __pyx_vtabstruct_12ms_deisotope_2_c_9averagine_AveragineCache {
  double (*_make_cache_key)(struct __pyx_obj_12ms_deisotope_2_c_9averagine_AveragineCache *, double);
  struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *(*has_mz_charge_pair)(struct __pyx_obj_12ms_deisotope_2_c_9averagine_AveragineCache *, double, struct __pyx_opt_args_12ms_deisotope_2_c_9averagine_14AveragineCache_has_mz_charge_pair *__pyx_optional_args);
  struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *(*isotopic_cluster)(struct __pyx_obj_12ms_deisotope_2_c_9averagine_AveragineCache *, double, int __pyx_skip_dispatch, struct __pyx_opt_args_12ms_deisotope_2_c_9averagine_14AveragineCache_isotopic_cluster *__pyx_optional_args);
};
static struct __pyx_vtabstruct_12ms_deisotope_2_c_9averagine_AveragineCache *__pyx_vtabptr_12ms_deisotope_2_c_9averagine_AveragineCache;


/* "ms_deisotope/_c/deconvoluter_base.pxd":25
 * 
 * 
 * cdef class DeconvoluterBase(object):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public bint use_subtraction
 */

struct __pyx_vtabstruct_12ms_deisotope_2_c_17deconvoluter_base_DeconvoluterBase {
  struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSet *(*between)(struct __pyx_obj_12ms_deisotope_2_c_17deconvoluter_base_DeconvoluterBase *, double, double, int __pyx_skip_dispatch);
  struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_FittedPeak *(*has_peak)(struct __pyx_obj_12ms_deisotope_2_c_17deconvoluter_base_DeconvoluterBase *, double, double, int __pyx_skip_dispatch);
  struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_FittedPeak *(*_has_peak)(struct __pyx_obj_12ms_deisotope_2_c_17deconvoluter_base_DeconvoluterBase *, double, double);
  PyObject *(*match_theoretical_isotopic_distribution)(struct __pyx_obj_12ms_deisotope_2_c_17deconvoluter_base_DeconvoluterBase *, PyObject *, int __pyx_skip_dispatch, struct __pyx_opt_args_12ms_deisotope_2_c_17deconvoluter_base_16DeconvoluterBase_match_theoretical_isotopic_distribution *__pyx_optional_args);
  PyObject *(*scale_theoretical_distribution)(struct __pyx_obj_12ms_deisotope_2_c_17deconvoluter_base_DeconvoluterBase *, struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *, PyObject *, int __pyx_skip_dispatch);
  struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitRecord *(*_evaluate_theoretical_distribution)(struct __pyx_obj_12ms_deisotope_2_c_17deconvoluter_base_DeconvoluterBase *, PyObject *, struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *, struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_FittedPeak *, int, int __pyx_skip_dispatch);
  PyObject *(*subtraction)(struct __pyx_obj_12ms_deisotope_2_c_17deconvoluter_base_DeconvoluterBase *, struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *, int __pyx_skip_dispatch, struct __pyx_opt_args_12ms_deisotope_2_c_17deconvoluter_base_16DeconvoluterBase_subtraction *__pyx_optional_args);
  PyObject *(*fit_incremental_truncation)(struct __pyx_obj_12ms_deisotope_2_c_17deconvoluter_base_DeconvoluterBase *, struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitRecord *, double, int __pyx_skip_dispatch);
  int (*_check_fit)(struct __pyx_obj_12ms_deisotope_2_c_17deconvoluter_base_DeconvoluterBase *, struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitRecord *, int __pyx_skip_dispatch);
  PyObject *(*_find_next_putative_peak)(struct __pyx_obj_12ms_deisotope_2_c_17deconvoluter_base_DeconvoluterBase *, double, int, int __pyx_skip_dispatch, struct __pyx_opt_args_12ms_deisotope_2_c_17deconvoluter_base_16DeconvoluterBase__find_next_putative_peak *__pyx_optional_args);
  PyObject *(*_find_previous_putative_peak)(struct __pyx_obj_12ms_deisotope_2_c_17deconvoluter_base_DeconvoluterBase *, double, int, int __pyx_skip_dispatch, struct __pyx_opt_args_12ms_deisotope_2_c_17deconvoluter_base_16DeconvoluterBase__find_previous_putative_peak *__pyx_optional_args);
  int (*_find_next_putative_peak_inplace)(struct __pyx_obj_12ms_deisotope_2_c_17deconvoluter_base_DeconvoluterBase *, double, int, PyObject *, struct __pyx_opt_args_12ms_deisotope_2_c_17deconvoluter_base_16DeconvoluterBase__find_next_putative_peak_inplace *__pyx_optional_args);
  int (*_find_previous_putative_peak_inplace)(struct __pyx_obj_12ms_deisotope_2_c_17deconvoluter_base_DeconvoluterBase *, double, int, PyObject *, struct __pyx_opt_args_12ms_deisotope_2_c_17deconvoluter_base_16DeconvoluterBase__find_previous_putative_peak_inplace *__pyx_optional_args);
};
static struct __pyx_vtabstruct_12ms_deisotope_2_c_17deconvoluter_base_DeconvoluterBase *__pyx_vtabptr_12ms_deisotope_2_c_17deconvoluter_base_DeconvoluterBase;


/* "ms_deisotope/_c/deconvoluter_base.pxd":57
 * 
 * 
 * cdef class AveragineDeconvoluterBase(DeconvoluterBase):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public AveragineCache averagine
 */

struct __pyx_vtabstruct_12ms_deisotope_2_c_17deconvoluter_base_AveragineDeconvoluterBase {
  struct __pyx_vtabstruct_12ms_deisotope_2_c_17deconvoluter_base_DeconvoluterBase __pyx_base;
  struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitRecord *(*fit_theoretical_distribution)(struct __pyx_obj_12ms_deisotope_2_c_17deconvoluter_base_AveragineDeconvoluterBase *, struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_FittedPeak *, double, int, int __pyx_skip_dispatch, struct __pyx_opt_args_12ms_deisotope_2_c_17deconvoluter_base_25AveragineDeconvoluterBase_fit_theoretical_distribution *__pyx_optional_args);
  PyObject *(*_fit_peaks_at_charges)(struct __pyx_obj_12ms_deisotope_2_c_17deconvoluter_base_AveragineDeconvoluterBase *, PyObject *, double, int __pyx_skip_dispatch, struct __pyx_opt_args_12ms_deisotope_2_c_17deconvoluter_base_25AveragineDeconvoluterBase__fit_peaks_at_charges *__pyx_optional_args);
};
static struct __pyx_vtabstruct_12ms_deisotope_2_c_17deconvoluter_base_AveragineDeconvoluterBase *__pyx_vtabptr_12ms_deisotope_2_c_17deconvoluter_base_AveragineDeconvoluterBase;


/* "ms_deisotope/_c/deconvoluter_base.pxd":69
 * 
 * 
 * cdef class MultiAveragineDeconvoluterBase(DeconvoluterBase):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public list averagines
 */

struct __pyx_vtabstruct_12ms_deisotope_2_c_17deconvoluter_base_MultiAveragineDeconvoluterBase {
  struct __pyx_vtabstruct_12ms_deisotope_2_c_17deconvoluter_base_DeconvoluterBase __pyx_base;
  struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitRecord *(*fit_theoretical_distribution)(struct __pyx_obj_12ms_deisotope_2_c_17deconvoluter_base_MultiAveragineDeconvoluterBase *, struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_FittedPeak *, double, int, struct __pyx_obj_12ms_deisotope_2_c_9averagine_AveragineCache *, int __pyx_skip_dispatch, struct __pyx_opt_args_12ms_deisotope_2_c_17deconvoluter_base_30MultiAveragineDeconvoluterBase_fit_theoretical_distribution *__pyx_optional_args);
  PyObject *(*_fit_peaks_at_charges)(struct __pyx_obj_12ms_deisotope_2_c_17deconvoluter_base_MultiAveragineDeconvoluterBase *, PyObject *, double, int __pyx_skip_dispatch, struct __pyx_opt_args_12ms_deisotope_2_c_17deconvoluter_base_30MultiAveragineDeconvoluterBase__fit_peaks_at_charges *__pyx_optional_args);
};
static struct __pyx_vtabstruct_12ms_deisotope_2_c_17deconvoluter_base_MultiAveragineDeconvoluterBase *__pyx_vtabptr_12ms_deisotope_2_c_17deconvoluter_base_MultiAveragineDeconvoluterBase;


/* "ms_deisotope/_c/deconvoluter_base.pxd":91
 * 
 * 
 * cdef class ChargeIterator(object):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public int lower
 */

struct __pyx_vtabstruct_12ms_deisotope_2_c_17deconvoluter_base_ChargeIterator {
  struct __pyx_obj_12ms_deisotope_2_c_17deconvoluter_base_ChargeIterator *(*_create)(int, int);
  struct __pyx_obj_12ms_deisotope_2_c_17deconvoluter_base_ChargeIterator *(*from_tuple)(PyObject *);
  struct __pyx_obj_12ms_deisotope_2_c_17deconvoluter_base_ChargeIterator *(*from_quickcharge)(PyObject *, struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSet *, struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_FittedPeak *);
  PyObject *(*sequence_from_quickcharge)(struct __pyx_obj_12ms_deisotope_2_c_17deconvoluter_base_ChargeIterator *, struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSet *, struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_FittedPeak *, int __pyx_skip_dispatch);
  PyObject *(*make_sequence)(struct __pyx_obj_12ms_deisotope_2_c_17deconvoluter_base_ChargeIterator *, int __pyx_skip_dispatch);
  void (*release_sequence)(struct __pyx_obj_12ms_deisotope_2_c_17deconvoluter_base_ChargeIterator *);
  void (*set_bounds)(struct __pyx_obj_12ms_deisotope_2_c_17deconvoluter_base_ChargeIterator *, int, int);
  int (*has_more)(struct __pyx_obj_12ms_deisotope_2_c_17deconvoluter_base_ChargeIterator *, int __pyx_skip_dispatch);
  PyObject *(*reset)(struct __pyx_obj_12ms_deisotope_2_c_17deconvoluter_base_ChargeIterator *, int __pyx_skip_dispatch);
  int (*get_next_value)(struct __pyx_obj_12ms_deisotope_2_c_17deconvoluter_base_ChargeIterator *, int __pyx_skip_dispatch);
  size_t (*get_size)(struct __pyx_obj_12ms_deisotope_2_c_17deconvoluter_base_ChargeIterator *);
};
static struct __pyx_vtabstruct_12ms_deisotope_2_c_17deconvoluter_base_ChargeIterator *__pyx_vtabptr_12ms_deisotope_2_c_17deconvoluter_base_ChargeIterator;


/* "ms_deisotope/_c/scoring.pxd":16
 * 
 * 
 * cdef class IsotopicFitRecord(object):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public FittedPeak seed_peak
 */

struct __pyx_vtabstruct_12ms_deisotope_2_c_7scoring_IsotopicFitRecord {
  struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitRecord *(*_create)(struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_FittedPeak *, double, int, struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *, PyObject *, struct __pyx_opt_args_12ms_deisotope_2_c_7scoring_17IsotopicFitRecord__create *__pyx_optional_args);
  int (*_eq)(struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitRecord *, struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitRecord *, int __pyx_skip_dispatch);
  int (*_ne)(struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitRecord *, struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitRecord *, int __pyx_skip_dispatch);
  int (*_lt)(struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitRecord *, struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitRecord *, int __pyx_skip_dispatch);
  int (*_gt)(struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitRecord *, struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitRecord *, int __pyx_skip_dispatch);
};
static struct __pyx_vtabstruct_12ms_deisotope_2_c_7scoring_IsotopicFitRecord *__pyx_vtabptr_12ms_deisotope_2_c_7scoring_IsotopicFitRecord;


/* "ms_deisotope/_c/scoring.pxd":38
 * 
 * 
 * cdef class FitSelectorBase(object):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public double minimum_score
 */

struct __pyx_vtabstruct_12ms_deisotope_2_c_7scoring_FitSelectorBase {
  struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitRecord *(*best)(struct __pyx_obj_12ms_deisotope_2_c_7scoring_FitSelectorBase *, PyObject *, int __pyx_skip_dispatch);
  struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitRecord *(*_best_from_set)(struct __pyx_obj_12ms_deisotope_2_c_7scoring_FitSelectorBase *, PyObject *);
  int (*reject)(struct __pyx_obj_12ms_deisotope_2_c_7scoring_FitSelectorBase *, struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitRecord *, int __pyx_skip_dispatch);
  int (*reject_score)(struct __pyx_obj_12ms_deisotope_2_c_7scoring_FitSelectorBase *, double, int __pyx_skip_dispatch);
  int (*is_maximizing)(struct __pyx_obj_12ms_deisotope_2_c_7scoring_FitSelectorBase *, int __pyx_skip_dispatch);
};
static struct __pyx_vtabstruct_12ms_deisotope_2_c_7scoring_FitSelectorBase *__pyx_vtabptr_12ms_deisotope_2_c_7scoring_FitSelectorBase;


/* "ms_deisotope/_c/scoring.pxd":50
 * 
 * 
 * cdef class IsotopicFitterBase(object):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public FitSelectorBase select
 */

struct __pyx_vtabstruct_12ms_deisotope_2_c_7scoring_IsotopicFitterBase {
  double (*_evaluate)(struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitterBase *, struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSet *, PyObject *, PyObject *, int __pyx_skip_dispatch);
  int (*reject)(struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitterBase *, struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitRecord *, int __pyx_skip_dispatch);
  int (*reject_score)(struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitterBase *, double, int __pyx_skip_dispatch);
  int (*is_maximizing)(struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitterBase *, int __pyx_skip_dispatch);
  struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitterBase *(*_configure)(struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitterBase *, struct __pyx_obj_12ms_deisotope_2_c_17deconvoluter_base_DeconvoluterBase *, PyObject *, int __pyx_skip_dispatch);
};
static struct __pyx_vtabstruct_12ms_deisotope_2_c_7scoring_IsotopicFitterBase *__pyx_vtabptr_12ms_deisotope_2_c_7scoring_IsotopicFitterBase;


/* "ms_deisotope/_c/scoring.pxd":62
 * 
 * 
 * cdef class LeastSquaresFitter(IsotopicFitterBase):             # <<<<<<<<<<<<<<
 *     pass
 * 
 */

struct __pyx_vtabstruct_12ms_deisotope_2_c_7scoring_LeastSquaresFitter {
  struct __pyx_vtabstruct_12ms_deisotope_2_c_7scoring_IsotopicFitterBase __pyx_base;
};
static struct __pyx_vtabstruct_12ms_deisotope_2_c_7scoring_LeastSquaresFitter *__pyx_vtabptr_12ms_deisotope_2_c_7scoring_LeastSquaresFitter;


/* "ms_deisotope/_c/scoring.pxd":66
 * 
 * 
 * cdef class GTestFitter(IsotopicFitterBase):             # <<<<<<<<<<<<<<
 *     pass
 * 
 */

struct __pyx_vtabstruct_12ms_deisotope_2_c_7scoring_GTestFitter {
  struct __pyx_vtabstruct_12ms_deisotope_2_c_7scoring_IsotopicFitterBase __pyx_base;
};
static struct __pyx_vtabstruct_12ms_deisotope_2_c_7scoring_GTestFitter *__pyx_vtabptr_12ms_deisotope_2_c_7scoring_GTestFitter;


/* "ms_deisotope/_c/scoring.pxd":69
 *     pass
 * 
 * cdef class ScaledGTestFitter(IsotopicFitterBase):             # <<<<<<<<<<<<<<
 *     pass
 * 
 */

struct __pyx_vtabstruct_12ms_deisotope_2_c_7scoring_ScaledGTestFitter {
  struct __pyx_vtabstruct_12ms_deisotope_2_c_7scoring_IsotopicFitterBase __pyx_base;
};
static struct __pyx_vtabstruct_12ms_deisotope_2_c_7scoring_ScaledGTestFitter *__pyx_vtabptr_12ms_deisotope_2_c_7scoring_ScaledGTestFitter;


/* "ms_deisotope/_c/scoring.pxd":72
 *     pass
 * 
 * cdef class MSDeconVFitter(IsotopicFitterBase):             # <<<<<<<<<<<<<<
 *     cdef public double mass_error_tolerance
 * 
 */

struct __pyx_vtabstruct_12ms_deisotope_2_c_7scoring_MSDeconVFitter {
  struct __pyx_vtabstruct_12ms_deisotope_2_c_7scoring_IsotopicFitterBase __pyx_base;
  double (*score_peak)(struct __pyx_obj_12ms_deisotope_2_c_7scoring_MSDeconVFitter *, struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_FittedPeak *, struct __pyx_obj_7brainpy_2_c_21isotopic_distribution_TheoreticalPeak *, struct __pyx_opt_args_12ms_deisotope_2_c_7scoring_14MSDeconVFitter_score_peak *__pyx_optional_args);
};
static struct __pyx_vtabstruct_12ms_deisotope_2_c_7scoring_MSDeconVFitter *__pyx_vtabptr_12ms_deisotope_2_c_7scoring_MSDeconVFitter;


/* "ms_deisotope/_c/scoring.pxd":78
 * 
 * 
 * cdef class PenalizedMSDeconVFitter(IsotopicFitterBase):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public double mass_error_tolerance
 */

struct __pyx_vtabstruct_12ms_deisotope_2_c_7scoring_PenalizedMSDeconVFitter {
  struct __pyx_vtabstruct_12ms_deisotope_2_c_7scoring_IsotopicFitterBase __pyx_base;
};
static struct __pyx_vtabstruct_12ms_deisotope_2_c_7scoring_PenalizedMSDeconVFitter *__pyx_vtabptr_12ms_deisotope_2_c_7scoring_PenalizedMSDeconVFitter;


/* "ms_deisotope/_c/scoring.pxd":84
 * 
 * 
 * cdef class FunctionScorer(IsotopicFitterBase):             # <<<<<<<<<<<<<<
 *     cdef:
 *         object function
 */

struct __pyx_vtabstruct_12ms_deisotope_2_c_7scoring_FunctionScorer {
  struct __pyx_vtabstruct_12ms_deisotope_2_c_7scoring_IsotopicFitterBase __pyx_base;
};
static struct __pyx_vtabstruct_12ms_deisotope_2_c_7scoring_FunctionScorer *__pyx_vtabptr_12ms_deisotope_2_c_7scoring_FunctionScorer;


/* "ms_deisotope/_c/scoring.pxd":89
 * 
 * 
 * cdef class InterferenceDetection(object):             # <<<<<<<<<<<<<<
 *     cdef public PeakSet peaklist
 * 
 */

struct __pyx_vtabstruct_12ms_deisotope_2_c_7scoring_InterferenceDetection {
  double (*detect_interference)(struct __pyx_obj_12ms_deisotope_2_c_7scoring_InterferenceDetection *, PyObject *, struct __pyx_opt_args_12ms_deisotope_2_c_7scoring_21InterferenceDetection_detect_interference *__pyx_optional_args);
};
static struct __pyx_vtabstruct_12ms_deisotope_2_c_7scoring_InterferenceDetection *__pyx_vtabptr_12ms_deisotope_2_c_7scoring_InterferenceDetection;


/* "ms_deisotope/_c/scoring.pxd":95
 * 
 * 
 * cdef class DistinctPatternFitter(IsotopicFitterBase):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public InterferenceDetection interference_detector
 */

struct __pyx_vtabstruct_12ms_deisotope_2_c_7scoring_DistinctPatternFitter {
  struct __pyx_vtabstruct_12ms_deisotope_2_c_7scoring_IsotopicFitterBase __pyx_base;
};
static struct __pyx_vtabstruct_12ms_deisotope_2_c_7scoring_DistinctPatternFitter *__pyx_vtabptr_12ms_deisotope_2_c_7scoring_DistinctPatternFitter;


/* "ms_deisotope/_c/scoring.pxd":102
 *         public double domain_scale
 * 
 * cdef class ScaledPenalizedMSDeconvFitter(IsotopicFitterBase):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public double scale_factor
 */

struct __pyx_vtabstruct_12ms_deisotope_2_c_7scoring_ScaledPenalizedMSDeconvFitter {
  struct __pyx_vtabstruct_12ms_deisotope_2_c_7scoring_IsotopicFitterBase __pyx_base;
  double (*_calculate_scale_factor)(struct __pyx_obj_12ms_deisotope_2_c_7scoring_ScaledPenalizedMSDeconvFitter *, struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSet *, int __pyx_skip_dispatch);
  void (*scale_fitted_peaks)(struct __pyx_obj_12ms_deisotope_2_c_7scoring_ScaledPenalizedMSDeconvFitter *, PyObject *, double);
  void (*scale_theoretical_peaks)(struct __pyx_obj_12ms_deisotope_2_c_7scoring_ScaledPenalizedMSDeconvFitter *, PyObject *, double);
};
static struct __pyx_vtabstruct_12ms_deisotope_2_c_7scoring_ScaledPenalizedMSDeconvFitter *__pyx_vtabptr_12ms_deisotope_2_c_7scoring_ScaledPenalizedMSDeconvFitter;


/* "ms_deisotope/_c/scoring.pxd":112
 * 
 * 
 * cdef class DotProductFitter(IsotopicFitterBase):             # <<<<<<<<<<<<<<
 *     pass
 */

struct __pyx_vtabstruct_12ms_deisotope_2_c_7scoring_DotProductFitter {
  struct __pyx_vtabstruct_12ms_deisotope_2_c_7scoring_IsotopicFitterBase __pyx_base;
};
static struct __pyx_vtabstruct_12ms_deisotope_2_c_7scoring_DotProductFitter *__pyx_vtabptr_12ms_deisotope_2_c_7scoring_DotProductFitter;


/* "ms_deisotope/_c/peak_dependency_network/subgraph.pyx":13
 * 
 * @cython.final
 * cdef class FitNode(SpanningMixin):             # <<<<<<<<<<<<<<
 *     def __init__(self, IsotopicFitRecord fit, size_t index=-1):
 *         self.index = index
 */

struct __pyx_vtabstruct_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_FitNode {
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  void (*_init_fields)(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_FitNode *, PyObject *);
  struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_FitNode *(*_create)(struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitRecord *, size_t);
};
static struct __pyx_vtabstruct_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_FitNode *__pyx_vtabptr_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_FitNode;
static int __pyx_f_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_7FitNode_isdisjoint(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_FitNode *, struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_FitNode *, int __pyx_skip_dispatch);
static PyObject *__pyx_f_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_7FitNode_visit(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_FitNode *, struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_FitNode *, int __pyx_skip_dispatch);
static void __pyx_f_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_7FitNode__init_fields(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_FitNode *, PyObject *);
static struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_FitNode *__pyx_f_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_7FitNode__create(struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitRecord *, size_t);


/* "ms_deisotope/_c/peak_dependency_network/subgraph.pyx":156
 * 
 * @cython.freelist(5)
 * cdef class ConnectedSubgraph(object):             # <<<<<<<<<<<<<<
 *     def __init__(self, object fits, bint maximize=True):
 *         self.maximize = maximize
 */

struct __pyx_vtabstruct_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_ConnectedSubgraph {
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  void (*populate_edges)(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_ConnectedSubgraph *);
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};
static struct __pyx_vtabstruct_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_ConnectedSubgraph *__pyx_vtabptr_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_ConnectedSubgraph;


/* "ms_deisotope/_c/peak_dependency_network/subgraph.pyx":133
 * @cython.final
 * @cython.freelist(5)
 * cdef class GreedySubgraphSelection(object):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public list intervals
 */

struct __pyx_vtabstruct_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_GreedySubgraphSelection {
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};
static struct __pyx_vtabstruct_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_GreedySubgraphSelection *__pyx_vtabptr_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_GreedySubgraphSelection;
static void __pyx_f_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_23GreedySubgraphSelection__build_layers(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_GreedySubgraphSelection *);
static PyObject *__pyx_f_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_23GreedySubgraphSelection__select_best_subset(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_GreedySubgraphSelection *);
static PyObject *__pyx_f_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_23GreedySubgraphSelection_select(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_GreedySubgraphSelection *, int __pyx_skip_dispatch);

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#define __Pyx_PyErr_SetNone(exc) PyErr_SetNone(exc)
#endif
#else
#define __Pyx_PyErr_Clear() PyErr_Clear()
#define __Pyx_PyErr_SetNone(exc) PyErr_SetNone(exc)
#define __Pyx_ErrRestoreWithState(type, value, tb)  PyErr_Restore(type, value, tb)
#define __Pyx_ErrFetchWithState(type, value, tb)  PyErr_Fetch(type, value, tb)
#define __Pyx_ErrRestoreInState(tstate, type, value, tb)  PyErr_Restore(type, value, tb)
#define __Pyx_ErrFetchInState(tstate, type, value, tb)  PyErr_Fetch(type, value, tb)
#define __Pyx_ErrRestore(type, value, tb)  PyErr_Restore(type, value, tb)
#define __Pyx_ErrFetch(type, value, tb)  PyErr_Fetch(type, value, tb)
#endif

/* WriteUnraisableException.proto */
static void __Pyx_WriteUnraisable(const char *name, int clineno,
                                  int lineno, const char *filename,
                                  int full_traceback, int nogil);

/* PyCFunctionFastCall.proto */
#if CYTHON_FAST_PYCCALL
static CYTHON_INLINE PyObject *__Pyx_PyCFunction_FastCall(PyObject *func, PyObject **args, Py_ssize_t nargs);
#else
#define __Pyx_PyCFunction_FastCall(func, args, nargs)  (assert(0), NULL)
#endif

/* PyFunctionFastCall.proto */
#if CYTHON_FAST_PYCALL
#define __Pyx_PyFunction_FastCall(func, args, nargs)\
    __Pyx_PyFunction_FastCallDict((func), (args), (nargs), NULL)
#if 1 || PY_VERSION_HEX < 0x030600B1
static PyObject *__Pyx_PyFunction_FastCallDict(PyObject *func, PyObject **args, Py_ssize_t nargs, PyObject *kwargs);
#else
#define __Pyx_PyFunction_FastCallDict(func, args, nargs, kwargs) _PyFunction_FastCallDict(func, args, nargs, kwargs)
#endif
#define __Pyx_BUILD_ASSERT_EXPR(cond)\
    (sizeof(char [1 - 2*!(cond)]) - 1)
#ifndef Py_MEMBER_SIZE
#define Py_MEMBER_SIZE(type, member) sizeof(((type *)0)->member)
#endif
  static size_t __pyx_pyframe_localsplus_offset = 0;
  #include "frameobject.h"
  #define __Pxy_PyFrame_Initialize_Offsets()\
    ((void)__Pyx_BUILD_ASSERT_EXPR(sizeof(PyFrameObject) == offsetof(PyFrameObject, f_localsplus) + Py_MEMBER_SIZE(PyFrameObject, f_localsplus)),\
     (void)(__pyx_pyframe_localsplus_offset = ((size_t)PyFrame_Type.tp_basicsize) - Py_MEMBER_SIZE(PyFrameObject, f_localsplus)))
  #define __Pyx_PyFrame_GetLocalsplus(frame)\
    (assert(__pyx_pyframe_localsplus_offset), (PyObject **)(((char *)(frame)) + __pyx_pyframe_localsplus_offset))
#endif

/* PyObjectCall.proto */
#if CYTHON_COMPILING_IN_CPYTHON
static CYTHON_INLINE PyObject* __Pyx_PyObject_Call(PyObject *func, PyObject *arg, PyObject *kw);
#else
#define __Pyx_PyObject_Call(func, arg, kw) PyObject_Call(func, arg, kw)
#endif

/* PyObjectCall2Args.proto */
static CYTHON_UNUSED PyObject* __Pyx_PyObject_Call2Args(PyObject* function, PyObject* arg1, PyObject* arg2);

/* PyObjectCallMethO.proto */
#if CYTHON_COMPILING_IN_CPYTHON
static CYTHON_INLINE PyObject* __Pyx_PyObject_CallMethO(PyObject *func, PyObject *arg);
#endif

/* PyObjectCallOneArg.proto */
static CYTHON_INLINE PyObject* __Pyx_PyObject_CallOneArg(PyObject *func, PyObject *arg);

/* ExtTypeTest.proto */
static CYTHON_INLINE int __Pyx_TypeTest(PyObject *obj, PyTypeObject *type);

/* PyErrExceptionMatches.proto */
#if CYTHON_FAST_THREAD_STATE
#define __Pyx_PyErr_ExceptionMatches(err) __Pyx_PyErr_ExceptionMatchesInState(__pyx_tstate, err)
static CYTHON_INLINE int __Pyx_PyErr_ExceptionMatchesInState(PyThreadState* tstate, PyObject* err);
#else
#define __Pyx_PyErr_ExceptionMatches(err)  PyErr_ExceptionMatches(err)
#endif

/* GetAttr.proto */
static CYTHON_INLINE PyObject *__Pyx_GetAttr(PyObject *, PyObject *);

/* GetAttr3.proto */
static CYTHON_INLINE PyObject *__Pyx_GetAttr3(PyObject *, PyObject *, PyObject *);

/* PyDictVersioning.proto */
#if CYTHON_USE_DICT_VERSIONS && CYTHON_USE_TYPE_SLOTS
#define __PYX_DICT_VERSION_INIT  ((PY_UINT64_T) -1)
#define __PYX_GET_DICT_VERSION(dict)  (((PyDictObject*)(dict))->ma_version_tag)
#define __PYX_UPDATE_DICT_CACHE(dict, value, cache_var, version_var)\
    (version_var) = __PYX_GET_DICT_VERSION(dict);\
    (cache_var) = (value);
#define __PYX_PY_DICT_LOOKUP_IF_MODIFIED(VAR, DICT, LOOKUP) {\
    static PY_UINT64_T __pyx_dict_version = 0;\
    static PyObject *__pyx_dict_cached_value = NULL;\
    if (likely(__PYX_GET_DICT_VERSION(DICT) == __pyx_dict_version)) {\
        (VAR) = __pyx_dict_cached_value;\
    } else {\
        (VAR) = __pyx_dict_cached_value = (LOOKUP);\
        __pyx_dict_version = __PYX_GET_DICT_VERSION(DICT);\
    }\
}
static CYTHON_INLINE PY_UINT64_T __Pyx_get_tp_dict_version(PyObject *obj);
static CYTHON_INLINE PY_UINT64_T __Pyx_get_object_dict_version(PyObject *obj);
static CYTHON_INLINE int __Pyx_object_dict_version_matches(PyObject* obj, PY_UINT64_T tp_dict_version, PY_UINT64_T obj_dict_version);
#else
#define __PYX_GET_DICT_VERSION(dict)  (0)
#define __PYX_UPDATE_DICT_CACHE(dict, value, cache_var, version_var)
#define __PYX_PY_DICT_LOOKUP_IF_MODIFIED(VAR, DICT, LOOKUP)  (VAR) = (LOOKUP);
#endif

/* GetModuleGlobalName.proto */
#if CYTHON_USE_DICT_VERSIONS
#define __Pyx_GetModuleGlobalName(var, name)  {\
    static PY_UINT64_T __pyx_dict_version = 0;\
    static PyObject *__pyx_dict_cached_value = NULL;\
    (var) = (likely(__pyx_dict_version == __PYX_GET_DICT_VERSION(__pyx_d))) ?\
        (likely(__pyx_dict_cached_value) ? __Pyx_NewRef(__pyx_dict_cached_value) : __Pyx_GetBuiltinName(name)) :\
        __Pyx__GetModuleGlobalName(name, &__pyx_dict_version, &__pyx_dict_cached_value);\
}
#define __Pyx_GetModuleGlobalNameUncached(var, name)  {\
    PY_UINT64_T __pyx_dict_version;\
    PyObject *__pyx_dict_cached_value;\
    (var) = __Pyx__GetModuleGlobalName(name, &__pyx_dict_version, &__pyx_dict_cached_value);\
}
static PyObject *__Pyx__GetModuleGlobalName(PyObject *name, PY_UINT64_T *dict_version, PyObject **dict_cached_value);
#else
#define __Pyx_GetModuleGlobalName(var, name)  (var) = __Pyx__GetModuleGlobalName(name)
#define __Pyx_GetModuleGlobalNameUncached(var, name)  (var) = __Pyx__GetModuleGlobalName(name)
static CYTHON_INLINE PyObject *__Pyx__GetModuleGlobalName(PyObject *name);
#endif

/* ListAppend.proto */
#if CYTHON_USE_PYLIST_INTERNALS && CYTHON_ASSUME_SAFE_MACROS
static CYTHON_INLINE int __Pyx_PyList_Append(PyObject* list, PyObject* x) {
    PyListObject* L = (PyListObject*) list;
    Py_ssize_t len = Py_SIZE(list);
    if (likely(L->allocated > len) & likely(len > (L->allocated >> 1))) {
        Py_INCREF(x);
        PyList_SET_ITEM(list, len, x);
        __Pyx_SET_SIZE(list, len + 1);
        return 0;
    }
    return PyList_Append(list, x);
}
#else
#define __Pyx_PyList_Append(L,x) PyList_Append(L,x)
#endif

/* GetItemInt.proto */
#define __Pyx_GetItemInt(o, i, type, is_signed, to_py_func, is_list, wraparound, boundscheck)\
    (__Pyx_fits_Py_ssize_t(i, type, is_signed) ?\
    __Pyx_GetItemInt_Fast(o, (Py_ssize_t)i, is_list, wraparound, boundscheck) :\
    (is_list ? (PyErr_SetString(PyExc_IndexError, "list index out of range"), (PyObject*)NULL) :\
               __Pyx_GetItemInt_Generic(o, to_py_func(i))))
#define __Pyx_GetItemInt_List(o, i, type, is_signed, to_py_func, is_list, wraparound, boundscheck)\
    (__Pyx_fits_Py_ssize_t(i, type, is_signed) ?\
    __Pyx_GetItemInt_List_Fast(o, (Py_ssize_t)i, wraparound, boundscheck) :\
    (PyErr_SetString(PyExc_IndexError, "list index out of range"), (PyObject*)NULL))
static CYTHON_INLINE PyObject *__Pyx_GetItemInt_List_Fast(PyObject *o, Py_ssize_t i,
                                                              int wraparound, int boundscheck);
#define __Pyx_GetItemInt_Tuple(o, i, type, is_signed, to_py_func, is_list, wraparound, boundscheck)\
    (__Pyx_fits_Py_ssize_t(i, type, is_signed) ?\
    __Pyx_GetItemInt_Tuple_Fast(o, (Py_ssize_t)i, wraparound, boundscheck) :\
    (PyErr_SetString(PyExc_IndexError, "tuple index out of range"), (PyObject*)NULL))
static CYTHON_INLINE PyObject *__Pyx_GetItemInt_Tuple_Fast(PyObject *o, Py_ssize_t i,
                                                              int wraparound, int boundscheck);
static PyObject *__Pyx_GetItemInt_Generic(PyObject *o, PyObject* j);
static CYTHON_INLINE PyObject *__Pyx_GetItemInt_Fast(PyObject *o, Py_ssize_t i,
                                                     int is_list, int wraparound, int boundscheck);

/* ObjectGetItem.proto */
#if CYTHON_USE_TYPE_SLOTS
static CYTHON_INLINE PyObject *__Pyx_PyObject_GetItem(PyObject *obj, PyObject* key);
#else
#define __Pyx_PyObject_GetItem(obj, key)  PyObject_GetItem(obj, key)
#endif

/* IncludeStringH.proto */
#include <string.h>

/* BytesEquals.proto */
static CYTHON_INLINE int __Pyx_PyBytes_Equals(PyObject* s1, PyObject* s2, int equals);

/* UnicodeEquals.proto */
static CYTHON_INLINE int __Pyx_PyUnicode_Equals(PyObject* s1, PyObject* s2, int equals);

/* StrEquals.proto */
#if PY_MAJOR_VERSION >= 3
#define __Pyx_PyString_Equals __Pyx_PyUnicode_Equals
#else
#define __Pyx_PyString_Equals __Pyx_PyBytes_Equals
#endif

/* RaiseException.proto */
static void __Pyx_Raise(PyObject *type, PyObject *value, PyObject *tb, PyObject *cause);

/* Import.proto */
static PyObject *__Pyx_Import(PyObject *name, PyObject *from_list, int level);

/* ImportFrom.proto */
static PyObject* __Pyx_ImportFrom(PyObject* module, PyObject* name);

/* HasAttr.proto */
static CYTHON_INLINE int __Pyx_HasAttr(PyObject *, PyObject *);

/* GetTopmostException.proto */
#if CYTHON_USE_EXC_INFO_STACK
static _PyErr_StackItem * __Pyx_PyErr_GetTopmostException(PyThreadState *tstate);
#endif

/* SaveResetException.proto */
#if CYTHON_FAST_THREAD_STATE
#define __Pyx_ExceptionSave(type, value, tb)  __Pyx__ExceptionSave(__pyx_tstate, type, value, tb)
static CYTHON_INLINE void __Pyx__ExceptionSave(PyThreadState *tstate, PyObject **type, PyObject **value, PyObject **tb);
#define __Pyx_ExceptionReset(type, value, tb)  __Pyx__ExceptionReset(__pyx_tstate, type, value, tb)
static CYTHON_INLINE void __Pyx__ExceptionReset(PyThreadState *tstate, PyObject *type, PyObject *value, PyObject *tb);
#else
#define __Pyx_ExceptionSave(type, value, tb)   PyErr_GetExcInfo(type, value, tb)
#define __Pyx_ExceptionReset(type, value, tb)  PyErr_SetExcInfo(type, value, tb)
#endif

/* GetException.proto */
#if CYTHON_FAST_THREAD_STATE
#define __Pyx_GetException(type, value, tb)  __Pyx__GetException(__pyx_tstate, type, value, tb)
static int __Pyx__GetException(PyThreadState *tstate, PyObject **type, PyObject **value, PyObject **tb);
#else
static int __Pyx_GetException(PyObject **type, PyObject **value, PyObject **tb);
#endif

/* CallNextTpDealloc.proto */
static void __Pyx_call_next_tp_dealloc(PyObject* obj, destructor current_tp_dealloc);

/* CallNextTpTraverse.proto */
static int __Pyx_call_next_tp_traverse(PyObject* obj, visitproc v, void *a, traverseproc current_tp_traverse);

/* CallNextTpClear.proto */
static void __Pyx_call_next_tp_clear(PyObject* obj, inquiry current_tp_dealloc);

/* TypeImport.proto */
#ifndef __PYX_HAVE_RT_ImportType_proto
#define __PYX_HAVE_RT_ImportType_proto
enum __Pyx_ImportType_CheckSize {
   __Pyx_ImportType_CheckSize_Error = 0,
   __Pyx_ImportType_CheckSize_Warn = 1,
   __Pyx_ImportType_CheckSize_Ignore = 2
};
static PyTypeObject *__Pyx_ImportType(PyObject* module, const char *module_name, const char *class_name, size_t size, enum __Pyx_ImportType_CheckSize check_size);
#endif

/* GetVTable.proto */
static void* __Pyx_GetVtable(PyObject *dict);

/* PyObject_GenericGetAttrNoDict.proto */
#if CYTHON_USE_TYPE_SLOTS && CYTHON_USE_PYTYPE_LOOKUP && PY_VERSION_HEX < 0x03070000
static CYTHON_INLINE PyObject* __Pyx_PyObject_GenericGetAttrNoDict(PyObject* obj, PyObject* attr_name);
#else
#define __Pyx_PyObject_GenericGetAttrNoDict PyObject_GenericGetAttr
#endif

/* SetVTable.proto */
static int __Pyx_SetVtable(PyObject *dict, void *vtable);

/* PyObjectGetAttrStrNoError.proto */
static CYTHON_INLINE PyObject* __Pyx_PyObject_GetAttrStrNoError(PyObject* obj, PyObject* attr_name);

/* SetupReduce.proto */
static int __Pyx_setup_reduce(PyObject* type_obj);

/* PyObject_GenericGetAttr.proto */
#if CYTHON_USE_TYPE_SLOTS && CYTHON_USE_PYTYPE_LOOKUP && PY_VERSION_HEX < 0x03070000
static PyObject* __Pyx_PyObject_GenericGetAttr(PyObject* obj, PyObject* attr_name);
#else
#define __Pyx_PyObject_GenericGetAttr PyObject_GenericGetAttr
#endif

/* CLineInTraceback.proto */
#ifdef CYTHON_CLINE_IN_TRACEBACK
#define __Pyx_CLineForTraceback(tstate, c_line)  (((CYTHON_CLINE_IN_TRACEBACK)) ? c_line : 0)
#else
static int __Pyx_CLineForTraceback(PyThreadState *tstate, int c_line);
#endif

/* CodeObjectCache.proto */
typedef struct {
    PyCodeObject* code_object;
    int code_line;
} __Pyx_CodeObjectCacheEntry;
struct __Pyx_CodeObjectCache {
    int count;
    int max_count;
    __Pyx_CodeObjectCacheEntry* entries;
};
static struct __Pyx_CodeObjectCache __pyx_code_cache = {0,0,NULL};
static int __pyx_bisect_code_objects(__Pyx_CodeObjectCacheEntry* entries, int count, int code_line);
static PyCodeObject *__pyx_find_code_object(int code_line);
static void __pyx_insert_code_object(int code_line, PyCodeObject* code_object);

/* AddTraceback.proto */
static void __Pyx_AddTraceback(const char *funcname, int c_line,
                               int py_line, const char *filename);

/* CIntToPy.proto */
static CYTHON_INLINE PyObject* __Pyx_PyInt_From_long(long value);

/* RealImag.proto */
#if CYTHON_CCOMPLEX
  #ifdef __cplusplus
    #define __Pyx_CREAL(z) ((z).real())
    #define __Pyx_CIMAG(z) ((z).imag())
  #else
    #define __Pyx_CREAL(z) (__real__(z))
    #define __Pyx_CIMAG(z) (__imag__(z))
  #endif
#else
    #define __Pyx_CREAL(z) ((z).real)
    #define __Pyx_CIMAG(z) ((z).imag)
#endif
#if defined(__cplusplus) && CYTHON_CCOMPLEX\
        && (defined(_WIN32) || defined(__clang__) || (defined(__GNUC__) && (__GNUC__ >= 5 || __GNUC__ == 4 && __GNUC_MINOR__ >= 4 )) || __cplusplus >= 201103)
    #define __Pyx_SET_CREAL(z,x) ((z).real(x))
    #define __Pyx_SET_CIMAG(z,y) ((z).imag(y))
#else
    #define __Pyx_SET_CREAL(z,x) __Pyx_CREAL(z) = (x)
    #define __Pyx_SET_CIMAG(z,y) __Pyx_CIMAG(z) = (y)
#endif

/* Arithmetic.proto */
#if CYTHON_CCOMPLEX
    #define __Pyx_c_eq_float(a, b)   ((a)==(b))
    #define __Pyx_c_sum_float(a, b)  ((a)+(b))
    #define __Pyx_c_diff_float(a, b) ((a)-(b))
    #define __Pyx_c_prod_float(a, b) ((a)*(b))
    #define __Pyx_c_quot_float(a, b) ((a)/(b))
    #define __Pyx_c_neg_float(a)     (-(a))
  #ifdef __cplusplus
    #define __Pyx_c_is_zero_float(z) ((z)==(float)0)
    #define __Pyx_c_conj_float(z)    (::std::conj(z))
    #if 1
        #define __Pyx_c_abs_float(z)     (::std::abs(z))
        #define __Pyx_c_pow_float(a, b)  (::std::pow(a, b))
    #endif
  #else
    #define __Pyx_c_is_zero_float(z) ((z)==0)
    #define __Pyx_c_conj_float(z)    (conjf(z))
    #if 1
        #define __Pyx_c_abs_float(z)     (cabsf(z))
        #define __Pyx_c_pow_float(a, b)  (cpowf(a, b))
    #endif
 #endif
#else
    static CYTHON_INLINE int __Pyx_c_eq_float(__pyx_t_float_complex, __pyx_t_float_complex);
    static CYTHON_INLINE __pyx_t_float_complex __Pyx_c_sum_float(__pyx_t_float_complex, __pyx_t_float_complex);
    static CYTHON_INLINE __pyx_t_float_complex __Pyx_c_diff_float(__pyx_t_float_complex, __pyx_t_float_complex);
    static CYTHON_INLINE __pyx_t_float_complex __Pyx_c_prod_float(__pyx_t_float_complex, __pyx_t_float_complex);
    static CYTHON_INLINE __pyx_t_float_complex __Pyx_c_quot_float(__pyx_t_float_complex, __pyx_t_float_complex);
    static CYTHON_INLINE __pyx_t_float_complex __Pyx_c_neg_float(__pyx_t_float_complex);
    static CYTHON_INLINE int __Pyx_c_is_zero_float(__pyx_t_float_complex);
    static CYTHON_INLINE __pyx_t_float_complex __Pyx_c_conj_float(__pyx_t_float_complex);
    #if 1
        static CYTHON_INLINE float __Pyx_c_abs_float(__pyx_t_float_complex);
        static CYTHON_INLINE __pyx_t_float_complex __Pyx_c_pow_float(__pyx_t_float_complex, __pyx_t_float_complex);
    #endif
#endif

/* Arithmetic.proto */
#if CYTHON_CCOMPLEX
    #define __Pyx_c_eq_double(a, b)   ((a)==(b))
    #define __Pyx_c_sum_double(a, b)  ((a)+(b))
    #define __Pyx_c_diff_double(a, b) ((a)-(b))
    #define __Pyx_c_prod_double(a, b) ((a)*(b))
    #define __Pyx_c_quot_double(a, b) ((a)/(b))
    #define __Pyx_c_neg_double(a)     (-(a))
  #ifdef __cplusplus
    #define __Pyx_c_is_zero_double(z) ((z)==(double)0)
    #define __Pyx_c_conj_double(z)    (::std::conj(z))
    #if 1
        #define __Pyx_c_abs_double(z)     (::std::abs(z))
        #define __Pyx_c_pow_double(a, b)  (::std::pow(a, b))
    #endif
  #else
    #define __Pyx_c_is_zero_double(z) ((z)==0)
    #define __Pyx_c_conj_double(z)    (conj(z))
    #if 1
        #define __Pyx_c_abs_double(z)     (cabs(z))
        #define __Pyx_c_pow_double(a, b)  (cpow(a, b))
    #endif
 #endif
#else
    static CYTHON_INLINE int __Pyx_c_eq_double(__pyx_t_double_complex, __pyx_t_double_complex);
    static CYTHON_INLINE __pyx_t_double_complex __Pyx_c_sum_double(__pyx_t_double_complex, __pyx_t_double_complex);
    static CYTHON_INLINE __pyx_t_double_complex __Pyx_c_diff_double(__pyx_t_double_complex, __pyx_t_double_complex);
    static CYTHON_INLINE __pyx_t_double_complex __Pyx_c_prod_double(__pyx_t_double_complex, __pyx_t_double_complex);
    static CYTHON_INLINE __pyx_t_double_complex __Pyx_c_quot_double(__pyx_t_double_complex, __pyx_t_double_complex);
    static CYTHON_INLINE __pyx_t_double_complex __Pyx_c_neg_double(__pyx_t_double_complex);
    static CYTHON_INLINE int __Pyx_c_is_zero_double(__pyx_t_double_complex);
    static CYTHON_INLINE __pyx_t_double_complex __Pyx_c_conj_double(__pyx_t_double_complex);
    #if 1
        static CYTHON_INLINE double __Pyx_c_abs_double(__pyx_t_double_complex);
        static CYTHON_INLINE __pyx_t_double_complex __Pyx_c_pow_double(__pyx_t_double_complex, __pyx_t_double_complex);
    #endif
#endif

/* CIntFromPy.proto */
static CYTHON_INLINE long __Pyx_PyInt_As_long(PyObject *);

/* CIntFromPy.proto */
static CYTHON_INLINE size_t __Pyx_PyInt_As_size_t(PyObject *);

/* CIntFromPy.proto */
static CYTHON_INLINE int __Pyx_PyInt_As_int(PyObject *);

/* FastTypeChecks.proto */
#if CYTHON_COMPILING_IN_CPYTHON
#define __Pyx_TypeCheck(obj, type) __Pyx_IsSubtype(Py_TYPE(obj), (PyTypeObject *)type)
static CYTHON_INLINE int __Pyx_IsSubtype(PyTypeObject *a, PyTypeObject *b);
static CYTHON_INLINE int __Pyx_PyErr_GivenExceptionMatches(PyObject *err, PyObject *type);
static CYTHON_INLINE int __Pyx_PyErr_GivenExceptionMatches2(PyObject *err, PyObject *type1, PyObject *type2);
#else
#define __Pyx_TypeCheck(obj, type) PyObject_TypeCheck(obj, (PyTypeObject *)type)
#define __Pyx_PyErr_GivenExceptionMatches(err, type) PyErr_GivenExceptionMatches(err, type)
#define __Pyx_PyErr_GivenExceptionMatches2(err, type1, type2) (PyErr_GivenExceptionMatches(err, type1) || PyErr_GivenExceptionMatches(err, type2))
#endif
#define __Pyx_PyException_Check(obj) __Pyx_TypeCheck(obj, PyExc_Exception)

/* CheckBinaryVersion.proto */
static int __Pyx_check_binary_version(void);

/* VoidPtrImport.proto */
static int __Pyx_ImportVoidPtr(PyObject *module, const char *name, void **p, const char *sig);

/* InitStrings.proto */
static int __Pyx_InitStrings(__Pyx_StringTabEntry *t);

static struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_FitNode *__pyx_f_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_7FitNode__create(struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitRecord *__pyx_v_fit, size_t __pyx_v_index); /* proto*/
static void __pyx_f_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_7FitNode__init_fields(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_FitNode *__pyx_v_self, PyObject *__pyx_v_experimental); /* proto*/
static int __pyx_f_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_7FitNode_isdisjoint(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_FitNode *__pyx_v_self, struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_FitNode *__pyx_v_other, CYTHON_UNUSED int __pyx_skip_dispatch); /* proto*/
static PyObject *__pyx_f_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_7FitNode_visit(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_FitNode *__pyx_v_self, struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_FitNode *__pyx_v_other, CYTHON_UNUSED int __pyx_skip_dispatch); /* proto*/
static void __pyx_f_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_23GreedySubgraphSelection__build_layers(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_GreedySubgraphSelection *__pyx_v_self); /* proto*/
static PyObject *__pyx_f_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_23GreedySubgraphSelection__select_best_subset(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_GreedySubgraphSelection *__pyx_v_self); /* proto*/
static PyObject *__pyx_f_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_23GreedySubgraphSelection_select(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_GreedySubgraphSelection *__pyx_v_self, CYTHON_UNUSED int __pyx_skip_dispatch); /* proto*/
static void __pyx_f_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_17ConnectedSubgraph__init_nodes(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_ConnectedSubgraph *__pyx_v_self, PyObject *__pyx_v_fits); /* proto*/
static void __pyx_f_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_17ConnectedSubgraph_populate_edges(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_ConnectedSubgraph *__pyx_v_self); /* proto*/
static PyObject *__pyx_f_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_17ConnectedSubgraph_find_heaviest_path(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_ConnectedSubgraph *__pyx_v_self, int __pyx_skip_dispatch, struct __pyx_opt_args_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_17ConnectedSubgraph_find_heaviest_path *__pyx_optional_args); /* proto*/

/* Module declarations from 'libc.string' */

/* Module declarations from 'libc.stdio' */

/* Module declarations from '__builtin__' */

/* Module declarations from 'cpython.type' */
static PyTypeObject *__pyx_ptype_7cpython_4type_type = 0;

/* Module declarations from 'cpython.buffer' */

/* Module declarations from 'cpython' */

/* Module declarations from 'cpython.object' */

/* Module declarations from 'cpython.list' */

/* Module declarations from 'cpython.tuple' */

/* Module declarations from 'ms_deisotope._c.peak_dependency_network.intervals' */
static PyTypeObject *__pyx_ptype_12ms_deisotope_2_c_23peak_dependency_network_9intervals_SpanningMixin = 0;
static PyTypeObject *__pyx_ptype_12ms_deisotope_2_c_23peak_dependency_network_9intervals_Interval = 0;
static PyTypeObject *__pyx_ptype_12ms_deisotope_2_c_23peak_dependency_network_9intervals_IntervalTreeNode = 0;

/* Module declarations from 'brainpy._c.composition' */
static PyTypeObject *__pyx_ptype_7brainpy_2_c_11composition_PyComposition = 0;
static PyObject **__pyx_vp_7brainpy_2_c_11composition_nist_mass = 0;
#define __pyx_v_7brainpy_2_c_11composition_nist_mass (*__pyx_vp_7brainpy_2_c_11composition_nist_mass)
static double *__pyx_vp_7brainpy_2_c_11composition_PROTON = 0;
#define __pyx_v_7brainpy_2_c_11composition_PROTON (*__pyx_vp_7brainpy_2_c_11composition_PROTON)
static struct __pyx_t_7brainpy_2_c_11composition_ElementHashTable **__pyx_vp_7brainpy_2_c_11composition__ElementTable = 0;
#define __pyx_v_7brainpy_2_c_11composition__ElementTable (*__pyx_vp_7brainpy_2_c_11composition__ElementTable)

/* Module declarations from 'brainpy._c.double_vector' */

/* Module declarations from 'brainpy._c.isotopic_constants' */
static size_t *__pyx_vp_7brainpy_2_c_18isotopic_constants_DEFAULT_ISOTOPIC_CONSTANTS_SIZE = 0;
#define __pyx_v_7brainpy_2_c_18isotopic_constants_DEFAULT_ISOTOPIC_CONSTANTS_SIZE (*__pyx_vp_7brainpy_2_c_18isotopic_constants_DEFAULT_ISOTOPIC_CONSTANTS_SIZE)

/* Module declarations from 'brainpy._c.isotopic_distribution' */
static PyTypeObject *__pyx_ptype_7brainpy_2_c_21isotopic_distribution_TheoreticalPeak = 0;

/* Module declarations from 'ms_peak_picker._c.peak_set' */
static PyTypeObject *__pyx_ptype_14ms_peak_picker_2_c_8peak_set_PeakBase = 0;
static PyTypeObject *__pyx_ptype_14ms_peak_picker_2_c_8peak_set_FittedPeak = 0;
static PyTypeObject *__pyx_ptype_14ms_peak_picker_2_c_8peak_set_PeakSet = 0;
static PyTypeObject *__pyx_ptype_14ms_peak_picker_2_c_8peak_set_PeakSetIndexed = 0;
static size_t *__pyx_vp_14ms_peak_picker_2_c_8peak_set_INTERVAL_INDEX_SIZE = 0;
#define __pyx_v_14ms_peak_picker_2_c_8peak_set_INTERVAL_INDEX_SIZE (*__pyx_vp_14ms_peak_picker_2_c_8peak_set_INTERVAL_INDEX_SIZE)

/* Module declarations from 'cython' */

/* Module declarations from 'cpython.ref' */

/* Module declarations from 'cpython.mem' */

/* Module declarations from 'numpy' */

/* Module declarations from 'numpy' */
static PyTypeObject *__pyx_ptype_5numpy_dtype = 0;
static PyTypeObject *__pyx_ptype_5numpy_flatiter = 0;
static PyTypeObject *__pyx_ptype_5numpy_broadcast = 0;
static PyTypeObject *__pyx_ptype_5numpy_ndarray = 0;
static PyTypeObject *__pyx_ptype_5numpy_ufunc = 0;

/* Module declarations from 'ms_peak_picker._c.peak_index' */
static PyTypeObject *__pyx_ptype_14ms_peak_picker_2_c_10peak_index_PeakIndex = 0;

/* Module declarations from 'ms_deisotope._c.averagine' */
static PyTypeObject *__pyx_ptype_12ms_deisotope_2_c_9averagine_Averagine = 0;
static PyTypeObject *__pyx_ptype_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern = 0;
static PyTypeObject *__pyx_ptype_12ms_deisotope_2_c_9averagine_AveragineCache = 0;
static double *__pyx_vp_12ms_deisotope_2_c_9averagine_PROTON = 0;
#define __pyx_v_12ms_deisotope_2_c_9averagine_PROTON (*__pyx_vp_12ms_deisotope_2_c_9averagine_PROTON)

/* Module declarations from 'ms_deisotope._c.deconvoluter_base' */
static PyTypeObject *__pyx_ptype_12ms_deisotope_2_c_17deconvoluter_base_DeconvoluterBase = 0;
static PyTypeObject *__pyx_ptype_12ms_deisotope_2_c_17deconvoluter_base_AveragineDeconvoluterBase = 0;
static PyTypeObject *__pyx_ptype_12ms_deisotope_2_c_17deconvoluter_base_MultiAveragineDeconvoluterBase = 0;
static PyTypeObject *__pyx_ptype_12ms_deisotope_2_c_17deconvoluter_base_ChargeIterator = 0;

/* Module declarations from 'ms_deisotope._c.scoring' */
static PyTypeObject *__pyx_ptype_12ms_deisotope_2_c_7scoring_IsotopicFitRecord = 0;
static PyTypeObject *__pyx_ptype_12ms_deisotope_2_c_7scoring_FitSelectorBase = 0;
static PyTypeObject *__pyx_ptype_12ms_deisotope_2_c_7scoring_IsotopicFitterBase = 0;
static PyTypeObject *__pyx_ptype_12ms_deisotope_2_c_7scoring_LeastSquaresFitter = 0;
static PyTypeObject *__pyx_ptype_12ms_deisotope_2_c_7scoring_GTestFitter = 0;
static PyTypeObject *__pyx_ptype_12ms_deisotope_2_c_7scoring_ScaledGTestFitter = 0;
static PyTypeObject *__pyx_ptype_12ms_deisotope_2_c_7scoring_MSDeconVFitter = 0;
static PyTypeObject *__pyx_ptype_12ms_deisotope_2_c_7scoring_PenalizedMSDeconVFitter = 0;
static PyTypeObject *__pyx_ptype_12ms_deisotope_2_c_7scoring_FunctionScorer = 0;
static PyTypeObject *__pyx_ptype_12ms_deisotope_2_c_7scoring_InterferenceDetection = 0;
static PyTypeObject *__pyx_ptype_12ms_deisotope_2_c_7scoring_DistinctPatternFitter = 0;
static PyTypeObject *__pyx_ptype_12ms_deisotope_2_c_7scoring_ScaledPenalizedMSDeconvFitter = 0;
static PyTypeObject *__pyx_ptype_12ms_deisotope_2_c_7scoring_DotProductFitter = 0;
static double *__pyx_vp_12ms_deisotope_2_c_7scoring_INFINITY = 0;
#define __pyx_v_12ms_deisotope_2_c_7scoring_INFINITY (*__pyx_vp_12ms_deisotope_2_c_7scoring_INFINITY)

/* Module declarations from 'cpython.set' */

/* Module declarations from 'ms_deisotope._c.peak_dependency_network.subgraph' */
static PyTypeObject *__pyx_ptype_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_FitNode = 0;
static PyTypeObject *__pyx_ptype_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_ConnectedSubgraph = 0;
static PyTypeObject *__pyx_ptype_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_GreedySubgraphSelection = 0;
static int __pyx_f_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_span_overlap(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_FitNode *, struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_FitNode *, int __pyx_skip_dispatch); /*proto*/
static int __pyx_f_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_peak_overlap(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_FitNode *, struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_FitNode *, int __pyx_skip_dispatch); /*proto*/
static PyObject *__pyx_f_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_layout_layers(PyObject *, int __pyx_skip_dispatch, struct __pyx_opt_args_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_layout_layers *__pyx_optional_args); /*proto*/
static PyObject *__pyx_f_12ms_deisotope_2_c_23peak_dependency_network_8subgraph___pyx_unpickle_FitNode__set_state(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_FitNode *, PyObject *); /*proto*/
static PyObject *__pyx_f_12ms_deisotope_2_c_23peak_dependency_network_8subgraph___pyx_unpickle_GreedySubgraphSelection__set_state(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_GreedySubgraphSelection *, PyObject *); /*proto*/
static PyObject *__pyx_f_12ms_deisotope_2_c_23peak_dependency_network_8subgraph___pyx_unpickle_ConnectedSubgraph__set_state(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_ConnectedSubgraph *, PyObject *); /*proto*/
#define __Pyx_MODULE_NAME "ms_deisotope._c.peak_dependency_network.subgraph"
extern int __pyx_module_is_main_ms_deisotope___c__peak_dependency_network__subgraph;
int __pyx_module_is_main_ms_deisotope___c__peak_dependency_network__subgraph = 0;

/* Implementation of 'ms_deisotope._c.peak_dependency_network.subgraph' */
static PyObject *__pyx_builtin_range;
static PyObject *__pyx_builtin_NotImplementedError;
static PyObject *__pyx_builtin_ImportError;
static const char __pyx_k_a[] = "a";
static const char __pyx_k_b[] = "b";
static const char __pyx_k_fit[] = "fit";
static const char __pyx_k_new[] = "__new__";
static const char __pyx_k_dict[] = "__dict__";
static const char __pyx_k_fits[] = "fits";
static const char __pyx_k_main[] = "__main__";
static const char __pyx_k_name[] = "__name__";
static const char __pyx_k_sort[] = "sort";
static const char __pyx_k_test[] = "__test__";
static const char __pyx_k_index[] = "index";
static const char __pyx_k_range[] = "range";
static const char __pyx_k_greedy[] = "greedy";
static const char __pyx_k_import[] = "__import__";
static const char __pyx_k_method[] = "method";
static const char __pyx_k_pickle[] = "pickle";
static const char __pyx_k_reduce[] = "__reduce__";
static const char __pyx_k_update[] = "update";
static const char __pyx_k_FitNode[] = "FitNode";
static const char __pyx_k_reverse[] = "reverse";
static const char __pyx_k_contains[] = "__contains__";
static const char __pyx_k_getstate[] = "__getstate__";
static const char __pyx_k_maximize[] = "maximize";
static const char __pyx_k_pyx_type[] = "__pyx_type";
static const char __pyx_k_setstate[] = "__setstate__";
static const char __pyx_k_subgraph[] = "subgraph";
static const char __pyx_k_FitNode_r[] = "FitNode(%r)";
static const char __pyx_k_envelopes[] = "envelopes";
static const char __pyx_k_pyx_state[] = "__pyx_state";
static const char __pyx_k_reduce_ex[] = "__reduce_ex__";
static const char __pyx_k_isdisjoint[] = "isdisjoint";
static const char __pyx_k_pyx_result[] = "__pyx_result";
static const char __pyx_k_pyx_vtable[] = "__pyx_vtable__";
static const char __pyx_k_ImportError[] = "ImportError";
static const char __pyx_k_PickleError[] = "PickleError";
static const char __pyx_k_pyx_checksum[] = "__pyx_checksum";
static const char __pyx_k_stringsource[] = "stringsource";
static const char __pyx_k_reduce_cython[] = "__reduce_cython__";
static const char __pyx_k_pyx_PickleError[] = "__pyx_PickleError";
static const char __pyx_k_setstate_cython[] = "__setstate_cython__";
static const char __pyx_k_ConnectedSubgraph[] = "ConnectedSubgraph";
static const char __pyx_k_cline_in_traceback[] = "cline_in_traceback";
static const char __pyx_k_find_heaviest_path[] = "find_heaviest_path";
static const char __pyx_k_NotImplementedError[] = "NotImplementedError";
static const char __pyx_k_pyx_unpickle_FitNode[] = "__pyx_unpickle_FitNode";
static const char __pyx_k_GreedySubgraphSelection[] = "GreedySubgraphSelection";
static const char __pyx_k_pyx_unpickle_ConnectedSubgraph[] = "__pyx_unpickle_ConnectedSubgraph";
static const char __pyx_k_pyx_unpickle_GreedySubgraphSel[] = "__pyx_unpickle_GreedySubgraphSelection";
static const char __pyx_k_ms_deisotope__c_peak_dependency[] = "ms_deisotope._c.peak_dependency_network.subgraph";
static const char __pyx_k_numpy_core_multiarray_failed_to[] = "numpy.core.multiarray failed to import";
static const char __pyx_k_Incompatible_checksums_s_vs_0x5c[] = "Incompatible checksums (%s vs 0x5c2d24d = (_layers, intervals, maximize))";
static const char __pyx_k_Incompatible_checksums_s_vs_0x67[] = "Incompatible checksums (%s vs 0x675da42 = (_hash, edges, end, fit, index, overlap_edges, peak_indices, score, start))";
static const char __pyx_k_Incompatible_checksums_s_vs_0xcb[] = "Incompatible checksums (%s vs 0xcb05c51 = (maximize, nodes))";
static const char __pyx_k_numpy_core_umath_failed_to_impor[] = "numpy.core.umath failed to import";
static PyObject *__pyx_n_s_ConnectedSubgraph;
static PyObject *__pyx_n_s_FitNode;
static PyObject *__pyx_kp_s_FitNode_r;
static PyObject *__pyx_n_s_GreedySubgraphSelection;
static PyObject *__pyx_n_s_ImportError;
static PyObject *__pyx_kp_s_Incompatible_checksums_s_vs_0x5c;
static PyObject *__pyx_kp_s_Incompatible_checksums_s_vs_0x67;
static PyObject *__pyx_kp_s_Incompatible_checksums_s_vs_0xcb;
static PyObject *__pyx_n_s_NotImplementedError;
static PyObject *__pyx_n_s_PickleError;
static PyObject *__pyx_n_s_a;
static PyObject *__pyx_n_s_b;
static PyObject *__pyx_n_s_cline_in_traceback;
static PyObject *__pyx_n_s_contains;
static PyObject *__pyx_n_s_dict;
static PyObject *__pyx_n_s_envelopes;
static PyObject *__pyx_n_s_find_heaviest_path;
static PyObject *__pyx_n_s_fit;
static PyObject *__pyx_n_s_fits;
static PyObject *__pyx_n_s_getstate;
static PyObject *__pyx_n_s_greedy;
static PyObject *__pyx_n_s_import;
static PyObject *__pyx_n_s_index;
static PyObject *__pyx_n_s_isdisjoint;
static PyObject *__pyx_n_s_main;
static PyObject *__pyx_n_s_maximize;
static PyObject *__pyx_n_s_method;
static PyObject *__pyx_n_s_ms_deisotope__c_peak_dependency;
static PyObject *__pyx_n_s_name;
static PyObject *__pyx_n_s_new;
static PyObject *__pyx_kp_s_numpy_core_multiarray_failed_to;
static PyObject *__pyx_kp_s_numpy_core_umath_failed_to_impor;
static PyObject *__pyx_n_s_pickle;
static PyObject *__pyx_n_s_pyx_PickleError;
static PyObject *__pyx_n_s_pyx_checksum;
static PyObject *__pyx_n_s_pyx_result;
static PyObject *__pyx_n_s_pyx_state;
static PyObject *__pyx_n_s_pyx_type;
static PyObject *__pyx_n_s_pyx_unpickle_ConnectedSubgraph;
static PyObject *__pyx_n_s_pyx_unpickle_FitNode;
static PyObject *__pyx_n_s_pyx_unpickle_GreedySubgraphSel;
static PyObject *__pyx_n_s_pyx_vtable;
static PyObject *__pyx_n_s_range;
static PyObject *__pyx_n_s_reduce;
static PyObject *__pyx_n_s_reduce_cython;
static PyObject *__pyx_n_s_reduce_ex;
static PyObject *__pyx_n_s_reverse;
static PyObject *__pyx_n_s_setstate;
static PyObject *__pyx_n_s_setstate_cython;
static PyObject *__pyx_n_s_sort;
static PyObject *__pyx_kp_s_stringsource;
static PyObject *__pyx_n_s_subgraph;
static PyObject *__pyx_n_s_test;
static PyObject *__pyx_n_s_update;
static int __pyx_pf_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_7FitNode___init__(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_FitNode *__pyx_v_self, struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitRecord *__pyx_v_fit, size_t __pyx_v_index); /* proto */
static Py_hash_t __pyx_pf_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_7FitNode_2__hash__(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_FitNode *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_7FitNode_4__eq__(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_FitNode *__pyx_v_self, struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_FitNode *__pyx_v_other); /* proto */
static PyObject *__pyx_pf_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_7FitNode_6__gt__(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_FitNode *__pyx_v_self, struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_FitNode *__pyx_v_other); /* proto */
static PyObject *__pyx_pf_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_7FitNode_8__lt__(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_FitNode *__pyx_v_self, struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_FitNode *__pyx_v_other); /* proto */
static PyObject *__pyx_pf_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_7FitNode_10__ne__(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_FitNode *__pyx_v_self, struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_FitNode *__pyx_v_other); /* proto */
static PyObject *__pyx_pf_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_7FitNode_12isdisjoint(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_FitNode *__pyx_v_self, struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_FitNode *__pyx_v_other); /* proto */
static PyObject *__pyx_pf_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_7FitNode_14visit(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_FitNode *__pyx_v_self, struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_FitNode *__pyx_v_other); /* proto */
static PyObject *__pyx_pf_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_7FitNode_16__repr__(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_FitNode *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_7FitNode_5index___get__(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_FitNode *__pyx_v_self); /* proto */
static int __pyx_pf_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_7FitNode_5index_2__set__(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_FitNode *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static PyObject *__pyx_pf_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_7FitNode_3fit___get__(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_FitNode *__pyx_v_self); /* proto */
static int __pyx_pf_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_7FitNode_3fit_2__set__(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_FitNode *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static int __pyx_pf_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_7FitNode_3fit_4__del__(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_FitNode *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_7FitNode_5edges___get__(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_FitNode *__pyx_v_self); /* proto */
static int __pyx_pf_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_7FitNode_5edges_2__set__(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_FitNode *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static int __pyx_pf_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_7FitNode_5edges_4__del__(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_FitNode *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_7FitNode_13overlap_edges___get__(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_FitNode *__pyx_v_self); /* proto */
static int __pyx_pf_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_7FitNode_13overlap_edges_2__set__(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_FitNode *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static int __pyx_pf_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_7FitNode_13overlap_edges_4__del__(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_FitNode *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_7FitNode_12peak_indices___get__(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_FitNode *__pyx_v_self); /* proto */
static int __pyx_pf_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_7FitNode_12peak_indices_2__set__(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_FitNode *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static int __pyx_pf_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_7FitNode_12peak_indices_4__del__(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_FitNode *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_7FitNode_5_hash___get__(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_FitNode *__pyx_v_self); /* proto */
static int __pyx_pf_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_7FitNode_5_hash_2__set__(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_FitNode *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static PyObject *__pyx_pf_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_7FitNode_5score___get__(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_FitNode *__pyx_v_self); /* proto */
static int __pyx_pf_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_7FitNode_5score_2__set__(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_FitNode *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static PyObject *__pyx_pf_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_7FitNode_18__reduce_cython__(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_FitNode *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_7FitNode_20__setstate_cython__(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_FitNode *__pyx_v_self, PyObject *__pyx_v___pyx_state); /* proto */
static PyObject *__pyx_pf_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_span_overlap(CYTHON_UNUSED PyObject *__pyx_self, struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_FitNode *__pyx_v_a, struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_FitNode *__pyx_v_b); /* proto */
static PyObject *__pyx_pf_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_2peak_overlap(CYTHON_UNUSED PyObject *__pyx_self, struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_FitNode *__pyx_v_a, struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_FitNode *__pyx_v_b); /* proto */
static PyObject *__pyx_pf_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_4layout_layers(CYTHON_UNUSED PyObject *__pyx_self, PyObject *__pyx_v_envelopes, int __pyx_v_maximize); /* proto */
static int __pyx_pf_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_23GreedySubgraphSelection___init__(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_GreedySubgraphSelection *__pyx_v_self, PyObject *__pyx_v_subgraph, int __pyx_v_maximize); /* proto */
static PyObject *__pyx_pf_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_23GreedySubgraphSelection_2select(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_GreedySubgraphSelection *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_23GreedySubgraphSelection_9intervals___get__(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_GreedySubgraphSelection *__pyx_v_self); /* proto */
static int __pyx_pf_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_23GreedySubgraphSelection_9intervals_2__set__(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_GreedySubgraphSelection *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static int __pyx_pf_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_23GreedySubgraphSelection_9intervals_4__del__(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_GreedySubgraphSelection *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_23GreedySubgraphSelection_7_layers___get__(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_GreedySubgraphSelection *__pyx_v_self); /* proto */
static int __pyx_pf_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_23GreedySubgraphSelection_7_layers_2__set__(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_GreedySubgraphSelection *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static int __pyx_pf_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_23GreedySubgraphSelection_7_layers_4__del__(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_GreedySubgraphSelection *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_23GreedySubgraphSelection_8maximize___get__(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_GreedySubgraphSelection *__pyx_v_self); /* proto */
static int __pyx_pf_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_23GreedySubgraphSelection_8maximize_2__set__(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_GreedySubgraphSelection *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static PyObject *__pyx_pf_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_23GreedySubgraphSelection_4__reduce_cython__(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_GreedySubgraphSelection *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_23GreedySubgraphSelection_6__setstate_cython__(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_GreedySubgraphSelection *__pyx_v_self, PyObject *__pyx_v___pyx_state); /* proto */
static int __pyx_pf_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_17ConnectedSubgraph___init__(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_ConnectedSubgraph *__pyx_v_self, PyObject *__pyx_v_fits, int __pyx_v_maximize); /* proto */
static PyObject *__pyx_pf_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_17ConnectedSubgraph_2__getitem__(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_ConnectedSubgraph *__pyx_v_self, PyObject *__pyx_v_i); /* proto */
static PyObject *__pyx_pf_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_17ConnectedSubgraph_4__iter__(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_ConnectedSubgraph *__pyx_v_self); /* proto */
static Py_ssize_t __pyx_pf_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_17ConnectedSubgraph_6__len__(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_ConnectedSubgraph *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_17ConnectedSubgraph_8find_heaviest_path(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_ConnectedSubgraph *__pyx_v_self, PyObject *__pyx_v_method); /* proto */
static PyObject *__pyx_pf_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_17ConnectedSubgraph_5nodes___get__(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_ConnectedSubgraph *__pyx_v_self); /* proto */
static int __pyx_pf_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_17ConnectedSubgraph_5nodes_2__set__(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_ConnectedSubgraph *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static int __pyx_pf_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_17ConnectedSubgraph_5nodes_4__del__(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_ConnectedSubgraph *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_17ConnectedSubgraph_8maximize___get__(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_ConnectedSubgraph *__pyx_v_self); /* proto */
static int __pyx_pf_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_17ConnectedSubgraph_8maximize_2__set__(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_ConnectedSubgraph *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static PyObject *__pyx_pf_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_17ConnectedSubgraph_10__reduce_cython__(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_ConnectedSubgraph *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_17ConnectedSubgraph_12__setstate_cython__(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_ConnectedSubgraph *__pyx_v_self, PyObject *__pyx_v___pyx_state); /* proto */
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static PyObject *__pyx_pf_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_8__pyx_unpickle_GreedySubgraphSelection(CYTHON_UNUSED PyObject *__pyx_self, PyObject *__pyx_v___pyx_type, long __pyx_v___pyx_checksum, PyObject *__pyx_v___pyx_state); /* proto */
static PyObject *__pyx_pf_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_10__pyx_unpickle_ConnectedSubgraph(CYTHON_UNUSED PyObject *__pyx_self, PyObject *__pyx_v___pyx_type, long __pyx_v___pyx_checksum, PyObject *__pyx_v___pyx_state); /* proto */
static PyObject *__pyx_tp_new_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_FitNode(PyTypeObject *t, PyObject *a, PyObject *k); /*proto*/
static PyObject *__pyx_tp_new_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_ConnectedSubgraph(PyTypeObject *t, PyObject *a, PyObject *k); /*proto*/
static PyObject *__pyx_tp_new_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_GreedySubgraphSelection(PyTypeObject *t, PyObject *a, PyObject *k); /*proto*/
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static void __pyx_tp_dealloc_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_FitNode(PyObject *o) {
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static PyObject *__pyx_getprop_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_7FitNode_score(PyObject *o, CYTHON_UNUSED void *x) {
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static int __pyx_setprop_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_7FitNode_score(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
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  0, /*tp_as_sequence*/
  0, /*tp_as_mapping*/
  __pyx_pw_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_7FitNode_3__hash__, /*tp_hash*/
  0, /*tp_call*/
  0, /*tp_str*/
  0, /*tp_getattro*/
  0, /*tp_setattro*/
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  Py_TPFLAGS_DEFAULT|Py_TPFLAGS_HAVE_VERSION_TAG|Py_TPFLAGS_CHECKTYPES|Py_TPFLAGS_HAVE_NEWBUFFER|Py_TPFLAGS_HAVE_GC, /*tp_flags*/
  "FitNode(IsotopicFitRecord fit, size_t index=-1)", /*tp_doc*/
  __pyx_tp_traverse_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_FitNode, /*tp_traverse*/
  __pyx_tp_clear_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_FitNode, /*tp_clear*/
  __pyx_tp_richcompare_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_FitNode, /*tp_richcompare*/
  0, /*tp_weaklistoffset*/
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  0, /*tp_iternext*/
  __pyx_methods_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_FitNode, /*tp_methods*/
  0, /*tp_members*/
  __pyx_getsets_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_FitNode, /*tp_getset*/
  0, /*tp_base*/
  0, /*tp_dict*/
  0, /*tp_descr_get*/
  0, /*tp_descr_set*/
  0, /*tp_dictoffset*/
  __pyx_pw_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_7FitNode_1__init__, /*tp_init*/
  0, /*tp_alloc*/
  __pyx_tp_new_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_FitNode, /*tp_new*/
  0, /*tp_free*/
  0, /*tp_is_gc*/
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  0, /*tp_cache*/
  0, /*tp_subclasses*/
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  0, /*tp_del*/
  0, /*tp_version_tag*/
  #if PY_VERSION_HEX >= 0x030400a1
  0, /*tp_finalize*/
  #endif
  #if PY_VERSION_HEX >= 0x030800b1
  0, /*tp_vectorcall*/
  #endif
  #if PY_VERSION_HEX >= 0x030800b4 && PY_VERSION_HEX < 0x03090000
  0, /*tp_print*/
  #endif
};
static struct __pyx_vtabstruct_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_ConnectedSubgraph __pyx_vtable_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_ConnectedSubgraph;

static struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_ConnectedSubgraph *__pyx_freelist_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_ConnectedSubgraph[5];
static int __pyx_freecount_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_ConnectedSubgraph = 0;

static PyObject *__pyx_tp_new_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_ConnectedSubgraph(PyTypeObject *t, CYTHON_UNUSED PyObject *a, CYTHON_UNUSED PyObject *k) {
  struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_ConnectedSubgraph *p;
  PyObject *o;
  if (CYTHON_COMPILING_IN_CPYTHON && likely((__pyx_freecount_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_ConnectedSubgraph > 0) & (t->tp_basicsize == sizeof(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_ConnectedSubgraph)) & ((t->tp_flags & (Py_TPFLAGS_IS_ABSTRACT | Py_TPFLAGS_HEAPTYPE)) == 0))) {
    o = (PyObject*)__pyx_freelist_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_ConnectedSubgraph[--__pyx_freecount_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_ConnectedSubgraph];
    memset(o, 0, sizeof(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_ConnectedSubgraph));
    (void) PyObject_INIT(o, t);
    PyObject_GC_Track(o);
  } else {
    if (likely((t->tp_flags & Py_TPFLAGS_IS_ABSTRACT) == 0)) {
      o = (*t->tp_alloc)(t, 0);
    } else {
      o = (PyObject *) PyBaseObject_Type.tp_new(t, __pyx_empty_tuple, 0);
    }
    if (unlikely(!o)) return 0;
  }
  p = ((struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_ConnectedSubgraph *)o);
  p->__pyx_vtab = __pyx_vtabptr_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_ConnectedSubgraph;
  p->nodes = ((PyObject*)Py_None); Py_INCREF(Py_None);
  return o;
}

static void __pyx_tp_dealloc_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_ConnectedSubgraph(PyObject *o) {
  struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_ConnectedSubgraph *p = (struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_ConnectedSubgraph *)o;
  #if CYTHON_USE_TP_FINALIZE
  if (unlikely(PyType_HasFeature(Py_TYPE(o), Py_TPFLAGS_HAVE_FINALIZE) && Py_TYPE(o)->tp_finalize) && !_PyGC_FINALIZED(o)) {
    if (PyObject_CallFinalizerFromDealloc(o)) return;
  }
  #endif
  PyObject_GC_UnTrack(o);
  Py_CLEAR(p->nodes);
  if (CYTHON_COMPILING_IN_CPYTHON && ((__pyx_freecount_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_ConnectedSubgraph < 5) & (Py_TYPE(o)->tp_basicsize == sizeof(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_ConnectedSubgraph)) & ((Py_TYPE(o)->tp_flags & (Py_TPFLAGS_IS_ABSTRACT | Py_TPFLAGS_HEAPTYPE)) == 0))) {
    __pyx_freelist_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_ConnectedSubgraph[__pyx_freecount_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_ConnectedSubgraph++] = ((struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_ConnectedSubgraph *)o);
  } else {
    (*Py_TYPE(o)->tp_free)(o);
  }
}

static int __pyx_tp_traverse_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_ConnectedSubgraph(PyObject *o, visitproc v, void *a) {
  int e;
  struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_ConnectedSubgraph *p = (struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_ConnectedSubgraph *)o;
  if (p->nodes) {
    e = (*v)(p->nodes, a); if (e) return e;
  }
  return 0;
}

static int __pyx_tp_clear_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_ConnectedSubgraph(PyObject *o) {
  PyObject* tmp;
  struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_ConnectedSubgraph *p = (struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_ConnectedSubgraph *)o;
  tmp = ((PyObject*)p->nodes);
  p->nodes = ((PyObject*)Py_None); Py_INCREF(Py_None);
  Py_XDECREF(tmp);
  return 0;
}
static PyObject *__pyx_sq_item_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_ConnectedSubgraph(PyObject *o, Py_ssize_t i) {
  PyObject *r;
  PyObject *x = PyInt_FromSsize_t(i); if(!x) return 0;
  r = Py_TYPE(o)->tp_as_mapping->mp_subscript(o, x);
  Py_DECREF(x);
  return r;
}

static PyObject *__pyx_getprop_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_17ConnectedSubgraph_nodes(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_17ConnectedSubgraph_5nodes_1__get__(o);
}

static int __pyx_setprop_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_17ConnectedSubgraph_nodes(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
  if (v) {
    return __pyx_pw_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_17ConnectedSubgraph_5nodes_3__set__(o, v);
  }
  else {
    return __pyx_pw_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_17ConnectedSubgraph_5nodes_5__del__(o);
  }
}

static PyObject *__pyx_getprop_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_17ConnectedSubgraph_maximize(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_17ConnectedSubgraph_8maximize_1__get__(o);
}

static int __pyx_setprop_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_17ConnectedSubgraph_maximize(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
  if (v) {
    return __pyx_pw_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_17ConnectedSubgraph_8maximize_3__set__(o, v);
  }
  else {
    PyErr_SetString(PyExc_NotImplementedError, "__del__");
    return -1;
  }
}

static PyMethodDef __pyx_methods_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_ConnectedSubgraph[] = {
  {"find_heaviest_path", (PyCFunction)(void*)(PyCFunctionWithKeywords)__pyx_pw_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_17ConnectedSubgraph_9find_heaviest_path, METH_VARARGS|METH_KEYWORDS, __pyx_doc_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_17ConnectedSubgraph_8find_heaviest_path},
  {"__reduce_cython__", (PyCFunction)__pyx_pw_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_17ConnectedSubgraph_11__reduce_cython__, METH_NOARGS, __pyx_doc_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_17ConnectedSubgraph_10__reduce_cython__},
  {"__setstate_cython__", (PyCFunction)__pyx_pw_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_17ConnectedSubgraph_13__setstate_cython__, METH_O, __pyx_doc_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_17ConnectedSubgraph_12__setstate_cython__},
  {0, 0, 0, 0}
};

static struct PyGetSetDef __pyx_getsets_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_ConnectedSubgraph[] = {
  {(char *)"nodes", __pyx_getprop_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_17ConnectedSubgraph_nodes, __pyx_setprop_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_17ConnectedSubgraph_nodes, (char *)"nodes: tuple", 0},
  {(char *)"maximize", __pyx_getprop_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_17ConnectedSubgraph_maximize, __pyx_setprop_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_17ConnectedSubgraph_maximize, (char *)"maximize: 'bool'", 0},
  {0, 0, 0, 0, 0}
};

static PySequenceMethods __pyx_tp_as_sequence_ConnectedSubgraph = {
  __pyx_pw_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_17ConnectedSubgraph_7__len__, /*sq_length*/
  0, /*sq_concat*/
  0, /*sq_repeat*/
  __pyx_sq_item_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_ConnectedSubgraph, /*sq_item*/
  0, /*sq_slice*/
  0, /*sq_ass_item*/
  0, /*sq_ass_slice*/
  0, /*sq_contains*/
  0, /*sq_inplace_concat*/
  0, /*sq_inplace_repeat*/
};

static PyMappingMethods __pyx_tp_as_mapping_ConnectedSubgraph = {
  __pyx_pw_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_17ConnectedSubgraph_7__len__, /*mp_length*/
  __pyx_pw_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_17ConnectedSubgraph_3__getitem__, /*mp_subscript*/
  0, /*mp_ass_subscript*/
};

static PyTypeObject __pyx_type_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_ConnectedSubgraph = {
  PyVarObject_HEAD_INIT(0, 0)
  "ms_deisotope._c.peak_dependency_network.subgraph.ConnectedSubgraph", /*tp_name*/
  sizeof(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_ConnectedSubgraph), /*tp_basicsize*/
  0, /*tp_itemsize*/
  __pyx_tp_dealloc_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_ConnectedSubgraph, /*tp_dealloc*/
  #if PY_VERSION_HEX < 0x030800b4
  0, /*tp_print*/
  #endif
  #if PY_VERSION_HEX >= 0x030800b4
  0, /*tp_vectorcall_offset*/
  #endif
  0, /*tp_getattr*/
  0, /*tp_setattr*/
  #if PY_MAJOR_VERSION < 3
  0, /*tp_compare*/
  #endif
  #if PY_MAJOR_VERSION >= 3
  0, /*tp_as_async*/
  #endif
  0, /*tp_repr*/
  0, /*tp_as_number*/
  &__pyx_tp_as_sequence_ConnectedSubgraph, /*tp_as_sequence*/
  &__pyx_tp_as_mapping_ConnectedSubgraph, /*tp_as_mapping*/
  0, /*tp_hash*/
  0, /*tp_call*/
  0, /*tp_str*/
  0, /*tp_getattro*/
  0, /*tp_setattro*/
  0, /*tp_as_buffer*/
  Py_TPFLAGS_DEFAULT|Py_TPFLAGS_HAVE_VERSION_TAG|Py_TPFLAGS_CHECKTYPES|Py_TPFLAGS_HAVE_NEWBUFFER|Py_TPFLAGS_BASETYPE|Py_TPFLAGS_HAVE_GC, /*tp_flags*/
  "ConnectedSubgraph(fits, bool maximize=True)", /*tp_doc*/
  __pyx_tp_traverse_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_ConnectedSubgraph, /*tp_traverse*/
  __pyx_tp_clear_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_ConnectedSubgraph, /*tp_clear*/
  0, /*tp_richcompare*/
  0, /*tp_weaklistoffset*/
  __pyx_pw_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_17ConnectedSubgraph_5__iter__, /*tp_iter*/
  0, /*tp_iternext*/
  __pyx_methods_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_ConnectedSubgraph, /*tp_methods*/
  0, /*tp_members*/
  __pyx_getsets_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_ConnectedSubgraph, /*tp_getset*/
  0, /*tp_base*/
  0, /*tp_dict*/
  0, /*tp_descr_get*/
  0, /*tp_descr_set*/
  0, /*tp_dictoffset*/
  __pyx_pw_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_17ConnectedSubgraph_1__init__, /*tp_init*/
  0, /*tp_alloc*/
  __pyx_tp_new_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_ConnectedSubgraph, /*tp_new*/
  0, /*tp_free*/
  0, /*tp_is_gc*/
  0, /*tp_bases*/
  0, /*tp_mro*/
  0, /*tp_cache*/
  0, /*tp_subclasses*/
  0, /*tp_weaklist*/
  0, /*tp_del*/
  0, /*tp_version_tag*/
  #if PY_VERSION_HEX >= 0x030400a1
  0, /*tp_finalize*/
  #endif
  #if PY_VERSION_HEX >= 0x030800b1
  0, /*tp_vectorcall*/
  #endif
  #if PY_VERSION_HEX >= 0x030800b4 && PY_VERSION_HEX < 0x03090000
  0, /*tp_print*/
  #endif
};
static struct __pyx_vtabstruct_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_GreedySubgraphSelection __pyx_vtable_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_GreedySubgraphSelection;

static struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_GreedySubgraphSelection *__pyx_freelist_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_GreedySubgraphSelection[5];
static int __pyx_freecount_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_GreedySubgraphSelection = 0;

static PyObject *__pyx_tp_new_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_GreedySubgraphSelection(PyTypeObject *t, CYTHON_UNUSED PyObject *a, CYTHON_UNUSED PyObject *k) {
  struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_GreedySubgraphSelection *p;
  PyObject *o;
  if (CYTHON_COMPILING_IN_CPYTHON && likely((__pyx_freecount_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_GreedySubgraphSelection > 0) & (t->tp_basicsize == sizeof(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_GreedySubgraphSelection)))) {
    o = (PyObject*)__pyx_freelist_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_GreedySubgraphSelection[--__pyx_freecount_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_GreedySubgraphSelection];
    memset(o, 0, sizeof(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_GreedySubgraphSelection));
    (void) PyObject_INIT(o, t);
    PyObject_GC_Track(o);
  } else {
    o = (*t->tp_alloc)(t, 0);
    if (unlikely(!o)) return 0;
  }
  p = ((struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_GreedySubgraphSelection *)o);
  p->__pyx_vtab = __pyx_vtabptr_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_GreedySubgraphSelection;
  p->intervals = ((PyObject*)Py_None); Py_INCREF(Py_None);
  p->_layers = ((PyObject*)Py_None); Py_INCREF(Py_None);
  return o;
}

static void __pyx_tp_dealloc_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_GreedySubgraphSelection(PyObject *o) {
  struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_GreedySubgraphSelection *p = (struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_GreedySubgraphSelection *)o;
  PyObject_GC_UnTrack(o);
  Py_CLEAR(p->intervals);
  Py_CLEAR(p->_layers);
  if (CYTHON_COMPILING_IN_CPYTHON && ((__pyx_freecount_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_GreedySubgraphSelection < 5) & (Py_TYPE(o)->tp_basicsize == sizeof(struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_GreedySubgraphSelection)))) {
    __pyx_freelist_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_GreedySubgraphSelection[__pyx_freecount_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_GreedySubgraphSelection++] = ((struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_GreedySubgraphSelection *)o);
  } else {
    (*Py_TYPE(o)->tp_free)(o);
  }
}

static int __pyx_tp_traverse_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_GreedySubgraphSelection(PyObject *o, visitproc v, void *a) {
  int e;
  struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_GreedySubgraphSelection *p = (struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_GreedySubgraphSelection *)o;
  if (p->intervals) {
    e = (*v)(p->intervals, a); if (e) return e;
  }
  if (p->_layers) {
    e = (*v)(p->_layers, a); if (e) return e;
  }
  return 0;
}

static int __pyx_tp_clear_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_GreedySubgraphSelection(PyObject *o) {
  PyObject* tmp;
  struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_GreedySubgraphSelection *p = (struct __pyx_obj_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_GreedySubgraphSelection *)o;
  tmp = ((PyObject*)p->intervals);
  p->intervals = ((PyObject*)Py_None); Py_INCREF(Py_None);
  Py_XDECREF(tmp);
  tmp = ((PyObject*)p->_layers);
  p->_layers = ((PyObject*)Py_None); Py_INCREF(Py_None);
  Py_XDECREF(tmp);
  return 0;
}

static PyObject *__pyx_getprop_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_23GreedySubgraphSelection_intervals(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_23GreedySubgraphSelection_9intervals_1__get__(o);
}

static int __pyx_setprop_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_23GreedySubgraphSelection_intervals(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
  if (v) {
    return __pyx_pw_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_23GreedySubgraphSelection_9intervals_3__set__(o, v);
  }
  else {
    return __pyx_pw_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_23GreedySubgraphSelection_9intervals_5__del__(o);
  }
}

static PyObject *__pyx_getprop_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_23GreedySubgraphSelection__layers(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_23GreedySubgraphSelection_7_layers_1__get__(o);
}

static int __pyx_setprop_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_23GreedySubgraphSelection__layers(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
  if (v) {
    return __pyx_pw_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_23GreedySubgraphSelection_7_layers_3__set__(o, v);
  }
  else {
    return __pyx_pw_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_23GreedySubgraphSelection_7_layers_5__del__(o);
  }
}

static PyObject *__pyx_getprop_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_23GreedySubgraphSelection_maximize(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_23GreedySubgraphSelection_8maximize_1__get__(o);
}

static int __pyx_setprop_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_23GreedySubgraphSelection_maximize(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
  if (v) {
    return __pyx_pw_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_23GreedySubgraphSelection_8maximize_3__set__(o, v);
  }
  else {
    PyErr_SetString(PyExc_NotImplementedError, "__del__");
    return -1;
  }
}

static PyMethodDef __pyx_methods_12ms_deisotope_2_c_23peak_dependency_network_8subgraph_GreedySubgraphSelection[] = {
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}

/* ArgTypeTest */
static int __Pyx__ArgTypeTest(PyObject *obj, PyTypeObject *type, const char *name, int exact)
{
    if (unlikely(!type)) {
        PyErr_SetString(PyExc_SystemError, "Missing type object");
        return 0;
    }
    else if (exact) {
        #if PY_MAJOR_VERSION == 2
        if ((type == &PyBaseString_Type) && likely(__Pyx_PyBaseString_CheckExact(obj))) return 1;
        #endif
    }
    else {
        if (likely(__Pyx_TypeCheck(obj, type))) return 1;
    }
    PyErr_Format(PyExc_TypeError,
        "Argument '%.200s' has incorrect type (expected %.200s, got %.200s)",
        name, type->tp_name, Py_TYPE(obj)->tp_name);
    return 0;
}

/* None */
static CYTHON_INLINE void __Pyx_RaiseUnboundLocalError(const char *varname) {
    PyErr_Format(PyExc_UnboundLocalError, "local variable '%s' referenced before assignment", varname);
}

/* PyErrFetchRestore */
#if CYTHON_FAST_THREAD_STATE
static CYTHON_INLINE void __Pyx_ErrRestoreInState(PyThreadState *tstate, PyObject *type, PyObject *value, PyObject *tb) {
    PyObject *tmp_type, *tmp_value, *tmp_tb;
    tmp_type = tstate->curexc_type;
    tmp_value = tstate->curexc_value;
    tmp_tb = tstate->curexc_traceback;
    tstate->curexc_type = type;
    tstate->curexc_value = value;
    tstate->curexc_traceback = tb;
    Py_XDECREF(tmp_type);
    Py_XDECREF(tmp_value);
    Py_XDECREF(tmp_tb);
}
static CYTHON_INLINE void __Pyx_ErrFetchInState(PyThreadState *tstate, PyObject **type, PyObject **value, PyObject **tb) {
    *type = tstate->curexc_type;
    *value = tstate->curexc_value;
    *tb = tstate->curexc_traceback;
    tstate->curexc_type = 0;
    tstate->curexc_value = 0;
    tstate->curexc_traceback = 0;
}
#endif

/* WriteUnraisableException */
static void __Pyx_WriteUnraisable(const char *name, CYTHON_UNUSED int clineno,
                                  CYTHON_UNUSED int lineno, CYTHON_UNUSED const char *filename,
                                  int full_traceback, CYTHON_UNUSED int nogil) {
    PyObject *old_exc, *old_val, *old_tb;
    PyObject *ctx;
    __Pyx_PyThreadState_declare
#ifdef WITH_THREAD
    PyGILState_STATE state;
    if (nogil)
        state = PyGILState_Ensure();
#ifdef _MSC_VER
    else state = (PyGILState_STATE)-1;
#endif
#endif
    __Pyx_PyThreadState_assign
    __Pyx_ErrFetch(&old_exc, &old_val, &old_tb);
    if (full_traceback) {
        Py_XINCREF(old_exc);
        Py_XINCREF(old_val);
        Py_XINCREF(old_tb);
        __Pyx_ErrRestore(old_exc, old_val, old_tb);
        PyErr_PrintEx(1);
    }
    #if PY_MAJOR_VERSION < 3
    ctx = PyString_FromString(name);
    #else
    ctx = PyUnicode_FromString(name);
    #endif
    __Pyx_ErrRestore(old_exc, old_val, old_tb);
    if (!ctx) {
        PyErr_WriteUnraisable(Py_None);
    } else {
        PyErr_WriteUnraisable(ctx);
        Py_DECREF(ctx);
    }
#ifdef WITH_THREAD
    if (nogil)
        PyGILState_Release(state);
#endif
}

/* PyCFunctionFastCall */
#if CYTHON_FAST_PYCCALL
static CYTHON_INLINE PyObject * __Pyx_PyCFunction_FastCall(PyObject *func_obj, PyObject **args, Py_ssize_t nargs) {
    PyCFunctionObject *func = (PyCFunctionObject*)func_obj;
    PyCFunction meth = PyCFunction_GET_FUNCTION(func);
    PyObject *self = PyCFunction_GET_SELF(func);
    int flags = PyCFunction_GET_FLAGS(func);
    assert(PyCFunction_Check(func));
    assert(METH_FASTCALL == (flags & ~(METH_CLASS | METH_STATIC | METH_COEXIST | METH_KEYWORDS | METH_STACKLESS)));
    assert(nargs >= 0);
    assert(nargs == 0 || args != NULL);
    /* _PyCFunction_FastCallDict() must not be called with an exception set,
       because it may clear it (directly or indirectly) and so the
       caller loses its exception */
    assert(!PyErr_Occurred());
    if ((PY_VERSION_HEX < 0x030700A0) || unlikely(flags & METH_KEYWORDS)) {
        return (*((__Pyx_PyCFunctionFastWithKeywords)(void*)meth)) (self, args, nargs, NULL);
    } else {
        return (*((__Pyx_PyCFunctionFast)(void*)meth)) (self, args, nargs);
    }
}
#endif

/* PyFunctionFastCall */
#if CYTHON_FAST_PYCALL
static PyObject* __Pyx_PyFunction_FastCallNoKw(PyCodeObject *co, PyObject **args, Py_ssize_t na,
                                               PyObject *globals) {
    PyFrameObject *f;
    PyThreadState *tstate = __Pyx_PyThreadState_Current;
    PyObject **fastlocals;
    Py_ssize_t i;
    PyObject *result;
    assert(globals != NULL);
    /* XXX Perhaps we should create a specialized
       PyFrame_New() that doesn't take locals, but does
       take builtins without sanity checking them.
       */
    assert(tstate != NULL);
    f = PyFrame_New(tstate, co, globals, NULL);
    if (f == NULL) {
        return NULL;
    }
    fastlocals = __Pyx_PyFrame_GetLocalsplus(f);
    for (i = 0; i < na; i++) {
        Py_INCREF(*args);
        fastlocals[i] = *args++;
    }
    result = PyEval_EvalFrameEx(f,0);
    ++tstate->recursion_depth;
    Py_DECREF(f);
    --tstate->recursion_depth;
    return result;
}
#if 1 || PY_VERSION_HEX < 0x030600B1
static PyObject *__Pyx_PyFunction_FastCallDict(PyObject *func, PyObject **args, Py_ssize_t nargs, PyObject *kwargs) {
    PyCodeObject *co = (PyCodeObject *)PyFunction_GET_CODE(func);
    PyObject *globals = PyFunction_GET_GLOBALS(func);
    PyObject *argdefs = PyFunction_GET_DEFAULTS(func);
    PyObject *closure;
#if PY_MAJOR_VERSION >= 3
    PyObject *kwdefs;
#endif
    PyObject *kwtuple, **k;
    PyObject **d;
    Py_ssize_t nd;
    Py_ssize_t nk;
    PyObject *result;
    assert(kwargs == NULL || PyDict_Check(kwargs));
    nk = kwargs ? PyDict_Size(kwargs) : 0;
    if (Py_EnterRecursiveCall((char*)" while calling a Python object")) {
        return NULL;
    }
    if (
#if PY_MAJOR_VERSION >= 3
            co->co_kwonlyargcount == 0 &&
#endif
            likely(kwargs == NULL || nk == 0) &&
            co->co_flags == (CO_OPTIMIZED | CO_NEWLOCALS | CO_NOFREE)) {
        if (argdefs == NULL && co->co_argcount == nargs) {
            result = __Pyx_PyFunction_FastCallNoKw(co, args, nargs, globals);
            goto done;
        }
        else if (nargs == 0 && argdefs != NULL
                 && co->co_argcount == Py_SIZE(argdefs)) {
            /* function called with no arguments, but all parameters have
               a default value: use default values as arguments .*/
            args = &PyTuple_GET_ITEM(argdefs, 0);
            result =__Pyx_PyFunction_FastCallNoKw(co, args, Py_SIZE(argdefs), globals);
            goto done;
        }
    }
    if (kwargs != NULL) {
        Py_ssize_t pos, i;
        kwtuple = PyTuple_New(2 * nk);
        if (kwtuple == NULL) {
            result = NULL;
            goto done;
        }
        k = &PyTuple_GET_ITEM(kwtuple, 0);
        pos = i = 0;
        while (PyDict_Next(kwargs, &pos, &k[i], &k[i+1])) {
            Py_INCREF(k[i]);
            Py_INCREF(k[i+1]);
            i += 2;
        }
        nk = i / 2;
    }
    else {
        kwtuple = NULL;
        k = NULL;
    }
    closure = PyFunction_GET_CLOSURE(func);
#if PY_MAJOR_VERSION >= 3
    kwdefs = PyFunction_GET_KW_DEFAULTS(func);
#endif
    if (argdefs != NULL) {
        d = &PyTuple_GET_ITEM(argdefs, 0);
        nd = Py_SIZE(argdefs);
    }
    else {
        d = NULL;
        nd = 0;
    }
#if PY_MAJOR_VERSION >= 3
    result = PyEval_EvalCodeEx((PyObject*)co, globals, (PyObject *)NULL,
                               args, (int)nargs,
                               k, (int)nk,
                               d, (int)nd, kwdefs, closure);
#else
    result = PyEval_EvalCodeEx(co, globals, (PyObject *)NULL,
                               args, (int)nargs,
                               k, (int)nk,
                               d, (int)nd, closure);
#endif
    Py_XDECREF(kwtuple);
done:
    Py_LeaveRecursiveCall();
    return result;
}
#endif
#endif

/* PyObjectCall */
#if CYTHON_COMPILING_IN_CPYTHON
static CYTHON_INLINE PyObject* __Pyx_PyObject_Call(PyObject *func, PyObject *arg, PyObject *kw) {
    PyObject *result;
    ternaryfunc call = func->ob_type->tp_call;
    if (unlikely(!call))
        return PyObject_Call(func, arg, kw);
    if (unlikely(Py_EnterRecursiveCall((char*)" while calling a Python object")))
        return NULL;
    result = (*call)(func, arg, kw);
    Py_LeaveRecursiveCall();
    if (unlikely(!result) && unlikely(!PyErr_Occurred())) {
        PyErr_SetString(
            PyExc_SystemError,
            "NULL result without error in PyObject_Call");
    }
    return result;
}
#endif

/* PyObjectCall2Args */
static CYTHON_UNUSED PyObject* __Pyx_PyObject_Call2Args(PyObject* function, PyObject* arg1, PyObject* arg2) {
    PyObject *args, *result = NULL;
    #if CYTHON_FAST_PYCALL
    if (PyFunction_Check(function)) {
        PyObject *args[2] = {arg1, arg2};
        return __Pyx_PyFunction_FastCall(function, args, 2);
    }
    #endif
    #if CYTHON_FAST_PYCCALL
    if (__Pyx_PyFastCFunction_Check(function)) {
        PyObject *args[2] = {arg1, arg2};
        return __Pyx_PyCFunction_FastCall(function, args, 2);
    }
    #endif
    args = PyTuple_New(2);
    if (unlikely(!args)) goto done;
    Py_INCREF(arg1);
    PyTuple_SET_ITEM(args, 0, arg1);
    Py_INCREF(arg2);
    PyTuple_SET_ITEM(args, 1, arg2);
    Py_INCREF(function);
    result = __Pyx_PyObject_Call(function, args, NULL);
    Py_DECREF(args);
    Py_DECREF(function);
done:
    return result;
}

/* PyObjectCallMethO */
#if CYTHON_COMPILING_IN_CPYTHON
static CYTHON_INLINE PyObject* __Pyx_PyObject_CallMethO(PyObject *func, PyObject *arg) {
    PyObject *self, *result;
    PyCFunction cfunc;
    cfunc = PyCFunction_GET_FUNCTION(func);
    self = PyCFunction_GET_SELF(func);
    if (unlikely(Py_EnterRecursiveCall((char*)" while calling a Python object")))
        return NULL;
    result = cfunc(self, arg);
    Py_LeaveRecursiveCall();
    if (unlikely(!result) && unlikely(!PyErr_Occurred())) {
        PyErr_SetString(
            PyExc_SystemError,
            "NULL result without error in PyObject_Call");
    }
    return result;
}
#endif

/* PyObjectCallOneArg */
#if CYTHON_COMPILING_IN_CPYTHON
static PyObject* __Pyx__PyObject_CallOneArg(PyObject *func, PyObject *arg) {
    PyObject *result;
    PyObject *args = PyTuple_New(1);
    if (unlikely(!args)) return NULL;
    Py_INCREF(arg);
    PyTuple_SET_ITEM(args, 0, arg);
    result = __Pyx_PyObject_Call(func, args, NULL);
    Py_DECREF(args);
    return result;
}
static CYTHON_INLINE PyObject* __Pyx_PyObject_CallOneArg(PyObject *func, PyObject *arg) {
#if CYTHON_FAST_PYCALL
    if (PyFunction_Check(func)) {
        return __Pyx_PyFunction_FastCall(func, &arg, 1);
    }
#endif
    if (likely(PyCFunction_Check(func))) {
        if (likely(PyCFunction_GET_FLAGS(func) & METH_O)) {
            return __Pyx_PyObject_CallMethO(func, arg);
#if CYTHON_FAST_PYCCALL
        } else if (PyCFunction_GET_FLAGS(func) & METH_FASTCALL) {
            return __Pyx_PyCFunction_FastCall(func, &arg, 1);
#endif
        }
    }
    return __Pyx__PyObject_CallOneArg(func, arg);
}
#else
static CYTHON_INLINE PyObject* __Pyx_PyObject_CallOneArg(PyObject *func, PyObject *arg) {
    PyObject *result;
    PyObject *args = PyTuple_Pack(1, arg);
    if (unlikely(!args)) return NULL;
    result = __Pyx_PyObject_Call(func, args, NULL);
    Py_DECREF(args);
    return result;
}
#endif

/* ExtTypeTest */
static CYTHON_INLINE int __Pyx_TypeTest(PyObject *obj, PyTypeObject *type) {
    if (unlikely(!type)) {
        PyErr_SetString(PyExc_SystemError, "Missing type object");
        return 0;
    }
    if (likely(__Pyx_TypeCheck(obj, type)))
        return 1;
    PyErr_Format(PyExc_TypeError, "Cannot convert %.200s to %.200s",
                 Py_TYPE(obj)->tp_name, type->tp_name);
    return 0;
}

/* PyErrExceptionMatches */
#if CYTHON_FAST_THREAD_STATE
static int __Pyx_PyErr_ExceptionMatchesTuple(PyObject *exc_type, PyObject *tuple) {
    Py_ssize_t i, n;
    n = PyTuple_GET_SIZE(tuple);
#if PY_MAJOR_VERSION >= 3
    for (i=0; i<n; i++) {
        if (exc_type == PyTuple_GET_ITEM(tuple, i)) return 1;
    }
#endif
    for (i=0; i<n; i++) {
        if (__Pyx_PyErr_GivenExceptionMatches(exc_type, PyTuple_GET_ITEM(tuple, i))) return 1;
    }
    return 0;
}
static CYTHON_INLINE int __Pyx_PyErr_ExceptionMatchesInState(PyThreadState* tstate, PyObject* err) {
    PyObject *exc_type = tstate->curexc_type;
    if (exc_type == err) return 1;
    if (unlikely(!exc_type)) return 0;
    if (unlikely(PyTuple_Check(err)))
        return __Pyx_PyErr_ExceptionMatchesTuple(exc_type, err);
    return __Pyx_PyErr_GivenExceptionMatches(exc_type, err);
}
#endif

/* GetAttr */
static CYTHON_INLINE PyObject *__Pyx_GetAttr(PyObject *o, PyObject *n) {
#if CYTHON_USE_TYPE_SLOTS
#if PY_MAJOR_VERSION >= 3
    if (likely(PyUnicode_Check(n)))
#else
    if (likely(PyString_Check(n)))
#endif
        return __Pyx_PyObject_GetAttrStr(o, n);
#endif
    return PyObject_GetAttr(o, n);
}

/* GetAttr3 */
static PyObject *__Pyx_GetAttr3Default(PyObject *d) {
    __Pyx_PyThreadState_declare
    __Pyx_PyThreadState_assign
    if (unlikely(!__Pyx_PyErr_ExceptionMatches(PyExc_AttributeError)))
        return NULL;
    __Pyx_PyErr_Clear();
    Py_INCREF(d);
    return d;
}
static CYTHON_INLINE PyObject *__Pyx_GetAttr3(PyObject *o, PyObject *n, PyObject *d) {
    PyObject *r = __Pyx_GetAttr(o, n);
    return (likely(r)) ? r : __Pyx_GetAttr3Default(d);
}

/* PyDictVersioning */
#if CYTHON_USE_DICT_VERSIONS && CYTHON_USE_TYPE_SLOTS
static CYTHON_INLINE PY_UINT64_T __Pyx_get_tp_dict_version(PyObject *obj) {
    PyObject *dict = Py_TYPE(obj)->tp_dict;
    return likely(dict) ? __PYX_GET_DICT_VERSION(dict) : 0;
}
static CYTHON_INLINE PY_UINT64_T __Pyx_get_object_dict_version(PyObject *obj) {
    PyObject **dictptr = NULL;
    Py_ssize_t offset = Py_TYPE(obj)->tp_dictoffset;
    if (offset) {
#if CYTHON_COMPILING_IN_CPYTHON
        dictptr = (likely(offset > 0)) ? (PyObject **) ((char *)obj + offset) : _PyObject_GetDictPtr(obj);
#else
        dictptr = _PyObject_GetDictPtr(obj);
#endif
    }
    return (dictptr && *dictptr) ? __PYX_GET_DICT_VERSION(*dictptr) : 0;
}
static CYTHON_INLINE int __Pyx_object_dict_version_matches(PyObject* obj, PY_UINT64_T tp_dict_version, PY_UINT64_T obj_dict_version) {
    PyObject *dict = Py_TYPE(obj)->tp_dict;
    if (unlikely(!dict) || unlikely(tp_dict_version != __PYX_GET_DICT_VERSION(dict)))
        return 0;
    return obj_dict_version == __Pyx_get_object_dict_version(obj);
}
#endif

/* GetModuleGlobalName */
#if CYTHON_USE_DICT_VERSIONS
static PyObject *__Pyx__GetModuleGlobalName(PyObject *name, PY_UINT64_T *dict_version, PyObject **dict_cached_value)
#else
static CYTHON_INLINE PyObject *__Pyx__GetModuleGlobalName(PyObject *name)
#endif
{
    PyObject *result;
#if !CYTHON_AVOID_BORROWED_REFS
#if CYTHON_COMPILING_IN_CPYTHON && PY_VERSION_HEX >= 0x030500A1
    result = _PyDict_GetItem_KnownHash(__pyx_d, name, ((PyASCIIObject *) name)->hash);
    __PYX_UPDATE_DICT_CACHE(__pyx_d, result, *dict_cached_value, *dict_version)
    if (likely(result)) {
        return __Pyx_NewRef(result);
    } else if (unlikely(PyErr_Occurred())) {
        return NULL;
    }
#else
    result = PyDict_GetItem(__pyx_d, name);
    __PYX_UPDATE_DICT_CACHE(__pyx_d, result, *dict_cached_value, *dict_version)
    if (likely(result)) {
        return __Pyx_NewRef(result);
    }
#endif
#else
    result = PyObject_GetItem(__pyx_d, name);
    __PYX_UPDATE_DICT_CACHE(__pyx_d, result, *dict_cached_value, *dict_version)
    if (likely(result)) {
        return __Pyx_NewRef(result);
    }
    PyErr_Clear();
#endif
    return __Pyx_GetBuiltinName(name);
}

/* GetItemInt */
static PyObject *__Pyx_GetItemInt_Generic(PyObject *o, PyObject* j) {
    PyObject *r;
    if (!j) return NULL;
    r = PyObject_GetItem(o, j);
    Py_DECREF(j);
    return r;
}
static CYTHON_INLINE PyObject *__Pyx_GetItemInt_List_Fast(PyObject *o, Py_ssize_t i,
                                                              CYTHON_NCP_UNUSED int wraparound,
                                                              CYTHON_NCP_UNUSED int boundscheck) {
#if CYTHON_ASSUME_SAFE_MACROS && !CYTHON_AVOID_BORROWED_REFS
    Py_ssize_t wrapped_i = i;
    if (wraparound & unlikely(i < 0)) {
        wrapped_i += PyList_GET_SIZE(o);
    }
    if ((!boundscheck) || likely(__Pyx_is_valid_index(wrapped_i, PyList_GET_SIZE(o)))) {
        PyObject *r = PyList_GET_ITEM(o, wrapped_i);
        Py_INCREF(r);
        return r;
    }
    return __Pyx_GetItemInt_Generic(o, PyInt_FromSsize_t(i));
#else
    return PySequence_GetItem(o, i);
#endif
}
static CYTHON_INLINE PyObject *__Pyx_GetItemInt_Tuple_Fast(PyObject *o, Py_ssize_t i,
                                                              CYTHON_NCP_UNUSED int wraparound,
                                                              CYTHON_NCP_UNUSED int boundscheck) {
#if CYTHON_ASSUME_SAFE_MACROS && !CYTHON_AVOID_BORROWED_REFS
    Py_ssize_t wrapped_i = i;
    if (wraparound & unlikely(i < 0)) {
        wrapped_i += PyTuple_GET_SIZE(o);
    }
    if ((!boundscheck) || likely(__Pyx_is_valid_index(wrapped_i, PyTuple_GET_SIZE(o)))) {
        PyObject *r = PyTuple_GET_ITEM(o, wrapped_i);
        Py_INCREF(r);
        return r;
    }
    return __Pyx_GetItemInt_Generic(o, PyInt_FromSsize_t(i));
#else
    return PySequence_GetItem(o, i);
#endif
}
static CYTHON_INLINE PyObject *__Pyx_GetItemInt_Fast(PyObject *o, Py_ssize_t i, int is_list,
                                                     CYTHON_NCP_UNUSED int wraparound,
                                                     CYTHON_NCP_UNUSED int boundscheck) {
#if CYTHON_ASSUME_SAFE_MACROS && !CYTHON_AVOID_BORROWED_REFS && CYTHON_USE_TYPE_SLOTS
    if (is_list || PyList_CheckExact(o)) {
        Py_ssize_t n = ((!wraparound) | likely(i >= 0)) ? i : i + PyList_GET_SIZE(o);
        if ((!boundscheck) || (likely(__Pyx_is_valid_index(n, PyList_GET_SIZE(o))))) {
            PyObject *r = PyList_GET_ITEM(o, n);
            Py_INCREF(r);
            return r;
        }
    }
    else if (PyTuple_CheckExact(o)) {
        Py_ssize_t n = ((!wraparound) | likely(i >= 0)) ? i : i + PyTuple_GET_SIZE(o);
        if ((!boundscheck) || likely(__Pyx_is_valid_index(n, PyTuple_GET_SIZE(o)))) {
            PyObject *r = PyTuple_GET_ITEM(o, n);
            Py_INCREF(r);
            return r;
        }
    } else {
        PySequenceMethods *m = Py_TYPE(o)->tp_as_sequence;
        if (likely(m && m->sq_item)) {
            if (wraparound && unlikely(i < 0) && likely(m->sq_length)) {
                Py_ssize_t l = m->sq_length(o);
                if (likely(l >= 0)) {
                    i += l;
                } else {
                    if (!PyErr_ExceptionMatches(PyExc_OverflowError))
                        return NULL;
                    PyErr_Clear();
                }
            }
            return m->sq_item(o, i);
        }
    }
#else
    if (is_list || PySequence_Check(o)) {
        return PySequence_GetItem(o, i);
    }
#endif
    return __Pyx_GetItemInt_Generic(o, PyInt_FromSsize_t(i));
}

/* ObjectGetItem */
#if CYTHON_USE_TYPE_SLOTS
static PyObject *__Pyx_PyObject_GetIndex(PyObject *obj, PyObject* index) {
    PyObject *runerr;
    Py_ssize_t key_value;
    PySequenceMethods *m = Py_TYPE(obj)->tp_as_sequence;
    if (unlikely(!(m && m->sq_item))) {
        PyErr_Format(PyExc_TypeError, "'%.200s' object is not subscriptable", Py_TYPE(obj)->tp_name);
        return NULL;
    }
    key_value = __Pyx_PyIndex_AsSsize_t(index);
    if (likely(key_value != -1 || !(runerr = PyErr_Occurred()))) {
        return __Pyx_GetItemInt_Fast(obj, key_value, 0, 1, 1);
    }
    if (PyErr_GivenExceptionMatches(runerr, PyExc_OverflowError)) {
        PyErr_Clear();
        PyErr_Format(PyExc_IndexError, "cannot fit '%.200s' into an index-sized integer", Py_TYPE(index)->tp_name);
    }
    return NULL;
}
static PyObject *__Pyx_PyObject_GetItem(PyObject *obj, PyObject* key) {
    PyMappingMethods *m = Py_TYPE(obj)->tp_as_mapping;
    if (likely(m && m->mp_subscript)) {
        return m->mp_subscript(obj, key);
    }
    return __Pyx_PyObject_GetIndex(obj, key);
}
#endif

/* BytesEquals */
static CYTHON_INLINE int __Pyx_PyBytes_Equals(PyObject* s1, PyObject* s2, int equals) {
#if CYTHON_COMPILING_IN_PYPY
    return PyObject_RichCompareBool(s1, s2, equals);
#else
    if (s1 == s2) {
        return (equals == Py_EQ);
    } else if (PyBytes_CheckExact(s1) & PyBytes_CheckExact(s2)) {
        const char *ps1, *ps2;
        Py_ssize_t length = PyBytes_GET_SIZE(s1);
        if (length != PyBytes_GET_SIZE(s2))
            return (equals == Py_NE);
        ps1 = PyBytes_AS_STRING(s1);
        ps2 = PyBytes_AS_STRING(s2);
        if (ps1[0] != ps2[0]) {
            return (equals == Py_NE);
        } else if (length == 1) {
            return (equals == Py_EQ);
        } else {
            int result;
#if CYTHON_USE_UNICODE_INTERNALS
            Py_hash_t hash1, hash2;
            hash1 = ((PyBytesObject*)s1)->ob_shash;
            hash2 = ((PyBytesObject*)s2)->ob_shash;
            if (hash1 != hash2 && hash1 != -1 && hash2 != -1) {
                return (equals == Py_NE);
            }
#endif
            result = memcmp(ps1, ps2, (size_t)length);
            return (equals == Py_EQ) ? (result == 0) : (result != 0);
        }
    } else if ((s1 == Py_None) & PyBytes_CheckExact(s2)) {
        return (equals == Py_NE);
    } else if ((s2 == Py_None) & PyBytes_CheckExact(s1)) {
        return (equals == Py_NE);
    } else {
        int result;
        PyObject* py_result = PyObject_RichCompare(s1, s2, equals);
        if (!py_result)
            return -1;
        result = __Pyx_PyObject_IsTrue(py_result);
        Py_DECREF(py_result);
        return result;
    }
#endif
}

/* UnicodeEquals */
static CYTHON_INLINE int __Pyx_PyUnicode_Equals(PyObject* s1, PyObject* s2, int equals) {
#if CYTHON_COMPILING_IN_PYPY
    return PyObject_RichCompareBool(s1, s2, equals);
#else
#if PY_MAJOR_VERSION < 3
    PyObject* owned_ref = NULL;
#endif
    int s1_is_unicode, s2_is_unicode;
    if (s1 == s2) {
        goto return_eq;
    }
    s1_is_unicode = PyUnicode_CheckExact(s1);
    s2_is_unicode = PyUnicode_CheckExact(s2);
#if PY_MAJOR_VERSION < 3
    if ((s1_is_unicode & (!s2_is_unicode)) && PyString_CheckExact(s2)) {
        owned_ref = PyUnicode_FromObject(s2);
        if (unlikely(!owned_ref))
            return -1;
        s2 = owned_ref;
        s2_is_unicode = 1;
    } else if ((s2_is_unicode & (!s1_is_unicode)) && PyString_CheckExact(s1)) {
        owned_ref = PyUnicode_FromObject(s1);
        if (unlikely(!owned_ref))
            return -1;
        s1 = owned_ref;
        s1_is_unicode = 1;
    } else if (((!s2_is_unicode) & (!s1_is_unicode))) {
        return __Pyx_PyBytes_Equals(s1, s2, equals);
    }
#endif
    if (s1_is_unicode & s2_is_unicode) {
        Py_ssize_t length;
        int kind;
        void *data1, *data2;
        if (unlikely(__Pyx_PyUnicode_READY(s1) < 0) || unlikely(__Pyx_PyUnicode_READY(s2) < 0))
            return -1;
        length = __Pyx_PyUnicode_GET_LENGTH(s1);
        if (length != __Pyx_PyUnicode_GET_LENGTH(s2)) {
            goto return_ne;
        }
#if CYTHON_USE_UNICODE_INTERNALS
        {
            Py_hash_t hash1, hash2;
        #if CYTHON_PEP393_ENABLED
            hash1 = ((PyASCIIObject*)s1)->hash;
            hash2 = ((PyASCIIObject*)s2)->hash;
        #else
            hash1 = ((PyUnicodeObject*)s1)->hash;
            hash2 = ((PyUnicodeObject*)s2)->hash;
        #endif
            if (hash1 != hash2 && hash1 != -1 && hash2 != -1) {
                goto return_ne;
            }
        }
#endif
        kind = __Pyx_PyUnicode_KIND(s1);
        if (kind != __Pyx_PyUnicode_KIND(s2)) {
            goto return_ne;
        }
        data1 = __Pyx_PyUnicode_DATA(s1);
        data2 = __Pyx_PyUnicode_DATA(s2);
        if (__Pyx_PyUnicode_READ(kind, data1, 0) != __Pyx_PyUnicode_READ(kind, data2, 0)) {
            goto return_ne;
        } else if (length == 1) {
            goto return_eq;
        } else {
            int result = memcmp(data1, data2, (size_t)(length * kind));
            #if PY_MAJOR_VERSION < 3
            Py_XDECREF(owned_ref);
            #endif
            return (equals == Py_EQ) ? (result == 0) : (result != 0);
        }
    } else if ((s1 == Py_None) & s2_is_unicode) {
        goto return_ne;
    } else if ((s2 == Py_None) & s1_is_unicode) {
        goto return_ne;
    } else {
        int result;
        PyObject* py_result = PyObject_RichCompare(s1, s2, equals);
        #if PY_MAJOR_VERSION < 3
        Py_XDECREF(owned_ref);
        #endif
        if (!py_result)
            return -1;
        result = __Pyx_PyObject_IsTrue(py_result);
        Py_DECREF(py_result);
        return result;
    }
return_eq:
    #if PY_MAJOR_VERSION < 3
    Py_XDECREF(owned_ref);
    #endif
    return (equals == Py_EQ);
return_ne:
    #if PY_MAJOR_VERSION < 3
    Py_XDECREF(owned_ref);
    #endif
    return (equals == Py_NE);
#endif
}

/* RaiseException */
#if PY_MAJOR_VERSION < 3
static void __Pyx_Raise(PyObject *type, PyObject *value, PyObject *tb,
                        CYTHON_UNUSED PyObject *cause) {
    __Pyx_PyThreadState_declare
    Py_XINCREF(type);
    if (!value || value == Py_None)
        value = NULL;
    else
        Py_INCREF(value);
    if (!tb || tb == Py_None)
        tb = NULL;
    else {
        Py_INCREF(tb);
        if (!PyTraceBack_Check(tb)) {
            PyErr_SetString(PyExc_TypeError,
                "raise: arg 3 must be a traceback or None");
            goto raise_error;
        }
    }
    if (PyType_Check(type)) {
#if CYTHON_COMPILING_IN_PYPY
        if (!value) {
            Py_INCREF(Py_None);
            value = Py_None;
        }
#endif
        PyErr_NormalizeException(&type, &value, &tb);
    } else {
        if (value) {
            PyErr_SetString(PyExc_TypeError,
                "instance exception may not have a separate value");
            goto raise_error;
        }
        value = type;
        type = (PyObject*) Py_TYPE(type);
        Py_INCREF(type);
        if (!PyType_IsSubtype((PyTypeObject *)type, (PyTypeObject *)PyExc_BaseException)) {
            PyErr_SetString(PyExc_TypeError,
                "raise: exception class must be a subclass of BaseException");
            goto raise_error;
        }
    }
    __Pyx_PyThreadState_assign
    __Pyx_ErrRestore(type, value, tb);
    return;
raise_error:
    Py_XDECREF(value);
    Py_XDECREF(type);
    Py_XDECREF(tb);
    return;
}
#else
static void __Pyx_Raise(PyObject *type, PyObject *value, PyObject *tb, PyObject *cause) {
    PyObject* owned_instance = NULL;
    if (tb == Py_None) {
        tb = 0;
    } else if (tb && !PyTraceBack_Check(tb)) {
        PyErr_SetString(PyExc_TypeError,
            "raise: arg 3 must be a traceback or None");
        goto bad;
    }
    if (value == Py_None)
        value = 0;
    if (PyExceptionInstance_Check(type)) {
        if (value) {
            PyErr_SetString(PyExc_TypeError,
                "instance exception may not have a separate value");
            goto bad;
        }
        value = type;
        type = (PyObject*) Py_TYPE(value);
    } else if (PyExceptionClass_Check(type)) {
        PyObject *instance_class = NULL;
        if (value && PyExceptionInstance_Check(value)) {
            instance_class = (PyObject*) Py_TYPE(value);
            if (instance_class != type) {
                int is_subclass = PyObject_IsSubclass(instance_class, type);
                if (!is_subclass) {
                    instance_class = NULL;
                } else if (unlikely(is_subclass == -1)) {
                    goto bad;
                } else {
                    type = instance_class;
                }
            }
        }
        if (!instance_class) {
            PyObject *args;
            if (!value)
                args = PyTuple_New(0);
            else if (PyTuple_Check(value)) {
                Py_INCREF(value);
                args = value;
            } else
                args = PyTuple_Pack(1, value);
            if (!args)
                goto bad;
            owned_instance = PyObject_Call(type, args, NULL);
            Py_DECREF(args);
            if (!owned_instance)
                goto bad;
            value = owned_instance;
            if (!PyExceptionInstance_Check(value)) {
                PyErr_Format(PyExc_TypeError,
                             "calling %R should have returned an instance of "
                             "BaseException, not %R",
                             type, Py_TYPE(value));
                goto bad;
            }
        }
    } else {
        PyErr_SetString(PyExc_TypeError,
            "raise: exception class must be a subclass of BaseException");
        goto bad;
    }
    if (cause) {
        PyObject *fixed_cause;
        if (cause == Py_None) {
            fixed_cause = NULL;
        } else if (PyExceptionClass_Check(cause)) {
            fixed_cause = PyObject_CallObject(cause, NULL);
            if (fixed_cause == NULL)
                goto bad;
        } else if (PyExceptionInstance_Check(cause)) {
            fixed_cause = cause;
            Py_INCREF(fixed_cause);
        } else {
            PyErr_SetString(PyExc_TypeError,
                            "exception causes must derive from "
                            "BaseException");
            goto bad;
        }
        PyException_SetCause(value, fixed_cause);
    }
    PyErr_SetObject(type, value);
    if (tb) {
#if CYTHON_COMPILING_IN_PYPY
        PyObject *tmp_type, *tmp_value, *tmp_tb;
        PyErr_Fetch(&tmp_type, &tmp_value, &tmp_tb);
        Py_INCREF(tb);
        PyErr_Restore(tmp_type, tmp_value, tb);
        Py_XDECREF(tmp_tb);
#else
        PyThreadState *tstate = __Pyx_PyThreadState_Current;
        PyObject* tmp_tb = tstate->curexc_traceback;
        if (tb != tmp_tb) {
            Py_INCREF(tb);
            tstate->curexc_traceback = tb;
            Py_XDECREF(tmp_tb);
        }
#endif
    }
bad:
    Py_XDECREF(owned_instance);
    return;
}
#endif

/* Import */
static PyObject *__Pyx_Import(PyObject *name, PyObject *from_list, int level) {
    PyObject *empty_list = 0;
    PyObject *module = 0;
    PyObject *global_dict = 0;
    PyObject *empty_dict = 0;
    PyObject *list;
    #if PY_MAJOR_VERSION < 3
    PyObject *py_import;
    py_import = __Pyx_PyObject_GetAttrStr(__pyx_b, __pyx_n_s_import);
    if (!py_import)
        goto bad;
    #endif
    if (from_list)
        list = from_list;
    else {
        empty_list = PyList_New(0);
        if (!empty_list)
            goto bad;
        list = empty_list;
    }
    global_dict = PyModule_GetDict(__pyx_m);
    if (!global_dict)
        goto bad;
    empty_dict = PyDict_New();
    if (!empty_dict)
        goto bad;
    {
        #if PY_MAJOR_VERSION >= 3
        if (level == -1) {
            if ((1) && (strchr(__Pyx_MODULE_NAME, '.'))) {
                module = PyImport_ImportModuleLevelObject(
                    name, global_dict, empty_dict, list, 1);
                if (!module) {
                    if (!PyErr_ExceptionMatches(PyExc_ImportError))
                        goto bad;
                    PyErr_Clear();
                }
            }
            level = 0;
        }
        #endif
        if (!module) {
            #if PY_MAJOR_VERSION < 3
            PyObject *py_level = PyInt_FromLong(level);
            if (!py_level)
                goto bad;
            module = PyObject_CallFunctionObjArgs(py_import,
                name, global_dict, empty_dict, list, py_level, (PyObject *)NULL);
            Py_DECREF(py_level);
            #else
            module = PyImport_ImportModuleLevelObject(
                name, global_dict, empty_dict, list, level);
            #endif
        }
    }
bad:
    #if PY_MAJOR_VERSION < 3
    Py_XDECREF(py_import);
    #endif
    Py_XDECREF(empty_list);
    Py_XDECREF(empty_dict);
    return module;
}

/* ImportFrom */
static PyObject* __Pyx_ImportFrom(PyObject* module, PyObject* name) {
    PyObject* value = __Pyx_PyObject_GetAttrStr(module, name);
    if (unlikely(!value) && PyErr_ExceptionMatches(PyExc_AttributeError)) {
        PyErr_Format(PyExc_ImportError,
        #if PY_MAJOR_VERSION < 3
            "cannot import name %.230s", PyString_AS_STRING(name));
        #else
            "cannot import name %S", name);
        #endif
    }
    return value;
}

/* HasAttr */
static CYTHON_INLINE int __Pyx_HasAttr(PyObject *o, PyObject *n) {
    PyObject *r;
    if (unlikely(!__Pyx_PyBaseString_Check(n))) {
        PyErr_SetString(PyExc_TypeError,
                        "hasattr(): attribute name must be string");
        return -1;
    }
    r = __Pyx_GetAttr(o, n);
    if (unlikely(!r)) {
        PyErr_Clear();
        return 0;
    } else {
        Py_DECREF(r);
        return 1;
    }
}

/* GetTopmostException */
#if CYTHON_USE_EXC_INFO_STACK
static _PyErr_StackItem *
__Pyx_PyErr_GetTopmostException(PyThreadState *tstate)
{
    _PyErr_StackItem *exc_info = tstate->exc_info;
    while ((exc_info->exc_type == NULL || exc_info->exc_type == Py_None) &&
           exc_info->previous_item != NULL)
    {
        exc_info = exc_info->previous_item;
    }
    return exc_info;
}
#endif

/* SaveResetException */
#if CYTHON_FAST_THREAD_STATE
static CYTHON_INLINE void __Pyx__ExceptionSave(PyThreadState *tstate, PyObject **type, PyObject **value, PyObject **tb) {
    #if CYTHON_USE_EXC_INFO_STACK
    _PyErr_StackItem *exc_info = __Pyx_PyErr_GetTopmostException(tstate);
    *type = exc_info->exc_type;
    *value = exc_info->exc_value;
    *tb = exc_info->exc_traceback;
    #else
    *type = tstate->exc_type;
    *value = tstate->exc_value;
    *tb = tstate->exc_traceback;
    #endif
    Py_XINCREF(*type);
    Py_XINCREF(*value);
    Py_XINCREF(*tb);
}
static CYTHON_INLINE void __Pyx__ExceptionReset(PyThreadState *tstate, PyObject *type, PyObject *value, PyObject *tb) {
    PyObject *tmp_type, *tmp_value, *tmp_tb;
    #if CYTHON_USE_EXC_INFO_STACK
    _PyErr_StackItem *exc_info = tstate->exc_info;
    tmp_type = exc_info->exc_type;
    tmp_value = exc_info->exc_value;
    tmp_tb = exc_info->exc_traceback;
    exc_info->exc_type = type;
    exc_info->exc_value = value;
    exc_info->exc_traceback = tb;
    #else
    tmp_type = tstate->exc_type;
    tmp_value = tstate->exc_value;
    tmp_tb = tstate->exc_traceback;
    tstate->exc_type = type;
    tstate->exc_value = value;
    tstate->exc_traceback = tb;
    #endif
    Py_XDECREF(tmp_type);
    Py_XDECREF(tmp_value);
    Py_XDECREF(tmp_tb);
}
#endif

/* GetException */
#if CYTHON_FAST_THREAD_STATE
static int __Pyx__GetException(PyThreadState *tstate, PyObject **type, PyObject **value, PyObject **tb)
#else
static int __Pyx_GetException(PyObject **type, PyObject **value, PyObject **tb)
#endif
{
    PyObject *local_type, *local_value, *local_tb;
#if CYTHON_FAST_THREAD_STATE
    PyObject *tmp_type, *tmp_value, *tmp_tb;
    local_type = tstate->curexc_type;
    local_value = tstate->curexc_value;
    local_tb = tstate->curexc_traceback;
    tstate->curexc_type = 0;
    tstate->curexc_value = 0;
    tstate->curexc_traceback = 0;
#else
    PyErr_Fetch(&local_type, &local_value, &local_tb);
#endif
    PyErr_NormalizeException(&local_type, &local_value, &local_tb);
#if CYTHON_FAST_THREAD_STATE
    if (unlikely(tstate->curexc_type))
#else
    if (unlikely(PyErr_Occurred()))
#endif
        goto bad;
    #if PY_MAJOR_VERSION >= 3
    if (local_tb) {
        if (unlikely(PyException_SetTraceback(local_value, local_tb) < 0))
            goto bad;
    }
    #endif
    Py_XINCREF(local_tb);
    Py_XINCREF(local_type);
    Py_XINCREF(local_value);
    *type = local_type;
    *value = local_value;
    *tb = local_tb;
#if CYTHON_FAST_THREAD_STATE
    #if CYTHON_USE_EXC_INFO_STACK
    {
        _PyErr_StackItem *exc_info = tstate->exc_info;
        tmp_type = exc_info->exc_type;
        tmp_value = exc_info->exc_value;
        tmp_tb = exc_info->exc_traceback;
        exc_info->exc_type = local_type;
        exc_info->exc_value = local_value;
        exc_info->exc_traceback = local_tb;
    }
    #else
    tmp_type = tstate->exc_type;
    tmp_value = tstate->exc_value;
    tmp_tb = tstate->exc_traceback;
    tstate->exc_type = local_type;
    tstate->exc_value = local_value;
    tstate->exc_traceback = local_tb;
    #endif
    Py_XDECREF(tmp_type);
    Py_XDECREF(tmp_value);
    Py_XDECREF(tmp_tb);
#else
    PyErr_SetExcInfo(local_type, local_value, local_tb);
#endif
    return 0;
bad:
    *type = 0;
    *value = 0;
    *tb = 0;
    Py_XDECREF(local_type);
    Py_XDECREF(local_value);
    Py_XDECREF(local_tb);
    return -1;
}

/* CallNextTpDealloc */
static void __Pyx_call_next_tp_dealloc(PyObject* obj, destructor current_tp_dealloc) {
    PyTypeObject* type = Py_TYPE(obj);
    while (type && type->tp_dealloc != current_tp_dealloc)
        type = type->tp_base;
    while (type && type->tp_dealloc == current_tp_dealloc)
        type = type->tp_base;
    if (type)
        type->tp_dealloc(obj);
}

/* CallNextTpTraverse */
static int __Pyx_call_next_tp_traverse(PyObject* obj, visitproc v, void *a, traverseproc current_tp_traverse) {
    PyTypeObject* type = Py_TYPE(obj);
    while (type && type->tp_traverse != current_tp_traverse)
        type = type->tp_base;
    while (type && type->tp_traverse == current_tp_traverse)
        type = type->tp_base;
    if (type && type->tp_traverse)
        return type->tp_traverse(obj, v, a);
    return 0;
}

/* CallNextTpClear */
static void __Pyx_call_next_tp_clear(PyObject* obj, inquiry current_tp_clear) {
    PyTypeObject* type = Py_TYPE(obj);
    while (type && type->tp_clear != current_tp_clear)
        type = type->tp_base;
    while (type && type->tp_clear == current_tp_clear)
        type = type->tp_base;
    if (type && type->tp_clear)
        type->tp_clear(obj);
}

/* TypeImport */
#ifndef __PYX_HAVE_RT_ImportType
#define __PYX_HAVE_RT_ImportType
static PyTypeObject *__Pyx_ImportType(PyObject *module, const char *module_name, const char *class_name,
    size_t size, enum __Pyx_ImportType_CheckSize check_size)
{
    PyObject *result = 0;
    char warning[200];
    Py_ssize_t basicsize;
#ifdef Py_LIMITED_API
    PyObject *py_basicsize;
#endif
    result = PyObject_GetAttrString(module, class_name);
    if (!result)
        goto bad;
    if (!PyType_Check(result)) {
        PyErr_Format(PyExc_TypeError,
            "%.200s.%.200s is not a type object",
            module_name, class_name);
        goto bad;
    }
#ifndef Py_LIMITED_API
    basicsize = ((PyTypeObject *)result)->tp_basicsize;
#else
    py_basicsize = PyObject_GetAttrString(result, "__basicsize__");
    if (!py_basicsize)
        goto bad;
    basicsize = PyLong_AsSsize_t(py_basicsize);
    Py_DECREF(py_basicsize);
    py_basicsize = 0;
    if (basicsize == (Py_ssize_t)-1 && PyErr_Occurred())
        goto bad;
#endif
    if ((size_t)basicsize < size) {
        PyErr_Format(PyExc_ValueError,
            "%.200s.%.200s size changed, may indicate binary incompatibility. "
            "Expected %zd from C header, got %zd from PyObject",
            module_name, class_name, size, basicsize);
        goto bad;
    }
    if (check_size == __Pyx_ImportType_CheckSize_Error && (size_t)basicsize != size) {
        PyErr_Format(PyExc_ValueError,
            "%.200s.%.200s size changed, may indicate binary incompatibility. "
            "Expected %zd from C header, got %zd from PyObject",
            module_name, class_name, size, basicsize);
        goto bad;
    }
    else if (check_size == __Pyx_ImportType_CheckSize_Warn && (size_t)basicsize > size) {
        PyOS_snprintf(warning, sizeof(warning),
            "%s.%s size changed, may indicate binary incompatibility. "
            "Expected %zd from C header, got %zd from PyObject",
            module_name, class_name, size, basicsize);
        if (PyErr_WarnEx(NULL, warning, 0) < 0) goto bad;
    }
    return (PyTypeObject *)result;
bad:
    Py_XDECREF(result);
    return NULL;
}
#endif

/* GetVTable */
static void* __Pyx_GetVtable(PyObject *dict) {
    void* ptr;
    PyObject *ob = PyObject_GetItem(dict, __pyx_n_s_pyx_vtable);
    if (!ob)
        goto bad;
#if PY_VERSION_HEX >= 0x02070000
    ptr = PyCapsule_GetPointer(ob, 0);
#else
    ptr = PyCObject_AsVoidPtr(ob);
#endif
    if (!ptr && !PyErr_Occurred())
        PyErr_SetString(PyExc_RuntimeError, "invalid vtable found for imported type");
    Py_DECREF(ob);
    return ptr;
bad:
    Py_XDECREF(ob);
    return NULL;
}

/* PyObject_GenericGetAttrNoDict */
#if CYTHON_USE_TYPE_SLOTS && CYTHON_USE_PYTYPE_LOOKUP && PY_VERSION_HEX < 0x03070000
static PyObject *__Pyx_RaiseGenericGetAttributeError(PyTypeObject *tp, PyObject *attr_name) {
    PyErr_Format(PyExc_AttributeError,
#if PY_MAJOR_VERSION >= 3
                 "'%.50s' object has no attribute '%U'",
                 tp->tp_name, attr_name);
#else
                 "'%.50s' object has no attribute '%.400s'",
                 tp->tp_name, PyString_AS_STRING(attr_name));
#endif
    return NULL;
}
static CYTHON_INLINE PyObject* __Pyx_PyObject_GenericGetAttrNoDict(PyObject* obj, PyObject* attr_name) {
    PyObject *descr;
    PyTypeObject *tp = Py_TYPE(obj);
    if (unlikely(!PyString_Check(attr_name))) {
        return PyObject_GenericGetAttr(obj, attr_name);
    }
    assert(!tp->tp_dictoffset);
    descr = _PyType_Lookup(tp, attr_name);
    if (unlikely(!descr)) {
        return __Pyx_RaiseGenericGetAttributeError(tp, attr_name);
    }
    Py_INCREF(descr);
    #if PY_MAJOR_VERSION < 3
    if (likely(PyType_HasFeature(Py_TYPE(descr), Py_TPFLAGS_HAVE_CLASS)))
    #endif
    {
        descrgetfunc f = Py_TYPE(descr)->tp_descr_get;
        if (unlikely(f)) {
            PyObject *res = f(descr, obj, (PyObject *)tp);
            Py_DECREF(descr);
            return res;
        }
    }
    return descr;
}
#endif

/* SetVTable */
static int __Pyx_SetVtable(PyObject *dict, void *vtable) {
#if PY_VERSION_HEX >= 0x02070000
    PyObject *ob = PyCapsule_New(vtable, 0, 0);
#else
    PyObject *ob = PyCObject_FromVoidPtr(vtable, 0);
#endif
    if (!ob)
        goto bad;
    if (PyDict_SetItem(dict, __pyx_n_s_pyx_vtable, ob) < 0)
        goto bad;
    Py_DECREF(ob);
    return 0;
bad:
    Py_XDECREF(ob);
    return -1;
}

/* PyObjectGetAttrStrNoError */
static void __Pyx_PyObject_GetAttrStr_ClearAttributeError(void) {
    __Pyx_PyThreadState_declare
    __Pyx_PyThreadState_assign
    if (likely(__Pyx_PyErr_ExceptionMatches(PyExc_AttributeError)))
        __Pyx_PyErr_Clear();
}
static CYTHON_INLINE PyObject* __Pyx_PyObject_GetAttrStrNoError(PyObject* obj, PyObject* attr_name) {
    PyObject *result;
#if CYTHON_COMPILING_IN_CPYTHON && CYTHON_USE_TYPE_SLOTS && PY_VERSION_HEX >= 0x030700B1
    PyTypeObject* tp = Py_TYPE(obj);
    if (likely(tp->tp_getattro == PyObject_GenericGetAttr)) {
        return _PyObject_GenericGetAttrWithDict(obj, attr_name, NULL, 1);
    }
#endif
    result = __Pyx_PyObject_GetAttrStr(obj, attr_name);
    if (unlikely(!result)) {
        __Pyx_PyObject_GetAttrStr_ClearAttributeError();
    }
    return result;
}

/* SetupReduce */
static int __Pyx_setup_reduce_is_named(PyObject* meth, PyObject* name) {
  int ret;
  PyObject *name_attr;
  name_attr = __Pyx_PyObject_GetAttrStr(meth, __pyx_n_s_name);
  if (likely(name_attr)) {
      ret = PyObject_RichCompareBool(name_attr, name, Py_EQ);
  } else {
      ret = -1;
  }
  if (unlikely(ret < 0)) {
      PyErr_Clear();
      ret = 0;
  }
  Py_XDECREF(name_attr);
  return ret;
}
static int __Pyx_setup_reduce(PyObject* type_obj) {
    int ret = 0;
    PyObject *object_reduce = NULL;
    PyObject *object_reduce_ex = NULL;
    PyObject *reduce = NULL;
    PyObject *reduce_ex = NULL;
    PyObject *reduce_cython = NULL;
    PyObject *setstate = NULL;
    PyObject *setstate_cython = NULL;
#if CYTHON_USE_PYTYPE_LOOKUP
    if (_PyType_Lookup((PyTypeObject*)type_obj, __pyx_n_s_getstate)) goto __PYX_GOOD;
#else
    if (PyObject_HasAttr(type_obj, __pyx_n_s_getstate)) goto __PYX_GOOD;
#endif
#if CYTHON_USE_PYTYPE_LOOKUP
    object_reduce_ex = _PyType_Lookup(&PyBaseObject_Type, __pyx_n_s_reduce_ex); if (!object_reduce_ex) goto __PYX_BAD;
#else
    object_reduce_ex = __Pyx_PyObject_GetAttrStr((PyObject*)&PyBaseObject_Type, __pyx_n_s_reduce_ex); if (!object_reduce_ex) goto __PYX_BAD;
#endif
    reduce_ex = __Pyx_PyObject_GetAttrStr(type_obj, __pyx_n_s_reduce_ex); if (unlikely(!reduce_ex)) goto __PYX_BAD;
    if (reduce_ex == object_reduce_ex) {
#if CYTHON_USE_PYTYPE_LOOKUP
        object_reduce = _PyType_Lookup(&PyBaseObject_Type, __pyx_n_s_reduce); if (!object_reduce) goto __PYX_BAD;
#else
        object_reduce = __Pyx_PyObject_GetAttrStr((PyObject*)&PyBaseObject_Type, __pyx_n_s_reduce); if (!object_reduce) goto __PYX_BAD;
#endif
        reduce = __Pyx_PyObject_GetAttrStr(type_obj, __pyx_n_s_reduce); if (unlikely(!reduce)) goto __PYX_BAD;
        if (reduce == object_reduce || __Pyx_setup_reduce_is_named(reduce, __pyx_n_s_reduce_cython)) {
            reduce_cython = __Pyx_PyObject_GetAttrStrNoError(type_obj, __pyx_n_s_reduce_cython);
            if (likely(reduce_cython)) {
                ret = PyDict_SetItem(((PyTypeObject*)type_obj)->tp_dict, __pyx_n_s_reduce, reduce_cython); if (unlikely(ret < 0)) goto __PYX_BAD;
                ret = PyDict_DelItem(((PyTypeObject*)type_obj)->tp_dict, __pyx_n_s_reduce_cython); if (unlikely(ret < 0)) goto __PYX_BAD;
            } else if (reduce == object_reduce || PyErr_Occurred()) {
                goto __PYX_BAD;
            }
            setstate = __Pyx_PyObject_GetAttrStr(type_obj, __pyx_n_s_setstate);
            if (!setstate) PyErr_Clear();
            if (!setstate || __Pyx_setup_reduce_is_named(setstate, __pyx_n_s_setstate_cython)) {
                setstate_cython = __Pyx_PyObject_GetAttrStrNoError(type_obj, __pyx_n_s_setstate_cython);
                if (likely(setstate_cython)) {
                    ret = PyDict_SetItem(((PyTypeObject*)type_obj)->tp_dict, __pyx_n_s_setstate, setstate_cython); if (unlikely(ret < 0)) goto __PYX_BAD;
                    ret = PyDict_DelItem(((PyTypeObject*)type_obj)->tp_dict, __pyx_n_s_setstate_cython); if (unlikely(ret < 0)) goto __PYX_BAD;
                } else if (!setstate || PyErr_Occurred()) {
                    goto __PYX_BAD;
                }
            }
            PyType_Modified((PyTypeObject*)type_obj);
        }
    }
    goto __PYX_GOOD;
__PYX_BAD:
    if (!PyErr_Occurred())
        PyErr_Format(PyExc_RuntimeError, "Unable to initialize pickling for %s", ((PyTypeObject*)type_obj)->tp_name);
    ret = -1;
__PYX_GOOD:
#if !CYTHON_USE_PYTYPE_LOOKUP
    Py_XDECREF(object_reduce);
    Py_XDECREF(object_reduce_ex);
#endif
    Py_XDECREF(reduce);
    Py_XDECREF(reduce_ex);
    Py_XDECREF(reduce_cython);
    Py_XDECREF(setstate);
    Py_XDECREF(setstate_cython);
    return ret;
}

/* PyObject_GenericGetAttr */
#if CYTHON_USE_TYPE_SLOTS && CYTHON_USE_PYTYPE_LOOKUP && PY_VERSION_HEX < 0x03070000
static PyObject* __Pyx_PyObject_GenericGetAttr(PyObject* obj, PyObject* attr_name) {
    if (unlikely(Py_TYPE(obj)->tp_dictoffset)) {
        return PyObject_GenericGetAttr(obj, attr_name);
    }
    return __Pyx_PyObject_GenericGetAttrNoDict(obj, attr_name);
}
#endif

/* CLineInTraceback */
#ifndef CYTHON_CLINE_IN_TRACEBACK
static int __Pyx_CLineForTraceback(CYTHON_NCP_UNUSED PyThreadState *tstate, int c_line) {
    PyObject *use_cline;
    PyObject *ptype, *pvalue, *ptraceback;
#if CYTHON_COMPILING_IN_CPYTHON
    PyObject **cython_runtime_dict;
#endif
    if (unlikely(!__pyx_cython_runtime)) {
        return c_line;
    }
    __Pyx_ErrFetchInState(tstate, &ptype, &pvalue, &ptraceback);
#if CYTHON_COMPILING_IN_CPYTHON
    cython_runtime_dict = _PyObject_GetDictPtr(__pyx_cython_runtime);
    if (likely(cython_runtime_dict)) {
        __PYX_PY_DICT_LOOKUP_IF_MODIFIED(
            use_cline, *cython_runtime_dict,
            __Pyx_PyDict_GetItemStr(*cython_runtime_dict, __pyx_n_s_cline_in_traceback))
    } else
#endif
    {
      PyObject *use_cline_obj = __Pyx_PyObject_GetAttrStr(__pyx_cython_runtime, __pyx_n_s_cline_in_traceback);
      if (use_cline_obj) {
        use_cline = PyObject_Not(use_cline_obj) ? Py_False : Py_True;
        Py_DECREF(use_cline_obj);
      } else {
        PyErr_Clear();
        use_cline = NULL;
      }
    }
    if (!use_cline) {
        c_line = 0;
        PyObject_SetAttr(__pyx_cython_runtime, __pyx_n_s_cline_in_traceback, Py_False);
    }
    else if (use_cline == Py_False || (use_cline != Py_True && PyObject_Not(use_cline) != 0)) {
        c_line = 0;
    }
    __Pyx_ErrRestoreInState(tstate, ptype, pvalue, ptraceback);
    return c_line;
}
#endif

/* CodeObjectCache */
static int __pyx_bisect_code_objects(__Pyx_CodeObjectCacheEntry* entries, int count, int code_line) {
    int start = 0, mid = 0, end = count - 1;
    if (end >= 0 && code_line > entries[end].code_line) {
        return count;
    }
    while (start < end) {
        mid = start + (end - start) / 2;
        if (code_line < entries[mid].code_line) {
            end = mid;
        } else if (code_line > entries[mid].code_line) {
             start = mid + 1;
        } else {
            return mid;
        }
    }
    if (code_line <= entries[mid].code_line) {
        return mid;
    } else {
        return mid + 1;
    }
}
static PyCodeObject *__pyx_find_code_object(int code_line) {
    PyCodeObject* code_object;
    int pos;
    if (unlikely(!code_line) || unlikely(!__pyx_code_cache.entries)) {
        return NULL;
    }
    pos = __pyx_bisect_code_objects(__pyx_code_cache.entries, __pyx_code_cache.count, code_line);
    if (unlikely(pos >= __pyx_code_cache.count) || unlikely(__pyx_code_cache.entries[pos].code_line != code_line)) {
        return NULL;
    }
    code_object = __pyx_code_cache.entries[pos].code_object;
    Py_INCREF(code_object);
    return code_object;
}
static void __pyx_insert_code_object(int code_line, PyCodeObject* code_object) {
    int pos, i;
    __Pyx_CodeObjectCacheEntry* entries = __pyx_code_cache.entries;
    if (unlikely(!code_line)) {
        return;
    }
    if (unlikely(!entries)) {
        entries = (__Pyx_CodeObjectCacheEntry*)PyMem_Malloc(64*sizeof(__Pyx_CodeObjectCacheEntry));
        if (likely(entries)) {
            __pyx_code_cache.entries = entries;
            __pyx_code_cache.max_count = 64;
            __pyx_code_cache.count = 1;
            entries[0].code_line = code_line;
            entries[0].code_object = code_object;
            Py_INCREF(code_object);
        }
        return;
    }
    pos = __pyx_bisect_code_objects(__pyx_code_cache.entries, __pyx_code_cache.count, code_line);
    if ((pos < __pyx_code_cache.count) && unlikely(__pyx_code_cache.entries[pos].code_line == code_line)) {
        PyCodeObject* tmp = entries[pos].code_object;
        entries[pos].code_object = code_object;
        Py_DECREF(tmp);
        return;
    }
    if (__pyx_code_cache.count == __pyx_code_cache.max_count) {
        int new_max = __pyx_code_cache.max_count + 64;
        entries = (__Pyx_CodeObjectCacheEntry*)PyMem_Realloc(
            __pyx_code_cache.entries, ((size_t)new_max) * sizeof(__Pyx_CodeObjectCacheEntry));
        if (unlikely(!entries)) {
            return;
        }
        __pyx_code_cache.entries = entries;
        __pyx_code_cache.max_count = new_max;
    }
    for (i=__pyx_code_cache.count; i>pos; i--) {
        entries[i] = entries[i-1];
    }
    entries[pos].code_line = code_line;
    entries[pos].code_object = code_object;
    __pyx_code_cache.count++;
    Py_INCREF(code_object);
}

/* AddTraceback */
#include "compile.h"
#include "frameobject.h"
#include "traceback.h"
static PyCodeObject* __Pyx_CreateCodeObjectForTraceback(
            const char *funcname, int c_line,
            int py_line, const char *filename) {
    PyCodeObject *py_code = 0;
    PyObject *py_srcfile = 0;
    PyObject *py_funcname = 0;
    #if PY_MAJOR_VERSION < 3
    py_srcfile = PyString_FromString(filename);
    #else
    py_srcfile = PyUnicode_FromString(filename);
    #endif
    if (!py_srcfile) goto bad;
    if (c_line) {
        #if PY_MAJOR_VERSION < 3
        py_funcname = PyString_FromFormat( "%s (%s:%d)", funcname, __pyx_cfilenm, c_line);
        #else
        py_funcname = PyUnicode_FromFormat( "%s (%s:%d)", funcname, __pyx_cfilenm, c_line);
        #endif
    }
    else {
        #if PY_MAJOR_VERSION < 3
        py_funcname = PyString_FromString(funcname);
        #else
        py_funcname = PyUnicode_FromString(funcname);
        #endif
    }
    if (!py_funcname) goto bad;
    py_code = __Pyx_PyCode_New(
        0,
        0,
        0,
        0,
        0,
        __pyx_empty_bytes, /*PyObject *code,*/
        __pyx_empty_tuple, /*PyObject *consts,*/
        __pyx_empty_tuple, /*PyObject *names,*/
        __pyx_empty_tuple, /*PyObject *varnames,*/
        __pyx_empty_tuple, /*PyObject *freevars,*/
        __pyx_empty_tuple, /*PyObject *cellvars,*/
        py_srcfile,   /*PyObject *filename,*/
        py_funcname,  /*PyObject *name,*/
        py_line,
        __pyx_empty_bytes  /*PyObject *lnotab*/
    );
    Py_DECREF(py_srcfile);
    Py_DECREF(py_funcname);
    return py_code;
bad:
    Py_XDECREF(py_srcfile);
    Py_XDECREF(py_funcname);
    return NULL;
}
static void __Pyx_AddTraceback(const char *funcname, int c_line,
                               int py_line, const char *filename) {
    PyCodeObject *py_code = 0;
    PyFrameObject *py_frame = 0;
    PyThreadState *tstate = __Pyx_PyThreadState_Current;
    if (c_line) {
        c_line = __Pyx_CLineForTraceback(tstate, c_line);
    }
    py_code = __pyx_find_code_object(c_line ? -c_line : py_line);
    if (!py_code) {
        py_code = __Pyx_CreateCodeObjectForTraceback(
            funcname, c_line, py_line, filename);
        if (!py_code) goto bad;
        __pyx_insert_code_object(c_line ? -c_line : py_line, py_code);
    }
    py_frame = PyFrame_New(
        tstate,            /*PyThreadState *tstate,*/
        py_code,           /*PyCodeObject *code,*/
        __pyx_d,    /*PyObject *globals,*/
        0                  /*PyObject *locals*/
    );
    if (!py_frame) goto bad;
    __Pyx_PyFrame_SetLineNumber(py_frame, py_line);
    PyTraceBack_Here(py_frame);
bad:
    Py_XDECREF(py_code);
    Py_XDECREF(py_frame);
}

/* CIntToPy */
static CYTHON_INLINE PyObject* __Pyx_PyInt_From_long(long value) {
    const long neg_one = (long) ((long) 0 - (long) 1), const_zero = (long) 0;
    const int is_unsigned = neg_one > const_zero;
    if (is_unsigned) {
        if (sizeof(long) < sizeof(long)) {
            return PyInt_FromLong((long) value);
        } else if (sizeof(long) <= sizeof(unsigned long)) {
            return PyLong_FromUnsignedLong((unsigned long) value);
#ifdef HAVE_LONG_LONG
        } else if (sizeof(long) <= sizeof(unsigned PY_LONG_LONG)) {
            return PyLong_FromUnsignedLongLong((unsigned PY_LONG_LONG) value);
#endif
        }
    } else {
        if (sizeof(long) <= sizeof(long)) {
            return PyInt_FromLong((long) value);
#ifdef HAVE_LONG_LONG
        } else if (sizeof(long) <= sizeof(PY_LONG_LONG)) {
            return PyLong_FromLongLong((PY_LONG_LONG) value);
#endif
        }
    }
    {
        int one = 1; int little = (int)*(unsigned char *)&one;
        unsigned char *bytes = (unsigned char *)&value;
        return _PyLong_FromByteArray(bytes, sizeof(long),
                                     little, !is_unsigned);
    }
}

/* CIntFromPyVerify */
#define __PYX_VERIFY_RETURN_INT(target_type, func_type, func_value)\
    __PYX__VERIFY_RETURN_INT(target_type, func_type, func_value, 0)
#define __PYX_VERIFY_RETURN_INT_EXC(target_type, func_type, func_value)\
    __PYX__VERIFY_RETURN_INT(target_type, func_type, func_value, 1)
#define __PYX__VERIFY_RETURN_INT(target_type, func_type, func_value, exc)\
    {\
        func_type value = func_value;\
        if (sizeof(target_type) < sizeof(func_type)) {\
            if (unlikely(value != (func_type) (target_type) value)) {\
                func_type zero = 0;\
                if (exc && unlikely(value == (func_type)-1 && PyErr_Occurred()))\
                    return (target_type) -1;\
                if (is_unsigned && unlikely(value < zero))\
                    goto raise_neg_overflow;\
                else\
                    goto raise_overflow;\
            }\
        }\
        return (target_type) value;\
    }

/* Declarations */
#if CYTHON_CCOMPLEX
  #ifdef __cplusplus
    static CYTHON_INLINE __pyx_t_float_complex __pyx_t_float_complex_from_parts(float x, float y) {
      return ::std::complex< float >(x, y);
    }
  #else
    static CYTHON_INLINE __pyx_t_float_complex __pyx_t_float_complex_from_parts(float x, float y) {
      return x + y*(__pyx_t_float_complex)_Complex_I;
    }
  #endif
#else
    static CYTHON_INLINE __pyx_t_float_complex __pyx_t_float_complex_from_parts(float x, float y) {
      __pyx_t_float_complex z;
      z.real = x;
      z.imag = y;
      return z;
    }
#endif

/* Arithmetic */
#if CYTHON_CCOMPLEX
#else
    static CYTHON_INLINE int __Pyx_c_eq_float(__pyx_t_float_complex a, __pyx_t_float_complex b) {
       return (a.real == b.real) && (a.imag == b.imag);
    }
    static CYTHON_INLINE __pyx_t_float_complex __Pyx_c_sum_float(__pyx_t_float_complex a, __pyx_t_float_complex b) {
        __pyx_t_float_complex z;
        z.real = a.real + b.real;
        z.imag = a.imag + b.imag;
        return z;
    }
    static CYTHON_INLINE __pyx_t_float_complex __Pyx_c_diff_float(__pyx_t_float_complex a, __pyx_t_float_complex b) {
        __pyx_t_float_complex z;
        z.real = a.real - b.real;
        z.imag = a.imag - b.imag;
        return z;
    }
    static CYTHON_INLINE __pyx_t_float_complex __Pyx_c_prod_float(__pyx_t_float_complex a, __pyx_t_float_complex b) {
        __pyx_t_float_complex z;
        z.real = a.real * b.real - a.imag * b.imag;
        z.imag = a.real * b.imag + a.imag * b.real;
        return z;
    }
    #if 1
    static CYTHON_INLINE __pyx_t_float_complex __Pyx_c_quot_float(__pyx_t_float_complex a, __pyx_t_float_complex b) {
        if (b.imag == 0) {
            return __pyx_t_float_complex_from_parts(a.real / b.real, a.imag / b.real);
        } else if (fabsf(b.real) >= fabsf(b.imag)) {
            if (b.real == 0 && b.imag == 0) {
                return __pyx_t_float_complex_from_parts(a.real / b.real, a.imag / b.imag);
            } else {
                float r = b.imag / b.real;
                float s = (float)(1.0) / (b.real + b.imag * r);
                return __pyx_t_float_complex_from_parts(
                    (a.real + a.imag * r) * s, (a.imag - a.real * r) * s);
            }
        } else {
            float r = b.real / b.imag;
            float s = (float)(1.0) / (b.imag + b.real * r);
            return __pyx_t_float_complex_from_parts(
                (a.real * r + a.imag) * s, (a.imag * r - a.real) * s);
        }
    }
    #else
    static CYTHON_INLINE __pyx_t_float_complex __Pyx_c_quot_float(__pyx_t_float_complex a, __pyx_t_float_complex b) {
        if (b.imag == 0) {
            return __pyx_t_float_complex_from_parts(a.real / b.real, a.imag / b.real);
        } else {
            float denom = b.real * b.real + b.imag * b.imag;
            return __pyx_t_float_complex_from_parts(
                (a.real * b.real + a.imag * b.imag) / denom,
                (a.imag * b.real - a.real * b.imag) / denom);
        }
    }
    #endif
    static CYTHON_INLINE __pyx_t_float_complex __Pyx_c_neg_float(__pyx_t_float_complex a) {
        __pyx_t_float_complex z;
        z.real = -a.real;
        z.imag = -a.imag;
        return z;
    }
    static CYTHON_INLINE int __Pyx_c_is_zero_float(__pyx_t_float_complex a) {
       return (a.real == 0) && (a.imag == 0);
    }
    static CYTHON_INLINE __pyx_t_float_complex __Pyx_c_conj_float(__pyx_t_float_complex a) {
        __pyx_t_float_complex z;
        z.real =  a.real;
        z.imag = -a.imag;
        return z;
    }
    #if 1
        static CYTHON_INLINE float __Pyx_c_abs_float(__pyx_t_float_complex z) {
          #if !defined(HAVE_HYPOT) || defined(_MSC_VER)
            return sqrtf(z.real*z.real + z.imag*z.imag);
          #else
            return hypotf(z.real, z.imag);
          #endif
        }
        static CYTHON_INLINE __pyx_t_float_complex __Pyx_c_pow_float(__pyx_t_float_complex a, __pyx_t_float_complex b) {
            __pyx_t_float_complex z;
            float r, lnr, theta, z_r, z_theta;
            if (b.imag == 0 && b.real == (int)b.real) {
                if (b.real < 0) {
                    float denom = a.real * a.real + a.imag * a.imag;
                    a.real = a.real / denom;
                    a.imag = -a.imag / denom;
                    b.real = -b.real;
                }
                switch ((int)b.real) {
                    case 0:
                        z.real = 1;
                        z.imag = 0;
                        return z;
                    case 1:
                        return a;
                    case 2:
                        return __Pyx_c_prod_float(a, a);
                    case 3:
                        z = __Pyx_c_prod_float(a, a);
                        return __Pyx_c_prod_float(z, a);
                    case 4:
                        z = __Pyx_c_prod_float(a, a);
                        return __Pyx_c_prod_float(z, z);
                }
            }
            if (a.imag == 0) {
                if (a.real == 0) {
                    return a;
                } else if (b.imag == 0) {
                    z.real = powf(a.real, b.real);
                    z.imag = 0;
                    return z;
                } else if (a.real > 0) {
                    r = a.real;
                    theta = 0;
                } else {
                    r = -a.real;
                    theta = atan2f(0.0, -1.0);
                }
            } else {
                r = __Pyx_c_abs_float(a);
                theta = atan2f(a.imag, a.real);
            }
            lnr = logf(r);
            z_r = expf(lnr * b.real - theta * b.imag);
            z_theta = theta * b.real + lnr * b.imag;
            z.real = z_r * cosf(z_theta);
            z.imag = z_r * sinf(z_theta);
            return z;
        }
    #endif
#endif

/* Declarations */
#if CYTHON_CCOMPLEX
  #ifdef __cplusplus
    static CYTHON_INLINE __pyx_t_double_complex __pyx_t_double_complex_from_parts(double x, double y) {
      return ::std::complex< double >(x, y);
    }
  #else
    static CYTHON_INLINE __pyx_t_double_complex __pyx_t_double_complex_from_parts(double x, double y) {
      return x + y*(__pyx_t_double_complex)_Complex_I;
    }
  #endif
#else
    static CYTHON_INLINE __pyx_t_double_complex __pyx_t_double_complex_from_parts(double x, double y) {
      __pyx_t_double_complex z;
      z.real = x;
      z.imag = y;
      return z;
    }
#endif

/* Arithmetic */
#if CYTHON_CCOMPLEX
#else
    static CYTHON_INLINE int __Pyx_c_eq_double(__pyx_t_double_complex a, __pyx_t_double_complex b) {
       return (a.real == b.real) && (a.imag == b.imag);
    }
    static CYTHON_INLINE __pyx_t_double_complex __Pyx_c_sum_double(__pyx_t_double_complex a, __pyx_t_double_complex b) {
        __pyx_t_double_complex z;
        z.real = a.real + b.real;
        z.imag = a.imag + b.imag;
        return z;
    }
    static CYTHON_INLINE __pyx_t_double_complex __Pyx_c_diff_double(__pyx_t_double_complex a, __pyx_t_double_complex b) {
        __pyx_t_double_complex z;
        z.real = a.real - b.real;
        z.imag = a.imag - b.imag;
        return z;
    }
    static CYTHON_INLINE __pyx_t_double_complex __Pyx_c_prod_double(__pyx_t_double_complex a, __pyx_t_double_complex b) {
        __pyx_t_double_complex z;
        z.real = a.real * b.real - a.imag * b.imag;
        z.imag = a.real * b.imag + a.imag * b.real;
        return z;
    }
    #if 1
    static CYTHON_INLINE __pyx_t_double_complex __Pyx_c_quot_double(__pyx_t_double_complex a, __pyx_t_double_complex b) {
        if (b.imag == 0) {
            return __pyx_t_double_complex_from_parts(a.real / b.real, a.imag / b.real);
        } else if (fabs(b.real) >= fabs(b.imag)) {
            if (b.real == 0 && b.imag == 0) {
                return __pyx_t_double_complex_from_parts(a.real / b.real, a.imag / b.imag);
            } else {
                double r = b.imag / b.real;
                double s = (double)(1.0) / (b.real + b.imag * r);
                return __pyx_t_double_complex_from_parts(
                    (a.real + a.imag * r) * s, (a.imag - a.real * r) * s);
            }
        } else {
            double r = b.real / b.imag;
            double s = (double)(1.0) / (b.imag + b.real * r);
            return __pyx_t_double_complex_from_parts(
                (a.real * r + a.imag) * s, (a.imag * r - a.real) * s);
        }
    }
    #else
    static CYTHON_INLINE __pyx_t_double_complex __Pyx_c_quot_double(__pyx_t_double_complex a, __pyx_t_double_complex b) {
        if (b.imag == 0) {
            return __pyx_t_double_complex_from_parts(a.real / b.real, a.imag / b.real);
        } else {
            double denom = b.real * b.real + b.imag * b.imag;
            return __pyx_t_double_complex_from_parts(
                (a.real * b.real + a.imag * b.imag) / denom,
                (a.imag * b.real - a.real * b.imag) / denom);
        }
    }
    #endif
    static CYTHON_INLINE __pyx_t_double_complex __Pyx_c_neg_double(__pyx_t_double_complex a) {
        __pyx_t_double_complex z;
        z.real = -a.real;
        z.imag = -a.imag;
        return z;
    }
    static CYTHON_INLINE int __Pyx_c_is_zero_double(__pyx_t_double_complex a) {
       return (a.real == 0) && (a.imag == 0);
    }
    static CYTHON_INLINE __pyx_t_double_complex __Pyx_c_conj_double(__pyx_t_double_complex a) {
        __pyx_t_double_complex z;
        z.real =  a.real;
        z.imag = -a.imag;
        return z;
    }
    #if 1
        static CYTHON_INLINE double __Pyx_c_abs_double(__pyx_t_double_complex z) {
          #if !defined(HAVE_HYPOT) || defined(_MSC_VER)
            return sqrt(z.real*z.real + z.imag*z.imag);
          #else
            return hypot(z.real, z.imag);
          #endif
        }
        static CYTHON_INLINE __pyx_t_double_complex __Pyx_c_pow_double(__pyx_t_double_complex a, __pyx_t_double_complex b) {
            __pyx_t_double_complex z;
            double r, lnr, theta, z_r, z_theta;
            if (b.imag == 0 && b.real == (int)b.real) {
                if (b.real < 0) {
                    double denom = a.real * a.real + a.imag * a.imag;
                    a.real = a.real / denom;
                    a.imag = -a.imag / denom;
                    b.real = -b.real;
                }
                switch ((int)b.real) {
                    case 0:
                        z.real = 1;
                        z.imag = 0;
                        return z;
                    case 1:
                        return a;
                    case 2:
                        return __Pyx_c_prod_double(a, a);
                    case 3:
                        z = __Pyx_c_prod_double(a, a);
                        return __Pyx_c_prod_double(z, a);
                    case 4:
                        z = __Pyx_c_prod_double(a, a);
                        return __Pyx_c_prod_double(z, z);
                }
            }
            if (a.imag == 0) {
                if (a.real == 0) {
                    return a;
                } else if (b.imag == 0) {
                    z.real = pow(a.real, b.real);
                    z.imag = 0;
                    return z;
                } else if (a.real > 0) {
                    r = a.real;
                    theta = 0;
                } else {
                    r = -a.real;
                    theta = atan2(0.0, -1.0);
                }
            } else {
                r = __Pyx_c_abs_double(a);
                theta = atan2(a.imag, a.real);
            }
            lnr = log(r);
            z_r = exp(lnr * b.real - theta * b.imag);
            z_theta = theta * b.real + lnr * b.imag;
            z.real = z_r * cos(z_theta);
            z.imag = z_r * sin(z_theta);
            return z;
        }
    #endif
#endif

/* CIntFromPy */
static CYTHON_INLINE long __Pyx_PyInt_As_long(PyObject *x) {
    const long neg_one = (long) ((long) 0 - (long) 1), const_zero = (long) 0;
    const int is_unsigned = neg_one > const_zero;
#if PY_MAJOR_VERSION < 3
    if (likely(PyInt_Check(x))) {
        if (sizeof(long) < sizeof(long)) {
            __PYX_VERIFY_RETURN_INT(long, long, PyInt_AS_LONG(x))
        } else {
            long val = PyInt_AS_LONG(x);
            if (is_unsigned && unlikely(val < 0)) {
                goto raise_neg_overflow;
            }
            return (long) val;
        }
    } else
#endif
    if (likely(PyLong_Check(x))) {
        if (is_unsigned) {
#if CYTHON_USE_PYLONG_INTERNALS
            const digit* digits = ((PyLongObject*)x)->ob_digit;
            switch (Py_SIZE(x)) {
                case  0: return (long) 0;
                case  1: __PYX_VERIFY_RETURN_INT(long, digit, digits[0])
                case 2:
                    if (8 * sizeof(long) > 1 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 2 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(long, unsigned long, (((((unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(long) >= 2 * PyLong_SHIFT) {
                            return (long) (((((long)digits[1]) << PyLong_SHIFT) | (long)digits[0]));
                        }
                    }
                    break;
                case 3:
                    if (8 * sizeof(long) > 2 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 3 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(long, unsigned long, (((((((unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(long) >= 3 * PyLong_SHIFT) {
                            return (long) (((((((long)digits[2]) << PyLong_SHIFT) | (long)digits[1]) << PyLong_SHIFT) | (long)digits[0]));
                        }
                    }
                    break;
                case 4:
                    if (8 * sizeof(long) > 3 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 4 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(long, unsigned long, (((((((((unsigned long)digits[3]) << PyLong_SHIFT) | (unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(long) >= 4 * PyLong_SHIFT) {
                            return (long) (((((((((long)digits[3]) << PyLong_SHIFT) | (long)digits[2]) << PyLong_SHIFT) | (long)digits[1]) << PyLong_SHIFT) | (long)digits[0]));
                        }
                    }
                    break;
            }
#endif
#if CYTHON_COMPILING_IN_CPYTHON
            if (unlikely(Py_SIZE(x) < 0)) {
                goto raise_neg_overflow;
            }
#else
            {
                int result = PyObject_RichCompareBool(x, Py_False, Py_LT);
                if (unlikely(result < 0))
                    return (long) -1;
                if (unlikely(result == 1))
                    goto raise_neg_overflow;
            }
#endif
            if (sizeof(long) <= sizeof(unsigned long)) {
                __PYX_VERIFY_RETURN_INT_EXC(long, unsigned long, PyLong_AsUnsignedLong(x))
#ifdef HAVE_LONG_LONG
            } else if (sizeof(long) <= sizeof(unsigned PY_LONG_LONG)) {
                __PYX_VERIFY_RETURN_INT_EXC(long, unsigned PY_LONG_LONG, PyLong_AsUnsignedLongLong(x))
#endif
            }
        } else {
#if CYTHON_USE_PYLONG_INTERNALS
            const digit* digits = ((PyLongObject*)x)->ob_digit;
            switch (Py_SIZE(x)) {
                case  0: return (long) 0;
                case -1: __PYX_VERIFY_RETURN_INT(long, sdigit, (sdigit) (-(sdigit)digits[0]))
                case  1: __PYX_VERIFY_RETURN_INT(long,  digit, +digits[0])
                case -2:
                    if (8 * sizeof(long) - 1 > 1 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 2 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(long, long, -(long) (((((unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(long) - 1 > 2 * PyLong_SHIFT) {
                            return (long) (((long)-1)*(((((long)digits[1]) << PyLong_SHIFT) | (long)digits[0])));
                        }
                    }
                    break;
                case 2:
                    if (8 * sizeof(long) > 1 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 2 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(long, unsigned long, (((((unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(long) - 1 > 2 * PyLong_SHIFT) {
                            return (long) ((((((long)digits[1]) << PyLong_SHIFT) | (long)digits[0])));
                        }
                    }
                    break;
                case -3:
                    if (8 * sizeof(long) - 1 > 2 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 3 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(long, long, -(long) (((((((unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(long) - 1 > 3 * PyLong_SHIFT) {
                            return (long) (((long)-1)*(((((((long)digits[2]) << PyLong_SHIFT) | (long)digits[1]) << PyLong_SHIFT) | (long)digits[0])));
                        }
                    }
                    break;
                case 3:
                    if (8 * sizeof(long) > 2 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 3 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(long, unsigned long, (((((((unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(long) - 1 > 3 * PyLong_SHIFT) {
                            return (long) ((((((((long)digits[2]) << PyLong_SHIFT) | (long)digits[1]) << PyLong_SHIFT) | (long)digits[0])));
                        }
                    }
                    break;
                case -4:
                    if (8 * sizeof(long) - 1 > 3 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 4 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(long, long, -(long) (((((((((unsigned long)digits[3]) << PyLong_SHIFT) | (unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(long) - 1 > 4 * PyLong_SHIFT) {
                            return (long) (((long)-1)*(((((((((long)digits[3]) << PyLong_SHIFT) | (long)digits[2]) << PyLong_SHIFT) | (long)digits[1]) << PyLong_SHIFT) | (long)digits[0])));
                        }
                    }
                    break;
                case 4:
                    if (8 * sizeof(long) > 3 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 4 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(long, unsigned long, (((((((((unsigned long)digits[3]) << PyLong_SHIFT) | (unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(long) - 1 > 4 * PyLong_SHIFT) {
                            return (long) ((((((((((long)digits[3]) << PyLong_SHIFT) | (long)digits[2]) << PyLong_SHIFT) | (long)digits[1]) << PyLong_SHIFT) | (long)digits[0])));
                        }
                    }
                    break;
            }
#endif
            if (sizeof(long) <= sizeof(long)) {
                __PYX_VERIFY_RETURN_INT_EXC(long, long, PyLong_AsLong(x))
#ifdef HAVE_LONG_LONG
            } else if (sizeof(long) <= sizeof(PY_LONG_LONG)) {
                __PYX_VERIFY_RETURN_INT_EXC(long, PY_LONG_LONG, PyLong_AsLongLong(x))
#endif
            }
        }
        {
#if CYTHON_COMPILING_IN_PYPY && !defined(_PyLong_AsByteArray)
            PyErr_SetString(PyExc_RuntimeError,
                            "_PyLong_AsByteArray() not available in PyPy, cannot convert large numbers");
#else
            long val;
            PyObject *v = __Pyx_PyNumber_IntOrLong(x);
 #if PY_MAJOR_VERSION < 3
            if (likely(v) && !PyLong_Check(v)) {
                PyObject *tmp = v;
                v = PyNumber_Long(tmp);
                Py_DECREF(tmp);
            }
 #endif
            if (likely(v)) {
                int one = 1; int is_little = (int)*(unsigned char *)&one;
                unsigned char *bytes = (unsigned char *)&val;
                int ret = _PyLong_AsByteArray((PyLongObject *)v,
                                              bytes, sizeof(val),
                                              is_little, !is_unsigned);
                Py_DECREF(v);
                if (likely(!ret))
                    return val;
            }
#endif
            return (long) -1;
        }
    } else {
        long val;
        PyObject *tmp = __Pyx_PyNumber_IntOrLong(x);
        if (!tmp) return (long) -1;
        val = __Pyx_PyInt_As_long(tmp);
        Py_DECREF(tmp);
        return val;
    }
raise_overflow:
    PyErr_SetString(PyExc_OverflowError,
        "value too large to convert to long");
    return (long) -1;
raise_neg_overflow:
    PyErr_SetString(PyExc_OverflowError,
        "can't convert negative value to long");
    return (long) -1;
}

/* CIntFromPy */
static CYTHON_INLINE size_t __Pyx_PyInt_As_size_t(PyObject *x) {
    const size_t neg_one = (size_t) ((size_t) 0 - (size_t) 1), const_zero = (size_t) 0;
    const int is_unsigned = neg_one > const_zero;
#if PY_MAJOR_VERSION < 3
    if (likely(PyInt_Check(x))) {
        if (sizeof(size_t) < sizeof(long)) {
            __PYX_VERIFY_RETURN_INT(size_t, long, PyInt_AS_LONG(x))
        } else {
            long val = PyInt_AS_LONG(x);
            if (is_unsigned && unlikely(val < 0)) {
                goto raise_neg_overflow;
            }
            return (size_t) val;
        }
    } else
#endif
    if (likely(PyLong_Check(x))) {
        if (is_unsigned) {
#if CYTHON_USE_PYLONG_INTERNALS
            const digit* digits = ((PyLongObject*)x)->ob_digit;
            switch (Py_SIZE(x)) {
                case  0: return (size_t) 0;
                case  1: __PYX_VERIFY_RETURN_INT(size_t, digit, digits[0])
                case 2:
                    if (8 * sizeof(size_t) > 1 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 2 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(size_t, unsigned long, (((((unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(size_t) >= 2 * PyLong_SHIFT) {
                            return (size_t) (((((size_t)digits[1]) << PyLong_SHIFT) | (size_t)digits[0]));
                        }
                    }
                    break;
                case 3:
                    if (8 * sizeof(size_t) > 2 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 3 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(size_t, unsigned long, (((((((unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(size_t) >= 3 * PyLong_SHIFT) {
                            return (size_t) (((((((size_t)digits[2]) << PyLong_SHIFT) | (size_t)digits[1]) << PyLong_SHIFT) | (size_t)digits[0]));
                        }
                    }
                    break;
                case 4:
                    if (8 * sizeof(size_t) > 3 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 4 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(size_t, unsigned long, (((((((((unsigned long)digits[3]) << PyLong_SHIFT) | (unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(size_t) >= 4 * PyLong_SHIFT) {
                            return (size_t) (((((((((size_t)digits[3]) << PyLong_SHIFT) | (size_t)digits[2]) << PyLong_SHIFT) | (size_t)digits[1]) << PyLong_SHIFT) | (size_t)digits[0]));
                        }
                    }
                    break;
            }
#endif
#if CYTHON_COMPILING_IN_CPYTHON
            if (unlikely(Py_SIZE(x) < 0)) {
                goto raise_neg_overflow;
            }
#else
            {
                int result = PyObject_RichCompareBool(x, Py_False, Py_LT);
                if (unlikely(result < 0))
                    return (size_t) -1;
                if (unlikely(result == 1))
                    goto raise_neg_overflow;
            }
#endif
            if (sizeof(size_t) <= sizeof(unsigned long)) {
                __PYX_VERIFY_RETURN_INT_EXC(size_t, unsigned long, PyLong_AsUnsignedLong(x))
#ifdef HAVE_LONG_LONG
            } else if (sizeof(size_t) <= sizeof(unsigned PY_LONG_LONG)) {
                __PYX_VERIFY_RETURN_INT_EXC(size_t, unsigned PY_LONG_LONG, PyLong_AsUnsignedLongLong(x))
#endif
            }
        } else {
#if CYTHON_USE_PYLONG_INTERNALS
            const digit* digits = ((PyLongObject*)x)->ob_digit;
            switch (Py_SIZE(x)) {
                case  0: return (size_t) 0;
                case -1: __PYX_VERIFY_RETURN_INT(size_t, sdigit, (sdigit) (-(sdigit)digits[0]))
                case  1: __PYX_VERIFY_RETURN_INT(size_t,  digit, +digits[0])
                case -2:
                    if (8 * sizeof(size_t) - 1 > 1 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 2 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(size_t, long, -(long) (((((unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(size_t) - 1 > 2 * PyLong_SHIFT) {
                            return (size_t) (((size_t)-1)*(((((size_t)digits[1]) << PyLong_SHIFT) | (size_t)digits[0])));
                        }
                    }
                    break;
                case 2:
                    if (8 * sizeof(size_t) > 1 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 2 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(size_t, unsigned long, (((((unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(size_t) - 1 > 2 * PyLong_SHIFT) {
                            return (size_t) ((((((size_t)digits[1]) << PyLong_SHIFT) | (size_t)digits[0])));
                        }
                    }
                    break;
                case -3:
                    if (8 * sizeof(size_t) - 1 > 2 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 3 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(size_t, long, -(long) (((((((unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(size_t) - 1 > 3 * PyLong_SHIFT) {
                            return (size_t) (((size_t)-1)*(((((((size_t)digits[2]) << PyLong_SHIFT) | (size_t)digits[1]) << PyLong_SHIFT) | (size_t)digits[0])));
                        }
                    }
                    break;
                case 3:
                    if (8 * sizeof(size_t) > 2 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 3 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(size_t, unsigned long, (((((((unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(size_t) - 1 > 3 * PyLong_SHIFT) {
                            return (size_t) ((((((((size_t)digits[2]) << PyLong_SHIFT) | (size_t)digits[1]) << PyLong_SHIFT) | (size_t)digits[0])));
                        }
                    }
                    break;
                case -4:
                    if (8 * sizeof(size_t) - 1 > 3 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 4 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(size_t, long, -(long) (((((((((unsigned long)digits[3]) << PyLong_SHIFT) | (unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(size_t) - 1 > 4 * PyLong_SHIFT) {
                            return (size_t) (((size_t)-1)*(((((((((size_t)digits[3]) << PyLong_SHIFT) | (size_t)digits[2]) << PyLong_SHIFT) | (size_t)digits[1]) << PyLong_SHIFT) | (size_t)digits[0])));
                        }
                    }
                    break;
                case 4:
                    if (8 * sizeof(size_t) > 3 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 4 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(size_t, unsigned long, (((((((((unsigned long)digits[3]) << PyLong_SHIFT) | (unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(size_t) - 1 > 4 * PyLong_SHIFT) {
                            return (size_t) ((((((((((size_t)digits[3]) << PyLong_SHIFT) | (size_t)digits[2]) << PyLong_SHIFT) | (size_t)digits[1]) << PyLong_SHIFT) | (size_t)digits[0])));
                        }
                    }
                    break;
            }
#endif
            if (sizeof(size_t) <= sizeof(long)) {
                __PYX_VERIFY_RETURN_INT_EXC(size_t, long, PyLong_AsLong(x))
#ifdef HAVE_LONG_LONG
            } else if (sizeof(size_t) <= sizeof(PY_LONG_LONG)) {
                __PYX_VERIFY_RETURN_INT_EXC(size_t, PY_LONG_LONG, PyLong_AsLongLong(x))
#endif
            }
        }
        {
#if CYTHON_COMPILING_IN_PYPY && !defined(_PyLong_AsByteArray)
            PyErr_SetString(PyExc_RuntimeError,
                            "_PyLong_AsByteArray() not available in PyPy, cannot convert large numbers");
#else
            size_t val;
            PyObject *v = __Pyx_PyNumber_IntOrLong(x);
 #if PY_MAJOR_VERSION < 3
            if (likely(v) && !PyLong_Check(v)) {
                PyObject *tmp = v;
                v = PyNumber_Long(tmp);
                Py_DECREF(tmp);
            }
 #endif
            if (likely(v)) {
                int one = 1; int is_little = (int)*(unsigned char *)&one;
                unsigned char *bytes = (unsigned char *)&val;
                int ret = _PyLong_AsByteArray((PyLongObject *)v,
                                              bytes, sizeof(val),
                                              is_little, !is_unsigned);
                Py_DECREF(v);
                if (likely(!ret))
                    return val;
            }
#endif
            return (size_t) -1;
        }
    } else {
        size_t val;
        PyObject *tmp = __Pyx_PyNumber_IntOrLong(x);
        if (!tmp) return (size_t) -1;
        val = __Pyx_PyInt_As_size_t(tmp);
        Py_DECREF(tmp);
        return val;
    }
raise_overflow:
    PyErr_SetString(PyExc_OverflowError,
        "value too large to convert to size_t");
    return (size_t) -1;
raise_neg_overflow:
    PyErr_SetString(PyExc_OverflowError,
        "can't convert negative value to size_t");
    return (size_t) -1;
}

/* CIntFromPy */
static CYTHON_INLINE int __Pyx_PyInt_As_int(PyObject *x) {
    const int neg_one = (int) ((int) 0 - (int) 1), const_zero = (int) 0;
    const int is_unsigned = neg_one > const_zero;
#if PY_MAJOR_VERSION < 3
    if (likely(PyInt_Check(x))) {
        if (sizeof(int) < sizeof(long)) {
            __PYX_VERIFY_RETURN_INT(int, long, PyInt_AS_LONG(x))
        } else {
            long val = PyInt_AS_LONG(x);
            if (is_unsigned && unlikely(val < 0)) {
                goto raise_neg_overflow;
            }
            return (int) val;
        }
    } else
#endif
    if (likely(PyLong_Check(x))) {
        if (is_unsigned) {
#if CYTHON_USE_PYLONG_INTERNALS
            const digit* digits = ((PyLongObject*)x)->ob_digit;
            switch (Py_SIZE(x)) {
                case  0: return (int) 0;
                case  1: __PYX_VERIFY_RETURN_INT(int, digit, digits[0])
                case 2:
                    if (8 * sizeof(int) > 1 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 2 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(int, unsigned long, (((((unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(int) >= 2 * PyLong_SHIFT) {
                            return (int) (((((int)digits[1]) << PyLong_SHIFT) | (int)digits[0]));
                        }
                    }
                    break;
                case 3:
                    if (8 * sizeof(int) > 2 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 3 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(int, unsigned long, (((((((unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(int) >= 3 * PyLong_SHIFT) {
                            return (int) (((((((int)digits[2]) << PyLong_SHIFT) | (int)digits[1]) << PyLong_SHIFT) | (int)digits[0]));
                        }
                    }
                    break;
                case 4:
                    if (8 * sizeof(int) > 3 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 4 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(int, unsigned long, (((((((((unsigned long)digits[3]) << PyLong_SHIFT) | (unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(int) >= 4 * PyLong_SHIFT) {
                            return (int) (((((((((int)digits[3]) << PyLong_SHIFT) | (int)digits[2]) << PyLong_SHIFT) | (int)digits[1]) << PyLong_SHIFT) | (int)digits[0]));
                        }
                    }
                    break;
            }
#endif
#if CYTHON_COMPILING_IN_CPYTHON
            if (unlikely(Py_SIZE(x) < 0)) {
                goto raise_neg_overflow;
            }
#else
            {
                int result = PyObject_RichCompareBool(x, Py_False, Py_LT);
                if (unlikely(result < 0))
                    return (int) -1;
                if (unlikely(result == 1))
                    goto raise_neg_overflow;
            }
#endif
            if (sizeof(int) <= sizeof(unsigned long)) {
                __PYX_VERIFY_RETURN_INT_EXC(int, unsigned long, PyLong_AsUnsignedLong(x))
#ifdef HAVE_LONG_LONG
            } else if (sizeof(int) <= sizeof(unsigned PY_LONG_LONG)) {
                __PYX_VERIFY_RETURN_INT_EXC(int, unsigned PY_LONG_LONG, PyLong_AsUnsignedLongLong(x))
#endif
            }
        } else {
#if CYTHON_USE_PYLONG_INTERNALS
            const digit* digits = ((PyLongObject*)x)->ob_digit;
            switch (Py_SIZE(x)) {
                case  0: return (int) 0;
                case -1: __PYX_VERIFY_RETURN_INT(int, sdigit, (sdigit) (-(sdigit)digits[0]))
                case  1: __PYX_VERIFY_RETURN_INT(int,  digit, +digits[0])
                case -2:
                    if (8 * sizeof(int) - 1 > 1 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 2 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(int, long, -(long) (((((unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(int) - 1 > 2 * PyLong_SHIFT) {
                            return (int) (((int)-1)*(((((int)digits[1]) << PyLong_SHIFT) | (int)digits[0])));
                        }
                    }
                    break;
                case 2:
                    if (8 * sizeof(int) > 1 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 2 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(int, unsigned long, (((((unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(int) - 1 > 2 * PyLong_SHIFT) {
                            return (int) ((((((int)digits[1]) << PyLong_SHIFT) | (int)digits[0])));
                        }
                    }
                    break;
                case -3:
                    if (8 * sizeof(int) - 1 > 2 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 3 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(int, long, -(long) (((((((unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(int) - 1 > 3 * PyLong_SHIFT) {
                            return (int) (((int)-1)*(((((((int)digits[2]) << PyLong_SHIFT) | (int)digits[1]) << PyLong_SHIFT) | (int)digits[0])));
                        }
                    }
                    break;
                case 3:
                    if (8 * sizeof(int) > 2 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 3 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(int, unsigned long, (((((((unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(int) - 1 > 3 * PyLong_SHIFT) {
                            return (int) ((((((((int)digits[2]) << PyLong_SHIFT) | (int)digits[1]) << PyLong_SHIFT) | (int)digits[0])));
                        }
                    }
                    break;
                case -4:
                    if (8 * sizeof(int) - 1 > 3 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 4 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(int, long, -(long) (((((((((unsigned long)digits[3]) << PyLong_SHIFT) | (unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(int) - 1 > 4 * PyLong_SHIFT) {
                            return (int) (((int)-1)*(((((((((int)digits[3]) << PyLong_SHIFT) | (int)digits[2]) << PyLong_SHIFT) | (int)digits[1]) << PyLong_SHIFT) | (int)digits[0])));
                        }
                    }
                    break;
                case 4:
                    if (8 * sizeof(int) > 3 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 4 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(int, unsigned long, (((((((((unsigned long)digits[3]) << PyLong_SHIFT) | (unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(int) - 1 > 4 * PyLong_SHIFT) {
                            return (int) ((((((((((int)digits[3]) << PyLong_SHIFT) | (int)digits[2]) << PyLong_SHIFT) | (int)digits[1]) << PyLong_SHIFT) | (int)digits[0])));
                        }
                    }
                    break;
            }
#endif
            if (sizeof(int) <= sizeof(long)) {
                __PYX_VERIFY_RETURN_INT_EXC(int, long, PyLong_AsLong(x))
#ifdef HAVE_LONG_LONG
            } else if (sizeof(int) <= sizeof(PY_LONG_LONG)) {
                __PYX_VERIFY_RETURN_INT_EXC(int, PY_LONG_LONG, PyLong_AsLongLong(x))
#endif
            }
        }
        {
#if CYTHON_COMPILING_IN_PYPY && !defined(_PyLong_AsByteArray)
            PyErr_SetString(PyExc_RuntimeError,
                            "_PyLong_AsByteArray() not available in PyPy, cannot convert large numbers");
#else
            int val;
            PyObject *v = __Pyx_PyNumber_IntOrLong(x);
 #if PY_MAJOR_VERSION < 3
            if (likely(v) && !PyLong_Check(v)) {
                PyObject *tmp = v;
                v = PyNumber_Long(tmp);
                Py_DECREF(tmp);
            }
 #endif
            if (likely(v)) {
                int one = 1; int is_little = (int)*(unsigned char *)&one;
                unsigned char *bytes = (unsigned char *)&val;
                int ret = _PyLong_AsByteArray((PyLongObject *)v,
                                              bytes, sizeof(val),
                                              is_little, !is_unsigned);
                Py_DECREF(v);
                if (likely(!ret))
                    return val;
            }
#endif
            return (int) -1;
        }
    } else {
        int val;
        PyObject *tmp = __Pyx_PyNumber_IntOrLong(x);
        if (!tmp) return (int) -1;
        val = __Pyx_PyInt_As_int(tmp);
        Py_DECREF(tmp);
        return val;
    }
raise_overflow:
    PyErr_SetString(PyExc_OverflowError,
        "value too large to convert to int");
    return (int) -1;
raise_neg_overflow:
    PyErr_SetString(PyExc_OverflowError,
        "can't convert negative value to int");
    return (int) -1;
}

/* FastTypeChecks */
#if CYTHON_COMPILING_IN_CPYTHON
static int __Pyx_InBases(PyTypeObject *a, PyTypeObject *b) {
    while (a) {
        a = a->tp_base;
        if (a == b)
            return 1;
    }
    return b == &PyBaseObject_Type;
}
static CYTHON_INLINE int __Pyx_IsSubtype(PyTypeObject *a, PyTypeObject *b) {
    PyObject *mro;
    if (a == b) return 1;
    mro = a->tp_mro;
    if (likely(mro)) {
        Py_ssize_t i, n;
        n = PyTuple_GET_SIZE(mro);
        for (i = 0; i < n; i++) {
            if (PyTuple_GET_ITEM(mro, i) == (PyObject *)b)
                return 1;
        }
        return 0;
    }
    return __Pyx_InBases(a, b);
}
#if PY_MAJOR_VERSION == 2
static int __Pyx_inner_PyErr_GivenExceptionMatches2(PyObject *err, PyObject* exc_type1, PyObject* exc_type2) {
    PyObject *exception, *value, *tb;
    int res;
    __Pyx_PyThreadState_declare
    __Pyx_PyThreadState_assign
    __Pyx_ErrFetch(&exception, &value, &tb);
    res = exc_type1 ? PyObject_IsSubclass(err, exc_type1) : 0;
    if (unlikely(res == -1)) {
        PyErr_WriteUnraisable(err);
        res = 0;
    }
    if (!res) {
        res = PyObject_IsSubclass(err, exc_type2);
        if (unlikely(res == -1)) {
            PyErr_WriteUnraisable(err);
            res = 0;
        }
    }
    __Pyx_ErrRestore(exception, value, tb);
    return res;
}
#else
static CYTHON_INLINE int __Pyx_inner_PyErr_GivenExceptionMatches2(PyObject *err, PyObject* exc_type1, PyObject *exc_type2) {
    int res = exc_type1 ? __Pyx_IsSubtype((PyTypeObject*)err, (PyTypeObject*)exc_type1) : 0;
    if (!res) {
        res = __Pyx_IsSubtype((PyTypeObject*)err, (PyTypeObject*)exc_type2);
    }
    return res;
}
#endif
static int __Pyx_PyErr_GivenExceptionMatchesTuple(PyObject *exc_type, PyObject *tuple) {
    Py_ssize_t i, n;
    assert(PyExceptionClass_Check(exc_type));
    n = PyTuple_GET_SIZE(tuple);
#if PY_MAJOR_VERSION >= 3
    for (i=0; i<n; i++) {
        if (exc_type == PyTuple_GET_ITEM(tuple, i)) return 1;
    }
#endif
    for (i=0; i<n; i++) {
        PyObject *t = PyTuple_GET_ITEM(tuple, i);
        #if PY_MAJOR_VERSION < 3
        if (likely(exc_type == t)) return 1;
        #endif
        if (likely(PyExceptionClass_Check(t))) {
            if (__Pyx_inner_PyErr_GivenExceptionMatches2(exc_type, NULL, t)) return 1;
        } else {
        }
    }
    return 0;
}
static CYTHON_INLINE int __Pyx_PyErr_GivenExceptionMatches(PyObject *err, PyObject* exc_type) {
    if (likely(err == exc_type)) return 1;
    if (likely(PyExceptionClass_Check(err))) {
        if (likely(PyExceptionClass_Check(exc_type))) {
            return __Pyx_inner_PyErr_GivenExceptionMatches2(err, NULL, exc_type);
        } else if (likely(PyTuple_Check(exc_type))) {
            return __Pyx_PyErr_GivenExceptionMatchesTuple(err, exc_type);
        } else {
        }
    }
    return PyErr_GivenExceptionMatches(err, exc_type);
}
static CYTHON_INLINE int __Pyx_PyErr_GivenExceptionMatches2(PyObject *err, PyObject *exc_type1, PyObject *exc_type2) {
    assert(PyExceptionClass_Check(exc_type1));
    assert(PyExceptionClass_Check(exc_type2));
    if (likely(err == exc_type1 || err == exc_type2)) return 1;
    if (likely(PyExceptionClass_Check(err))) {
        return __Pyx_inner_PyErr_GivenExceptionMatches2(err, exc_type1, exc_type2);
    }
    return (PyErr_GivenExceptionMatches(err, exc_type1) || PyErr_GivenExceptionMatches(err, exc_type2));
}
#endif

/* CheckBinaryVersion */
static int __Pyx_check_binary_version(void) {
    char ctversion[4], rtversion[4];
    PyOS_snprintf(ctversion, 4, "%d.%d", PY_MAJOR_VERSION, PY_MINOR_VERSION);
    PyOS_snprintf(rtversion, 4, "%s", Py_GetVersion());
    if (ctversion[0] != rtversion[0] || ctversion[2] != rtversion[2]) {
        char message[200];
        PyOS_snprintf(message, sizeof(message),
                      "compiletime version %s of module '%.100s' "
                      "does not match runtime version %s",
                      ctversion, __Pyx_MODULE_NAME, rtversion);
        return PyErr_WarnEx(NULL, message, 1);
    }
    return 0;
}

/* VoidPtrImport */
#ifndef __PYX_HAVE_RT_ImportVoidPtr
#define __PYX_HAVE_RT_ImportVoidPtr
static int __Pyx_ImportVoidPtr(PyObject *module, const char *name, void **p, const char *sig) {
    PyObject *d = 0;
    PyObject *cobj = 0;
    d = PyObject_GetAttrString(module, (char *)"__pyx_capi__");
    if (!d)
        goto bad;
    cobj = PyDict_GetItemString(d, name);
    if (!cobj) {
        PyErr_Format(PyExc_ImportError,
            "%.200s does not export expected C variable %.200s",
                PyModule_GetName(module), name);
        goto bad;
    }
#if PY_VERSION_HEX >= 0x02070000
    if (!PyCapsule_IsValid(cobj, sig)) {
        PyErr_Format(PyExc_TypeError,
            "C variable %.200s.%.200s has wrong signature (expected %.500s, got %.500s)",
             PyModule_GetName(module), name, sig, PyCapsule_GetName(cobj));
        goto bad;
    }
    *p = PyCapsule_GetPointer(cobj, sig);
#else
    {const char *desc, *s1, *s2;
    desc = (const char *)PyCObject_GetDesc(cobj);
    if (!desc)
        goto bad;
    s1 = desc; s2 = sig;
    while (*s1 != '\0' && *s1 == *s2) { s1++; s2++; }
    if (*s1 != *s2) {
        PyErr_Format(PyExc_TypeError,
            "C variable %.200s.%.200s has wrong signature (expected %.500s, got %.500s)",
             PyModule_GetName(module), name, sig, desc);
        goto bad;
    }
    *p = PyCObject_AsVoidPtr(cobj);}
#endif
    if (!(*p))
        goto bad;
    Py_DECREF(d);
    return 0;
bad:
    Py_XDECREF(d);
    return -1;
}
#endif

/* InitStrings */
static int __Pyx_InitStrings(__Pyx_StringTabEntry *t) {
    while (t->p) {
        #if PY_MAJOR_VERSION < 3
        if (t->is_unicode) {
            *t->p = PyUnicode_DecodeUTF8(t->s, t->n - 1, NULL);
        } else if (t->intern) {
            *t->p = PyString_InternFromString(t->s);
        } else {
            *t->p = PyString_FromStringAndSize(t->s, t->n - 1);
        }
        #else
        if (t->is_unicode | t->is_str) {
            if (t->intern) {
                *t->p = PyUnicode_InternFromString(t->s);
            } else if (t->encoding) {
                *t->p = PyUnicode_Decode(t->s, t->n - 1, t->encoding, NULL);
            } else {
                *t->p = PyUnicode_FromStringAndSize(t->s, t->n - 1);
            }
        } else {
            *t->p = PyBytes_FromStringAndSize(t->s, t->n - 1);
        }
        #endif
        if (!*t->p)
            return -1;
        if (PyObject_Hash(*t->p) == -1)
            return -1;
        ++t;
    }
    return 0;
}

static CYTHON_INLINE PyObject* __Pyx_PyUnicode_FromString(const char* c_str) {
    return __Pyx_PyUnicode_FromStringAndSize(c_str, (Py_ssize_t)strlen(c_str));
}
static CYTHON_INLINE const char* __Pyx_PyObject_AsString(PyObject* o) {
    Py_ssize_t ignore;
    return __Pyx_PyObject_AsStringAndSize(o, &ignore);
}
#if __PYX_DEFAULT_STRING_ENCODING_IS_ASCII || __PYX_DEFAULT_STRING_ENCODING_IS_DEFAULT
#if !CYTHON_PEP393_ENABLED
static const char* __Pyx_PyUnicode_AsStringAndSize(PyObject* o, Py_ssize_t *length) {
    char* defenc_c;
    PyObject* defenc = _PyUnicode_AsDefaultEncodedString(o, NULL);
    if (!defenc) return NULL;
    defenc_c = PyBytes_AS_STRING(defenc);
#if __PYX_DEFAULT_STRING_ENCODING_IS_ASCII
    {
        char* end = defenc_c + PyBytes_GET_SIZE(defenc);
        char* c;
        for (c = defenc_c; c < end; c++) {
            if ((unsigned char) (*c) >= 128) {
                PyUnicode_AsASCIIString(o);
                return NULL;
            }
        }
    }
#endif
    *length = PyBytes_GET_SIZE(defenc);
    return defenc_c;
}
#else
static CYTHON_INLINE const char* __Pyx_PyUnicode_AsStringAndSize(PyObject* o, Py_ssize_t *length) {
    if (unlikely(__Pyx_PyUnicode_READY(o) == -1)) return NULL;
#if __PYX_DEFAULT_STRING_ENCODING_IS_ASCII
    if (likely(PyUnicode_IS_ASCII(o))) {
        *length = PyUnicode_GET_LENGTH(o);
        return PyUnicode_AsUTF8(o);
    } else {
        PyUnicode_AsASCIIString(o);
        return NULL;
    }
#else
    return PyUnicode_AsUTF8AndSize(o, length);
#endif
}
#endif
#endif
static CYTHON_INLINE const char* __Pyx_PyObject_AsStringAndSize(PyObject* o, Py_ssize_t *length) {
#if __PYX_DEFAULT_STRING_ENCODING_IS_ASCII || __PYX_DEFAULT_STRING_ENCODING_IS_DEFAULT
    if (
#if PY_MAJOR_VERSION < 3 && __PYX_DEFAULT_STRING_ENCODING_IS_ASCII
            __Pyx_sys_getdefaultencoding_not_ascii &&
#endif
            PyUnicode_Check(o)) {
        return __Pyx_PyUnicode_AsStringAndSize(o, length);
    } else
#endif
#if (!CYTHON_COMPILING_IN_PYPY) || (defined(PyByteArray_AS_STRING) && defined(PyByteArray_GET_SIZE))
    if (PyByteArray_Check(o)) {
        *length = PyByteArray_GET_SIZE(o);
        return PyByteArray_AS_STRING(o);
    } else
#endif
    {
        char* result;
        int r = PyBytes_AsStringAndSize(o, &result, length);
        if (unlikely(r < 0)) {
            return NULL;
        } else {
            return result;
        }
    }
}
static CYTHON_INLINE int __Pyx_PyObject_IsTrue(PyObject* x) {
   int is_true = x == Py_True;
   if (is_true | (x == Py_False) | (x == Py_None)) return is_true;
   else return PyObject_IsTrue(x);
}
static CYTHON_INLINE int __Pyx_PyObject_IsTrueAndDecref(PyObject* x) {
    int retval;
    if (unlikely(!x)) return -1;
    retval = __Pyx_PyObject_IsTrue(x);
    Py_DECREF(x);
    return retval;
}
static PyObject* __Pyx_PyNumber_IntOrLongWrongResultType(PyObject* result, const char* type_name) {
#if PY_MAJOR_VERSION >= 3
    if (PyLong_Check(result)) {
        if (PyErr_WarnFormat(PyExc_DeprecationWarning, 1,
                "__int__ returned non-int (type %.200s).  "
                "The ability to return an instance of a strict subclass of int "
                "is deprecated, and may be removed in a future version of Python.",
                Py_TYPE(result)->tp_name)) {
            Py_DECREF(result);
            return NULL;
        }
        return result;
    }
#endif
    PyErr_Format(PyExc_TypeError,
                 "__%.4s__ returned non-%.4s (type %.200s)",
                 type_name, type_name, Py_TYPE(result)->tp_name);
    Py_DECREF(result);
    return NULL;
}
static CYTHON_INLINE PyObject* __Pyx_PyNumber_IntOrLong(PyObject* x) {
#if CYTHON_USE_TYPE_SLOTS
  PyNumberMethods *m;
#endif
  const char *name = NULL;
  PyObject *res = NULL;
#if PY_MAJOR_VERSION < 3
  if (likely(PyInt_Check(x) || PyLong_Check(x)))
#else
  if (likely(PyLong_Check(x)))
#endif
    return __Pyx_NewRef(x);
#if CYTHON_USE_TYPE_SLOTS
  m = Py_TYPE(x)->tp_as_number;
  #if PY_MAJOR_VERSION < 3
  if (m && m->nb_int) {
    name = "int";
    res = m->nb_int(x);
  }
  else if (m && m->nb_long) {
    name = "long";
    res = m->nb_long(x);
  }
  #else
  if (likely(m && m->nb_int)) {
    name = "int";
    res = m->nb_int(x);
  }
  #endif
#else
  if (!PyBytes_CheckExact(x) && !PyUnicode_CheckExact(x)) {
    res = PyNumber_Int(x);
  }
#endif
  if (likely(res)) {
#if PY_MAJOR_VERSION < 3
    if (unlikely(!PyInt_Check(res) && !PyLong_Check(res))) {
#else
    if (unlikely(!PyLong_CheckExact(res))) {
#endif
        return __Pyx_PyNumber_IntOrLongWrongResultType(res, name);
    }
  }
  else if (!PyErr_Occurred()) {
    PyErr_SetString(PyExc_TypeError,
                    "an integer is required");
  }
  return res;
}
static CYTHON_INLINE Py_ssize_t __Pyx_PyIndex_AsSsize_t(PyObject* b) {
  Py_ssize_t ival;
  PyObject *x;
#if PY_MAJOR_VERSION < 3
  if (likely(PyInt_CheckExact(b))) {
    if (sizeof(Py_ssize_t) >= sizeof(long))
        return PyInt_AS_LONG(b);
    else
        return PyInt_AsSsize_t(b);
  }
#endif
  if (likely(PyLong_CheckExact(b))) {
    #if CYTHON_USE_PYLONG_INTERNALS
    const digit* digits = ((PyLongObject*)b)->ob_digit;
    const Py_ssize_t size = Py_SIZE(b);
    if (likely(__Pyx_sst_abs(size) <= 1)) {
        ival = likely(size) ? digits[0] : 0;
        if (size == -1) ival = -ival;
        return ival;
    } else {
      switch (size) {
         case 2:
           if (8 * sizeof(Py_ssize_t) > 2 * PyLong_SHIFT) {
             return (Py_ssize_t) (((((size_t)digits[1]) << PyLong_SHIFT) | (size_t)digits[0]));
           }
           break;
         case -2:
           if (8 * sizeof(Py_ssize_t) > 2 * PyLong_SHIFT) {
             return -(Py_ssize_t) (((((size_t)digits[1]) << PyLong_SHIFT) | (size_t)digits[0]));
           }
           break;
         case 3:
           if (8 * sizeof(Py_ssize_t) > 3 * PyLong_SHIFT) {
             return (Py_ssize_t) (((((((size_t)digits[2]) << PyLong_SHIFT) | (size_t)digits[1]) << PyLong_SHIFT) | (size_t)digits[0]));
           }
           break;
         case -3:
           if (8 * sizeof(Py_ssize_t) > 3 * PyLong_SHIFT) {
             return -(Py_ssize_t) (((((((size_t)digits[2]) << PyLong_SHIFT) | (size_t)digits[1]) << PyLong_SHIFT) | (size_t)digits[0]));
           }
           break;
         case 4:
           if (8 * sizeof(Py_ssize_t) > 4 * PyLong_SHIFT) {
             return (Py_ssize_t) (((((((((size_t)digits[3]) << PyLong_SHIFT) | (size_t)digits[2]) << PyLong_SHIFT) | (size_t)digits[1]) << PyLong_SHIFT) | (size_t)digits[0]));
           }
           break;
         case -4:
           if (8 * sizeof(Py_ssize_t) > 4 * PyLong_SHIFT) {
             return -(Py_ssize_t) (((((((((size_t)digits[3]) << PyLong_SHIFT) | (size_t)digits[2]) << PyLong_SHIFT) | (size_t)digits[1]) << PyLong_SHIFT) | (size_t)digits[0]));
           }
           break;
      }
    }
    #endif
    return PyLong_AsSsize_t(b);
  }
  x = PyNumber_Index(b);
  if (!x) return -1;
  ival = PyInt_AsSsize_t(x);
  Py_DECREF(x);
  return ival;
}
static CYTHON_INLINE PyObject * __Pyx_PyBool_FromLong(long b) {
  return b ? __Pyx_NewRef(Py_True) : __Pyx_NewRef(Py_False);
}
static CYTHON_INLINE PyObject * __Pyx_PyInt_FromSize_t(size_t ival) {
    return PyInt_FromSize_t(ival);
}


#endif /* Py_PYTHON_H */
