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/* BEGIN: Cython Metadata
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#if CYTHON_ASSUME_SAFE_MACROS
  #define __Pyx_PySequence_SIZE(seq)  Py_SIZE(seq)
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#if PY_MAJOR_VERSION >= 3
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  #define PyInt_Type                   PyLong_Type
  #define PyInt_Check(op)              PyLong_Check(op)
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  #define PyInt_FromString             PyLong_FromString
  #define PyInt_FromUnicode            PyLong_FromUnicode
  #define PyInt_FromLong               PyLong_FromLong
  #define PyInt_FromSize_t             PyLong_FromSize_t
  #define PyInt_FromSsize_t            PyLong_FromSsize_t
  #define PyInt_AsLong                 PyLong_AsLong
  #define PyInt_AS_LONG                PyLong_AS_LONG
  #define PyInt_AsSsize_t              PyLong_AsSsize_t
  #define PyInt_AsUnsignedLongMask     PyLong_AsUnsignedLongMask
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#if PY_MAJOR_VERSION >= 3
  #define PyBoolObject                 PyLongObject
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#if PY_MAJOR_VERSION >= 3 && CYTHON_COMPILING_IN_PYPY
  #ifndef PyUnicode_InternFromString
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#if PY_VERSION_HEX < 0x030200A4
  typedef long Py_hash_t;
  #define __Pyx_PyInt_FromHash_t PyInt_FromLong
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#if PY_MAJOR_VERSION >= 3
  #define __Pyx_PyMethod_New(func, self, klass) ((self) ? PyMethod_New(func, self) : (Py_INCREF(func), func))
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#if CYTHON_USE_ASYNC_SLOTS
  #if PY_VERSION_HEX >= 0x030500B1
    #define __Pyx_PyAsyncMethodsStruct PyAsyncMethods
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#else
  #define __Pyx_PyType_AsAsync(obj) NULL
#endif
#ifndef __Pyx_PyAsyncMethodsStruct
    typedef struct {
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    } __Pyx_PyAsyncMethodsStruct;
#endif

#if defined(WIN32) || defined(MS_WINDOWS)
  #define _USE_MATH_DEFINES
#endif
#include <math.h>
#ifdef NAN
#define __PYX_NAN() ((float) NAN)
#else
static CYTHON_INLINE float __PYX_NAN() {
  float value;
  memset(&value, 0xFF, sizeof(value));
  return value;
}
#endif
#if defined(__CYGWIN__) && defined(_LDBL_EQ_DBL)
#define __Pyx_truncl trunc
#else
#define __Pyx_truncl truncl
#endif


#define __PYX_ERR(f_index, lineno, Ln_error) \
{ \
  __pyx_filename = __pyx_f[f_index]; __pyx_lineno = lineno; __pyx_clineno = __LINE__; goto Ln_error; \
}

#ifndef __PYX_EXTERN_C
  #ifdef __cplusplus
    #define __PYX_EXTERN_C extern "C"
  #else
    #define __PYX_EXTERN_C extern
  #endif
#endif

#define __PYX_HAVE__ms_deisotope___c__similarity_methods
#define __PYX_HAVE_API__ms_deisotope___c__similarity_methods
/* Early includes */
#include <math.h>
#include <string.h>
#include <stdlib.h>
#include <stdio.h>
#include "pythread.h"
#include "numpy/arrayobject.h"
#include "numpy/ufuncobject.h"
#ifdef _OPENMP
#include <omp.h>
#endif /* _OPENMP */

#if defined(PYREX_WITHOUT_ASSERTIONS) && !defined(CYTHON_WITHOUT_ASSERTIONS)
#define CYTHON_WITHOUT_ASSERTIONS
#endif

typedef struct {PyObject **p; const char *s; const Py_ssize_t n; const char* encoding;
                const char is_unicode; const char is_str; const char intern; } __Pyx_StringTabEntry;

#define __PYX_DEFAULT_STRING_ENCODING_IS_ASCII 0
#define __PYX_DEFAULT_STRING_ENCODING_IS_UTF8 0
#define __PYX_DEFAULT_STRING_ENCODING_IS_DEFAULT (PY_MAJOR_VERSION >= 3 && __PYX_DEFAULT_STRING_ENCODING_IS_UTF8)
#define __PYX_DEFAULT_STRING_ENCODING ""
#define __Pyx_PyObject_FromString __Pyx_PyBytes_FromString
#define __Pyx_PyObject_FromStringAndSize __Pyx_PyBytes_FromStringAndSize
#define __Pyx_uchar_cast(c) ((unsigned char)c)
#define __Pyx_long_cast(x) ((long)x)
#define __Pyx_fits_Py_ssize_t(v, type, is_signed)  (\
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    (sizeof(type) > sizeof(Py_ssize_t) &&\
          likely(v < (type)PY_SSIZE_T_MAX ||\
                 v == (type)PY_SSIZE_T_MAX)  &&\
          (!is_signed || likely(v > (type)PY_SSIZE_T_MIN ||\
                                v == (type)PY_SSIZE_T_MIN)))  ||\
    (sizeof(type) == sizeof(Py_ssize_t) &&\
          (is_signed || likely(v < (type)PY_SSIZE_T_MAX ||\
                               v == (type)PY_SSIZE_T_MAX)))  )
static CYTHON_INLINE int __Pyx_is_valid_index(Py_ssize_t i, Py_ssize_t limit) {
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}
#if defined (__cplusplus) && __cplusplus >= 201103L
    #include <cstdlib>
    #define __Pyx_sst_abs(value) std::abs(value)
#elif SIZEOF_INT >= SIZEOF_SIZE_T
    #define __Pyx_sst_abs(value) abs(value)
#elif SIZEOF_LONG >= SIZEOF_SIZE_T
    #define __Pyx_sst_abs(value) labs(value)
#elif defined (_MSC_VER)
    #define __Pyx_sst_abs(value) ((Py_ssize_t)_abs64(value))
#elif defined (__STDC_VERSION__) && __STDC_VERSION__ >= 199901L
    #define __Pyx_sst_abs(value) llabs(value)
#elif defined (__GNUC__)
    #define __Pyx_sst_abs(value) __builtin_llabs(value)
#else
    #define __Pyx_sst_abs(value) ((value<0) ? -value : value)
#endif
static CYTHON_INLINE const char* __Pyx_PyObject_AsString(PyObject*);
static CYTHON_INLINE const char* __Pyx_PyObject_AsStringAndSize(PyObject*, Py_ssize_t* length);
#define __Pyx_PyByteArray_FromString(s) PyByteArray_FromStringAndSize((const char*)s, strlen((const char*)s))
#define __Pyx_PyByteArray_FromStringAndSize(s, l) PyByteArray_FromStringAndSize((const char*)s, l)
#define __Pyx_PyBytes_FromString        PyBytes_FromString
#define __Pyx_PyBytes_FromStringAndSize PyBytes_FromStringAndSize
static CYTHON_INLINE PyObject* __Pyx_PyUnicode_FromString(const char*);
#if PY_MAJOR_VERSION < 3
    #define __Pyx_PyStr_FromString        __Pyx_PyBytes_FromString
    #define __Pyx_PyStr_FromStringAndSize __Pyx_PyBytes_FromStringAndSize
#else
    #define __Pyx_PyStr_FromString        __Pyx_PyUnicode_FromString
    #define __Pyx_PyStr_FromStringAndSize __Pyx_PyUnicode_FromStringAndSize
#endif
#define __Pyx_PyBytes_AsWritableString(s)     ((char*) PyBytes_AS_STRING(s))
#define __Pyx_PyBytes_AsWritableSString(s)    ((signed char*) PyBytes_AS_STRING(s))
#define __Pyx_PyBytes_AsWritableUString(s)    ((unsigned char*) PyBytes_AS_STRING(s))
#define __Pyx_PyBytes_AsString(s)     ((const char*) PyBytes_AS_STRING(s))
#define __Pyx_PyBytes_AsSString(s)    ((const signed char*) PyBytes_AS_STRING(s))
#define __Pyx_PyBytes_AsUString(s)    ((const unsigned char*) PyBytes_AS_STRING(s))
#define __Pyx_PyObject_AsWritableString(s)    ((char*) __Pyx_PyObject_AsString(s))
#define __Pyx_PyObject_AsWritableSString(s)    ((signed char*) __Pyx_PyObject_AsString(s))
#define __Pyx_PyObject_AsWritableUString(s)    ((unsigned char*) __Pyx_PyObject_AsString(s))
#define __Pyx_PyObject_AsSString(s)    ((const signed char*) __Pyx_PyObject_AsString(s))
#define __Pyx_PyObject_AsUString(s)    ((const unsigned char*) __Pyx_PyObject_AsString(s))
#define __Pyx_PyObject_FromCString(s)  __Pyx_PyObject_FromString((const char*)s)
#define __Pyx_PyBytes_FromCString(s)   __Pyx_PyBytes_FromString((const char*)s)
#define __Pyx_PyByteArray_FromCString(s)   __Pyx_PyByteArray_FromString((const char*)s)
#define __Pyx_PyStr_FromCString(s)     __Pyx_PyStr_FromString((const char*)s)
#define __Pyx_PyUnicode_FromCString(s) __Pyx_PyUnicode_FromString((const char*)s)
static CYTHON_INLINE size_t __Pyx_Py_UNICODE_strlen(const Py_UNICODE *u) {
    const Py_UNICODE *u_end = u;
    while (*u_end++) ;
    return (size_t)(u_end - u - 1);
}
#define __Pyx_PyUnicode_FromUnicode(u)       PyUnicode_FromUnicode(u, __Pyx_Py_UNICODE_strlen(u))
#define __Pyx_PyUnicode_FromUnicodeAndLength PyUnicode_FromUnicode
#define __Pyx_PyUnicode_AsUnicode            PyUnicode_AsUnicode
#define __Pyx_NewRef(obj) (Py_INCREF(obj), obj)
#define __Pyx_Owned_Py_None(b) __Pyx_NewRef(Py_None)
static CYTHON_INLINE PyObject * __Pyx_PyBool_FromLong(long b);
static CYTHON_INLINE int __Pyx_PyObject_IsTrue(PyObject*);
static CYTHON_INLINE int __Pyx_PyObject_IsTrueAndDecref(PyObject*);
static CYTHON_INLINE PyObject* __Pyx_PyNumber_IntOrLong(PyObject* x);
#define __Pyx_PySequence_Tuple(obj)\
    (likely(PyTuple_CheckExact(obj)) ? __Pyx_NewRef(obj) : PySequence_Tuple(obj))
static CYTHON_INLINE Py_ssize_t __Pyx_PyIndex_AsSsize_t(PyObject*);
static CYTHON_INLINE PyObject * __Pyx_PyInt_FromSize_t(size_t);
#if CYTHON_ASSUME_SAFE_MACROS
#define __pyx_PyFloat_AsDouble(x) (PyFloat_CheckExact(x) ? PyFloat_AS_DOUBLE(x) : PyFloat_AsDouble(x))
#else
#define __pyx_PyFloat_AsDouble(x) PyFloat_AsDouble(x)
#endif
#define __pyx_PyFloat_AsFloat(x) ((float) __pyx_PyFloat_AsDouble(x))
#if PY_MAJOR_VERSION >= 3
#define __Pyx_PyNumber_Int(x) (PyLong_CheckExact(x) ? __Pyx_NewRef(x) : PyNumber_Long(x))
#else
#define __Pyx_PyNumber_Int(x) (PyInt_CheckExact(x) ? __Pyx_NewRef(x) : PyNumber_Int(x))
#endif
#define __Pyx_PyNumber_Float(x) (PyFloat_CheckExact(x) ? __Pyx_NewRef(x) : PyNumber_Float(x))
#if PY_MAJOR_VERSION < 3 && __PYX_DEFAULT_STRING_ENCODING_IS_ASCII
static int __Pyx_sys_getdefaultencoding_not_ascii;
static int __Pyx_init_sys_getdefaultencoding_params(void) {
    PyObject* sys;
    PyObject* default_encoding = NULL;
    PyObject* ascii_chars_u = NULL;
    PyObject* ascii_chars_b = NULL;
    const char* default_encoding_c;
    sys = PyImport_ImportModule("sys");
    if (!sys) goto bad;
    default_encoding = PyObject_CallMethod(sys, (char*) "getdefaultencoding", NULL);
    Py_DECREF(sys);
    if (!default_encoding) goto bad;
    default_encoding_c = PyBytes_AsString(default_encoding);
    if (!default_encoding_c) goto bad;
    if (strcmp(default_encoding_c, "ascii") == 0) {
        __Pyx_sys_getdefaultencoding_not_ascii = 0;
    } else {
        char ascii_chars[128];
        int c;
        for (c = 0; c < 128; c++) {
            ascii_chars[c] = c;
        }
        __Pyx_sys_getdefaultencoding_not_ascii = 1;
        ascii_chars_u = PyUnicode_DecodeASCII(ascii_chars, 128, NULL);
        if (!ascii_chars_u) goto bad;
        ascii_chars_b = PyUnicode_AsEncodedString(ascii_chars_u, default_encoding_c, NULL);
        if (!ascii_chars_b || !PyBytes_Check(ascii_chars_b) || memcmp(ascii_chars, PyBytes_AS_STRING(ascii_chars_b), 128) != 0) {
            PyErr_Format(
                PyExc_ValueError,
                "This module compiled with c_string_encoding=ascii, but default encoding '%.200s' is not a superset of ascii.",
                default_encoding_c);
            goto bad;
        }
        Py_DECREF(ascii_chars_u);
        Py_DECREF(ascii_chars_b);
    }
    Py_DECREF(default_encoding);
    return 0;
bad:
    Py_XDECREF(default_encoding);
    Py_XDECREF(ascii_chars_u);
    Py_XDECREF(ascii_chars_b);
    return -1;
}
#endif
#if __PYX_DEFAULT_STRING_ENCODING_IS_DEFAULT && PY_MAJOR_VERSION >= 3
#define __Pyx_PyUnicode_FromStringAndSize(c_str, size) PyUnicode_DecodeUTF8(c_str, size, NULL)
#else
#define __Pyx_PyUnicode_FromStringAndSize(c_str, size) PyUnicode_Decode(c_str, size, __PYX_DEFAULT_STRING_ENCODING, NULL)
#if __PYX_DEFAULT_STRING_ENCODING_IS_DEFAULT
static char* __PYX_DEFAULT_STRING_ENCODING;
static int __Pyx_init_sys_getdefaultencoding_params(void) {
    PyObject* sys;
    PyObject* default_encoding = NULL;
    char* default_encoding_c;
    sys = PyImport_ImportModule("sys");
    if (!sys) goto bad;
    default_encoding = PyObject_CallMethod(sys, (char*) (const char*) "getdefaultencoding", NULL);
    Py_DECREF(sys);
    if (!default_encoding) goto bad;
    default_encoding_c = PyBytes_AsString(default_encoding);
    if (!default_encoding_c) goto bad;
    __PYX_DEFAULT_STRING_ENCODING = (char*) malloc(strlen(default_encoding_c) + 1);
    if (!__PYX_DEFAULT_STRING_ENCODING) goto bad;
    strcpy(__PYX_DEFAULT_STRING_ENCODING, default_encoding_c);
    Py_DECREF(default_encoding);
    return 0;
bad:
    Py_XDECREF(default_encoding);
    return -1;
}
#endif
#endif


/* Test for GCC > 2.95 */
#if defined(__GNUC__)     && (__GNUC__ > 2 || (__GNUC__ == 2 && (__GNUC_MINOR__ > 95)))
  #define likely(x)   __builtin_expect(!!(x), 1)
  #define unlikely(x) __builtin_expect(!!(x), 0)
#else /* !__GNUC__ or GCC < 2.95 */
  #define likely(x)   (x)
  #define unlikely(x) (x)
#endif /* __GNUC__ */
static CYTHON_INLINE void __Pyx_pretend_to_initialize(void* ptr) { (void)ptr; }

static PyObject *__pyx_m = NULL;
static PyObject *__pyx_d;
static PyObject *__pyx_b;
static PyObject *__pyx_cython_runtime = NULL;
static PyObject *__pyx_empty_tuple;
static PyObject *__pyx_empty_bytes;
static PyObject *__pyx_empty_unicode;
static int __pyx_lineno;
static int __pyx_clineno = 0;
static const char * __pyx_cfilenm= __FILE__;
static const char *__pyx_filename;

/* Header.proto */
#if !defined(CYTHON_CCOMPLEX)
  #if defined(__cplusplus)
    #define CYTHON_CCOMPLEX 1
  #elif defined(_Complex_I)
    #define CYTHON_CCOMPLEX 1
  #else
    #define CYTHON_CCOMPLEX 0
  #endif
#endif
#if CYTHON_CCOMPLEX
  #ifdef __cplusplus
    #include <complex>
  #else
    #include <complex.h>
  #endif
#endif
#if CYTHON_CCOMPLEX && !defined(__cplusplus) && defined(__sun__) && defined(__GNUC__)
  #undef _Complex_I
  #define _Complex_I 1.0fj
#endif


static const char *__pyx_f[] = {
  "ms_deisotope\\_c\\similarity_methods.pyx",
  "stringsource",
  "__init__.pxd",
  "type.pxd",
  "bool.pxd",
  "complex.pxd",
  "peak_set.pxd",
  "peak_index.pxd",
  "composition.pxd",
  "isotopic_distribution.pxd",
  "ms_deisotope\\_c\\averagine.pxd",
  "ms_deisotope\\_c\\deconvoluter_base.pxd",
  "ms_deisotope\\_c\\scoring.pxd",
  "ms_deisotope\\_c\\peak_set.pxd",
};
/* NoFastGil.proto */
#define __Pyx_PyGILState_Ensure PyGILState_Ensure
#define __Pyx_PyGILState_Release PyGILState_Release
#define __Pyx_FastGIL_Remember()
#define __Pyx_FastGIL_Forget()
#define __Pyx_FastGilFuncInit()

/* BufferFormatStructs.proto */
#define IS_UNSIGNED(type) (((type) -1) > 0)
struct __Pyx_StructField_;
#define __PYX_BUF_FLAGS_PACKED_STRUCT (1 << 0)
typedef struct {
  const char* name;
  struct __Pyx_StructField_* fields;
  size_t size;
  size_t arraysize[8];
  int ndim;
  char typegroup;
  char is_unsigned;
  int flags;
} __Pyx_TypeInfo;
typedef struct __Pyx_StructField_ {
  __Pyx_TypeInfo* type;
  const char* name;
  size_t offset;
} __Pyx_StructField;
typedef struct {
  __Pyx_StructField* field;
  size_t parent_offset;
} __Pyx_BufFmt_StackElem;
typedef struct {
  __Pyx_StructField root;
  __Pyx_BufFmt_StackElem* head;
  size_t fmt_offset;
  size_t new_count, enc_count;
  size_t struct_alignment;
  int is_complex;
  char enc_type;
  char new_packmode;
  char enc_packmode;
  char is_valid_array;
} __Pyx_BufFmt_Context;

/* ForceInitThreads.proto */
#ifndef __PYX_FORCE_INIT_THREADS
  #define __PYX_FORCE_INIT_THREADS 0
#endif


/* "C:/hostedtoolcache/windows/Python/3.7.6/x64/lib/site-packages/Cython/Includes/numpy/__init__.pxd":776
 * # in Cython to enable them only on the right systems.
 * 
 * ctypedef npy_int8       int8_t             # <<<<<<<<<<<<<<
 * ctypedef npy_int16      int16_t
 * ctypedef npy_int32      int32_t
 */
typedef npy_int8 __pyx_t_5numpy_int8_t;

/* "C:/hostedtoolcache/windows/Python/3.7.6/x64/lib/site-packages/Cython/Includes/numpy/__init__.pxd":777
 * 
 * ctypedef npy_int8       int8_t
 * ctypedef npy_int16      int16_t             # <<<<<<<<<<<<<<
 * ctypedef npy_int32      int32_t
 * ctypedef npy_int64      int64_t
 */
typedef npy_int16 __pyx_t_5numpy_int16_t;

/* "C:/hostedtoolcache/windows/Python/3.7.6/x64/lib/site-packages/Cython/Includes/numpy/__init__.pxd":778
 * ctypedef npy_int8       int8_t
 * ctypedef npy_int16      int16_t
 * ctypedef npy_int32      int32_t             # <<<<<<<<<<<<<<
 * ctypedef npy_int64      int64_t
 * #ctypedef npy_int96      int96_t
 */
typedef npy_int32 __pyx_t_5numpy_int32_t;

/* "C:/hostedtoolcache/windows/Python/3.7.6/x64/lib/site-packages/Cython/Includes/numpy/__init__.pxd":779
 * ctypedef npy_int16      int16_t
 * ctypedef npy_int32      int32_t
 * ctypedef npy_int64      int64_t             # <<<<<<<<<<<<<<
 * #ctypedef npy_int96      int96_t
 * #ctypedef npy_int128     int128_t
 */
typedef npy_int64 __pyx_t_5numpy_int64_t;

/* "C:/hostedtoolcache/windows/Python/3.7.6/x64/lib/site-packages/Cython/Includes/numpy/__init__.pxd":783
 * #ctypedef npy_int128     int128_t
 * 
 * ctypedef npy_uint8      uint8_t             # <<<<<<<<<<<<<<
 * ctypedef npy_uint16     uint16_t
 * ctypedef npy_uint32     uint32_t
 */
typedef npy_uint8 __pyx_t_5numpy_uint8_t;

/* "C:/hostedtoolcache/windows/Python/3.7.6/x64/lib/site-packages/Cython/Includes/numpy/__init__.pxd":784
 * 
 * ctypedef npy_uint8      uint8_t
 * ctypedef npy_uint16     uint16_t             # <<<<<<<<<<<<<<
 * ctypedef npy_uint32     uint32_t
 * ctypedef npy_uint64     uint64_t
 */
typedef npy_uint16 __pyx_t_5numpy_uint16_t;

/* "C:/hostedtoolcache/windows/Python/3.7.6/x64/lib/site-packages/Cython/Includes/numpy/__init__.pxd":785
 * ctypedef npy_uint8      uint8_t
 * ctypedef npy_uint16     uint16_t
 * ctypedef npy_uint32     uint32_t             # <<<<<<<<<<<<<<
 * ctypedef npy_uint64     uint64_t
 * #ctypedef npy_uint96     uint96_t
 */
typedef npy_uint32 __pyx_t_5numpy_uint32_t;

/* "C:/hostedtoolcache/windows/Python/3.7.6/x64/lib/site-packages/Cython/Includes/numpy/__init__.pxd":786
 * ctypedef npy_uint16     uint16_t
 * ctypedef npy_uint32     uint32_t
 * ctypedef npy_uint64     uint64_t             # <<<<<<<<<<<<<<
 * #ctypedef npy_uint96     uint96_t
 * #ctypedef npy_uint128    uint128_t
 */
typedef npy_uint64 __pyx_t_5numpy_uint64_t;

/* "C:/hostedtoolcache/windows/Python/3.7.6/x64/lib/site-packages/Cython/Includes/numpy/__init__.pxd":790
 * #ctypedef npy_uint128    uint128_t
 * 
 * ctypedef npy_float32    float32_t             # <<<<<<<<<<<<<<
 * ctypedef npy_float64    float64_t
 * #ctypedef npy_float80    float80_t
 */
typedef npy_float32 __pyx_t_5numpy_float32_t;

/* "C:/hostedtoolcache/windows/Python/3.7.6/x64/lib/site-packages/Cython/Includes/numpy/__init__.pxd":791
 * 
 * ctypedef npy_float32    float32_t
 * ctypedef npy_float64    float64_t             # <<<<<<<<<<<<<<
 * #ctypedef npy_float80    float80_t
 * #ctypedef npy_float128   float128_t
 */
typedef npy_float64 __pyx_t_5numpy_float64_t;

/* "C:/hostedtoolcache/windows/Python/3.7.6/x64/lib/site-packages/Cython/Includes/numpy/__init__.pxd":800
 * # The int types are mapped a bit surprising --
 * # numpy.int corresponds to 'l' and numpy.long to 'q'
 * ctypedef npy_long       int_t             # <<<<<<<<<<<<<<
 * ctypedef npy_longlong   long_t
 * ctypedef npy_longlong   longlong_t
 */
typedef npy_long __pyx_t_5numpy_int_t;

/* "C:/hostedtoolcache/windows/Python/3.7.6/x64/lib/site-packages/Cython/Includes/numpy/__init__.pxd":801
 * # numpy.int corresponds to 'l' and numpy.long to 'q'
 * ctypedef npy_long       int_t
 * ctypedef npy_longlong   long_t             # <<<<<<<<<<<<<<
 * ctypedef npy_longlong   longlong_t
 * 
 */
typedef npy_longlong __pyx_t_5numpy_long_t;

/* "C:/hostedtoolcache/windows/Python/3.7.6/x64/lib/site-packages/Cython/Includes/numpy/__init__.pxd":802
 * ctypedef npy_long       int_t
 * ctypedef npy_longlong   long_t
 * ctypedef npy_longlong   longlong_t             # <<<<<<<<<<<<<<
 * 
 * ctypedef npy_ulong      uint_t
 */
typedef npy_longlong __pyx_t_5numpy_longlong_t;

/* "C:/hostedtoolcache/windows/Python/3.7.6/x64/lib/site-packages/Cython/Includes/numpy/__init__.pxd":804
 * ctypedef npy_longlong   longlong_t
 * 
 * ctypedef npy_ulong      uint_t             # <<<<<<<<<<<<<<
 * ctypedef npy_ulonglong  ulong_t
 * ctypedef npy_ulonglong  ulonglong_t
 */
typedef npy_ulong __pyx_t_5numpy_uint_t;

/* "C:/hostedtoolcache/windows/Python/3.7.6/x64/lib/site-packages/Cython/Includes/numpy/__init__.pxd":805
 * 
 * ctypedef npy_ulong      uint_t
 * ctypedef npy_ulonglong  ulong_t             # <<<<<<<<<<<<<<
 * ctypedef npy_ulonglong  ulonglong_t
 * 
 */
typedef npy_ulonglong __pyx_t_5numpy_ulong_t;

/* "C:/hostedtoolcache/windows/Python/3.7.6/x64/lib/site-packages/Cython/Includes/numpy/__init__.pxd":806
 * ctypedef npy_ulong      uint_t
 * ctypedef npy_ulonglong  ulong_t
 * ctypedef npy_ulonglong  ulonglong_t             # <<<<<<<<<<<<<<
 * 
 * ctypedef npy_intp       intp_t
 */
typedef npy_ulonglong __pyx_t_5numpy_ulonglong_t;

/* "C:/hostedtoolcache/windows/Python/3.7.6/x64/lib/site-packages/Cython/Includes/numpy/__init__.pxd":808
 * ctypedef npy_ulonglong  ulonglong_t
 * 
 * ctypedef npy_intp       intp_t             # <<<<<<<<<<<<<<
 * ctypedef npy_uintp      uintp_t
 * 
 */
typedef npy_intp __pyx_t_5numpy_intp_t;

/* "C:/hostedtoolcache/windows/Python/3.7.6/x64/lib/site-packages/Cython/Includes/numpy/__init__.pxd":809
 * 
 * ctypedef npy_intp       intp_t
 * ctypedef npy_uintp      uintp_t             # <<<<<<<<<<<<<<
 * 
 * ctypedef npy_double     float_t
 */
typedef npy_uintp __pyx_t_5numpy_uintp_t;

/* "C:/hostedtoolcache/windows/Python/3.7.6/x64/lib/site-packages/Cython/Includes/numpy/__init__.pxd":811
 * ctypedef npy_uintp      uintp_t
 * 
 * ctypedef npy_double     float_t             # <<<<<<<<<<<<<<
 * ctypedef npy_double     double_t
 * ctypedef npy_longdouble longdouble_t
 */
typedef npy_double __pyx_t_5numpy_float_t;

/* "C:/hostedtoolcache/windows/Python/3.7.6/x64/lib/site-packages/Cython/Includes/numpy/__init__.pxd":812
 * 
 * ctypedef npy_double     float_t
 * ctypedef npy_double     double_t             # <<<<<<<<<<<<<<
 * ctypedef npy_longdouble longdouble_t
 * 
 */
typedef npy_double __pyx_t_5numpy_double_t;

/* "C:/hostedtoolcache/windows/Python/3.7.6/x64/lib/site-packages/Cython/Includes/numpy/__init__.pxd":813
 * ctypedef npy_double     float_t
 * ctypedef npy_double     double_t
 * ctypedef npy_longdouble longdouble_t             # <<<<<<<<<<<<<<
 * 
 * ctypedef npy_cfloat      cfloat_t
 */
typedef npy_longdouble __pyx_t_5numpy_longdouble_t;

/* "brainpy/_c/composition.pxd":3
 * from brainpy.mass_dict import nist_mass as __nist_mass
 * 
 * ctypedef long count_type             # <<<<<<<<<<<<<<
 * 
 * cdef dict nist_mass
 */
typedef long __pyx_t_7brainpy_2_c_11composition_count_type;
/* Declarations.proto */
#if CYTHON_CCOMPLEX
  #ifdef __cplusplus
    typedef ::std::complex< float > __pyx_t_float_complex;
  #else
    typedef float _Complex __pyx_t_float_complex;
  #endif
#else
    typedef struct { float real, imag; } __pyx_t_float_complex;
#endif
static CYTHON_INLINE __pyx_t_float_complex __pyx_t_float_complex_from_parts(float, float);

/* Declarations.proto */
#if CYTHON_CCOMPLEX
  #ifdef __cplusplus
    typedef ::std::complex< double > __pyx_t_double_complex;
  #else
    typedef double _Complex __pyx_t_double_complex;
  #endif
#else
    typedef struct { double real, imag; } __pyx_t_double_complex;
#endif
static CYTHON_INLINE __pyx_t_double_complex __pyx_t_double_complex_from_parts(double, double);


/*--- Type declarations ---*/
struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakBase;
struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_FittedPeak;
struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSet;
struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSetIndexed;
struct __pyx_obj_14ms_peak_picker_2_c_10peak_index_PeakIndex;
struct __pyx_obj_7brainpy_2_c_11composition_PyComposition;
struct __pyx_obj_7brainpy_2_c_21isotopic_distribution_TheoreticalPeak;
struct __pyx_obj_12ms_deisotope_2_c_9averagine_Averagine;
struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern;
struct __pyx_obj_12ms_deisotope_2_c_9averagine_AveragineCache;
struct __pyx_obj_12ms_deisotope_2_c_17deconvoluter_base_DeconvoluterBase;
struct __pyx_obj_12ms_deisotope_2_c_17deconvoluter_base_AveragineDeconvoluterBase;
struct __pyx_obj_12ms_deisotope_2_c_17deconvoluter_base_MultiAveragineDeconvoluterBase;
struct __pyx_obj_12ms_deisotope_2_c_17deconvoluter_base_ChargeIterator;
struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitRecord;
struct __pyx_obj_12ms_deisotope_2_c_7scoring_FitSelectorBase;
struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitterBase;
struct __pyx_obj_12ms_deisotope_2_c_7scoring_LeastSquaresFitter;
struct __pyx_obj_12ms_deisotope_2_c_7scoring_GTestFitter;
struct __pyx_obj_12ms_deisotope_2_c_7scoring_ScaledGTestFitter;
struct __pyx_obj_12ms_deisotope_2_c_7scoring_MSDeconVFitter;
struct __pyx_obj_12ms_deisotope_2_c_7scoring_PenalizedMSDeconVFitter;
struct __pyx_obj_12ms_deisotope_2_c_7scoring_FunctionScorer;
struct __pyx_obj_12ms_deisotope_2_c_7scoring_InterferenceDetection;
struct __pyx_obj_12ms_deisotope_2_c_7scoring_DistinctPatternFitter;
struct __pyx_obj_12ms_deisotope_2_c_7scoring_ScaledPenalizedMSDeconvFitter;
struct __pyx_obj_12ms_deisotope_2_c_7scoring_DotProductFitter;
struct __pyx_obj_12ms_deisotope_2_c_8peak_set__Index;
struct __pyx_obj_12ms_deisotope_2_c_8peak_set_EnvelopePair;
struct __pyx_obj_12ms_deisotope_2_c_8peak_set_Envelope;
struct __pyx_obj_12ms_deisotope_2_c_8peak_set_DeconvolutedPeak;
struct __pyx_obj_12ms_deisotope_2_c_8peak_set_DeconvolutedPeakSolution;
struct __pyx_obj_12ms_deisotope_2_c_8peak_set_DeconvolutedPeakSet;
struct __pyx_obj_12ms_deisotope_2_c_8peak_set_DeconvolutedPeakSetIndexed;
struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_PeakMatch;
struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_SpectrumAlignment;
struct __pyx_obj___Pyx_EnumMeta;

/* "C:/hostedtoolcache/windows/Python/3.7.6/x64/lib/site-packages/Cython/Includes/numpy/__init__.pxd":815
 * ctypedef npy_longdouble longdouble_t
 * 
 * ctypedef npy_cfloat      cfloat_t             # <<<<<<<<<<<<<<
 * ctypedef npy_cdouble     cdouble_t
 * ctypedef npy_clongdouble clongdouble_t
 */
typedef npy_cfloat __pyx_t_5numpy_cfloat_t;

/* "C:/hostedtoolcache/windows/Python/3.7.6/x64/lib/site-packages/Cython/Includes/numpy/__init__.pxd":816
 * 
 * ctypedef npy_cfloat      cfloat_t
 * ctypedef npy_cdouble     cdouble_t             # <<<<<<<<<<<<<<
 * ctypedef npy_clongdouble clongdouble_t
 * 
 */
typedef npy_cdouble __pyx_t_5numpy_cdouble_t;

/* "C:/hostedtoolcache/windows/Python/3.7.6/x64/lib/site-packages/Cython/Includes/numpy/__init__.pxd":817
 * ctypedef npy_cfloat      cfloat_t
 * ctypedef npy_cdouble     cdouble_t
 * ctypedef npy_clongdouble clongdouble_t             # <<<<<<<<<<<<<<
 * 
 * ctypedef npy_cdouble     complex_t
 */
typedef npy_clongdouble __pyx_t_5numpy_clongdouble_t;

/* "C:/hostedtoolcache/windows/Python/3.7.6/x64/lib/site-packages/Cython/Includes/numpy/__init__.pxd":819
 * ctypedef npy_clongdouble clongdouble_t
 * 
 * ctypedef npy_cdouble     complex_t             # <<<<<<<<<<<<<<
 * 
 * cdef inline object PyArray_MultiIterNew1(a):
 */
typedef npy_cdouble __pyx_t_5numpy_complex_t;
struct __pyx_opt_args_14ms_peak_picker_2_c_8peak_set_7PeakSet__has_peak;
struct __pyx_opt_args_14ms_peak_picker_2_c_8peak_set_7PeakSet_all_peaks_for;
struct __pyx_t_14ms_peak_picker_2_c_8peak_set_index_cell;
struct __pyx_t_14ms_peak_picker_2_c_8peak_set_index_list;
struct __pyx_opt_args_14ms_peak_picker_2_c_8peak_set_14PeakSetIndexed_has_peak_hinted;

/* "ms_peak_picker/_c/peak_set.pxd":42
 *     cdef FittedPeak _get_nearest_peak(self, double mz, double* errout)
 * 
 *     cdef FittedPeak _has_peak(self, double mz, double tolerance=*)             # <<<<<<<<<<<<<<
 * 
 *     cpdef PeakSet clone(self)
 */
struct __pyx_opt_args_14ms_peak_picker_2_c_8peak_set_7PeakSet__has_peak {
  int __pyx_n;
  double tolerance;
};

/* "ms_peak_picker/_c/peak_set.pxd":50
 *     cdef int _between_bounds(self, double m1, double m2, size_t* startp, size_t* endp)
 * 
 *     cpdef tuple all_peaks_for(self, double mz, double error_tolerance=*)             # <<<<<<<<<<<<<<
 * 
 *     cdef FittedPeak getitem(self, size_t i)
 */
struct __pyx_opt_args_14ms_peak_picker_2_c_8peak_set_7PeakSet_all_peaks_for {
  int __pyx_n;
  double error_tolerance;
};

/* "ms_peak_picker/_c/peak_set.pxd":64
 * 
 * 
 * cdef struct index_cell:             # <<<<<<<<<<<<<<
 *     double center_value
 *     size_t start
 */
struct __pyx_t_14ms_peak_picker_2_c_8peak_set_index_cell {
  double center_value;
  size_t start;
  size_t end;
};

/* "ms_peak_picker/_c/peak_set.pxd":70
 * 
 * 
 * cdef struct index_list:             # <<<<<<<<<<<<<<
 *     index_cell* index
 *     size_t size
 */
struct __pyx_t_14ms_peak_picker_2_c_8peak_set_index_list {
  struct __pyx_t_14ms_peak_picker_2_c_8peak_set_index_cell *index;
  size_t size;
  double low;
  double high;
};

/* "ms_peak_picker/_c/peak_set.pxd":90
 *     cpdef _allocate_index(self, size_t interval_index_size)
 * 
 *     cpdef FittedPeak has_peak_hinted(self, double mz, double tolerance=*, size_t hint_start=*, size_t hint_end=*)             # <<<<<<<<<<<<<<
 * 
 * cdef size_t double_binary_search_ppm(double* array, double value, double tolerance, size_t n)
 */
struct __pyx_opt_args_14ms_peak_picker_2_c_8peak_set_14PeakSetIndexed_has_peak_hinted {
  int __pyx_n;
  double tolerance;
  size_t hint_start;
  size_t hint_end;
};
struct __pyx_opt_args_14ms_peak_picker_2_c_10peak_index_9PeakIndex__has_peak;
struct __pyx_opt_args_14ms_peak_picker_2_c_10peak_index_9PeakIndex_all_peaks_for;

/* "ms_peak_picker/_c/peak_index.pxd":11
 *         public PeakSet peaks
 * 
 *     cdef FittedPeak _has_peak(self, double mz, double tolerance=*)             # <<<<<<<<<<<<<<
 *     cdef PeakSet _between(self, double start, double stop)
 * 
 */
struct __pyx_opt_args_14ms_peak_picker_2_c_10peak_index_9PeakIndex__has_peak {
  int __pyx_n;
  double tolerance;
};

/* "ms_peak_picker/_c/peak_index.pxd":14
 *     cdef PeakSet _between(self, double start, double stop)
 * 
 *     cpdef tuple all_peaks_for(self, double mz, double error_tolerance=*)             # <<<<<<<<<<<<<<
 * 
 *     cdef size_t get_size(self)
 */
struct __pyx_opt_args_14ms_peak_picker_2_c_10peak_index_9PeakIndex_all_peaks_for {
  int __pyx_n;
  double error_tolerance;
};
struct __pyx_opt_args_7brainpy_2_c_11composition_neutral_mass;
struct __pyx_opt_args_7brainpy_2_c_11composition_mass_charge_ratio;
struct __pyx_t_7brainpy_2_c_11composition_Isotope;
struct __pyx_t_7brainpy_2_c_11composition_IsotopeMap;
struct __pyx_t_7brainpy_2_c_11composition_Element;
struct __pyx_t_7brainpy_2_c_11composition_ElementHashBucket;
struct __pyx_t_7brainpy_2_c_11composition_ElementHashTable;
struct __pyx_t_7brainpy_2_c_11composition_Composition;
struct __pyx_opt_args_7brainpy_2_c_11composition_13PyComposition__set_impl;
struct __pyx_opt_args_7brainpy_2_c_11composition_13PyComposition_pop;

/* "brainpy/_c/composition.pxd":10
 * cdef double PROTON = nist_mass["H+"][0][0]
 * 
 * cdef double neutral_mass(double mz,  int z, double charge_carrier=*) nogil             # <<<<<<<<<<<<<<
 * cdef double mass_charge_ratio(double neutral_mass, int z, double charge_carrier=*) nogil
 * cdef char* _parse_isotope_string(char* label, int* isotope_num, char* element_name) nogil
 */
struct __pyx_opt_args_7brainpy_2_c_11composition_neutral_mass {
  int __pyx_n;
  double charge_carrier;
};

/* "brainpy/_c/composition.pxd":11
 * 
 * cdef double neutral_mass(double mz,  int z, double charge_carrier=*) nogil
 * cdef double mass_charge_ratio(double neutral_mass, int z, double charge_carrier=*) nogil             # <<<<<<<<<<<<<<
 * cdef char* _parse_isotope_string(char* label, int* isotope_num, char* element_name) nogil
 * 
 */
struct __pyx_opt_args_7brainpy_2_c_11composition_mass_charge_ratio {
  int __pyx_n;
  double charge_carrier;
};

/* "brainpy/_c/composition.pxd":17
 * # Isotope and IsotopeMap Declarations
 * 
 * cdef struct Isotope:             # <<<<<<<<<<<<<<
 *     double mass
 *     double abundance
 */
struct __pyx_t_7brainpy_2_c_11composition_Isotope {
  double mass;
  double abundance;
  int neutrons;
  int neutron_shift;
};

/* "brainpy/_c/composition.pxd":23
 *     int neutron_shift
 * 
 * cdef struct IsotopeMap:             # <<<<<<<<<<<<<<
 *     Isotope* bins
 *     size_t size
 */
struct __pyx_t_7brainpy_2_c_11composition_IsotopeMap {
  struct __pyx_t_7brainpy_2_c_11composition_Isotope *bins;
  size_t size;
};

/* "brainpy/_c/composition.pxd":36
 * # Element Declarations
 * 
 * cdef struct Element:             # <<<<<<<<<<<<<<
 *     char* symbol
 *     IsotopeMap* isotopes
 */
struct __pyx_t_7brainpy_2_c_11composition_Element {
  char *symbol;
  struct __pyx_t_7brainpy_2_c_11composition_IsotopeMap *isotopes;
  int monoisotopic_isotope_index;
};

/* "brainpy/_c/composition.pxd":56
 * # ElementHashTable and ElementHashBucket Declarations
 * 
 * cdef struct ElementHashBucket:             # <<<<<<<<<<<<<<
 *     Element** elements
 *     size_t used
 */
struct __pyx_t_7brainpy_2_c_11composition_ElementHashBucket {
  struct __pyx_t_7brainpy_2_c_11composition_Element **elements;
  size_t used;
  size_t size;
};

/* "brainpy/_c/composition.pxd":65
 * 
 * 
 * cdef struct ElementHashTable:             # <<<<<<<<<<<<<<
 *     ElementHashBucket* buckets
 *     size_t size
 */
struct __pyx_t_7brainpy_2_c_11composition_ElementHashTable {
  struct __pyx_t_7brainpy_2_c_11composition_ElementHashBucket *buckets;
  size_t size;
};

/* "brainpy/_c/composition.pxd":94
 * # Composition Declarations
 * 
 * cdef struct Composition:             # <<<<<<<<<<<<<<
 *     char** elements
 *     count_type* counts
 */
struct __pyx_t_7brainpy_2_c_11composition_Composition {
  char **elements;
  __pyx_t_7brainpy_2_c_11composition_count_type *counts;
  size_t size;
  size_t used;
  int max_variants;
};

/* "brainpy/_c/composition.pxd":130
 *     @staticmethod
 *     cdef PyComposition _create(Composition* base)
 *     cdef void _set_impl(self, Composition* composition, bint free_existing=*)             # <<<<<<<<<<<<<<
 * 
 *     cdef void _initialize_from_formula(self, str formula)
 */
struct __pyx_opt_args_7brainpy_2_c_11composition_13PyComposition__set_impl {
  int __pyx_n;
  int free_existing;
};

/* "brainpy/_c/composition.pxd":144
 *     cpdef list items(self)
 * 
 *     cpdef pop(self, str key, object default=*)             # <<<<<<<<<<<<<<
 * 
 *     cdef count_type getitem(self, str key)
 */
struct __pyx_opt_args_7brainpy_2_c_11composition_13PyComposition_pop {
  int __pyx_n;
  PyObject *__pyx_default;
};
struct __pyx_t_7brainpy_2_c_13double_vector_DoubleVector;

/* "brainpy/_c/double_vector.pxd":1
 * cdef struct DoubleVector:             # <<<<<<<<<<<<<<
 *     double* v
 *     size_t used
 */
struct __pyx_t_7brainpy_2_c_13double_vector_DoubleVector {
  double *v;
  size_t used;
  size_t size;
};
struct __pyx_t_7brainpy_2_c_18isotopic_constants_PolynomialParameters;
struct __pyx_t_7brainpy_2_c_18isotopic_constants_PhiConstants;
struct __pyx_t_7brainpy_2_c_18isotopic_constants_IsotopicConstants;

/* "brainpy/_c/isotopic_constants.pxd":6
 * from brainpy._c.double_vector cimport DoubleVector
 * 
 * ctypedef DoubleVector dvec             # <<<<<<<<<<<<<<
 * 
 * 
 */
typedef struct __pyx_t_7brainpy_2_c_13double_vector_DoubleVector __pyx_t_7brainpy_2_c_18isotopic_constants_dvec;

/* "brainpy/_c/isotopic_constants.pxd":9
 * 
 * 
 * cdef struct PolynomialParameters:             # <<<<<<<<<<<<<<
 *     dvec* elementary_symmetric_polynomial
 *     dvec* power_sum
 */
struct __pyx_t_7brainpy_2_c_18isotopic_constants_PolynomialParameters {
  __pyx_t_7brainpy_2_c_18isotopic_constants_dvec *elementary_symmetric_polynomial;
  __pyx_t_7brainpy_2_c_18isotopic_constants_dvec *power_sum;
};

/* "brainpy/_c/isotopic_constants.pxd":14
 * 
 * 
 * cdef struct PhiConstants:             # <<<<<<<<<<<<<<
 *     int order
 *     Element* element
 */
struct __pyx_t_7brainpy_2_c_18isotopic_constants_PhiConstants {
  int order;
  struct __pyx_t_7brainpy_2_c_11composition_Element *element;
  struct __pyx_t_7brainpy_2_c_18isotopic_constants_PolynomialParameters *element_coefficients;
  struct __pyx_t_7brainpy_2_c_18isotopic_constants_PolynomialParameters *mass_coefficients;
};

/* "brainpy/_c/isotopic_constants.pxd":21
 * 
 * 
 * cdef struct IsotopicConstants:             # <<<<<<<<<<<<<<
 *     int order
 *     PhiConstants** constants
 */
struct __pyx_t_7brainpy_2_c_18isotopic_constants_IsotopicConstants {
  int order;
  struct __pyx_t_7brainpy_2_c_18isotopic_constants_PhiConstants **constants;
  size_t size;
  size_t used;
};
struct __pyx_t_7brainpy_2_c_21isotopic_distribution_Peak;
struct __pyx_t_7brainpy_2_c_21isotopic_distribution_PeakList;
struct __pyx_t_7brainpy_2_c_21isotopic_distribution_ElementCache;
struct __pyx_t_7brainpy_2_c_21isotopic_distribution_IsotopicDistribution;
struct __pyx_opt_args_7brainpy_2_c_21isotopic_distribution_make_isotopic_distribution;
struct __pyx_opt_args_7brainpy_2_c_21isotopic_distribution_guess_npeaks;
struct __pyx_opt_args_7brainpy_2_c_21isotopic_distribution__isotopic_variants;
struct __pyx_opt_args_7brainpy_2_c_21isotopic_distribution_isotopic_variants;

/* "brainpy/_c/isotopic_distribution.pxd":7
 * 
 * 
 * cdef struct Peak:             # <<<<<<<<<<<<<<
 *     double mz
 *     double intensity
 */
struct __pyx_t_7brainpy_2_c_21isotopic_distribution_Peak {
  double mz;
  double intensity;
  int charge;
};

/* "brainpy/_c/isotopic_distribution.pxd":13
 * 
 * 
 * cdef struct PeakList:             # <<<<<<<<<<<<<<
 *     Peak* peaks
 *     size_t used
 */
struct __pyx_t_7brainpy_2_c_21isotopic_distribution_PeakList {
  struct __pyx_t_7brainpy_2_c_21isotopic_distribution_Peak *peaks;
  size_t used;
  size_t size;
};

/* "brainpy/_c/isotopic_distribution.pxd":35
 * 
 * 
 * cdef struct ElementCache:             # <<<<<<<<<<<<<<
 *     Element** elements
 *     size_t used
 */
struct __pyx_t_7brainpy_2_c_21isotopic_distribution_ElementCache {
  struct __pyx_t_7brainpy_2_c_11composition_Element **elements;
  size_t used;
  size_t size;
  struct __pyx_t_7brainpy_2_c_11composition_ElementHashTable *source;
};

/* "brainpy/_c/isotopic_distribution.pxd":49
 * 
 * 
 * cdef struct IsotopicDistribution:             # <<<<<<<<<<<<<<
 *     Composition* composition
 *     IsotopicConstants* _isotopic_constants
 */
struct __pyx_t_7brainpy_2_c_21isotopic_distribution_IsotopicDistribution {
  struct __pyx_t_7brainpy_2_c_11composition_Composition *composition;
  struct __pyx_t_7brainpy_2_c_18isotopic_constants_IsotopicConstants *_isotopic_constants;
  int order;
  double average_mass;
  struct __pyx_t_7brainpy_2_c_21isotopic_distribution_Peak *monoisotopic_peak;
  struct __pyx_t_7brainpy_2_c_21isotopic_distribution_ElementCache *cache;
};

/* "brainpy/_c/isotopic_distribution.pxd":58
 * 
 * 
 * cdef IsotopicDistribution* make_isotopic_distribution(Composition* composition, int order, ElementCache* cache=*) nogil             # <<<<<<<<<<<<<<
 * cdef void free_isotopic_distribution(IsotopicDistribution* distribution)  nogil
 * 
 */
struct __pyx_opt_args_7brainpy_2_c_21isotopic_distribution_make_isotopic_distribution {
  int __pyx_n;
  struct __pyx_t_7brainpy_2_c_21isotopic_distribution_ElementCache *cache;
};

/* "brainpy/_c/isotopic_distribution.pxd":77
 * 
 * cdef int max_variants(Composition* composition, ElementCache* cache) nogil
 * cdef int guess_npeaks(Composition* composition_struct, size_t max_npeaks, ElementCache* cache=*) nogil             # <<<<<<<<<<<<<<
 * 
 * cpdef list _isotopic_variants(object composition, object npeaks=*, int charge=*, double charge_carrier=*)
 */
struct __pyx_opt_args_7brainpy_2_c_21isotopic_distribution_guess_npeaks {
  int __pyx_n;
  struct __pyx_t_7brainpy_2_c_21isotopic_distribution_ElementCache *cache;
};

/* "brainpy/_c/isotopic_distribution.pxd":79
 * cdef int guess_npeaks(Composition* composition_struct, size_t max_npeaks, ElementCache* cache=*) nogil
 * 
 * cpdef list _isotopic_variants(object composition, object npeaks=*, int charge=*, double charge_carrier=*)             # <<<<<<<<<<<<<<
 * 
 * 
 */
struct __pyx_opt_args_7brainpy_2_c_21isotopic_distribution__isotopic_variants {
  int __pyx_n;
  PyObject *npeaks;
  int charge;
  double charge_carrier;
};

/* "brainpy/_c/isotopic_distribution.pxd":82
 * 
 * 
 * cdef PeakList* isotopic_variants(Composition* composition, int npeaks, int charge=*, double charge_carrier=*) nogil             # <<<<<<<<<<<<<<
 */
struct __pyx_opt_args_7brainpy_2_c_21isotopic_distribution_isotopic_variants {
  int __pyx_n;
  int charge;
  double charge_carrier;
};
struct __pyx_opt_args_12ms_deisotope_2_c_9averagine_mass_charge_ratio;
struct __pyx_opt_args_12ms_deisotope_2_c_9averagine_neutral_mass;
struct __pyx_opt_args_12ms_deisotope_2_c_9averagine_9Averagine_scale;
struct __pyx_opt_args_12ms_deisotope_2_c_9averagine_9Averagine_isotopic_cluster;
struct __pyx_opt_args_12ms_deisotope_2_c_9averagine_9Averagine__isotopic_cluster;
struct __pyx_opt_args_12ms_deisotope_2_c_9averagine_26TheoreticalIsotopicPattern_ignore_below;
struct __pyx_opt_args_12ms_deisotope_2_c_9averagine_26TheoreticalIsotopicPattern_truncate_after;
struct __pyx_opt_args_12ms_deisotope_2_c_9averagine_26TheoreticalIsotopicPattern_scale;
struct __pyx_opt_args_12ms_deisotope_2_c_9averagine_26TheoreticalIsotopicPattern__scale;
struct __pyx_opt_args_12ms_deisotope_2_c_9averagine_14AveragineCache_has_mz_charge_pair;
struct __pyx_opt_args_12ms_deisotope_2_c_9averagine_14AveragineCache_isotopic_cluster;
struct __pyx_opt_args_12ms_deisotope_2_c_9averagine_isotopic_shift;

/* "ms_deisotope/_c/averagine.pxd":7
 * cdef double PROTON
 * 
 * cdef double mass_charge_ratio(double neutral_mass, int z, double charge_carrier=*)             # <<<<<<<<<<<<<<
 * cdef double neutral_mass(double mz,  int z, double charge_carrier=*)
 * cdef void slide(double mz, list peaklist)
 */
struct __pyx_opt_args_12ms_deisotope_2_c_9averagine_mass_charge_ratio {
  int __pyx_n;
  double charge_carrier;
};

/* "ms_deisotope/_c/averagine.pxd":8
 * 
 * cdef double mass_charge_ratio(double neutral_mass, int z, double charge_carrier=*)
 * cdef double neutral_mass(double mz,  int z, double charge_carrier=*)             # <<<<<<<<<<<<<<
 * cdef void slide(double mz, list peaklist)
 * cdef dict scale_dict(dict data, double factor)
 */
struct __pyx_opt_args_12ms_deisotope_2_c_9averagine_neutral_mass {
  int __pyx_n;
  double charge_carrier;
};

/* "ms_deisotope/_c/averagine.pxd":17
 *         public dict base_composition
 * 
 *     cpdef dict scale(self, double mz, int charge=*, double charge_carrier=*)             # <<<<<<<<<<<<<<
 *     cpdef TheoreticalIsotopicPattern isotopic_cluster(self, double mz, int charge=*, double charge_carrier=*, double truncate_after=*, double ignore_below=*)
 *     cdef TheoreticalIsotopicPattern _isotopic_cluster(self, double mz, int charge=*, double charge_carrier=*, double truncate_after=*, double ignore_below=*)
 */
struct __pyx_opt_args_12ms_deisotope_2_c_9averagine_9Averagine_scale {
  int __pyx_n;
  int charge;
  double charge_carrier;
};

/* "ms_deisotope/_c/averagine.pxd":18
 * 
 *     cpdef dict scale(self, double mz, int charge=*, double charge_carrier=*)
 *     cpdef TheoreticalIsotopicPattern isotopic_cluster(self, double mz, int charge=*, double charge_carrier=*, double truncate_after=*, double ignore_below=*)             # <<<<<<<<<<<<<<
 *     cdef TheoreticalIsotopicPattern _isotopic_cluster(self, double mz, int charge=*, double charge_carrier=*, double truncate_after=*, double ignore_below=*)
 * 
 */
struct __pyx_opt_args_12ms_deisotope_2_c_9averagine_9Averagine_isotopic_cluster {
  int __pyx_n;
  int charge;
  double charge_carrier;
  double truncate_after;
  double ignore_below;
};

/* "ms_deisotope/_c/averagine.pxd":19
 *     cpdef dict scale(self, double mz, int charge=*, double charge_carrier=*)
 *     cpdef TheoreticalIsotopicPattern isotopic_cluster(self, double mz, int charge=*, double charge_carrier=*, double truncate_after=*, double ignore_below=*)
 *     cdef TheoreticalIsotopicPattern _isotopic_cluster(self, double mz, int charge=*, double charge_carrier=*, double truncate_after=*, double ignore_below=*)             # <<<<<<<<<<<<<<
 * 
 * 
 */
struct __pyx_opt_args_12ms_deisotope_2_c_9averagine_9Averagine__isotopic_cluster {
  int __pyx_n;
  int charge;
  double charge_carrier;
  double truncate_after;
  double ignore_below;
};

/* "ms_deisotope/_c/averagine.pxd":39
 *     cdef bint _eq_inst(self, TheoreticalIsotopicPattern other)
 * 
 *     cpdef TheoreticalIsotopicPattern ignore_below(self, double ignore_below=*)             # <<<<<<<<<<<<<<
 *     cpdef TheoreticalIsotopicPattern truncate_after(self, double truncate_after=*)
 *     cpdef TheoreticalIsotopicPattern shift(self, double mz)
 */
struct __pyx_opt_args_12ms_deisotope_2_c_9averagine_26TheoreticalIsotopicPattern_ignore_below {
  int __pyx_n;
  double ignore_below;
};

/* "ms_deisotope/_c/averagine.pxd":40
 * 
 *     cpdef TheoreticalIsotopicPattern ignore_below(self, double ignore_below=*)
 *     cpdef TheoreticalIsotopicPattern truncate_after(self, double truncate_after=*)             # <<<<<<<<<<<<<<
 *     cpdef TheoreticalIsotopicPattern shift(self, double mz)
 *     cpdef TheoreticalIsotopicPattern scale(self, list experimental_distribution, str method=*)
 */
struct __pyx_opt_args_12ms_deisotope_2_c_9averagine_26TheoreticalIsotopicPattern_truncate_after {
  int __pyx_n;
  double truncate_after;
};

/* "ms_deisotope/_c/averagine.pxd":42
 *     cpdef TheoreticalIsotopicPattern truncate_after(self, double truncate_after=*)
 *     cpdef TheoreticalIsotopicPattern shift(self, double mz)
 *     cpdef TheoreticalIsotopicPattern scale(self, list experimental_distribution, str method=*)             # <<<<<<<<<<<<<<
 *     cpdef TheoreticalIsotopicPattern scale_raw(self, double scale_factor)
 *     cpdef double drop_last_peak(self)
 */
struct __pyx_opt_args_12ms_deisotope_2_c_9averagine_26TheoreticalIsotopicPattern_scale {
  int __pyx_n;
  PyObject *method;
};

/* "ms_deisotope/_c/averagine.pxd":53
 * 
 *     @cython.final
 *     cdef inline TheoreticalIsotopicPattern _scale(self, list experimental_distribution, str method=*)             # <<<<<<<<<<<<<<
 * 
 *     @cython.final
 */
struct __pyx_opt_args_12ms_deisotope_2_c_9averagine_26TheoreticalIsotopicPattern__scale {
  int __pyx_n;
  PyObject *method;
};

/* "ms_deisotope/_c/averagine.pxd":88
 *     cdef double _make_cache_key(self, double mz)
 * 
 *     cdef TheoreticalIsotopicPattern has_mz_charge_pair(self, double mz, int charge=*, double charge_carrier=*, double truncate_after=*, double ignore_below=*)             # <<<<<<<<<<<<<<
 *     cpdef TheoreticalIsotopicPattern isotopic_cluster(self, double mz, int charge=*, double charge_carrier=*, double truncate_after=*, double ignore_below=*)
 * 
 */
struct __pyx_opt_args_12ms_deisotope_2_c_9averagine_14AveragineCache_has_mz_charge_pair {
  int __pyx_n;
  int charge;
  double charge_carrier;
  double truncate_after;
  double ignore_below;
};

/* "ms_deisotope/_c/averagine.pxd":89
 * 
 *     cdef TheoreticalIsotopicPattern has_mz_charge_pair(self, double mz, int charge=*, double charge_carrier=*, double truncate_after=*, double ignore_below=*)
 *     cpdef TheoreticalIsotopicPattern isotopic_cluster(self, double mz, int charge=*, double charge_carrier=*, double truncate_after=*, double ignore_below=*)             # <<<<<<<<<<<<<<
 * 
 * 
 */
struct __pyx_opt_args_12ms_deisotope_2_c_9averagine_14AveragineCache_isotopic_cluster {
  int __pyx_n;
  int charge;
  double charge_carrier;
  double truncate_after;
  double ignore_below;
};

/* "ms_deisotope/_c/averagine.pxd":92
 * 
 * 
 * cpdef double isotopic_shift(int charge=*)             # <<<<<<<<<<<<<<
 */
struct __pyx_opt_args_12ms_deisotope_2_c_9averagine_isotopic_shift {
  int __pyx_n;
  int charge;
};
struct __pyx_opt_args_12ms_deisotope_2_c_17deconvoluter_base_16DeconvoluterBase_match_theoretical_isotopic_distribution;
struct __pyx_opt_args_12ms_deisotope_2_c_17deconvoluter_base_16DeconvoluterBase_subtraction;
struct __pyx_opt_args_12ms_deisotope_2_c_17deconvoluter_base_16DeconvoluterBase__find_next_putative_peak;
struct __pyx_opt_args_12ms_deisotope_2_c_17deconvoluter_base_16DeconvoluterBase__find_previous_putative_peak;
struct __pyx_opt_args_12ms_deisotope_2_c_17deconvoluter_base_16DeconvoluterBase__find_next_putative_peak_inplace;
struct __pyx_opt_args_12ms_deisotope_2_c_17deconvoluter_base_16DeconvoluterBase__find_previous_putative_peak_inplace;
struct __pyx_opt_args_12ms_deisotope_2_c_17deconvoluter_base_25AveragineDeconvoluterBase_fit_theoretical_distribution;
struct __pyx_opt_args_12ms_deisotope_2_c_17deconvoluter_base_25AveragineDeconvoluterBase__fit_peaks_at_charges;
struct __pyx_opt_args_12ms_deisotope_2_c_17deconvoluter_base_30MultiAveragineDeconvoluterBase_fit_theoretical_distribution;
struct __pyx_opt_args_12ms_deisotope_2_c_17deconvoluter_base_30MultiAveragineDeconvoluterBase__fit_peaks_at_charges;
struct __pyx_opt_args_12ms_deisotope_2_c_17deconvoluter_base__get_all_peak_charge_pairs;

/* "ms_deisotope/_c/deconvoluter_base.pxd":42
 *     cdef FittedPeak _has_peak(self, double mz, double error_tolerance)
 * 
 *     cpdef list match_theoretical_isotopic_distribution(self, list theoretical_distribution, double error_tolerance=*)             # <<<<<<<<<<<<<<
 *     cpdef scale_theoretical_distribution(self, TheoreticalIsotopicPattern theoretical_distribution, list experimental_distribution)
 *     cpdef IsotopicFitRecord _evaluate_theoretical_distribution(self, list experimental, TheoreticalIsotopicPattern theoretical, FittedPeak peak, int charge)
 */
struct __pyx_opt_args_12ms_deisotope_2_c_17deconvoluter_base_16DeconvoluterBase_match_theoretical_isotopic_distribution {
  int __pyx_n;
  double error_tolerance;
};

/* "ms_deisotope/_c/deconvoluter_base.pxd":45
 *     cpdef scale_theoretical_distribution(self, TheoreticalIsotopicPattern theoretical_distribution, list experimental_distribution)
 *     cpdef IsotopicFitRecord _evaluate_theoretical_distribution(self, list experimental, TheoreticalIsotopicPattern theoretical, FittedPeak peak, int charge)
 *     cpdef subtraction(self, TheoreticalIsotopicPattern isotopic_cluster, double error_tolerance=*)             # <<<<<<<<<<<<<<
 *     cpdef list fit_incremental_truncation(self, IsotopicFitRecord seed_fit, double lower_bound)
 * 
 */
struct __pyx_opt_args_12ms_deisotope_2_c_17deconvoluter_base_16DeconvoluterBase_subtraction {
  int __pyx_n;
  double error_tolerance;
};

/* "ms_deisotope/_c/deconvoluter_base.pxd":50
 *     cpdef bint _check_fit(self, IsotopicFitRecord fit)
 * 
 *     cpdef list _find_next_putative_peak(self, double mz, int charge, int step=*, double tolerance=*)             # <<<<<<<<<<<<<<
 *     cpdef list _find_previous_putative_peak(self, double mz, int charge, int step=*, double tolerance=*)
 * 
 */
struct __pyx_opt_args_12ms_deisotope_2_c_17deconvoluter_base_16DeconvoluterBase__find_next_putative_peak {
  int __pyx_n;
  int step;
  double tolerance;
};

/* "ms_deisotope/_c/deconvoluter_base.pxd":51
 * 
 *     cpdef list _find_next_putative_peak(self, double mz, int charge, int step=*, double tolerance=*)
 *     cpdef list _find_previous_putative_peak(self, double mz, int charge, int step=*, double tolerance=*)             # <<<<<<<<<<<<<<
 * 
 *     cdef int _find_next_putative_peak_inplace(self, double mz, int charge, set result, int step=*, double tolerance=*)
 */
struct __pyx_opt_args_12ms_deisotope_2_c_17deconvoluter_base_16DeconvoluterBase__find_previous_putative_peak {
  int __pyx_n;
  int step;
  double tolerance;
};

/* "ms_deisotope/_c/deconvoluter_base.pxd":53
 *     cpdef list _find_previous_putative_peak(self, double mz, int charge, int step=*, double tolerance=*)
 * 
 *     cdef int _find_next_putative_peak_inplace(self, double mz, int charge, set result, int step=*, double tolerance=*)             # <<<<<<<<<<<<<<
 *     cdef int _find_previous_putative_peak_inplace(self, double mz, int charge, set result, int step=*, double tolerance=*)
 * 
 */
struct __pyx_opt_args_12ms_deisotope_2_c_17deconvoluter_base_16DeconvoluterBase__find_next_putative_peak_inplace {
  int __pyx_n;
  int step;
  double tolerance;
};

/* "ms_deisotope/_c/deconvoluter_base.pxd":54
 * 
 *     cdef int _find_next_putative_peak_inplace(self, double mz, int charge, set result, int step=*, double tolerance=*)
 *     cdef int _find_previous_putative_peak_inplace(self, double mz, int charge, set result, int step=*, double tolerance=*)             # <<<<<<<<<<<<<<
 * 
 * 
 */
struct __pyx_opt_args_12ms_deisotope_2_c_17deconvoluter_base_16DeconvoluterBase__find_previous_putative_peak_inplace {
  int __pyx_n;
  int step;
  double tolerance;
};

/* "ms_deisotope/_c/deconvoluter_base.pxd":61
 *         public AveragineCache averagine
 * 
 *     cpdef IsotopicFitRecord fit_theoretical_distribution(self, FittedPeak peak, double error_tolerance, int charge,             # <<<<<<<<<<<<<<
 *                                                          double charge_carrier=*, double truncate_after=*,
 *                                                          double ignore_below=*)
 */
struct __pyx_opt_args_12ms_deisotope_2_c_17deconvoluter_base_25AveragineDeconvoluterBase_fit_theoretical_distribution {
  int __pyx_n;
  double charge_carrier;
  double truncate_after;
  double ignore_below;
};

/* "ms_deisotope/_c/deconvoluter_base.pxd":65
 *                                                          double ignore_below=*)
 * 
 *     cpdef set _fit_peaks_at_charges(self, set peak_charge_set, double error_tolerance, double charge_carrier=*, double truncate_after=*,             # <<<<<<<<<<<<<<
 *                                     double ignore_below=*)
 * 
 */
struct __pyx_opt_args_12ms_deisotope_2_c_17deconvoluter_base_25AveragineDeconvoluterBase__fit_peaks_at_charges {
  int __pyx_n;
  double charge_carrier;
  double truncate_after;
  double ignore_below;
};

/* "ms_deisotope/_c/deconvoluter_base.pxd":73
 *         public list averagines
 * 
 *     cpdef IsotopicFitRecord fit_theoretical_distribution(self, FittedPeak peak, double error_tolerance, int charge,             # <<<<<<<<<<<<<<
 *                                                          AveragineCache  averagine, double charge_carrier=*, double truncate_after=*,
 *                                                          double ignore_below=*)
 */
struct __pyx_opt_args_12ms_deisotope_2_c_17deconvoluter_base_30MultiAveragineDeconvoluterBase_fit_theoretical_distribution {
  int __pyx_n;
  double charge_carrier;
  double truncate_after;
  double ignore_below;
};

/* "ms_deisotope/_c/deconvoluter_base.pxd":76
 *                                                          AveragineCache  averagine, double charge_carrier=*, double truncate_after=*,
 *                                                          double ignore_below=*)
 *     cpdef set _fit_peaks_at_charges(self, set peak_charge_set, double error_tolerance, double charge_carrier=*, double truncate_after=*,             # <<<<<<<<<<<<<<
 *                                     double ignore_below=*)
 * 
 */
struct __pyx_opt_args_12ms_deisotope_2_c_17deconvoluter_base_30MultiAveragineDeconvoluterBase__fit_peaks_at_charges {
  int __pyx_n;
  double charge_carrier;
  double truncate_after;
  double ignore_below;
};

/* "ms_deisotope/_c/deconvoluter_base.pxd":83
 * 
 * 
 * cpdef set _get_all_peak_charge_pairs(DeconvoluterBase self, FittedPeak peak, double error_tolerance=*,             # <<<<<<<<<<<<<<
 *                                      object charge_range=*,
 *                                      int left_search_limit=*, int right_search_limit=*,
 */
struct __pyx_opt_args_12ms_deisotope_2_c_17deconvoluter_base__get_all_peak_charge_pairs {
  int __pyx_n;
  double error_tolerance;
  PyObject *charge_range;
  int left_search_limit;
  int right_search_limit;
  int recalculate_starting_peak;
  int use_quick_charge;
};
struct __pyx_opt_args_12ms_deisotope_2_c_7scoring_17IsotopicFitRecord__create;
struct __pyx_opt_args_12ms_deisotope_2_c_7scoring_14MSDeconVFitter_score_peak;
struct __pyx_opt_args_12ms_deisotope_2_c_7scoring_21InterferenceDetection_detect_interference;

/* "ms_deisotope/_c/scoring.pxd":29
 * 
 *     @staticmethod
 *     cdef IsotopicFitRecord _create(FittedPeak seed_peak, double score, int charge, TheoreticalIsotopicPattern theoretical,             # <<<<<<<<<<<<<<
 *                                    list experimental, object data=*, int missed_peaks=*)
 * 
 */
struct __pyx_opt_args_12ms_deisotope_2_c_7scoring_17IsotopicFitRecord__create {
  int __pyx_n;
  PyObject *data;
  int missed_peaks;
};

/* "ms_deisotope/_c/scoring.pxd":75
 *     cdef public double mass_error_tolerance
 * 
 *     cdef double score_peak(self, FittedPeak obs, TheoreticalPeak theo, double mass_error_tolerance=*, double minimum_signal_to_noise=*) nogil             # <<<<<<<<<<<<<<
 * 
 * 
 */
struct __pyx_opt_args_12ms_deisotope_2_c_7scoring_14MSDeconVFitter_score_peak {
  int __pyx_n;
  double mass_error_tolerance;
  double minimum_signal_to_noise;
};

/* "ms_deisotope/_c/scoring.pxd":92
 *     cdef public PeakSet peaklist
 * 
 *     cdef double detect_interference(self, list experimental_peaks, double lower=*, double upper=*)             # <<<<<<<<<<<<<<
 * 
 * 
 */
struct __pyx_opt_args_12ms_deisotope_2_c_7scoring_21InterferenceDetection_detect_interference {
  int __pyx_n;
  double lower;
  double upper;
};
struct __pyx_opt_args_12ms_deisotope_2_c_8peak_set_19DeconvolutedPeakSet__has_peak;
struct __pyx_opt_args_12ms_deisotope_2_c_8peak_set_19DeconvolutedPeakSet_has_peak;
struct __pyx_opt_args_12ms_deisotope_2_c_8peak_set_19DeconvolutedPeakSet_all_peaks_for;
struct __pyx_t_12ms_deisotope_2_c_8peak_set_index_cell;
struct __pyx_t_12ms_deisotope_2_c_8peak_set_index_list;

/* "ms_deisotope/_c/peak_set.pxd":82
 *     cpdef DeconvolutedPeakSet copy(self)
 * 
 *     cdef DeconvolutedPeak _has_peak(self, double neutral_mass, double error_tolerance=*, bint use_mz=*)             # <<<<<<<<<<<<<<
 * 
 *     cpdef DeconvolutedPeak has_peak(self, double neutral_mass, double error_tolerance=*, bint use_mz=*)
 */
struct __pyx_opt_args_12ms_deisotope_2_c_8peak_set_19DeconvolutedPeakSet__has_peak {
  int __pyx_n;
  double error_tolerance;
  int use_mz;
};

/* "ms_deisotope/_c/peak_set.pxd":84
 *     cdef DeconvolutedPeak _has_peak(self, double neutral_mass, double error_tolerance=*, bint use_mz=*)
 * 
 *     cpdef DeconvolutedPeak has_peak(self, double neutral_mass, double error_tolerance=*, bint use_mz=*)             # <<<<<<<<<<<<<<
 * 
 *     cpdef tuple all_peaks_for(self, double neutral_mass, double tolerance=*)
 */
struct __pyx_opt_args_12ms_deisotope_2_c_8peak_set_19DeconvolutedPeakSet_has_peak {
  int __pyx_n;
  double error_tolerance;
  int use_mz;
};

/* "ms_deisotope/_c/peak_set.pxd":86
 *     cpdef DeconvolutedPeak has_peak(self, double neutral_mass, double error_tolerance=*, bint use_mz=*)
 * 
 *     cpdef tuple all_peaks_for(self, double neutral_mass, double tolerance=*)             # <<<<<<<<<<<<<<
 * 
 *     cdef DeconvolutedPeak _get_nearest_peak(self, double neutral_mass, double* errout)
 */
struct __pyx_opt_args_12ms_deisotope_2_c_8peak_set_19DeconvolutedPeakSet_all_peaks_for {
  int __pyx_n;
  double tolerance;
};

/* "ms_deisotope/_c/peak_set.pxd":113
 * cdef size_t INTERVAL_INDEX_SIZE
 * 
 * cdef struct index_cell:             # <<<<<<<<<<<<<<
 *     double center_value
 *     size_t start
 */
struct __pyx_t_12ms_deisotope_2_c_8peak_set_index_cell {
  double center_value;
  size_t start;
  size_t end;
};

/* "ms_deisotope/_c/peak_set.pxd":119
 * 
 * 
 * cdef struct index_list:             # <<<<<<<<<<<<<<
 *     index_cell* index
 *     size_t size
 */
struct __pyx_t_12ms_deisotope_2_c_8peak_set_index_list {
  struct __pyx_t_12ms_deisotope_2_c_8peak_set_index_cell *index;
  size_t size;
  double low;
  double high;
};
struct __pyx_opt_args_12ms_deisotope_2_c_18similarity_methods_9PeakMatch__create;
struct __pyx_opt_args_12ms_deisotope_2_c_18similarity_methods_calculate_dot_product;
struct __pyx_opt_args_12ms_deisotope_2_c_18similarity_methods_17SpectrumAlignment_align;
struct __pyx_opt_args_12ms_deisotope_2_c_18similarity_methods_convolve_peak_sets;
struct __pyx_opt_args_12ms_deisotope_2_c_18similarity_methods_convolve_deconvoluted_peak_sets;
struct __pyx_opt_args_12ms_deisotope_2_c_18similarity_methods_convolved_dot_product;
struct __pyx_opt_args_12ms_deisotope_2_c_18similarity_methods_convolve_peak_sets2_fitted;
struct __pyx_opt_args_12ms_deisotope_2_c_18similarity_methods_convolve_peak_sets2_deconvoluted;
struct __pyx_fuse_0__pyx_opt_args_12ms_deisotope_2_c_18similarity_methods_peak_set_similarity;
struct __pyx_fuse_1__pyx_opt_args_12ms_deisotope_2_c_18similarity_methods_peak_set_similarity;
struct __pyx_fuse_2__pyx_opt_args_12ms_deisotope_2_c_18similarity_methods_peak_set_similarity;
struct __pyx_fuse_3__pyx_opt_args_12ms_deisotope_2_c_18similarity_methods_peak_set_similarity;
struct __pyx_fuse_0__pyx_opt_args_12ms_deisotope_2_c_18similarity_methods_bin_peaks;
struct __pyx_fuse_1__pyx_opt_args_12ms_deisotope_2_c_18similarity_methods_bin_peaks;
struct __pyx_fuse_2__pyx_opt_args_12ms_deisotope_2_c_18similarity_methods_bin_peaks;
struct __pyx_fuse_3__pyx_opt_args_12ms_deisotope_2_c_18similarity_methods_bin_peaks;
struct __pyx_fuse_0__pyx_opt_args_12ms_deisotope_2_c_18similarity_methods_ppm_peak_set_similarity;
struct __pyx_fuse_1__pyx_opt_args_12ms_deisotope_2_c_18similarity_methods_ppm_peak_set_similarity;
struct __pyx_fuse_2__pyx_opt_args_12ms_deisotope_2_c_18similarity_methods_ppm_peak_set_similarity;
struct __pyx_fuse_3__pyx_opt_args_12ms_deisotope_2_c_18similarity_methods_ppm_peak_set_similarity;
struct __pyx_fuse_0__pyx_opt_args_12ms_deisotope_2_c_18similarity_methods_align_peaks;
struct __pyx_fuse_1__pyx_opt_args_12ms_deisotope_2_c_18similarity_methods_align_peaks;
struct __pyx_fuse_2__pyx_opt_args_12ms_deisotope_2_c_18similarity_methods_align_peaks;
struct __pyx_fuse_3__pyx_opt_args_12ms_deisotope_2_c_18similarity_methods_align_peaks;

/* "ms_deisotope/_c/similarity_methods.pyx":31
 * 
 * 
 * cpdef enum SimilarityMetrics:             # <<<<<<<<<<<<<<
 *     dot_product
 *     normalized_dot_product
 */
enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_SimilarityMetrics {
  __pyx_e_12ms_deisotope_2_c_18similarity_methods_dot_product,
  __pyx_e_12ms_deisotope_2_c_18similarity_methods_normalized_dot_product
};

/* "ms_deisotope/_c/similarity_methods.pyx":36
 * 
 * 
 * cpdef enum PeakType:             # <<<<<<<<<<<<<<
 *     Fitted
 *     Deconvoluted
 */
enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType {
  __pyx_e_12ms_deisotope_2_c_18similarity_methods_Fitted,
  __pyx_e_12ms_deisotope_2_c_18similarity_methods_Deconvoluted
};

/* "ms_deisotope/_c/similarity_methods.pyx":80
 * 
 *     @staticmethod
 *     cdef PeakMatch _create(PeakBase peak_a, PeakBase peak_b, double score=0.0):             # <<<<<<<<<<<<<<
 *         cdef PeakMatch self = PeakMatch.__new__(PeakMatch)
 *         self.peak_a = peak_a
 */
struct __pyx_opt_args_12ms_deisotope_2_c_18similarity_methods_9PeakMatch__create {
  int __pyx_n;
  double score;
};

/* "ms_deisotope/_c/similarity_methods.pyx":328
 * @cython.boundscheck(False)
 * @cython.cdivision(True)
 * cdef double calculate_dot_product(cnp.ndarray[double, ndim=1] bin_a, cnp.ndarray[double, ndim=1] bin_b, bint normalize=True):             # <<<<<<<<<<<<<<
 *     cdef:
 *         double n_a, n_b, n_ab, z, a, b
 */
struct __pyx_opt_args_12ms_deisotope_2_c_18similarity_methods_calculate_dot_product {
  int __pyx_n;
  int normalize;
};

/* "ms_deisotope/_c/similarity_methods.pyx":387
 *                 "Peak set types must match, got %s and %s" % (type(self.peak_set_a), type(self.peak_set_b)))
 * 
 *     cpdef align(self, double error_tolerance=2e-5, double shift=0.0):             # <<<<<<<<<<<<<<
 *         cdef:
 *             list pairs
 */
struct __pyx_opt_args_12ms_deisotope_2_c_18similarity_methods_17SpectrumAlignment_align {
  int __pyx_n;
  double error_tolerance;
  double shift;
};

/* "ms_deisotope/_c/similarity_methods.pyx":415
 * 
 * 
 * cdef list convolve_peak_sets(PeakSet peak_set_a, PeakSet peak_set_b, double error_tolerance=2e-5, double shift=0.0):             # <<<<<<<<<<<<<<
 *     cdef:
 *         size_t i, n, j, m
 */
struct __pyx_opt_args_12ms_deisotope_2_c_18similarity_methods_convolve_peak_sets {
  int __pyx_n;
  double error_tolerance;
  double shift;
};

/* "ms_deisotope/_c/similarity_methods.pyx":439
 * 
 * 
 * cdef list convolve_deconvoluted_peak_sets(DeconvolutedPeakSet peak_set_a, DeconvolutedPeakSet peak_set_b,             # <<<<<<<<<<<<<<
 *                                           double error_tolerance=2e-5, double shift=0.0):
 *     cdef:
 */
struct __pyx_opt_args_12ms_deisotope_2_c_18similarity_methods_convolve_deconvoluted_peak_sets {
  int __pyx_n;
  double error_tolerance;
  double shift;
};

/* "ms_deisotope/_c/similarity_methods.pyx":463
 * 
 * 
 * cdef double convolved_dot_product(list peak_pairs, PeakType peak_type=PeakType.Fitted):             # <<<<<<<<<<<<<<
 *     cdef:
 *         size_t i, n
 */
struct __pyx_opt_args_12ms_deisotope_2_c_18similarity_methods_convolved_dot_product {
  int __pyx_n;
  enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType peak_type;
};

/* "ms_deisotope/_c/similarity_methods.pyx":503
 * 
 * 
 * cdef double convolve_peak_sets2_fitted(PeakSet peak_set_a, PeakSet peak_set_b, double error_tolerance=2e-5):             # <<<<<<<<<<<<<<
 *     cdef:
 *         size_t i, n, j, m
 */
struct __pyx_opt_args_12ms_deisotope_2_c_18similarity_methods_convolve_peak_sets2_fitted {
  int __pyx_n;
  double error_tolerance;
};

/* "ms_deisotope/_c/similarity_methods.pyx":524
 * 
 * 
 * cdef double convolve_peak_sets2_deconvoluted(DeconvolutedPeakSet peak_set_a, DeconvolutedPeakSet peak_set_b,             # <<<<<<<<<<<<<<
 *                                              double error_tolerance=2e-5):
 *     cdef:
 */
struct __pyx_opt_args_12ms_deisotope_2_c_18similarity_methods_convolve_peak_sets2_deconvoluted {
  int __pyx_n;
  double error_tolerance;
};

/* "ms_deisotope/_c/similarity_methods.pyx":126
 * @cython.boundscheck(False)
 * @cython.cdivision(True)
 * cpdef double peak_set_similarity(peak_collection peak_set_a, peak_collection peak_set_b, int precision=0) except -1:             # <<<<<<<<<<<<<<
 *     """Computes the normalized dot product, also called cosine similarity between
 *     two peak sets, a similarity metric ranging between 0 (dissimilar) to 1.0 (similar).
 */
struct __pyx_fuse_0__pyx_opt_args_12ms_deisotope_2_c_18similarity_methods_peak_set_similarity {
  int __pyx_n;
  int precision;
};
struct __pyx_fuse_1__pyx_opt_args_12ms_deisotope_2_c_18similarity_methods_peak_set_similarity {
  int __pyx_n;
  int precision;
};
struct __pyx_fuse_2__pyx_opt_args_12ms_deisotope_2_c_18similarity_methods_peak_set_similarity {
  int __pyx_n;
  int precision;
};
struct __pyx_fuse_3__pyx_opt_args_12ms_deisotope_2_c_18similarity_methods_peak_set_similarity {
  int __pyx_n;
  int precision;
};

/* "ms_deisotope/_c/similarity_methods.pyx":257
 * 
 * @cython.boundscheck(False)
 * cpdef tuple bin_peaks(peak_collection peak_set_a, peak_collection peak_set_b, int precision=0):             # <<<<<<<<<<<<<<
 *     cdef:
 *         double hi, scaler
 */
struct __pyx_fuse_0__pyx_opt_args_12ms_deisotope_2_c_18similarity_methods_bin_peaks {
  int __pyx_n;
  int precision;
};
struct __pyx_fuse_1__pyx_opt_args_12ms_deisotope_2_c_18similarity_methods_bin_peaks {
  int __pyx_n;
  int precision;
};
struct __pyx_fuse_2__pyx_opt_args_12ms_deisotope_2_c_18similarity_methods_bin_peaks {
  int __pyx_n;
  int precision;
};
struct __pyx_fuse_3__pyx_opt_args_12ms_deisotope_2_c_18similarity_methods_bin_peaks {
  int __pyx_n;
  int precision;
};

/* "ms_deisotope/_c/similarity_methods.pyx":545
 * 
 * 
 * cpdef double ppm_peak_set_similarity(peak_collection peak_set_a, peak_collection peak_set_b, double error_tolerance=2e-5):             # <<<<<<<<<<<<<<
 *     cdef:
 *         double ab, aa, bb
 */
struct __pyx_fuse_0__pyx_opt_args_12ms_deisotope_2_c_18similarity_methods_ppm_peak_set_similarity {
  int __pyx_n;
  double error_tolerance;
};
struct __pyx_fuse_1__pyx_opt_args_12ms_deisotope_2_c_18similarity_methods_ppm_peak_set_similarity {
  int __pyx_n;
  double error_tolerance;
};
struct __pyx_fuse_2__pyx_opt_args_12ms_deisotope_2_c_18similarity_methods_ppm_peak_set_similarity {
  int __pyx_n;
  double error_tolerance;
};
struct __pyx_fuse_3__pyx_opt_args_12ms_deisotope_2_c_18similarity_methods_ppm_peak_set_similarity {
  int __pyx_n;
  double error_tolerance;
};

/* "ms_deisotope/_c/similarity_methods.pyx":566
 * 
 * 
 * cpdef SpectrumAlignment align_peaks(peak_collection peak_set_a, peak_collection peak_set_b, double error_tolerance=2e-5, double shift=0.0):             # <<<<<<<<<<<<<<
 *     if peak_collection is PeakSet or peak_collection is DeconvolutedPeakSet:
 *         return SpectrumAlignment(peak_set_a, peak_set_b, error_tolerance, shift)
 */
struct __pyx_fuse_0__pyx_opt_args_12ms_deisotope_2_c_18similarity_methods_align_peaks {
  int __pyx_n;
  double error_tolerance;
  double shift;
};
struct __pyx_fuse_1__pyx_opt_args_12ms_deisotope_2_c_18similarity_methods_align_peaks {
  int __pyx_n;
  double error_tolerance;
  double shift;
};
struct __pyx_fuse_2__pyx_opt_args_12ms_deisotope_2_c_18similarity_methods_align_peaks {
  int __pyx_n;
  double error_tolerance;
  double shift;
};
struct __pyx_fuse_3__pyx_opt_args_12ms_deisotope_2_c_18similarity_methods_align_peaks {
  int __pyx_n;
  double error_tolerance;
  double shift;
};

/* "ms_peak_picker/_c/peak_set.pxd":2
 * 
 * cdef class PeakBase(object):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public double mz
 */
struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakBase {
  PyObject_HEAD
  struct __pyx_vtabstruct_14ms_peak_picker_2_c_8peak_set_PeakBase *__pyx_vtab;
  double mz;
  double intensity;
  double area;
};


/* "ms_peak_picker/_c/peak_set.pxd":12
 * 
 * 
 * cdef class FittedPeak(PeakBase):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public double signal_to_noise
 */
struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_FittedPeak {
  struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakBase __pyx_base;
  double signal_to_noise;
  double full_width_at_half_max;
  double left_width;
  double right_width;
  long peak_count;
  long index;
};


/* "ms_peak_picker/_c/peak_set.pxd":29
 *                             double area)
 * 
 * cdef class PeakSet(object):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public tuple peaks
 */
struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSet {
  PyObject_HEAD
  struct __pyx_vtabstruct_14ms_peak_picker_2_c_8peak_set_PeakSet *__pyx_vtab;
  PyObject *peaks;
  int indexed;
};


/* "ms_peak_picker/_c/peak_set.pxd":83
 * 
 * 
 * cdef class PeakSetIndexed(PeakSet):             # <<<<<<<<<<<<<<
 *     cdef:
 *         double* mz_index
 */
struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSetIndexed {
  struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSet __pyx_base;
  double *mz_index;
  struct __pyx_t_14ms_peak_picker_2_c_8peak_set_index_list *interval_index;
};


/* "ms_peak_picker/_c/peak_index.pxd":5
 * 
 * 
 * cdef class PeakIndex(object):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public np.ndarray mz_array
 */
struct __pyx_obj_14ms_peak_picker_2_c_10peak_index_PeakIndex {
  PyObject_HEAD
  struct __pyx_vtabstruct_14ms_peak_picker_2_c_10peak_index_PeakIndex *__pyx_vtab;
  PyArrayObject *mz_array;
  PyArrayObject *intensity_array;
  struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSet *peaks;
};


/* "brainpy/_c/composition.pxd":123
 * 
 * 
 * cdef class PyComposition(object):             # <<<<<<<<<<<<<<
 *     cdef:
 *         Composition* impl
 */
struct __pyx_obj_7brainpy_2_c_11composition_PyComposition {
  PyObject_HEAD
  struct __pyx_vtabstruct_7brainpy_2_c_11composition_PyComposition *__pyx_vtab;
  struct __pyx_t_7brainpy_2_c_11composition_Composition *impl;
  double cached_mass;
  int _clean;
};


/* "brainpy/_c/isotopic_distribution.pxd":63
 * 
 * @freelist(100000)
 * cdef class TheoreticalPeak(object):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public double mz
 */
struct __pyx_obj_7brainpy_2_c_21isotopic_distribution_TheoreticalPeak {
  PyObject_HEAD
  struct __pyx_vtabstruct_7brainpy_2_c_21isotopic_distribution_TheoreticalPeak *__pyx_vtab;
  double mz;
  double intensity;
  int charge;
};


/* "ms_deisotope/_c/averagine.pxd":12
 * cdef dict scale_dict(dict data, double factor)
 * 
 * cdef class Averagine(object):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public double base_mass
 */
struct __pyx_obj_12ms_deisotope_2_c_9averagine_Averagine {
  PyObject_HEAD
  struct __pyx_vtabstruct_12ms_deisotope_2_c_9averagine_Averagine *__pyx_vtab;
  double base_mass;
  PyObject *base_composition;
};


/* "ms_deisotope/_c/averagine.pxd":23
 * 
 * @cython.final
 * cdef class TheoreticalIsotopicPattern(object):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public list peaklist
 */
struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern {
  PyObject_HEAD
  struct __pyx_vtabstruct_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *__pyx_vtab;
  PyObject *peaklist;
  double origin;
  double offset;
};


/* "ms_deisotope/_c/averagine.pxd":79
 * 
 * @cython.final
 * cdef class AveragineCache(object):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public dict backend
 */
struct __pyx_obj_12ms_deisotope_2_c_9averagine_AveragineCache {
  PyObject_HEAD
  struct __pyx_vtabstruct_12ms_deisotope_2_c_9averagine_AveragineCache *__pyx_vtab;
  PyObject *backend;
  struct __pyx_obj_12ms_deisotope_2_c_9averagine_Averagine *averagine;
  double cache_truncation;
  int enabled;
};


/* "ms_deisotope/_c/deconvoluter_base.pxd":25
 * 
 * 
 * cdef class DeconvoluterBase(object):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public bint use_subtraction
 */
struct __pyx_obj_12ms_deisotope_2_c_17deconvoluter_base_DeconvoluterBase {
  PyObject_HEAD
  struct __pyx_vtabstruct_12ms_deisotope_2_c_17deconvoluter_base_DeconvoluterBase *__pyx_vtab;
  int use_subtraction;
  PyObject *scale_method;
  int merge_isobaric_peaks;
  double minimum_intensity;
  struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSet *peaklist;
  struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitterBase *scorer;
  int verbose;
  PyObject *_slice_cache;
};


/* "ms_deisotope/_c/deconvoluter_base.pxd":57
 * 
 * 
 * cdef class AveragineDeconvoluterBase(DeconvoluterBase):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public AveragineCache averagine
 */
struct __pyx_obj_12ms_deisotope_2_c_17deconvoluter_base_AveragineDeconvoluterBase {
  struct __pyx_obj_12ms_deisotope_2_c_17deconvoluter_base_DeconvoluterBase __pyx_base;
  struct __pyx_obj_12ms_deisotope_2_c_9averagine_AveragineCache *averagine;
};


/* "ms_deisotope/_c/deconvoluter_base.pxd":69
 * 
 * 
 * cdef class MultiAveragineDeconvoluterBase(DeconvoluterBase):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public list averagines
 */
struct __pyx_obj_12ms_deisotope_2_c_17deconvoluter_base_MultiAveragineDeconvoluterBase {
  struct __pyx_obj_12ms_deisotope_2_c_17deconvoluter_base_DeconvoluterBase __pyx_base;
  PyObject *averagines;
};


/* "ms_deisotope/_c/deconvoluter_base.pxd":91
 * 
 * 
 * cdef class ChargeIterator(object):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public int lower
 */
struct __pyx_obj_12ms_deisotope_2_c_17deconvoluter_base_ChargeIterator {
  PyObject_HEAD
  struct __pyx_vtabstruct_12ms_deisotope_2_c_17deconvoluter_base_ChargeIterator *__pyx_vtab;
  int lower;
  int upper;
  int sign;
  int *values;
  size_t size;
  size_t index;
};


/* "ms_deisotope/_c/scoring.pxd":16
 * 
 * 
 * cdef class IsotopicFitRecord(object):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public FittedPeak seed_peak
 */
struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitRecord {
  PyObject_HEAD
  struct __pyx_vtabstruct_12ms_deisotope_2_c_7scoring_IsotopicFitRecord *__pyx_vtab;
  struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_FittedPeak *seed_peak;
  double score;
  int charge;
  PyObject *experimental;
  struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *theoretical;
  struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_FittedPeak *monoisotopic_peak;
  int missed_peaks;
  PyObject *data;
  Py_hash_t _hash;
};


/* "ms_deisotope/_c/scoring.pxd":38
 * 
 * 
 * cdef class FitSelectorBase(object):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public double minimum_score
 */
struct __pyx_obj_12ms_deisotope_2_c_7scoring_FitSelectorBase {
  PyObject_HEAD
  struct __pyx_vtabstruct_12ms_deisotope_2_c_7scoring_FitSelectorBase *__pyx_vtab;
  double minimum_score;
};


/* "ms_deisotope/_c/scoring.pxd":50
 * 
 * 
 * cdef class IsotopicFitterBase(object):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public FitSelectorBase select
 */
struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitterBase {
  PyObject_HEAD
  struct __pyx_vtabstruct_12ms_deisotope_2_c_7scoring_IsotopicFitterBase *__pyx_vtab;
  struct __pyx_obj_12ms_deisotope_2_c_7scoring_FitSelectorBase *select;
};


/* "ms_deisotope/_c/scoring.pxd":62
 * 
 * 
 * cdef class LeastSquaresFitter(IsotopicFitterBase):             # <<<<<<<<<<<<<<
 *     pass
 * 
 */
struct __pyx_obj_12ms_deisotope_2_c_7scoring_LeastSquaresFitter {
  struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitterBase __pyx_base;
};


/* "ms_deisotope/_c/scoring.pxd":66
 * 
 * 
 * cdef class GTestFitter(IsotopicFitterBase):             # <<<<<<<<<<<<<<
 *     pass
 * 
 */
struct __pyx_obj_12ms_deisotope_2_c_7scoring_GTestFitter {
  struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitterBase __pyx_base;
};


/* "ms_deisotope/_c/scoring.pxd":69
 *     pass
 * 
 * cdef class ScaledGTestFitter(IsotopicFitterBase):             # <<<<<<<<<<<<<<
 *     pass
 * 
 */
struct __pyx_obj_12ms_deisotope_2_c_7scoring_ScaledGTestFitter {
  struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitterBase __pyx_base;
};


/* "ms_deisotope/_c/scoring.pxd":72
 *     pass
 * 
 * cdef class MSDeconVFitter(IsotopicFitterBase):             # <<<<<<<<<<<<<<
 *     cdef public double mass_error_tolerance
 * 
 */
struct __pyx_obj_12ms_deisotope_2_c_7scoring_MSDeconVFitter {
  struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitterBase __pyx_base;
  double mass_error_tolerance;
};


/* "ms_deisotope/_c/scoring.pxd":78
 * 
 * 
 * cdef class PenalizedMSDeconVFitter(IsotopicFitterBase):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public double mass_error_tolerance
 */
struct __pyx_obj_12ms_deisotope_2_c_7scoring_PenalizedMSDeconVFitter {
  struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitterBase __pyx_base;
  double mass_error_tolerance;
  double penalty_factor;
};


/* "ms_deisotope/_c/scoring.pxd":84
 * 
 * 
 * cdef class FunctionScorer(IsotopicFitterBase):             # <<<<<<<<<<<<<<
 *     cdef:
 *         object function
 */
struct __pyx_obj_12ms_deisotope_2_c_7scoring_FunctionScorer {
  struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitterBase __pyx_base;
  PyObject *function;
};


/* "ms_deisotope/_c/scoring.pxd":89
 * 
 * 
 * cdef class InterferenceDetection(object):             # <<<<<<<<<<<<<<
 *     cdef public PeakSet peaklist
 * 
 */
struct __pyx_obj_12ms_deisotope_2_c_7scoring_InterferenceDetection {
  PyObject_HEAD
  struct __pyx_vtabstruct_12ms_deisotope_2_c_7scoring_InterferenceDetection *__pyx_vtab;
  struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSet *peaklist;
};


/* "ms_deisotope/_c/scoring.pxd":95
 * 
 * 
 * cdef class DistinctPatternFitter(IsotopicFitterBase):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public InterferenceDetection interference_detector
 */
struct __pyx_obj_12ms_deisotope_2_c_7scoring_DistinctPatternFitter {
  struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitterBase __pyx_base;
  struct __pyx_obj_12ms_deisotope_2_c_7scoring_InterferenceDetection *interference_detector;
  struct __pyx_obj_12ms_deisotope_2_c_7scoring_ScaledGTestFitter *g_test_scaled;
  double peak_count_scale;
  double domain_scale;
};


/* "ms_deisotope/_c/scoring.pxd":102
 *         public double domain_scale
 * 
 * cdef class ScaledPenalizedMSDeconvFitter(IsotopicFitterBase):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public double scale_factor
 */
struct __pyx_obj_12ms_deisotope_2_c_7scoring_ScaledPenalizedMSDeconvFitter {
  struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitterBase __pyx_base;
  double scale_factor;
  struct __pyx_obj_12ms_deisotope_2_c_7scoring_PenalizedMSDeconVFitter *scorer;
};


/* "ms_deisotope/_c/scoring.pxd":112
 * 
 * 
 * cdef class DotProductFitter(IsotopicFitterBase):             # <<<<<<<<<<<<<<
 *     pass
 */
struct __pyx_obj_12ms_deisotope_2_c_7scoring_DotProductFitter {
  struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitterBase __pyx_base;
};


/* "ms_deisotope/_c/peak_set.pxd":5
 * 
 * 
 * cdef class _Index:             # <<<<<<<<<<<<<<
 *     cdef:
 *         public size_t neutral_mass
 */
struct __pyx_obj_12ms_deisotope_2_c_8peak_set__Index {
  PyObject_HEAD
  struct __pyx_vtabstruct_12ms_deisotope_2_c_8peak_set__Index *__pyx_vtab;
  size_t neutral_mass;
  size_t mz;
};


/* "ms_deisotope/_c/peak_set.pxd":14
 * 
 * 
 * cdef class EnvelopePair:             # <<<<<<<<<<<<<<
 *     cdef:
 *         public double mz
 */
struct __pyx_obj_12ms_deisotope_2_c_8peak_set_EnvelopePair {
  PyObject_HEAD
  struct __pyx_vtabstruct_12ms_deisotope_2_c_8peak_set_EnvelopePair *__pyx_vtab;
  double mz;
  double intensity;
};


/* "ms_deisotope/_c/peak_set.pxd":25
 * 
 * 
 * cdef class Envelope:             # <<<<<<<<<<<<<<
 *     cdef public tuple pairs
 * 
 */
struct __pyx_obj_12ms_deisotope_2_c_8peak_set_Envelope {
  PyObject_HEAD
  struct __pyx_vtabstruct_12ms_deisotope_2_c_8peak_set_Envelope *__pyx_vtab;
  PyObject *pairs;
};


/* "ms_deisotope/_c/peak_set.pxd":40
 * 
 * 
 * cdef class DeconvolutedPeak(PeakBase):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public double neutral_mass
 */
struct __pyx_obj_12ms_deisotope_2_c_8peak_set_DeconvolutedPeak {
  struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakBase __pyx_base;
  double neutral_mass;
  double signal_to_noise;
  struct __pyx_obj_12ms_deisotope_2_c_8peak_set__Index *_index;
  double full_width_at_half_max;
  int charge;
  double a_to_a2_ratio;
  double most_abundant_mass;
  double average_mass;
  double score;
  struct __pyx_obj_12ms_deisotope_2_c_8peak_set_Envelope *envelope;
  struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitRecord *fit;
  int chosen_for_msms;
};


/* "ms_deisotope/_c/peak_set.pxd":66
 * 
 * 
 * cdef class DeconvolutedPeakSolution(DeconvolutedPeak):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public object solution
 */
struct __pyx_obj_12ms_deisotope_2_c_8peak_set_DeconvolutedPeakSolution {
  struct __pyx_obj_12ms_deisotope_2_c_8peak_set_DeconvolutedPeak __pyx_base;
  PyObject *solution;
};


/* "ms_deisotope/_c/peak_set.pxd":70
 *         public object solution
 * 
 * cdef class DeconvolutedPeakSet(object):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public tuple peaks
 */
struct __pyx_obj_12ms_deisotope_2_c_8peak_set_DeconvolutedPeakSet {
  PyObject_HEAD
  struct __pyx_vtabstruct_12ms_deisotope_2_c_8peak_set_DeconvolutedPeakSet *__pyx_vtab;
  PyObject *peaks;
  PyObject *_mz_ordered;
  int indexed;
};


/* "ms_deisotope/_c/peak_set.pxd":99
 * 
 * 
 * cdef class DeconvolutedPeakSetIndexed(DeconvolutedPeakSet):             # <<<<<<<<<<<<<<
 *     cdef:
 *         double* neutral_mass_array
 */
struct __pyx_obj_12ms_deisotope_2_c_8peak_set_DeconvolutedPeakSetIndexed {
  struct __pyx_obj_12ms_deisotope_2_c_8peak_set_DeconvolutedPeakSet __pyx_base;
  double *neutral_mass_array;
  double *mz_array;
  struct __pyx_t_12ms_deisotope_2_c_8peak_set_index_list *interval_index;
  size_t _size;
};


/* "ms_deisotope/_c/similarity_methods.pyx":43
 * @cython.freelist(10000)
 * @cython.final
 * cdef class PeakMatch(object):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public PeakBase peak_a
 */
struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_PeakMatch {
  PyObject_HEAD
  struct __pyx_vtabstruct_12ms_deisotope_2_c_18similarity_methods_PeakMatch *__pyx_vtab;
  struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakBase *peak_a;
  struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakBase *peak_b;
  double score;
};


/* "ms_deisotope/_c/similarity_methods.pyx":352
 * 
 * 
 * cdef class SpectrumAlignment(object):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public list peak_pairs
 */
struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_SpectrumAlignment {
  PyObject_HEAD
  struct __pyx_vtabstruct_12ms_deisotope_2_c_18similarity_methods_SpectrumAlignment *__pyx_vtab;
  PyObject *peak_pairs;
  double shift;
  double score;
  PyObject *peak_set_a;
  PyObject *peak_set_b;
  enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType peak_type;
};


/* "EnumBase":15
 * 
 * @cython.internal
 * cdef class __Pyx_EnumMeta(type):             # <<<<<<<<<<<<<<
 *     def __init__(cls, name, parents, dct):
 *         type.__init__(cls, name, parents, dct)
 */
struct __pyx_obj___Pyx_EnumMeta {
  PyHeapTypeObject __pyx_base;
};



/* "ms_peak_picker/_c/peak_set.pxd":2
 * 
 * cdef class PeakBase(object):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public double mz
 */

struct __pyx_vtabstruct_14ms_peak_picker_2_c_8peak_set_PeakBase {
  struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakBase *(*clone)(struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakBase *, int __pyx_skip_dispatch);
  struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakBase *(*copy)(struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakBase *, int __pyx_skip_dispatch);
};
static struct __pyx_vtabstruct_14ms_peak_picker_2_c_8peak_set_PeakBase *__pyx_vtabptr_14ms_peak_picker_2_c_8peak_set_PeakBase;


/* "ms_peak_picker/_c/peak_set.pxd":12
 * 
 * 
 * cdef class FittedPeak(PeakBase):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public double signal_to_noise
 */

struct __pyx_vtabstruct_14ms_peak_picker_2_c_8peak_set_FittedPeak {
  struct __pyx_vtabstruct_14ms_peak_picker_2_c_8peak_set_PeakBase __pyx_base;
  int (*_eq)(struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_FittedPeak *, struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_FittedPeak *, int __pyx_skip_dispatch);
  struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_FittedPeak *(*_create)(double, double, double, double, double, double, long, long, double);
};
static struct __pyx_vtabstruct_14ms_peak_picker_2_c_8peak_set_FittedPeak *__pyx_vtabptr_14ms_peak_picker_2_c_8peak_set_FittedPeak;


/* "ms_peak_picker/_c/peak_set.pxd":29
 *                             double area)
 * 
 * cdef class PeakSet(object):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public tuple peaks
 */

struct __pyx_vtabstruct_14ms_peak_picker_2_c_8peak_set_PeakSet {
  struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSet *(*_create)(PyObject *);
  PyObject *(*reindex)(struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSet *, int __pyx_skip_dispatch);
  size_t (*_index)(struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSet *, int __pyx_skip_dispatch);
  struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_FittedPeak *(*_get_nearest_peak)(struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSet *, double, double *);
  struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_FittedPeak *(*_has_peak)(struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSet *, double, struct __pyx_opt_args_14ms_peak_picker_2_c_8peak_set_7PeakSet__has_peak *__pyx_optional_args);
  struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSet *(*clone)(struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSet *, int __pyx_skip_dispatch);
  struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSet *(*copy)(struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSet *, int __pyx_skip_dispatch);
  struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSet *(*_between)(struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSet *, double, double);
  int (*_between_bounds)(struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSet *, double, double, size_t *, size_t *);
  PyObject *(*all_peaks_for)(struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSet *, double, int __pyx_skip_dispatch, struct __pyx_opt_args_14ms_peak_picker_2_c_8peak_set_7PeakSet_all_peaks_for *__pyx_optional_args);
  struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_FittedPeak *(*getitem)(struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSet *, size_t);
  size_t (*get_size)(struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSet *);
  int (*_eq)(struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSet *, struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSet *, int __pyx_skip_dispatch);
};
static struct __pyx_vtabstruct_14ms_peak_picker_2_c_8peak_set_PeakSet *__pyx_vtabptr_14ms_peak_picker_2_c_8peak_set_PeakSet;


/* "ms_peak_picker/_c/peak_set.pxd":83
 * 
 * 
 * cdef class PeakSetIndexed(PeakSet):             # <<<<<<<<<<<<<<
 *     cdef:
 *         double* mz_index
 */

struct __pyx_vtabstruct_14ms_peak_picker_2_c_8peak_set_PeakSetIndexed {
  struct __pyx_vtabstruct_14ms_peak_picker_2_c_8peak_set_PeakSet __pyx_base;
  PyObject *(*_allocate_index)(struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSetIndexed *, size_t, int __pyx_skip_dispatch);
  struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_FittedPeak *(*has_peak_hinted)(struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSetIndexed *, double, int __pyx_skip_dispatch, struct __pyx_opt_args_14ms_peak_picker_2_c_8peak_set_14PeakSetIndexed_has_peak_hinted *__pyx_optional_args);
};
static struct __pyx_vtabstruct_14ms_peak_picker_2_c_8peak_set_PeakSetIndexed *__pyx_vtabptr_14ms_peak_picker_2_c_8peak_set_PeakSetIndexed;


/* "ms_peak_picker/_c/peak_index.pxd":5
 * 
 * 
 * cdef class PeakIndex(object):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public np.ndarray mz_array
 */

struct __pyx_vtabstruct_14ms_peak_picker_2_c_10peak_index_PeakIndex {
  struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_FittedPeak *(*_has_peak)(struct __pyx_obj_14ms_peak_picker_2_c_10peak_index_PeakIndex *, double, struct __pyx_opt_args_14ms_peak_picker_2_c_10peak_index_9PeakIndex__has_peak *__pyx_optional_args);
  struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSet *(*_between)(struct __pyx_obj_14ms_peak_picker_2_c_10peak_index_PeakIndex *, double, double);
  PyObject *(*all_peaks_for)(struct __pyx_obj_14ms_peak_picker_2_c_10peak_index_PeakIndex *, double, int __pyx_skip_dispatch, struct __pyx_opt_args_14ms_peak_picker_2_c_10peak_index_9PeakIndex_all_peaks_for *__pyx_optional_args);
  size_t (*get_size)(struct __pyx_obj_14ms_peak_picker_2_c_10peak_index_PeakIndex *);
  struct __pyx_obj_14ms_peak_picker_2_c_10peak_index_PeakIndex *(*clone)(struct __pyx_obj_14ms_peak_picker_2_c_10peak_index_PeakIndex *, int __pyx_skip_dispatch);
  struct __pyx_obj_14ms_peak_picker_2_c_10peak_index_PeakIndex *(*copy)(struct __pyx_obj_14ms_peak_picker_2_c_10peak_index_PeakIndex *, int __pyx_skip_dispatch);
};
static struct __pyx_vtabstruct_14ms_peak_picker_2_c_10peak_index_PeakIndex *__pyx_vtabptr_14ms_peak_picker_2_c_10peak_index_PeakIndex;


/* "brainpy/_c/composition.pxd":123
 * 
 * 
 * cdef class PyComposition(object):             # <<<<<<<<<<<<<<
 *     cdef:
 *         Composition* impl
 */

struct __pyx_vtabstruct_7brainpy_2_c_11composition_PyComposition {
  struct __pyx_obj_7brainpy_2_c_11composition_PyComposition *(*_create)(struct __pyx_t_7brainpy_2_c_11composition_Composition *);
  void (*_set_impl)(struct __pyx_obj_7brainpy_2_c_11composition_PyComposition *, struct __pyx_t_7brainpy_2_c_11composition_Composition *, struct __pyx_opt_args_7brainpy_2_c_11composition_13PyComposition__set_impl *__pyx_optional_args);
  void (*_initialize_from_formula)(struct __pyx_obj_7brainpy_2_c_11composition_PyComposition *, PyObject *);
  double (*mass)(struct __pyx_obj_7brainpy_2_c_11composition_PyComposition *, int __pyx_skip_dispatch);
  int (*__pyx___equality_pycomposition)(struct __pyx_obj_7brainpy_2_c_11composition_PyComposition *, struct __pyx_obj_7brainpy_2_c_11composition_PyComposition *, int __pyx_skip_dispatch);
  int (*__pyx___equality_dict)(struct __pyx_obj_7brainpy_2_c_11composition_PyComposition *, PyObject *, int __pyx_skip_dispatch);
  struct __pyx_obj_7brainpy_2_c_11composition_PyComposition *(*copy)(struct __pyx_obj_7brainpy_2_c_11composition_PyComposition *, int __pyx_skip_dispatch);
  PyObject *(*update)(struct __pyx_obj_7brainpy_2_c_11composition_PyComposition *, PyObject *, int __pyx_skip_dispatch);
  PyObject *(*keys)(struct __pyx_obj_7brainpy_2_c_11composition_PyComposition *, int __pyx_skip_dispatch);
  PyObject *(*values)(struct __pyx_obj_7brainpy_2_c_11composition_PyComposition *, int __pyx_skip_dispatch);
  PyObject *(*items)(struct __pyx_obj_7brainpy_2_c_11composition_PyComposition *, int __pyx_skip_dispatch);
  PyObject *(*pop)(struct __pyx_obj_7brainpy_2_c_11composition_PyComposition *, PyObject *, int __pyx_skip_dispatch, struct __pyx_opt_args_7brainpy_2_c_11composition_13PyComposition_pop *__pyx_optional_args);
  __pyx_t_7brainpy_2_c_11composition_count_type (*getitem)(struct __pyx_obj_7brainpy_2_c_11composition_PyComposition *, PyObject *);
  void (*setitem)(struct __pyx_obj_7brainpy_2_c_11composition_PyComposition *, PyObject *, __pyx_t_7brainpy_2_c_11composition_count_type);
  void (*increment)(struct __pyx_obj_7brainpy_2_c_11composition_PyComposition *, PyObject *, __pyx_t_7brainpy_2_c_11composition_count_type);
  void (*add_from)(struct __pyx_obj_7brainpy_2_c_11composition_PyComposition *, struct __pyx_obj_7brainpy_2_c_11composition_PyComposition *);
  void (*subtract_from)(struct __pyx_obj_7brainpy_2_c_11composition_PyComposition *, struct __pyx_obj_7brainpy_2_c_11composition_PyComposition *);
  void (*scale_by)(struct __pyx_obj_7brainpy_2_c_11composition_PyComposition *, long);
};
static struct __pyx_vtabstruct_7brainpy_2_c_11composition_PyComposition *__pyx_vtabptr_7brainpy_2_c_11composition_PyComposition;


/* "brainpy/_c/isotopic_distribution.pxd":63
 * 
 * @freelist(100000)
 * cdef class TheoreticalPeak(object):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public double mz
 */

struct __pyx_vtabstruct_7brainpy_2_c_21isotopic_distribution_TheoreticalPeak {
  struct __pyx_obj_7brainpy_2_c_21isotopic_distribution_TheoreticalPeak *(*_create)(double, double, int);
  int (*_eq)(struct __pyx_obj_7brainpy_2_c_21isotopic_distribution_TheoreticalPeak *, struct __pyx_obj_7brainpy_2_c_21isotopic_distribution_TheoreticalPeak *, int __pyx_skip_dispatch);
  struct __pyx_obj_7brainpy_2_c_21isotopic_distribution_TheoreticalPeak *(*clone)(struct __pyx_obj_7brainpy_2_c_21isotopic_distribution_TheoreticalPeak *, int __pyx_skip_dispatch);
};
static struct __pyx_vtabstruct_7brainpy_2_c_21isotopic_distribution_TheoreticalPeak *__pyx_vtabptr_7brainpy_2_c_21isotopic_distribution_TheoreticalPeak;


/* "ms_deisotope/_c/averagine.pxd":12
 * cdef dict scale_dict(dict data, double factor)
 * 
 * cdef class Averagine(object):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public double base_mass
 */

struct __pyx_vtabstruct_12ms_deisotope_2_c_9averagine_Averagine {
  PyObject *(*scale)(struct __pyx_obj_12ms_deisotope_2_c_9averagine_Averagine *, double, int __pyx_skip_dispatch, struct __pyx_opt_args_12ms_deisotope_2_c_9averagine_9Averagine_scale *__pyx_optional_args);
  struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *(*isotopic_cluster)(struct __pyx_obj_12ms_deisotope_2_c_9averagine_Averagine *, double, int __pyx_skip_dispatch, struct __pyx_opt_args_12ms_deisotope_2_c_9averagine_9Averagine_isotopic_cluster *__pyx_optional_args);
  struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *(*_isotopic_cluster)(struct __pyx_obj_12ms_deisotope_2_c_9averagine_Averagine *, double, struct __pyx_opt_args_12ms_deisotope_2_c_9averagine_9Averagine__isotopic_cluster *__pyx_optional_args);
};
static struct __pyx_vtabstruct_12ms_deisotope_2_c_9averagine_Averagine *__pyx_vtabptr_12ms_deisotope_2_c_9averagine_Averagine;


/* "ms_deisotope/_c/averagine.pxd":23
 * 
 * @cython.final
 * cdef class TheoreticalIsotopicPattern(object):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public list peaklist
 */

struct __pyx_vtabstruct_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern {
  struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *(*_create)(PyObject *, double, double);
  struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *(*clone)(struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *, int __pyx_skip_dispatch);
  int (*_eq)(struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *, PyObject *, int __pyx_skip_dispatch);
  int (*_eq_inst)(struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *, struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *);
  struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *(*ignore_below)(struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *, int __pyx_skip_dispatch, struct __pyx_opt_args_12ms_deisotope_2_c_9averagine_26TheoreticalIsotopicPattern_ignore_below *__pyx_optional_args);
  struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *(*truncate_after)(struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *, int __pyx_skip_dispatch, struct __pyx_opt_args_12ms_deisotope_2_c_9averagine_26TheoreticalIsotopicPattern_truncate_after *__pyx_optional_args);
  struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *(*shift)(struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *, double, int __pyx_skip_dispatch);
  struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *(*scale)(struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *, PyObject *, int __pyx_skip_dispatch, struct __pyx_opt_args_12ms_deisotope_2_c_9averagine_26TheoreticalIsotopicPattern_scale *__pyx_optional_args);
  struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *(*scale_raw)(struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *, double, int __pyx_skip_dispatch);
  double (*drop_last_peak)(struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *, int __pyx_skip_dispatch);
  double (*total)(struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *, int __pyx_skip_dispatch);
  struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *(*normalize)(struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *, int __pyx_skip_dispatch);
  struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *(*_scale)(struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *, PyObject *, struct __pyx_opt_args_12ms_deisotope_2_c_9averagine_26TheoreticalIsotopicPattern__scale *__pyx_optional_args);
  struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *(*clone_shift)(struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *, double);
  struct __pyx_obj_7brainpy_2_c_21isotopic_distribution_TheoreticalPeak *(*get)(struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *, Py_ssize_t);
  size_t (*get_size)(struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *);
  double (*get_monoisotopic_mz)(struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *);
  PyObject *(*get_processed_peaks)(struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *);
  size_t (*basepeak_index)(struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *, int __pyx_skip_dispatch);
  PyObject *(*incremental_truncation)(struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *, double, int __pyx_skip_dispatch);
  struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *(*clone_drop_last)(struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *);
};
static struct __pyx_vtabstruct_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *__pyx_vtabptr_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern;


/* "ms_deisotope/_c/averagine.pxd":79
 * 
 * @cython.final
 * cdef class AveragineCache(object):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public dict backend
 */

struct __pyx_vtabstruct_12ms_deisotope_2_c_9averagine_AveragineCache {
  double (*_make_cache_key)(struct __pyx_obj_12ms_deisotope_2_c_9averagine_AveragineCache *, double);
  struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *(*has_mz_charge_pair)(struct __pyx_obj_12ms_deisotope_2_c_9averagine_AveragineCache *, double, struct __pyx_opt_args_12ms_deisotope_2_c_9averagine_14AveragineCache_has_mz_charge_pair *__pyx_optional_args);
  struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *(*isotopic_cluster)(struct __pyx_obj_12ms_deisotope_2_c_9averagine_AveragineCache *, double, int __pyx_skip_dispatch, struct __pyx_opt_args_12ms_deisotope_2_c_9averagine_14AveragineCache_isotopic_cluster *__pyx_optional_args);
};
static struct __pyx_vtabstruct_12ms_deisotope_2_c_9averagine_AveragineCache *__pyx_vtabptr_12ms_deisotope_2_c_9averagine_AveragineCache;


/* "ms_deisotope/_c/deconvoluter_base.pxd":25
 * 
 * 
 * cdef class DeconvoluterBase(object):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public bint use_subtraction
 */

struct __pyx_vtabstruct_12ms_deisotope_2_c_17deconvoluter_base_DeconvoluterBase {
  struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSet *(*between)(struct __pyx_obj_12ms_deisotope_2_c_17deconvoluter_base_DeconvoluterBase *, double, double, int __pyx_skip_dispatch);
  struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_FittedPeak *(*has_peak)(struct __pyx_obj_12ms_deisotope_2_c_17deconvoluter_base_DeconvoluterBase *, double, double, int __pyx_skip_dispatch);
  struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_FittedPeak *(*_has_peak)(struct __pyx_obj_12ms_deisotope_2_c_17deconvoluter_base_DeconvoluterBase *, double, double);
  PyObject *(*match_theoretical_isotopic_distribution)(struct __pyx_obj_12ms_deisotope_2_c_17deconvoluter_base_DeconvoluterBase *, PyObject *, int __pyx_skip_dispatch, struct __pyx_opt_args_12ms_deisotope_2_c_17deconvoluter_base_16DeconvoluterBase_match_theoretical_isotopic_distribution *__pyx_optional_args);
  PyObject *(*scale_theoretical_distribution)(struct __pyx_obj_12ms_deisotope_2_c_17deconvoluter_base_DeconvoluterBase *, struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *, PyObject *, int __pyx_skip_dispatch);
  struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitRecord *(*_evaluate_theoretical_distribution)(struct __pyx_obj_12ms_deisotope_2_c_17deconvoluter_base_DeconvoluterBase *, PyObject *, struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *, struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_FittedPeak *, int, int __pyx_skip_dispatch);
  PyObject *(*subtraction)(struct __pyx_obj_12ms_deisotope_2_c_17deconvoluter_base_DeconvoluterBase *, struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *, int __pyx_skip_dispatch, struct __pyx_opt_args_12ms_deisotope_2_c_17deconvoluter_base_16DeconvoluterBase_subtraction *__pyx_optional_args);
  PyObject *(*fit_incremental_truncation)(struct __pyx_obj_12ms_deisotope_2_c_17deconvoluter_base_DeconvoluterBase *, struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitRecord *, double, int __pyx_skip_dispatch);
  int (*_check_fit)(struct __pyx_obj_12ms_deisotope_2_c_17deconvoluter_base_DeconvoluterBase *, struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitRecord *, int __pyx_skip_dispatch);
  PyObject *(*_find_next_putative_peak)(struct __pyx_obj_12ms_deisotope_2_c_17deconvoluter_base_DeconvoluterBase *, double, int, int __pyx_skip_dispatch, struct __pyx_opt_args_12ms_deisotope_2_c_17deconvoluter_base_16DeconvoluterBase__find_next_putative_peak *__pyx_optional_args);
  PyObject *(*_find_previous_putative_peak)(struct __pyx_obj_12ms_deisotope_2_c_17deconvoluter_base_DeconvoluterBase *, double, int, int __pyx_skip_dispatch, struct __pyx_opt_args_12ms_deisotope_2_c_17deconvoluter_base_16DeconvoluterBase__find_previous_putative_peak *__pyx_optional_args);
  int (*_find_next_putative_peak_inplace)(struct __pyx_obj_12ms_deisotope_2_c_17deconvoluter_base_DeconvoluterBase *, double, int, PyObject *, struct __pyx_opt_args_12ms_deisotope_2_c_17deconvoluter_base_16DeconvoluterBase__find_next_putative_peak_inplace *__pyx_optional_args);
  int (*_find_previous_putative_peak_inplace)(struct __pyx_obj_12ms_deisotope_2_c_17deconvoluter_base_DeconvoluterBase *, double, int, PyObject *, struct __pyx_opt_args_12ms_deisotope_2_c_17deconvoluter_base_16DeconvoluterBase__find_previous_putative_peak_inplace *__pyx_optional_args);
};
static struct __pyx_vtabstruct_12ms_deisotope_2_c_17deconvoluter_base_DeconvoluterBase *__pyx_vtabptr_12ms_deisotope_2_c_17deconvoluter_base_DeconvoluterBase;


/* "ms_deisotope/_c/deconvoluter_base.pxd":57
 * 
 * 
 * cdef class AveragineDeconvoluterBase(DeconvoluterBase):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public AveragineCache averagine
 */

struct __pyx_vtabstruct_12ms_deisotope_2_c_17deconvoluter_base_AveragineDeconvoluterBase {
  struct __pyx_vtabstruct_12ms_deisotope_2_c_17deconvoluter_base_DeconvoluterBase __pyx_base;
  struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitRecord *(*fit_theoretical_distribution)(struct __pyx_obj_12ms_deisotope_2_c_17deconvoluter_base_AveragineDeconvoluterBase *, struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_FittedPeak *, double, int, int __pyx_skip_dispatch, struct __pyx_opt_args_12ms_deisotope_2_c_17deconvoluter_base_25AveragineDeconvoluterBase_fit_theoretical_distribution *__pyx_optional_args);
  PyObject *(*_fit_peaks_at_charges)(struct __pyx_obj_12ms_deisotope_2_c_17deconvoluter_base_AveragineDeconvoluterBase *, PyObject *, double, int __pyx_skip_dispatch, struct __pyx_opt_args_12ms_deisotope_2_c_17deconvoluter_base_25AveragineDeconvoluterBase__fit_peaks_at_charges *__pyx_optional_args);
};
static struct __pyx_vtabstruct_12ms_deisotope_2_c_17deconvoluter_base_AveragineDeconvoluterBase *__pyx_vtabptr_12ms_deisotope_2_c_17deconvoluter_base_AveragineDeconvoluterBase;


/* "ms_deisotope/_c/deconvoluter_base.pxd":69
 * 
 * 
 * cdef class MultiAveragineDeconvoluterBase(DeconvoluterBase):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public list averagines
 */

struct __pyx_vtabstruct_12ms_deisotope_2_c_17deconvoluter_base_MultiAveragineDeconvoluterBase {
  struct __pyx_vtabstruct_12ms_deisotope_2_c_17deconvoluter_base_DeconvoluterBase __pyx_base;
  struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitRecord *(*fit_theoretical_distribution)(struct __pyx_obj_12ms_deisotope_2_c_17deconvoluter_base_MultiAveragineDeconvoluterBase *, struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_FittedPeak *, double, int, struct __pyx_obj_12ms_deisotope_2_c_9averagine_AveragineCache *, int __pyx_skip_dispatch, struct __pyx_opt_args_12ms_deisotope_2_c_17deconvoluter_base_30MultiAveragineDeconvoluterBase_fit_theoretical_distribution *__pyx_optional_args);
  PyObject *(*_fit_peaks_at_charges)(struct __pyx_obj_12ms_deisotope_2_c_17deconvoluter_base_MultiAveragineDeconvoluterBase *, PyObject *, double, int __pyx_skip_dispatch, struct __pyx_opt_args_12ms_deisotope_2_c_17deconvoluter_base_30MultiAveragineDeconvoluterBase__fit_peaks_at_charges *__pyx_optional_args);
};
static struct __pyx_vtabstruct_12ms_deisotope_2_c_17deconvoluter_base_MultiAveragineDeconvoluterBase *__pyx_vtabptr_12ms_deisotope_2_c_17deconvoluter_base_MultiAveragineDeconvoluterBase;


/* "ms_deisotope/_c/deconvoluter_base.pxd":91
 * 
 * 
 * cdef class ChargeIterator(object):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public int lower
 */

struct __pyx_vtabstruct_12ms_deisotope_2_c_17deconvoluter_base_ChargeIterator {
  struct __pyx_obj_12ms_deisotope_2_c_17deconvoluter_base_ChargeIterator *(*_create)(int, int);
  struct __pyx_obj_12ms_deisotope_2_c_17deconvoluter_base_ChargeIterator *(*from_tuple)(PyObject *);
  struct __pyx_obj_12ms_deisotope_2_c_17deconvoluter_base_ChargeIterator *(*from_quickcharge)(PyObject *, struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSet *, struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_FittedPeak *);
  PyObject *(*sequence_from_quickcharge)(struct __pyx_obj_12ms_deisotope_2_c_17deconvoluter_base_ChargeIterator *, struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSet *, struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_FittedPeak *, int __pyx_skip_dispatch);
  PyObject *(*make_sequence)(struct __pyx_obj_12ms_deisotope_2_c_17deconvoluter_base_ChargeIterator *, int __pyx_skip_dispatch);
  void (*release_sequence)(struct __pyx_obj_12ms_deisotope_2_c_17deconvoluter_base_ChargeIterator *);
  void (*set_bounds)(struct __pyx_obj_12ms_deisotope_2_c_17deconvoluter_base_ChargeIterator *, int, int);
  int (*has_more)(struct __pyx_obj_12ms_deisotope_2_c_17deconvoluter_base_ChargeIterator *, int __pyx_skip_dispatch);
  PyObject *(*reset)(struct __pyx_obj_12ms_deisotope_2_c_17deconvoluter_base_ChargeIterator *, int __pyx_skip_dispatch);
  int (*get_next_value)(struct __pyx_obj_12ms_deisotope_2_c_17deconvoluter_base_ChargeIterator *, int __pyx_skip_dispatch);
  size_t (*get_size)(struct __pyx_obj_12ms_deisotope_2_c_17deconvoluter_base_ChargeIterator *);
};
static struct __pyx_vtabstruct_12ms_deisotope_2_c_17deconvoluter_base_ChargeIterator *__pyx_vtabptr_12ms_deisotope_2_c_17deconvoluter_base_ChargeIterator;


/* "ms_deisotope/_c/scoring.pxd":16
 * 
 * 
 * cdef class IsotopicFitRecord(object):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public FittedPeak seed_peak
 */

struct __pyx_vtabstruct_12ms_deisotope_2_c_7scoring_IsotopicFitRecord {
  struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitRecord *(*_create)(struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_FittedPeak *, double, int, struct __pyx_obj_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern *, PyObject *, struct __pyx_opt_args_12ms_deisotope_2_c_7scoring_17IsotopicFitRecord__create *__pyx_optional_args);
  int (*_eq)(struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitRecord *, struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitRecord *, int __pyx_skip_dispatch);
  int (*_ne)(struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitRecord *, struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitRecord *, int __pyx_skip_dispatch);
  int (*_lt)(struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitRecord *, struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitRecord *, int __pyx_skip_dispatch);
  int (*_gt)(struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitRecord *, struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitRecord *, int __pyx_skip_dispatch);
};
static struct __pyx_vtabstruct_12ms_deisotope_2_c_7scoring_IsotopicFitRecord *__pyx_vtabptr_12ms_deisotope_2_c_7scoring_IsotopicFitRecord;


/* "ms_deisotope/_c/scoring.pxd":38
 * 
 * 
 * cdef class FitSelectorBase(object):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public double minimum_score
 */

struct __pyx_vtabstruct_12ms_deisotope_2_c_7scoring_FitSelectorBase {
  struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitRecord *(*best)(struct __pyx_obj_12ms_deisotope_2_c_7scoring_FitSelectorBase *, PyObject *, int __pyx_skip_dispatch);
  struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitRecord *(*_best_from_set)(struct __pyx_obj_12ms_deisotope_2_c_7scoring_FitSelectorBase *, PyObject *);
  int (*reject)(struct __pyx_obj_12ms_deisotope_2_c_7scoring_FitSelectorBase *, struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitRecord *, int __pyx_skip_dispatch);
  int (*reject_score)(struct __pyx_obj_12ms_deisotope_2_c_7scoring_FitSelectorBase *, double, int __pyx_skip_dispatch);
  int (*is_maximizing)(struct __pyx_obj_12ms_deisotope_2_c_7scoring_FitSelectorBase *, int __pyx_skip_dispatch);
};
static struct __pyx_vtabstruct_12ms_deisotope_2_c_7scoring_FitSelectorBase *__pyx_vtabptr_12ms_deisotope_2_c_7scoring_FitSelectorBase;


/* "ms_deisotope/_c/scoring.pxd":50
 * 
 * 
 * cdef class IsotopicFitterBase(object):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public FitSelectorBase select
 */

struct __pyx_vtabstruct_12ms_deisotope_2_c_7scoring_IsotopicFitterBase {
  double (*_evaluate)(struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitterBase *, struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSet *, PyObject *, PyObject *, int __pyx_skip_dispatch);
  int (*reject)(struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitterBase *, struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitRecord *, int __pyx_skip_dispatch);
  int (*reject_score)(struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitterBase *, double, int __pyx_skip_dispatch);
  int (*is_maximizing)(struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitterBase *, int __pyx_skip_dispatch);
  struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitterBase *(*_configure)(struct __pyx_obj_12ms_deisotope_2_c_7scoring_IsotopicFitterBase *, struct __pyx_obj_12ms_deisotope_2_c_17deconvoluter_base_DeconvoluterBase *, PyObject *, int __pyx_skip_dispatch);
};
static struct __pyx_vtabstruct_12ms_deisotope_2_c_7scoring_IsotopicFitterBase *__pyx_vtabptr_12ms_deisotope_2_c_7scoring_IsotopicFitterBase;


/* "ms_deisotope/_c/scoring.pxd":62
 * 
 * 
 * cdef class LeastSquaresFitter(IsotopicFitterBase):             # <<<<<<<<<<<<<<
 *     pass
 * 
 */

struct __pyx_vtabstruct_12ms_deisotope_2_c_7scoring_LeastSquaresFitter {
  struct __pyx_vtabstruct_12ms_deisotope_2_c_7scoring_IsotopicFitterBase __pyx_base;
};
static struct __pyx_vtabstruct_12ms_deisotope_2_c_7scoring_LeastSquaresFitter *__pyx_vtabptr_12ms_deisotope_2_c_7scoring_LeastSquaresFitter;


/* "ms_deisotope/_c/scoring.pxd":66
 * 
 * 
 * cdef class GTestFitter(IsotopicFitterBase):             # <<<<<<<<<<<<<<
 *     pass
 * 
 */

struct __pyx_vtabstruct_12ms_deisotope_2_c_7scoring_GTestFitter {
  struct __pyx_vtabstruct_12ms_deisotope_2_c_7scoring_IsotopicFitterBase __pyx_base;
};
static struct __pyx_vtabstruct_12ms_deisotope_2_c_7scoring_GTestFitter *__pyx_vtabptr_12ms_deisotope_2_c_7scoring_GTestFitter;


/* "ms_deisotope/_c/scoring.pxd":69
 *     pass
 * 
 * cdef class ScaledGTestFitter(IsotopicFitterBase):             # <<<<<<<<<<<<<<
 *     pass
 * 
 */

struct __pyx_vtabstruct_12ms_deisotope_2_c_7scoring_ScaledGTestFitter {
  struct __pyx_vtabstruct_12ms_deisotope_2_c_7scoring_IsotopicFitterBase __pyx_base;
};
static struct __pyx_vtabstruct_12ms_deisotope_2_c_7scoring_ScaledGTestFitter *__pyx_vtabptr_12ms_deisotope_2_c_7scoring_ScaledGTestFitter;


/* "ms_deisotope/_c/scoring.pxd":72
 *     pass
 * 
 * cdef class MSDeconVFitter(IsotopicFitterBase):             # <<<<<<<<<<<<<<
 *     cdef public double mass_error_tolerance
 * 
 */

struct __pyx_vtabstruct_12ms_deisotope_2_c_7scoring_MSDeconVFitter {
  struct __pyx_vtabstruct_12ms_deisotope_2_c_7scoring_IsotopicFitterBase __pyx_base;
  double (*score_peak)(struct __pyx_obj_12ms_deisotope_2_c_7scoring_MSDeconVFitter *, struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_FittedPeak *, struct __pyx_obj_7brainpy_2_c_21isotopic_distribution_TheoreticalPeak *, struct __pyx_opt_args_12ms_deisotope_2_c_7scoring_14MSDeconVFitter_score_peak *__pyx_optional_args);
};
static struct __pyx_vtabstruct_12ms_deisotope_2_c_7scoring_MSDeconVFitter *__pyx_vtabptr_12ms_deisotope_2_c_7scoring_MSDeconVFitter;


/* "ms_deisotope/_c/scoring.pxd":78
 * 
 * 
 * cdef class PenalizedMSDeconVFitter(IsotopicFitterBase):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public double mass_error_tolerance
 */

struct __pyx_vtabstruct_12ms_deisotope_2_c_7scoring_PenalizedMSDeconVFitter {
  struct __pyx_vtabstruct_12ms_deisotope_2_c_7scoring_IsotopicFitterBase __pyx_base;
};
static struct __pyx_vtabstruct_12ms_deisotope_2_c_7scoring_PenalizedMSDeconVFitter *__pyx_vtabptr_12ms_deisotope_2_c_7scoring_PenalizedMSDeconVFitter;


/* "ms_deisotope/_c/scoring.pxd":84
 * 
 * 
 * cdef class FunctionScorer(IsotopicFitterBase):             # <<<<<<<<<<<<<<
 *     cdef:
 *         object function
 */

struct __pyx_vtabstruct_12ms_deisotope_2_c_7scoring_FunctionScorer {
  struct __pyx_vtabstruct_12ms_deisotope_2_c_7scoring_IsotopicFitterBase __pyx_base;
};
static struct __pyx_vtabstruct_12ms_deisotope_2_c_7scoring_FunctionScorer *__pyx_vtabptr_12ms_deisotope_2_c_7scoring_FunctionScorer;


/* "ms_deisotope/_c/scoring.pxd":89
 * 
 * 
 * cdef class InterferenceDetection(object):             # <<<<<<<<<<<<<<
 *     cdef public PeakSet peaklist
 * 
 */

struct __pyx_vtabstruct_12ms_deisotope_2_c_7scoring_InterferenceDetection {
  double (*detect_interference)(struct __pyx_obj_12ms_deisotope_2_c_7scoring_InterferenceDetection *, PyObject *, struct __pyx_opt_args_12ms_deisotope_2_c_7scoring_21InterferenceDetection_detect_interference *__pyx_optional_args);
};
static struct __pyx_vtabstruct_12ms_deisotope_2_c_7scoring_InterferenceDetection *__pyx_vtabptr_12ms_deisotope_2_c_7scoring_InterferenceDetection;


/* "ms_deisotope/_c/scoring.pxd":95
 * 
 * 
 * cdef class DistinctPatternFitter(IsotopicFitterBase):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public InterferenceDetection interference_detector
 */

struct __pyx_vtabstruct_12ms_deisotope_2_c_7scoring_DistinctPatternFitter {
  struct __pyx_vtabstruct_12ms_deisotope_2_c_7scoring_IsotopicFitterBase __pyx_base;
};
static struct __pyx_vtabstruct_12ms_deisotope_2_c_7scoring_DistinctPatternFitter *__pyx_vtabptr_12ms_deisotope_2_c_7scoring_DistinctPatternFitter;


/* "ms_deisotope/_c/scoring.pxd":102
 *         public double domain_scale
 * 
 * cdef class ScaledPenalizedMSDeconvFitter(IsotopicFitterBase):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public double scale_factor
 */

struct __pyx_vtabstruct_12ms_deisotope_2_c_7scoring_ScaledPenalizedMSDeconvFitter {
  struct __pyx_vtabstruct_12ms_deisotope_2_c_7scoring_IsotopicFitterBase __pyx_base;
  double (*_calculate_scale_factor)(struct __pyx_obj_12ms_deisotope_2_c_7scoring_ScaledPenalizedMSDeconvFitter *, struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSet *, int __pyx_skip_dispatch);
  void (*scale_fitted_peaks)(struct __pyx_obj_12ms_deisotope_2_c_7scoring_ScaledPenalizedMSDeconvFitter *, PyObject *, double);
  void (*scale_theoretical_peaks)(struct __pyx_obj_12ms_deisotope_2_c_7scoring_ScaledPenalizedMSDeconvFitter *, PyObject *, double);
};
static struct __pyx_vtabstruct_12ms_deisotope_2_c_7scoring_ScaledPenalizedMSDeconvFitter *__pyx_vtabptr_12ms_deisotope_2_c_7scoring_ScaledPenalizedMSDeconvFitter;


/* "ms_deisotope/_c/scoring.pxd":112
 * 
 * 
 * cdef class DotProductFitter(IsotopicFitterBase):             # <<<<<<<<<<<<<<
 *     pass
 */

struct __pyx_vtabstruct_12ms_deisotope_2_c_7scoring_DotProductFitter {
  struct __pyx_vtabstruct_12ms_deisotope_2_c_7scoring_IsotopicFitterBase __pyx_base;
};
static struct __pyx_vtabstruct_12ms_deisotope_2_c_7scoring_DotProductFitter *__pyx_vtabptr_12ms_deisotope_2_c_7scoring_DotProductFitter;


/* "ms_deisotope/_c/peak_set.pxd":5
 * 
 * 
 * cdef class _Index:             # <<<<<<<<<<<<<<
 *     cdef:
 *         public size_t neutral_mass
 */

struct __pyx_vtabstruct_12ms_deisotope_2_c_8peak_set__Index {
  struct __pyx_obj_12ms_deisotope_2_c_8peak_set__Index *(*_create)(size_t, size_t);
};
static struct __pyx_vtabstruct_12ms_deisotope_2_c_8peak_set__Index *__pyx_vtabptr_12ms_deisotope_2_c_8peak_set__Index;


/* "ms_deisotope/_c/peak_set.pxd":14
 * 
 * 
 * cdef class EnvelopePair:             # <<<<<<<<<<<<<<
 *     cdef:
 *         public double mz
 */

struct __pyx_vtabstruct_12ms_deisotope_2_c_8peak_set_EnvelopePair {
  int (*_eq)(struct __pyx_obj_12ms_deisotope_2_c_8peak_set_EnvelopePair *, struct __pyx_obj_12ms_deisotope_2_c_8peak_set_EnvelopePair *, int __pyx_skip_dispatch);
  struct __pyx_obj_12ms_deisotope_2_c_8peak_set_EnvelopePair *(*_create)(double, double);
};
static struct __pyx_vtabstruct_12ms_deisotope_2_c_8peak_set_EnvelopePair *__pyx_vtabptr_12ms_deisotope_2_c_8peak_set_EnvelopePair;


/* "ms_deisotope/_c/peak_set.pxd":25
 * 
 * 
 * cdef class Envelope:             # <<<<<<<<<<<<<<
 *     cdef public tuple pairs
 * 
 */

struct __pyx_vtabstruct_12ms_deisotope_2_c_8peak_set_Envelope {
  size_t (*get_size)(struct __pyx_obj_12ms_deisotope_2_c_8peak_set_Envelope *);
  struct __pyx_obj_12ms_deisotope_2_c_8peak_set_EnvelopePair *(*getitem)(struct __pyx_obj_12ms_deisotope_2_c_8peak_set_Envelope *, size_t);
  int (*_eq)(struct __pyx_obj_12ms_deisotope_2_c_8peak_set_Envelope *, struct __pyx_obj_12ms_deisotope_2_c_8peak_set_Envelope *, int __pyx_skip_dispatch);
  struct __pyx_obj_12ms_deisotope_2_c_8peak_set_Envelope *(*clone)(struct __pyx_obj_12ms_deisotope_2_c_8peak_set_Envelope *, int __pyx_skip_dispatch);
  struct __pyx_obj_12ms_deisotope_2_c_8peak_set_Envelope *(*_create)(PyObject *);
};
static struct __pyx_vtabstruct_12ms_deisotope_2_c_8peak_set_Envelope *__pyx_vtabptr_12ms_deisotope_2_c_8peak_set_Envelope;


/* "ms_deisotope/_c/peak_set.pxd":40
 * 
 * 
 * cdef class DeconvolutedPeak(PeakBase):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public double neutral_mass
 */

struct __pyx_vtabstruct_12ms_deisotope_2_c_8peak_set_DeconvolutedPeak {
  struct __pyx_vtabstruct_14ms_peak_picker_2_c_8peak_set_PeakBase __pyx_base;
  int (*_eq)(struct __pyx_obj_12ms_deisotope_2_c_8peak_set_DeconvolutedPeak *, struct __pyx_obj_12ms_deisotope_2_c_8peak_set_DeconvolutedPeak *, int __pyx_skip_dispatch);
  struct __pyx_obj_12ms_deisotope_2_c_8peak_set_DeconvolutedPeak *(*_create_simple)(double, double, int, double, double, struct __pyx_obj_12ms_deisotope_2_c_8peak_set_Envelope *);
};
static struct __pyx_vtabstruct_12ms_deisotope_2_c_8peak_set_DeconvolutedPeak *__pyx_vtabptr_12ms_deisotope_2_c_8peak_set_DeconvolutedPeak;


/* "ms_deisotope/_c/peak_set.pxd":66
 * 
 * 
 * cdef class DeconvolutedPeakSolution(DeconvolutedPeak):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public object solution
 */

struct __pyx_vtabstruct_12ms_deisotope_2_c_8peak_set_DeconvolutedPeakSolution {
  struct __pyx_vtabstruct_12ms_deisotope_2_c_8peak_set_DeconvolutedPeak __pyx_base;
};
static struct __pyx_vtabstruct_12ms_deisotope_2_c_8peak_set_DeconvolutedPeakSolution *__pyx_vtabptr_12ms_deisotope_2_c_8peak_set_DeconvolutedPeakSolution;


/* "ms_deisotope/_c/peak_set.pxd":70
 *         public object solution
 * 
 * cdef class DeconvolutedPeakSet(object):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public tuple peaks
 */

struct __pyx_vtabstruct_12ms_deisotope_2_c_8peak_set_DeconvolutedPeakSet {
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  struct __pyx_obj_12ms_deisotope_2_c_8peak_set_DeconvolutedPeak *(*_get_nearest_peak)(struct __pyx_obj_12ms_deisotope_2_c_8peak_set_DeconvolutedPeakSet *, double, double *);
  size_t (*get_size)(struct __pyx_obj_12ms_deisotope_2_c_8peak_set_DeconvolutedPeakSet *);
  struct __pyx_obj_12ms_deisotope_2_c_8peak_set_DeconvolutedPeak *(*getitem)(struct __pyx_obj_12ms_deisotope_2_c_8peak_set_DeconvolutedPeakSet *, size_t);
  PyObject *(*getslice)(struct __pyx_obj_12ms_deisotope_2_c_8peak_set_DeconvolutedPeakSet *, size_t, size_t);
};
static struct __pyx_vtabstruct_12ms_deisotope_2_c_8peak_set_DeconvolutedPeakSet *__pyx_vtabptr_12ms_deisotope_2_c_8peak_set_DeconvolutedPeakSet;


/* "ms_deisotope/_c/peak_set.pxd":99
 * 
 * 
 * cdef class DeconvolutedPeakSetIndexed(DeconvolutedPeakSet):             # <<<<<<<<<<<<<<
 *     cdef:
 *         double* neutral_mass_array
 */

struct __pyx_vtabstruct_12ms_deisotope_2_c_8peak_set_DeconvolutedPeakSetIndexed {
  struct __pyx_vtabstruct_12ms_deisotope_2_c_8peak_set_DeconvolutedPeakSet __pyx_base;
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  int (*_interval_for)(struct __pyx_obj_12ms_deisotope_2_c_8peak_set_DeconvolutedPeakSetIndexed *, double, double, size_t *, size_t *);
};
static struct __pyx_vtabstruct_12ms_deisotope_2_c_8peak_set_DeconvolutedPeakSetIndexed *__pyx_vtabptr_12ms_deisotope_2_c_8peak_set_DeconvolutedPeakSetIndexed;


/* "ms_deisotope/_c/similarity_methods.pyx":43
 * @cython.freelist(10000)
 * @cython.final
 * cdef class PeakMatch(object):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public PeakBase peak_a
 */

struct __pyx_vtabstruct_12ms_deisotope_2_c_18similarity_methods_PeakMatch {
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  int (*_gt)(struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_PeakMatch *, struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_PeakMatch *, int __pyx_skip_dispatch);
  int (*_eq)(struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_PeakMatch *, struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_PeakMatch *, int __pyx_skip_dispatch);
  struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_PeakMatch *(*_create)(struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakBase *, struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakBase *, struct __pyx_opt_args_12ms_deisotope_2_c_18similarity_methods_9PeakMatch__create *__pyx_optional_args);
};
static struct __pyx_vtabstruct_12ms_deisotope_2_c_18similarity_methods_PeakMatch *__pyx_vtabptr_12ms_deisotope_2_c_18similarity_methods_PeakMatch;
static int __pyx_f_12ms_deisotope_2_c_18similarity_methods_9PeakMatch__lt(struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_PeakMatch *, struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_PeakMatch *, int __pyx_skip_dispatch);
static int __pyx_f_12ms_deisotope_2_c_18similarity_methods_9PeakMatch__gt(struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_PeakMatch *, struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_PeakMatch *, int __pyx_skip_dispatch);
static int __pyx_f_12ms_deisotope_2_c_18similarity_methods_9PeakMatch__eq(struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_PeakMatch *, struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_PeakMatch *, int __pyx_skip_dispatch);
static struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_PeakMatch *__pyx_f_12ms_deisotope_2_c_18similarity_methods_9PeakMatch__create(struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakBase *, struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakBase *, struct __pyx_opt_args_12ms_deisotope_2_c_18similarity_methods_9PeakMatch__create *__pyx_optional_args);


/* "ms_deisotope/_c/similarity_methods.pyx":352
 * 
 * 
 * cdef class SpectrumAlignment(object):             # <<<<<<<<<<<<<<
 *     cdef:
 *         public list peak_pairs
 */

struct __pyx_vtabstruct_12ms_deisotope_2_c_18similarity_methods_SpectrumAlignment {
  PyObject *(*_determine_peak_type)(struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_SpectrumAlignment *, int __pyx_skip_dispatch);
  PyObject *(*align)(struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_SpectrumAlignment *, int __pyx_skip_dispatch, struct __pyx_opt_args_12ms_deisotope_2_c_18similarity_methods_17SpectrumAlignment_align *__pyx_optional_args);
  PyObject *(*_calculate_score)(struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_SpectrumAlignment *, int __pyx_skip_dispatch);
};
static struct __pyx_vtabstruct_12ms_deisotope_2_c_18similarity_methods_SpectrumAlignment *__pyx_vtabptr_12ms_deisotope_2_c_18similarity_methods_SpectrumAlignment;

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/* PyErrExceptionMatches.proto */
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#define __Pyx_PyErr_ExceptionMatches(err) __Pyx_PyErr_ExceptionMatchesInState(__pyx_tstate, err)
static CYTHON_INLINE int __Pyx_PyErr_ExceptionMatchesInState(PyThreadState* tstate, PyObject* err);
#else
#define __Pyx_PyErr_ExceptionMatches(err)  PyErr_ExceptionMatches(err)
#endif

/* GetAttr.proto */
static CYTHON_INLINE PyObject *__Pyx_GetAttr(PyObject *, PyObject *);

/* GetAttr3.proto */
static CYTHON_INLINE PyObject *__Pyx_GetAttr3(PyObject *, PyObject *, PyObject *);

/* PyDictVersioning.proto */
#if CYTHON_USE_DICT_VERSIONS && CYTHON_USE_TYPE_SLOTS
#define __PYX_DICT_VERSION_INIT  ((PY_UINT64_T) -1)
#define __PYX_GET_DICT_VERSION(dict)  (((PyDictObject*)(dict))->ma_version_tag)
#define __PYX_UPDATE_DICT_CACHE(dict, value, cache_var, version_var)\
    (version_var) = __PYX_GET_DICT_VERSION(dict);\
    (cache_var) = (value);
#define __PYX_PY_DICT_LOOKUP_IF_MODIFIED(VAR, DICT, LOOKUP) {\
    static PY_UINT64_T __pyx_dict_version = 0;\
    static PyObject *__pyx_dict_cached_value = NULL;\
    if (likely(__PYX_GET_DICT_VERSION(DICT) == __pyx_dict_version)) {\
        (VAR) = __pyx_dict_cached_value;\
    } else {\
        (VAR) = __pyx_dict_cached_value = (LOOKUP);\
        __pyx_dict_version = __PYX_GET_DICT_VERSION(DICT);\
    }\
}
static CYTHON_INLINE PY_UINT64_T __Pyx_get_tp_dict_version(PyObject *obj);
static CYTHON_INLINE PY_UINT64_T __Pyx_get_object_dict_version(PyObject *obj);
static CYTHON_INLINE int __Pyx_object_dict_version_matches(PyObject* obj, PY_UINT64_T tp_dict_version, PY_UINT64_T obj_dict_version);
#else
#define __PYX_GET_DICT_VERSION(dict)  (0)
#define __PYX_UPDATE_DICT_CACHE(dict, value, cache_var, version_var)
#define __PYX_PY_DICT_LOOKUP_IF_MODIFIED(VAR, DICT, LOOKUP)  (VAR) = (LOOKUP);
#endif

/* GetModuleGlobalName.proto */
#if CYTHON_USE_DICT_VERSIONS
#define __Pyx_GetModuleGlobalName(var, name)  {\
    static PY_UINT64_T __pyx_dict_version = 0;\
    static PyObject *__pyx_dict_cached_value = NULL;\
    (var) = (likely(__pyx_dict_version == __PYX_GET_DICT_VERSION(__pyx_d))) ?\
        (likely(__pyx_dict_cached_value) ? __Pyx_NewRef(__pyx_dict_cached_value) : __Pyx_GetBuiltinName(name)) :\
        __Pyx__GetModuleGlobalName(name, &__pyx_dict_version, &__pyx_dict_cached_value);\
}
#define __Pyx_GetModuleGlobalNameUncached(var, name)  {\
    PY_UINT64_T __pyx_dict_version;\
    PyObject *__pyx_dict_cached_value;\
    (var) = __Pyx__GetModuleGlobalName(name, &__pyx_dict_version, &__pyx_dict_cached_value);\
}
static PyObject *__Pyx__GetModuleGlobalName(PyObject *name, PY_UINT64_T *dict_version, PyObject **dict_cached_value);
#else
#define __Pyx_GetModuleGlobalName(var, name)  (var) = __Pyx__GetModuleGlobalName(name)
#define __Pyx_GetModuleGlobalNameUncached(var, name)  (var) = __Pyx__GetModuleGlobalName(name)
static CYTHON_INLINE PyObject *__Pyx__GetModuleGlobalName(PyObject *name);
#endif

/* PyDictContains.proto */
static CYTHON_INLINE int __Pyx_PyDict_ContainsTF(PyObject* item, PyObject* dict, int eq) {
    int result = PyDict_Contains(dict, item);
    return unlikely(result < 0) ? result : (result == (eq == Py_EQ));
}

/* DictGetItem.proto */
#if PY_MAJOR_VERSION >= 3 && !CYTHON_COMPILING_IN_PYPY
static PyObject *__Pyx_PyDict_GetItem(PyObject *d, PyObject* key);
#define __Pyx_PyObject_Dict_GetItem(obj, name)\
    (likely(PyDict_CheckExact(obj)) ?\
     __Pyx_PyDict_GetItem(obj, name) : PyObject_GetItem(obj, name))
#else
#define __Pyx_PyDict_GetItem(d, key) PyObject_GetItem(d, key)
#define __Pyx_PyObject_Dict_GetItem(obj, name)  PyObject_GetItem(obj, name)
#endif

/* SetItemInt.proto */
#define __Pyx_SetItemInt(o, i, v, type, is_signed, to_py_func, is_list, wraparound, boundscheck)\
    (__Pyx_fits_Py_ssize_t(i, type, is_signed) ?\
    __Pyx_SetItemInt_Fast(o, (Py_ssize_t)i, v, is_list, wraparound, boundscheck) :\
    (is_list ? (PyErr_SetString(PyExc_IndexError, "list assignment index out of range"), -1) :\
               __Pyx_SetItemInt_Generic(o, to_py_func(i), v)))
static int __Pyx_SetItemInt_Generic(PyObject *o, PyObject *j, PyObject *v);
static CYTHON_INLINE int __Pyx_SetItemInt_Fast(PyObject *o, Py_ssize_t i, PyObject *v,
                                               int is_list, int wraparound, int boundscheck);

/* IterFinish.proto */
static CYTHON_INLINE int __Pyx_IterFinish(void);

/* PyObjectCallNoArg.proto */
#if CYTHON_COMPILING_IN_CPYTHON
static CYTHON_INLINE PyObject* __Pyx_PyObject_CallNoArg(PyObject *func);
#else
#define __Pyx_PyObject_CallNoArg(func) __Pyx_PyObject_Call(func, __pyx_empty_tuple, NULL)
#endif

/* PyObjectGetMethod.proto */
static int __Pyx_PyObject_GetMethod(PyObject *obj, PyObject *name, PyObject **method);

/* PyObjectCallMethod0.proto */
static PyObject* __Pyx_PyObject_CallMethod0(PyObject* obj, PyObject* method_name);

/* RaiseNeedMoreValuesToUnpack.proto */
static CYTHON_INLINE void __Pyx_RaiseNeedMoreValuesError(Py_ssize_t index);

/* RaiseTooManyValuesToUnpack.proto */
static CYTHON_INLINE void __Pyx_RaiseTooManyValuesError(Py_ssize_t expected);

/* UnpackItemEndCheck.proto */
static int __Pyx_IternextUnpackEndCheck(PyObject *retval, Py_ssize_t expected);

/* RaiseNoneIterError.proto */
static CYTHON_INLINE void __Pyx_RaiseNoneNotIterableError(void);

/* UnpackTupleError.proto */
static void __Pyx_UnpackTupleError(PyObject *, Py_ssize_t index);

/* UnpackTuple2.proto */
#define __Pyx_unpack_tuple2(tuple, value1, value2, is_tuple, has_known_size, decref_tuple)\
    (likely(is_tuple || PyTuple_Check(tuple)) ?\
        (likely(has_known_size || PyTuple_GET_SIZE(tuple) == 2) ?\
            __Pyx_unpack_tuple2_exact(tuple, value1, value2, decref_tuple) :\
            (__Pyx_UnpackTupleError(tuple, 2), -1)) :\
        __Pyx_unpack_tuple2_generic(tuple, value1, value2, has_known_size, decref_tuple))
static CYTHON_INLINE int __Pyx_unpack_tuple2_exact(
    PyObject* tuple, PyObject** value1, PyObject** value2, int decref_tuple);
static int __Pyx_unpack_tuple2_generic(
    PyObject* tuple, PyObject** value1, PyObject** value2, int has_known_size, int decref_tuple);

/* dict_iter.proto */
static CYTHON_INLINE PyObject* __Pyx_dict_iterator(PyObject* dict, int is_dict, PyObject* method_name,
                                                   Py_ssize_t* p_orig_length, int* p_is_dict);
static CYTHON_INLINE int __Pyx_dict_iter_next(PyObject* dict_or_iter, Py_ssize_t orig_length, Py_ssize_t* ppos,
                                              PyObject** pkey, PyObject** pvalue, PyObject** pitem, int is_dict);

/* PyObjectCall2Args.proto */
static CYTHON_UNUSED PyObject* __Pyx_PyObject_Call2Args(PyObject* function, PyObject* arg1, PyObject* arg2);

/* GetItemInt.proto */
#define __Pyx_GetItemInt(o, i, type, is_signed, to_py_func, is_list, wraparound, boundscheck)\
    (__Pyx_fits_Py_ssize_t(i, type, is_signed) ?\
    __Pyx_GetItemInt_Fast(o, (Py_ssize_t)i, is_list, wraparound, boundscheck) :\
    (is_list ? (PyErr_SetString(PyExc_IndexError, "list index out of range"), (PyObject*)NULL) :\
               __Pyx_GetItemInt_Generic(o, to_py_func(i))))
#define __Pyx_GetItemInt_List(o, i, type, is_signed, to_py_func, is_list, wraparound, boundscheck)\
    (__Pyx_fits_Py_ssize_t(i, type, is_signed) ?\
    __Pyx_GetItemInt_List_Fast(o, (Py_ssize_t)i, wraparound, boundscheck) :\
    (PyErr_SetString(PyExc_IndexError, "list index out of range"), (PyObject*)NULL))
static CYTHON_INLINE PyObject *__Pyx_GetItemInt_List_Fast(PyObject *o, Py_ssize_t i,
                                                              int wraparound, int boundscheck);
#define __Pyx_GetItemInt_Tuple(o, i, type, is_signed, to_py_func, is_list, wraparound, boundscheck)\
    (__Pyx_fits_Py_ssize_t(i, type, is_signed) ?\
    __Pyx_GetItemInt_Tuple_Fast(o, (Py_ssize_t)i, wraparound, boundscheck) :\
    (PyErr_SetString(PyExc_IndexError, "tuple index out of range"), (PyObject*)NULL))
static CYTHON_INLINE PyObject *__Pyx_GetItemInt_Tuple_Fast(PyObject *o, Py_ssize_t i,
                                                              int wraparound, int boundscheck);
static PyObject *__Pyx_GetItemInt_Generic(PyObject *o, PyObject* j);
static CYTHON_INLINE PyObject *__Pyx_GetItemInt_Fast(PyObject *o, Py_ssize_t i,
                                                     int is_list, int wraparound, int boundscheck);

/* ListAppend.proto */
#if CYTHON_USE_PYLIST_INTERNALS && CYTHON_ASSUME_SAFE_MACROS
static CYTHON_INLINE int __Pyx_PyList_Append(PyObject* list, PyObject* x) {
    PyListObject* L = (PyListObject*) list;
    Py_ssize_t len = Py_SIZE(list);
    if (likely(L->allocated > len) & likely(len > (L->allocated >> 1))) {
        Py_INCREF(x);
        PyList_SET_ITEM(list, len, x);
        Py_SIZE(list) = len+1;
        return 0;
    }
    return PyList_Append(list, x);
}
#else
#define __Pyx_PyList_Append(L,x) PyList_Append(L,x)
#endif

/* IsLittleEndian.proto */
static CYTHON_INLINE int __Pyx_Is_Little_Endian(void);

/* BufferFormatCheck.proto */
static const char* __Pyx_BufFmt_CheckString(__Pyx_BufFmt_Context* ctx, const char* ts);
static void __Pyx_BufFmt_Init(__Pyx_BufFmt_Context* ctx,
                              __Pyx_BufFmt_StackElem* stack,
                              __Pyx_TypeInfo* type);

/* BufferGetAndValidate.proto */
#define __Pyx_GetBufferAndValidate(buf, obj, dtype, flags, nd, cast, stack)\
    ((obj == Py_None || obj == NULL) ?\
    (__Pyx_ZeroBuffer(buf), 0) :\
    __Pyx__GetBufferAndValidate(buf, obj, dtype, flags, nd, cast, stack))
static int  __Pyx__GetBufferAndValidate(Py_buffer* buf, PyObject* obj,
    __Pyx_TypeInfo* dtype, int flags, int nd, int cast, __Pyx_BufFmt_StackElem* stack);
static void __Pyx_ZeroBuffer(Py_buffer* buf);
static CYTHON_INLINE void __Pyx_SafeReleaseBuffer(Py_buffer* info);
static Py_ssize_t __Pyx_minusones[] = { -1, -1, -1, -1, -1, -1, -1, -1 };
static Py_ssize_t __Pyx_zeros[] = { 0, 0, 0, 0, 0, 0, 0, 0 };

/* BufferFallbackError.proto */
static void __Pyx_RaiseBufferFallbackError(void);

#define __Pyx_BufPtrStrided1d(type, buf, i0, s0) (type)((char*)buf + i0 * s0)
/* ListExtend.proto */
static CYTHON_INLINE int __Pyx_PyList_Extend(PyObject* L, PyObject* v) {
#if CYTHON_COMPILING_IN_CPYTHON
    PyObject* none = _PyList_Extend((PyListObject*)L, v);
    if (unlikely(!none))
        return -1;
    Py_DECREF(none);
    return 0;
#else
    return PyList_SetSlice(L, PY_SSIZE_T_MAX, PY_SSIZE_T_MAX, v);
#endif
}

/* pyfrozenset_new.proto */
static CYTHON_INLINE PyObject* __Pyx_PyFrozenSet_New(PyObject* it);

/* PySetContains.proto */
static CYTHON_INLINE int __Pyx_PySet_ContainsTF(PyObject* key, PyObject* set, int eq);

/* None.proto */
static CYTHON_INLINE void __Pyx_RaiseUnboundLocalError(const char *varname);

/* Import.proto */
static PyObject *__Pyx_Import(PyObject *name, PyObject *from_list, int level);

/* ImportFrom.proto */
static PyObject* __Pyx_ImportFrom(PyObject* module, PyObject* name);

/* HasAttr.proto */
static CYTHON_INLINE int __Pyx_HasAttr(PyObject *, PyObject *);

/* GetTopmostException.proto */
#if CYTHON_USE_EXC_INFO_STACK
static _PyErr_StackItem * __Pyx_PyErr_GetTopmostException(PyThreadState *tstate);
#endif

/* SaveResetException.proto */
#if CYTHON_FAST_THREAD_STATE
#define __Pyx_ExceptionSave(type, value, tb)  __Pyx__ExceptionSave(__pyx_tstate, type, value, tb)
static CYTHON_INLINE void __Pyx__ExceptionSave(PyThreadState *tstate, PyObject **type, PyObject **value, PyObject **tb);
#define __Pyx_ExceptionReset(type, value, tb)  __Pyx__ExceptionReset(__pyx_tstate, type, value, tb)
static CYTHON_INLINE void __Pyx__ExceptionReset(PyThreadState *tstate, PyObject *type, PyObject *value, PyObject *tb);
#else
#define __Pyx_ExceptionSave(type, value, tb)   PyErr_GetExcInfo(type, value, tb)
#define __Pyx_ExceptionReset(type, value, tb)  PyErr_SetExcInfo(type, value, tb)
#endif

/* GetException.proto */
#if CYTHON_FAST_THREAD_STATE
#define __Pyx_GetException(type, value, tb)  __Pyx__GetException(__pyx_tstate, type, value, tb)
static int __Pyx__GetException(PyThreadState *tstate, PyObject **type, PyObject **value, PyObject **tb);
#else
static int __Pyx_GetException(PyObject **type, PyObject **value, PyObject **tb);
#endif

/* PyObjectSetAttrStr.proto */
#if CYTHON_USE_TYPE_SLOTS
#define __Pyx_PyObject_DelAttrStr(o,n) __Pyx_PyObject_SetAttrStr(o, n, NULL)
static CYTHON_INLINE int __Pyx_PyObject_SetAttrStr(PyObject* obj, PyObject* attr_name, PyObject* value);
#else
#define __Pyx_PyObject_DelAttrStr(o,n)   PyObject_DelAttr(o,n)
#define __Pyx_PyObject_SetAttrStr(o,n,v) PyObject_SetAttr(o,n,v)
#endif

/* ObjectGetItem.proto */
#if CYTHON_USE_TYPE_SLOTS
static CYTHON_INLINE PyObject *__Pyx_PyObject_GetItem(PyObject *obj, PyObject* key);
#else
#define __Pyx_PyObject_GetItem(obj, key)  PyObject_GetItem(obj, key)
#endif

/* IncludeStringH.proto */
#include <string.h>

/* PyObject_GenericGetAttrNoDict.proto */
#if CYTHON_USE_TYPE_SLOTS && CYTHON_USE_PYTYPE_LOOKUP && PY_VERSION_HEX < 0x03070000
static CYTHON_INLINE PyObject* __Pyx_PyObject_GenericGetAttrNoDict(PyObject* obj, PyObject* attr_name);
#else
#define __Pyx_PyObject_GenericGetAttrNoDict PyObject_GenericGetAttr
#endif

/* SetVTable.proto */
static int __Pyx_SetVtable(PyObject *dict, void *vtable);

/* SetupReduce.proto */
static int __Pyx_setup_reduce(PyObject* type_obj);

/* PyObject_GenericGetAttr.proto */
#if CYTHON_USE_TYPE_SLOTS && CYTHON_USE_PYTYPE_LOOKUP && PY_VERSION_HEX < 0x03070000
static PyObject* __Pyx_PyObject_GenericGetAttr(PyObject* obj, PyObject* attr_name);
#else
#define __Pyx_PyObject_GenericGetAttr PyObject_GenericGetAttr
#endif

/* TypeImport.proto */
#ifndef __PYX_HAVE_RT_ImportType_proto
#define __PYX_HAVE_RT_ImportType_proto
enum __Pyx_ImportType_CheckSize {
   __Pyx_ImportType_CheckSize_Error = 0,
   __Pyx_ImportType_CheckSize_Warn = 1,
   __Pyx_ImportType_CheckSize_Ignore = 2
};
static PyTypeObject *__Pyx_ImportType(PyObject* module, const char *module_name, const char *class_name, size_t size, enum __Pyx_ImportType_CheckSize check_size);
#endif

/* GetVTable.proto */
static void* __Pyx_GetVtable(PyObject *dict);

/* FetchCommonType.proto */
static PyTypeObject* __Pyx_FetchCommonType(PyTypeObject* type);

/* CythonFunction.proto */
#define __Pyx_CyFunction_USED 1
#define __Pyx_CYFUNCTION_STATICMETHOD  0x01
#define __Pyx_CYFUNCTION_CLASSMETHOD   0x02
#define __Pyx_CYFUNCTION_CCLASS        0x04
#define __Pyx_CyFunction_GetClosure(f)\
    (((__pyx_CyFunctionObject *) (f))->func_closure)
#define __Pyx_CyFunction_GetClassObj(f)\
    (((__pyx_CyFunctionObject *) (f))->func_classobj)
#define __Pyx_CyFunction_Defaults(type, f)\
    ((type *)(((__pyx_CyFunctionObject *) (f))->defaults))
#define __Pyx_CyFunction_SetDefaultsGetter(f, g)\
    ((__pyx_CyFunctionObject *) (f))->defaults_getter = (g)
typedef struct {
    PyCFunctionObject func;
#if PY_VERSION_HEX < 0x030500A0
    PyObject *func_weakreflist;
#endif
    PyObject *func_dict;
    PyObject *func_name;
    PyObject *func_qualname;
    PyObject *func_doc;
    PyObject *func_globals;
    PyObject *func_code;
    PyObject *func_closure;
    PyObject *func_classobj;
    void *defaults;
    int defaults_pyobjects;
    int flags;
    PyObject *defaults_tuple;
    PyObject *defaults_kwdict;
    PyObject *(*defaults_getter)(PyObject *);
    PyObject *func_annotations;
} __pyx_CyFunctionObject;
static PyTypeObject *__pyx_CyFunctionType = 0;
#define __Pyx_CyFunction_Check(obj)  (__Pyx_TypeCheck(obj, __pyx_CyFunctionType))
#define __Pyx_CyFunction_NewEx(ml, flags, qualname, self, module, globals, code)\
    __Pyx_CyFunction_New(__pyx_CyFunctionType, ml, flags, qualname, self, module, globals, code)
static PyObject *__Pyx_CyFunction_New(PyTypeObject *, PyMethodDef *ml,
                                      int flags, PyObject* qualname,
                                      PyObject *self,
                                      PyObject *module, PyObject *globals,
                                      PyObject* code);
static CYTHON_INLINE void *__Pyx_CyFunction_InitDefaults(PyObject *m,
                                                         size_t size,
                                                         int pyobjects);
static CYTHON_INLINE void __Pyx_CyFunction_SetDefaultsTuple(PyObject *m,
                                                            PyObject *tuple);
static CYTHON_INLINE void __Pyx_CyFunction_SetDefaultsKwDict(PyObject *m,
                                                             PyObject *dict);
static CYTHON_INLINE void __Pyx_CyFunction_SetAnnotationsDict(PyObject *m,
                                                              PyObject *dict);
static int __pyx_CyFunction_init(void);

/* FusedFunction.proto */
typedef struct {
    __pyx_CyFunctionObject func;
    PyObject *__signatures__;
    PyObject *type;
    PyObject *self;
} __pyx_FusedFunctionObject;
#define __pyx_FusedFunction_NewEx(ml, flags, qualname, self, module, globals, code)\
        __pyx_FusedFunction_New(__pyx_FusedFunctionType, ml, flags, qualname, self, module, globals, code)
static PyObject *__pyx_FusedFunction_New(PyTypeObject *type,
                                         PyMethodDef *ml, int flags,
                                         PyObject *qualname, PyObject *self,
                                         PyObject *module, PyObject *globals,
                                         PyObject *code);
static int __pyx_FusedFunction_clear(__pyx_FusedFunctionObject *self);
static PyTypeObject *__pyx_FusedFunctionType = NULL;
static int __pyx_FusedFunction_init(void);
#define __Pyx_FusedFunction_USED

/* CalculateMetaclass.proto */
static PyObject *__Pyx_CalculateMetaclass(PyTypeObject *metaclass, PyObject *bases);

/* SetNameInClass.proto */
#if CYTHON_COMPILING_IN_CPYTHON && PY_VERSION_HEX >= 0x030500A1
#define __Pyx_SetNameInClass(ns, name, value)\
    (likely(PyDict_CheckExact(ns)) ? _PyDict_SetItem_KnownHash(ns, name, value, ((PyASCIIObject *) name)->hash) : PyObject_SetItem(ns, name, value))
#elif CYTHON_COMPILING_IN_CPYTHON
#define __Pyx_SetNameInClass(ns, name, value)\
    (likely(PyDict_CheckExact(ns)) ? PyDict_SetItem(ns, name, value) : PyObject_SetItem(ns, name, value))
#else
#define __Pyx_SetNameInClass(ns, name, value)  PyObject_SetItem(ns, name, value)
#endif

/* Py3ClassCreate.proto */
static PyObject *__Pyx_Py3MetaclassPrepare(PyObject *metaclass, PyObject *bases, PyObject *name, PyObject *qualname,
                                           PyObject *mkw, PyObject *modname, PyObject *doc);
static PyObject *__Pyx_Py3ClassCreate(PyObject *metaclass, PyObject *name, PyObject *bases, PyObject *dict,
                                      PyObject *mkw, int calculate_metaclass, int allow_py2_metaclass);

/* Globals.proto */
static PyObject* __Pyx_Globals(void);

/* CLineInTraceback.proto */
#ifdef CYTHON_CLINE_IN_TRACEBACK
#define __Pyx_CLineForTraceback(tstate, c_line)  (((CYTHON_CLINE_IN_TRACEBACK)) ? c_line : 0)
#else
static int __Pyx_CLineForTraceback(PyThreadState *tstate, int c_line);
#endif

/* CodeObjectCache.proto */
typedef struct {
    PyCodeObject* code_object;
    int code_line;
} __Pyx_CodeObjectCacheEntry;
struct __Pyx_CodeObjectCache {
    int count;
    int max_count;
    __Pyx_CodeObjectCacheEntry* entries;
};
static struct __Pyx_CodeObjectCache __pyx_code_cache = {0,0,NULL};
static int __pyx_bisect_code_objects(__Pyx_CodeObjectCacheEntry* entries, int count, int code_line);
static PyCodeObject *__pyx_find_code_object(int code_line);
static void __pyx_insert_code_object(int code_line, PyCodeObject* code_object);

/* AddTraceback.proto */
static void __Pyx_AddTraceback(const char *funcname, int c_line,
                               int py_line, const char *filename);

/* CIntToPy.proto */
static CYTHON_INLINE PyObject* __Pyx_PyInt_From_enum____pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType(enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType value);

/* BufferStructDeclare.proto */
typedef struct {
  Py_ssize_t shape, strides, suboffsets;
} __Pyx_Buf_DimInfo;
typedef struct {
  size_t refcount;
  Py_buffer pybuffer;
} __Pyx_Buffer;
typedef struct {
  __Pyx_Buffer *rcbuffer;
  char *data;
  __Pyx_Buf_DimInfo diminfo[8];
} __Pyx_LocalBuf_ND;

#if PY_MAJOR_VERSION < 3
    static int __Pyx_GetBuffer(PyObject *obj, Py_buffer *view, int flags);
    static void __Pyx_ReleaseBuffer(Py_buffer *view);
#else
    #define __Pyx_GetBuffer PyObject_GetBuffer
    #define __Pyx_ReleaseBuffer PyBuffer_Release
#endif


/* CIntToPy.proto */
static CYTHON_INLINE PyObject* __Pyx_PyInt_From_long(long value);

/* None.proto */
static CYTHON_INLINE long __Pyx_pow_long(long, long);

/* CIntToPy.proto */
static CYTHON_INLINE PyObject* __Pyx_PyInt_From_int(int value);

/* RealImag.proto */
#if CYTHON_CCOMPLEX
  #ifdef __cplusplus
    #define __Pyx_CREAL(z) ((z).real())
    #define __Pyx_CIMAG(z) ((z).imag())
  #else
    #define __Pyx_CREAL(z) (__real__(z))
    #define __Pyx_CIMAG(z) (__imag__(z))
  #endif
#else
    #define __Pyx_CREAL(z) ((z).real)
    #define __Pyx_CIMAG(z) ((z).imag)
#endif
#if defined(__cplusplus) && CYTHON_CCOMPLEX\
        && (defined(_WIN32) || defined(__clang__) || (defined(__GNUC__) && (__GNUC__ >= 5 || __GNUC__ == 4 && __GNUC_MINOR__ >= 4 )) || __cplusplus >= 201103)
    #define __Pyx_SET_CREAL(z,x) ((z).real(x))
    #define __Pyx_SET_CIMAG(z,y) ((z).imag(y))
#else
    #define __Pyx_SET_CREAL(z,x) __Pyx_CREAL(z) = (x)
    #define __Pyx_SET_CIMAG(z,y) __Pyx_CIMAG(z) = (y)
#endif

/* Arithmetic.proto */
#if CYTHON_CCOMPLEX
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    #define __Pyx_c_sum_float(a, b)  ((a)+(b))
    #define __Pyx_c_diff_float(a, b) ((a)-(b))
    #define __Pyx_c_prod_float(a, b) ((a)*(b))
    #define __Pyx_c_quot_float(a, b) ((a)/(b))
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    #define __Pyx_c_is_zero_float(z) ((z)==(float)0)
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    #define __Pyx_c_is_zero_float(z) ((z)==0)
    #define __Pyx_c_conj_float(z)    (conjf(z))
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        #define __Pyx_c_abs_float(z)     (cabsf(z))
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    static CYTHON_INLINE int __Pyx_c_eq_float(__pyx_t_float_complex, __pyx_t_float_complex);
    static CYTHON_INLINE __pyx_t_float_complex __Pyx_c_sum_float(__pyx_t_float_complex, __pyx_t_float_complex);
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    static CYTHON_INLINE int __Pyx_c_is_zero_float(__pyx_t_float_complex);
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        static CYTHON_INLINE float __Pyx_c_abs_float(__pyx_t_float_complex);
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/* Arithmetic.proto */
#if CYTHON_CCOMPLEX
    #define __Pyx_c_eq_double(a, b)   ((a)==(b))
    #define __Pyx_c_sum_double(a, b)  ((a)+(b))
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    #define __Pyx_c_prod_double(a, b) ((a)*(b))
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  #ifdef __cplusplus
    #define __Pyx_c_is_zero_double(z) ((z)==(double)0)
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/* CIntToPy.proto */
static CYTHON_INLINE PyObject* __Pyx_PyInt_From_enum__NPY_TYPES(enum NPY_TYPES value);

/* CIntFromPy.proto */
static CYTHON_INLINE enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType __Pyx_PyInt_As_enum____pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType(PyObject *);

/* CIntFromPy.proto */
static CYTHON_INLINE int __Pyx_PyInt_As_int(PyObject *);

/* CIntFromPy.proto */
static CYTHON_INLINE long __Pyx_PyInt_As_long(PyObject *);

/* CIntFromPy.proto */
static CYTHON_INLINE size_t __Pyx_PyInt_As_size_t(PyObject *);

/* ImportNumPyArray.proto */
static PyObject *__pyx_numpy_ndarray = NULL;
static PyObject* __Pyx_ImportNumPyArrayTypeIfAvailable(void);

/* CIntToPy.proto */
static CYTHON_INLINE PyObject* __Pyx_PyInt_From_enum____pyx_t_12ms_deisotope_2_c_18similarity_methods_SimilarityMetrics(enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_SimilarityMetrics value);

/* FastTypeChecks.proto */
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#define __Pyx_TypeCheck(obj, type) __Pyx_IsSubtype(Py_TYPE(obj), (PyTypeObject *)type)
static CYTHON_INLINE int __Pyx_IsSubtype(PyTypeObject *a, PyTypeObject *b);
static CYTHON_INLINE int __Pyx_PyErr_GivenExceptionMatches(PyObject *err, PyObject *type);
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/* InitStrings.proto */
static int __Pyx_InitStrings(__Pyx_StringTabEntry *t);

static int __pyx_f_12ms_deisotope_2_c_18similarity_methods_9PeakMatch__lt(struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_PeakMatch *__pyx_v_self, struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_PeakMatch *__pyx_v_other, CYTHON_UNUSED int __pyx_skip_dispatch); /* proto*/
static int __pyx_f_12ms_deisotope_2_c_18similarity_methods_9PeakMatch__gt(struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_PeakMatch *__pyx_v_self, struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_PeakMatch *__pyx_v_other, CYTHON_UNUSED int __pyx_skip_dispatch); /* proto*/
static int __pyx_f_12ms_deisotope_2_c_18similarity_methods_9PeakMatch__eq(struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_PeakMatch *__pyx_v_self, struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_PeakMatch *__pyx_v_other, CYTHON_UNUSED int __pyx_skip_dispatch); /* proto*/
static struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_PeakMatch *__pyx_f_12ms_deisotope_2_c_18similarity_methods_9PeakMatch__create(struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakBase *__pyx_v_peak_a, struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakBase *__pyx_v_peak_b, struct __pyx_opt_args_12ms_deisotope_2_c_18similarity_methods_9PeakMatch__create *__pyx_optional_args); /* proto*/
static PyObject *__pyx_f_12ms_deisotope_2_c_18similarity_methods_17SpectrumAlignment__determine_peak_type(struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_SpectrumAlignment *__pyx_v_self, int __pyx_skip_dispatch); /* proto*/
static PyObject *__pyx_f_12ms_deisotope_2_c_18similarity_methods_17SpectrumAlignment_align(struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_SpectrumAlignment *__pyx_v_self, int __pyx_skip_dispatch, struct __pyx_opt_args_12ms_deisotope_2_c_18similarity_methods_17SpectrumAlignment_align *__pyx_optional_args); /* proto*/
static PyObject *__pyx_f_12ms_deisotope_2_c_18similarity_methods_17SpectrumAlignment__calculate_score(struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_SpectrumAlignment *__pyx_v_self, int __pyx_skip_dispatch); /* proto*/

/* Module declarations from 'cython' */

/* Module declarations from 'libc.math' */

/* Module declarations from 'libc.string' */

/* Module declarations from 'libc.stdlib' */

/* Module declarations from 'libc.stdio' */

/* Module declarations from 'cpython.version' */

/* Module declarations from '__builtin__' */

/* Module declarations from 'cpython.type' */
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/* Module declarations from 'cpython.object' */

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/* Module declarations from 'cpython.exc' */

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/* Module declarations from 'cpython.mem' */

/* Module declarations from 'cpython.tuple' */

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/* Module declarations from 'cpython.string' */

/* Module declarations from 'cpython.unicode' */

/* Module declarations from 'cpython.dict' */

/* Module declarations from 'cpython.instance' */

/* Module declarations from 'cpython.function' */

/* Module declarations from 'cpython.method' */

/* Module declarations from 'cpython.weakref' */

/* Module declarations from 'cpython.getargs' */

/* Module declarations from 'cpython.pythread' */

/* Module declarations from 'cpython.pystate' */

/* Module declarations from 'cpython.cobject' */

/* Module declarations from 'cpython.oldbuffer' */

/* Module declarations from 'cpython.set' */

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/* Module declarations from 'cpython.bytes' */

/* Module declarations from 'cpython.pycapsule' */

/* Module declarations from 'cpython' */

/* Module declarations from 'numpy' */

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static PyTypeObject *__pyx_ptype_5numpy_ufunc = 0;
static CYTHON_INLINE char *__pyx_f_5numpy__util_dtypestring(PyArray_Descr *, char *, char *, int *); /*proto*/

/* Module declarations from 'ms_peak_picker._c.peak_set' */
static PyTypeObject *__pyx_ptype_14ms_peak_picker_2_c_8peak_set_PeakBase = 0;
static PyTypeObject *__pyx_ptype_14ms_peak_picker_2_c_8peak_set_FittedPeak = 0;
static PyTypeObject *__pyx_ptype_14ms_peak_picker_2_c_8peak_set_PeakSet = 0;
static PyTypeObject *__pyx_ptype_14ms_peak_picker_2_c_8peak_set_PeakSetIndexed = 0;
static size_t *__pyx_vp_14ms_peak_picker_2_c_8peak_set_INTERVAL_INDEX_SIZE = 0;
#define __pyx_v_14ms_peak_picker_2_c_8peak_set_INTERVAL_INDEX_SIZE (*__pyx_vp_14ms_peak_picker_2_c_8peak_set_INTERVAL_INDEX_SIZE)

/* Module declarations from 'ms_peak_picker._c.peak_index' */
static PyTypeObject *__pyx_ptype_14ms_peak_picker_2_c_10peak_index_PeakIndex = 0;

/* Module declarations from 'brainpy._c.composition' */
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/* Module declarations from 'brainpy._c.double_vector' */

/* Module declarations from 'brainpy._c.isotopic_constants' */
static size_t *__pyx_vp_7brainpy_2_c_18isotopic_constants_DEFAULT_ISOTOPIC_CONSTANTS_SIZE = 0;
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/* Module declarations from 'brainpy._c.isotopic_distribution' */
static PyTypeObject *__pyx_ptype_7brainpy_2_c_21isotopic_distribution_TheoreticalPeak = 0;

/* Module declarations from 'ms_deisotope._c.averagine' */
static PyTypeObject *__pyx_ptype_12ms_deisotope_2_c_9averagine_Averagine = 0;
static PyTypeObject *__pyx_ptype_12ms_deisotope_2_c_9averagine_TheoreticalIsotopicPattern = 0;
static PyTypeObject *__pyx_ptype_12ms_deisotope_2_c_9averagine_AveragineCache = 0;
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/* Module declarations from 'ms_deisotope._c.deconvoluter_base' */
static PyTypeObject *__pyx_ptype_12ms_deisotope_2_c_17deconvoluter_base_DeconvoluterBase = 0;
static PyTypeObject *__pyx_ptype_12ms_deisotope_2_c_17deconvoluter_base_AveragineDeconvoluterBase = 0;
static PyTypeObject *__pyx_ptype_12ms_deisotope_2_c_17deconvoluter_base_MultiAveragineDeconvoluterBase = 0;
static PyTypeObject *__pyx_ptype_12ms_deisotope_2_c_17deconvoluter_base_ChargeIterator = 0;

/* Module declarations from 'ms_deisotope._c.scoring' */
static PyTypeObject *__pyx_ptype_12ms_deisotope_2_c_7scoring_IsotopicFitRecord = 0;
static PyTypeObject *__pyx_ptype_12ms_deisotope_2_c_7scoring_FitSelectorBase = 0;
static PyTypeObject *__pyx_ptype_12ms_deisotope_2_c_7scoring_IsotopicFitterBase = 0;
static PyTypeObject *__pyx_ptype_12ms_deisotope_2_c_7scoring_LeastSquaresFitter = 0;
static PyTypeObject *__pyx_ptype_12ms_deisotope_2_c_7scoring_GTestFitter = 0;
static PyTypeObject *__pyx_ptype_12ms_deisotope_2_c_7scoring_ScaledGTestFitter = 0;
static PyTypeObject *__pyx_ptype_12ms_deisotope_2_c_7scoring_MSDeconVFitter = 0;
static PyTypeObject *__pyx_ptype_12ms_deisotope_2_c_7scoring_PenalizedMSDeconVFitter = 0;
static PyTypeObject *__pyx_ptype_12ms_deisotope_2_c_7scoring_FunctionScorer = 0;
static PyTypeObject *__pyx_ptype_12ms_deisotope_2_c_7scoring_InterferenceDetection = 0;
static PyTypeObject *__pyx_ptype_12ms_deisotope_2_c_7scoring_DistinctPatternFitter = 0;
static PyTypeObject *__pyx_ptype_12ms_deisotope_2_c_7scoring_ScaledPenalizedMSDeconvFitter = 0;
static PyTypeObject *__pyx_ptype_12ms_deisotope_2_c_7scoring_DotProductFitter = 0;
static double *__pyx_vp_12ms_deisotope_2_c_7scoring_INFINITY = 0;
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/* Module declarations from 'ms_deisotope._c.peak_set' */
static PyTypeObject *__pyx_ptype_12ms_deisotope_2_c_8peak_set__Index = 0;
static PyTypeObject *__pyx_ptype_12ms_deisotope_2_c_8peak_set_EnvelopePair = 0;
static PyTypeObject *__pyx_ptype_12ms_deisotope_2_c_8peak_set_Envelope = 0;
static PyTypeObject *__pyx_ptype_12ms_deisotope_2_c_8peak_set_DeconvolutedPeak = 0;
static PyTypeObject *__pyx_ptype_12ms_deisotope_2_c_8peak_set_DeconvolutedPeakSolution = 0;
static PyTypeObject *__pyx_ptype_12ms_deisotope_2_c_8peak_set_DeconvolutedPeakSet = 0;
static PyTypeObject *__pyx_ptype_12ms_deisotope_2_c_8peak_set_DeconvolutedPeakSetIndexed = 0;
static size_t *__pyx_vp_12ms_deisotope_2_c_8peak_set_INTERVAL_INDEX_SIZE = 0;
#define __pyx_v_12ms_deisotope_2_c_8peak_set_INTERVAL_INDEX_SIZE (*__pyx_vp_12ms_deisotope_2_c_8peak_set_INTERVAL_INDEX_SIZE)

/* Module declarations from 'ms_deisotope._c.similarity_methods' */
static PyTypeObject *__pyx_ptype_12ms_deisotope_2_c_18similarity_methods_PeakMatch = 0;
static PyTypeObject *__pyx_ptype_12ms_deisotope_2_c_18similarity_methods_SpectrumAlignment = 0;
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static PyObject *__pyx_v_12ms_deisotope_2_c_18similarity_methods_zeros = 0;
static PyObject *__Pyx_OrderedDict = 0;
static PyObject *__Pyx_EnumBase = 0;
static PyObject *__Pyx_globals = 0;
static PyObject *__pyx_f_12ms_deisotope_2_c_18similarity_methods_convolve_peak_sets(struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSet *, struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSet *, struct __pyx_opt_args_12ms_deisotope_2_c_18similarity_methods_convolve_peak_sets *__pyx_optional_args); /*proto*/
static PyObject *__pyx_f_12ms_deisotope_2_c_18similarity_methods_convolve_deconvoluted_peak_sets(struct __pyx_obj_12ms_deisotope_2_c_8peak_set_DeconvolutedPeakSet *, struct __pyx_obj_12ms_deisotope_2_c_8peak_set_DeconvolutedPeakSet *, struct __pyx_opt_args_12ms_deisotope_2_c_18similarity_methods_convolve_deconvoluted_peak_sets *__pyx_optional_args); /*proto*/
static double __pyx_f_12ms_deisotope_2_c_18similarity_methods_convolved_dot_product(PyObject *, struct __pyx_opt_args_12ms_deisotope_2_c_18similarity_methods_convolved_dot_product *__pyx_optional_args); /*proto*/
static double __pyx_f_12ms_deisotope_2_c_18similarity_methods_convolve_peak_sets2_fitted(struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSet *, struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSet *, struct __pyx_opt_args_12ms_deisotope_2_c_18similarity_methods_convolve_peak_sets2_fitted *__pyx_optional_args); /*proto*/
static double __pyx_f_12ms_deisotope_2_c_18similarity_methods_convolve_peak_sets2_deconvoluted(struct __pyx_obj_12ms_deisotope_2_c_8peak_set_DeconvolutedPeakSet *, struct __pyx_obj_12ms_deisotope_2_c_8peak_set_DeconvolutedPeakSet *, struct __pyx_opt_args_12ms_deisotope_2_c_18similarity_methods_convolve_peak_sets2_deconvoluted *__pyx_optional_args); /*proto*/
static PyObject *__pyx_f_12ms_deisotope_2_c_18similarity_methods___pyx_unpickle_PeakMatch__set_state(struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_PeakMatch *, PyObject *); /*proto*/
static PyObject **__pyx_fuse_0__pyx_f_12ms_deisotope_2_c_18similarity_methods__make_fast_array(struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSet *); /*proto*/
static PyObject **__pyx_fuse_1__pyx_f_12ms_deisotope_2_c_18similarity_methods__make_fast_array(struct __pyx_obj_14ms_peak_picker_2_c_10peak_index_PeakIndex *); /*proto*/
static PyObject **__pyx_fuse_2__pyx_f_12ms_deisotope_2_c_18similarity_methods__make_fast_array(struct __pyx_obj_12ms_deisotope_2_c_8peak_set_DeconvolutedPeakSet *); /*proto*/
static PyObject **__pyx_fuse_3__pyx_f_12ms_deisotope_2_c_18similarity_methods__make_fast_array(PyObject *); /*proto*/
static double __pyx_fuse_0__pyx_f_12ms_deisotope_2_c_18similarity_methods_peak_set_similarity(struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSet *, struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSet *, int __pyx_skip_dispatch, struct __pyx_fuse_0__pyx_opt_args_12ms_deisotope_2_c_18similarity_methods_peak_set_similarity *__pyx_optional_args); /*proto*/
static double __pyx_fuse_1__pyx_f_12ms_deisotope_2_c_18similarity_methods_peak_set_similarity(struct __pyx_obj_14ms_peak_picker_2_c_10peak_index_PeakIndex *, struct __pyx_obj_14ms_peak_picker_2_c_10peak_index_PeakIndex *, int __pyx_skip_dispatch, struct __pyx_fuse_1__pyx_opt_args_12ms_deisotope_2_c_18similarity_methods_peak_set_similarity *__pyx_optional_args); /*proto*/
static double __pyx_fuse_2__pyx_f_12ms_deisotope_2_c_18similarity_methods_peak_set_similarity(struct __pyx_obj_12ms_deisotope_2_c_8peak_set_DeconvolutedPeakSet *, struct __pyx_obj_12ms_deisotope_2_c_8peak_set_DeconvolutedPeakSet *, int __pyx_skip_dispatch, struct __pyx_fuse_2__pyx_opt_args_12ms_deisotope_2_c_18similarity_methods_peak_set_similarity *__pyx_optional_args); /*proto*/
static double __pyx_fuse_3__pyx_f_12ms_deisotope_2_c_18similarity_methods_peak_set_similarity(PyObject *, PyObject *, int __pyx_skip_dispatch, struct __pyx_fuse_3__pyx_opt_args_12ms_deisotope_2_c_18similarity_methods_peak_set_similarity *__pyx_optional_args); /*proto*/
static PyObject *__pyx_fuse_0__pyx_f_12ms_deisotope_2_c_18similarity_methods_bin_peaks(struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSet *, struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSet *, int __pyx_skip_dispatch, struct __pyx_fuse_0__pyx_opt_args_12ms_deisotope_2_c_18similarity_methods_bin_peaks *__pyx_optional_args); /*proto*/
static PyObject *__pyx_fuse_1__pyx_f_12ms_deisotope_2_c_18similarity_methods_bin_peaks(struct __pyx_obj_14ms_peak_picker_2_c_10peak_index_PeakIndex *, struct __pyx_obj_14ms_peak_picker_2_c_10peak_index_PeakIndex *, int __pyx_skip_dispatch, struct __pyx_fuse_1__pyx_opt_args_12ms_deisotope_2_c_18similarity_methods_bin_peaks *__pyx_optional_args); /*proto*/
static PyObject *__pyx_fuse_2__pyx_f_12ms_deisotope_2_c_18similarity_methods_bin_peaks(struct __pyx_obj_12ms_deisotope_2_c_8peak_set_DeconvolutedPeakSet *, struct __pyx_obj_12ms_deisotope_2_c_8peak_set_DeconvolutedPeakSet *, int __pyx_skip_dispatch, struct __pyx_fuse_2__pyx_opt_args_12ms_deisotope_2_c_18similarity_methods_bin_peaks *__pyx_optional_args); /*proto*/
static PyObject *__pyx_fuse_3__pyx_f_12ms_deisotope_2_c_18similarity_methods_bin_peaks(PyObject *, PyObject *, int __pyx_skip_dispatch, struct __pyx_fuse_3__pyx_opt_args_12ms_deisotope_2_c_18similarity_methods_bin_peaks *__pyx_optional_args); /*proto*/
static double __pyx_fuse_0__pyx_f_12ms_deisotope_2_c_18similarity_methods_ppm_peak_set_similarity(struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSet *, struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSet *, int __pyx_skip_dispatch, struct __pyx_fuse_0__pyx_opt_args_12ms_deisotope_2_c_18similarity_methods_ppm_peak_set_similarity *__pyx_optional_args); /*proto*/
static double __pyx_fuse_1__pyx_f_12ms_deisotope_2_c_18similarity_methods_ppm_peak_set_similarity(struct __pyx_obj_14ms_peak_picker_2_c_10peak_index_PeakIndex *, struct __pyx_obj_14ms_peak_picker_2_c_10peak_index_PeakIndex *, int __pyx_skip_dispatch, struct __pyx_fuse_1__pyx_opt_args_12ms_deisotope_2_c_18similarity_methods_ppm_peak_set_similarity *__pyx_optional_args); /*proto*/
static double __pyx_fuse_2__pyx_f_12ms_deisotope_2_c_18similarity_methods_ppm_peak_set_similarity(struct __pyx_obj_12ms_deisotope_2_c_8peak_set_DeconvolutedPeakSet *, struct __pyx_obj_12ms_deisotope_2_c_8peak_set_DeconvolutedPeakSet *, int __pyx_skip_dispatch, struct __pyx_fuse_2__pyx_opt_args_12ms_deisotope_2_c_18similarity_methods_ppm_peak_set_similarity *__pyx_optional_args); /*proto*/
static double __pyx_fuse_3__pyx_f_12ms_deisotope_2_c_18similarity_methods_ppm_peak_set_similarity(PyObject *, PyObject *, int __pyx_skip_dispatch, struct __pyx_fuse_3__pyx_opt_args_12ms_deisotope_2_c_18similarity_methods_ppm_peak_set_similarity *__pyx_optional_args); /*proto*/
static struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_SpectrumAlignment *__pyx_fuse_0__pyx_f_12ms_deisotope_2_c_18similarity_methods_align_peaks(struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSet *, struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSet *, int __pyx_skip_dispatch, struct __pyx_fuse_0__pyx_opt_args_12ms_deisotope_2_c_18similarity_methods_align_peaks *__pyx_optional_args); /*proto*/
static struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_SpectrumAlignment *__pyx_fuse_1__pyx_f_12ms_deisotope_2_c_18similarity_methods_align_peaks(struct __pyx_obj_14ms_peak_picker_2_c_10peak_index_PeakIndex *, struct __pyx_obj_14ms_peak_picker_2_c_10peak_index_PeakIndex *, int __pyx_skip_dispatch, struct __pyx_fuse_1__pyx_opt_args_12ms_deisotope_2_c_18similarity_methods_align_peaks *__pyx_optional_args); /*proto*/
static struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_SpectrumAlignment *__pyx_fuse_2__pyx_f_12ms_deisotope_2_c_18similarity_methods_align_peaks(struct __pyx_obj_12ms_deisotope_2_c_8peak_set_DeconvolutedPeakSet *, struct __pyx_obj_12ms_deisotope_2_c_8peak_set_DeconvolutedPeakSet *, int __pyx_skip_dispatch, struct __pyx_fuse_2__pyx_opt_args_12ms_deisotope_2_c_18similarity_methods_align_peaks *__pyx_optional_args); /*proto*/
static struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_SpectrumAlignment *__pyx_fuse_3__pyx_f_12ms_deisotope_2_c_18similarity_methods_align_peaks(PyObject *, PyObject *, int __pyx_skip_dispatch, struct __pyx_fuse_3__pyx_opt_args_12ms_deisotope_2_c_18similarity_methods_align_peaks *__pyx_optional_args); /*proto*/
static PyObject *__pyx_f_12ms_deisotope_2_c_18similarity_methods___pyx_unpickle_SpectrumAlignment__set_state(struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_SpectrumAlignment *, PyObject *); /*proto*/
static PyObject *__pyx_unpickle___Pyx_EnumMeta__set_state(struct __pyx_obj___Pyx_EnumMeta *, PyObject *); /*proto*/
static __Pyx_TypeInfo __Pyx_TypeInfo_double = { "double", NULL, sizeof(double), { 0 }, 0, 'R', 0, 0 };
#define __Pyx_MODULE_NAME "ms_deisotope._c.similarity_methods"
extern int __pyx_module_is_main_ms_deisotope___c__similarity_methods;
int __pyx_module_is_main_ms_deisotope___c__similarity_methods = 0;

/* Implementation of 'ms_deisotope._c.similarity_methods' */
static PyObject *__pyx_builtin_IndexError;
static PyObject *__pyx_builtin_TypeError;
static PyObject *__pyx_builtin___import__;
static PyObject *__pyx_builtin_range;
static PyObject *__pyx_builtin_MemoryError;
static PyObject *__pyx_builtin_ValueError;
static PyObject *__pyx_builtin_RuntimeError;
static PyObject *__pyx_builtin_ImportError;
static const char __pyx_k_s[] = "s";
static const char __pyx_k_v[] = "v";
static const char __pyx_k__2[] = "";
static const char __pyx_k__3[] = "()";
static const char __pyx_k__4[] = "|";
static const char __pyx_k_np[] = "np";
static const char __pyx_k_cls[] = "cls";
static const char __pyx_k_dct[] = "dct";
static const char __pyx_k_doc[] = "__doc__";
static const char __pyx_k_new[] = "__new__";
static const char __pyx_k_res[] = "res";
static const char __pyx_k_s_s[] = "%s.%s";
static const char __pyx_k_str[] = "__str__";
static const char __pyx_k_args[] = "args";
static const char __pyx_k_dict[] = "__dict__";
static const char __pyx_k_enum[] = "enum";
static const char __pyx_k_init[] = "__init__";
static const char __pyx_k_main[] = "__main__";
static const char __pyx_k_name[] = "name";
static const char __pyx_k_repr[] = "__repr__";
static const char __pyx_k_self[] = "self";
static const char __pyx_k_test[] = "__test__";
static const char __pyx_k_align[] = "align";
static const char __pyx_k_class[] = "__class__";
static const char __pyx_k_numpy[] = "numpy";
static const char __pyx_k_range[] = "range";
static const char __pyx_k_s_s_d[] = "<%s.%s: %d>";
static const char __pyx_k_score[] = "score";
static const char __pyx_k_shift[] = "shift";
static const char __pyx_k_split[] = "split";
static const char __pyx_k_strip[] = "strip";
static const char __pyx_k_value[] = "value";
static const char __pyx_k_zeros[] = "zeros";
static const char __pyx_k_Fitted[] = "Fitted";
static const char __pyx_k_format[] = "format";
static const char __pyx_k_import[] = "__import__";
static const char __pyx_k_kwargs[] = "kwargs";
static const char __pyx_k_module[] = "__module__";
static const char __pyx_k_name_2[] = "__name__";
static const char __pyx_k_object[] = "object";
static const char __pyx_k_peak_a[] = "peak_a";
static const char __pyx_k_peak_b[] = "peak_b";
static const char __pyx_k_pickle[] = "pickle";
static const char __pyx_k_reduce[] = "__reduce__";
static const char __pyx_k_update[] = "update";
static const char __pyx_k_values[] = "values";
static const char __pyx_k_IntEnum[] = "IntEnum";
static const char __pyx_k_PeakSet[] = "PeakSet";
static const char __pyx_k_members[] = "__members__";
static const char __pyx_k_parents[] = "parents";
static const char __pyx_k_prepare[] = "__prepare__";
static const char __pyx_k_EnumBase[] = "EnumBase";
static const char __pyx_k_EnumType[] = "EnumType";
static const char __pyx_k_PeakType[] = "PeakType";
static const char __pyx_k_defaults[] = "defaults";
static const char __pyx_k_getstate[] = "__getstate__";
static const char __pyx_k_pyx_type[] = "__pyx_type";
static const char __pyx_k_qualname[] = "__qualname__";
static const char __pyx_k_setstate[] = "__setstate__";
static const char __pyx_k_PeakIndex[] = "PeakIndex";
static const char __pyx_k_PeakMatch[] = "PeakMatch";
static const char __pyx_k_TypeError[] = "TypeError";
static const char __pyx_k_bin_peaks[] = "bin_peaks";
static const char __pyx_k_metaclass[] = "__metaclass__";
static const char __pyx_k_precision[] = "precision";
static const char __pyx_k_pyx_state[] = "__pyx_state";
static const char __pyx_k_reduce_ex[] = "__reduce_ex__";
static const char __pyx_k_IndexError[] = "IndexError";
static const char __pyx_k_ValueError[] = "ValueError";
static const char __pyx_k_peak_set_a[] = "peak_set_a";
static const char __pyx_k_peak_set_b[] = "peak_set_b";
static const char __pyx_k_pyx_result[] = "__pyx_result";
static const char __pyx_k_pyx_vtable[] = "__pyx_vtable__";
static const char __pyx_k_signatures[] = "signatures";
static const char __pyx_k_ImportError[] = "ImportError";
static const char __pyx_k_MemoryError[] = "MemoryError";
static const char __pyx_k_OrderedDict[] = "OrderedDict";
static const char __pyx_k_PickleError[] = "PickleError";
static const char __pyx_k_align_peaks[] = "align_peaks";
static const char __pyx_k_collections[] = "collections";
static const char __pyx_k_dot_product[] = "dot_product";
static const char __pyx_k_Deconvoluted[] = "Deconvoluted";
static const char __pyx_k_Pyx_EnumBase[] = "__Pyx_EnumBase";
static const char __pyx_k_RuntimeError[] = "RuntimeError";
static const char __pyx_k_pyx_checksum[] = "__pyx_checksum";
static const char __pyx_k_stringsource[] = "stringsource";
static const char __pyx_k_reduce_cython[] = "__reduce_cython__";
static const char __pyx_k_calculate_score[] = "_calculate_score";
static const char __pyx_k_error_tolerance[] = "error_tolerance";
static const char __pyx_k_pyx_PickleError[] = "__pyx_PickleError";
static const char __pyx_k_setstate_cython[] = "__setstate_cython__";
static const char __pyx_k_SimilarityMetrics[] = "SimilarityMetrics";
static const char __pyx_k_SpectrumAlignment[] = "SpectrumAlignment";
static const char __pyx_k_Pyx_EnumBase___new[] = "__Pyx_EnumBase.__new__";
static const char __pyx_k_Pyx_EnumBase___str[] = "__Pyx_EnumBase.__str__";
static const char __pyx_k_cline_in_traceback[] = "cline_in_traceback";
static const char __pyx_k_DeconvolutedPeakSet[] = "DeconvolutedPeakSet";
static const char __pyx_k_Pyx_EnumBase___repr[] = "__Pyx_EnumBase.__repr__";
static const char __pyx_k_determine_peak_type[] = "_determine_peak_type";
static const char __pyx_k_peak_set_similarity[] = "peak_set_similarity";
static const char __pyx_k_pyx_fuse_0bin_peaks[] = "__pyx_fuse_0bin_peaks";
static const char __pyx_k_pyx_fuse_1bin_peaks[] = "__pyx_fuse_1bin_peaks";
static const char __pyx_k_pyx_fuse_2bin_peaks[] = "__pyx_fuse_2bin_peaks";
static const char __pyx_k_pyx_fuse_3bin_peaks[] = "__pyx_fuse_3bin_peaks";
static const char __pyx_k_Unknown_enum_value_s[] = "Unknown enum value: '%s'";
static const char __pyx_k_pyx_fuse_0align_peaks[] = "__pyx_fuse_0align_peaks";
static const char __pyx_k_pyx_fuse_1align_peaks[] = "__pyx_fuse_1align_peaks";
static const char __pyx_k_pyx_fuse_2align_peaks[] = "__pyx_fuse_2align_peaks";
static const char __pyx_k_pyx_fuse_3align_peaks[] = "__pyx_fuse_3align_peaks";
static const char __pyx_k_normalized_dot_product[] = "normalized_dot_product";
static const char __pyx_k_pyx_unpickle_PeakMatch[] = "__pyx_unpickle_PeakMatch";
static const char __pyx_k_ppm_peak_set_similarity[] = "ppm_peak_set_similarity";
static const char __pyx_k_ms_deisotope__c_peak_set[] = "ms_deisotope._c.peak_set";
static const char __pyx_k_ms_peak_picker__c_peak_set[] = "ms_peak_picker._c.peak_set";
static const char __pyx_k_No_matching_signature_found[] = "No matching signature found";
static const char __pyx_k_ndarray_is_not_C_contiguous[] = "ndarray is not C contiguous";
static const char __pyx_k_pyx_unpickle___Pyx_EnumMeta[] = "__pyx_unpickle___Pyx_EnumMeta";
static const char __pyx_k_ms_peak_picker__c_peak_index[] = "ms_peak_picker._c.peak_index";
static const char __pyx_k_pyx_fuse_0peak_set_similarity[] = "__pyx_fuse_0peak_set_similarity";
static const char __pyx_k_pyx_fuse_1peak_set_similarity[] = "__pyx_fuse_1peak_set_similarity";
static const char __pyx_k_pyx_fuse_2peak_set_similarity[] = "__pyx_fuse_2peak_set_similarity";
static const char __pyx_k_pyx_fuse_3peak_set_similarity[] = "__pyx_fuse_3peak_set_similarity";
static const char __pyx_k_pyx_fuse_0ppm_peak_set_similar[] = "__pyx_fuse_0ppm_peak_set_similarity";
static const char __pyx_k_pyx_fuse_1ppm_peak_set_similar[] = "__pyx_fuse_1ppm_peak_set_similarity";
static const char __pyx_k_pyx_fuse_2ppm_peak_set_similar[] = "__pyx_fuse_2ppm_peak_set_similarity";
static const char __pyx_k_pyx_fuse_3ppm_peak_set_similar[] = "__pyx_fuse_3ppm_peak_set_similarity";
static const char __pyx_k_pyx_unpickle_SpectrumAlignment[] = "__pyx_unpickle_SpectrumAlignment";
static const char __pyx_k_Cannot_handle_objects_of_type_s[] = "Cannot handle objects of type %s";
static const char __pyx_k_Peak_set_types_must_match_got_s[] = "Peak set types must match, got %s and %s";
static const char __pyx_k_numpy_core_multiarray_failed_to[] = "numpy.core.multiarray failed to import";
static const char __pyx_k_self___class_____name___self_pe[] = "{self.__class__.__name__}({self.peak_a}, {self.peak_b}, {self.score})";
static const char __pyx_k_unknown_dtype_code_in_numpy_pxd[] = "unknown dtype code in numpy.pxd (%d)";
static const char __pyx_k_Expected_at_least_d_argument_s_g[] = "Expected at least %d argument%s, got %d";
static const char __pyx_k_Format_string_allocated_too_shor[] = "Format string allocated too short, see comment in numpy.pxd";
static const char __pyx_k_Function_call_with_ambiguous_arg[] = "Function call with ambiguous argument types";
static const char __pyx_k_Incompatible_checksums_s_vs_0x76[] = "Incompatible checksums (%s vs 0x762c537 = (peak_pairs, peak_set_a, peak_set_b, peak_type, score, shift))";
static const char __pyx_k_Incompatible_checksums_s_vs_0x79[] = "Incompatible checksums (%s vs 0x797b24e = (peak_a, peak_b, score))";
static const char __pyx_k_Incompatible_checksums_s_vs_0xd4[] = "Incompatible checksums (%s vs 0xd41d8cd = ())";
static const char __pyx_k_Non_native_byte_order_not_suppor[] = "Non-native byte order not supported";
static const char __pyx_k_ms_deisotope__c_similarity_metho[] = "ms_deisotope\\_c\\similarity_methods.pyx";
static const char __pyx_k_ndarray_is_not_Fortran_contiguou[] = "ndarray is not Fortran contiguous";
static const char __pyx_k_numpy_core_umath_failed_to_impor[] = "numpy.core.umath failed to import";
static const char __pyx_k_Format_string_allocated_too_shor_2[] = "Format string allocated too short.";
static const char __pyx_k_ms_deisotope__c_similarity_metho_2[] = "ms_deisotope._c.similarity_methods";
static PyObject *__pyx_kp_s_Cannot_handle_objects_of_type_s;
static PyObject *__pyx_n_s_Deconvoluted;
static PyObject *__pyx_n_s_DeconvolutedPeakSet;
static PyObject *__pyx_n_s_EnumBase;
static PyObject *__pyx_n_s_EnumType;
static PyObject *__pyx_kp_s_Expected_at_least_d_argument_s_g;
static PyObject *__pyx_n_s_Fitted;
static PyObject *__pyx_kp_u_Format_string_allocated_too_shor;
static PyObject *__pyx_kp_u_Format_string_allocated_too_shor_2;
static PyObject *__pyx_kp_s_Function_call_with_ambiguous_arg;
static PyObject *__pyx_n_s_ImportError;
static PyObject *__pyx_kp_s_Incompatible_checksums_s_vs_0x76;
static PyObject *__pyx_kp_s_Incompatible_checksums_s_vs_0x79;
static PyObject *__pyx_kp_s_Incompatible_checksums_s_vs_0xd4;
static PyObject *__pyx_n_s_IndexError;
static PyObject *__pyx_n_s_IntEnum;
static PyObject *__pyx_n_s_MemoryError;
static PyObject *__pyx_kp_s_No_matching_signature_found;
static PyObject *__pyx_kp_u_Non_native_byte_order_not_suppor;
static PyObject *__pyx_n_s_OrderedDict;
static PyObject *__pyx_n_s_PeakIndex;
static PyObject *__pyx_n_s_PeakMatch;
static PyObject *__pyx_n_s_PeakSet;
static PyObject *__pyx_n_s_PeakType;
static PyObject *__pyx_kp_s_Peak_set_types_must_match_got_s;
static PyObject *__pyx_n_s_PickleError;
static PyObject *__pyx_n_s_Pyx_EnumBase;
static PyObject *__pyx_n_s_Pyx_EnumBase___new;
static PyObject *__pyx_n_s_Pyx_EnumBase___repr;
static PyObject *__pyx_n_s_Pyx_EnumBase___str;
static PyObject *__pyx_n_s_RuntimeError;
static PyObject *__pyx_n_s_SimilarityMetrics;
static PyObject *__pyx_n_s_SpectrumAlignment;
static PyObject *__pyx_n_s_TypeError;
static PyObject *__pyx_kp_s_Unknown_enum_value_s;
static PyObject *__pyx_n_s_ValueError;
static PyObject *__pyx_kp_s__2;
static PyObject *__pyx_kp_s__3;
static PyObject *__pyx_kp_s__4;
static PyObject *__pyx_n_s_align;
static PyObject *__pyx_n_s_align_peaks;
static PyObject *__pyx_n_s_args;
static PyObject *__pyx_n_s_bin_peaks;
static PyObject *__pyx_n_s_calculate_score;
static PyObject *__pyx_n_s_class;
static PyObject *__pyx_n_s_cline_in_traceback;
static PyObject *__pyx_n_s_cls;
static PyObject *__pyx_n_s_collections;
static PyObject *__pyx_n_s_dct;
static PyObject *__pyx_n_s_defaults;
static PyObject *__pyx_n_s_determine_peak_type;
static PyObject *__pyx_n_s_dict;
static PyObject *__pyx_n_s_doc;
static PyObject *__pyx_n_s_dot_product;
static PyObject *__pyx_n_s_enum;
static PyObject *__pyx_n_s_error_tolerance;
static PyObject *__pyx_n_s_format;
static PyObject *__pyx_n_s_getstate;
static PyObject *__pyx_n_s_import;
static PyObject *__pyx_n_s_init;
static PyObject *__pyx_n_s_kwargs;
static PyObject *__pyx_n_s_main;
static PyObject *__pyx_n_s_members;
static PyObject *__pyx_n_s_metaclass;
static PyObject *__pyx_n_s_module;
static PyObject *__pyx_kp_s_ms_deisotope__c_peak_set;
static PyObject *__pyx_kp_s_ms_deisotope__c_similarity_metho;
static PyObject *__pyx_n_s_ms_deisotope__c_similarity_metho_2;
static PyObject *__pyx_kp_s_ms_peak_picker__c_peak_index;
static PyObject *__pyx_kp_s_ms_peak_picker__c_peak_set;
static PyObject *__pyx_n_s_name;
static PyObject *__pyx_n_s_name_2;
static PyObject *__pyx_kp_u_ndarray_is_not_C_contiguous;
static PyObject *__pyx_kp_u_ndarray_is_not_Fortran_contiguou;
static PyObject *__pyx_n_s_new;
static PyObject *__pyx_n_s_normalized_dot_product;
static PyObject *__pyx_n_s_np;
static PyObject *__pyx_n_s_numpy;
static PyObject *__pyx_kp_s_numpy_core_multiarray_failed_to;
static PyObject *__pyx_kp_s_numpy_core_umath_failed_to_impor;
static PyObject *__pyx_n_s_object;
static PyObject *__pyx_n_s_parents;
static PyObject *__pyx_n_s_peak_a;
static PyObject *__pyx_n_s_peak_b;
static PyObject *__pyx_n_s_peak_set_a;
static PyObject *__pyx_n_s_peak_set_b;
static PyObject *__pyx_n_s_peak_set_similarity;
static PyObject *__pyx_n_s_pickle;
static PyObject *__pyx_n_s_ppm_peak_set_similarity;
static PyObject *__pyx_n_s_precision;
static PyObject *__pyx_n_s_prepare;
static PyObject *__pyx_n_s_pyx_PickleError;
static PyObject *__pyx_n_s_pyx_checksum;
static PyObject *__pyx_n_s_pyx_fuse_0align_peaks;
static PyObject *__pyx_n_s_pyx_fuse_0bin_peaks;
static PyObject *__pyx_n_s_pyx_fuse_0peak_set_similarity;
static PyObject *__pyx_n_s_pyx_fuse_0ppm_peak_set_similar;
static PyObject *__pyx_n_s_pyx_fuse_1align_peaks;
static PyObject *__pyx_n_s_pyx_fuse_1bin_peaks;
static PyObject *__pyx_n_s_pyx_fuse_1peak_set_similarity;
static PyObject *__pyx_n_s_pyx_fuse_1ppm_peak_set_similar;
static PyObject *__pyx_n_s_pyx_fuse_2align_peaks;
static PyObject *__pyx_n_s_pyx_fuse_2bin_peaks;
static PyObject *__pyx_n_s_pyx_fuse_2peak_set_similarity;
static PyObject *__pyx_n_s_pyx_fuse_2ppm_peak_set_similar;
static PyObject *__pyx_n_s_pyx_fuse_3align_peaks;
static PyObject *__pyx_n_s_pyx_fuse_3bin_peaks;
static PyObject *__pyx_n_s_pyx_fuse_3peak_set_similarity;
static PyObject *__pyx_n_s_pyx_fuse_3ppm_peak_set_similar;
static PyObject *__pyx_n_s_pyx_result;
static PyObject *__pyx_n_s_pyx_state;
static PyObject *__pyx_n_s_pyx_type;
static PyObject *__pyx_n_s_pyx_unpickle_PeakMatch;
static PyObject *__pyx_n_s_pyx_unpickle_SpectrumAlignment;
static PyObject *__pyx_n_s_pyx_unpickle___Pyx_EnumMeta;
static PyObject *__pyx_n_s_pyx_vtable;
static PyObject *__pyx_n_s_qualname;
static PyObject *__pyx_n_s_range;
static PyObject *__pyx_n_s_reduce;
static PyObject *__pyx_n_s_reduce_cython;
static PyObject *__pyx_n_s_reduce_ex;
static PyObject *__pyx_n_s_repr;
static PyObject *__pyx_n_s_res;
static PyObject *__pyx_n_s_s;
static PyObject *__pyx_kp_s_s_s;
static PyObject *__pyx_kp_s_s_s_d;
static PyObject *__pyx_n_s_score;
static PyObject *__pyx_n_s_self;
static PyObject *__pyx_kp_s_self___class_____name___self_pe;
static PyObject *__pyx_n_s_setstate;
static PyObject *__pyx_n_s_setstate_cython;
static PyObject *__pyx_n_s_shift;
static PyObject *__pyx_n_s_signatures;
static PyObject *__pyx_n_s_split;
static PyObject *__pyx_n_s_str;
static PyObject *__pyx_kp_s_stringsource;
static PyObject *__pyx_n_s_strip;
static PyObject *__pyx_n_s_test;
static PyObject *__pyx_kp_u_unknown_dtype_code_in_numpy_pxd;
static PyObject *__pyx_n_s_update;
static PyObject *__pyx_n_s_v;
static PyObject *__pyx_n_s_value;
static PyObject *__pyx_n_s_values;
static PyObject *__pyx_n_s_zeros;
static int __pyx_pf_12ms_deisotope_2_c_18similarity_methods_9PeakMatch___init__(struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_PeakMatch *__pyx_v_self, PyObject *__pyx_v_peak_a, PyObject *__pyx_v_peak_b, PyObject *__pyx_v_score); /* proto */
static PyObject *__pyx_pf_12ms_deisotope_2_c_18similarity_methods_9PeakMatch_2_lt(struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_PeakMatch *__pyx_v_self, struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_PeakMatch *__pyx_v_other); /* proto */
static PyObject *__pyx_pf_12ms_deisotope_2_c_18similarity_methods_9PeakMatch_4_gt(struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_PeakMatch *__pyx_v_self, struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_PeakMatch *__pyx_v_other); /* proto */
static PyObject *__pyx_pf_12ms_deisotope_2_c_18similarity_methods_9PeakMatch_6_eq(struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_PeakMatch *__pyx_v_self, struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_PeakMatch *__pyx_v_other); /* proto */
static PyObject *__pyx_pf_12ms_deisotope_2_c_18similarity_methods_9PeakMatch_8__richcmp__(struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_PeakMatch *__pyx_v_self, struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_PeakMatch *__pyx_v_other, int __pyx_v_code); /* proto */
static PyObject *__pyx_pf_12ms_deisotope_2_c_18similarity_methods_9PeakMatch_10__getitem__(struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_PeakMatch *__pyx_v_self, PyObject *__pyx_v_i); /* proto */
static Py_ssize_t __pyx_pf_12ms_deisotope_2_c_18similarity_methods_9PeakMatch_12__len__(CYTHON_UNUSED struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_PeakMatch *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_12ms_deisotope_2_c_18similarity_methods_9PeakMatch_14__repr__(struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_PeakMatch *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_12ms_deisotope_2_c_18similarity_methods_9PeakMatch_6peak_a___get__(struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_PeakMatch *__pyx_v_self); /* proto */
static int __pyx_pf_12ms_deisotope_2_c_18similarity_methods_9PeakMatch_6peak_a_2__set__(struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_PeakMatch *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static int __pyx_pf_12ms_deisotope_2_c_18similarity_methods_9PeakMatch_6peak_a_4__del__(struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_PeakMatch *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_12ms_deisotope_2_c_18similarity_methods_9PeakMatch_6peak_b___get__(struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_PeakMatch *__pyx_v_self); /* proto */
static int __pyx_pf_12ms_deisotope_2_c_18similarity_methods_9PeakMatch_6peak_b_2__set__(struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_PeakMatch *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static int __pyx_pf_12ms_deisotope_2_c_18similarity_methods_9PeakMatch_6peak_b_4__del__(struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_PeakMatch *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_12ms_deisotope_2_c_18similarity_methods_9PeakMatch_5score___get__(struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_PeakMatch *__pyx_v_self); /* proto */
static int __pyx_pf_12ms_deisotope_2_c_18similarity_methods_9PeakMatch_5score_2__set__(struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_PeakMatch *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static PyObject *__pyx_pf_12ms_deisotope_2_c_18similarity_methods_9PeakMatch_16__reduce_cython__(struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_PeakMatch *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_12ms_deisotope_2_c_18similarity_methods_9PeakMatch_18__setstate_cython__(struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_PeakMatch *__pyx_v_self, PyObject *__pyx_v___pyx_state); /* proto */
static PyObject *__pyx_pf_12ms_deisotope_2_c_18similarity_methods_peak_set_similarity(CYTHON_UNUSED PyObject *__pyx_self, PyObject *__pyx_v_signatures, PyObject *__pyx_v_args, PyObject *__pyx_v_kwargs, CYTHON_UNUSED PyObject *__pyx_v_defaults); /* proto */
static PyObject *__pyx_pf_12ms_deisotope_2_c_18similarity_methods_10__pyx_fuse_0peak_set_similarity(CYTHON_UNUSED PyObject *__pyx_self, struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSet *__pyx_v_peak_set_a, struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSet *__pyx_v_peak_set_b, int __pyx_v_precision); /* proto */
static PyObject *__pyx_pf_12ms_deisotope_2_c_18similarity_methods_12__pyx_fuse_1peak_set_similarity(CYTHON_UNUSED PyObject *__pyx_self, struct __pyx_obj_14ms_peak_picker_2_c_10peak_index_PeakIndex *__pyx_v_peak_set_a, struct __pyx_obj_14ms_peak_picker_2_c_10peak_index_PeakIndex *__pyx_v_peak_set_b, int __pyx_v_precision); /* proto */
static PyObject *__pyx_pf_12ms_deisotope_2_c_18similarity_methods_14__pyx_fuse_2peak_set_similarity(CYTHON_UNUSED PyObject *__pyx_self, struct __pyx_obj_12ms_deisotope_2_c_8peak_set_DeconvolutedPeakSet *__pyx_v_peak_set_a, struct __pyx_obj_12ms_deisotope_2_c_8peak_set_DeconvolutedPeakSet *__pyx_v_peak_set_b, int __pyx_v_precision); /* proto */
static PyObject *__pyx_pf_12ms_deisotope_2_c_18similarity_methods_16__pyx_fuse_3peak_set_similarity(CYTHON_UNUSED PyObject *__pyx_self, PyObject *__pyx_v_peak_set_a, PyObject *__pyx_v_peak_set_b, int __pyx_v_precision); /* proto */
static PyObject *__pyx_pf_12ms_deisotope_2_c_18similarity_methods_2bin_peaks(CYTHON_UNUSED PyObject *__pyx_self, PyObject *__pyx_v_signatures, PyObject *__pyx_v_args, PyObject *__pyx_v_kwargs, CYTHON_UNUSED PyObject *__pyx_v_defaults); /* proto */
static PyObject *__pyx_pf_12ms_deisotope_2_c_18similarity_methods_20__pyx_fuse_0bin_peaks(CYTHON_UNUSED PyObject *__pyx_self, struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSet *__pyx_v_peak_set_a, struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSet *__pyx_v_peak_set_b, int __pyx_v_precision); /* proto */
static PyObject *__pyx_pf_12ms_deisotope_2_c_18similarity_methods_22__pyx_fuse_1bin_peaks(CYTHON_UNUSED PyObject *__pyx_self, struct __pyx_obj_14ms_peak_picker_2_c_10peak_index_PeakIndex *__pyx_v_peak_set_a, struct __pyx_obj_14ms_peak_picker_2_c_10peak_index_PeakIndex *__pyx_v_peak_set_b, int __pyx_v_precision); /* proto */
static PyObject *__pyx_pf_12ms_deisotope_2_c_18similarity_methods_24__pyx_fuse_2bin_peaks(CYTHON_UNUSED PyObject *__pyx_self, struct __pyx_obj_12ms_deisotope_2_c_8peak_set_DeconvolutedPeakSet *__pyx_v_peak_set_a, struct __pyx_obj_12ms_deisotope_2_c_8peak_set_DeconvolutedPeakSet *__pyx_v_peak_set_b, int __pyx_v_precision); /* proto */
static PyObject *__pyx_pf_12ms_deisotope_2_c_18similarity_methods_26__pyx_fuse_3bin_peaks(CYTHON_UNUSED PyObject *__pyx_self, PyObject *__pyx_v_peak_set_a, PyObject *__pyx_v_peak_set_b, int __pyx_v_precision); /* proto */
static int __pyx_pf_12ms_deisotope_2_c_18similarity_methods_17SpectrumAlignment___init__(struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_SpectrumAlignment *__pyx_v_self, PyObject *__pyx_v_peak_set_a, PyObject *__pyx_v_peak_set_b, double __pyx_v_error_tolerance, double __pyx_v_shift); /* proto */
static PyObject *__pyx_pf_12ms_deisotope_2_c_18similarity_methods_17SpectrumAlignment_2_determine_peak_type(struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_SpectrumAlignment *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_12ms_deisotope_2_c_18similarity_methods_17SpectrumAlignment_4align(struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_SpectrumAlignment *__pyx_v_self, double __pyx_v_error_tolerance, double __pyx_v_shift); /* proto */
static PyObject *__pyx_pf_12ms_deisotope_2_c_18similarity_methods_17SpectrumAlignment_6_calculate_score(struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_SpectrumAlignment *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_12ms_deisotope_2_c_18similarity_methods_17SpectrumAlignment_10peak_pairs___get__(struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_SpectrumAlignment *__pyx_v_self); /* proto */
static int __pyx_pf_12ms_deisotope_2_c_18similarity_methods_17SpectrumAlignment_10peak_pairs_2__set__(struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_SpectrumAlignment *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static int __pyx_pf_12ms_deisotope_2_c_18similarity_methods_17SpectrumAlignment_10peak_pairs_4__del__(struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_SpectrumAlignment *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_12ms_deisotope_2_c_18similarity_methods_17SpectrumAlignment_5shift___get__(struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_SpectrumAlignment *__pyx_v_self); /* proto */
static int __pyx_pf_12ms_deisotope_2_c_18similarity_methods_17SpectrumAlignment_5shift_2__set__(struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_SpectrumAlignment *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static PyObject *__pyx_pf_12ms_deisotope_2_c_18similarity_methods_17SpectrumAlignment_5score___get__(struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_SpectrumAlignment *__pyx_v_self); /* proto */
static int __pyx_pf_12ms_deisotope_2_c_18similarity_methods_17SpectrumAlignment_5score_2__set__(struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_SpectrumAlignment *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static PyObject *__pyx_pf_12ms_deisotope_2_c_18similarity_methods_17SpectrumAlignment_10peak_set_a___get__(struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_SpectrumAlignment *__pyx_v_self); /* proto */
static int __pyx_pf_12ms_deisotope_2_c_18similarity_methods_17SpectrumAlignment_10peak_set_a_2__set__(struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_SpectrumAlignment *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static int __pyx_pf_12ms_deisotope_2_c_18similarity_methods_17SpectrumAlignment_10peak_set_a_4__del__(struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_SpectrumAlignment *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_12ms_deisotope_2_c_18similarity_methods_17SpectrumAlignment_10peak_set_b___get__(struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_SpectrumAlignment *__pyx_v_self); /* proto */
static int __pyx_pf_12ms_deisotope_2_c_18similarity_methods_17SpectrumAlignment_10peak_set_b_2__set__(struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_SpectrumAlignment *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static int __pyx_pf_12ms_deisotope_2_c_18similarity_methods_17SpectrumAlignment_10peak_set_b_4__del__(struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_SpectrumAlignment *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_12ms_deisotope_2_c_18similarity_methods_17SpectrumAlignment_9peak_type___get__(struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_SpectrumAlignment *__pyx_v_self); /* proto */
static int __pyx_pf_12ms_deisotope_2_c_18similarity_methods_17SpectrumAlignment_9peak_type_2__set__(struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_SpectrumAlignment *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static PyObject *__pyx_pf_12ms_deisotope_2_c_18similarity_methods_17SpectrumAlignment_8__reduce_cython__(struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_SpectrumAlignment *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_12ms_deisotope_2_c_18similarity_methods_17SpectrumAlignment_10__setstate_cython__(struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_SpectrumAlignment *__pyx_v_self, PyObject *__pyx_v___pyx_state); /* proto */
static PyObject *__pyx_pf_12ms_deisotope_2_c_18similarity_methods_4ppm_peak_set_similarity(CYTHON_UNUSED PyObject *__pyx_self, PyObject *__pyx_v_signatures, PyObject *__pyx_v_args, PyObject *__pyx_v_kwargs, CYTHON_UNUSED PyObject *__pyx_v_defaults); /* proto */
static PyObject *__pyx_pf_12ms_deisotope_2_c_18similarity_methods_32__pyx_fuse_0ppm_peak_set_similarity(CYTHON_UNUSED PyObject *__pyx_self, struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSet *__pyx_v_peak_set_a, struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSet *__pyx_v_peak_set_b, double __pyx_v_error_tolerance); /* proto */
static PyObject *__pyx_pf_12ms_deisotope_2_c_18similarity_methods_34__pyx_fuse_1ppm_peak_set_similarity(CYTHON_UNUSED PyObject *__pyx_self, struct __pyx_obj_14ms_peak_picker_2_c_10peak_index_PeakIndex *__pyx_v_peak_set_a, struct __pyx_obj_14ms_peak_picker_2_c_10peak_index_PeakIndex *__pyx_v_peak_set_b, double __pyx_v_error_tolerance); /* proto */
static PyObject *__pyx_pf_12ms_deisotope_2_c_18similarity_methods_36__pyx_fuse_2ppm_peak_set_similarity(CYTHON_UNUSED PyObject *__pyx_self, struct __pyx_obj_12ms_deisotope_2_c_8peak_set_DeconvolutedPeakSet *__pyx_v_peak_set_a, struct __pyx_obj_12ms_deisotope_2_c_8peak_set_DeconvolutedPeakSet *__pyx_v_peak_set_b, double __pyx_v_error_tolerance); /* proto */
static PyObject *__pyx_pf_12ms_deisotope_2_c_18similarity_methods_38__pyx_fuse_3ppm_peak_set_similarity(CYTHON_UNUSED PyObject *__pyx_self, PyObject *__pyx_v_peak_set_a, PyObject *__pyx_v_peak_set_b, double __pyx_v_error_tolerance); /* proto */
static PyObject *__pyx_pf_12ms_deisotope_2_c_18similarity_methods_6align_peaks(CYTHON_UNUSED PyObject *__pyx_self, PyObject *__pyx_v_signatures, PyObject *__pyx_v_args, PyObject *__pyx_v_kwargs, CYTHON_UNUSED PyObject *__pyx_v_defaults); /* proto */
static PyObject *__pyx_pf_12ms_deisotope_2_c_18similarity_methods_42__pyx_fuse_0align_peaks(CYTHON_UNUSED PyObject *__pyx_self, struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSet *__pyx_v_peak_set_a, struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakSet *__pyx_v_peak_set_b, double __pyx_v_error_tolerance, double __pyx_v_shift); /* proto */
static PyObject *__pyx_pf_12ms_deisotope_2_c_18similarity_methods_44__pyx_fuse_1align_peaks(CYTHON_UNUSED PyObject *__pyx_self, struct __pyx_obj_14ms_peak_picker_2_c_10peak_index_PeakIndex *__pyx_v_peak_set_a, struct __pyx_obj_14ms_peak_picker_2_c_10peak_index_PeakIndex *__pyx_v_peak_set_b, double __pyx_v_error_tolerance, double __pyx_v_shift); /* proto */
static PyObject *__pyx_pf_12ms_deisotope_2_c_18similarity_methods_46__pyx_fuse_2align_peaks(CYTHON_UNUSED PyObject *__pyx_self, struct __pyx_obj_12ms_deisotope_2_c_8peak_set_DeconvolutedPeakSet *__pyx_v_peak_set_a, struct __pyx_obj_12ms_deisotope_2_c_8peak_set_DeconvolutedPeakSet *__pyx_v_peak_set_b, double __pyx_v_error_tolerance, double __pyx_v_shift); /* proto */
static PyObject *__pyx_pf_12ms_deisotope_2_c_18similarity_methods_48__pyx_fuse_3align_peaks(CYTHON_UNUSED PyObject *__pyx_self, PyObject *__pyx_v_peak_set_a, PyObject *__pyx_v_peak_set_b, double __pyx_v_error_tolerance, double __pyx_v_shift); /* proto */
static PyObject *__pyx_pf_12ms_deisotope_2_c_18similarity_methods_8__pyx_unpickle_PeakMatch(CYTHON_UNUSED PyObject *__pyx_self, PyObject *__pyx_v___pyx_type, long __pyx_v___pyx_checksum, PyObject *__pyx_v___pyx_state); /* proto */
static PyObject *__pyx_pf_12ms_deisotope_2_c_18similarity_methods_30__pyx_unpickle_SpectrumAlignment(CYTHON_UNUSED PyObject *__pyx_self, PyObject *__pyx_v___pyx_type, long __pyx_v___pyx_checksum, PyObject *__pyx_v___pyx_state); /* proto */
static int __pyx_pf_5numpy_7ndarray___getbuffer__(PyArrayObject *__pyx_v_self, Py_buffer *__pyx_v_info, int __pyx_v_flags); /* proto */
static void __pyx_pf_5numpy_7ndarray_2__releasebuffer__(PyArrayObject *__pyx_v_self, Py_buffer *__pyx_v_info); /* proto */
static int __pyx_pf_8EnumBase_14__Pyx_EnumMeta___init__(struct __pyx_obj___Pyx_EnumMeta *__pyx_v_cls, PyObject *__pyx_v_name, PyObject *__pyx_v_parents, PyObject *__pyx_v_dct); /* proto */
static PyObject *__pyx_pf_8EnumBase_14__Pyx_EnumMeta_2__iter__(struct __pyx_obj___Pyx_EnumMeta *__pyx_v_cls); /* proto */
static PyObject *__pyx_pf_8EnumBase_14__Pyx_EnumMeta_4__getitem__(struct __pyx_obj___Pyx_EnumMeta *__pyx_v_cls, PyObject *__pyx_v_name); /* proto */
static PyObject *__pyx_pf_8EnumBase_14__Pyx_EnumMeta_6__reduce_cython__(struct __pyx_obj___Pyx_EnumMeta *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_8EnumBase_14__Pyx_EnumMeta_8__setstate_cython__(struct __pyx_obj___Pyx_EnumMeta *__pyx_v_self, PyObject *__pyx_v___pyx_state); /* proto */
static PyObject *__pyx_pf_8EnumBase_14__Pyx_EnumBase___new__(CYTHON_UNUSED PyObject *__pyx_self, PyObject *__pyx_v_cls, PyObject *__pyx_v_value, PyObject *__pyx_v_name); /* proto */
static PyObject *__pyx_pf_8EnumBase_14__Pyx_EnumBase_2__repr__(CYTHON_UNUSED PyObject *__pyx_self, PyObject *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_8EnumBase_14__Pyx_EnumBase_4__str__(CYTHON_UNUSED PyObject *__pyx_self, PyObject *__pyx_v_self); /* proto */
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 *     bin_b = <double*>malloc(k * sizeof(double))
 *     if bin_a == NULL or bin_b == NULL:
 */
  __pyx_v_bin_a = ((double *)malloc((__pyx_v_k * (sizeof(double)))));

  /* "ms_deisotope/_c/similarity_methods.pyx":197
 *     k = <long>((hi * scaler) + 1)
 *     bin_a = <double*>malloc(k * sizeof(double))
 *     bin_b = <double*>malloc(k * sizeof(double))             # <<<<<<<<<<<<<<
 *     if bin_a == NULL or bin_b == NULL:
 *         if bin_a != NULL:
 */
  __pyx_v_bin_b = ((double *)malloc((__pyx_v_k * (sizeof(double)))));

  /* "ms_deisotope/_c/similarity_methods.pyx":198
 *     bin_a = <double*>malloc(k * sizeof(double))
 *     bin_b = <double*>malloc(k * sizeof(double))
 *     if bin_a == NULL or bin_b == NULL:             # <<<<<<<<<<<<<<
 *         if bin_a != NULL:
 *             free(bin_a)
 */
  __pyx_t_6 = ((__pyx_v_bin_a == NULL) != 0);
  if (!__pyx_t_6) {
  } else {
    __pyx_t_5 = __pyx_t_6;
    goto __pyx_L4_bool_binop_done;
  }
  __pyx_t_6 = ((__pyx_v_bin_b == NULL) != 0);
  __pyx_t_5 = __pyx_t_6;
  __pyx_L4_bool_binop_done:;
  if (__pyx_t_5) {

    /* "ms_deisotope/_c/similarity_methods.pyx":199
 *     bin_b = <double*>malloc(k * sizeof(double))
 *     if bin_a == NULL or bin_b == NULL:
 *         if bin_a != NULL:             # <<<<<<<<<<<<<<
 *             free(bin_a)
 *         if bin_b != NULL:
 */
    __pyx_t_5 = ((__pyx_v_bin_a != NULL) != 0);
    if (__pyx_t_5) {

      /* "ms_deisotope/_c/similarity_methods.pyx":200
 *     if bin_a == NULL or bin_b == NULL:
 *         if bin_a != NULL:
 *             free(bin_a)             # <<<<<<<<<<<<<<
 *         if bin_b != NULL:
 *             free(bin_b)
 */
      free(__pyx_v_bin_a);

      /* "ms_deisotope/_c/similarity_methods.pyx":199
 *     bin_b = <double*>malloc(k * sizeof(double))
 *     if bin_a == NULL or bin_b == NULL:
 *         if bin_a != NULL:             # <<<<<<<<<<<<<<
 *             free(bin_a)
 *         if bin_b != NULL:
 */
    }

    /* "ms_deisotope/_c/similarity_methods.pyx":201
 *         if bin_a != NULL:
 *             free(bin_a)
 *         if bin_b != NULL:             # <<<<<<<<<<<<<<
 *             free(bin_b)
 *         PyErr_SetString(MemoryError, "Could not allocate bins")
 */
    __pyx_t_5 = ((__pyx_v_bin_b != NULL) != 0);
    if (__pyx_t_5) {

      /* "ms_deisotope/_c/similarity_methods.pyx":202
 *             free(bin_a)
 *         if bin_b != NULL:
 *             free(bin_b)             # <<<<<<<<<<<<<<
 *         PyErr_SetString(MemoryError, "Could not allocate bins")
 *         return -1
 */
      free(__pyx_v_bin_b);

      /* "ms_deisotope/_c/similarity_methods.pyx":201
 *         if bin_a != NULL:
 *             free(bin_a)
 *         if bin_b != NULL:             # <<<<<<<<<<<<<<
 *             free(bin_b)
 *         PyErr_SetString(MemoryError, "Could not allocate bins")
 */
    }

    /* "ms_deisotope/_c/similarity_methods.pyx":203
 *         if bin_b != NULL:
 *             free(bin_b)
 *         PyErr_SetString(MemoryError, "Could not allocate bins")             # <<<<<<<<<<<<<<
 *         return -1
 *     for i in range(k):
 */
    PyErr_SetString(__pyx_builtin_MemoryError, ((char *)"Could not allocate bins"));

    /* "ms_deisotope/_c/similarity_methods.pyx":204
 *             free(bin_b)
 *         PyErr_SetString(MemoryError, "Could not allocate bins")
 *         return -1             # <<<<<<<<<<<<<<
 *     for i in range(k):
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 */
    __pyx_r = -1.0;
    goto __pyx_L0;

    /* "ms_deisotope/_c/similarity_methods.pyx":198
 *     bin_a = <double*>malloc(k * sizeof(double))
 *     bin_b = <double*>malloc(k * sizeof(double))
 *     if bin_a == NULL or bin_b == NULL:             # <<<<<<<<<<<<<<
 *         if bin_a != NULL:
 *             free(bin_a)
 */
  }

  /* "ms_deisotope/_c/similarity_methods.pyx":205
 *         PyErr_SetString(MemoryError, "Could not allocate bins")
 *         return -1
 *     for i in range(k):             # <<<<<<<<<<<<<<
 *         bin_a[i] = bin_b[i] = 0
 * 
 */
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  __pyx_t_8 = __pyx_t_7;
  for (__pyx_t_9 = 0; __pyx_t_9 < __pyx_t_8; __pyx_t_9+=1) {
    __pyx_v_i = __pyx_t_9;

    /* "ms_deisotope/_c/similarity_methods.pyx":206
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 *     for i in range(k):
 *         bin_a[i] = bin_b[i] = 0             # <<<<<<<<<<<<<<
 * 
 *     # Fill bins
 */
    (__pyx_v_bin_a[__pyx_v_i]) = 0.0;
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  /* "ms_deisotope/_c/similarity_methods.pyx":213
 *         n_peaks_a = len(_hold_a)
 *     else:
 *         n_peaks_a = peak_set_a.get_size()             # <<<<<<<<<<<<<<
 * 
 *     if peak_collection is object:
 */
  __pyx_v_n_peaks_a = ((struct __pyx_vtabstruct_14ms_peak_picker_2_c_8peak_set_PeakSet *)__pyx_v_peak_set_a->__pyx_vtab)->get_size(__pyx_v_peak_set_a);

  /* "ms_deisotope/_c/similarity_methods.pyx":219
 *         n_peaks_b = len(_hold_b)
 *     else:
 *         n_peaks_b = peak_set_b.get_size()             # <<<<<<<<<<<<<<
 * 
 *     if peak_collection is object:
 */
  __pyx_v_n_peaks_b = ((struct __pyx_vtabstruct_14ms_peak_picker_2_c_8peak_set_PeakSet *)__pyx_v_peak_set_b->__pyx_vtab)->get_size(__pyx_v_peak_set_b);

  /* "ms_deisotope/_c/similarity_methods.pyx":225
 *         items_b = _make_fast_array(_hold_b)
 *     else:
 *         items_a = _make_fast_array(peak_set_a)             # <<<<<<<<<<<<<<
 *         items_b = _make_fast_array(peak_set_b)
 *     with nogil:
 */
  __pyx_v_items_a = __pyx_fuse_0__pyx_f_12ms_deisotope_2_c_18similarity_methods__make_fast_array(__pyx_v_peak_set_a);

  /* "ms_deisotope/_c/similarity_methods.pyx":226
 *     else:
 *         items_a = _make_fast_array(peak_set_a)
 *         items_b = _make_fast_array(peak_set_b)             # <<<<<<<<<<<<<<
 *     with nogil:
 *         # Fill bins
 */
  __pyx_v_items_b = __pyx_fuse_0__pyx_f_12ms_deisotope_2_c_18similarity_methods__make_fast_array(__pyx_v_peak_set_b);

  /* "ms_deisotope/_c/similarity_methods.pyx":227
 *         items_a = _make_fast_array(peak_set_a)
 *         items_b = _make_fast_array(peak_set_b)
 *     with nogil:             # <<<<<<<<<<<<<<
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 *         for i in range(n_peaks_a):
 */
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      #ifdef WITH_THREAD
      PyThreadState *_save;
      Py_UNBLOCK_THREADS
      __Pyx_FastGIL_Remember();
      #endif
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        /* "ms_deisotope/_c/similarity_methods.pyx":229
 *     with nogil:
 *         # Fill bins
 *         for i in range(n_peaks_a):             # <<<<<<<<<<<<<<
 *             p_peak = items_a[i]
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 */
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          /* "ms_deisotope/_c/similarity_methods.pyx":230
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 */
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          /* "ms_deisotope/_c/similarity_methods.pyx":231
 *         for i in range(n_peaks_a):
 *             p_peak = items_a[i]
 *             index = int((<PeakBase>p_peak).mz * scaler)             # <<<<<<<<<<<<<<
 *             bin_a[index] += (<PeakBase>p_peak).intensity
 * 
 */
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 *             p_peak = items_a[i]
 *             index = int((<PeakBase>p_peak).mz * scaler)
 *             bin_a[index] += (<PeakBase>p_peak).intensity             # <<<<<<<<<<<<<<
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        /* "ms_deisotope/_c/similarity_methods.pyx":234
 *             bin_a[index] += (<PeakBase>p_peak).intensity
 * 
 *         for i in range(n_peaks_b):             # <<<<<<<<<<<<<<
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 */
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          /* "ms_deisotope/_c/similarity_methods.pyx":235
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 *         for i in range(n_peaks_b):
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 *             index = int((<PeakBase>p_peak).mz * scaler)
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 */
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          /* "ms_deisotope/_c/similarity_methods.pyx":236
 *         for i in range(n_peaks_b):
 *             p_peak = items_b[i]
 *             index = int((<PeakBase>p_peak).mz * scaler)             # <<<<<<<<<<<<<<
 *             bin_b[index] += (<PeakBase>p_peak).intensity
 * 
 */
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          /* "ms_deisotope/_c/similarity_methods.pyx":237
 *             p_peak = items_b[i]
 *             index = int((<PeakBase>p_peak).mz * scaler)
 *             bin_b[index] += (<PeakBase>p_peak).intensity             # <<<<<<<<<<<<<<
 * 
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 */
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        }

        /* "ms_deisotope/_c/similarity_methods.pyx":240
 * 
 *         # Calculate dot product and normalizers in parallel
 *         n = k             # <<<<<<<<<<<<<<
 *         for i in prange(n, schedule='static', num_threads=4):
 *             a = bin_a[i]
 */
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        /* "ms_deisotope/_c/similarity_methods.pyx":241
 *         # Calculate dot product and normalizers in parallel
 *         n = k
 *         for i in prange(n, schedule='static', num_threads=4):             # <<<<<<<<<<<<<<
 *             a = bin_a[i]
 *             b = bin_b[i]
 */
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            #if ((defined(__APPLE__) || defined(__OSX__)) && (defined(__GNUC__) && (__GNUC__ > 2 || (__GNUC__ == 2 && (__GNUC_MINOR__ > 95)))))
                #undef likely
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                    #pragma omp for lastprivate(__pyx_v_a) lastprivate(__pyx_v_b) firstprivate(__pyx_v_i) lastprivate(__pyx_v_i) schedule(static)
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                            __pyx_v_b = ((double)__PYX_NAN());

                            /* "ms_deisotope/_c/similarity_methods.pyx":242
 *         n = k
 *         for i in prange(n, schedule='static', num_threads=4):
 *             a = bin_a[i]             # <<<<<<<<<<<<<<
 *             b = bin_b[i]
 *             n_a += a * a
 */
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                            /* "ms_deisotope/_c/similarity_methods.pyx":243
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 *             a = bin_a[i]
 *             b = bin_b[i]             # <<<<<<<<<<<<<<
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 */
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                            /* "ms_deisotope/_c/similarity_methods.pyx":244
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 *             b = bin_b[i]
 *             n_a += a * a             # <<<<<<<<<<<<<<
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 */
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                            /* "ms_deisotope/_c/similarity_methods.pyx":245
 *             b = bin_b[i]
 *             n_a += a * a
 *             n_b += b * b             # <<<<<<<<<<<<<<
 *             z += a * b
 * 
 */
                            __pyx_v_n_b = (__pyx_v_n_b + (__pyx_v_b * __pyx_v_b));

                            /* "ms_deisotope/_c/similarity_methods.pyx":246
 *             n_a += a * a
 *             n_b += b * b
 *             z += a * b             # <<<<<<<<<<<<<<
 * 
 *         free(bin_a)
 */
                            __pyx_v_z = (__pyx_v_z + (__pyx_v_a * __pyx_v_b));
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        #if ((defined(__APPLE__) || defined(__OSX__)) && (defined(__GNUC__) && (__GNUC__ > 2 || (__GNUC__ == 2 && (__GNUC_MINOR__ > 95)))))
            #undef likely
            #undef unlikely
            #define likely(x)   __builtin_expect(!!(x), 1)
            #define unlikely(x) __builtin_expect(!!(x), 0)
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        /* "ms_deisotope/_c/similarity_methods.pyx":248
 *             z += a * b
 * 
 *         free(bin_a)             # <<<<<<<<<<<<<<
 *         free(bin_b)
 *         n_ab = sqrt(n_a) * sqrt(n_b)
 */
        free(__pyx_v_bin_a);

        /* "ms_deisotope/_c/similarity_methods.pyx":249
 * 
 *         free(bin_a)
 *         free(bin_b)             # <<<<<<<<<<<<<<
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 *         if n_ab == 0:
 */
        free(__pyx_v_bin_b);

        /* "ms_deisotope/_c/similarity_methods.pyx":250
 *         free(bin_a)
 *         free(bin_b)
 *         n_ab = sqrt(n_a) * sqrt(n_b)             # <<<<<<<<<<<<<<
 *         if n_ab == 0:
 *             return 0.0
 */
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        /* "ms_deisotope/_c/similarity_methods.pyx":251
 *         free(bin_b)
 *         n_ab = sqrt(n_a) * sqrt(n_b)
 *         if n_ab == 0:             # <<<<<<<<<<<<<<
 *             return 0.0
 *         return z / n_ab
 */
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 *         if n_ab == 0:
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 *         return z / n_ab
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 */
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 *         n_ab = sqrt(n_a) * sqrt(n_b)
 *         if n_ab == 0:             # <<<<<<<<<<<<<<
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 *         return z / n_ab
 */
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 * 
 */
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 *         items_b = _make_fast_array(peak_set_b)
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          goto __pyx_L0;
        }
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 *     """Computes the normalized dot product, also called cosine similarity between
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  /* function exit code */
  __pyx_L1_error:;
  __Pyx_XDECREF(__pyx_t_1);
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 *         peak = peak_set_a._mz_ordered[-1]
 *         hi = peak.mz             # <<<<<<<<<<<<<<
 *         peak = peak_set_b._mz_ordered[-1]
 *         hi = max(peak.mz, hi)
 */
  __pyx_t_2 = __pyx_v_peak->mz;
  __pyx_v_hi = __pyx_t_2;

  /* "ms_deisotope/_c/similarity_methods.pyx":190
 *         peak = peak_set_a._mz_ordered[-1]
 *         hi = peak.mz
 *         peak = peak_set_b._mz_ordered[-1]             # <<<<<<<<<<<<<<
 *         hi = max(peak.mz, hi)
 * 
 */
  if (unlikely(__pyx_v_peak_set_b->_mz_ordered == Py_None)) {
    PyErr_SetString(PyExc_TypeError, "'NoneType' object is not subscriptable");
    __PYX_ERR(0, 190, __pyx_L1_error)
  }
  __pyx_t_1 = __Pyx_GetItemInt_Tuple(__pyx_v_peak_set_b->_mz_ordered, -1L, long, 1, __Pyx_PyInt_From_long, 0, 1, 0); if (unlikely(!__pyx_t_1)) __PYX_ERR(0, 190, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_t_1);
  if (!(likely(((__pyx_t_1) == Py_None) || likely(__Pyx_TypeTest(__pyx_t_1, __pyx_ptype_14ms_peak_picker_2_c_8peak_set_PeakBase))))) __PYX_ERR(0, 190, __pyx_L1_error)
  __Pyx_DECREF_SET(__pyx_v_peak, ((struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakBase *)__pyx_t_1));
  __pyx_t_1 = 0;

  /* "ms_deisotope/_c/similarity_methods.pyx":191
 *         hi = peak.mz
 *         peak = peak_set_b._mz_ordered[-1]
 *         hi = max(peak.mz, hi)             # <<<<<<<<<<<<<<
 * 
 *     # Calculate bin array size and allocate memory
 */
  __pyx_t_2 = __pyx_v_hi;
  __pyx_t_3 = __pyx_v_peak->mz;
  if (((__pyx_t_2 > __pyx_t_3) != 0)) {
    __pyx_t_4 = __pyx_t_2;
  } else {
    __pyx_t_4 = __pyx_t_3;
  }
  __pyx_v_hi = __pyx_t_4;

  /* "ms_deisotope/_c/similarity_methods.pyx":194
 * 
 *     # Calculate bin array size and allocate memory
 *     scaler = 10 ** precision             # <<<<<<<<<<<<<<
 *     k = <long>((hi * scaler) + 1)
 *     bin_a = <double*>malloc(k * sizeof(double))
 */
  __pyx_v_scaler = __Pyx_pow_long(10, ((long)__pyx_v_precision));

  /* "ms_deisotope/_c/similarity_methods.pyx":195
 *     # Calculate bin array size and allocate memory
 *     scaler = 10 ** precision
 *     k = <long>((hi * scaler) + 1)             # <<<<<<<<<<<<<<
 *     bin_a = <double*>malloc(k * sizeof(double))
 *     bin_b = <double*>malloc(k * sizeof(double))
 */
  __pyx_v_k = ((long)((__pyx_v_hi * __pyx_v_scaler) + 1.0));

  /* "ms_deisotope/_c/similarity_methods.pyx":196
 *     scaler = 10 ** precision
 *     k = <long>((hi * scaler) + 1)
 *     bin_a = <double*>malloc(k * sizeof(double))             # <<<<<<<<<<<<<<
 *     bin_b = <double*>malloc(k * sizeof(double))
 *     if bin_a == NULL or bin_b == NULL:
 */
  __pyx_v_bin_a = ((double *)malloc((__pyx_v_k * (sizeof(double)))));

  /* "ms_deisotope/_c/similarity_methods.pyx":197
 *     k = <long>((hi * scaler) + 1)
 *     bin_a = <double*>malloc(k * sizeof(double))
 *     bin_b = <double*>malloc(k * sizeof(double))             # <<<<<<<<<<<<<<
 *     if bin_a == NULL or bin_b == NULL:
 *         if bin_a != NULL:
 */
  __pyx_v_bin_b = ((double *)malloc((__pyx_v_k * (sizeof(double)))));

  /* "ms_deisotope/_c/similarity_methods.pyx":198
 *     bin_a = <double*>malloc(k * sizeof(double))
 *     bin_b = <double*>malloc(k * sizeof(double))
 *     if bin_a == NULL or bin_b == NULL:             # <<<<<<<<<<<<<<
 *         if bin_a != NULL:
 *             free(bin_a)
 */
  __pyx_t_6 = ((__pyx_v_bin_a == NULL) != 0);
  if (!__pyx_t_6) {
  } else {
    __pyx_t_5 = __pyx_t_6;
    goto __pyx_L4_bool_binop_done;
  }
  __pyx_t_6 = ((__pyx_v_bin_b == NULL) != 0);
  __pyx_t_5 = __pyx_t_6;
  __pyx_L4_bool_binop_done:;
  if (__pyx_t_5) {

    /* "ms_deisotope/_c/similarity_methods.pyx":199
 *     bin_b = <double*>malloc(k * sizeof(double))
 *     if bin_a == NULL or bin_b == NULL:
 *         if bin_a != NULL:             # <<<<<<<<<<<<<<
 *             free(bin_a)
 *         if bin_b != NULL:
 */
    __pyx_t_5 = ((__pyx_v_bin_a != NULL) != 0);
    if (__pyx_t_5) {

      /* "ms_deisotope/_c/similarity_methods.pyx":200
 *     if bin_a == NULL or bin_b == NULL:
 *         if bin_a != NULL:
 *             free(bin_a)             # <<<<<<<<<<<<<<
 *         if bin_b != NULL:
 *             free(bin_b)
 */
      free(__pyx_v_bin_a);

      /* "ms_deisotope/_c/similarity_methods.pyx":199
 *     bin_b = <double*>malloc(k * sizeof(double))
 *     if bin_a == NULL or bin_b == NULL:
 *         if bin_a != NULL:             # <<<<<<<<<<<<<<
 *             free(bin_a)
 *         if bin_b != NULL:
 */
    }

    /* "ms_deisotope/_c/similarity_methods.pyx":201
 *         if bin_a != NULL:
 *             free(bin_a)
 *         if bin_b != NULL:             # <<<<<<<<<<<<<<
 *             free(bin_b)
 *         PyErr_SetString(MemoryError, "Could not allocate bins")
 */
    __pyx_t_5 = ((__pyx_v_bin_b != NULL) != 0);
    if (__pyx_t_5) {

      /* "ms_deisotope/_c/similarity_methods.pyx":202
 *             free(bin_a)
 *         if bin_b != NULL:
 *             free(bin_b)             # <<<<<<<<<<<<<<
 *         PyErr_SetString(MemoryError, "Could not allocate bins")
 *         return -1
 */
      free(__pyx_v_bin_b);

      /* "ms_deisotope/_c/similarity_methods.pyx":201
 *         if bin_a != NULL:
 *             free(bin_a)
 *         if bin_b != NULL:             # <<<<<<<<<<<<<<
 *             free(bin_b)
 *         PyErr_SetString(MemoryError, "Could not allocate bins")
 */
    }

    /* "ms_deisotope/_c/similarity_methods.pyx":203
 *         if bin_b != NULL:
 *             free(bin_b)
 *         PyErr_SetString(MemoryError, "Could not allocate bins")             # <<<<<<<<<<<<<<
 *         return -1
 *     for i in range(k):
 */
    PyErr_SetString(__pyx_builtin_MemoryError, ((char *)"Could not allocate bins"));

    /* "ms_deisotope/_c/similarity_methods.pyx":204
 *             free(bin_b)
 *         PyErr_SetString(MemoryError, "Could not allocate bins")
 *         return -1             # <<<<<<<<<<<<<<
 *     for i in range(k):
 *         bin_a[i] = bin_b[i] = 0
 */
    __pyx_r = -1.0;
    goto __pyx_L0;

    /* "ms_deisotope/_c/similarity_methods.pyx":198
 *     bin_a = <double*>malloc(k * sizeof(double))
 *     bin_b = <double*>malloc(k * sizeof(double))
 *     if bin_a == NULL or bin_b == NULL:             # <<<<<<<<<<<<<<
 *         if bin_a != NULL:
 *             free(bin_a)
 */
  }

  /* "ms_deisotope/_c/similarity_methods.pyx":205
 *         PyErr_SetString(MemoryError, "Could not allocate bins")
 *         return -1
 *     for i in range(k):             # <<<<<<<<<<<<<<
 *         bin_a[i] = bin_b[i] = 0
 * 
 */
  __pyx_t_7 = __pyx_v_k;
  __pyx_t_8 = __pyx_t_7;
  for (__pyx_t_9 = 0; __pyx_t_9 < __pyx_t_8; __pyx_t_9+=1) {
    __pyx_v_i = __pyx_t_9;

    /* "ms_deisotope/_c/similarity_methods.pyx":206
 *         return -1
 *     for i in range(k):
 *         bin_a[i] = bin_b[i] = 0             # <<<<<<<<<<<<<<
 * 
 *     # Fill bins
 */
    (__pyx_v_bin_a[__pyx_v_i]) = 0.0;
    (__pyx_v_bin_b[__pyx_v_i]) = 0.0;
  }

  /* "ms_deisotope/_c/similarity_methods.pyx":213
 *         n_peaks_a = len(_hold_a)
 *     else:
 *         n_peaks_a = peak_set_a.get_size()             # <<<<<<<<<<<<<<
 * 
 *     if peak_collection is object:
 */
  __pyx_v_n_peaks_a = ((struct __pyx_vtabstruct_12ms_deisotope_2_c_8peak_set_DeconvolutedPeakSet *)__pyx_v_peak_set_a->__pyx_vtab)->get_size(__pyx_v_peak_set_a);

  /* "ms_deisotope/_c/similarity_methods.pyx":219
 *         n_peaks_b = len(_hold_b)
 *     else:
 *         n_peaks_b = peak_set_b.get_size()             # <<<<<<<<<<<<<<
 * 
 *     if peak_collection is object:
 */
  __pyx_v_n_peaks_b = ((struct __pyx_vtabstruct_12ms_deisotope_2_c_8peak_set_DeconvolutedPeakSet *)__pyx_v_peak_set_b->__pyx_vtab)->get_size(__pyx_v_peak_set_b);

  /* "ms_deisotope/_c/similarity_methods.pyx":225
 *         items_b = _make_fast_array(_hold_b)
 *     else:
 *         items_a = _make_fast_array(peak_set_a)             # <<<<<<<<<<<<<<
 *         items_b = _make_fast_array(peak_set_b)
 *     with nogil:
 */
  __pyx_v_items_a = __pyx_fuse_2__pyx_f_12ms_deisotope_2_c_18similarity_methods__make_fast_array(__pyx_v_peak_set_a);

  /* "ms_deisotope/_c/similarity_methods.pyx":226
 *     else:
 *         items_a = _make_fast_array(peak_set_a)
 *         items_b = _make_fast_array(peak_set_b)             # <<<<<<<<<<<<<<
 *     with nogil:
 *         # Fill bins
 */
  __pyx_v_items_b = __pyx_fuse_2__pyx_f_12ms_deisotope_2_c_18similarity_methods__make_fast_array(__pyx_v_peak_set_b);

  /* "ms_deisotope/_c/similarity_methods.pyx":227
 *         items_a = _make_fast_array(peak_set_a)
 *         items_b = _make_fast_array(peak_set_b)
 *     with nogil:             # <<<<<<<<<<<<<<
 *         # Fill bins
 *         for i in range(n_peaks_a):
 */
  {
      #ifdef WITH_THREAD
      PyThreadState *_save;
      Py_UNBLOCK_THREADS
      __Pyx_FastGIL_Remember();
      #endif
      /*try:*/ {

        /* "ms_deisotope/_c/similarity_methods.pyx":229
 *     with nogil:
 *         # Fill bins
 *         for i in range(n_peaks_a):             # <<<<<<<<<<<<<<
 *             p_peak = items_a[i]
 *             index = int((<PeakBase>p_peak).mz * scaler)
 */
        __pyx_t_7 = __pyx_v_n_peaks_a;
        __pyx_t_8 = __pyx_t_7;
        for (__pyx_t_9 = 0; __pyx_t_9 < __pyx_t_8; __pyx_t_9+=1) {
          __pyx_v_i = __pyx_t_9;

          /* "ms_deisotope/_c/similarity_methods.pyx":230
 *         # Fill bins
 *         for i in range(n_peaks_a):
 *             p_peak = items_a[i]             # <<<<<<<<<<<<<<
 *             index = int((<PeakBase>p_peak).mz * scaler)
 *             bin_a[index] += (<PeakBase>p_peak).intensity
 */
          __pyx_v_p_peak = (__pyx_v_items_a[__pyx_v_i]);

          /* "ms_deisotope/_c/similarity_methods.pyx":231
 *         for i in range(n_peaks_a):
 *             p_peak = items_a[i]
 *             index = int((<PeakBase>p_peak).mz * scaler)             # <<<<<<<<<<<<<<
 *             bin_a[index] += (<PeakBase>p_peak).intensity
 * 
 */
          __pyx_v_index = ((long)(((struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakBase *)__pyx_v_p_peak)->mz * __pyx_v_scaler));

          /* "ms_deisotope/_c/similarity_methods.pyx":232
 *             p_peak = items_a[i]
 *             index = int((<PeakBase>p_peak).mz * scaler)
 *             bin_a[index] += (<PeakBase>p_peak).intensity             # <<<<<<<<<<<<<<
 * 
 *         for i in range(n_peaks_b):
 */
          __pyx_t_10 = __pyx_v_index;
          (__pyx_v_bin_a[__pyx_t_10]) = ((__pyx_v_bin_a[__pyx_t_10]) + ((struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakBase *)__pyx_v_p_peak)->intensity);
        }

        /* "ms_deisotope/_c/similarity_methods.pyx":234
 *             bin_a[index] += (<PeakBase>p_peak).intensity
 * 
 *         for i in range(n_peaks_b):             # <<<<<<<<<<<<<<
 *             p_peak = items_b[i]
 *             index = int((<PeakBase>p_peak).mz * scaler)
 */
        __pyx_t_7 = __pyx_v_n_peaks_b;
        __pyx_t_8 = __pyx_t_7;
        for (__pyx_t_9 = 0; __pyx_t_9 < __pyx_t_8; __pyx_t_9+=1) {
          __pyx_v_i = __pyx_t_9;

          /* "ms_deisotope/_c/similarity_methods.pyx":235
 * 
 *         for i in range(n_peaks_b):
 *             p_peak = items_b[i]             # <<<<<<<<<<<<<<
 *             index = int((<PeakBase>p_peak).mz * scaler)
 *             bin_b[index] += (<PeakBase>p_peak).intensity
 */
          __pyx_v_p_peak = (__pyx_v_items_b[__pyx_v_i]);

          /* "ms_deisotope/_c/similarity_methods.pyx":236
 *         for i in range(n_peaks_b):
 *             p_peak = items_b[i]
 *             index = int((<PeakBase>p_peak).mz * scaler)             # <<<<<<<<<<<<<<
 *             bin_b[index] += (<PeakBase>p_peak).intensity
 * 
 */
          __pyx_v_index = ((long)(((struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakBase *)__pyx_v_p_peak)->mz * __pyx_v_scaler));

          /* "ms_deisotope/_c/similarity_methods.pyx":237
 *             p_peak = items_b[i]
 *             index = int((<PeakBase>p_peak).mz * scaler)
 *             bin_b[index] += (<PeakBase>p_peak).intensity             # <<<<<<<<<<<<<<
 * 
 *         # Calculate dot product and normalizers in parallel
 */
          __pyx_t_10 = __pyx_v_index;
          (__pyx_v_bin_b[__pyx_t_10]) = ((__pyx_v_bin_b[__pyx_t_10]) + ((struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakBase *)__pyx_v_p_peak)->intensity);
        }

        /* "ms_deisotope/_c/similarity_methods.pyx":240
 * 
 *         # Calculate dot product and normalizers in parallel
 *         n = k             # <<<<<<<<<<<<<<
 *         for i in prange(n, schedule='static', num_threads=4):
 *             a = bin_a[i]
 */
        __pyx_v_n = __pyx_v_k;

        /* "ms_deisotope/_c/similarity_methods.pyx":241
 *         # Calculate dot product and normalizers in parallel
 *         n = k
 *         for i in prange(n, schedule='static', num_threads=4):             # <<<<<<<<<<<<<<
 *             a = bin_a[i]
 *             b = bin_b[i]
 */
        __pyx_t_7 = __pyx_v_n;
        if (1 == 0) abort();
        {
            #if ((defined(__APPLE__) || defined(__OSX__)) && (defined(__GNUC__) && (__GNUC__ > 2 || (__GNUC__ == 2 && (__GNUC_MINOR__ > 95)))))
                #undef likely
                #undef unlikely
                #define likely(x)   (x)
                #define unlikely(x) (x)
            #endif
            __pyx_t_9 = (__pyx_t_7 - 0 + 1 - 1/abs(1)) / 1;
            if (__pyx_t_9 > 0)
            {
                #ifdef _OPENMP
                #pragma omp parallel reduction(+:__pyx_v_n_a) reduction(+:__pyx_v_n_b) reduction(+:__pyx_v_z) num_threads(4)
                #endif /* _OPENMP */
                {
                    #ifdef _OPENMP
                    #pragma omp for lastprivate(__pyx_v_a) lastprivate(__pyx_v_b) firstprivate(__pyx_v_i) lastprivate(__pyx_v_i) schedule(static)
                    #endif /* _OPENMP */
                    for (__pyx_t_8 = 0; __pyx_t_8 < __pyx_t_9; __pyx_t_8++){
                        {
                            __pyx_v_i = (long)(0 + 1 * __pyx_t_8);
                            /* Initialize private variables to invalid values */
                            __pyx_v_a = ((double)__PYX_NAN());
                            __pyx_v_b = ((double)__PYX_NAN());

                            /* "ms_deisotope/_c/similarity_methods.pyx":242
 *         n = k
 *         for i in prange(n, schedule='static', num_threads=4):
 *             a = bin_a[i]             # <<<<<<<<<<<<<<
 *             b = bin_b[i]
 *             n_a += a * a
 */
                            __pyx_v_a = (__pyx_v_bin_a[__pyx_v_i]);

                            /* "ms_deisotope/_c/similarity_methods.pyx":243
 *         for i in prange(n, schedule='static', num_threads=4):
 *             a = bin_a[i]
 *             b = bin_b[i]             # <<<<<<<<<<<<<<
 *             n_a += a * a
 *             n_b += b * b
 */
                            __pyx_v_b = (__pyx_v_bin_b[__pyx_v_i]);

                            /* "ms_deisotope/_c/similarity_methods.pyx":244
 *             a = bin_a[i]
 *             b = bin_b[i]
 *             n_a += a * a             # <<<<<<<<<<<<<<
 *             n_b += b * b
 *             z += a * b
 */
                            __pyx_v_n_a = (__pyx_v_n_a + (__pyx_v_a * __pyx_v_a));

                            /* "ms_deisotope/_c/similarity_methods.pyx":245
 *             b = bin_b[i]
 *             n_a += a * a
 *             n_b += b * b             # <<<<<<<<<<<<<<
 *             z += a * b
 * 
 */
                            __pyx_v_n_b = (__pyx_v_n_b + (__pyx_v_b * __pyx_v_b));

                            /* "ms_deisotope/_c/similarity_methods.pyx":246
 *             n_a += a * a
 *             n_b += b * b
 *             z += a * b             # <<<<<<<<<<<<<<
 * 
 *         free(bin_a)
 */
                            __pyx_v_z = (__pyx_v_z + (__pyx_v_a * __pyx_v_b));
                        }
                    }
                }
            }
        }
        #if ((defined(__APPLE__) || defined(__OSX__)) && (defined(__GNUC__) && (__GNUC__ > 2 || (__GNUC__ == 2 && (__GNUC_MINOR__ > 95)))))
            #undef likely
            #undef unlikely
            #define likely(x)   __builtin_expect(!!(x), 1)
            #define unlikely(x) __builtin_expect(!!(x), 0)
        #endif

        /* "ms_deisotope/_c/similarity_methods.pyx":248
 *             z += a * b
 * 
 *         free(bin_a)             # <<<<<<<<<<<<<<
 *         free(bin_b)
 *         n_ab = sqrt(n_a) * sqrt(n_b)
 */
        free(__pyx_v_bin_a);

        /* "ms_deisotope/_c/similarity_methods.pyx":249
 * 
 *         free(bin_a)
 *         free(bin_b)             # <<<<<<<<<<<<<<
 *         n_ab = sqrt(n_a) * sqrt(n_b)
 *         if n_ab == 0:
 */
        free(__pyx_v_bin_b);

        /* "ms_deisotope/_c/similarity_methods.pyx":250
 *         free(bin_a)
 *         free(bin_b)
 *         n_ab = sqrt(n_a) * sqrt(n_b)             # <<<<<<<<<<<<<<
 *         if n_ab == 0:
 *             return 0.0
 */
        __pyx_v_n_ab = (sqrt(__pyx_v_n_a) * sqrt(__pyx_v_n_b));

        /* "ms_deisotope/_c/similarity_methods.pyx":251
 *         free(bin_b)
 *         n_ab = sqrt(n_a) * sqrt(n_b)
 *         if n_ab == 0:             # <<<<<<<<<<<<<<
 *             return 0.0
 *         return z / n_ab
 */
        __pyx_t_5 = ((__pyx_v_n_ab == 0.0) != 0);
        if (__pyx_t_5) {

          /* "ms_deisotope/_c/similarity_methods.pyx":252
 *         n_ab = sqrt(n_a) * sqrt(n_b)
 *         if n_ab == 0:
 *             return 0.0             # <<<<<<<<<<<<<<
 *         return z / n_ab
 * 
 */
          __pyx_r = 0.0;
          goto __pyx_L10_return;

          /* "ms_deisotope/_c/similarity_methods.pyx":251
 *         free(bin_b)
 *         n_ab = sqrt(n_a) * sqrt(n_b)
 *         if n_ab == 0:             # <<<<<<<<<<<<<<
 *             return 0.0
 *         return z / n_ab
 */
        }

        /* "ms_deisotope/_c/similarity_methods.pyx":253
 *         if n_ab == 0:
 *             return 0.0
 *         return z / n_ab             # <<<<<<<<<<<<<<
 * 
 * 
 */
        __pyx_r = (__pyx_v_z / __pyx_v_n_ab);
        goto __pyx_L10_return;
      }

      /* "ms_deisotope/_c/similarity_methods.pyx":227
 *         items_a = _make_fast_array(peak_set_a)
 *         items_b = _make_fast_array(peak_set_b)
 *     with nogil:             # <<<<<<<<<<<<<<
 *         # Fill bins
 *         for i in range(n_peaks_a):
 */
      /*finally:*/ {
        __pyx_L10_return: {
          #ifdef WITH_THREAD
          __Pyx_FastGIL_Forget();
          Py_BLOCK_THREADS
          #endif
          goto __pyx_L0;
        }
      }
  }

  /* "ms_deisotope/_c/similarity_methods.pyx":126
 * @cython.boundscheck(False)
 * @cython.cdivision(True)
 * cpdef double peak_set_similarity(peak_collection peak_set_a, peak_collection peak_set_b, int precision=0) except -1:             # <<<<<<<<<<<<<<
 *     """Computes the normalized dot product, also called cosine similarity between
 *     two peak sets, a similarity metric ranging between 0 (dissimilar) to 1.0 (similar).
 */

  /* function exit code */
  __pyx_L1_error:;
  __Pyx_XDECREF(__pyx_t_1);
  __Pyx_AddTraceback("ms_deisotope._c.similarity_methods.peak_set_similarity", __pyx_clineno, __pyx_lineno, __pyx_filename);
  __pyx_r = -1.0;
  __pyx_L0:;
  __Pyx_XDECREF((PyObject *)__pyx_v_peak);
  __Pyx_RefNannyFinishContext();
  return __pyx_r;
}

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  /* "ms_deisotope/_c/similarity_methods.pyx":195
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 */
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  /* "ms_deisotope/_c/similarity_methods.pyx":196
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 *     bin_b = <double*>malloc(k * sizeof(double))
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 */
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  /* "ms_deisotope/_c/similarity_methods.pyx":197
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 *     bin_a = <double*>malloc(k * sizeof(double))
 *     bin_b = <double*>malloc(k * sizeof(double))             # <<<<<<<<<<<<<<
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 */
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 */
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      /* "ms_deisotope/_c/similarity_methods.pyx":200
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 */
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      /* "ms_deisotope/_c/similarity_methods.pyx":199
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 */
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 *             free(bin_a)
 *         if bin_b != NULL:             # <<<<<<<<<<<<<<
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 */
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      /* "ms_deisotope/_c/similarity_methods.pyx":202
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 *         if bin_b != NULL:
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 */
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      /* "ms_deisotope/_c/similarity_methods.pyx":201
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 *             free(bin_a)
 *         if bin_b != NULL:             # <<<<<<<<<<<<<<
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 *         PyErr_SetString(MemoryError, "Could not allocate bins")
 */
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    /* "ms_deisotope/_c/similarity_methods.pyx":203
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 *             free(bin_b)
 *         PyErr_SetString(MemoryError, "Could not allocate bins")             # <<<<<<<<<<<<<<
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 */
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    /* "ms_deisotope/_c/similarity_methods.pyx":204
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 *         PyErr_SetString(MemoryError, "Could not allocate bins")
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 *     if peak_collection is object:
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 */
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 */
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static struct __pyx_vtabstruct_12ms_deisotope_2_c_18similarity_methods_PeakMatch __pyx_vtable_12ms_deisotope_2_c_18similarity_methods_PeakMatch;

static struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_PeakMatch *__pyx_freelist_12ms_deisotope_2_c_18similarity_methods_PeakMatch[10000];
static int __pyx_freecount_12ms_deisotope_2_c_18similarity_methods_PeakMatch = 0;

static PyObject *__pyx_tp_new_12ms_deisotope_2_c_18similarity_methods_PeakMatch(PyTypeObject *t, CYTHON_UNUSED PyObject *a, CYTHON_UNUSED PyObject *k) {
  struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_PeakMatch *p;
  PyObject *o;
  if (CYTHON_COMPILING_IN_CPYTHON && likely((__pyx_freecount_12ms_deisotope_2_c_18similarity_methods_PeakMatch > 0) & (t->tp_basicsize == sizeof(struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_PeakMatch)))) {
    o = (PyObject*)__pyx_freelist_12ms_deisotope_2_c_18similarity_methods_PeakMatch[--__pyx_freecount_12ms_deisotope_2_c_18similarity_methods_PeakMatch];
    memset(o, 0, sizeof(struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_PeakMatch));
    (void) PyObject_INIT(o, t);
    PyObject_GC_Track(o);
  } else {
    o = (*t->tp_alloc)(t, 0);
    if (unlikely(!o)) return 0;
  }
  p = ((struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_PeakMatch *)o);
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  p->peak_a = ((struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakBase *)Py_None); Py_INCREF(Py_None);
  p->peak_b = ((struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakBase *)Py_None); Py_INCREF(Py_None);
  return o;
}

static void __pyx_tp_dealloc_12ms_deisotope_2_c_18similarity_methods_PeakMatch(PyObject *o) {
  struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_PeakMatch *p = (struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_PeakMatch *)o;
  PyObject_GC_UnTrack(o);
  Py_CLEAR(p->peak_a);
  Py_CLEAR(p->peak_b);
  if (CYTHON_COMPILING_IN_CPYTHON && ((__pyx_freecount_12ms_deisotope_2_c_18similarity_methods_PeakMatch < 10000) & (Py_TYPE(o)->tp_basicsize == sizeof(struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_PeakMatch)))) {
    __pyx_freelist_12ms_deisotope_2_c_18similarity_methods_PeakMatch[__pyx_freecount_12ms_deisotope_2_c_18similarity_methods_PeakMatch++] = ((struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_PeakMatch *)o);
  } else {
    (*Py_TYPE(o)->tp_free)(o);
  }
}

static int __pyx_tp_traverse_12ms_deisotope_2_c_18similarity_methods_PeakMatch(PyObject *o, visitproc v, void *a) {
  int e;
  struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_PeakMatch *p = (struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_PeakMatch *)o;
  if (p->peak_a) {
    e = (*v)(((PyObject *)p->peak_a), a); if (e) return e;
  }
  if (p->peak_b) {
    e = (*v)(((PyObject *)p->peak_b), a); if (e) return e;
  }
  return 0;
}

static int __pyx_tp_clear_12ms_deisotope_2_c_18similarity_methods_PeakMatch(PyObject *o) {
  PyObject* tmp;
  struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_PeakMatch *p = (struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_PeakMatch *)o;
  tmp = ((PyObject*)p->peak_a);
  p->peak_a = ((struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakBase *)Py_None); Py_INCREF(Py_None);
  Py_XDECREF(tmp);
  tmp = ((PyObject*)p->peak_b);
  p->peak_b = ((struct __pyx_obj_14ms_peak_picker_2_c_8peak_set_PeakBase *)Py_None); Py_INCREF(Py_None);
  Py_XDECREF(tmp);
  return 0;
}
static PyObject *__pyx_sq_item_12ms_deisotope_2_c_18similarity_methods_PeakMatch(PyObject *o, Py_ssize_t i) {
  PyObject *r;
  PyObject *x = PyInt_FromSsize_t(i); if(!x) return 0;
  r = Py_TYPE(o)->tp_as_mapping->mp_subscript(o, x);
  Py_DECREF(x);
  return r;
}

static PyObject *__pyx_getprop_12ms_deisotope_2_c_18similarity_methods_9PeakMatch_peak_a(PyObject *o, CYTHON_UNUSED void *x) {
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}

static int __pyx_setprop_12ms_deisotope_2_c_18similarity_methods_9PeakMatch_peak_a(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
  if (v) {
    return __pyx_pw_12ms_deisotope_2_c_18similarity_methods_9PeakMatch_6peak_a_3__set__(o, v);
  }
  else {
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  }
}

static PyObject *__pyx_getprop_12ms_deisotope_2_c_18similarity_methods_9PeakMatch_peak_b(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_12ms_deisotope_2_c_18similarity_methods_9PeakMatch_6peak_b_1__get__(o);
}

static int __pyx_setprop_12ms_deisotope_2_c_18similarity_methods_9PeakMatch_peak_b(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
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    return __pyx_pw_12ms_deisotope_2_c_18similarity_methods_9PeakMatch_6peak_b_3__set__(o, v);
  }
  else {
    return __pyx_pw_12ms_deisotope_2_c_18similarity_methods_9PeakMatch_6peak_b_5__del__(o);
  }
}

static PyObject *__pyx_getprop_12ms_deisotope_2_c_18similarity_methods_9PeakMatch_score(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_12ms_deisotope_2_c_18similarity_methods_9PeakMatch_5score_1__get__(o);
}

static int __pyx_setprop_12ms_deisotope_2_c_18similarity_methods_9PeakMatch_score(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
  if (v) {
    return __pyx_pw_12ms_deisotope_2_c_18similarity_methods_9PeakMatch_5score_3__set__(o, v);
  }
  else {
    PyErr_SetString(PyExc_NotImplementedError, "__del__");
    return -1;
  }
}

static PyMethodDef __pyx_methods_12ms_deisotope_2_c_18similarity_methods_PeakMatch[] = {
  {"_lt", (PyCFunction)__pyx_pw_12ms_deisotope_2_c_18similarity_methods_9PeakMatch_3_lt, METH_O, __pyx_doc_12ms_deisotope_2_c_18similarity_methods_9PeakMatch_2_lt},
  {"_gt", (PyCFunction)__pyx_pw_12ms_deisotope_2_c_18similarity_methods_9PeakMatch_5_gt, METH_O, __pyx_doc_12ms_deisotope_2_c_18similarity_methods_9PeakMatch_4_gt},
  {"_eq", (PyCFunction)__pyx_pw_12ms_deisotope_2_c_18similarity_methods_9PeakMatch_7_eq, METH_O, __pyx_doc_12ms_deisotope_2_c_18similarity_methods_9PeakMatch_6_eq},
  {"__reduce_cython__", (PyCFunction)__pyx_pw_12ms_deisotope_2_c_18similarity_methods_9PeakMatch_17__reduce_cython__, METH_NOARGS, __pyx_doc_12ms_deisotope_2_c_18similarity_methods_9PeakMatch_16__reduce_cython__},
  {"__setstate_cython__", (PyCFunction)__pyx_pw_12ms_deisotope_2_c_18similarity_methods_9PeakMatch_19__setstate_cython__, METH_O, __pyx_doc_12ms_deisotope_2_c_18similarity_methods_9PeakMatch_18__setstate_cython__},
  {0, 0, 0, 0}
};

static struct PyGetSetDef __pyx_getsets_12ms_deisotope_2_c_18similarity_methods_PeakMatch[] = {
  {(char *)"peak_a", __pyx_getprop_12ms_deisotope_2_c_18similarity_methods_9PeakMatch_peak_a, __pyx_setprop_12ms_deisotope_2_c_18similarity_methods_9PeakMatch_peak_a, (char *)"peak_a: ms_peak_picker._c.peak_set.PeakBase", 0},
  {(char *)"peak_b", __pyx_getprop_12ms_deisotope_2_c_18similarity_methods_9PeakMatch_peak_b, __pyx_setprop_12ms_deisotope_2_c_18similarity_methods_9PeakMatch_peak_b, (char *)"peak_b: ms_peak_picker._c.peak_set.PeakBase", 0},
  {(char *)"score", __pyx_getprop_12ms_deisotope_2_c_18similarity_methods_9PeakMatch_score, __pyx_setprop_12ms_deisotope_2_c_18similarity_methods_9PeakMatch_score, (char *)"score: 'double'", 0},
  {0, 0, 0, 0, 0}
};

static PySequenceMethods __pyx_tp_as_sequence_PeakMatch = {
  __pyx_pw_12ms_deisotope_2_c_18similarity_methods_9PeakMatch_13__len__, /*sq_length*/
  0, /*sq_concat*/
  0, /*sq_repeat*/
  __pyx_sq_item_12ms_deisotope_2_c_18similarity_methods_PeakMatch, /*sq_item*/
  0, /*sq_slice*/
  0, /*sq_ass_item*/
  0, /*sq_ass_slice*/
  0, /*sq_contains*/
  0, /*sq_inplace_concat*/
  0, /*sq_inplace_repeat*/
};

static PyMappingMethods __pyx_tp_as_mapping_PeakMatch = {
  __pyx_pw_12ms_deisotope_2_c_18similarity_methods_9PeakMatch_13__len__, /*mp_length*/
  __pyx_pw_12ms_deisotope_2_c_18similarity_methods_9PeakMatch_11__getitem__, /*mp_subscript*/
  0, /*mp_ass_subscript*/
};

static PyTypeObject __pyx_type_12ms_deisotope_2_c_18similarity_methods_PeakMatch = {
  PyVarObject_HEAD_INIT(0, 0)
  "ms_deisotope._c.similarity_methods.PeakMatch", /*tp_name*/
  sizeof(struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_PeakMatch), /*tp_basicsize*/
  0, /*tp_itemsize*/
  __pyx_tp_dealloc_12ms_deisotope_2_c_18similarity_methods_PeakMatch, /*tp_dealloc*/
  #if PY_VERSION_HEX < 0x030800b4
  0, /*tp_print*/
  #endif
  #if PY_VERSION_HEX >= 0x030800b4
  0, /*tp_vectorcall_offset*/
  #endif
  0, /*tp_getattr*/
  0, /*tp_setattr*/
  #if PY_MAJOR_VERSION < 3
  0, /*tp_compare*/
  #endif
  #if PY_MAJOR_VERSION >= 3
  0, /*tp_as_async*/
  #endif
  __pyx_pw_12ms_deisotope_2_c_18similarity_methods_9PeakMatch_15__repr__, /*tp_repr*/
  0, /*tp_as_number*/
  &__pyx_tp_as_sequence_PeakMatch, /*tp_as_sequence*/
  &__pyx_tp_as_mapping_PeakMatch, /*tp_as_mapping*/
  0, /*tp_hash*/
  0, /*tp_call*/
  0, /*tp_str*/
  0, /*tp_getattro*/
  0, /*tp_setattro*/
  0, /*tp_as_buffer*/
  Py_TPFLAGS_DEFAULT|Py_TPFLAGS_HAVE_VERSION_TAG|Py_TPFLAGS_CHECKTYPES|Py_TPFLAGS_HAVE_NEWBUFFER|Py_TPFLAGS_HAVE_GC, /*tp_flags*/
  "PeakMatch(peak_a, peak_b, score=0.0)", /*tp_doc*/
  __pyx_tp_traverse_12ms_deisotope_2_c_18similarity_methods_PeakMatch, /*tp_traverse*/
  __pyx_tp_clear_12ms_deisotope_2_c_18similarity_methods_PeakMatch, /*tp_clear*/
  __pyx_pw_12ms_deisotope_2_c_18similarity_methods_9PeakMatch_9__richcmp__, /*tp_richcompare*/
  0, /*tp_weaklistoffset*/
  0, /*tp_iter*/
  0, /*tp_iternext*/
  __pyx_methods_12ms_deisotope_2_c_18similarity_methods_PeakMatch, /*tp_methods*/
  0, /*tp_members*/
  __pyx_getsets_12ms_deisotope_2_c_18similarity_methods_PeakMatch, /*tp_getset*/
  0, /*tp_base*/
  0, /*tp_dict*/
  0, /*tp_descr_get*/
  0, /*tp_descr_set*/
  0, /*tp_dictoffset*/
  __pyx_pw_12ms_deisotope_2_c_18similarity_methods_9PeakMatch_1__init__, /*tp_init*/
  0, /*tp_alloc*/
  __pyx_tp_new_12ms_deisotope_2_c_18similarity_methods_PeakMatch, /*tp_new*/
  0, /*tp_free*/
  0, /*tp_is_gc*/
  0, /*tp_bases*/
  0, /*tp_mro*/
  0, /*tp_cache*/
  0, /*tp_subclasses*/
  0, /*tp_weaklist*/
  0, /*tp_del*/
  0, /*tp_version_tag*/
  #if PY_VERSION_HEX >= 0x030400a1
  0, /*tp_finalize*/
  #endif
  #if PY_VERSION_HEX >= 0x030800b1
  0, /*tp_vectorcall*/
  #endif
  #if PY_VERSION_HEX >= 0x030800b4 && PY_VERSION_HEX < 0x03090000
  0, /*tp_print*/
  #endif
};
static struct __pyx_vtabstruct_12ms_deisotope_2_c_18similarity_methods_SpectrumAlignment __pyx_vtable_12ms_deisotope_2_c_18similarity_methods_SpectrumAlignment;

static PyObject *__pyx_tp_new_12ms_deisotope_2_c_18similarity_methods_SpectrumAlignment(PyTypeObject *t, CYTHON_UNUSED PyObject *a, CYTHON_UNUSED PyObject *k) {
  struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_SpectrumAlignment *p;
  PyObject *o;
  if (likely((t->tp_flags & Py_TPFLAGS_IS_ABSTRACT) == 0)) {
    o = (*t->tp_alloc)(t, 0);
  } else {
    o = (PyObject *) PyBaseObject_Type.tp_new(t, __pyx_empty_tuple, 0);
  }
  if (unlikely(!o)) return 0;
  p = ((struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_SpectrumAlignment *)o);
  p->__pyx_vtab = __pyx_vtabptr_12ms_deisotope_2_c_18similarity_methods_SpectrumAlignment;
  p->peak_pairs = ((PyObject*)Py_None); Py_INCREF(Py_None);
  p->peak_set_a = Py_None; Py_INCREF(Py_None);
  p->peak_set_b = Py_None; Py_INCREF(Py_None);
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}

static void __pyx_tp_dealloc_12ms_deisotope_2_c_18similarity_methods_SpectrumAlignment(PyObject *o) {
  struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_SpectrumAlignment *p = (struct __pyx_obj_12ms_deisotope_2_c_18similarity_methods_SpectrumAlignment *)o;
  #if CYTHON_USE_TP_FINALIZE
  if (unlikely(PyType_HasFeature(Py_TYPE(o), Py_TPFLAGS_HAVE_FINALIZE) && Py_TYPE(o)->tp_finalize) && !_PyGC_FINALIZED(o)) {
    if (PyObject_CallFinalizerFromDealloc(o)) return;
  }
  #endif
  PyObject_GC_UnTrack(o);
  Py_CLEAR(p->peak_pairs);
  Py_CLEAR(p->peak_set_a);
  Py_CLEAR(p->peak_set_b);
  (*Py_TYPE(o)->tp_free)(o);
}

static int __pyx_tp_traverse_12ms_deisotope_2_c_18similarity_methods_SpectrumAlignment(PyObject *o, visitproc v, void *a) {
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    e = (*v)(p->peak_set_a, a); if (e) return e;
  }
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  }
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}

static int __pyx_tp_clear_12ms_deisotope_2_c_18similarity_methods_SpectrumAlignment(PyObject *o) {
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}

/* PyIntCompare */
static CYTHON_INLINE PyObject* __Pyx_PyInt_EqObjC(PyObject *op1, PyObject *op2, CYTHON_UNUSED long intval, CYTHON_UNUSED long inplace) {
    if (op1 == op2) {
        Py_RETURN_TRUE;
    }
    #if PY_MAJOR_VERSION < 3
    if (likely(PyInt_CheckExact(op1))) {
        const long b = intval;
        long a = PyInt_AS_LONG(op1);
        if (a == b) Py_RETURN_TRUE; else Py_RETURN_FALSE;
    }
    #endif
    #if CYTHON_USE_PYLONG_INTERNALS
    if (likely(PyLong_CheckExact(op1))) {
        int unequal;
        unsigned long uintval;
        Py_ssize_t size = Py_SIZE(op1);
        const digit* digits = ((PyLongObject*)op1)->ob_digit;
        if (intval == 0) {
            if (size == 0) Py_RETURN_TRUE; else Py_RETURN_FALSE;
        } else if (intval < 0) {
            if (size >= 0)
                Py_RETURN_FALSE;
            intval = -intval;
            size = -size;
        } else {
            if (size <= 0)
                Py_RETURN_FALSE;
        }
        uintval = (unsigned long) intval;
#if PyLong_SHIFT * 4 < SIZEOF_LONG*8
        if (uintval >> (PyLong_SHIFT * 4)) {
            unequal = (size != 5) || (digits[0] != (uintval & (unsigned long) PyLong_MASK))
                 | (digits[1] != ((uintval >> (1 * PyLong_SHIFT)) & (unsigned long) PyLong_MASK)) | (digits[2] != ((uintval >> (2 * PyLong_SHIFT)) & (unsigned long) PyLong_MASK)) | (digits[3] != ((uintval >> (3 * PyLong_SHIFT)) & (unsigned long) PyLong_MASK)) | (digits[4] != ((uintval >> (4 * PyLong_SHIFT)) & (unsigned long) PyLong_MASK));
        } else
#endif
#if PyLong_SHIFT * 3 < SIZEOF_LONG*8
        if (uintval >> (PyLong_SHIFT * 3)) {
            unequal = (size != 4) || (digits[0] != (uintval & (unsigned long) PyLong_MASK))
                 | (digits[1] != ((uintval >> (1 * PyLong_SHIFT)) & (unsigned long) PyLong_MASK)) | (digits[2] != ((uintval >> (2 * PyLong_SHIFT)) & (unsigned long) PyLong_MASK)) | (digits[3] != ((uintval >> (3 * PyLong_SHIFT)) & (unsigned long) PyLong_MASK));
        } else
#endif
#if PyLong_SHIFT * 2 < SIZEOF_LONG*8
        if (uintval >> (PyLong_SHIFT * 2)) {
            unequal = (size != 3) || (digits[0] != (uintval & (unsigned long) PyLong_MASK))
                 | (digits[1] != ((uintval >> (1 * PyLong_SHIFT)) & (unsigned long) PyLong_MASK)) | (digits[2] != ((uintval >> (2 * PyLong_SHIFT)) & (unsigned long) PyLong_MASK));
        } else
#endif
#if PyLong_SHIFT * 1 < SIZEOF_LONG*8
        if (uintval >> (PyLong_SHIFT * 1)) {
            unequal = (size != 2) || (digits[0] != (uintval & (unsigned long) PyLong_MASK))
                 | (digits[1] != ((uintval >> (1 * PyLong_SHIFT)) & (unsigned long) PyLong_MASK));
        } else
#endif
            unequal = (size != 1) || (((unsigned long) digits[0]) != (uintval & (unsigned long) PyLong_MASK));
        if (unequal == 0) Py_RETURN_TRUE; else Py_RETURN_FALSE;
    }
    #endif
    if (PyFloat_CheckExact(op1)) {
        const long b = intval;
        double a = PyFloat_AS_DOUBLE(op1);
        if ((double)a == (double)b) Py_RETURN_TRUE; else Py_RETURN_FALSE;
    }
    return (
        PyObject_RichCompare(op1, op2, Py_EQ));
}

/* PyCFunctionFastCall */
#if CYTHON_FAST_PYCCALL
static CYTHON_INLINE PyObject * __Pyx_PyCFunction_FastCall(PyObject *func_obj, PyObject **args, Py_ssize_t nargs) {
    PyCFunctionObject *func = (PyCFunctionObject*)func_obj;
    PyCFunction meth = PyCFunction_GET_FUNCTION(func);
    PyObject *self = PyCFunction_GET_SELF(func);
    int flags = PyCFunction_GET_FLAGS(func);
    assert(PyCFunction_Check(func));
    assert(METH_FASTCALL == (flags & ~(METH_CLASS | METH_STATIC | METH_COEXIST | METH_KEYWORDS | METH_STACKLESS)));
    assert(nargs >= 0);
    assert(nargs == 0 || args != NULL);
    /* _PyCFunction_FastCallDict() must not be called with an exception set,
       because it may clear it (directly or indirectly) and so the
       caller loses its exception */
    assert(!PyErr_Occurred());
    if ((PY_VERSION_HEX < 0x030700A0) || unlikely(flags & METH_KEYWORDS)) {
        return (*((__Pyx_PyCFunctionFastWithKeywords)(void*)meth)) (self, args, nargs, NULL);
    } else {
        return (*((__Pyx_PyCFunctionFast)(void*)meth)) (self, args, nargs);
    }
}
#endif

/* PyFunctionFastCall */
#if CYTHON_FAST_PYCALL
static PyObject* __Pyx_PyFunction_FastCallNoKw(PyCodeObject *co, PyObject **args, Py_ssize_t na,
                                               PyObject *globals) {
    PyFrameObject *f;
    PyThreadState *tstate = __Pyx_PyThreadState_Current;
    PyObject **fastlocals;
    Py_ssize_t i;
    PyObject *result;
    assert(globals != NULL);
    /* XXX Perhaps we should create a specialized
       PyFrame_New() that doesn't take locals, but does
       take builtins without sanity checking them.
       */
    assert(tstate != NULL);
    f = PyFrame_New(tstate, co, globals, NULL);
    if (f == NULL) {
        return NULL;
    }
    fastlocals = __Pyx_PyFrame_GetLocalsplus(f);
    for (i = 0; i < na; i++) {
        Py_INCREF(*args);
        fastlocals[i] = *args++;
    }
    result = PyEval_EvalFrameEx(f,0);
    ++tstate->recursion_depth;
    Py_DECREF(f);
    --tstate->recursion_depth;
    return result;
}
#if 1 || PY_VERSION_HEX < 0x030600B1
static PyObject *__Pyx_PyFunction_FastCallDict(PyObject *func, PyObject **args, Py_ssize_t nargs, PyObject *kwargs) {
    PyCodeObject *co = (PyCodeObject *)PyFunction_GET_CODE(func);
    PyObject *globals = PyFunction_GET_GLOBALS(func);
    PyObject *argdefs = PyFunction_GET_DEFAULTS(func);
    PyObject *closure;
#if PY_MAJOR_VERSION >= 3
    PyObject *kwdefs;
#endif
    PyObject *kwtuple, **k;
    PyObject **d;
    Py_ssize_t nd;
    Py_ssize_t nk;
    PyObject *result;
    assert(kwargs == NULL || PyDict_Check(kwargs));
    nk = kwargs ? PyDict_Size(kwargs) : 0;
    if (Py_EnterRecursiveCall((char*)" while calling a Python object")) {
        return NULL;
    }
    if (
#if PY_MAJOR_VERSION >= 3
            co->co_kwonlyargcount == 0 &&
#endif
            likely(kwargs == NULL || nk == 0) &&
            co->co_flags == (CO_OPTIMIZED | CO_NEWLOCALS | CO_NOFREE)) {
        if (argdefs == NULL && co->co_argcount == nargs) {
            result = __Pyx_PyFunction_FastCallNoKw(co, args, nargs, globals);
            goto done;
        }
        else if (nargs == 0 && argdefs != NULL
                 && co->co_argcount == Py_SIZE(argdefs)) {
            /* function called with no arguments, but all parameters have
               a default value: use default values as arguments .*/
            args = &PyTuple_GET_ITEM(argdefs, 0);
            result =__Pyx_PyFunction_FastCallNoKw(co, args, Py_SIZE(argdefs), globals);
            goto done;
        }
    }
    if (kwargs != NULL) {
        Py_ssize_t pos, i;
        kwtuple = PyTuple_New(2 * nk);
        if (kwtuple == NULL) {
            result = NULL;
            goto done;
        }
        k = &PyTuple_GET_ITEM(kwtuple, 0);
        pos = i = 0;
        while (PyDict_Next(kwargs, &pos, &k[i], &k[i+1])) {
            Py_INCREF(k[i]);
            Py_INCREF(k[i+1]);
            i += 2;
        }
        nk = i / 2;
    }
    else {
        kwtuple = NULL;
        k = NULL;
    }
    closure = PyFunction_GET_CLOSURE(func);
#if PY_MAJOR_VERSION >= 3
    kwdefs = PyFunction_GET_KW_DEFAULTS(func);
#endif
    if (argdefs != NULL) {
        d = &PyTuple_GET_ITEM(argdefs, 0);
        nd = Py_SIZE(argdefs);
    }
    else {
        d = NULL;
        nd = 0;
    }
#if PY_MAJOR_VERSION >= 3
    result = PyEval_EvalCodeEx((PyObject*)co, globals, (PyObject *)NULL,
                               args, (int)nargs,
                               k, (int)nk,
                               d, (int)nd, kwdefs, closure);
#else
    result = PyEval_EvalCodeEx(co, globals, (PyObject *)NULL,
                               args, (int)nargs,
                               k, (int)nk,
                               d, (int)nd, closure);
#endif
    Py_XDECREF(kwtuple);
done:
    Py_LeaveRecursiveCall();
    return result;
}
#endif
#endif

/* PyObjectCall */
#if CYTHON_COMPILING_IN_CPYTHON
static CYTHON_INLINE PyObject* __Pyx_PyObject_Call(PyObject *func, PyObject *arg, PyObject *kw) {
    PyObject *result;
    ternaryfunc call = func->ob_type->tp_call;
    if (unlikely(!call))
        return PyObject_Call(func, arg, kw);
    if (unlikely(Py_EnterRecursiveCall((char*)" while calling a Python object")))
        return NULL;
    result = (*call)(func, arg, kw);
    Py_LeaveRecursiveCall();
    if (unlikely(!result) && unlikely(!PyErr_Occurred())) {
        PyErr_SetString(
            PyExc_SystemError,
            "NULL result without error in PyObject_Call");
    }
    return result;
}
#endif

/* PyObjectCallMethO */
#if CYTHON_COMPILING_IN_CPYTHON
static CYTHON_INLINE PyObject* __Pyx_PyObject_CallMethO(PyObject *func, PyObject *arg) {
    PyObject *self, *result;
    PyCFunction cfunc;
    cfunc = PyCFunction_GET_FUNCTION(func);
    self = PyCFunction_GET_SELF(func);
    if (unlikely(Py_EnterRecursiveCall((char*)" while calling a Python object")))
        return NULL;
    result = cfunc(self, arg);
    Py_LeaveRecursiveCall();
    if (unlikely(!result) && unlikely(!PyErr_Occurred())) {
        PyErr_SetString(
            PyExc_SystemError,
            "NULL result without error in PyObject_Call");
    }
    return result;
}
#endif

/* PyObjectCallOneArg */
#if CYTHON_COMPILING_IN_CPYTHON
static PyObject* __Pyx__PyObject_CallOneArg(PyObject *func, PyObject *arg) {
    PyObject *result;
    PyObject *args = PyTuple_New(1);
    if (unlikely(!args)) return NULL;
    Py_INCREF(arg);
    PyTuple_SET_ITEM(args, 0, arg);
    result = __Pyx_PyObject_Call(func, args, NULL);
    Py_DECREF(args);
    return result;
}
static CYTHON_INLINE PyObject* __Pyx_PyObject_CallOneArg(PyObject *func, PyObject *arg) {
#if CYTHON_FAST_PYCALL
    if (PyFunction_Check(func)) {
        return __Pyx_PyFunction_FastCall(func, &arg, 1);
    }
#endif
    if (likely(PyCFunction_Check(func))) {
        if (likely(PyCFunction_GET_FLAGS(func) & METH_O)) {
            return __Pyx_PyObject_CallMethO(func, arg);
#if CYTHON_FAST_PYCCALL
        } else if (PyCFunction_GET_FLAGS(func) & METH_FASTCALL) {
            return __Pyx_PyCFunction_FastCall(func, &arg, 1);
#endif
        }
    }
    return __Pyx__PyObject_CallOneArg(func, arg);
}
#else
static CYTHON_INLINE PyObject* __Pyx_PyObject_CallOneArg(PyObject *func, PyObject *arg) {
    PyObject *result;
    PyObject *args = PyTuple_Pack(1, arg);
    if (unlikely(!args)) return NULL;
    result = __Pyx_PyObject_Call(func, args, NULL);
    Py_DECREF(args);
    return result;
}
#endif

/* RaiseException */
#if PY_MAJOR_VERSION < 3
static void __Pyx_Raise(PyObject *type, PyObject *value, PyObject *tb,
                        CYTHON_UNUSED PyObject *cause) {
    __Pyx_PyThreadState_declare
    Py_XINCREF(type);
    if (!value || value == Py_None)
        value = NULL;
    else
        Py_INCREF(value);
    if (!tb || tb == Py_None)
        tb = NULL;
    else {
        Py_INCREF(tb);
        if (!PyTraceBack_Check(tb)) {
            PyErr_SetString(PyExc_TypeError,
                "raise: arg 3 must be a traceback or None");
            goto raise_error;
        }
    }
    if (PyType_Check(type)) {
#if CYTHON_COMPILING_IN_PYPY
        if (!value) {
            Py_INCREF(Py_None);
            value = Py_None;
        }
#endif
        PyErr_NormalizeException(&type, &value, &tb);
    } else {
        if (value) {
            PyErr_SetString(PyExc_TypeError,
                "instance exception may not have a separate value");
            goto raise_error;
        }
        value = type;
        type = (PyObject*) Py_TYPE(type);
        Py_INCREF(type);
        if (!PyType_IsSubtype((PyTypeObject *)type, (PyTypeObject *)PyExc_BaseException)) {
            PyErr_SetString(PyExc_TypeError,
                "raise: exception class must be a subclass of BaseException");
            goto raise_error;
        }
    }
    __Pyx_PyThreadState_assign
    __Pyx_ErrRestore(type, value, tb);
    return;
raise_error:
    Py_XDECREF(value);
    Py_XDECREF(type);
    Py_XDECREF(tb);
    return;
}
#else
static void __Pyx_Raise(PyObject *type, PyObject *value, PyObject *tb, PyObject *cause) {
    PyObject* owned_instance = NULL;
    if (tb == Py_None) {
        tb = 0;
    } else if (tb && !PyTraceBack_Check(tb)) {
        PyErr_SetString(PyExc_TypeError,
            "raise: arg 3 must be a traceback or None");
        goto bad;
    }
    if (value == Py_None)
        value = 0;
    if (PyExceptionInstance_Check(type)) {
        if (value) {
            PyErr_SetString(PyExc_TypeError,
                "instance exception may not have a separate value");
            goto bad;
        }
        value = type;
        type = (PyObject*) Py_TYPE(value);
    } else if (PyExceptionClass_Check(type)) {
        PyObject *instance_class = NULL;
        if (value && PyExceptionInstance_Check(value)) {
            instance_class = (PyObject*) Py_TYPE(value);
            if (instance_class != type) {
                int is_subclass = PyObject_IsSubclass(instance_class, type);
                if (!is_subclass) {
                    instance_class = NULL;
                } else if (unlikely(is_subclass == -1)) {
                    goto bad;
                } else {
                    type = instance_class;
                }
            }
        }
        if (!instance_class) {
            PyObject *args;
            if (!value)
                args = PyTuple_New(0);
            else if (PyTuple_Check(value)) {
                Py_INCREF(value);
                args = value;
            } else
                args = PyTuple_Pack(1, value);
            if (!args)
                goto bad;
            owned_instance = PyObject_Call(type, args, NULL);
            Py_DECREF(args);
            if (!owned_instance)
                goto bad;
            value = owned_instance;
            if (!PyExceptionInstance_Check(value)) {
                PyErr_Format(PyExc_TypeError,
                             "calling %R should have returned an instance of "
                             "BaseException, not %R",
                             type, Py_TYPE(value));
                goto bad;
            }
        }
    } else {
        PyErr_SetString(PyExc_TypeError,
            "raise: exception class must be a subclass of BaseException");
        goto bad;
    }
    if (cause) {
        PyObject *fixed_cause;
        if (cause == Py_None) {
            fixed_cause = NULL;
        } else if (PyExceptionClass_Check(cause)) {
            fixed_cause = PyObject_CallObject(cause, NULL);
            if (fixed_cause == NULL)
                goto bad;
        } else if (PyExceptionInstance_Check(cause)) {
            fixed_cause = cause;
            Py_INCREF(fixed_cause);
        } else {
            PyErr_SetString(PyExc_TypeError,
                            "exception causes must derive from "
                            "BaseException");
            goto bad;
        }
        PyException_SetCause(value, fixed_cause);
    }
    PyErr_SetObject(type, value);
    if (tb) {
#if CYTHON_COMPILING_IN_PYPY
        PyObject *tmp_type, *tmp_value, *tmp_tb;
        PyErr_Fetch(&tmp_type, &tmp_value, &tmp_tb);
        Py_INCREF(tb);
        PyErr_Restore(tmp_type, tmp_value, tb);
        Py_XDECREF(tmp_tb);
#else
        PyThreadState *tstate = __Pyx_PyThreadState_Current;
        PyObject* tmp_tb = tstate->curexc_traceback;
        if (tb != tmp_tb) {
            Py_INCREF(tb);
            tstate->curexc_traceback = tb;
            Py_XDECREF(tmp_tb);
        }
#endif
    }
bad:
    Py_XDECREF(owned_instance);
    return;
}
#endif

/* PyErrExceptionMatches */
#if CYTHON_FAST_THREAD_STATE
static int __Pyx_PyErr_ExceptionMatchesTuple(PyObject *exc_type, PyObject *tuple) {
    Py_ssize_t i, n;
    n = PyTuple_GET_SIZE(tuple);
#if PY_MAJOR_VERSION >= 3
    for (i=0; i<n; i++) {
        if (exc_type == PyTuple_GET_ITEM(tuple, i)) return 1;
    }
#endif
    for (i=0; i<n; i++) {
        if (__Pyx_PyErr_GivenExceptionMatches(exc_type, PyTuple_GET_ITEM(tuple, i))) return 1;
    }
    return 0;
}
static CYTHON_INLINE int __Pyx_PyErr_ExceptionMatchesInState(PyThreadState* tstate, PyObject* err) {
    PyObject *exc_type = tstate->curexc_type;
    if (exc_type == err) return 1;
    if (unlikely(!exc_type)) return 0;
    if (unlikely(PyTuple_Check(err)))
        return __Pyx_PyErr_ExceptionMatchesTuple(exc_type, err);
    return __Pyx_PyErr_GivenExceptionMatches(exc_type, err);
}
#endif

/* GetAttr */
static CYTHON_INLINE PyObject *__Pyx_GetAttr(PyObject *o, PyObject *n) {
#if CYTHON_USE_TYPE_SLOTS
#if PY_MAJOR_VERSION >= 3
    if (likely(PyUnicode_Check(n)))
#else
    if (likely(PyString_Check(n)))
#endif
        return __Pyx_PyObject_GetAttrStr(o, n);
#endif
    return PyObject_GetAttr(o, n);
}

/* GetAttr3 */
static PyObject *__Pyx_GetAttr3Default(PyObject *d) {
    __Pyx_PyThreadState_declare
    __Pyx_PyThreadState_assign
    if (unlikely(!__Pyx_PyErr_ExceptionMatches(PyExc_AttributeError)))
        return NULL;
    __Pyx_PyErr_Clear();
    Py_INCREF(d);
    return d;
}
static CYTHON_INLINE PyObject *__Pyx_GetAttr3(PyObject *o, PyObject *n, PyObject *d) {
    PyObject *r = __Pyx_GetAttr(o, n);
    return (likely(r)) ? r : __Pyx_GetAttr3Default(d);
}

/* PyDictVersioning */
#if CYTHON_USE_DICT_VERSIONS && CYTHON_USE_TYPE_SLOTS
static CYTHON_INLINE PY_UINT64_T __Pyx_get_tp_dict_version(PyObject *obj) {
    PyObject *dict = Py_TYPE(obj)->tp_dict;
    return likely(dict) ? __PYX_GET_DICT_VERSION(dict) : 0;
}
static CYTHON_INLINE PY_UINT64_T __Pyx_get_object_dict_version(PyObject *obj) {
    PyObject **dictptr = NULL;
    Py_ssize_t offset = Py_TYPE(obj)->tp_dictoffset;
    if (offset) {
#if CYTHON_COMPILING_IN_CPYTHON
        dictptr = (likely(offset > 0)) ? (PyObject **) ((char *)obj + offset) : _PyObject_GetDictPtr(obj);
#else
        dictptr = _PyObject_GetDictPtr(obj);
#endif
    }
    return (dictptr && *dictptr) ? __PYX_GET_DICT_VERSION(*dictptr) : 0;
}
static CYTHON_INLINE int __Pyx_object_dict_version_matches(PyObject* obj, PY_UINT64_T tp_dict_version, PY_UINT64_T obj_dict_version) {
    PyObject *dict = Py_TYPE(obj)->tp_dict;
    if (unlikely(!dict) || unlikely(tp_dict_version != __PYX_GET_DICT_VERSION(dict)))
        return 0;
    return obj_dict_version == __Pyx_get_object_dict_version(obj);
}
#endif

/* GetModuleGlobalName */
#if CYTHON_USE_DICT_VERSIONS
static PyObject *__Pyx__GetModuleGlobalName(PyObject *name, PY_UINT64_T *dict_version, PyObject **dict_cached_value)
#else
static CYTHON_INLINE PyObject *__Pyx__GetModuleGlobalName(PyObject *name)
#endif
{
    PyObject *result;
#if !CYTHON_AVOID_BORROWED_REFS
#if CYTHON_COMPILING_IN_CPYTHON && PY_VERSION_HEX >= 0x030500A1
    result = _PyDict_GetItem_KnownHash(__pyx_d, name, ((PyASCIIObject *) name)->hash);
    __PYX_UPDATE_DICT_CACHE(__pyx_d, result, *dict_cached_value, *dict_version)
    if (likely(result)) {
        return __Pyx_NewRef(result);
    } else if (unlikely(PyErr_Occurred())) {
        return NULL;
    }
#else
    result = PyDict_GetItem(__pyx_d, name);
    __PYX_UPDATE_DICT_CACHE(__pyx_d, result, *dict_cached_value, *dict_version)
    if (likely(result)) {
        return __Pyx_NewRef(result);
    }
#endif
#else
    result = PyObject_GetItem(__pyx_d, name);
    __PYX_UPDATE_DICT_CACHE(__pyx_d, result, *dict_cached_value, *dict_version)
    if (likely(result)) {
        return __Pyx_NewRef(result);
    }
    PyErr_Clear();
#endif
    return __Pyx_GetBuiltinName(name);
}

/* DictGetItem */
#if PY_MAJOR_VERSION >= 3 && !CYTHON_COMPILING_IN_PYPY
static PyObject *__Pyx_PyDict_GetItem(PyObject *d, PyObject* key) {
    PyObject *value;
    value = PyDict_GetItemWithError(d, key);
    if (unlikely(!value)) {
        if (!PyErr_Occurred()) {
            if (unlikely(PyTuple_Check(key))) {
                PyObject* args = PyTuple_Pack(1, key);
                if (likely(args)) {
                    PyErr_SetObject(PyExc_KeyError, args);
                    Py_DECREF(args);
                }
            } else {
                PyErr_SetObject(PyExc_KeyError, key);
            }
        }
        return NULL;
    }
    Py_INCREF(value);
    return value;
}
#endif

/* SetItemInt */
static int __Pyx_SetItemInt_Generic(PyObject *o, PyObject *j, PyObject *v) {
    int r;
    if (!j) return -1;
    r = PyObject_SetItem(o, j, v);
    Py_DECREF(j);
    return r;
}
static CYTHON_INLINE int __Pyx_SetItemInt_Fast(PyObject *o, Py_ssize_t i, PyObject *v, int is_list,
                                               CYTHON_NCP_UNUSED int wraparound, CYTHON_NCP_UNUSED int boundscheck) {
#if CYTHON_ASSUME_SAFE_MACROS && !CYTHON_AVOID_BORROWED_REFS && CYTHON_USE_TYPE_SLOTS
    if (is_list || PyList_CheckExact(o)) {
        Py_ssize_t n = (!wraparound) ? i : ((likely(i >= 0)) ? i : i + PyList_GET_SIZE(o));
        if ((!boundscheck) || likely(__Pyx_is_valid_index(n, PyList_GET_SIZE(o)))) {
            PyObject* old = PyList_GET_ITEM(o, n);
            Py_INCREF(v);
            PyList_SET_ITEM(o, n, v);
            Py_DECREF(old);
            return 1;
        }
    } else {
        PySequenceMethods *m = Py_TYPE(o)->tp_as_sequence;
        if (likely(m && m->sq_ass_item)) {
            if (wraparound && unlikely(i < 0) && likely(m->sq_length)) {
                Py_ssize_t l = m->sq_length(o);
                if (likely(l >= 0)) {
                    i += l;
                } else {
                    if (!PyErr_ExceptionMatches(PyExc_OverflowError))
                        return -1;
                    PyErr_Clear();
                }
            }
            return m->sq_ass_item(o, i, v);
        }
    }
#else
#if CYTHON_COMPILING_IN_PYPY
    if (is_list || (PySequence_Check(o) && !PyDict_Check(o)))
#else
    if (is_list || PySequence_Check(o))
#endif
    {
        return PySequence_SetItem(o, i, v);
    }
#endif
    return __Pyx_SetItemInt_Generic(o, PyInt_FromSsize_t(i), v);
}

/* IterFinish */
static CYTHON_INLINE int __Pyx_IterFinish(void) {
#if CYTHON_FAST_THREAD_STATE
    PyThreadState *tstate = __Pyx_PyThreadState_Current;
    PyObject* exc_type = tstate->curexc_type;
    if (unlikely(exc_type)) {
        if (likely(__Pyx_PyErr_GivenExceptionMatches(exc_type, PyExc_StopIteration))) {
            PyObject *exc_value, *exc_tb;
            exc_value = tstate->curexc_value;
            exc_tb = tstate->curexc_traceback;
            tstate->curexc_type = 0;
            tstate->curexc_value = 0;
            tstate->curexc_traceback = 0;
            Py_DECREF(exc_type);
            Py_XDECREF(exc_value);
            Py_XDECREF(exc_tb);
            return 0;
        } else {
            return -1;
        }
    }
    return 0;
#else
    if (unlikely(PyErr_Occurred())) {
        if (likely(PyErr_ExceptionMatches(PyExc_StopIteration))) {
            PyErr_Clear();
            return 0;
        } else {
            return -1;
        }
    }
    return 0;
#endif
}

/* PyObjectCallNoArg */
#if CYTHON_COMPILING_IN_CPYTHON
static CYTHON_INLINE PyObject* __Pyx_PyObject_CallNoArg(PyObject *func) {
#if CYTHON_FAST_PYCALL
    if (PyFunction_Check(func)) {
        return __Pyx_PyFunction_FastCall(func, NULL, 0);
    }
#endif
#ifdef __Pyx_CyFunction_USED
    if (likely(PyCFunction_Check(func) || __Pyx_CyFunction_Check(func)))
#else
    if (likely(PyCFunction_Check(func)))
#endif
    {
        if (likely(PyCFunction_GET_FLAGS(func) & METH_NOARGS)) {
            return __Pyx_PyObject_CallMethO(func, NULL);
        }
    }
    return __Pyx_PyObject_Call(func, __pyx_empty_tuple, NULL);
}
#endif

/* PyObjectGetMethod */
static int __Pyx_PyObject_GetMethod(PyObject *obj, PyObject *name, PyObject **method) {
    PyObject *attr;
#if CYTHON_UNPACK_METHODS && CYTHON_COMPILING_IN_CPYTHON && CYTHON_USE_PYTYPE_LOOKUP
    PyTypeObject *tp = Py_TYPE(obj);
    PyObject *descr;
    descrgetfunc f = NULL;
    PyObject **dictptr, *dict;
    int meth_found = 0;
    assert (*method == NULL);
    if (unlikely(tp->tp_getattro != PyObject_GenericGetAttr)) {
        attr = __Pyx_PyObject_GetAttrStr(obj, name);
        goto try_unpack;
    }
    if (unlikely(tp->tp_dict == NULL) && unlikely(PyType_Ready(tp) < 0)) {
        return 0;
    }
    descr = _PyType_Lookup(tp, name);
    if (likely(descr != NULL)) {
        Py_INCREF(descr);
#if PY_MAJOR_VERSION >= 3
        #ifdef __Pyx_CyFunction_USED
        if (likely(PyFunction_Check(descr) || (Py_TYPE(descr) == &PyMethodDescr_Type) || __Pyx_CyFunction_Check(descr)))
        #else
        if (likely(PyFunction_Check(descr) || (Py_TYPE(descr) == &PyMethodDescr_Type)))
        #endif
#else
        #ifdef __Pyx_CyFunction_USED
        if (likely(PyFunction_Check(descr) || __Pyx_CyFunction_Check(descr)))
        #else
        if (likely(PyFunction_Check(descr)))
        #endif
#endif
        {
            meth_found = 1;
        } else {
            f = Py_TYPE(descr)->tp_descr_get;
            if (f != NULL && PyDescr_IsData(descr)) {
                attr = f(descr, obj, (PyObject *)Py_TYPE(obj));
                Py_DECREF(descr);
                goto try_unpack;
            }
        }
    }
    dictptr = _PyObject_GetDictPtr(obj);
    if (dictptr != NULL && (dict = *dictptr) != NULL) {
        Py_INCREF(dict);
        attr = __Pyx_PyDict_GetItemStr(dict, name);
        if (attr != NULL) {
            Py_INCREF(attr);
            Py_DECREF(dict);
            Py_XDECREF(descr);
            goto try_unpack;
        }
        Py_DECREF(dict);
    }
    if (meth_found) {
        *method = descr;
        return 1;
    }
    if (f != NULL) {
        attr = f(descr, obj, (PyObject *)Py_TYPE(obj));
        Py_DECREF(descr);
        goto try_unpack;
    }
    if (descr != NULL) {
        *method = descr;
        return 0;
    }
    PyErr_Format(PyExc_AttributeError,
#if PY_MAJOR_VERSION >= 3
                 "'%.50s' object has no attribute '%U'",
                 tp->tp_name, name);
#else
                 "'%.50s' object has no attribute '%.400s'",
                 tp->tp_name, PyString_AS_STRING(name));
#endif
    return 0;
#else
    attr = __Pyx_PyObject_GetAttrStr(obj, name);
    goto try_unpack;
#endif
try_unpack:
#if CYTHON_UNPACK_METHODS
    if (likely(attr) && PyMethod_Check(attr) && likely(PyMethod_GET_SELF(attr) == obj)) {
        PyObject *function = PyMethod_GET_FUNCTION(attr);
        Py_INCREF(function);
        Py_DECREF(attr);
        *method = function;
        return 1;
    }
#endif
    *method = attr;
    return 0;
}

/* PyObjectCallMethod0 */
static PyObject* __Pyx_PyObject_CallMethod0(PyObject* obj, PyObject* method_name) {
    PyObject *method = NULL, *result = NULL;
    int is_method = __Pyx_PyObject_GetMethod(obj, method_name, &method);
    if (likely(is_method)) {
        result = __Pyx_PyObject_CallOneArg(method, obj);
        Py_DECREF(method);
        return result;
    }
    if (unlikely(!method)) goto bad;
    result = __Pyx_PyObject_CallNoArg(method);
    Py_DECREF(method);
bad:
    return result;
}

/* RaiseNeedMoreValuesToUnpack */
static CYTHON_INLINE void __Pyx_RaiseNeedMoreValuesError(Py_ssize_t index) {
    PyErr_Format(PyExc_ValueError,
                 "need more than %" CYTHON_FORMAT_SSIZE_T "d value%.1s to unpack",
                 index, (index == 1) ? "" : "s");
}

/* RaiseTooManyValuesToUnpack */
static CYTHON_INLINE void __Pyx_RaiseTooManyValuesError(Py_ssize_t expected) {
    PyErr_Format(PyExc_ValueError,
                 "too many values to unpack (expected %" CYTHON_FORMAT_SSIZE_T "d)", expected);
}

/* UnpackItemEndCheck */
static int __Pyx_IternextUnpackEndCheck(PyObject *retval, Py_ssize_t expected) {
    if (unlikely(retval)) {
        Py_DECREF(retval);
        __Pyx_RaiseTooManyValuesError(expected);
        return -1;
    } else {
        return __Pyx_IterFinish();
    }
    return 0;
}

/* RaiseNoneIterError */
static CYTHON_INLINE void __Pyx_RaiseNoneNotIterableError(void) {
    PyErr_SetString(PyExc_TypeError, "'NoneType' object is not iterable");
}

/* UnpackTupleError */
static void __Pyx_UnpackTupleError(PyObject *t, Py_ssize_t index) {
    if (t == Py_None) {
      __Pyx_RaiseNoneNotIterableError();
    } else if (PyTuple_GET_SIZE(t) < index) {
      __Pyx_RaiseNeedMoreValuesError(PyTuple_GET_SIZE(t));
    } else {
      __Pyx_RaiseTooManyValuesError(index);
    }
}

/* UnpackTuple2 */
static CYTHON_INLINE int __Pyx_unpack_tuple2_exact(
        PyObject* tuple, PyObject** pvalue1, PyObject** pvalue2, int decref_tuple) {
    PyObject *value1 = NULL, *value2 = NULL;
#if CYTHON_COMPILING_IN_PYPY
    value1 = PySequence_ITEM(tuple, 0);  if (unlikely(!value1)) goto bad;
    value2 = PySequence_ITEM(tuple, 1);  if (unlikely(!value2)) goto bad;
#else
    value1 = PyTuple_GET_ITEM(tuple, 0);  Py_INCREF(value1);
    value2 = PyTuple_GET_ITEM(tuple, 1);  Py_INCREF(value2);
#endif
    if (decref_tuple) {
        Py_DECREF(tuple);
    }
    *pvalue1 = value1;
    *pvalue2 = value2;
    return 0;
#if CYTHON_COMPILING_IN_PYPY
bad:
    Py_XDECREF(value1);
    Py_XDECREF(value2);
    if (decref_tuple) { Py_XDECREF(tuple); }
    return -1;
#endif
}
static int __Pyx_unpack_tuple2_generic(PyObject* tuple, PyObject** pvalue1, PyObject** pvalue2,
                                       int has_known_size, int decref_tuple) {
    Py_ssize_t index;
    PyObject *value1 = NULL, *value2 = NULL, *iter = NULL;
    iternextfunc iternext;
    iter = PyObject_GetIter(tuple);
    if (unlikely(!iter)) goto bad;
    if (decref_tuple) { Py_DECREF(tuple); tuple = NULL; }
    iternext = Py_TYPE(iter)->tp_iternext;
    value1 = iternext(iter); if (unlikely(!value1)) { index = 0; goto unpacking_failed; }
    value2 = iternext(iter); if (unlikely(!value2)) { index = 1; goto unpacking_failed; }
    if (!has_known_size && unlikely(__Pyx_IternextUnpackEndCheck(iternext(iter), 2))) goto bad;
    Py_DECREF(iter);
    *pvalue1 = value1;
    *pvalue2 = value2;
    return 0;
unpacking_failed:
    if (!has_known_size && __Pyx_IterFinish() == 0)
        __Pyx_RaiseNeedMoreValuesError(index);
bad:
    Py_XDECREF(iter);
    Py_XDECREF(value1);
    Py_XDECREF(value2);
    if (decref_tuple) { Py_XDECREF(tuple); }
    return -1;
}

/* dict_iter */
static CYTHON_INLINE PyObject* __Pyx_dict_iterator(PyObject* iterable, int is_dict, PyObject* method_name,
                                                   Py_ssize_t* p_orig_length, int* p_source_is_dict) {
    is_dict = is_dict || likely(PyDict_CheckExact(iterable));
    *p_source_is_dict = is_dict;
    if (is_dict) {
#if !CYTHON_COMPILING_IN_PYPY
        *p_orig_length = PyDict_Size(iterable);
        Py_INCREF(iterable);
        return iterable;
#elif PY_MAJOR_VERSION >= 3
        static PyObject *py_items = NULL, *py_keys = NULL, *py_values = NULL;
        PyObject **pp = NULL;
        if (method_name) {
            const char *name = PyUnicode_AsUTF8(method_name);
            if (strcmp(name, "iteritems") == 0) pp = &py_items;
            else if (strcmp(name, "iterkeys") == 0) pp = &py_keys;
            else if (strcmp(name, "itervalues") == 0) pp = &py_values;
            if (pp) {
                if (!*pp) {
                    *pp = PyUnicode_FromString(name + 4);
                    if (!*pp)
                        return NULL;
                }
                method_name = *pp;
            }
        }
#endif
    }
    *p_orig_length = 0;
    if (method_name) {
        PyObject* iter;
        iterable = __Pyx_PyObject_CallMethod0(iterable, method_name);
        if (!iterable)
            return NULL;
#if !CYTHON_COMPILING_IN_PYPY
        if (PyTuple_CheckExact(iterable) || PyList_CheckExact(iterable))
            return iterable;
#endif
        iter = PyObject_GetIter(iterable);
        Py_DECREF(iterable);
        return iter;
    }
    return PyObject_GetIter(iterable);
}
static CYTHON_INLINE int __Pyx_dict_iter_next(
        PyObject* iter_obj, CYTHON_NCP_UNUSED Py_ssize_t orig_length, CYTHON_NCP_UNUSED Py_ssize_t* ppos,
        PyObject** pkey, PyObject** pvalue, PyObject** pitem, int source_is_dict) {
    PyObject* next_item;
#if !CYTHON_COMPILING_IN_PYPY
    if (source_is_dict) {
        PyObject *key, *value;
        if (unlikely(orig_length != PyDict_Size(iter_obj))) {
            PyErr_SetString(PyExc_RuntimeError, "dictionary changed size during iteration");
            return -1;
        }
        if (unlikely(!PyDict_Next(iter_obj, ppos, &key, &value))) {
            return 0;
        }
        if (pitem) {
            PyObject* tuple = PyTuple_New(2);
            if (unlikely(!tuple)) {
                return -1;
            }
            Py_INCREF(key);
            Py_INCREF(value);
            PyTuple_SET_ITEM(tuple, 0, key);
            PyTuple_SET_ITEM(tuple, 1, value);
            *pitem = tuple;
        } else {
            if (pkey) {
                Py_INCREF(key);
                *pkey = key;
            }
            if (pvalue) {
                Py_INCREF(value);
                *pvalue = value;
            }
        }
        return 1;
    } else if (PyTuple_CheckExact(iter_obj)) {
        Py_ssize_t pos = *ppos;
        if (unlikely(pos >= PyTuple_GET_SIZE(iter_obj))) return 0;
        *ppos = pos + 1;
        next_item = PyTuple_GET_ITEM(iter_obj, pos);
        Py_INCREF(next_item);
    } else if (PyList_CheckExact(iter_obj)) {
        Py_ssize_t pos = *ppos;
        if (unlikely(pos >= PyList_GET_SIZE(iter_obj))) return 0;
        *ppos = pos + 1;
        next_item = PyList_GET_ITEM(iter_obj, pos);
        Py_INCREF(next_item);
    } else
#endif
    {
        next_item = PyIter_Next(iter_obj);
        if (unlikely(!next_item)) {
            return __Pyx_IterFinish();
        }
    }
    if (pitem) {
        *pitem = next_item;
    } else if (pkey && pvalue) {
        if (__Pyx_unpack_tuple2(next_item, pkey, pvalue, source_is_dict, source_is_dict, 1))
            return -1;
    } else if (pkey) {
        *pkey = next_item;
    } else {
        *pvalue = next_item;
    }
    return 1;
}

/* PyObjectCall2Args */
static CYTHON_UNUSED PyObject* __Pyx_PyObject_Call2Args(PyObject* function, PyObject* arg1, PyObject* arg2) {
    PyObject *args, *result = NULL;
    #if CYTHON_FAST_PYCALL
    if (PyFunction_Check(function)) {
        PyObject *args[2] = {arg1, arg2};
        return __Pyx_PyFunction_FastCall(function, args, 2);
    }
    #endif
    #if CYTHON_FAST_PYCCALL
    if (__Pyx_PyFastCFunction_Check(function)) {
        PyObject *args[2] = {arg1, arg2};
        return __Pyx_PyCFunction_FastCall(function, args, 2);
    }
    #endif
    args = PyTuple_New(2);
    if (unlikely(!args)) goto done;
    Py_INCREF(arg1);
    PyTuple_SET_ITEM(args, 0, arg1);
    Py_INCREF(arg2);
    PyTuple_SET_ITEM(args, 1, arg2);
    Py_INCREF(function);
    result = __Pyx_PyObject_Call(function, args, NULL);
    Py_DECREF(args);
    Py_DECREF(function);
done:
    return result;
}

/* GetItemInt */
static PyObject *__Pyx_GetItemInt_Generic(PyObject *o, PyObject* j) {
    PyObject *r;
    if (!j) return NULL;
    r = PyObject_GetItem(o, j);
    Py_DECREF(j);
    return r;
}
static CYTHON_INLINE PyObject *__Pyx_GetItemInt_List_Fast(PyObject *o, Py_ssize_t i,
                                                              CYTHON_NCP_UNUSED int wraparound,
                                                              CYTHON_NCP_UNUSED int boundscheck) {
#if CYTHON_ASSUME_SAFE_MACROS && !CYTHON_AVOID_BORROWED_REFS
    Py_ssize_t wrapped_i = i;
    if (wraparound & unlikely(i < 0)) {
        wrapped_i += PyList_GET_SIZE(o);
    }
    if ((!boundscheck) || likely(__Pyx_is_valid_index(wrapped_i, PyList_GET_SIZE(o)))) {
        PyObject *r = PyList_GET_ITEM(o, wrapped_i);
        Py_INCREF(r);
        return r;
    }
    return __Pyx_GetItemInt_Generic(o, PyInt_FromSsize_t(i));
#else
    return PySequence_GetItem(o, i);
#endif
}
static CYTHON_INLINE PyObject *__Pyx_GetItemInt_Tuple_Fast(PyObject *o, Py_ssize_t i,
                                                              CYTHON_NCP_UNUSED int wraparound,
                                                              CYTHON_NCP_UNUSED int boundscheck) {
#if CYTHON_ASSUME_SAFE_MACROS && !CYTHON_AVOID_BORROWED_REFS
    Py_ssize_t wrapped_i = i;
    if (wraparound & unlikely(i < 0)) {
        wrapped_i += PyTuple_GET_SIZE(o);
    }
    if ((!boundscheck) || likely(__Pyx_is_valid_index(wrapped_i, PyTuple_GET_SIZE(o)))) {
        PyObject *r = PyTuple_GET_ITEM(o, wrapped_i);
        Py_INCREF(r);
        return r;
    }
    return __Pyx_GetItemInt_Generic(o, PyInt_FromSsize_t(i));
#else
    return PySequence_GetItem(o, i);
#endif
}
static CYTHON_INLINE PyObject *__Pyx_GetItemInt_Fast(PyObject *o, Py_ssize_t i, int is_list,
                                                     CYTHON_NCP_UNUSED int wraparound,
                                                     CYTHON_NCP_UNUSED int boundscheck) {
#if CYTHON_ASSUME_SAFE_MACROS && !CYTHON_AVOID_BORROWED_REFS && CYTHON_USE_TYPE_SLOTS
    if (is_list || PyList_CheckExact(o)) {
        Py_ssize_t n = ((!wraparound) | likely(i >= 0)) ? i : i + PyList_GET_SIZE(o);
        if ((!boundscheck) || (likely(__Pyx_is_valid_index(n, PyList_GET_SIZE(o))))) {
            PyObject *r = PyList_GET_ITEM(o, n);
            Py_INCREF(r);
            return r;
        }
    }
    else if (PyTuple_CheckExact(o)) {
        Py_ssize_t n = ((!wraparound) | likely(i >= 0)) ? i : i + PyTuple_GET_SIZE(o);
        if ((!boundscheck) || likely(__Pyx_is_valid_index(n, PyTuple_GET_SIZE(o)))) {
            PyObject *r = PyTuple_GET_ITEM(o, n);
            Py_INCREF(r);
            return r;
        }
    } else {
        PySequenceMethods *m = Py_TYPE(o)->tp_as_sequence;
        if (likely(m && m->sq_item)) {
            if (wraparound && unlikely(i < 0) && likely(m->sq_length)) {
                Py_ssize_t l = m->sq_length(o);
                if (likely(l >= 0)) {
                    i += l;
                } else {
                    if (!PyErr_ExceptionMatches(PyExc_OverflowError))
                        return NULL;
                    PyErr_Clear();
                }
            }
            return m->sq_item(o, i);
        }
    }
#else
    if (is_list || PySequence_Check(o)) {
        return PySequence_GetItem(o, i);
    }
#endif
    return __Pyx_GetItemInt_Generic(o, PyInt_FromSsize_t(i));
}

/* IsLittleEndian */
static CYTHON_INLINE int __Pyx_Is_Little_Endian(void)
{
  union {
    uint32_t u32;
    uint8_t u8[4];
  } S;
  S.u32 = 0x01020304;
  return S.u8[0] == 4;
}

/* BufferFormatCheck */
static void __Pyx_BufFmt_Init(__Pyx_BufFmt_Context* ctx,
                              __Pyx_BufFmt_StackElem* stack,
                              __Pyx_TypeInfo* type) {
  stack[0].field = &ctx->root;
  stack[0].parent_offset = 0;
  ctx->root.type = type;
  ctx->root.name = "buffer dtype";
  ctx->root.offset = 0;
  ctx->head = stack;
  ctx->head->field = &ctx->root;
  ctx->fmt_offset = 0;
  ctx->head->parent_offset = 0;
  ctx->new_packmode = '@';
  ctx->enc_packmode = '@';
  ctx->new_count = 1;
  ctx->enc_count = 0;
  ctx->enc_type = 0;
  ctx->is_complex = 0;
  ctx->is_valid_array = 0;
  ctx->struct_alignment = 0;
  while (type->typegroup == 'S') {
    ++ctx->head;
    ctx->head->field = type->fields;
    ctx->head->parent_offset = 0;
    type = type->fields->type;
  }
}
static int __Pyx_BufFmt_ParseNumber(const char** ts) {
    int count;
    const char* t = *ts;
    if (*t < '0' || *t > '9') {
      return -1;
    } else {
        count = *t++ - '0';
        while (*t >= '0' && *t <= '9') {
            count *= 10;
            count += *t++ - '0';
        }
    }
    *ts = t;
    return count;
}
static int __Pyx_BufFmt_ExpectNumber(const char **ts) {
    int number = __Pyx_BufFmt_ParseNumber(ts);
    if (number == -1)
        PyErr_Format(PyExc_ValueError,\
                     "Does not understand character buffer dtype format string ('%c')", **ts);
    return number;
}
static void __Pyx_BufFmt_RaiseUnexpectedChar(char ch) {
  PyErr_Format(PyExc_ValueError,
               "Unexpected format string character: '%c'", ch);
}
static const char* __Pyx_BufFmt_DescribeTypeChar(char ch, int is_complex) {
  switch (ch) {
    case '?': return "'bool'";
    case 'c': return "'char'";
    case 'b': return "'signed char'";
    case 'B': return "'unsigned char'";
    case 'h': return "'short'";
    case 'H': return "'unsigned short'";
    case 'i': return "'int'";
    case 'I': return "'unsigned int'";
    case 'l': return "'long'";
    case 'L': return "'unsigned long'";
    case 'q': return "'long long'";
    case 'Q': return "'unsigned long long'";
    case 'f': return (is_complex ? "'complex float'" : "'float'");
    case 'd': return (is_complex ? "'complex double'" : "'double'");
    case 'g': return (is_complex ? "'complex long double'" : "'long double'");
    case 'T': return "a struct";
    case 'O': return "Python object";
    case 'P': return "a pointer";
    case 's': case 'p': return "a string";
    case 0: return "end";
    default: return "unparseable format string";
  }
}
static size_t __Pyx_BufFmt_TypeCharToStandardSize(char ch, int is_complex) {
  switch (ch) {
    case '?': case 'c': case 'b': case 'B': case 's': case 'p': return 1;
    case 'h': case 'H': return 2;
    case 'i': case 'I': case 'l': case 'L': return 4;
    case 'q': case 'Q': return 8;
    case 'f': return (is_complex ? 8 : 4);
    case 'd': return (is_complex ? 16 : 8);
    case 'g': {
      PyErr_SetString(PyExc_ValueError, "Python does not define a standard format string size for long double ('g')..");
      return 0;
    }
    case 'O': case 'P': return sizeof(void*);
    default:
      __Pyx_BufFmt_RaiseUnexpectedChar(ch);
      return 0;
    }
}
static size_t __Pyx_BufFmt_TypeCharToNativeSize(char ch, int is_complex) {
  switch (ch) {
    case '?': case 'c': case 'b': case 'B': case 's': case 'p': return 1;
    case 'h': case 'H': return sizeof(short);
    case 'i': case 'I': return sizeof(int);
    case 'l': case 'L': return sizeof(long);
    #ifdef HAVE_LONG_LONG
    case 'q': case 'Q': return sizeof(PY_LONG_LONG);
    #endif
    case 'f': return sizeof(float) * (is_complex ? 2 : 1);
    case 'd': return sizeof(double) * (is_complex ? 2 : 1);
    case 'g': return sizeof(long double) * (is_complex ? 2 : 1);
    case 'O': case 'P': return sizeof(void*);
    default: {
      __Pyx_BufFmt_RaiseUnexpectedChar(ch);
      return 0;
    }
  }
}
typedef struct { char c; short x; } __Pyx_st_short;
typedef struct { char c; int x; } __Pyx_st_int;
typedef struct { char c; long x; } __Pyx_st_long;
typedef struct { char c; float x; } __Pyx_st_float;
typedef struct { char c; double x; } __Pyx_st_double;
typedef struct { char c; long double x; } __Pyx_st_longdouble;
typedef struct { char c; void *x; } __Pyx_st_void_p;
#ifdef HAVE_LONG_LONG
typedef struct { char c; PY_LONG_LONG x; } __Pyx_st_longlong;
#endif
static size_t __Pyx_BufFmt_TypeCharToAlignment(char ch, CYTHON_UNUSED int is_complex) {
  switch (ch) {
    case '?': case 'c': case 'b': case 'B': case 's': case 'p': return 1;
    case 'h': case 'H': return sizeof(__Pyx_st_short) - sizeof(short);
    case 'i': case 'I': return sizeof(__Pyx_st_int) - sizeof(int);
    case 'l': case 'L': return sizeof(__Pyx_st_long) - sizeof(long);
#ifdef HAVE_LONG_LONG
    case 'q': case 'Q': return sizeof(__Pyx_st_longlong) - sizeof(PY_LONG_LONG);
#endif
    case 'f': return sizeof(__Pyx_st_float) - sizeof(float);
    case 'd': return sizeof(__Pyx_st_double) - sizeof(double);
    case 'g': return sizeof(__Pyx_st_longdouble) - sizeof(long double);
    case 'P': case 'O': return sizeof(__Pyx_st_void_p) - sizeof(void*);
    default:
      __Pyx_BufFmt_RaiseUnexpectedChar(ch);
      return 0;
    }
}
/* These are for computing the padding at the end of the struct to align
   on the first member of the struct. This will probably the same as above,
   but we don't have any guarantees.
 */
typedef struct { short x; char c; } __Pyx_pad_short;
typedef struct { int x; char c; } __Pyx_pad_int;
typedef struct { long x; char c; } __Pyx_pad_long;
typedef struct { float x; char c; } __Pyx_pad_float;
typedef struct { double x; char c; } __Pyx_pad_double;
typedef struct { long double x; char c; } __Pyx_pad_longdouble;
typedef struct { void *x; char c; } __Pyx_pad_void_p;
#ifdef HAVE_LONG_LONG
typedef struct { PY_LONG_LONG x; char c; } __Pyx_pad_longlong;
#endif
static size_t __Pyx_BufFmt_TypeCharToPadding(char ch, CYTHON_UNUSED int is_complex) {
  switch (ch) {
    case '?': case 'c': case 'b': case 'B': case 's': case 'p': return 1;
    case 'h': case 'H': return sizeof(__Pyx_pad_short) - sizeof(short);
    case 'i': case 'I': return sizeof(__Pyx_pad_int) - sizeof(int);
    case 'l': case 'L': return sizeof(__Pyx_pad_long) - sizeof(long);
#ifdef HAVE_LONG_LONG
    case 'q': case 'Q': return sizeof(__Pyx_pad_longlong) - sizeof(PY_LONG_LONG);
#endif
    case 'f': return sizeof(__Pyx_pad_float) - sizeof(float);
    case 'd': return sizeof(__Pyx_pad_double) - sizeof(double);
    case 'g': return sizeof(__Pyx_pad_longdouble) - sizeof(long double);
    case 'P': case 'O': return sizeof(__Pyx_pad_void_p) - sizeof(void*);
    default:
      __Pyx_BufFmt_RaiseUnexpectedChar(ch);
      return 0;
    }
}
static char __Pyx_BufFmt_TypeCharToGroup(char ch, int is_complex) {
  switch (ch) {
    case 'c':
        return 'H';
    case 'b': case 'h': case 'i':
    case 'l': case 'q': case 's': case 'p':
        return 'I';
    case '?': case 'B': case 'H': case 'I': case 'L': case 'Q':
        return 'U';
    case 'f': case 'd': case 'g':
        return (is_complex ? 'C' : 'R');
    case 'O':
        return 'O';
    case 'P':
        return 'P';
    default: {
      __Pyx_BufFmt_RaiseUnexpectedChar(ch);
      return 0;
    }
  }
}
static void __Pyx_BufFmt_RaiseExpected(__Pyx_BufFmt_Context* ctx) {
  if (ctx->head == NULL || ctx->head->field == &ctx->root) {
    const char* expected;
    const char* quote;
    if (ctx->head == NULL) {
      expected = "end";
      quote = "";
    } else {
      expected = ctx->head->field->type->name;
      quote = "'";
    }
    PyErr_Format(PyExc_ValueError,
                 "Buffer dtype mismatch, expected %s%s%s but got %s",
                 quote, expected, quote,
                 __Pyx_BufFmt_DescribeTypeChar(ctx->enc_type, ctx->is_complex));
  } else {
    __Pyx_StructField* field = ctx->head->field;
    __Pyx_StructField* parent = (ctx->head - 1)->field;
    PyErr_Format(PyExc_ValueError,
                 "Buffer dtype mismatch, expected '%s' but got %s in '%s.%s'",
                 field->type->name, __Pyx_BufFmt_DescribeTypeChar(ctx->enc_type, ctx->is_complex),
                 parent->type->name, field->name);
  }
}
static int __Pyx_BufFmt_ProcessTypeChunk(__Pyx_BufFmt_Context* ctx) {
  char group;
  size_t size, offset, arraysize = 1;
  if (ctx->enc_type == 0) return 0;
  if (ctx->head->field->type->arraysize[0]) {
    int i, ndim = 0;
    if (ctx->enc_type == 's' || ctx->enc_type == 'p') {
        ctx->is_valid_array = ctx->head->field->type->ndim == 1;
        ndim = 1;
        if (ctx->enc_count != ctx->head->field->type->arraysize[0]) {
            PyErr_Format(PyExc_ValueError,
                         "Expected a dimension of size %zu, got %zu",
                         ctx->head->field->type->arraysize[0], ctx->enc_count);
            return -1;
        }
    }
    if (!ctx->is_valid_array) {
      PyErr_Format(PyExc_ValueError, "Expected %d dimensions, got %d",
                   ctx->head->field->type->ndim, ndim);
      return -1;
    }
    for (i = 0; i < ctx->head->field->type->ndim; i++) {
      arraysize *= ctx->head->field->type->arraysize[i];
    }
    ctx->is_valid_array = 0;
    ctx->enc_count = 1;
  }
  group = __Pyx_BufFmt_TypeCharToGroup(ctx->enc_type, ctx->is_complex);
  do {
    __Pyx_StructField* field = ctx->head->field;
    __Pyx_TypeInfo* type = field->type;
    if (ctx->enc_packmode == '@' || ctx->enc_packmode == '^') {
      size = __Pyx_BufFmt_TypeCharToNativeSize(ctx->enc_type, ctx->is_complex);
    } else {
      size = __Pyx_BufFmt_TypeCharToStandardSize(ctx->enc_type, ctx->is_complex);
    }
    if (ctx->enc_packmode == '@') {
      size_t align_at = __Pyx_BufFmt_TypeCharToAlignment(ctx->enc_type, ctx->is_complex);
      size_t align_mod_offset;
      if (align_at == 0) return -1;
      align_mod_offset = ctx->fmt_offset % align_at;
      if (align_mod_offset > 0) ctx->fmt_offset += align_at - align_mod_offset;
      if (ctx->struct_alignment == 0)
          ctx->struct_alignment = __Pyx_BufFmt_TypeCharToPadding(ctx->enc_type,
                                                                 ctx->is_complex);
    }
    if (type->size != size || type->typegroup != group) {
      if (type->typegroup == 'C' && type->fields != NULL) {
        size_t parent_offset = ctx->head->parent_offset + field->offset;
        ++ctx->head;
        ctx->head->field = type->fields;
        ctx->head->parent_offset = parent_offset;
        continue;
      }
      if ((type->typegroup == 'H' || group == 'H') && type->size == size) {
      } else {
          __Pyx_BufFmt_RaiseExpected(ctx);
          return -1;
      }
    }
    offset = ctx->head->parent_offset + field->offset;
    if (ctx->fmt_offset != offset) {
      PyErr_Format(PyExc_ValueError,
                   "Buffer dtype mismatch; next field is at offset %" CYTHON_FORMAT_SSIZE_T "d but %" CYTHON_FORMAT_SSIZE_T "d expected",
                   (Py_ssize_t)ctx->fmt_offset, (Py_ssize_t)offset);
      return -1;
    }
    ctx->fmt_offset += size;
    if (arraysize)
      ctx->fmt_offset += (arraysize - 1) * size;
    --ctx->enc_count;
    while (1) {
      if (field == &ctx->root) {
        ctx->head = NULL;
        if (ctx->enc_count != 0) {
          __Pyx_BufFmt_RaiseExpected(ctx);
          return -1;
        }
        break;
      }
      ctx->head->field = ++field;
      if (field->type == NULL) {
        --ctx->head;
        field = ctx->head->field;
        continue;
      } else if (field->type->typegroup == 'S') {
        size_t parent_offset = ctx->head->parent_offset + field->offset;
        if (field->type->fields->type == NULL) continue;
        field = field->type->fields;
        ++ctx->head;
        ctx->head->field = field;
        ctx->head->parent_offset = parent_offset;
        break;
      } else {
        break;
      }
    }
  } while (ctx->enc_count);
  ctx->enc_type = 0;
  ctx->is_complex = 0;
  return 0;
}
static PyObject *
__pyx_buffmt_parse_array(__Pyx_BufFmt_Context* ctx, const char** tsp)
{
    const char *ts = *tsp;
    int i = 0, number;
    int ndim = ctx->head->field->type->ndim;
;
    ++ts;
    if (ctx->new_count != 1) {
        PyErr_SetString(PyExc_ValueError,
                        "Cannot handle repeated arrays in format string");
        return NULL;
    }
    if (__Pyx_BufFmt_ProcessTypeChunk(ctx) == -1) return NULL;
    while (*ts && *ts != ')') {
        switch (*ts) {
            case ' ': case '\f': case '\r': case '\n': case '\t': case '\v':  continue;
            default:  break;
        }
        number = __Pyx_BufFmt_ExpectNumber(&ts);
        if (number == -1) return NULL;
        if (i < ndim && (size_t) number != ctx->head->field->type->arraysize[i])
            return PyErr_Format(PyExc_ValueError,
                        "Expected a dimension of size %zu, got %d",
                        ctx->head->field->type->arraysize[i], number);
        if (*ts != ',' && *ts != ')')
            return PyErr_Format(PyExc_ValueError,
                                "Expected a comma in format string, got '%c'", *ts);
        if (*ts == ',') ts++;
        i++;
    }
    if (i != ndim)
        return PyErr_Format(PyExc_ValueError, "Expected %d dimension(s), got %d",
                            ctx->head->field->type->ndim, i);
    if (!*ts) {
        PyErr_SetString(PyExc_ValueError,
                        "Unexpected end of format string, expected ')'");
        return NULL;
    }
    ctx->is_valid_array = 1;
    ctx->new_count = 1;
    *tsp = ++ts;
    return Py_None;
}
static const char* __Pyx_BufFmt_CheckString(__Pyx_BufFmt_Context* ctx, const char* ts) {
  int got_Z = 0;
  while (1) {
    switch(*ts) {
      case 0:
        if (ctx->enc_type != 0 && ctx->head == NULL) {
          __Pyx_BufFmt_RaiseExpected(ctx);
          return NULL;
        }
        if (__Pyx_BufFmt_ProcessTypeChunk(ctx) == -1) return NULL;
        if (ctx->head != NULL) {
          __Pyx_BufFmt_RaiseExpected(ctx);
          return NULL;
        }
        return ts;
      case ' ':
      case '\r':
      case '\n':
        ++ts;
        break;
      case '<':
        if (!__Pyx_Is_Little_Endian()) {
          PyErr_SetString(PyExc_ValueError, "Little-endian buffer not supported on big-endian compiler");
          return NULL;
        }
        ctx->new_packmode = '=';
        ++ts;
        break;
      case '>':
      case '!':
        if (__Pyx_Is_Little_Endian()) {
          PyErr_SetString(PyExc_ValueError, "Big-endian buffer not supported on little-endian compiler");
          return NULL;
        }
        ctx->new_packmode = '=';
        ++ts;
        break;
      case '=':
      case '@':
      case '^':
        ctx->new_packmode = *ts++;
        break;
      case 'T':
        {
          const char* ts_after_sub;
          size_t i, struct_count = ctx->new_count;
          size_t struct_alignment = ctx->struct_alignment;
          ctx->new_count = 1;
          ++ts;
          if (*ts != '{') {
            PyErr_SetString(PyExc_ValueError, "Buffer acquisition: Expected '{' after 'T'");
            return NULL;
          }
          if (__Pyx_BufFmt_ProcessTypeChunk(ctx) == -1) return NULL;
          ctx->enc_type = 0;
          ctx->enc_count = 0;
          ctx->struct_alignment = 0;
          ++ts;
          ts_after_sub = ts;
          for (i = 0; i != struct_count; ++i) {
            ts_after_sub = __Pyx_BufFmt_CheckString(ctx, ts);
            if (!ts_after_sub) return NULL;
          }
          ts = ts_after_sub;
          if (struct_alignment) ctx->struct_alignment = struct_alignment;
        }
        break;
      case '}':
        {
          size_t alignment = ctx->struct_alignment;
          ++ts;
          if (__Pyx_BufFmt_ProcessTypeChunk(ctx) == -1) return NULL;
          ctx->enc_type = 0;
          if (alignment && ctx->fmt_offset % alignment) {
            ctx->fmt_offset += alignment - (ctx->fmt_offset % alignment);
          }
        }
        return ts;
      case 'x':
        if (__Pyx_BufFmt_ProcessTypeChunk(ctx) == -1) return NULL;
        ctx->fmt_offset += ctx->new_count;
        ctx->new_count = 1;
        ctx->enc_count = 0;
        ctx->enc_type = 0;
        ctx->enc_packmode = ctx->new_packmode;
        ++ts;
        break;
      case 'Z':
        got_Z = 1;
        ++ts;
        if (*ts != 'f' && *ts != 'd' && *ts != 'g') {
          __Pyx_BufFmt_RaiseUnexpectedChar('Z');
          return NULL;
        }
        CYTHON_FALLTHROUGH;
      case '?': case 'c': case 'b': case 'B': case 'h': case 'H': case 'i': case 'I':
      case 'l': case 'L': case 'q': case 'Q':
      case 'f': case 'd': case 'g':
      case 'O': case 'p':
        if (ctx->enc_type == *ts && got_Z == ctx->is_complex &&
            ctx->enc_packmode == ctx->new_packmode) {
          ctx->enc_count += ctx->new_count;
          ctx->new_count = 1;
          got_Z = 0;
          ++ts;
          break;
        }
        CYTHON_FALLTHROUGH;
      case 's':
        if (__Pyx_BufFmt_ProcessTypeChunk(ctx) == -1) return NULL;
        ctx->enc_count = ctx->new_count;
        ctx->enc_packmode = ctx->new_packmode;
        ctx->enc_type = *ts;
        ctx->is_complex = got_Z;
        ++ts;
        ctx->new_count = 1;
        got_Z = 0;
        break;
      case ':':
        ++ts;
        while(*ts != ':') ++ts;
        ++ts;
        break;
      case '(':
        if (!__pyx_buffmt_parse_array(ctx, &ts)) return NULL;
        break;
      default:
        {
          int number = __Pyx_BufFmt_ExpectNumber(&ts);
          if (number == -1) return NULL;
          ctx->new_count = (size_t)number;
        }
    }
  }
}

/* BufferGetAndValidate */
  static CYTHON_INLINE void __Pyx_SafeReleaseBuffer(Py_buffer* info) {
  if (unlikely(info->buf == NULL)) return;
  if (info->suboffsets == __Pyx_minusones) info->suboffsets = NULL;
  __Pyx_ReleaseBuffer(info);
}
static void __Pyx_ZeroBuffer(Py_buffer* buf) {
  buf->buf = NULL;
  buf->obj = NULL;
  buf->strides = __Pyx_zeros;
  buf->shape = __Pyx_zeros;
  buf->suboffsets = __Pyx_minusones;
}
static int __Pyx__GetBufferAndValidate(
        Py_buffer* buf, PyObject* obj,  __Pyx_TypeInfo* dtype, int flags,
        int nd, int cast, __Pyx_BufFmt_StackElem* stack)
{
  buf->buf = NULL;
  if (unlikely(__Pyx_GetBuffer(obj, buf, flags) == -1)) {
    __Pyx_ZeroBuffer(buf);
    return -1;
  }
  if (unlikely(buf->ndim != nd)) {
    PyErr_Format(PyExc_ValueError,
                 "Buffer has wrong number of dimensions (expected %d, got %d)",
                 nd, buf->ndim);
    goto fail;
  }
  if (!cast) {
    __Pyx_BufFmt_Context ctx;
    __Pyx_BufFmt_Init(&ctx, stack, dtype);
    if (!__Pyx_BufFmt_CheckString(&ctx, buf->format)) goto fail;
  }
  if (unlikely((size_t)buf->itemsize != dtype->size)) {
    PyErr_Format(PyExc_ValueError,
      "Item size of buffer (%" CYTHON_FORMAT_SSIZE_T "d byte%s) does not match size of '%s' (%" CYTHON_FORMAT_SSIZE_T "d byte%s)",
      buf->itemsize, (buf->itemsize > 1) ? "s" : "",
      dtype->name, (Py_ssize_t)dtype->size, (dtype->size > 1) ? "s" : "");
    goto fail;
  }
  if (buf->suboffsets == NULL) buf->suboffsets = __Pyx_minusones;
  return 0;
fail:;
  __Pyx_SafeReleaseBuffer(buf);
  return -1;
}

/* BufferFallbackError */
  static void __Pyx_RaiseBufferFallbackError(void) {
  PyErr_SetString(PyExc_ValueError,
     "Buffer acquisition failed on assignment; and then reacquiring the old buffer failed too!");
}

/* pyfrozenset_new */
  static CYTHON_INLINE PyObject* __Pyx_PyFrozenSet_New(PyObject* it) {
    if (it) {
        PyObject* result;
#if CYTHON_COMPILING_IN_PYPY
        PyObject* args;
        args = PyTuple_Pack(1, it);
        if (unlikely(!args))
            return NULL;
        result = PyObject_Call((PyObject*)&PyFrozenSet_Type, args, NULL);
        Py_DECREF(args);
        return result;
#else
        if (PyFrozenSet_CheckExact(it)) {
            Py_INCREF(it);
            return it;
        }
        result = PyFrozenSet_New(it);
        if (unlikely(!result))
            return NULL;
        if (likely(PySet_GET_SIZE(result)))
            return result;
        Py_DECREF(result);
#endif
    }
#if CYTHON_USE_TYPE_SLOTS
    return PyFrozenSet_Type.tp_new(&PyFrozenSet_Type, __pyx_empty_tuple, NULL);
#else
    return PyObject_Call((PyObject*)&PyFrozenSet_Type, __pyx_empty_tuple, NULL);
#endif
}

/* PySetContains */
  static int __Pyx_PySet_ContainsUnhashable(PyObject *set, PyObject *key) {
    int result = -1;
    if (PySet_Check(key) && PyErr_ExceptionMatches(PyExc_TypeError)) {
        PyObject *tmpkey;
        PyErr_Clear();
        tmpkey = __Pyx_PyFrozenSet_New(key);
        if (tmpkey != NULL) {
            result = PySet_Contains(set, tmpkey);
            Py_DECREF(tmpkey);
        }
    }
    return result;
}
static CYTHON_INLINE int __Pyx_PySet_ContainsTF(PyObject* key, PyObject* set, int eq) {
    int result = PySet_Contains(set, key);
    if (unlikely(result < 0)) {
        result = __Pyx_PySet_ContainsUnhashable(set, key);
    }
    return unlikely(result < 0) ? result : (result == (eq == Py_EQ));
}

/* None */
  static CYTHON_INLINE void __Pyx_RaiseUnboundLocalError(const char *varname) {
    PyErr_Format(PyExc_UnboundLocalError, "local variable '%s' referenced before assignment", varname);
}

/* Import */
  static PyObject *__Pyx_Import(PyObject *name, PyObject *from_list, int level) {
    PyObject *empty_list = 0;
    PyObject *module = 0;
    PyObject *global_dict = 0;
    PyObject *empty_dict = 0;
    PyObject *list;
    #if PY_MAJOR_VERSION < 3
    PyObject *py_import;
    py_import = __Pyx_PyObject_GetAttrStr(__pyx_b, __pyx_n_s_import);
    if (!py_import)
        goto bad;
    #endif
    if (from_list)
        list = from_list;
    else {
        empty_list = PyList_New(0);
        if (!empty_list)
            goto bad;
        list = empty_list;
    }
    global_dict = PyModule_GetDict(__pyx_m);
    if (!global_dict)
        goto bad;
    empty_dict = PyDict_New();
    if (!empty_dict)
        goto bad;
    {
        #if PY_MAJOR_VERSION >= 3
        if (level == -1) {
            if (strchr(__Pyx_MODULE_NAME, '.')) {
                module = PyImport_ImportModuleLevelObject(
                    name, global_dict, empty_dict, list, 1);
                if (!module) {
                    if (!PyErr_ExceptionMatches(PyExc_ImportError))
                        goto bad;
                    PyErr_Clear();
                }
            }
            level = 0;
        }
        #endif
        if (!module) {
            #if PY_MAJOR_VERSION < 3
            PyObject *py_level = PyInt_FromLong(level);
            if (!py_level)
                goto bad;
            module = PyObject_CallFunctionObjArgs(py_import,
                name, global_dict, empty_dict, list, py_level, (PyObject *)NULL);
            Py_DECREF(py_level);
            #else
            module = PyImport_ImportModuleLevelObject(
                name, global_dict, empty_dict, list, level);
            #endif
        }
    }
bad:
    #if PY_MAJOR_VERSION < 3
    Py_XDECREF(py_import);
    #endif
    Py_XDECREF(empty_list);
    Py_XDECREF(empty_dict);
    return module;
}

/* ImportFrom */
  static PyObject* __Pyx_ImportFrom(PyObject* module, PyObject* name) {
    PyObject* value = __Pyx_PyObject_GetAttrStr(module, name);
    if (unlikely(!value) && PyErr_ExceptionMatches(PyExc_AttributeError)) {
        PyErr_Format(PyExc_ImportError,
        #if PY_MAJOR_VERSION < 3
            "cannot import name %.230s", PyString_AS_STRING(name));
        #else
            "cannot import name %S", name);
        #endif
    }
    return value;
}

/* HasAttr */
  static CYTHON_INLINE int __Pyx_HasAttr(PyObject *o, PyObject *n) {
    PyObject *r;
    if (unlikely(!__Pyx_PyBaseString_Check(n))) {
        PyErr_SetString(PyExc_TypeError,
                        "hasattr(): attribute name must be string");
        return -1;
    }
    r = __Pyx_GetAttr(o, n);
    if (unlikely(!r)) {
        PyErr_Clear();
        return 0;
    } else {
        Py_DECREF(r);
        return 1;
    }
}

/* GetTopmostException */
  #if CYTHON_USE_EXC_INFO_STACK
static _PyErr_StackItem *
__Pyx_PyErr_GetTopmostException(PyThreadState *tstate)
{
    _PyErr_StackItem *exc_info = tstate->exc_info;
    while ((exc_info->exc_type == NULL || exc_info->exc_type == Py_None) &&
           exc_info->previous_item != NULL)
    {
        exc_info = exc_info->previous_item;
    }
    return exc_info;
}
#endif

/* SaveResetException */
  #if CYTHON_FAST_THREAD_STATE
static CYTHON_INLINE void __Pyx__ExceptionSave(PyThreadState *tstate, PyObject **type, PyObject **value, PyObject **tb) {
    #if CYTHON_USE_EXC_INFO_STACK
    _PyErr_StackItem *exc_info = __Pyx_PyErr_GetTopmostException(tstate);
    *type = exc_info->exc_type;
    *value = exc_info->exc_value;
    *tb = exc_info->exc_traceback;
    #else
    *type = tstate->exc_type;
    *value = tstate->exc_value;
    *tb = tstate->exc_traceback;
    #endif
    Py_XINCREF(*type);
    Py_XINCREF(*value);
    Py_XINCREF(*tb);
}
static CYTHON_INLINE void __Pyx__ExceptionReset(PyThreadState *tstate, PyObject *type, PyObject *value, PyObject *tb) {
    PyObject *tmp_type, *tmp_value, *tmp_tb;
    #if CYTHON_USE_EXC_INFO_STACK
    _PyErr_StackItem *exc_info = tstate->exc_info;
    tmp_type = exc_info->exc_type;
    tmp_value = exc_info->exc_value;
    tmp_tb = exc_info->exc_traceback;
    exc_info->exc_type = type;
    exc_info->exc_value = value;
    exc_info->exc_traceback = tb;
    #else
    tmp_type = tstate->exc_type;
    tmp_value = tstate->exc_value;
    tmp_tb = tstate->exc_traceback;
    tstate->exc_type = type;
    tstate->exc_value = value;
    tstate->exc_traceback = tb;
    #endif
    Py_XDECREF(tmp_type);
    Py_XDECREF(tmp_value);
    Py_XDECREF(tmp_tb);
}
#endif

/* GetException */
  #if CYTHON_FAST_THREAD_STATE
static int __Pyx__GetException(PyThreadState *tstate, PyObject **type, PyObject **value, PyObject **tb)
#else
static int __Pyx_GetException(PyObject **type, PyObject **value, PyObject **tb)
#endif
{
    PyObject *local_type, *local_value, *local_tb;
#if CYTHON_FAST_THREAD_STATE
    PyObject *tmp_type, *tmp_value, *tmp_tb;
    local_type = tstate->curexc_type;
    local_value = tstate->curexc_value;
    local_tb = tstate->curexc_traceback;
    tstate->curexc_type = 0;
    tstate->curexc_value = 0;
    tstate->curexc_traceback = 0;
#else
    PyErr_Fetch(&local_type, &local_value, &local_tb);
#endif
    PyErr_NormalizeException(&local_type, &local_value, &local_tb);
#if CYTHON_FAST_THREAD_STATE
    if (unlikely(tstate->curexc_type))
#else
    if (unlikely(PyErr_Occurred()))
#endif
        goto bad;
    #if PY_MAJOR_VERSION >= 3
    if (local_tb) {
        if (unlikely(PyException_SetTraceback(local_value, local_tb) < 0))
            goto bad;
    }
    #endif
    Py_XINCREF(local_tb);
    Py_XINCREF(local_type);
    Py_XINCREF(local_value);
    *type = local_type;
    *value = local_value;
    *tb = local_tb;
#if CYTHON_FAST_THREAD_STATE
    #if CYTHON_USE_EXC_INFO_STACK
    {
        _PyErr_StackItem *exc_info = tstate->exc_info;
        tmp_type = exc_info->exc_type;
        tmp_value = exc_info->exc_value;
        tmp_tb = exc_info->exc_traceback;
        exc_info->exc_type = local_type;
        exc_info->exc_value = local_value;
        exc_info->exc_traceback = local_tb;
    }
    #else
    tmp_type = tstate->exc_type;
    tmp_value = tstate->exc_value;
    tmp_tb = tstate->exc_traceback;
    tstate->exc_type = local_type;
    tstate->exc_value = local_value;
    tstate->exc_traceback = local_tb;
    #endif
    Py_XDECREF(tmp_type);
    Py_XDECREF(tmp_value);
    Py_XDECREF(tmp_tb);
#else
    PyErr_SetExcInfo(local_type, local_value, local_tb);
#endif
    return 0;
bad:
    *type = 0;
    *value = 0;
    *tb = 0;
    Py_XDECREF(local_type);
    Py_XDECREF(local_value);
    Py_XDECREF(local_tb);
    return -1;
}

/* PyObjectSetAttrStr */
  #if CYTHON_USE_TYPE_SLOTS
static CYTHON_INLINE int __Pyx_PyObject_SetAttrStr(PyObject* obj, PyObject* attr_name, PyObject* value) {
    PyTypeObject* tp = Py_TYPE(obj);
    if (likely(tp->tp_setattro))
        return tp->tp_setattro(obj, attr_name, value);
#if PY_MAJOR_VERSION < 3
    if (likely(tp->tp_setattr))
        return tp->tp_setattr(obj, PyString_AS_STRING(attr_name), value);
#endif
    return PyObject_SetAttr(obj, attr_name, value);
}
#endif

/* ObjectGetItem */
  #if CYTHON_USE_TYPE_SLOTS
static PyObject *__Pyx_PyObject_GetIndex(PyObject *obj, PyObject* index) {
    PyObject *runerr;
    Py_ssize_t key_value;
    PySequenceMethods *m = Py_TYPE(obj)->tp_as_sequence;
    if (unlikely(!(m && m->sq_item))) {
        PyErr_Format(PyExc_TypeError, "'%.200s' object is not subscriptable", Py_TYPE(obj)->tp_name);
        return NULL;
    }
    key_value = __Pyx_PyIndex_AsSsize_t(index);
    if (likely(key_value != -1 || !(runerr = PyErr_Occurred()))) {
        return __Pyx_GetItemInt_Fast(obj, key_value, 0, 1, 1);
    }
    if (PyErr_GivenExceptionMatches(runerr, PyExc_OverflowError)) {
        PyErr_Clear();
        PyErr_Format(PyExc_IndexError, "cannot fit '%.200s' into an index-sized integer", Py_TYPE(index)->tp_name);
    }
    return NULL;
}
static PyObject *__Pyx_PyObject_GetItem(PyObject *obj, PyObject* key) {
    PyMappingMethods *m = Py_TYPE(obj)->tp_as_mapping;
    if (likely(m && m->mp_subscript)) {
        return m->mp_subscript(obj, key);
    }
    return __Pyx_PyObject_GetIndex(obj, key);
}
#endif

/* PyObject_GenericGetAttrNoDict */
  #if CYTHON_USE_TYPE_SLOTS && CYTHON_USE_PYTYPE_LOOKUP && PY_VERSION_HEX < 0x03070000
static PyObject *__Pyx_RaiseGenericGetAttributeError(PyTypeObject *tp, PyObject *attr_name) {
    PyErr_Format(PyExc_AttributeError,
#if PY_MAJOR_VERSION >= 3
                 "'%.50s' object has no attribute '%U'",
                 tp->tp_name, attr_name);
#else
                 "'%.50s' object has no attribute '%.400s'",
                 tp->tp_name, PyString_AS_STRING(attr_name));
#endif
    return NULL;
}
static CYTHON_INLINE PyObject* __Pyx_PyObject_GenericGetAttrNoDict(PyObject* obj, PyObject* attr_name) {
    PyObject *descr;
    PyTypeObject *tp = Py_TYPE(obj);
    if (unlikely(!PyString_Check(attr_name))) {
        return PyObject_GenericGetAttr(obj, attr_name);
    }
    assert(!tp->tp_dictoffset);
    descr = _PyType_Lookup(tp, attr_name);
    if (unlikely(!descr)) {
        return __Pyx_RaiseGenericGetAttributeError(tp, attr_name);
    }
    Py_INCREF(descr);
    #if PY_MAJOR_VERSION < 3
    if (likely(PyType_HasFeature(Py_TYPE(descr), Py_TPFLAGS_HAVE_CLASS)))
    #endif
    {
        descrgetfunc f = Py_TYPE(descr)->tp_descr_get;
        if (unlikely(f)) {
            PyObject *res = f(descr, obj, (PyObject *)tp);
            Py_DECREF(descr);
            return res;
        }
    }
    return descr;
}
#endif

/* SetVTable */
  static int __Pyx_SetVtable(PyObject *dict, void *vtable) {
#if PY_VERSION_HEX >= 0x02070000
    PyObject *ob = PyCapsule_New(vtable, 0, 0);
#else
    PyObject *ob = PyCObject_FromVoidPtr(vtable, 0);
#endif
    if (!ob)
        goto bad;
    if (PyDict_SetItem(dict, __pyx_n_s_pyx_vtable, ob) < 0)
        goto bad;
    Py_DECREF(ob);
    return 0;
bad:
    Py_XDECREF(ob);
    return -1;
}

/* SetupReduce */
  static int __Pyx_setup_reduce_is_named(PyObject* meth, PyObject* name) {
  int ret;
  PyObject *name_attr;
  name_attr = __Pyx_PyObject_GetAttrStr(meth, __pyx_n_s_name_2);
  if (likely(name_attr)) {
      ret = PyObject_RichCompareBool(name_attr, name, Py_EQ);
  } else {
      ret = -1;
  }
  if (unlikely(ret < 0)) {
      PyErr_Clear();
      ret = 0;
  }
  Py_XDECREF(name_attr);
  return ret;
}
static int __Pyx_setup_reduce(PyObject* type_obj) {
    int ret = 0;
    PyObject *object_reduce = NULL;
    PyObject *object_reduce_ex = NULL;
    PyObject *reduce = NULL;
    PyObject *reduce_ex = NULL;
    PyObject *reduce_cython = NULL;
    PyObject *setstate = NULL;
    PyObject *setstate_cython = NULL;
#if CYTHON_USE_PYTYPE_LOOKUP
    if (_PyType_Lookup((PyTypeObject*)type_obj, __pyx_n_s_getstate)) goto __PYX_GOOD;
#else
    if (PyObject_HasAttr(type_obj, __pyx_n_s_getstate)) goto __PYX_GOOD;
#endif
#if CYTHON_USE_PYTYPE_LOOKUP
    object_reduce_ex = _PyType_Lookup(&PyBaseObject_Type, __pyx_n_s_reduce_ex); if (!object_reduce_ex) goto __PYX_BAD;
#else
    object_reduce_ex = __Pyx_PyObject_GetAttrStr((PyObject*)&PyBaseObject_Type, __pyx_n_s_reduce_ex); if (!object_reduce_ex) goto __PYX_BAD;
#endif
    reduce_ex = __Pyx_PyObject_GetAttrStr(type_obj, __pyx_n_s_reduce_ex); if (unlikely(!reduce_ex)) goto __PYX_BAD;
    if (reduce_ex == object_reduce_ex) {
#if CYTHON_USE_PYTYPE_LOOKUP
        object_reduce = _PyType_Lookup(&PyBaseObject_Type, __pyx_n_s_reduce); if (!object_reduce) goto __PYX_BAD;
#else
        object_reduce = __Pyx_PyObject_GetAttrStr((PyObject*)&PyBaseObject_Type, __pyx_n_s_reduce); if (!object_reduce) goto __PYX_BAD;
#endif
        reduce = __Pyx_PyObject_GetAttrStr(type_obj, __pyx_n_s_reduce); if (unlikely(!reduce)) goto __PYX_BAD;
        if (reduce == object_reduce || __Pyx_setup_reduce_is_named(reduce, __pyx_n_s_reduce_cython)) {
            reduce_cython = __Pyx_PyObject_GetAttrStr(type_obj, __pyx_n_s_reduce_cython); if (unlikely(!reduce_cython)) goto __PYX_BAD;
            ret = PyDict_SetItem(((PyTypeObject*)type_obj)->tp_dict, __pyx_n_s_reduce, reduce_cython); if (unlikely(ret < 0)) goto __PYX_BAD;
            ret = PyDict_DelItem(((PyTypeObject*)type_obj)->tp_dict, __pyx_n_s_reduce_cython); if (unlikely(ret < 0)) goto __PYX_BAD;
            setstate = __Pyx_PyObject_GetAttrStr(type_obj, __pyx_n_s_setstate);
            if (!setstate) PyErr_Clear();
            if (!setstate || __Pyx_setup_reduce_is_named(setstate, __pyx_n_s_setstate_cython)) {
                setstate_cython = __Pyx_PyObject_GetAttrStr(type_obj, __pyx_n_s_setstate_cython); if (unlikely(!setstate_cython)) goto __PYX_BAD;
                ret = PyDict_SetItem(((PyTypeObject*)type_obj)->tp_dict, __pyx_n_s_setstate, setstate_cython); if (unlikely(ret < 0)) goto __PYX_BAD;
                ret = PyDict_DelItem(((PyTypeObject*)type_obj)->tp_dict, __pyx_n_s_setstate_cython); if (unlikely(ret < 0)) goto __PYX_BAD;
            }
            PyType_Modified((PyTypeObject*)type_obj);
        }
    }
    goto __PYX_GOOD;
__PYX_BAD:
    if (!PyErr_Occurred())
        PyErr_Format(PyExc_RuntimeError, "Unable to initialize pickling for %s", ((PyTypeObject*)type_obj)->tp_name);
    ret = -1;
__PYX_GOOD:
#if !CYTHON_USE_PYTYPE_LOOKUP
    Py_XDECREF(object_reduce);
    Py_XDECREF(object_reduce_ex);
#endif
    Py_XDECREF(reduce);
    Py_XDECREF(reduce_ex);
    Py_XDECREF(reduce_cython);
    Py_XDECREF(setstate);
    Py_XDECREF(setstate_cython);
    return ret;
}

/* PyObject_GenericGetAttr */
  #if CYTHON_USE_TYPE_SLOTS && CYTHON_USE_PYTYPE_LOOKUP && PY_VERSION_HEX < 0x03070000
static PyObject* __Pyx_PyObject_GenericGetAttr(PyObject* obj, PyObject* attr_name) {
    if (unlikely(Py_TYPE(obj)->tp_dictoffset)) {
        return PyObject_GenericGetAttr(obj, attr_name);
    }
    return __Pyx_PyObject_GenericGetAttrNoDict(obj, attr_name);
}
#endif

/* TypeImport */
  #ifndef __PYX_HAVE_RT_ImportType
#define __PYX_HAVE_RT_ImportType
static PyTypeObject *__Pyx_ImportType(PyObject *module, const char *module_name, const char *class_name,
    size_t size, enum __Pyx_ImportType_CheckSize check_size)
{
    PyObject *result = 0;
    char warning[200];
    Py_ssize_t basicsize;
#ifdef Py_LIMITED_API
    PyObject *py_basicsize;
#endif
    result = PyObject_GetAttrString(module, class_name);
    if (!result)
        goto bad;
    if (!PyType_Check(result)) {
        PyErr_Format(PyExc_TypeError,
            "%.200s.%.200s is not a type object",
            module_name, class_name);
        goto bad;
    }
#ifndef Py_LIMITED_API
    basicsize = ((PyTypeObject *)result)->tp_basicsize;
#else
    py_basicsize = PyObject_GetAttrString(result, "__basicsize__");
    if (!py_basicsize)
        goto bad;
    basicsize = PyLong_AsSsize_t(py_basicsize);
    Py_DECREF(py_basicsize);
    py_basicsize = 0;
    if (basicsize == (Py_ssize_t)-1 && PyErr_Occurred())
        goto bad;
#endif
    if ((size_t)basicsize < size) {
        PyErr_Format(PyExc_ValueError,
            "%.200s.%.200s size changed, may indicate binary incompatibility. "
            "Expected %zd from C header, got %zd from PyObject",
            module_name, class_name, size, basicsize);
        goto bad;
    }
    if (check_size == __Pyx_ImportType_CheckSize_Error && (size_t)basicsize != size) {
        PyErr_Format(PyExc_ValueError,
            "%.200s.%.200s size changed, may indicate binary incompatibility. "
            "Expected %zd from C header, got %zd from PyObject",
            module_name, class_name, size, basicsize);
        goto bad;
    }
    else if (check_size == __Pyx_ImportType_CheckSize_Warn && (size_t)basicsize > size) {
        PyOS_snprintf(warning, sizeof(warning),
            "%s.%s size changed, may indicate binary incompatibility. "
            "Expected %zd from C header, got %zd from PyObject",
            module_name, class_name, size, basicsize);
        if (PyErr_WarnEx(NULL, warning, 0) < 0) goto bad;
    }
    return (PyTypeObject *)result;
bad:
    Py_XDECREF(result);
    return NULL;
}
#endif

/* GetVTable */
  static void* __Pyx_GetVtable(PyObject *dict) {
    void* ptr;
    PyObject *ob = PyObject_GetItem(dict, __pyx_n_s_pyx_vtable);
    if (!ob)
        goto bad;
#if PY_VERSION_HEX >= 0x02070000
    ptr = PyCapsule_GetPointer(ob, 0);
#else
    ptr = PyCObject_AsVoidPtr(ob);
#endif
    if (!ptr && !PyErr_Occurred())
        PyErr_SetString(PyExc_RuntimeError, "invalid vtable found for imported type");
    Py_DECREF(ob);
    return ptr;
bad:
    Py_XDECREF(ob);
    return NULL;
}

/* FetchCommonType */
  static PyTypeObject* __Pyx_FetchCommonType(PyTypeObject* type) {
    PyObject* fake_module;
    PyTypeObject* cached_type = NULL;
    fake_module = PyImport_AddModule((char*) "_cython_" CYTHON_ABI);
    if (!fake_module) return NULL;
    Py_INCREF(fake_module);
    cached_type = (PyTypeObject*) PyObject_GetAttrString(fake_module, type->tp_name);
    if (cached_type) {
        if (!PyType_Check((PyObject*)cached_type)) {
            PyErr_Format(PyExc_TypeError,
                "Shared Cython type %.200s is not a type object",
                type->tp_name);
            goto bad;
        }
        if (cached_type->tp_basicsize != type->tp_basicsize) {
            PyErr_Format(PyExc_TypeError,
                "Shared Cython type %.200s has the wrong size, try recompiling",
                type->tp_name);
            goto bad;
        }
    } else {
        if (!PyErr_ExceptionMatches(PyExc_AttributeError)) goto bad;
        PyErr_Clear();
        if (PyType_Ready(type) < 0) goto bad;
        if (PyObject_SetAttrString(fake_module, type->tp_name, (PyObject*) type) < 0)
            goto bad;
        Py_INCREF(type);
        cached_type = type;
    }
done:
    Py_DECREF(fake_module);
    return cached_type;
bad:
    Py_XDECREF(cached_type);
    cached_type = NULL;
    goto done;
}

/* CythonFunction */
  #include <structmember.h>
static PyObject *
__Pyx_CyFunction_get_doc(__pyx_CyFunctionObject *op, CYTHON_UNUSED void *closure)
{
    if (unlikely(op->func_doc == NULL)) {
        if (op->func.m_ml->ml_doc) {
#if PY_MAJOR_VERSION >= 3
            op->func_doc = PyUnicode_FromString(op->func.m_ml->ml_doc);
#else
            op->func_doc = PyString_FromString(op->func.m_ml->ml_doc);
#endif
            if (unlikely(op->func_doc == NULL))
                return NULL;
        } else {
            Py_INCREF(Py_None);
            return Py_None;
        }
    }
    Py_INCREF(op->func_doc);
    return op->func_doc;
}
static int
__Pyx_CyFunction_set_doc(__pyx_CyFunctionObject *op, PyObject *value, CYTHON_UNUSED void *context)
{
    PyObject *tmp = op->func_doc;
    if (value == NULL) {
        value = Py_None;
    }
    Py_INCREF(value);
    op->func_doc = value;
    Py_XDECREF(tmp);
    return 0;
}
static PyObject *
__Pyx_CyFunction_get_name(__pyx_CyFunctionObject *op, CYTHON_UNUSED void *context)
{
    if (unlikely(op->func_name == NULL)) {
#if PY_MAJOR_VERSION >= 3
        op->func_name = PyUnicode_InternFromString(op->func.m_ml->ml_name);
#else
        op->func_name = PyString_InternFromString(op->func.m_ml->ml_name);
#endif
        if (unlikely(op->func_name == NULL))
            return NULL;
    }
    Py_INCREF(op->func_name);
    return op->func_name;
}
static int
__Pyx_CyFunction_set_name(__pyx_CyFunctionObject *op, PyObject *value, CYTHON_UNUSED void *context)
{
    PyObject *tmp;
#if PY_MAJOR_VERSION >= 3
    if (unlikely(value == NULL || !PyUnicode_Check(value)))
#else
    if (unlikely(value == NULL || !PyString_Check(value)))
#endif
    {
        PyErr_SetString(PyExc_TypeError,
                        "__name__ must be set to a string object");
        return -1;
    }
    tmp = op->func_name;
    Py_INCREF(value);
    op->func_name = value;
    Py_XDECREF(tmp);
    return 0;
}
static PyObject *
__Pyx_CyFunction_get_qualname(__pyx_CyFunctionObject *op, CYTHON_UNUSED void *context)
{
    Py_INCREF(op->func_qualname);
    return op->func_qualname;
}
static int
__Pyx_CyFunction_set_qualname(__pyx_CyFunctionObject *op, PyObject *value, CYTHON_UNUSED void *context)
{
    PyObject *tmp;
#if PY_MAJOR_VERSION >= 3
    if (unlikely(value == NULL || !PyUnicode_Check(value)))
#else
    if (unlikely(value == NULL || !PyString_Check(value)))
#endif
    {
        PyErr_SetString(PyExc_TypeError,
                        "__qualname__ must be set to a string object");
        return -1;
    }
    tmp = op->func_qualname;
    Py_INCREF(value);
    op->func_qualname = value;
    Py_XDECREF(tmp);
    return 0;
}
static PyObject *
__Pyx_CyFunction_get_self(__pyx_CyFunctionObject *m, CYTHON_UNUSED void *closure)
{
    PyObject *self;
    self = m->func_closure;
    if (self == NULL)
        self = Py_None;
    Py_INCREF(self);
    return self;
}
static PyObject *
__Pyx_CyFunction_get_dict(__pyx_CyFunctionObject *op, CYTHON_UNUSED void *context)
{
    if (unlikely(op->func_dict == NULL)) {
        op->func_dict = PyDict_New();
        if (unlikely(op->func_dict == NULL))
            return NULL;
    }
    Py_INCREF(op->func_dict);
    return op->func_dict;
}
static int
__Pyx_CyFunction_set_dict(__pyx_CyFunctionObject *op, PyObject *value, CYTHON_UNUSED void *context)
{
    PyObject *tmp;
    if (unlikely(value == NULL)) {
        PyErr_SetString(PyExc_TypeError,
               "function's dictionary may not be deleted");
        return -1;
    }
    if (unlikely(!PyDict_Check(value))) {
        PyErr_SetString(PyExc_TypeError,
               "setting function's dictionary to a non-dict");
        return -1;
    }
    tmp = op->func_dict;
    Py_INCREF(value);
    op->func_dict = value;
    Py_XDECREF(tmp);
    return 0;
}
static PyObject *
__Pyx_CyFunction_get_globals(__pyx_CyFunctionObject *op, CYTHON_UNUSED void *context)
{
    Py_INCREF(op->func_globals);
    return op->func_globals;
}
static PyObject *
__Pyx_CyFunction_get_closure(CYTHON_UNUSED __pyx_CyFunctionObject *op, CYTHON_UNUSED void *context)
{
    Py_INCREF(Py_None);
    return Py_None;
}
static PyObject *
__Pyx_CyFunction_get_code(__pyx_CyFunctionObject *op, CYTHON_UNUSED void *context)
{
    PyObject* result = (op->func_code) ? op->func_code : Py_None;
    Py_INCREF(result);
    return result;
}
static int
__Pyx_CyFunction_init_defaults(__pyx_CyFunctionObject *op) {
    int result = 0;
    PyObject *res = op->defaults_getter((PyObject *) op);
    if (unlikely(!res))
        return -1;
    #if CYTHON_ASSUME_SAFE_MACROS && !CYTHON_AVOID_BORROWED_REFS
    op->defaults_tuple = PyTuple_GET_ITEM(res, 0);
    Py_INCREF(op->defaults_tuple);
    op->defaults_kwdict = PyTuple_GET_ITEM(res, 1);
    Py_INCREF(op->defaults_kwdict);
    #else
    op->defaults_tuple = PySequence_ITEM(res, 0);
    if (unlikely(!op->defaults_tuple)) result = -1;
    else {
        op->defaults_kwdict = PySequence_ITEM(res, 1);
        if (unlikely(!op->defaults_kwdict)) result = -1;
    }
    #endif
    Py_DECREF(res);
    return result;
}
static int
__Pyx_CyFunction_set_defaults(__pyx_CyFunctionObject *op, PyObject* value, CYTHON_UNUSED void *context) {
    PyObject* tmp;
    if (!value) {
        value = Py_None;
    } else if (value != Py_None && !PyTuple_Check(value)) {
        PyErr_SetString(PyExc_TypeError,
                        "__defaults__ must be set to a tuple object");
        return -1;
    }
    Py_INCREF(value);
    tmp = op->defaults_tuple;
    op->defaults_tuple = value;
    Py_XDECREF(tmp);
    return 0;
}
static PyObject *
__Pyx_CyFunction_get_defaults(__pyx_CyFunctionObject *op, CYTHON_UNUSED void *context) {
    PyObject* result = op->defaults_tuple;
    if (unlikely(!result)) {
        if (op->defaults_getter) {
            if (__Pyx_CyFunction_init_defaults(op) < 0) return NULL;
            result = op->defaults_tuple;
        } else {
            result = Py_None;
        }
    }
    Py_INCREF(result);
    return result;
}
static int
__Pyx_CyFunction_set_kwdefaults(__pyx_CyFunctionObject *op, PyObject* value, CYTHON_UNUSED void *context) {
    PyObject* tmp;
    if (!value) {
        value = Py_None;
    } else if (value != Py_None && !PyDict_Check(value)) {
        PyErr_SetString(PyExc_TypeError,
                        "__kwdefaults__ must be set to a dict object");
        return -1;
    }
    Py_INCREF(value);
    tmp = op->defaults_kwdict;
    op->defaults_kwdict = value;
    Py_XDECREF(tmp);
    return 0;
}
static PyObject *
__Pyx_CyFunction_get_kwdefaults(__pyx_CyFunctionObject *op, CYTHON_UNUSED void *context) {
    PyObject* result = op->defaults_kwdict;
    if (unlikely(!result)) {
        if (op->defaults_getter) {
            if (__Pyx_CyFunction_init_defaults(op) < 0) return NULL;
            result = op->defaults_kwdict;
        } else {
            result = Py_None;
        }
    }
    Py_INCREF(result);
    return result;
}
static int
__Pyx_CyFunction_set_annotations(__pyx_CyFunctionObject *op, PyObject* value, CYTHON_UNUSED void *context) {
    PyObject* tmp;
    if (!value || value == Py_None) {
        value = NULL;
    } else if (!PyDict_Check(value)) {
        PyErr_SetString(PyExc_TypeError,
                        "__annotations__ must be set to a dict object");
        return -1;
    }
    Py_XINCREF(value);
    tmp = op->func_annotations;
    op->func_annotations = value;
    Py_XDECREF(tmp);
    return 0;
}
static PyObject *
__Pyx_CyFunction_get_annotations(__pyx_CyFunctionObject *op, CYTHON_UNUSED void *context) {
    PyObject* result = op->func_annotations;
    if (unlikely(!result)) {
        result = PyDict_New();
        if (unlikely(!result)) return NULL;
        op->func_annotations = result;
    }
    Py_INCREF(result);
    return result;
}
static PyGetSetDef __pyx_CyFunction_getsets[] = {
    {(char *) "func_doc", (getter)__Pyx_CyFunction_get_doc, (setter)__Pyx_CyFunction_set_doc, 0, 0},
    {(char *) "__doc__",  (getter)__Pyx_CyFunction_get_doc, (setter)__Pyx_CyFunction_set_doc, 0, 0},
    {(char *) "func_name", (getter)__Pyx_CyFunction_get_name, (setter)__Pyx_CyFunction_set_name, 0, 0},
    {(char *) "__name__", (getter)__Pyx_CyFunction_get_name, (setter)__Pyx_CyFunction_set_name, 0, 0},
    {(char *) "__qualname__", (getter)__Pyx_CyFunction_get_qualname, (setter)__Pyx_CyFunction_set_qualname, 0, 0},
    {(char *) "__self__", (getter)__Pyx_CyFunction_get_self, 0, 0, 0},
    {(char *) "func_dict", (getter)__Pyx_CyFunction_get_dict, (setter)__Pyx_CyFunction_set_dict, 0, 0},
    {(char *) "__dict__", (getter)__Pyx_CyFunction_get_dict, (setter)__Pyx_CyFunction_set_dict, 0, 0},
    {(char *) "func_globals", (getter)__Pyx_CyFunction_get_globals, 0, 0, 0},
    {(char *) "__globals__", (getter)__Pyx_CyFunction_get_globals, 0, 0, 0},
    {(char *) "func_closure", (getter)__Pyx_CyFunction_get_closure, 0, 0, 0},
    {(char *) "__closure__", (getter)__Pyx_CyFunction_get_closure, 0, 0, 0},
    {(char *) "func_code", (getter)__Pyx_CyFunction_get_code, 0, 0, 0},
    {(char *) "__code__", (getter)__Pyx_CyFunction_get_code, 0, 0, 0},
    {(char *) "func_defaults", (getter)__Pyx_CyFunction_get_defaults, (setter)__Pyx_CyFunction_set_defaults, 0, 0},
    {(char *) "__defaults__", (getter)__Pyx_CyFunction_get_defaults, (setter)__Pyx_CyFunction_set_defaults, 0, 0},
    {(char *) "__kwdefaults__", (getter)__Pyx_CyFunction_get_kwdefaults, (setter)__Pyx_CyFunction_set_kwdefaults, 0, 0},
    {(char *) "__annotations__", (getter)__Pyx_CyFunction_get_annotations, (setter)__Pyx_CyFunction_set_annotations, 0, 0},
    {0, 0, 0, 0, 0}
};
static PyMemberDef __pyx_CyFunction_members[] = {
    {(char *) "__module__", T_OBJECT, offsetof(PyCFunctionObject, m_module), PY_WRITE_RESTRICTED, 0},
    {0, 0, 0,  0, 0}
};
static PyObject *
__Pyx_CyFunction_reduce(__pyx_CyFunctionObject *m, CYTHON_UNUSED PyObject *args)
{
#if PY_MAJOR_VERSION >= 3
    return PyUnicode_FromString(m->func.m_ml->ml_name);
#else
    return PyString_FromString(m->func.m_ml->ml_name);
#endif
}
static PyMethodDef __pyx_CyFunction_methods[] = {
    {"__reduce__", (PyCFunction)__Pyx_CyFunction_reduce, METH_VARARGS, 0},
    {0, 0, 0, 0}
};
#if PY_VERSION_HEX < 0x030500A0
#define __Pyx_CyFunction_weakreflist(cyfunc) ((cyfunc)->func_weakreflist)
#else
#define __Pyx_CyFunction_weakreflist(cyfunc) ((cyfunc)->func.m_weakreflist)
#endif
static PyObject *__Pyx_CyFunction_New(PyTypeObject *type, PyMethodDef *ml, int flags, PyObject* qualname,
                                      PyObject *closure, PyObject *module, PyObject* globals, PyObject* code) {
    __pyx_CyFunctionObject *op = PyObject_GC_New(__pyx_CyFunctionObject, type);
    if (op == NULL)
        return NULL;
    op->flags = flags;
    __Pyx_CyFunction_weakreflist(op) = NULL;
    op->func.m_ml = ml;
    op->func.m_self = (PyObject *) op;
    Py_XINCREF(closure);
    op->func_closure = closure;
    Py_XINCREF(module);
    op->func.m_module = module;
    op->func_dict = NULL;
    op->func_name = NULL;
    Py_INCREF(qualname);
    op->func_qualname = qualname;
    op->func_doc = NULL;
    op->func_classobj = NULL;
    op->func_globals = globals;
    Py_INCREF(op->func_globals);
    Py_XINCREF(code);
    op->func_code = code;
    op->defaults_pyobjects = 0;
    op->defaults = NULL;
    op->defaults_tuple = NULL;
    op->defaults_kwdict = NULL;
    op->defaults_getter = NULL;
    op->func_annotations = NULL;
    PyObject_GC_Track(op);
    return (PyObject *) op;
}
static int
__Pyx_CyFunction_clear(__pyx_CyFunctionObject *m)
{
    Py_CLEAR(m->func_closure);
    Py_CLEAR(m->func.m_module);
    Py_CLEAR(m->func_dict);
    Py_CLEAR(m->func_name);
    Py_CLEAR(m->func_qualname);
    Py_CLEAR(m->func_doc);
    Py_CLEAR(m->func_globals);
    Py_CLEAR(m->func_code);
    Py_CLEAR(m->func_classobj);
    Py_CLEAR(m->defaults_tuple);
    Py_CLEAR(m->defaults_kwdict);
    Py_CLEAR(m->func_annotations);
    if (m->defaults) {
        PyObject **pydefaults = __Pyx_CyFunction_Defaults(PyObject *, m);
        int i;
        for (i = 0; i < m->defaults_pyobjects; i++)
            Py_XDECREF(pydefaults[i]);
        PyObject_Free(m->defaults);
        m->defaults = NULL;
    }
    return 0;
}
static void __Pyx__CyFunction_dealloc(__pyx_CyFunctionObject *m)
{
    if (__Pyx_CyFunction_weakreflist(m) != NULL)
        PyObject_ClearWeakRefs((PyObject *) m);
    __Pyx_CyFunction_clear(m);
    PyObject_GC_Del(m);
}
static void __Pyx_CyFunction_dealloc(__pyx_CyFunctionObject *m)
{
    PyObject_GC_UnTrack(m);
    __Pyx__CyFunction_dealloc(m);
}
static int __Pyx_CyFunction_traverse(__pyx_CyFunctionObject *m, visitproc visit, void *arg)
{
    Py_VISIT(m->func_closure);
    Py_VISIT(m->func.m_module);
    Py_VISIT(m->func_dict);
    Py_VISIT(m->func_name);
    Py_VISIT(m->func_qualname);
    Py_VISIT(m->func_doc);
    Py_VISIT(m->func_globals);
    Py_VISIT(m->func_code);
    Py_VISIT(m->func_classobj);
    Py_VISIT(m->defaults_tuple);
    Py_VISIT(m->defaults_kwdict);
    if (m->defaults) {
        PyObject **pydefaults = __Pyx_CyFunction_Defaults(PyObject *, m);
        int i;
        for (i = 0; i < m->defaults_pyobjects; i++)
            Py_VISIT(pydefaults[i]);
    }
    return 0;
}
static PyObject *__Pyx_CyFunction_descr_get(PyObject *func, PyObject *obj, PyObject *type)
{
    __pyx_CyFunctionObject *m = (__pyx_CyFunctionObject *) func;
    if (m->flags & __Pyx_CYFUNCTION_STATICMETHOD) {
        Py_INCREF(func);
        return func;
    }
    if (m->flags & __Pyx_CYFUNCTION_CLASSMETHOD) {
        if (type == NULL)
            type = (PyObject *)(Py_TYPE(obj));
        return __Pyx_PyMethod_New(func, type, (PyObject *)(Py_TYPE(type)));
    }
    if (obj == Py_None)
        obj = NULL;
    return __Pyx_PyMethod_New(func, obj, type);
}
static PyObject*
__Pyx_CyFunction_repr(__pyx_CyFunctionObject *op)
{
#if PY_MAJOR_VERSION >= 3
    return PyUnicode_FromFormat("<cyfunction %U at %p>",
                                op->func_qualname, (void *)op);
#else
    return PyString_FromFormat("<cyfunction %s at %p>",
                               PyString_AsString(op->func_qualname), (void *)op);
#endif
}
static PyObject * __Pyx_CyFunction_CallMethod(PyObject *func, PyObject *self, PyObject *arg, PyObject *kw) {
    PyCFunctionObject* f = (PyCFunctionObject*)func;
    PyCFunction meth = f->m_ml->ml_meth;
    Py_ssize_t size;
    switch (f->m_ml->ml_flags & (METH_VARARGS | METH_KEYWORDS | METH_NOARGS | METH_O)) {
    case METH_VARARGS:
        if (likely(kw == NULL || PyDict_Size(kw) == 0))
            return (*meth)(self, arg);
        break;
    case METH_VARARGS | METH_KEYWORDS:
        return (*(PyCFunctionWithKeywords)(void*)meth)(self, arg, kw);
    case METH_NOARGS:
        if (likely(kw == NULL || PyDict_Size(kw) == 0)) {
            size = PyTuple_GET_SIZE(arg);
            if (likely(size == 0))
                return (*meth)(self, NULL);
            PyErr_Format(PyExc_TypeError,
                "%.200s() takes no arguments (%" CYTHON_FORMAT_SSIZE_T "d given)",
                f->m_ml->ml_name, size);
            return NULL;
        }
        break;
    case METH_O:
        if (likely(kw == NULL || PyDict_Size(kw) == 0)) {
            size = PyTuple_GET_SIZE(arg);
            if (likely(size == 1)) {
                PyObject *result, *arg0;
                #if CYTHON_ASSUME_SAFE_MACROS && !CYTHON_AVOID_BORROWED_REFS
                arg0 = PyTuple_GET_ITEM(arg, 0);
                #else
                arg0 = PySequence_ITEM(arg, 0); if (unlikely(!arg0)) return NULL;
                #endif
                result = (*meth)(self, arg0);
                #if !(CYTHON_ASSUME_SAFE_MACROS && !CYTHON_AVOID_BORROWED_REFS)
                Py_DECREF(arg0);
                #endif
                return result;
            }
            PyErr_Format(PyExc_TypeError,
                "%.200s() takes exactly one argument (%" CYTHON_FORMAT_SSIZE_T "d given)",
                f->m_ml->ml_name, size);
            return NULL;
        }
        break;
    default:
        PyErr_SetString(PyExc_SystemError, "Bad call flags in "
                        "__Pyx_CyFunction_Call. METH_OLDARGS is no "
                        "longer supported!");
        return NULL;
    }
    PyErr_Format(PyExc_TypeError, "%.200s() takes no keyword arguments",
                 f->m_ml->ml_name);
    return NULL;
}
static CYTHON_INLINE PyObject *__Pyx_CyFunction_Call(PyObject *func, PyObject *arg, PyObject *kw) {
    return __Pyx_CyFunction_CallMethod(func, ((PyCFunctionObject*)func)->m_self, arg, kw);
}
static PyObject *__Pyx_CyFunction_CallAsMethod(PyObject *func, PyObject *args, PyObject *kw) {
    PyObject *result;
    __pyx_CyFunctionObject *cyfunc = (__pyx_CyFunctionObject *) func;
    if ((cyfunc->flags & __Pyx_CYFUNCTION_CCLASS) && !(cyfunc->flags & __Pyx_CYFUNCTION_STATICMETHOD)) {
        Py_ssize_t argc;
        PyObject *new_args;
        PyObject *self;
        argc = PyTuple_GET_SIZE(args);
        new_args = PyTuple_GetSlice(args, 1, argc);
        if (unlikely(!new_args))
            return NULL;
        self = PyTuple_GetItem(args, 0);
        if (unlikely(!self)) {
            Py_DECREF(new_args);
            return NULL;
        }
        result = __Pyx_CyFunction_CallMethod(func, self, new_args, kw);
        Py_DECREF(new_args);
    } else {
        result = __Pyx_CyFunction_Call(func, args, kw);
    }
    return result;
}
static PyTypeObject __pyx_CyFunctionType_type = {
    PyVarObject_HEAD_INIT(0, 0)
    "cython_function_or_method",
    sizeof(__pyx_CyFunctionObject),
    0,
    (destructor) __Pyx_CyFunction_dealloc,
    0,
    0,
    0,
#if PY_MAJOR_VERSION < 3
    0,
#else
    0,
#endif
    (reprfunc) __Pyx_CyFunction_repr,
    0,
    0,
    0,
    0,
    __Pyx_CyFunction_CallAsMethod,
    0,
    0,
    0,
    0,
    Py_TPFLAGS_DEFAULT | Py_TPFLAGS_HAVE_GC,
    0,
    (traverseproc) __Pyx_CyFunction_traverse,
    (inquiry) __Pyx_CyFunction_clear,
    0,
#if PY_VERSION_HEX < 0x030500A0
    offsetof(__pyx_CyFunctionObject, func_weakreflist),
#else
    offsetof(PyCFunctionObject, m_weakreflist),
#endif
    0,
    0,
    __pyx_CyFunction_methods,
    __pyx_CyFunction_members,
    __pyx_CyFunction_getsets,
    0,
    0,
    __Pyx_CyFunction_descr_get,
    0,
    offsetof(__pyx_CyFunctionObject, func_dict),
    0,
    0,
    0,
    0,
    0,
    0,
    0,
    0,
    0,
    0,
    0,
    0,
#if PY_VERSION_HEX >= 0x030400a1
    0,
#endif
#if PY_VERSION_HEX >= 0x030800b1
    0,
#endif
#if PY_VERSION_HEX >= 0x030800b4 && PY_VERSION_HEX < 0x03090000
    0,
#endif
};
static int __pyx_CyFunction_init(void) {
    __pyx_CyFunctionType = __Pyx_FetchCommonType(&__pyx_CyFunctionType_type);
    if (unlikely(__pyx_CyFunctionType == NULL)) {
        return -1;
    }
    return 0;
}
static CYTHON_INLINE void *__Pyx_CyFunction_InitDefaults(PyObject *func, size_t size, int pyobjects) {
    __pyx_CyFunctionObject *m = (__pyx_CyFunctionObject *) func;
    m->defaults = PyObject_Malloc(size);
    if (unlikely(!m->defaults))
        return PyErr_NoMemory();
    memset(m->defaults, 0, size);
    m->defaults_pyobjects = pyobjects;
    return m->defaults;
}
static CYTHON_INLINE void __Pyx_CyFunction_SetDefaultsTuple(PyObject *func, PyObject *tuple) {
    __pyx_CyFunctionObject *m = (__pyx_CyFunctionObject *) func;
    m->defaults_tuple = tuple;
    Py_INCREF(tuple);
}
static CYTHON_INLINE void __Pyx_CyFunction_SetDefaultsKwDict(PyObject *func, PyObject *dict) {
    __pyx_CyFunctionObject *m = (__pyx_CyFunctionObject *) func;
    m->defaults_kwdict = dict;
    Py_INCREF(dict);
}
static CYTHON_INLINE void __Pyx_CyFunction_SetAnnotationsDict(PyObject *func, PyObject *dict) {
    __pyx_CyFunctionObject *m = (__pyx_CyFunctionObject *) func;
    m->func_annotations = dict;
    Py_INCREF(dict);
}

/* FusedFunction */
  static PyObject *
__pyx_FusedFunction_New(PyTypeObject *type, PyMethodDef *ml, int flags,
                        PyObject *qualname, PyObject *self,
                        PyObject *module, PyObject *globals,
                        PyObject *code)
{
    __pyx_FusedFunctionObject *fusedfunc =
        (__pyx_FusedFunctionObject *) __Pyx_CyFunction_New(type, ml, flags, qualname,
                                                           self, module, globals, code);
    if (!fusedfunc)
        return NULL;
    fusedfunc->__signatures__ = NULL;
    fusedfunc->type = NULL;
    fusedfunc->self = NULL;
    return (PyObject *) fusedfunc;
}
static void
__pyx_FusedFunction_dealloc(__pyx_FusedFunctionObject *self)
{
    PyObject_GC_UnTrack(self);
    Py_CLEAR(self->self);
    Py_CLEAR(self->type);
    Py_CLEAR(self->__signatures__);
    __Pyx__CyFunction_dealloc((__pyx_CyFunctionObject *) self);
}
static int
__pyx_FusedFunction_traverse(__pyx_FusedFunctionObject *self,
                             visitproc visit,
                             void *arg)
{
    Py_VISIT(self->self);
    Py_VISIT(self->type);
    Py_VISIT(self->__signatures__);
    return __Pyx_CyFunction_traverse((__pyx_CyFunctionObject *) self, visit, arg);
}
static int
__pyx_FusedFunction_clear(__pyx_FusedFunctionObject *self)
{
    Py_CLEAR(self->self);
    Py_CLEAR(self->type);
    Py_CLEAR(self->__signatures__);
    return __Pyx_CyFunction_clear((__pyx_CyFunctionObject *) self);
}
static PyObject *
__pyx_FusedFunction_descr_get(PyObject *self, PyObject *obj, PyObject *type)
{
    __pyx_FusedFunctionObject *func, *meth;
    func = (__pyx_FusedFunctionObject *) self;
    if (func->self || func->func.flags & __Pyx_CYFUNCTION_STATICMETHOD) {
        Py_INCREF(self);
        return self;
    }
    if (obj == Py_None)
        obj = NULL;
    meth = (__pyx_FusedFunctionObject *) __pyx_FusedFunction_NewEx(
                    ((PyCFunctionObject *) func)->m_ml,
                    ((__pyx_CyFunctionObject *) func)->flags,
                    ((__pyx_CyFunctionObject *) func)->func_qualname,
                    ((__pyx_CyFunctionObject *) func)->func_closure,
                    ((PyCFunctionObject *) func)->m_module,
                    ((__pyx_CyFunctionObject *) func)->func_globals,
                    ((__pyx_CyFunctionObject *) func)->func_code);
    if (!meth)
        return NULL;
    Py_XINCREF(func->func.func_classobj);
    meth->func.func_classobj = func->func.func_classobj;
    Py_XINCREF(func->__signatures__);
    meth->__signatures__ = func->__signatures__;
    Py_XINCREF(type);
    meth->type = type;
    Py_XINCREF(func->func.defaults_tuple);
    meth->func.defaults_tuple = func->func.defaults_tuple;
    if (func->func.flags & __Pyx_CYFUNCTION_CLASSMETHOD)
        obj = type;
    Py_XINCREF(obj);
    meth->self = obj;
    return (PyObject *) meth;
}
static PyObject *
_obj_to_str(PyObject *obj)
{
    if (PyType_Check(obj))
        return PyObject_GetAttr(obj, __pyx_n_s_name_2);
    else
        return PyObject_Str(obj);
}
static PyObject *
__pyx_FusedFunction_getitem(__pyx_FusedFunctionObject *self, PyObject *idx)
{
    PyObject *signature = NULL;
    PyObject *unbound_result_func;
    PyObject *result_func = NULL;
    if (self->__signatures__ == NULL) {
        PyErr_SetString(PyExc_TypeError, "Function is not fused");
        return NULL;
    }
    if (PyTuple_Check(idx)) {
        PyObject *list = PyList_New(0);
        Py_ssize_t n = PyTuple_GET_SIZE(idx);
        PyObject *string = NULL;
        PyObject *sep = NULL;
        int i;
        if (!list)
            return NULL;
        for (i = 0; i < n; i++) {
#if CYTHON_ASSUME_SAFE_MACROS && !CYTHON_AVOID_BORROWED_REFS
            PyObject *item = PyTuple_GET_ITEM(idx, i);
#else
            PyObject *item = PySequence_ITEM(idx, i);
#endif
            string = _obj_to_str(item);
#if !(CYTHON_ASSUME_SAFE_MACROS && !CYTHON_AVOID_BORROWED_REFS)
            Py_DECREF(item);
#endif
            if (!string || PyList_Append(list, string) < 0)
                goto __pyx_err;
            Py_DECREF(string);
        }
        sep = PyUnicode_FromString("|");
        if (sep)
            signature = PyUnicode_Join(sep, list);
__pyx_err:
;
        Py_DECREF(list);
        Py_XDECREF(sep);
    } else {
        signature = _obj_to_str(idx);
    }
    if (!signature)
        return NULL;
    unbound_result_func = PyObject_GetItem(self->__signatures__, signature);
    if (unbound_result_func) {
        if (self->self || self->type) {
            __pyx_FusedFunctionObject *unbound = (__pyx_FusedFunctionObject *) unbound_result_func;
            Py_CLEAR(unbound->func.func_classobj);
            Py_XINCREF(self->func.func_classobj);
            unbound->func.func_classobj = self->func.func_classobj;
            result_func = __pyx_FusedFunction_descr_get(unbound_result_func,
                                                        self->self, self->type);
        } else {
            result_func = unbound_result_func;
            Py_INCREF(result_func);
        }
    }
    Py_DECREF(signature);
    Py_XDECREF(unbound_result_func);
    return result_func;
}
static PyObject *
__pyx_FusedFunction_callfunction(PyObject *func, PyObject *args, PyObject *kw)
{
     __pyx_CyFunctionObject *cyfunc = (__pyx_CyFunctionObject *) func;
    int static_specialized = (cyfunc->flags & __Pyx_CYFUNCTION_STATICMETHOD &&
                              !((__pyx_FusedFunctionObject *) func)->__signatures__);
    if (cyfunc->flags & __Pyx_CYFUNCTION_CCLASS && !static_specialized) {
        return __Pyx_CyFunction_CallAsMethod(func, args, kw);
    } else {
        return __Pyx_CyFunction_Call(func, args, kw);
    }
}
static PyObject *
__pyx_FusedFunction_call(PyObject *func, PyObject *args, PyObject *kw)
{
    __pyx_FusedFunctionObject *binding_func = (__pyx_FusedFunctionObject *) func;
    Py_ssize_t argc = PyTuple_GET_SIZE(args);
    PyObject *new_args = NULL;
    __pyx_FusedFunctionObject *new_func = NULL;
    PyObject *result = NULL;
    PyObject *self = NULL;
    int is_staticmethod = binding_func->func.flags & __Pyx_CYFUNCTION_STATICMETHOD;
    int is_classmethod = binding_func->func.flags & __Pyx_CYFUNCTION_CLASSMETHOD;
    if (binding_func->self) {
        Py_ssize_t i;
        new_args = PyTuple_New(argc + 1);
        if (!new_args)
            return NULL;
        self = binding_func->self;
#if !(CYTHON_ASSUME_SAFE_MACROS && !CYTHON_AVOID_BORROWED_REFS)
        Py_INCREF(self);
#endif
        Py_INCREF(self);
        PyTuple_SET_ITEM(new_args, 0, self);
        for (i = 0; i < argc; i++) {
#if CYTHON_ASSUME_SAFE_MACROS && !CYTHON_AVOID_BORROWED_REFS
            PyObject *item = PyTuple_GET_ITEM(args, i);
            Py_INCREF(item);
#else
            PyObject *item = PySequence_ITEM(args, i);  if (unlikely(!item)) goto bad;
#endif
            PyTuple_SET_ITEM(new_args, i + 1, item);
        }
        args = new_args;
    } else if (binding_func->type) {
        if (argc < 1) {
            PyErr_SetString(PyExc_TypeError, "Need at least one argument, 0 given.");
            return NULL;
        }
#if CYTHON_ASSUME_SAFE_MACROS && !CYTHON_AVOID_BORROWED_REFS
        self = PyTuple_GET_ITEM(args, 0);
#else
        self = PySequence_ITEM(args, 0);  if (unlikely(!self)) return NULL;
#endif
    }
    if (self && !is_classmethod && !is_staticmethod) {
        int is_instance = PyObject_IsInstance(self, binding_func->type);
        if (unlikely(!is_instance)) {
            PyErr_Format(PyExc_TypeError,
                         "First argument should be of type %.200s, got %.200s.",
                         ((PyTypeObject *) binding_func->type)->tp_name,
                         self->ob_type->tp_name);
            goto bad;
        } else if (unlikely(is_instance == -1)) {
            goto bad;
        }
    }
#if !(CYTHON_ASSUME_SAFE_MACROS && !CYTHON_AVOID_BORROWED_REFS)
    Py_XDECREF(self);
    self = NULL;
#endif
    if (binding_func->__signatures__) {
        PyObject *tup;
        if (is_staticmethod && binding_func->func.flags & __Pyx_CYFUNCTION_CCLASS) {
            tup = PyTuple_Pack(3, args,
                               kw == NULL ? Py_None : kw,
                               binding_func->func.defaults_tuple);
            if (unlikely(!tup)) goto bad;
            new_func = (__pyx_FusedFunctionObject *) __Pyx_CyFunction_CallMethod(
                func, binding_func->__signatures__, tup, NULL);
        } else {
            tup = PyTuple_Pack(4, binding_func->__signatures__, args,
                               kw == NULL ? Py_None : kw,
                               binding_func->func.defaults_tuple);
            if (unlikely(!tup)) goto bad;
            new_func = (__pyx_FusedFunctionObject *) __pyx_FusedFunction_callfunction(func, tup, NULL);
        }
        Py_DECREF(tup);
        if (unlikely(!new_func))
            goto bad;
        Py_XINCREF(binding_func->func.func_classobj);
        Py_CLEAR(new_func->func.func_classobj);
        new_func->func.func_classobj = binding_func->func.func_classobj;
        func = (PyObject *) new_func;
    }
    result = __pyx_FusedFunction_callfunction(func, args, kw);
bad:
#if !(CYTHON_ASSUME_SAFE_MACROS && !CYTHON_AVOID_BORROWED_REFS)
    Py_XDECREF(self);
#endif
    Py_XDECREF(new_args);
    Py_XDECREF((PyObject *) new_func);
    return result;
}
static PyMemberDef __pyx_FusedFunction_members[] = {
    {(char *) "__signatures__",
     T_OBJECT,
     offsetof(__pyx_FusedFunctionObject, __signatures__),
     READONLY,
     0},
    {0, 0, 0, 0, 0},
};
static PyMappingMethods __pyx_FusedFunction_mapping_methods = {
    0,
    (binaryfunc) __pyx_FusedFunction_getitem,
    0,
};
static PyTypeObject __pyx_FusedFunctionType_type = {
    PyVarObject_HEAD_INIT(0, 0)
    "fused_cython_function",
    sizeof(__pyx_FusedFunctionObject),
    0,
    (destructor) __pyx_FusedFunction_dealloc,
    0,
    0,
    0,
#if PY_MAJOR_VERSION < 3
    0,
#else
    0,
#endif
    0,
    0,
    0,
    &__pyx_FusedFunction_mapping_methods,
    0,
    (ternaryfunc) __pyx_FusedFunction_call,
    0,
    0,
    0,
    0,
    Py_TPFLAGS_DEFAULT | Py_TPFLAGS_HAVE_GC | Py_TPFLAGS_BASETYPE,
    0,
    (traverseproc) __pyx_FusedFunction_traverse,
    (inquiry) __pyx_FusedFunction_clear,
    0,
    0,
    0,
    0,
    0,
    __pyx_FusedFunction_members,
    __pyx_CyFunction_getsets,
    &__pyx_CyFunctionType_type,
    0,
    __pyx_FusedFunction_descr_get,
    0,
    0,
    0,
    0,
    0,
    0,
    0,
    0,
    0,
    0,
    0,
    0,
    0,
    0,
#if PY_VERSION_HEX >= 0x030400a1
    0,
#endif
#if PY_VERSION_HEX >= 0x030800b1
    0,
#endif
#if PY_VERSION_HEX >= 0x030800b4 && PY_VERSION_HEX < 0x03090000
    0,
#endif
};
static int __pyx_FusedFunction_init(void) {
    __pyx_FusedFunctionType = __Pyx_FetchCommonType(&__pyx_FusedFunctionType_type);
    if (__pyx_FusedFunctionType == NULL) {
        return -1;
    }
    return 0;
}

/* CalculateMetaclass */
  static PyObject *__Pyx_CalculateMetaclass(PyTypeObject *metaclass, PyObject *bases) {
    Py_ssize_t i, nbases = PyTuple_GET_SIZE(bases);
    for (i=0; i < nbases; i++) {
        PyTypeObject *tmptype;
        PyObject *tmp = PyTuple_GET_ITEM(bases, i);
        tmptype = Py_TYPE(tmp);
#if PY_MAJOR_VERSION < 3
        if (tmptype == &PyClass_Type)
            continue;
#endif
        if (!metaclass) {
            metaclass = tmptype;
            continue;
        }
        if (PyType_IsSubtype(metaclass, tmptype))
            continue;
        if (PyType_IsSubtype(tmptype, metaclass)) {
            metaclass = tmptype;
            continue;
        }
        PyErr_SetString(PyExc_TypeError,
                        "metaclass conflict: "
                        "the metaclass of a derived class "
                        "must be a (non-strict) subclass "
                        "of the metaclasses of all its bases");
        return NULL;
    }
    if (!metaclass) {
#if PY_MAJOR_VERSION < 3
        metaclass = &PyClass_Type;
#else
        metaclass = &PyType_Type;
#endif
    }
    Py_INCREF((PyObject*) metaclass);
    return (PyObject*) metaclass;
}

/* Py3ClassCreate */
  static PyObject *__Pyx_Py3MetaclassPrepare(PyObject *metaclass, PyObject *bases, PyObject *name,
                                           PyObject *qualname, PyObject *mkw, PyObject *modname, PyObject *doc) {
    PyObject *ns;
    if (metaclass) {
        PyObject *prep = __Pyx_PyObject_GetAttrStr(metaclass, __pyx_n_s_prepare);
        if (prep) {
            PyObject *pargs = PyTuple_Pack(2, name, bases);
            if (unlikely(!pargs)) {
                Py_DECREF(prep);
                return NULL;
            }
            ns = PyObject_Call(prep, pargs, mkw);
            Py_DECREF(prep);
            Py_DECREF(pargs);
        } else {
            if (unlikely(!PyErr_ExceptionMatches(PyExc_AttributeError)))
                return NULL;
            PyErr_Clear();
            ns = PyDict_New();
        }
    } else {
        ns = PyDict_New();
    }
    if (unlikely(!ns))
        return NULL;
    if (unlikely(PyObject_SetItem(ns, __pyx_n_s_module, modname) < 0)) goto bad;
    if (unlikely(PyObject_SetItem(ns, __pyx_n_s_qualname, qualname) < 0)) goto bad;
    if (unlikely(doc && PyObject_SetItem(ns, __pyx_n_s_doc, doc) < 0)) goto bad;
    return ns;
bad:
    Py_DECREF(ns);
    return NULL;
}
static PyObject *__Pyx_Py3ClassCreate(PyObject *metaclass, PyObject *name, PyObject *bases,
                                      PyObject *dict, PyObject *mkw,
                                      int calculate_metaclass, int allow_py2_metaclass) {
    PyObject *result, *margs;
    PyObject *owned_metaclass = NULL;
    if (allow_py2_metaclass) {
        owned_metaclass = PyObject_GetItem(dict, __pyx_n_s_metaclass);
        if (owned_metaclass) {
            metaclass = owned_metaclass;
        } else if (likely(PyErr_ExceptionMatches(PyExc_KeyError))) {
            PyErr_Clear();
        } else {
            return NULL;
        }
    }
    if (calculate_metaclass && (!metaclass || PyType_Check(metaclass))) {
        metaclass = __Pyx_CalculateMetaclass((PyTypeObject*) metaclass, bases);
        Py_XDECREF(owned_metaclass);
        if (unlikely(!metaclass))
            return NULL;
        owned_metaclass = metaclass;
    }
    margs = PyTuple_Pack(3, name, bases, dict);
    if (unlikely(!margs)) {
        result = NULL;
    } else {
        result = PyObject_Call(metaclass, margs, mkw);
        Py_DECREF(margs);
    }
    Py_XDECREF(owned_metaclass);
    return result;
}

/* Globals */
  static PyObject* __Pyx_Globals(void) {
    Py_ssize_t i;
    PyObject *names;
    PyObject *globals = __pyx_d;
    Py_INCREF(globals);
    names = PyObject_Dir(__pyx_m);
    if (!names)
        goto bad;
    for (i = PyList_GET_SIZE(names)-1; i >= 0; i--) {
#if CYTHON_COMPILING_IN_PYPY
        PyObject* name = PySequence_ITEM(names, i);
        if (!name)
            goto bad;
#else
        PyObject* name = PyList_GET_ITEM(names, i);
#endif
        if (!PyDict_Contains(globals, name)) {
            PyObject* value = __Pyx_GetAttr(__pyx_m, name);
            if (!value) {
#if CYTHON_COMPILING_IN_PYPY
                Py_DECREF(name);
#endif
                goto bad;
            }
            if (PyDict_SetItem(globals, name, value) < 0) {
#if CYTHON_COMPILING_IN_PYPY
                Py_DECREF(name);
#endif
                Py_DECREF(value);
                goto bad;
            }
        }
#if CYTHON_COMPILING_IN_PYPY
        Py_DECREF(name);
#endif
    }
    Py_DECREF(names);
    return globals;
bad:
    Py_XDECREF(names);
    Py_XDECREF(globals);
    return NULL;
}

/* CLineInTraceback */
  #ifndef CYTHON_CLINE_IN_TRACEBACK
static int __Pyx_CLineForTraceback(PyThreadState *tstate, int c_line) {
    PyObject *use_cline;
    PyObject *ptype, *pvalue, *ptraceback;
#if CYTHON_COMPILING_IN_CPYTHON
    PyObject **cython_runtime_dict;
#endif
    if (unlikely(!__pyx_cython_runtime)) {
        return c_line;
    }
    __Pyx_ErrFetchInState(tstate, &ptype, &pvalue, &ptraceback);
#if CYTHON_COMPILING_IN_CPYTHON
    cython_runtime_dict = _PyObject_GetDictPtr(__pyx_cython_runtime);
    if (likely(cython_runtime_dict)) {
        __PYX_PY_DICT_LOOKUP_IF_MODIFIED(
            use_cline, *cython_runtime_dict,
            __Pyx_PyDict_GetItemStr(*cython_runtime_dict, __pyx_n_s_cline_in_traceback))
    } else
#endif
    {
      PyObject *use_cline_obj = __Pyx_PyObject_GetAttrStr(__pyx_cython_runtime, __pyx_n_s_cline_in_traceback);
      if (use_cline_obj) {
        use_cline = PyObject_Not(use_cline_obj) ? Py_False : Py_True;
        Py_DECREF(use_cline_obj);
      } else {
        PyErr_Clear();
        use_cline = NULL;
      }
    }
    if (!use_cline) {
        c_line = 0;
        PyObject_SetAttr(__pyx_cython_runtime, __pyx_n_s_cline_in_traceback, Py_False);
    }
    else if (use_cline == Py_False || (use_cline != Py_True && PyObject_Not(use_cline) != 0)) {
        c_line = 0;
    }
    __Pyx_ErrRestoreInState(tstate, ptype, pvalue, ptraceback);
    return c_line;
}
#endif

/* CodeObjectCache */
  static int __pyx_bisect_code_objects(__Pyx_CodeObjectCacheEntry* entries, int count, int code_line) {
    int start = 0, mid = 0, end = count - 1;
    if (end >= 0 && code_line > entries[end].code_line) {
        return count;
    }
    while (start < end) {
        mid = start + (end - start) / 2;
        if (code_line < entries[mid].code_line) {
            end = mid;
        } else if (code_line > entries[mid].code_line) {
             start = mid + 1;
        } else {
            return mid;
        }
    }
    if (code_line <= entries[mid].code_line) {
        return mid;
    } else {
        return mid + 1;
    }
}
static PyCodeObject *__pyx_find_code_object(int code_line) {
    PyCodeObject* code_object;
    int pos;
    if (unlikely(!code_line) || unlikely(!__pyx_code_cache.entries)) {
        return NULL;
    }
    pos = __pyx_bisect_code_objects(__pyx_code_cache.entries, __pyx_code_cache.count, code_line);
    if (unlikely(pos >= __pyx_code_cache.count) || unlikely(__pyx_code_cache.entries[pos].code_line != code_line)) {
        return NULL;
    }
    code_object = __pyx_code_cache.entries[pos].code_object;
    Py_INCREF(code_object);
    return code_object;
}
static void __pyx_insert_code_object(int code_line, PyCodeObject* code_object) {
    int pos, i;
    __Pyx_CodeObjectCacheEntry* entries = __pyx_code_cache.entries;
    if (unlikely(!code_line)) {
        return;
    }
    if (unlikely(!entries)) {
        entries = (__Pyx_CodeObjectCacheEntry*)PyMem_Malloc(64*sizeof(__Pyx_CodeObjectCacheEntry));
        if (likely(entries)) {
            __pyx_code_cache.entries = entries;
            __pyx_code_cache.max_count = 64;
            __pyx_code_cache.count = 1;
            entries[0].code_line = code_line;
            entries[0].code_object = code_object;
            Py_INCREF(code_object);
        }
        return;
    }
    pos = __pyx_bisect_code_objects(__pyx_code_cache.entries, __pyx_code_cache.count, code_line);
    if ((pos < __pyx_code_cache.count) && unlikely(__pyx_code_cache.entries[pos].code_line == code_line)) {
        PyCodeObject* tmp = entries[pos].code_object;
        entries[pos].code_object = code_object;
        Py_DECREF(tmp);
        return;
    }
    if (__pyx_code_cache.count == __pyx_code_cache.max_count) {
        int new_max = __pyx_code_cache.max_count + 64;
        entries = (__Pyx_CodeObjectCacheEntry*)PyMem_Realloc(
            __pyx_code_cache.entries, (size_t)new_max*sizeof(__Pyx_CodeObjectCacheEntry));
        if (unlikely(!entries)) {
            return;
        }
        __pyx_code_cache.entries = entries;
        __pyx_code_cache.max_count = new_max;
    }
    for (i=__pyx_code_cache.count; i>pos; i--) {
        entries[i] = entries[i-1];
    }
    entries[pos].code_line = code_line;
    entries[pos].code_object = code_object;
    __pyx_code_cache.count++;
    Py_INCREF(code_object);
}

/* AddTraceback */
  #include "compile.h"
#include "frameobject.h"
#include "traceback.h"
static PyCodeObject* __Pyx_CreateCodeObjectForTraceback(
            const char *funcname, int c_line,
            int py_line, const char *filename) {
    PyCodeObject *py_code = 0;
    PyObject *py_srcfile = 0;
    PyObject *py_funcname = 0;
    #if PY_MAJOR_VERSION < 3
    py_srcfile = PyString_FromString(filename);
    #else
    py_srcfile = PyUnicode_FromString(filename);
    #endif
    if (!py_srcfile) goto bad;
    if (c_line) {
        #if PY_MAJOR_VERSION < 3
        py_funcname = PyString_FromFormat( "%s (%s:%d)", funcname, __pyx_cfilenm, c_line);
        #else
        py_funcname = PyUnicode_FromFormat( "%s (%s:%d)", funcname, __pyx_cfilenm, c_line);
        #endif
    }
    else {
        #if PY_MAJOR_VERSION < 3
        py_funcname = PyString_FromString(funcname);
        #else
        py_funcname = PyUnicode_FromString(funcname);
        #endif
    }
    if (!py_funcname) goto bad;
    py_code = __Pyx_PyCode_New(
        0,
        0,
        0,
        0,
        0,
        __pyx_empty_bytes, /*PyObject *code,*/
        __pyx_empty_tuple, /*PyObject *consts,*/
        __pyx_empty_tuple, /*PyObject *names,*/
        __pyx_empty_tuple, /*PyObject *varnames,*/
        __pyx_empty_tuple, /*PyObject *freevars,*/
        __pyx_empty_tuple, /*PyObject *cellvars,*/
        py_srcfile,   /*PyObject *filename,*/
        py_funcname,  /*PyObject *name,*/
        py_line,
        __pyx_empty_bytes  /*PyObject *lnotab*/
    );
    Py_DECREF(py_srcfile);
    Py_DECREF(py_funcname);
    return py_code;
bad:
    Py_XDECREF(py_srcfile);
    Py_XDECREF(py_funcname);
    return NULL;
}
static void __Pyx_AddTraceback(const char *funcname, int c_line,
                               int py_line, const char *filename) {
    PyCodeObject *py_code = 0;
    PyFrameObject *py_frame = 0;
    PyThreadState *tstate = __Pyx_PyThreadState_Current;
    if (c_line) {
        c_line = __Pyx_CLineForTraceback(tstate, c_line);
    }
    py_code = __pyx_find_code_object(c_line ? -c_line : py_line);
    if (!py_code) {
        py_code = __Pyx_CreateCodeObjectForTraceback(
            funcname, c_line, py_line, filename);
        if (!py_code) goto bad;
        __pyx_insert_code_object(c_line ? -c_line : py_line, py_code);
    }
    py_frame = PyFrame_New(
        tstate,            /*PyThreadState *tstate,*/
        py_code,           /*PyCodeObject *code,*/
        __pyx_d,    /*PyObject *globals,*/
        0                  /*PyObject *locals*/
    );
    if (!py_frame) goto bad;
    __Pyx_PyFrame_SetLineNumber(py_frame, py_line);
    PyTraceBack_Here(py_frame);
bad:
    Py_XDECREF(py_code);
    Py_XDECREF(py_frame);
}

/* CIntToPy */
  static CYTHON_INLINE PyObject* __Pyx_PyInt_From_enum____pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType(enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType value) {
    const enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType neg_one = (enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType) ((enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType) 0 - (enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType) 1), const_zero = (enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType) 0;
    const int is_unsigned = neg_one > const_zero;
    if (is_unsigned) {
        if (sizeof(enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType) < sizeof(long)) {
            return PyInt_FromLong((long) value);
        } else if (sizeof(enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType) <= sizeof(unsigned long)) {
            return PyLong_FromUnsignedLong((unsigned long) value);
#ifdef HAVE_LONG_LONG
        } else if (sizeof(enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType) <= sizeof(unsigned PY_LONG_LONG)) {
            return PyLong_FromUnsignedLongLong((unsigned PY_LONG_LONG) value);
#endif
        }
    } else {
        if (sizeof(enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType) <= sizeof(long)) {
            return PyInt_FromLong((long) value);
#ifdef HAVE_LONG_LONG
        } else if (sizeof(enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType) <= sizeof(PY_LONG_LONG)) {
            return PyLong_FromLongLong((PY_LONG_LONG) value);
#endif
        }
    }
    {
        int one = 1; int little = (int)*(unsigned char *)&one;
        unsigned char *bytes = (unsigned char *)&value;
        return _PyLong_FromByteArray(bytes, sizeof(enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType),
                                     little, !is_unsigned);
    }
}

/* CIntFromPyVerify */
  #define __PYX_VERIFY_RETURN_INT(target_type, func_type, func_value)\
    __PYX__VERIFY_RETURN_INT(target_type, func_type, func_value, 0)
#define __PYX_VERIFY_RETURN_INT_EXC(target_type, func_type, func_value)\
    __PYX__VERIFY_RETURN_INT(target_type, func_type, func_value, 1)
#define __PYX__VERIFY_RETURN_INT(target_type, func_type, func_value, exc)\
    {\
        func_type value = func_value;\
        if (sizeof(target_type) < sizeof(func_type)) {\
            if (unlikely(value != (func_type) (target_type) value)) {\
                func_type zero = 0;\
                if (exc && unlikely(value == (func_type)-1 && PyErr_Occurred()))\
                    return (target_type) -1;\
                if (is_unsigned && unlikely(value < zero))\
                    goto raise_neg_overflow;\
                else\
                    goto raise_overflow;\
            }\
        }\
        return (target_type) value;\
    }

#if PY_MAJOR_VERSION < 3
static int __Pyx_GetBuffer(PyObject *obj, Py_buffer *view, int flags) {
    if (PyObject_CheckBuffer(obj)) return PyObject_GetBuffer(obj, view, flags);
        if (__Pyx_TypeCheck(obj, __pyx_ptype_5numpy_ndarray)) return __pyx_pw_5numpy_7ndarray_1__getbuffer__(obj, view, flags);
    PyErr_Format(PyExc_TypeError, "'%.200s' does not have the buffer interface", Py_TYPE(obj)->tp_name);
    return -1;
}
static void __Pyx_ReleaseBuffer(Py_buffer *view) {
    PyObject *obj = view->obj;
    if (!obj) return;
    if (PyObject_CheckBuffer(obj)) {
        PyBuffer_Release(view);
        return;
    }
    if ((0)) {}
        else if (__Pyx_TypeCheck(obj, __pyx_ptype_5numpy_ndarray)) __pyx_pw_5numpy_7ndarray_3__releasebuffer__(obj, view);
    view->obj = NULL;
    Py_DECREF(obj);
}
#endif


  /* CIntToPy */
  static CYTHON_INLINE PyObject* __Pyx_PyInt_From_long(long value) {
    const long neg_one = (long) ((long) 0 - (long) 1), const_zero = (long) 0;
    const int is_unsigned = neg_one > const_zero;
    if (is_unsigned) {
        if (sizeof(long) < sizeof(long)) {
            return PyInt_FromLong((long) value);
        } else if (sizeof(long) <= sizeof(unsigned long)) {
            return PyLong_FromUnsignedLong((unsigned long) value);
#ifdef HAVE_LONG_LONG
        } else if (sizeof(long) <= sizeof(unsigned PY_LONG_LONG)) {
            return PyLong_FromUnsignedLongLong((unsigned PY_LONG_LONG) value);
#endif
        }
    } else {
        if (sizeof(long) <= sizeof(long)) {
            return PyInt_FromLong((long) value);
#ifdef HAVE_LONG_LONG
        } else if (sizeof(long) <= sizeof(PY_LONG_LONG)) {
            return PyLong_FromLongLong((PY_LONG_LONG) value);
#endif
        }
    }
    {
        int one = 1; int little = (int)*(unsigned char *)&one;
        unsigned char *bytes = (unsigned char *)&value;
        return _PyLong_FromByteArray(bytes, sizeof(long),
                                     little, !is_unsigned);
    }
}

/* None */
  static CYTHON_INLINE long __Pyx_pow_long(long b, long e) {
    long t = b;
    switch (e) {
        case 3:
            t *= b;
        CYTHON_FALLTHROUGH;
        case 2:
            t *= b;
        CYTHON_FALLTHROUGH;
        case 1:
            return t;
        case 0:
            return 1;
    }
    #if 1
    if (unlikely(e<0)) return 0;
    #endif
    t = 1;
    while (likely(e)) {
        t *= (b * (e&1)) | ((~e)&1);
        b *= b;
        e >>= 1;
    }
    return t;
}

/* CIntToPy */
  static CYTHON_INLINE PyObject* __Pyx_PyInt_From_int(int value) {
    const int neg_one = (int) ((int) 0 - (int) 1), const_zero = (int) 0;
    const int is_unsigned = neg_one > const_zero;
    if (is_unsigned) {
        if (sizeof(int) < sizeof(long)) {
            return PyInt_FromLong((long) value);
        } else if (sizeof(int) <= sizeof(unsigned long)) {
            return PyLong_FromUnsignedLong((unsigned long) value);
#ifdef HAVE_LONG_LONG
        } else if (sizeof(int) <= sizeof(unsigned PY_LONG_LONG)) {
            return PyLong_FromUnsignedLongLong((unsigned PY_LONG_LONG) value);
#endif
        }
    } else {
        if (sizeof(int) <= sizeof(long)) {
            return PyInt_FromLong((long) value);
#ifdef HAVE_LONG_LONG
        } else if (sizeof(int) <= sizeof(PY_LONG_LONG)) {
            return PyLong_FromLongLong((PY_LONG_LONG) value);
#endif
        }
    }
    {
        int one = 1; int little = (int)*(unsigned char *)&one;
        unsigned char *bytes = (unsigned char *)&value;
        return _PyLong_FromByteArray(bytes, sizeof(int),
                                     little, !is_unsigned);
    }
}

/* Declarations */
  #if CYTHON_CCOMPLEX
  #ifdef __cplusplus
    static CYTHON_INLINE __pyx_t_float_complex __pyx_t_float_complex_from_parts(float x, float y) {
      return ::std::complex< float >(x, y);
    }
  #else
    static CYTHON_INLINE __pyx_t_float_complex __pyx_t_float_complex_from_parts(float x, float y) {
      return x + y*(__pyx_t_float_complex)_Complex_I;
    }
  #endif
#else
    static CYTHON_INLINE __pyx_t_float_complex __pyx_t_float_complex_from_parts(float x, float y) {
      __pyx_t_float_complex z;
      z.real = x;
      z.imag = y;
      return z;
    }
#endif

/* Arithmetic */
  #if CYTHON_CCOMPLEX
#else
    static CYTHON_INLINE int __Pyx_c_eq_float(__pyx_t_float_complex a, __pyx_t_float_complex b) {
       return (a.real == b.real) && (a.imag == b.imag);
    }
    static CYTHON_INLINE __pyx_t_float_complex __Pyx_c_sum_float(__pyx_t_float_complex a, __pyx_t_float_complex b) {
        __pyx_t_float_complex z;
        z.real = a.real + b.real;
        z.imag = a.imag + b.imag;
        return z;
    }
    static CYTHON_INLINE __pyx_t_float_complex __Pyx_c_diff_float(__pyx_t_float_complex a, __pyx_t_float_complex b) {
        __pyx_t_float_complex z;
        z.real = a.real - b.real;
        z.imag = a.imag - b.imag;
        return z;
    }
    static CYTHON_INLINE __pyx_t_float_complex __Pyx_c_prod_float(__pyx_t_float_complex a, __pyx_t_float_complex b) {
        __pyx_t_float_complex z;
        z.real = a.real * b.real - a.imag * b.imag;
        z.imag = a.real * b.imag + a.imag * b.real;
        return z;
    }
    #if 1
    static CYTHON_INLINE __pyx_t_float_complex __Pyx_c_quot_float(__pyx_t_float_complex a, __pyx_t_float_complex b) {
        if (b.imag == 0) {
            return __pyx_t_float_complex_from_parts(a.real / b.real, a.imag / b.real);
        } else if (fabsf(b.real) >= fabsf(b.imag)) {
            if (b.real == 0 && b.imag == 0) {
                return __pyx_t_float_complex_from_parts(a.real / b.real, a.imag / b.imag);
            } else {
                float r = b.imag / b.real;
                float s = (float)(1.0) / (b.real + b.imag * r);
                return __pyx_t_float_complex_from_parts(
                    (a.real + a.imag * r) * s, (a.imag - a.real * r) * s);
            }
        } else {
            float r = b.real / b.imag;
            float s = (float)(1.0) / (b.imag + b.real * r);
            return __pyx_t_float_complex_from_parts(
                (a.real * r + a.imag) * s, (a.imag * r - a.real) * s);
        }
    }
    #else
    static CYTHON_INLINE __pyx_t_float_complex __Pyx_c_quot_float(__pyx_t_float_complex a, __pyx_t_float_complex b) {
        if (b.imag == 0) {
            return __pyx_t_float_complex_from_parts(a.real / b.real, a.imag / b.real);
        } else {
            float denom = b.real * b.real + b.imag * b.imag;
            return __pyx_t_float_complex_from_parts(
                (a.real * b.real + a.imag * b.imag) / denom,
                (a.imag * b.real - a.real * b.imag) / denom);
        }
    }
    #endif
    static CYTHON_INLINE __pyx_t_float_complex __Pyx_c_neg_float(__pyx_t_float_complex a) {
        __pyx_t_float_complex z;
        z.real = -a.real;
        z.imag = -a.imag;
        return z;
    }
    static CYTHON_INLINE int __Pyx_c_is_zero_float(__pyx_t_float_complex a) {
       return (a.real == 0) && (a.imag == 0);
    }
    static CYTHON_INLINE __pyx_t_float_complex __Pyx_c_conj_float(__pyx_t_float_complex a) {
        __pyx_t_float_complex z;
        z.real =  a.real;
        z.imag = -a.imag;
        return z;
    }
    #if 1
        static CYTHON_INLINE float __Pyx_c_abs_float(__pyx_t_float_complex z) {
          #if !defined(HAVE_HYPOT) || defined(_MSC_VER)
            return sqrtf(z.real*z.real + z.imag*z.imag);
          #else
            return hypotf(z.real, z.imag);
          #endif
        }
        static CYTHON_INLINE __pyx_t_float_complex __Pyx_c_pow_float(__pyx_t_float_complex a, __pyx_t_float_complex b) {
            __pyx_t_float_complex z;
            float r, lnr, theta, z_r, z_theta;
            if (b.imag == 0 && b.real == (int)b.real) {
                if (b.real < 0) {
                    float denom = a.real * a.real + a.imag * a.imag;
                    a.real = a.real / denom;
                    a.imag = -a.imag / denom;
                    b.real = -b.real;
                }
                switch ((int)b.real) {
                    case 0:
                        z.real = 1;
                        z.imag = 0;
                        return z;
                    case 1:
                        return a;
                    case 2:
                        return __Pyx_c_prod_float(a, a);
                    case 3:
                        z = __Pyx_c_prod_float(a, a);
                        return __Pyx_c_prod_float(z, a);
                    case 4:
                        z = __Pyx_c_prod_float(a, a);
                        return __Pyx_c_prod_float(z, z);
                }
            }
            if (a.imag == 0) {
                if (a.real == 0) {
                    return a;
                } else if (b.imag == 0) {
                    z.real = powf(a.real, b.real);
                    z.imag = 0;
                    return z;
                } else if (a.real > 0) {
                    r = a.real;
                    theta = 0;
                } else {
                    r = -a.real;
                    theta = atan2f(0.0, -1.0);
                }
            } else {
                r = __Pyx_c_abs_float(a);
                theta = atan2f(a.imag, a.real);
            }
            lnr = logf(r);
            z_r = expf(lnr * b.real - theta * b.imag);
            z_theta = theta * b.real + lnr * b.imag;
            z.real = z_r * cosf(z_theta);
            z.imag = z_r * sinf(z_theta);
            return z;
        }
    #endif
#endif

/* Declarations */
  #if CYTHON_CCOMPLEX
  #ifdef __cplusplus
    static CYTHON_INLINE __pyx_t_double_complex __pyx_t_double_complex_from_parts(double x, double y) {
      return ::std::complex< double >(x, y);
    }
  #else
    static CYTHON_INLINE __pyx_t_double_complex __pyx_t_double_complex_from_parts(double x, double y) {
      return x + y*(__pyx_t_double_complex)_Complex_I;
    }
  #endif
#else
    static CYTHON_INLINE __pyx_t_double_complex __pyx_t_double_complex_from_parts(double x, double y) {
      __pyx_t_double_complex z;
      z.real = x;
      z.imag = y;
      return z;
    }
#endif

/* Arithmetic */
  #if CYTHON_CCOMPLEX
#else
    static CYTHON_INLINE int __Pyx_c_eq_double(__pyx_t_double_complex a, __pyx_t_double_complex b) {
       return (a.real == b.real) && (a.imag == b.imag);
    }
    static CYTHON_INLINE __pyx_t_double_complex __Pyx_c_sum_double(__pyx_t_double_complex a, __pyx_t_double_complex b) {
        __pyx_t_double_complex z;
        z.real = a.real + b.real;
        z.imag = a.imag + b.imag;
        return z;
    }
    static CYTHON_INLINE __pyx_t_double_complex __Pyx_c_diff_double(__pyx_t_double_complex a, __pyx_t_double_complex b) {
        __pyx_t_double_complex z;
        z.real = a.real - b.real;
        z.imag = a.imag - b.imag;
        return z;
    }
    static CYTHON_INLINE __pyx_t_double_complex __Pyx_c_prod_double(__pyx_t_double_complex a, __pyx_t_double_complex b) {
        __pyx_t_double_complex z;
        z.real = a.real * b.real - a.imag * b.imag;
        z.imag = a.real * b.imag + a.imag * b.real;
        return z;
    }
    #if 1
    static CYTHON_INLINE __pyx_t_double_complex __Pyx_c_quot_double(__pyx_t_double_complex a, __pyx_t_double_complex b) {
        if (b.imag == 0) {
            return __pyx_t_double_complex_from_parts(a.real / b.real, a.imag / b.real);
        } else if (fabs(b.real) >= fabs(b.imag)) {
            if (b.real == 0 && b.imag == 0) {
                return __pyx_t_double_complex_from_parts(a.real / b.real, a.imag / b.imag);
            } else {
                double r = b.imag / b.real;
                double s = (double)(1.0) / (b.real + b.imag * r);
                return __pyx_t_double_complex_from_parts(
                    (a.real + a.imag * r) * s, (a.imag - a.real * r) * s);
            }
        } else {
            double r = b.real / b.imag;
            double s = (double)(1.0) / (b.imag + b.real * r);
            return __pyx_t_double_complex_from_parts(
                (a.real * r + a.imag) * s, (a.imag * r - a.real) * s);
        }
    }
    #else
    static CYTHON_INLINE __pyx_t_double_complex __Pyx_c_quot_double(__pyx_t_double_complex a, __pyx_t_double_complex b) {
        if (b.imag == 0) {
            return __pyx_t_double_complex_from_parts(a.real / b.real, a.imag / b.real);
        } else {
            double denom = b.real * b.real + b.imag * b.imag;
            return __pyx_t_double_complex_from_parts(
                (a.real * b.real + a.imag * b.imag) / denom,
                (a.imag * b.real - a.real * b.imag) / denom);
        }
    }
    #endif
    static CYTHON_INLINE __pyx_t_double_complex __Pyx_c_neg_double(__pyx_t_double_complex a) {
        __pyx_t_double_complex z;
        z.real = -a.real;
        z.imag = -a.imag;
        return z;
    }
    static CYTHON_INLINE int __Pyx_c_is_zero_double(__pyx_t_double_complex a) {
       return (a.real == 0) && (a.imag == 0);
    }
    static CYTHON_INLINE __pyx_t_double_complex __Pyx_c_conj_double(__pyx_t_double_complex a) {
        __pyx_t_double_complex z;
        z.real =  a.real;
        z.imag = -a.imag;
        return z;
    }
    #if 1
        static CYTHON_INLINE double __Pyx_c_abs_double(__pyx_t_double_complex z) {
          #if !defined(HAVE_HYPOT) || defined(_MSC_VER)
            return sqrt(z.real*z.real + z.imag*z.imag);
          #else
            return hypot(z.real, z.imag);
          #endif
        }
        static CYTHON_INLINE __pyx_t_double_complex __Pyx_c_pow_double(__pyx_t_double_complex a, __pyx_t_double_complex b) {
            __pyx_t_double_complex z;
            double r, lnr, theta, z_r, z_theta;
            if (b.imag == 0 && b.real == (int)b.real) {
                if (b.real < 0) {
                    double denom = a.real * a.real + a.imag * a.imag;
                    a.real = a.real / denom;
                    a.imag = -a.imag / denom;
                    b.real = -b.real;
                }
                switch ((int)b.real) {
                    case 0:
                        z.real = 1;
                        z.imag = 0;
                        return z;
                    case 1:
                        return a;
                    case 2:
                        return __Pyx_c_prod_double(a, a);
                    case 3:
                        z = __Pyx_c_prod_double(a, a);
                        return __Pyx_c_prod_double(z, a);
                    case 4:
                        z = __Pyx_c_prod_double(a, a);
                        return __Pyx_c_prod_double(z, z);
                }
            }
            if (a.imag == 0) {
                if (a.real == 0) {
                    return a;
                } else if (b.imag == 0) {
                    z.real = pow(a.real, b.real);
                    z.imag = 0;
                    return z;
                } else if (a.real > 0) {
                    r = a.real;
                    theta = 0;
                } else {
                    r = -a.real;
                    theta = atan2(0.0, -1.0);
                }
            } else {
                r = __Pyx_c_abs_double(a);
                theta = atan2(a.imag, a.real);
            }
            lnr = log(r);
            z_r = exp(lnr * b.real - theta * b.imag);
            z_theta = theta * b.real + lnr * b.imag;
            z.real = z_r * cos(z_theta);
            z.imag = z_r * sin(z_theta);
            return z;
        }
    #endif
#endif

/* CIntToPy */
  static CYTHON_INLINE PyObject* __Pyx_PyInt_From_enum__NPY_TYPES(enum NPY_TYPES value) {
    const enum NPY_TYPES neg_one = (enum NPY_TYPES) ((enum NPY_TYPES) 0 - (enum NPY_TYPES) 1), const_zero = (enum NPY_TYPES) 0;
    const int is_unsigned = neg_one > const_zero;
    if (is_unsigned) {
        if (sizeof(enum NPY_TYPES) < sizeof(long)) {
            return PyInt_FromLong((long) value);
        } else if (sizeof(enum NPY_TYPES) <= sizeof(unsigned long)) {
            return PyLong_FromUnsignedLong((unsigned long) value);
#ifdef HAVE_LONG_LONG
        } else if (sizeof(enum NPY_TYPES) <= sizeof(unsigned PY_LONG_LONG)) {
            return PyLong_FromUnsignedLongLong((unsigned PY_LONG_LONG) value);
#endif
        }
    } else {
        if (sizeof(enum NPY_TYPES) <= sizeof(long)) {
            return PyInt_FromLong((long) value);
#ifdef HAVE_LONG_LONG
        } else if (sizeof(enum NPY_TYPES) <= sizeof(PY_LONG_LONG)) {
            return PyLong_FromLongLong((PY_LONG_LONG) value);
#endif
        }
    }
    {
        int one = 1; int little = (int)*(unsigned char *)&one;
        unsigned char *bytes = (unsigned char *)&value;
        return _PyLong_FromByteArray(bytes, sizeof(enum NPY_TYPES),
                                     little, !is_unsigned);
    }
}

/* CIntFromPy */
  static CYTHON_INLINE enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType __Pyx_PyInt_As_enum____pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType(PyObject *x) {
    const enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType neg_one = (enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType) ((enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType) 0 - (enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType) 1), const_zero = (enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType) 0;
    const int is_unsigned = neg_one > const_zero;
#if PY_MAJOR_VERSION < 3
    if (likely(PyInt_Check(x))) {
        if (sizeof(enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType) < sizeof(long)) {
            __PYX_VERIFY_RETURN_INT(enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType, long, PyInt_AS_LONG(x))
        } else {
            long val = PyInt_AS_LONG(x);
            if (is_unsigned && unlikely(val < 0)) {
                goto raise_neg_overflow;
            }
            return (enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType) val;
        }
    } else
#endif
    if (likely(PyLong_Check(x))) {
        if (is_unsigned) {
#if CYTHON_USE_PYLONG_INTERNALS
            const digit* digits = ((PyLongObject*)x)->ob_digit;
            switch (Py_SIZE(x)) {
                case  0: return (enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType) 0;
                case  1: __PYX_VERIFY_RETURN_INT(enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType, digit, digits[0])
                case 2:
                    if (8 * sizeof(enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType) > 1 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 2 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType, unsigned long, (((((unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType) >= 2 * PyLong_SHIFT) {
                            return (enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType) (((((enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType)digits[1]) << PyLong_SHIFT) | (enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType)digits[0]));
                        }
                    }
                    break;
                case 3:
                    if (8 * sizeof(enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType) > 2 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 3 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType, unsigned long, (((((((unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType) >= 3 * PyLong_SHIFT) {
                            return (enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType) (((((((enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType)digits[2]) << PyLong_SHIFT) | (enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType)digits[1]) << PyLong_SHIFT) | (enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType)digits[0]));
                        }
                    }
                    break;
                case 4:
                    if (8 * sizeof(enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType) > 3 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 4 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType, unsigned long, (((((((((unsigned long)digits[3]) << PyLong_SHIFT) | (unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType) >= 4 * PyLong_SHIFT) {
                            return (enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType) (((((((((enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType)digits[3]) << PyLong_SHIFT) | (enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType)digits[2]) << PyLong_SHIFT) | (enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType)digits[1]) << PyLong_SHIFT) | (enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType)digits[0]));
                        }
                    }
                    break;
            }
#endif
#if CYTHON_COMPILING_IN_CPYTHON
            if (unlikely(Py_SIZE(x) < 0)) {
                goto raise_neg_overflow;
            }
#else
            {
                int result = PyObject_RichCompareBool(x, Py_False, Py_LT);
                if (unlikely(result < 0))
                    return (enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType) -1;
                if (unlikely(result == 1))
                    goto raise_neg_overflow;
            }
#endif
            if (sizeof(enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType) <= sizeof(unsigned long)) {
                __PYX_VERIFY_RETURN_INT_EXC(enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType, unsigned long, PyLong_AsUnsignedLong(x))
#ifdef HAVE_LONG_LONG
            } else if (sizeof(enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType) <= sizeof(unsigned PY_LONG_LONG)) {
                __PYX_VERIFY_RETURN_INT_EXC(enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType, unsigned PY_LONG_LONG, PyLong_AsUnsignedLongLong(x))
#endif
            }
        } else {
#if CYTHON_USE_PYLONG_INTERNALS
            const digit* digits = ((PyLongObject*)x)->ob_digit;
            switch (Py_SIZE(x)) {
                case  0: return (enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType) 0;
                case -1: __PYX_VERIFY_RETURN_INT(enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType, sdigit, (sdigit) (-(sdigit)digits[0]))
                case  1: __PYX_VERIFY_RETURN_INT(enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType,  digit, +digits[0])
                case -2:
                    if (8 * sizeof(enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType) - 1 > 1 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 2 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType, long, -(long) (((((unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType) - 1 > 2 * PyLong_SHIFT) {
                            return (enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType) (((enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType)-1)*(((((enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType)digits[1]) << PyLong_SHIFT) | (enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType)digits[0])));
                        }
                    }
                    break;
                case 2:
                    if (8 * sizeof(enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType) > 1 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 2 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType, unsigned long, (((((unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType) - 1 > 2 * PyLong_SHIFT) {
                            return (enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType) ((((((enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType)digits[1]) << PyLong_SHIFT) | (enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType)digits[0])));
                        }
                    }
                    break;
                case -3:
                    if (8 * sizeof(enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType) - 1 > 2 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 3 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType, long, -(long) (((((((unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType) - 1 > 3 * PyLong_SHIFT) {
                            return (enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType) (((enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType)-1)*(((((((enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType)digits[2]) << PyLong_SHIFT) | (enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType)digits[1]) << PyLong_SHIFT) | (enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType)digits[0])));
                        }
                    }
                    break;
                case 3:
                    if (8 * sizeof(enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType) > 2 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 3 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType, unsigned long, (((((((unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType) - 1 > 3 * PyLong_SHIFT) {
                            return (enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType) ((((((((enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType)digits[2]) << PyLong_SHIFT) | (enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType)digits[1]) << PyLong_SHIFT) | (enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType)digits[0])));
                        }
                    }
                    break;
                case -4:
                    if (8 * sizeof(enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType) - 1 > 3 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 4 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType, long, -(long) (((((((((unsigned long)digits[3]) << PyLong_SHIFT) | (unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType) - 1 > 4 * PyLong_SHIFT) {
                            return (enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType) (((enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType)-1)*(((((((((enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType)digits[3]) << PyLong_SHIFT) | (enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType)digits[2]) << PyLong_SHIFT) | (enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType)digits[1]) << PyLong_SHIFT) | (enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType)digits[0])));
                        }
                    }
                    break;
                case 4:
                    if (8 * sizeof(enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType) > 3 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 4 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType, unsigned long, (((((((((unsigned long)digits[3]) << PyLong_SHIFT) | (unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType) - 1 > 4 * PyLong_SHIFT) {
                            return (enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType) ((((((((((enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType)digits[3]) << PyLong_SHIFT) | (enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType)digits[2]) << PyLong_SHIFT) | (enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType)digits[1]) << PyLong_SHIFT) | (enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType)digits[0])));
                        }
                    }
                    break;
            }
#endif
            if (sizeof(enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType) <= sizeof(long)) {
                __PYX_VERIFY_RETURN_INT_EXC(enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType, long, PyLong_AsLong(x))
#ifdef HAVE_LONG_LONG
            } else if (sizeof(enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType) <= sizeof(PY_LONG_LONG)) {
                __PYX_VERIFY_RETURN_INT_EXC(enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType, PY_LONG_LONG, PyLong_AsLongLong(x))
#endif
            }
        }
        {
#if CYTHON_COMPILING_IN_PYPY && !defined(_PyLong_AsByteArray)
            PyErr_SetString(PyExc_RuntimeError,
                            "_PyLong_AsByteArray() not available in PyPy, cannot convert large numbers");
#else
            enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType val;
            PyObject *v = __Pyx_PyNumber_IntOrLong(x);
 #if PY_MAJOR_VERSION < 3
            if (likely(v) && !PyLong_Check(v)) {
                PyObject *tmp = v;
                v = PyNumber_Long(tmp);
                Py_DECREF(tmp);
            }
 #endif
            if (likely(v)) {
                int one = 1; int is_little = (int)*(unsigned char *)&one;
                unsigned char *bytes = (unsigned char *)&val;
                int ret = _PyLong_AsByteArray((PyLongObject *)v,
                                              bytes, sizeof(val),
                                              is_little, !is_unsigned);
                Py_DECREF(v);
                if (likely(!ret))
                    return val;
            }
#endif
            return (enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType) -1;
        }
    } else {
        enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType val;
        PyObject *tmp = __Pyx_PyNumber_IntOrLong(x);
        if (!tmp) return (enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType) -1;
        val = __Pyx_PyInt_As_enum____pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType(tmp);
        Py_DECREF(tmp);
        return val;
    }
raise_overflow:
    PyErr_SetString(PyExc_OverflowError,
        "value too large to convert to enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType");
    return (enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType) -1;
raise_neg_overflow:
    PyErr_SetString(PyExc_OverflowError,
        "can't convert negative value to enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType");
    return (enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_PeakType) -1;
}

/* CIntFromPy */
  static CYTHON_INLINE int __Pyx_PyInt_As_int(PyObject *x) {
    const int neg_one = (int) ((int) 0 - (int) 1), const_zero = (int) 0;
    const int is_unsigned = neg_one > const_zero;
#if PY_MAJOR_VERSION < 3
    if (likely(PyInt_Check(x))) {
        if (sizeof(int) < sizeof(long)) {
            __PYX_VERIFY_RETURN_INT(int, long, PyInt_AS_LONG(x))
        } else {
            long val = PyInt_AS_LONG(x);
            if (is_unsigned && unlikely(val < 0)) {
                goto raise_neg_overflow;
            }
            return (int) val;
        }
    } else
#endif
    if (likely(PyLong_Check(x))) {
        if (is_unsigned) {
#if CYTHON_USE_PYLONG_INTERNALS
            const digit* digits = ((PyLongObject*)x)->ob_digit;
            switch (Py_SIZE(x)) {
                case  0: return (int) 0;
                case  1: __PYX_VERIFY_RETURN_INT(int, digit, digits[0])
                case 2:
                    if (8 * sizeof(int) > 1 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 2 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(int, unsigned long, (((((unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(int) >= 2 * PyLong_SHIFT) {
                            return (int) (((((int)digits[1]) << PyLong_SHIFT) | (int)digits[0]));
                        }
                    }
                    break;
                case 3:
                    if (8 * sizeof(int) > 2 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 3 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(int, unsigned long, (((((((unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(int) >= 3 * PyLong_SHIFT) {
                            return (int) (((((((int)digits[2]) << PyLong_SHIFT) | (int)digits[1]) << PyLong_SHIFT) | (int)digits[0]));
                        }
                    }
                    break;
                case 4:
                    if (8 * sizeof(int) > 3 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 4 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(int, unsigned long, (((((((((unsigned long)digits[3]) << PyLong_SHIFT) | (unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(int) >= 4 * PyLong_SHIFT) {
                            return (int) (((((((((int)digits[3]) << PyLong_SHIFT) | (int)digits[2]) << PyLong_SHIFT) | (int)digits[1]) << PyLong_SHIFT) | (int)digits[0]));
                        }
                    }
                    break;
            }
#endif
#if CYTHON_COMPILING_IN_CPYTHON
            if (unlikely(Py_SIZE(x) < 0)) {
                goto raise_neg_overflow;
            }
#else
            {
                int result = PyObject_RichCompareBool(x, Py_False, Py_LT);
                if (unlikely(result < 0))
                    return (int) -1;
                if (unlikely(result == 1))
                    goto raise_neg_overflow;
            }
#endif
            if (sizeof(int) <= sizeof(unsigned long)) {
                __PYX_VERIFY_RETURN_INT_EXC(int, unsigned long, PyLong_AsUnsignedLong(x))
#ifdef HAVE_LONG_LONG
            } else if (sizeof(int) <= sizeof(unsigned PY_LONG_LONG)) {
                __PYX_VERIFY_RETURN_INT_EXC(int, unsigned PY_LONG_LONG, PyLong_AsUnsignedLongLong(x))
#endif
            }
        } else {
#if CYTHON_USE_PYLONG_INTERNALS
            const digit* digits = ((PyLongObject*)x)->ob_digit;
            switch (Py_SIZE(x)) {
                case  0: return (int) 0;
                case -1: __PYX_VERIFY_RETURN_INT(int, sdigit, (sdigit) (-(sdigit)digits[0]))
                case  1: __PYX_VERIFY_RETURN_INT(int,  digit, +digits[0])
                case -2:
                    if (8 * sizeof(int) - 1 > 1 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 2 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(int, long, -(long) (((((unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(int) - 1 > 2 * PyLong_SHIFT) {
                            return (int) (((int)-1)*(((((int)digits[1]) << PyLong_SHIFT) | (int)digits[0])));
                        }
                    }
                    break;
                case 2:
                    if (8 * sizeof(int) > 1 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 2 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(int, unsigned long, (((((unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(int) - 1 > 2 * PyLong_SHIFT) {
                            return (int) ((((((int)digits[1]) << PyLong_SHIFT) | (int)digits[0])));
                        }
                    }
                    break;
                case -3:
                    if (8 * sizeof(int) - 1 > 2 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 3 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(int, long, -(long) (((((((unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(int) - 1 > 3 * PyLong_SHIFT) {
                            return (int) (((int)-1)*(((((((int)digits[2]) << PyLong_SHIFT) | (int)digits[1]) << PyLong_SHIFT) | (int)digits[0])));
                        }
                    }
                    break;
                case 3:
                    if (8 * sizeof(int) > 2 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 3 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(int, unsigned long, (((((((unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(int) - 1 > 3 * PyLong_SHIFT) {
                            return (int) ((((((((int)digits[2]) << PyLong_SHIFT) | (int)digits[1]) << PyLong_SHIFT) | (int)digits[0])));
                        }
                    }
                    break;
                case -4:
                    if (8 * sizeof(int) - 1 > 3 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 4 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(int, long, -(long) (((((((((unsigned long)digits[3]) << PyLong_SHIFT) | (unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(int) - 1 > 4 * PyLong_SHIFT) {
                            return (int) (((int)-1)*(((((((((int)digits[3]) << PyLong_SHIFT) | (int)digits[2]) << PyLong_SHIFT) | (int)digits[1]) << PyLong_SHIFT) | (int)digits[0])));
                        }
                    }
                    break;
                case 4:
                    if (8 * sizeof(int) > 3 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 4 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(int, unsigned long, (((((((((unsigned long)digits[3]) << PyLong_SHIFT) | (unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(int) - 1 > 4 * PyLong_SHIFT) {
                            return (int) ((((((((((int)digits[3]) << PyLong_SHIFT) | (int)digits[2]) << PyLong_SHIFT) | (int)digits[1]) << PyLong_SHIFT) | (int)digits[0])));
                        }
                    }
                    break;
            }
#endif
            if (sizeof(int) <= sizeof(long)) {
                __PYX_VERIFY_RETURN_INT_EXC(int, long, PyLong_AsLong(x))
#ifdef HAVE_LONG_LONG
            } else if (sizeof(int) <= sizeof(PY_LONG_LONG)) {
                __PYX_VERIFY_RETURN_INT_EXC(int, PY_LONG_LONG, PyLong_AsLongLong(x))
#endif
            }
        }
        {
#if CYTHON_COMPILING_IN_PYPY && !defined(_PyLong_AsByteArray)
            PyErr_SetString(PyExc_RuntimeError,
                            "_PyLong_AsByteArray() not available in PyPy, cannot convert large numbers");
#else
            int val;
            PyObject *v = __Pyx_PyNumber_IntOrLong(x);
 #if PY_MAJOR_VERSION < 3
            if (likely(v) && !PyLong_Check(v)) {
                PyObject *tmp = v;
                v = PyNumber_Long(tmp);
                Py_DECREF(tmp);
            }
 #endif
            if (likely(v)) {
                int one = 1; int is_little = (int)*(unsigned char *)&one;
                unsigned char *bytes = (unsigned char *)&val;
                int ret = _PyLong_AsByteArray((PyLongObject *)v,
                                              bytes, sizeof(val),
                                              is_little, !is_unsigned);
                Py_DECREF(v);
                if (likely(!ret))
                    return val;
            }
#endif
            return (int) -1;
        }
    } else {
        int val;
        PyObject *tmp = __Pyx_PyNumber_IntOrLong(x);
        if (!tmp) return (int) -1;
        val = __Pyx_PyInt_As_int(tmp);
        Py_DECREF(tmp);
        return val;
    }
raise_overflow:
    PyErr_SetString(PyExc_OverflowError,
        "value too large to convert to int");
    return (int) -1;
raise_neg_overflow:
    PyErr_SetString(PyExc_OverflowError,
        "can't convert negative value to int");
    return (int) -1;
}

/* CIntFromPy */
  static CYTHON_INLINE long __Pyx_PyInt_As_long(PyObject *x) {
    const long neg_one = (long) ((long) 0 - (long) 1), const_zero = (long) 0;
    const int is_unsigned = neg_one > const_zero;
#if PY_MAJOR_VERSION < 3
    if (likely(PyInt_Check(x))) {
        if (sizeof(long) < sizeof(long)) {
            __PYX_VERIFY_RETURN_INT(long, long, PyInt_AS_LONG(x))
        } else {
            long val = PyInt_AS_LONG(x);
            if (is_unsigned && unlikely(val < 0)) {
                goto raise_neg_overflow;
            }
            return (long) val;
        }
    } else
#endif
    if (likely(PyLong_Check(x))) {
        if (is_unsigned) {
#if CYTHON_USE_PYLONG_INTERNALS
            const digit* digits = ((PyLongObject*)x)->ob_digit;
            switch (Py_SIZE(x)) {
                case  0: return (long) 0;
                case  1: __PYX_VERIFY_RETURN_INT(long, digit, digits[0])
                case 2:
                    if (8 * sizeof(long) > 1 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 2 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(long, unsigned long, (((((unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(long) >= 2 * PyLong_SHIFT) {
                            return (long) (((((long)digits[1]) << PyLong_SHIFT) | (long)digits[0]));
                        }
                    }
                    break;
                case 3:
                    if (8 * sizeof(long) > 2 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 3 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(long, unsigned long, (((((((unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(long) >= 3 * PyLong_SHIFT) {
                            return (long) (((((((long)digits[2]) << PyLong_SHIFT) | (long)digits[1]) << PyLong_SHIFT) | (long)digits[0]));
                        }
                    }
                    break;
                case 4:
                    if (8 * sizeof(long) > 3 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 4 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(long, unsigned long, (((((((((unsigned long)digits[3]) << PyLong_SHIFT) | (unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(long) >= 4 * PyLong_SHIFT) {
                            return (long) (((((((((long)digits[3]) << PyLong_SHIFT) | (long)digits[2]) << PyLong_SHIFT) | (long)digits[1]) << PyLong_SHIFT) | (long)digits[0]));
                        }
                    }
                    break;
            }
#endif
#if CYTHON_COMPILING_IN_CPYTHON
            if (unlikely(Py_SIZE(x) < 0)) {
                goto raise_neg_overflow;
            }
#else
            {
                int result = PyObject_RichCompareBool(x, Py_False, Py_LT);
                if (unlikely(result < 0))
                    return (long) -1;
                if (unlikely(result == 1))
                    goto raise_neg_overflow;
            }
#endif
            if (sizeof(long) <= sizeof(unsigned long)) {
                __PYX_VERIFY_RETURN_INT_EXC(long, unsigned long, PyLong_AsUnsignedLong(x))
#ifdef HAVE_LONG_LONG
            } else if (sizeof(long) <= sizeof(unsigned PY_LONG_LONG)) {
                __PYX_VERIFY_RETURN_INT_EXC(long, unsigned PY_LONG_LONG, PyLong_AsUnsignedLongLong(x))
#endif
            }
        } else {
#if CYTHON_USE_PYLONG_INTERNALS
            const digit* digits = ((PyLongObject*)x)->ob_digit;
            switch (Py_SIZE(x)) {
                case  0: return (long) 0;
                case -1: __PYX_VERIFY_RETURN_INT(long, sdigit, (sdigit) (-(sdigit)digits[0]))
                case  1: __PYX_VERIFY_RETURN_INT(long,  digit, +digits[0])
                case -2:
                    if (8 * sizeof(long) - 1 > 1 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 2 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(long, long, -(long) (((((unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(long) - 1 > 2 * PyLong_SHIFT) {
                            return (long) (((long)-1)*(((((long)digits[1]) << PyLong_SHIFT) | (long)digits[0])));
                        }
                    }
                    break;
                case 2:
                    if (8 * sizeof(long) > 1 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 2 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(long, unsigned long, (((((unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(long) - 1 > 2 * PyLong_SHIFT) {
                            return (long) ((((((long)digits[1]) << PyLong_SHIFT) | (long)digits[0])));
                        }
                    }
                    break;
                case -3:
                    if (8 * sizeof(long) - 1 > 2 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 3 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(long, long, -(long) (((((((unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(long) - 1 > 3 * PyLong_SHIFT) {
                            return (long) (((long)-1)*(((((((long)digits[2]) << PyLong_SHIFT) | (long)digits[1]) << PyLong_SHIFT) | (long)digits[0])));
                        }
                    }
                    break;
                case 3:
                    if (8 * sizeof(long) > 2 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 3 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(long, unsigned long, (((((((unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(long) - 1 > 3 * PyLong_SHIFT) {
                            return (long) ((((((((long)digits[2]) << PyLong_SHIFT) | (long)digits[1]) << PyLong_SHIFT) | (long)digits[0])));
                        }
                    }
                    break;
                case -4:
                    if (8 * sizeof(long) - 1 > 3 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 4 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(long, long, -(long) (((((((((unsigned long)digits[3]) << PyLong_SHIFT) | (unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(long) - 1 > 4 * PyLong_SHIFT) {
                            return (long) (((long)-1)*(((((((((long)digits[3]) << PyLong_SHIFT) | (long)digits[2]) << PyLong_SHIFT) | (long)digits[1]) << PyLong_SHIFT) | (long)digits[0])));
                        }
                    }
                    break;
                case 4:
                    if (8 * sizeof(long) > 3 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 4 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(long, unsigned long, (((((((((unsigned long)digits[3]) << PyLong_SHIFT) | (unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(long) - 1 > 4 * PyLong_SHIFT) {
                            return (long) ((((((((((long)digits[3]) << PyLong_SHIFT) | (long)digits[2]) << PyLong_SHIFT) | (long)digits[1]) << PyLong_SHIFT) | (long)digits[0])));
                        }
                    }
                    break;
            }
#endif
            if (sizeof(long) <= sizeof(long)) {
                __PYX_VERIFY_RETURN_INT_EXC(long, long, PyLong_AsLong(x))
#ifdef HAVE_LONG_LONG
            } else if (sizeof(long) <= sizeof(PY_LONG_LONG)) {
                __PYX_VERIFY_RETURN_INT_EXC(long, PY_LONG_LONG, PyLong_AsLongLong(x))
#endif
            }
        }
        {
#if CYTHON_COMPILING_IN_PYPY && !defined(_PyLong_AsByteArray)
            PyErr_SetString(PyExc_RuntimeError,
                            "_PyLong_AsByteArray() not available in PyPy, cannot convert large numbers");
#else
            long val;
            PyObject *v = __Pyx_PyNumber_IntOrLong(x);
 #if PY_MAJOR_VERSION < 3
            if (likely(v) && !PyLong_Check(v)) {
                PyObject *tmp = v;
                v = PyNumber_Long(tmp);
                Py_DECREF(tmp);
            }
 #endif
            if (likely(v)) {
                int one = 1; int is_little = (int)*(unsigned char *)&one;
                unsigned char *bytes = (unsigned char *)&val;
                int ret = _PyLong_AsByteArray((PyLongObject *)v,
                                              bytes, sizeof(val),
                                              is_little, !is_unsigned);
                Py_DECREF(v);
                if (likely(!ret))
                    return val;
            }
#endif
            return (long) -1;
        }
    } else {
        long val;
        PyObject *tmp = __Pyx_PyNumber_IntOrLong(x);
        if (!tmp) return (long) -1;
        val = __Pyx_PyInt_As_long(tmp);
        Py_DECREF(tmp);
        return val;
    }
raise_overflow:
    PyErr_SetString(PyExc_OverflowError,
        "value too large to convert to long");
    return (long) -1;
raise_neg_overflow:
    PyErr_SetString(PyExc_OverflowError,
        "can't convert negative value to long");
    return (long) -1;
}

/* CIntFromPy */
  static CYTHON_INLINE size_t __Pyx_PyInt_As_size_t(PyObject *x) {
    const size_t neg_one = (size_t) ((size_t) 0 - (size_t) 1), const_zero = (size_t) 0;
    const int is_unsigned = neg_one > const_zero;
#if PY_MAJOR_VERSION < 3
    if (likely(PyInt_Check(x))) {
        if (sizeof(size_t) < sizeof(long)) {
            __PYX_VERIFY_RETURN_INT(size_t, long, PyInt_AS_LONG(x))
        } else {
            long val = PyInt_AS_LONG(x);
            if (is_unsigned && unlikely(val < 0)) {
                goto raise_neg_overflow;
            }
            return (size_t) val;
        }
    } else
#endif
    if (likely(PyLong_Check(x))) {
        if (is_unsigned) {
#if CYTHON_USE_PYLONG_INTERNALS
            const digit* digits = ((PyLongObject*)x)->ob_digit;
            switch (Py_SIZE(x)) {
                case  0: return (size_t) 0;
                case  1: __PYX_VERIFY_RETURN_INT(size_t, digit, digits[0])
                case 2:
                    if (8 * sizeof(size_t) > 1 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 2 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(size_t, unsigned long, (((((unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(size_t) >= 2 * PyLong_SHIFT) {
                            return (size_t) (((((size_t)digits[1]) << PyLong_SHIFT) | (size_t)digits[0]));
                        }
                    }
                    break;
                case 3:
                    if (8 * sizeof(size_t) > 2 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 3 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(size_t, unsigned long, (((((((unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(size_t) >= 3 * PyLong_SHIFT) {
                            return (size_t) (((((((size_t)digits[2]) << PyLong_SHIFT) | (size_t)digits[1]) << PyLong_SHIFT) | (size_t)digits[0]));
                        }
                    }
                    break;
                case 4:
                    if (8 * sizeof(size_t) > 3 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 4 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(size_t, unsigned long, (((((((((unsigned long)digits[3]) << PyLong_SHIFT) | (unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(size_t) >= 4 * PyLong_SHIFT) {
                            return (size_t) (((((((((size_t)digits[3]) << PyLong_SHIFT) | (size_t)digits[2]) << PyLong_SHIFT) | (size_t)digits[1]) << PyLong_SHIFT) | (size_t)digits[0]));
                        }
                    }
                    break;
            }
#endif
#if CYTHON_COMPILING_IN_CPYTHON
            if (unlikely(Py_SIZE(x) < 0)) {
                goto raise_neg_overflow;
            }
#else
            {
                int result = PyObject_RichCompareBool(x, Py_False, Py_LT);
                if (unlikely(result < 0))
                    return (size_t) -1;
                if (unlikely(result == 1))
                    goto raise_neg_overflow;
            }
#endif
            if (sizeof(size_t) <= sizeof(unsigned long)) {
                __PYX_VERIFY_RETURN_INT_EXC(size_t, unsigned long, PyLong_AsUnsignedLong(x))
#ifdef HAVE_LONG_LONG
            } else if (sizeof(size_t) <= sizeof(unsigned PY_LONG_LONG)) {
                __PYX_VERIFY_RETURN_INT_EXC(size_t, unsigned PY_LONG_LONG, PyLong_AsUnsignedLongLong(x))
#endif
            }
        } else {
#if CYTHON_USE_PYLONG_INTERNALS
            const digit* digits = ((PyLongObject*)x)->ob_digit;
            switch (Py_SIZE(x)) {
                case  0: return (size_t) 0;
                case -1: __PYX_VERIFY_RETURN_INT(size_t, sdigit, (sdigit) (-(sdigit)digits[0]))
                case  1: __PYX_VERIFY_RETURN_INT(size_t,  digit, +digits[0])
                case -2:
                    if (8 * sizeof(size_t) - 1 > 1 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 2 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(size_t, long, -(long) (((((unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(size_t) - 1 > 2 * PyLong_SHIFT) {
                            return (size_t) (((size_t)-1)*(((((size_t)digits[1]) << PyLong_SHIFT) | (size_t)digits[0])));
                        }
                    }
                    break;
                case 2:
                    if (8 * sizeof(size_t) > 1 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 2 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(size_t, unsigned long, (((((unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(size_t) - 1 > 2 * PyLong_SHIFT) {
                            return (size_t) ((((((size_t)digits[1]) << PyLong_SHIFT) | (size_t)digits[0])));
                        }
                    }
                    break;
                case -3:
                    if (8 * sizeof(size_t) - 1 > 2 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 3 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(size_t, long, -(long) (((((((unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(size_t) - 1 > 3 * PyLong_SHIFT) {
                            return (size_t) (((size_t)-1)*(((((((size_t)digits[2]) << PyLong_SHIFT) | (size_t)digits[1]) << PyLong_SHIFT) | (size_t)digits[0])));
                        }
                    }
                    break;
                case 3:
                    if (8 * sizeof(size_t) > 2 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 3 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(size_t, unsigned long, (((((((unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(size_t) - 1 > 3 * PyLong_SHIFT) {
                            return (size_t) ((((((((size_t)digits[2]) << PyLong_SHIFT) | (size_t)digits[1]) << PyLong_SHIFT) | (size_t)digits[0])));
                        }
                    }
                    break;
                case -4:
                    if (8 * sizeof(size_t) - 1 > 3 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 4 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(size_t, long, -(long) (((((((((unsigned long)digits[3]) << PyLong_SHIFT) | (unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(size_t) - 1 > 4 * PyLong_SHIFT) {
                            return (size_t) (((size_t)-1)*(((((((((size_t)digits[3]) << PyLong_SHIFT) | (size_t)digits[2]) << PyLong_SHIFT) | (size_t)digits[1]) << PyLong_SHIFT) | (size_t)digits[0])));
                        }
                    }
                    break;
                case 4:
                    if (8 * sizeof(size_t) > 3 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 4 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(size_t, unsigned long, (((((((((unsigned long)digits[3]) << PyLong_SHIFT) | (unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(size_t) - 1 > 4 * PyLong_SHIFT) {
                            return (size_t) ((((((((((size_t)digits[3]) << PyLong_SHIFT) | (size_t)digits[2]) << PyLong_SHIFT) | (size_t)digits[1]) << PyLong_SHIFT) | (size_t)digits[0])));
                        }
                    }
                    break;
            }
#endif
            if (sizeof(size_t) <= sizeof(long)) {
                __PYX_VERIFY_RETURN_INT_EXC(size_t, long, PyLong_AsLong(x))
#ifdef HAVE_LONG_LONG
            } else if (sizeof(size_t) <= sizeof(PY_LONG_LONG)) {
                __PYX_VERIFY_RETURN_INT_EXC(size_t, PY_LONG_LONG, PyLong_AsLongLong(x))
#endif
            }
        }
        {
#if CYTHON_COMPILING_IN_PYPY && !defined(_PyLong_AsByteArray)
            PyErr_SetString(PyExc_RuntimeError,
                            "_PyLong_AsByteArray() not available in PyPy, cannot convert large numbers");
#else
            size_t val;
            PyObject *v = __Pyx_PyNumber_IntOrLong(x);
 #if PY_MAJOR_VERSION < 3
            if (likely(v) && !PyLong_Check(v)) {
                PyObject *tmp = v;
                v = PyNumber_Long(tmp);
                Py_DECREF(tmp);
            }
 #endif
            if (likely(v)) {
                int one = 1; int is_little = (int)*(unsigned char *)&one;
                unsigned char *bytes = (unsigned char *)&val;
                int ret = _PyLong_AsByteArray((PyLongObject *)v,
                                              bytes, sizeof(val),
                                              is_little, !is_unsigned);
                Py_DECREF(v);
                if (likely(!ret))
                    return val;
            }
#endif
            return (size_t) -1;
        }
    } else {
        size_t val;
        PyObject *tmp = __Pyx_PyNumber_IntOrLong(x);
        if (!tmp) return (size_t) -1;
        val = __Pyx_PyInt_As_size_t(tmp);
        Py_DECREF(tmp);
        return val;
    }
raise_overflow:
    PyErr_SetString(PyExc_OverflowError,
        "value too large to convert to size_t");
    return (size_t) -1;
raise_neg_overflow:
    PyErr_SetString(PyExc_OverflowError,
        "can't convert negative value to size_t");
    return (size_t) -1;
}

/* ImportNumPyArray */
  static PyObject* __Pyx__ImportNumPyArray(void) {
    PyObject *numpy_module, *ndarray_object = NULL;
    numpy_module = __Pyx_Import(__pyx_n_s_numpy, NULL, 0);
    if (likely(numpy_module)) {
        ndarray_object = PyObject_GetAttrString(numpy_module, "ndarray");
        Py_DECREF(numpy_module);
    }
    if (unlikely(!ndarray_object)) {
        PyErr_Clear();
    }
    if (unlikely(!ndarray_object || !PyObject_TypeCheck(ndarray_object, &PyType_Type))) {
        Py_XDECREF(ndarray_object);
        Py_INCREF(Py_None);
        ndarray_object = Py_None;
    }
    return ndarray_object;
}
static CYTHON_INLINE PyObject* __Pyx_ImportNumPyArrayTypeIfAvailable(void) {
    if (unlikely(!__pyx_numpy_ndarray)) {
        __pyx_numpy_ndarray = __Pyx__ImportNumPyArray();
    }
    Py_INCREF(__pyx_numpy_ndarray);
    return __pyx_numpy_ndarray;
}

/* CIntToPy */
  static CYTHON_INLINE PyObject* __Pyx_PyInt_From_enum____pyx_t_12ms_deisotope_2_c_18similarity_methods_SimilarityMetrics(enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_SimilarityMetrics value) {
    const enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_SimilarityMetrics neg_one = (enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_SimilarityMetrics) ((enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_SimilarityMetrics) 0 - (enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_SimilarityMetrics) 1), const_zero = (enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_SimilarityMetrics) 0;
    const int is_unsigned = neg_one > const_zero;
    if (is_unsigned) {
        if (sizeof(enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_SimilarityMetrics) < sizeof(long)) {
            return PyInt_FromLong((long) value);
        } else if (sizeof(enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_SimilarityMetrics) <= sizeof(unsigned long)) {
            return PyLong_FromUnsignedLong((unsigned long) value);
#ifdef HAVE_LONG_LONG
        } else if (sizeof(enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_SimilarityMetrics) <= sizeof(unsigned PY_LONG_LONG)) {
            return PyLong_FromUnsignedLongLong((unsigned PY_LONG_LONG) value);
#endif
        }
    } else {
        if (sizeof(enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_SimilarityMetrics) <= sizeof(long)) {
            return PyInt_FromLong((long) value);
#ifdef HAVE_LONG_LONG
        } else if (sizeof(enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_SimilarityMetrics) <= sizeof(PY_LONG_LONG)) {
            return PyLong_FromLongLong((PY_LONG_LONG) value);
#endif
        }
    }
    {
        int one = 1; int little = (int)*(unsigned char *)&one;
        unsigned char *bytes = (unsigned char *)&value;
        return _PyLong_FromByteArray(bytes, sizeof(enum __pyx_t_12ms_deisotope_2_c_18similarity_methods_SimilarityMetrics),
                                     little, !is_unsigned);
    }
}

/* FastTypeChecks */
  #if CYTHON_COMPILING_IN_CPYTHON
static int __Pyx_InBases(PyTypeObject *a, PyTypeObject *b) {
    while (a) {
        a = a->tp_base;
        if (a == b)
            return 1;
    }
    return b == &PyBaseObject_Type;
}
static CYTHON_INLINE int __Pyx_IsSubtype(PyTypeObject *a, PyTypeObject *b) {
    PyObject *mro;
    if (a == b) return 1;
    mro = a->tp_mro;
    if (likely(mro)) {
        Py_ssize_t i, n;
        n = PyTuple_GET_SIZE(mro);
        for (i = 0; i < n; i++) {
            if (PyTuple_GET_ITEM(mro, i) == (PyObject *)b)
                return 1;
        }
        return 0;
    }
    return __Pyx_InBases(a, b);
}
#if PY_MAJOR_VERSION == 2
static int __Pyx_inner_PyErr_GivenExceptionMatches2(PyObject *err, PyObject* exc_type1, PyObject* exc_type2) {
    PyObject *exception, *value, *tb;
    int res;
    __Pyx_PyThreadState_declare
    __Pyx_PyThreadState_assign
    __Pyx_ErrFetch(&exception, &value, &tb);
    res = exc_type1 ? PyObject_IsSubclass(err, exc_type1) : 0;
    if (unlikely(res == -1)) {
        PyErr_WriteUnraisable(err);
        res = 0;
    }
    if (!res) {
        res = PyObject_IsSubclass(err, exc_type2);
        if (unlikely(res == -1)) {
            PyErr_WriteUnraisable(err);
            res = 0;
        }
    }
    __Pyx_ErrRestore(exception, value, tb);
    return res;
}
#else
static CYTHON_INLINE int __Pyx_inner_PyErr_GivenExceptionMatches2(PyObject *err, PyObject* exc_type1, PyObject *exc_type2) {
    int res = exc_type1 ? __Pyx_IsSubtype((PyTypeObject*)err, (PyTypeObject*)exc_type1) : 0;
    if (!res) {
        res = __Pyx_IsSubtype((PyTypeObject*)err, (PyTypeObject*)exc_type2);
    }
    return res;
}
#endif
static int __Pyx_PyErr_GivenExceptionMatchesTuple(PyObject *exc_type, PyObject *tuple) {
    Py_ssize_t i, n;
    assert(PyExceptionClass_Check(exc_type));
    n = PyTuple_GET_SIZE(tuple);
#if PY_MAJOR_VERSION >= 3
    for (i=0; i<n; i++) {
        if (exc_type == PyTuple_GET_ITEM(tuple, i)) return 1;
    }
#endif
    for (i=0; i<n; i++) {
        PyObject *t = PyTuple_GET_ITEM(tuple, i);
        #if PY_MAJOR_VERSION < 3
        if (likely(exc_type == t)) return 1;
        #endif
        if (likely(PyExceptionClass_Check(t))) {
            if (__Pyx_inner_PyErr_GivenExceptionMatches2(exc_type, NULL, t)) return 1;
        } else {
        }
    }
    return 0;
}
static CYTHON_INLINE int __Pyx_PyErr_GivenExceptionMatches(PyObject *err, PyObject* exc_type) {
    if (likely(err == exc_type)) return 1;
    if (likely(PyExceptionClass_Check(err))) {
        if (likely(PyExceptionClass_Check(exc_type))) {
            return __Pyx_inner_PyErr_GivenExceptionMatches2(err, NULL, exc_type);
        } else if (likely(PyTuple_Check(exc_type))) {
            return __Pyx_PyErr_GivenExceptionMatchesTuple(err, exc_type);
        } else {
        }
    }
    return PyErr_GivenExceptionMatches(err, exc_type);
}
static CYTHON_INLINE int __Pyx_PyErr_GivenExceptionMatches2(PyObject *err, PyObject *exc_type1, PyObject *exc_type2) {
    assert(PyExceptionClass_Check(exc_type1));
    assert(PyExceptionClass_Check(exc_type2));
    if (likely(err == exc_type1 || err == exc_type2)) return 1;
    if (likely(PyExceptionClass_Check(err))) {
        return __Pyx_inner_PyErr_GivenExceptionMatches2(err, exc_type1, exc_type2);
    }
    return (PyErr_GivenExceptionMatches(err, exc_type1) || PyErr_GivenExceptionMatches(err, exc_type2));
}
#endif

/* CheckBinaryVersion */
  static int __Pyx_check_binary_version(void) {
    char ctversion[4], rtversion[4];
    PyOS_snprintf(ctversion, 4, "%d.%d", PY_MAJOR_VERSION, PY_MINOR_VERSION);
    PyOS_snprintf(rtversion, 4, "%s", Py_GetVersion());
    if (ctversion[0] != rtversion[0] || ctversion[2] != rtversion[2]) {
        char message[200];
        PyOS_snprintf(message, sizeof(message),
                      "compiletime version %s of module '%.100s' "
                      "does not match runtime version %s",
                      ctversion, __Pyx_MODULE_NAME, rtversion);
        return PyErr_WarnEx(NULL, message, 1);
    }
    return 0;
}

/* VoidPtrImport */
  #ifndef __PYX_HAVE_RT_ImportVoidPtr
#define __PYX_HAVE_RT_ImportVoidPtr
static int __Pyx_ImportVoidPtr(PyObject *module, const char *name, void **p, const char *sig) {
    PyObject *d = 0;
    PyObject *cobj = 0;
    d = PyObject_GetAttrString(module, (char *)"__pyx_capi__");
    if (!d)
        goto bad;
    cobj = PyDict_GetItemString(d, name);
    if (!cobj) {
        PyErr_Format(PyExc_ImportError,
            "%.200s does not export expected C variable %.200s",
                PyModule_GetName(module), name);
        goto bad;
    }
#if PY_VERSION_HEX >= 0x02070000
    if (!PyCapsule_IsValid(cobj, sig)) {
        PyErr_Format(PyExc_TypeError,
            "C variable %.200s.%.200s has wrong signature (expected %.500s, got %.500s)",
             PyModule_GetName(module), name, sig, PyCapsule_GetName(cobj));
        goto bad;
    }
    *p = PyCapsule_GetPointer(cobj, sig);
#else
    {const char *desc, *s1, *s2;
    desc = (const char *)PyCObject_GetDesc(cobj);
    if (!desc)
        goto bad;
    s1 = desc; s2 = sig;
    while (*s1 != '\0' && *s1 == *s2) { s1++; s2++; }
    if (*s1 != *s2) {
        PyErr_Format(PyExc_TypeError,
            "C variable %.200s.%.200s has wrong signature (expected %.500s, got %.500s)",
             PyModule_GetName(module), name, sig, desc);
        goto bad;
    }
    *p = PyCObject_AsVoidPtr(cobj);}
#endif
    if (!(*p))
        goto bad;
    Py_DECREF(d);
    return 0;
bad:
    Py_XDECREF(d);
    return -1;
}
#endif

/* InitStrings */
  static int __Pyx_InitStrings(__Pyx_StringTabEntry *t) {
    while (t->p) {
        #if PY_MAJOR_VERSION < 3
        if (t->is_unicode) {
            *t->p = PyUnicode_DecodeUTF8(t->s, t->n - 1, NULL);
        } else if (t->intern) {
            *t->p = PyString_InternFromString(t->s);
        } else {
            *t->p = PyString_FromStringAndSize(t->s, t->n - 1);
        }
        #else
        if (t->is_unicode | t->is_str) {
            if (t->intern) {
                *t->p = PyUnicode_InternFromString(t->s);
            } else if (t->encoding) {
                *t->p = PyUnicode_Decode(t->s, t->n - 1, t->encoding, NULL);
            } else {
                *t->p = PyUnicode_FromStringAndSize(t->s, t->n - 1);
            }
        } else {
            *t->p = PyBytes_FromStringAndSize(t->s, t->n - 1);
        }
        #endif
        if (!*t->p)
            return -1;
        if (PyObject_Hash(*t->p) == -1)
            return -1;
        ++t;
    }
    return 0;
}

static CYTHON_INLINE PyObject* __Pyx_PyUnicode_FromString(const char* c_str) {
    return __Pyx_PyUnicode_FromStringAndSize(c_str, (Py_ssize_t)strlen(c_str));
}
static CYTHON_INLINE const char* __Pyx_PyObject_AsString(PyObject* o) {
    Py_ssize_t ignore;
    return __Pyx_PyObject_AsStringAndSize(o, &ignore);
}
#if __PYX_DEFAULT_STRING_ENCODING_IS_ASCII || __PYX_DEFAULT_STRING_ENCODING_IS_DEFAULT
#if !CYTHON_PEP393_ENABLED
static const char* __Pyx_PyUnicode_AsStringAndSize(PyObject* o, Py_ssize_t *length) {
    char* defenc_c;
    PyObject* defenc = _PyUnicode_AsDefaultEncodedString(o, NULL);
    if (!defenc) return NULL;
    defenc_c = PyBytes_AS_STRING(defenc);
#if __PYX_DEFAULT_STRING_ENCODING_IS_ASCII
    {
        char* end = defenc_c + PyBytes_GET_SIZE(defenc);
        char* c;
        for (c = defenc_c; c < end; c++) {
            if ((unsigned char) (*c) >= 128) {
                PyUnicode_AsASCIIString(o);
                return NULL;
            }
        }
    }
#endif
    *length = PyBytes_GET_SIZE(defenc);
    return defenc_c;
}
#else
static CYTHON_INLINE const char* __Pyx_PyUnicode_AsStringAndSize(PyObject* o, Py_ssize_t *length) {
    if (unlikely(__Pyx_PyUnicode_READY(o) == -1)) return NULL;
#if __PYX_DEFAULT_STRING_ENCODING_IS_ASCII
    if (likely(PyUnicode_IS_ASCII(o))) {
        *length = PyUnicode_GET_LENGTH(o);
        return PyUnicode_AsUTF8(o);
    } else {
        PyUnicode_AsASCIIString(o);
        return NULL;
    }
#else
    return PyUnicode_AsUTF8AndSize(o, length);
#endif
}
#endif
#endif
static CYTHON_INLINE const char* __Pyx_PyObject_AsStringAndSize(PyObject* o, Py_ssize_t *length) {
#if __PYX_DEFAULT_STRING_ENCODING_IS_ASCII || __PYX_DEFAULT_STRING_ENCODING_IS_DEFAULT
    if (
#if PY_MAJOR_VERSION < 3 && __PYX_DEFAULT_STRING_ENCODING_IS_ASCII
            __Pyx_sys_getdefaultencoding_not_ascii &&
#endif
            PyUnicode_Check(o)) {
        return __Pyx_PyUnicode_AsStringAndSize(o, length);
    } else
#endif
#if (!CYTHON_COMPILING_IN_PYPY) || (defined(PyByteArray_AS_STRING) && defined(PyByteArray_GET_SIZE))
    if (PyByteArray_Check(o)) {
        *length = PyByteArray_GET_SIZE(o);
        return PyByteArray_AS_STRING(o);
    } else
#endif
    {
        char* result;
        int r = PyBytes_AsStringAndSize(o, &result, length);
        if (unlikely(r < 0)) {
            return NULL;
        } else {
            return result;
        }
    }
}
static CYTHON_INLINE int __Pyx_PyObject_IsTrue(PyObject* x) {
   int is_true = x == Py_True;
   if (is_true | (x == Py_False) | (x == Py_None)) return is_true;
   else return PyObject_IsTrue(x);
}
static CYTHON_INLINE int __Pyx_PyObject_IsTrueAndDecref(PyObject* x) {
    int retval;
    if (unlikely(!x)) return -1;
    retval = __Pyx_PyObject_IsTrue(x);
    Py_DECREF(x);
    return retval;
}
static PyObject* __Pyx_PyNumber_IntOrLongWrongResultType(PyObject* result, const char* type_name) {
#if PY_MAJOR_VERSION >= 3
    if (PyLong_Check(result)) {
        if (PyErr_WarnFormat(PyExc_DeprecationWarning, 1,
                "__int__ returned non-int (type %.200s).  "
                "The ability to return an instance of a strict subclass of int "
                "is deprecated, and may be removed in a future version of Python.",
                Py_TYPE(result)->tp_name)) {
            Py_DECREF(result);
            return NULL;
        }
        return result;
    }
#endif
    PyErr_Format(PyExc_TypeError,
                 "__%.4s__ returned non-%.4s (type %.200s)",
                 type_name, type_name, Py_TYPE(result)->tp_name);
    Py_DECREF(result);
    return NULL;
}
static CYTHON_INLINE PyObject* __Pyx_PyNumber_IntOrLong(PyObject* x) {
#if CYTHON_USE_TYPE_SLOTS
  PyNumberMethods *m;
#endif
  const char *name = NULL;
  PyObject *res = NULL;
#if PY_MAJOR_VERSION < 3
  if (likely(PyInt_Check(x) || PyLong_Check(x)))
#else
  if (likely(PyLong_Check(x)))
#endif
    return __Pyx_NewRef(x);
#if CYTHON_USE_TYPE_SLOTS
  m = Py_TYPE(x)->tp_as_number;
  #if PY_MAJOR_VERSION < 3
  if (m && m->nb_int) {
    name = "int";
    res = m->nb_int(x);
  }
  else if (m && m->nb_long) {
    name = "long";
    res = m->nb_long(x);
  }
  #else
  if (likely(m && m->nb_int)) {
    name = "int";
    res = m->nb_int(x);
  }
  #endif
#else
  if (!PyBytes_CheckExact(x) && !PyUnicode_CheckExact(x)) {
    res = PyNumber_Int(x);
  }
#endif
  if (likely(res)) {
#if PY_MAJOR_VERSION < 3
    if (unlikely(!PyInt_Check(res) && !PyLong_Check(res))) {
#else
    if (unlikely(!PyLong_CheckExact(res))) {
#endif
        return __Pyx_PyNumber_IntOrLongWrongResultType(res, name);
    }
  }
  else if (!PyErr_Occurred()) {
    PyErr_SetString(PyExc_TypeError,
                    "an integer is required");
  }
  return res;
}
static CYTHON_INLINE Py_ssize_t __Pyx_PyIndex_AsSsize_t(PyObject* b) {
  Py_ssize_t ival;
  PyObject *x;
#if PY_MAJOR_VERSION < 3
  if (likely(PyInt_CheckExact(b))) {
    if (sizeof(Py_ssize_t) >= sizeof(long))
        return PyInt_AS_LONG(b);
    else
        return PyInt_AsSsize_t(b);
  }
#endif
  if (likely(PyLong_CheckExact(b))) {
    #if CYTHON_USE_PYLONG_INTERNALS
    const digit* digits = ((PyLongObject*)b)->ob_digit;
    const Py_ssize_t size = Py_SIZE(b);
    if (likely(__Pyx_sst_abs(size) <= 1)) {
        ival = likely(size) ? digits[0] : 0;
        if (size == -1) ival = -ival;
        return ival;
    } else {
      switch (size) {
         case 2:
           if (8 * sizeof(Py_ssize_t) > 2 * PyLong_SHIFT) {
             return (Py_ssize_t) (((((size_t)digits[1]) << PyLong_SHIFT) | (size_t)digits[0]));
           }
           break;
         case -2:
           if (8 * sizeof(Py_ssize_t) > 2 * PyLong_SHIFT) {
             return -(Py_ssize_t) (((((size_t)digits[1]) << PyLong_SHIFT) | (size_t)digits[0]));
           }
           break;
         case 3:
           if (8 * sizeof(Py_ssize_t) > 3 * PyLong_SHIFT) {
             return (Py_ssize_t) (((((((size_t)digits[2]) << PyLong_SHIFT) | (size_t)digits[1]) << PyLong_SHIFT) | (size_t)digits[0]));
           }
           break;
         case -3:
           if (8 * sizeof(Py_ssize_t) > 3 * PyLong_SHIFT) {
             return -(Py_ssize_t) (((((((size_t)digits[2]) << PyLong_SHIFT) | (size_t)digits[1]) << PyLong_SHIFT) | (size_t)digits[0]));
           }
           break;
         case 4:
           if (8 * sizeof(Py_ssize_t) > 4 * PyLong_SHIFT) {
             return (Py_ssize_t) (((((((((size_t)digits[3]) << PyLong_SHIFT) | (size_t)digits[2]) << PyLong_SHIFT) | (size_t)digits[1]) << PyLong_SHIFT) | (size_t)digits[0]));
           }
           break;
         case -4:
           if (8 * sizeof(Py_ssize_t) > 4 * PyLong_SHIFT) {
             return -(Py_ssize_t) (((((((((size_t)digits[3]) << PyLong_SHIFT) | (size_t)digits[2]) << PyLong_SHIFT) | (size_t)digits[1]) << PyLong_SHIFT) | (size_t)digits[0]));
           }
           break;
      }
    }
    #endif
    return PyLong_AsSsize_t(b);
  }
  x = PyNumber_Index(b);
  if (!x) return -1;
  ival = PyInt_AsSsize_t(x);
  Py_DECREF(x);
  return ival;
}
static CYTHON_INLINE PyObject * __Pyx_PyBool_FromLong(long b) {
  return b ? __Pyx_NewRef(Py_True) : __Pyx_NewRef(Py_False);
}
static CYTHON_INLINE PyObject * __Pyx_PyInt_FromSize_t(size_t ival) {
    return PyInt_FromSize_t(ival);
}


#endif /* Py_PYTHON_H */
