/* Generated by Cython 0.26.1 */

/* BEGIN: Cython Metadata
{
    "distutils": {
        "depends": [
            "src/tx.h"
        ],
        "extra_compile_args": [
            "-std=c++11",
            "-stdlib=libc++"
        ],
        "include_dirs": [
            "src/"
        ],
        "language": "c++",
        "name": "denovonear.transcript",
        "sources": [
            "denovonear/transcript.pyx",
            "src/tx.cpp"
        ]
    },
    "module_name": "denovonear.transcript"
}
END: Cython Metadata */

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#define __PYX_HAVE__denovonear__transcript
#define __PYX_HAVE_API__denovonear__transcript
#include <vector>
#include "ios"
#include "new"
#include "stdexcept"
#include "typeinfo"
#include <string.h>
#include <string>
#include "tx.h"
#ifdef _OPENMP
#include <omp.h>
#endif /* _OPENMP */

#ifdef PYREX_WITHOUT_ASSERTIONS
#define CYTHON_WITHOUT_ASSERTIONS
#endif

typedef struct {PyObject **p; const char *s; const Py_ssize_t n; const char* encoding;
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#define __PYX_DEFAULT_STRING_ENCODING_IS_ASCII 0
#define __PYX_DEFAULT_STRING_ENCODING_IS_DEFAULT 0
#define __PYX_DEFAULT_STRING_ENCODING ""
#define __Pyx_PyObject_FromString __Pyx_PyBytes_FromString
#define __Pyx_PyObject_FromStringAndSize __Pyx_PyBytes_FromStringAndSize
#define __Pyx_uchar_cast(c) ((unsigned char)c)
#define __Pyx_long_cast(x) ((long)x)
#define __Pyx_fits_Py_ssize_t(v, type, is_signed)  (\
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    (sizeof(type) > sizeof(Py_ssize_t) &&\
          likely(v < (type)PY_SSIZE_T_MAX ||\
                 v == (type)PY_SSIZE_T_MAX)  &&\
          (!is_signed || likely(v > (type)PY_SSIZE_T_MIN ||\
                                v == (type)PY_SSIZE_T_MIN)))  ||\
    (sizeof(type) == sizeof(Py_ssize_t) &&\
          (is_signed || likely(v < (type)PY_SSIZE_T_MAX ||\
                               v == (type)PY_SSIZE_T_MAX)))  )
#if defined (__cplusplus) && __cplusplus >= 201103L
    #include <cstdlib>
    #define __Pyx_sst_abs(value) std::abs(value)
#elif SIZEOF_INT >= SIZEOF_SIZE_T
    #define __Pyx_sst_abs(value) abs(value)
#elif SIZEOF_LONG >= SIZEOF_SIZE_T
    #define __Pyx_sst_abs(value) labs(value)
#elif defined (_MSC_VER) && defined (_M_X64)
    #define __Pyx_sst_abs(value) _abs64(value)
#elif defined (__STDC_VERSION__) && __STDC_VERSION__ >= 199901L
    #define __Pyx_sst_abs(value) llabs(value)
#elif defined (__GNUC__)
    #define __Pyx_sst_abs(value) __builtin_llabs(value)
#else
    #define __Pyx_sst_abs(value) ((value<0) ? -value : value)
#endif
static CYTHON_INLINE const char* __Pyx_PyObject_AsString(PyObject*);
static CYTHON_INLINE const char* __Pyx_PyObject_AsStringAndSize(PyObject*, Py_ssize_t* length);
#define __Pyx_PyByteArray_FromString(s) PyByteArray_FromStringAndSize((const char*)s, strlen((const char*)s))
#define __Pyx_PyByteArray_FromStringAndSize(s, l) PyByteArray_FromStringAndSize((const char*)s, l)
#define __Pyx_PyBytes_FromString        PyBytes_FromString
#define __Pyx_PyBytes_FromStringAndSize PyBytes_FromStringAndSize
static CYTHON_INLINE PyObject* __Pyx_PyUnicode_FromString(const char*);
#if PY_MAJOR_VERSION < 3
    #define __Pyx_PyStr_FromString        __Pyx_PyBytes_FromString
    #define __Pyx_PyStr_FromStringAndSize __Pyx_PyBytes_FromStringAndSize
#else
    #define __Pyx_PyStr_FromString        __Pyx_PyUnicode_FromString
    #define __Pyx_PyStr_FromStringAndSize __Pyx_PyUnicode_FromStringAndSize
#endif
#define __Pyx_PyObject_AsWritableString(s)    ((char*) __Pyx_PyObject_AsString(s))
#define __Pyx_PyObject_AsWritableSString(s)    ((signed char*) __Pyx_PyObject_AsString(s))
#define __Pyx_PyObject_AsWritableUString(s)    ((unsigned char*) __Pyx_PyObject_AsString(s))
#define __Pyx_PyObject_AsSString(s)    ((const signed char*) __Pyx_PyObject_AsString(s))
#define __Pyx_PyObject_AsUString(s)    ((const unsigned char*) __Pyx_PyObject_AsString(s))
#define __Pyx_PyObject_FromCString(s)  __Pyx_PyObject_FromString((const char*)s)
#define __Pyx_PyBytes_FromCString(s)   __Pyx_PyBytes_FromString((const char*)s)
#define __Pyx_PyByteArray_FromCString(s)   __Pyx_PyByteArray_FromString((const char*)s)
#define __Pyx_PyStr_FromCString(s)     __Pyx_PyStr_FromString((const char*)s)
#define __Pyx_PyUnicode_FromCString(s) __Pyx_PyUnicode_FromString((const char*)s)
#if PY_MAJOR_VERSION < 3
static CYTHON_INLINE size_t __Pyx_Py_UNICODE_strlen(const Py_UNICODE *u)
{
    const Py_UNICODE *u_end = u;
    while (*u_end++) ;
    return (size_t)(u_end - u - 1);
}
#else
#define __Pyx_Py_UNICODE_strlen Py_UNICODE_strlen
#endif
#define __Pyx_PyUnicode_FromUnicode(u)       PyUnicode_FromUnicode(u, __Pyx_Py_UNICODE_strlen(u))
#define __Pyx_PyUnicode_FromUnicodeAndLength PyUnicode_FromUnicode
#define __Pyx_PyUnicode_AsUnicode            PyUnicode_AsUnicode
#define __Pyx_NewRef(obj) (Py_INCREF(obj), obj)
#define __Pyx_Owned_Py_None(b) __Pyx_NewRef(Py_None)
#define __Pyx_PyBool_FromLong(b) ((b) ? __Pyx_NewRef(Py_True) : __Pyx_NewRef(Py_False))
static CYTHON_INLINE int __Pyx_PyObject_IsTrue(PyObject*);
static CYTHON_INLINE PyObject* __Pyx_PyNumber_IntOrLong(PyObject* x);
static CYTHON_INLINE Py_ssize_t __Pyx_PyIndex_AsSsize_t(PyObject*);
static CYTHON_INLINE PyObject * __Pyx_PyInt_FromSize_t(size_t);
#if CYTHON_ASSUME_SAFE_MACROS
#define __pyx_PyFloat_AsDouble(x) (PyFloat_CheckExact(x) ? PyFloat_AS_DOUBLE(x) : PyFloat_AsDouble(x))
#else
#define __pyx_PyFloat_AsDouble(x) PyFloat_AsDouble(x)
#endif
#define __pyx_PyFloat_AsFloat(x) ((float) __pyx_PyFloat_AsDouble(x))
#if PY_MAJOR_VERSION >= 3
#define __Pyx_PyNumber_Int(x) (PyLong_CheckExact(x) ? __Pyx_NewRef(x) : PyNumber_Long(x))
#else
#define __Pyx_PyNumber_Int(x) (PyInt_CheckExact(x) ? __Pyx_NewRef(x) : PyNumber_Int(x))
#endif
#define __Pyx_PyNumber_Float(x) (PyFloat_CheckExact(x) ? __Pyx_NewRef(x) : PyNumber_Float(x))
#if PY_MAJOR_VERSION < 3 && __PYX_DEFAULT_STRING_ENCODING_IS_ASCII
static int __Pyx_sys_getdefaultencoding_not_ascii;
static int __Pyx_init_sys_getdefaultencoding_params(void) {
    PyObject* sys;
    PyObject* default_encoding = NULL;
    PyObject* ascii_chars_u = NULL;
    PyObject* ascii_chars_b = NULL;
    const char* default_encoding_c;
    sys = PyImport_ImportModule("sys");
    if (!sys) goto bad;
    default_encoding = PyObject_CallMethod(sys, (char*) "getdefaultencoding", NULL);
    Py_DECREF(sys);
    if (!default_encoding) goto bad;
    default_encoding_c = PyBytes_AsString(default_encoding);
    if (!default_encoding_c) goto bad;
    if (strcmp(default_encoding_c, "ascii") == 0) {
        __Pyx_sys_getdefaultencoding_not_ascii = 0;
    } else {
        char ascii_chars[128];
        int c;
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        __Pyx_sys_getdefaultencoding_not_ascii = 1;
        ascii_chars_u = PyUnicode_DecodeASCII(ascii_chars, 128, NULL);
        if (!ascii_chars_u) goto bad;
        ascii_chars_b = PyUnicode_AsEncodedString(ascii_chars_u, default_encoding_c, NULL);
        if (!ascii_chars_b || !PyBytes_Check(ascii_chars_b) || memcmp(ascii_chars, PyBytes_AS_STRING(ascii_chars_b), 128) != 0) {
            PyErr_Format(
                PyExc_ValueError,
                "This module compiled with c_string_encoding=ascii, but default encoding '%.200s' is not a superset of ascii.",
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            goto bad;
        }
        Py_DECREF(ascii_chars_u);
        Py_DECREF(ascii_chars_b);
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    Py_DECREF(default_encoding);
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bad:
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    Py_XDECREF(ascii_chars_u);
    Py_XDECREF(ascii_chars_b);
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}
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#if __PYX_DEFAULT_STRING_ENCODING_IS_DEFAULT && PY_MAJOR_VERSION >= 3
#define __Pyx_PyUnicode_FromStringAndSize(c_str, size) PyUnicode_DecodeUTF8(c_str, size, NULL)
#else
#define __Pyx_PyUnicode_FromStringAndSize(c_str, size) PyUnicode_Decode(c_str, size, __PYX_DEFAULT_STRING_ENCODING, NULL)
#if __PYX_DEFAULT_STRING_ENCODING_IS_DEFAULT
static char* __PYX_DEFAULT_STRING_ENCODING;
static int __Pyx_init_sys_getdefaultencoding_params(void) {
    PyObject* sys;
    PyObject* default_encoding = NULL;
    char* default_encoding_c;
    sys = PyImport_ImportModule("sys");
    if (!sys) goto bad;
    default_encoding = PyObject_CallMethod(sys, (char*) (const char*) "getdefaultencoding", NULL);
    Py_DECREF(sys);
    if (!default_encoding) goto bad;
    default_encoding_c = PyBytes_AsString(default_encoding);
    if (!default_encoding_c) goto bad;
    __PYX_DEFAULT_STRING_ENCODING = (char*) malloc(strlen(default_encoding_c));
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bad:
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/* Test for GCC > 2.95 */
#if defined(__GNUC__)     && (__GNUC__ > 2 || (__GNUC__ == 2 && (__GNUC_MINOR__ > 95)))
  #define likely(x)   __builtin_expect(!!(x), 1)
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#else /* !__GNUC__ or GCC < 2.95 */
  #define likely(x)   (x)
  #define unlikely(x) (x)
#endif /* __GNUC__ */
static CYTHON_INLINE void __Pyx_pretend_to_initialize(void* ptr) { (void)ptr; }

static PyObject *__pyx_m;
static PyObject *__pyx_d;
static PyObject *__pyx_b;
static PyObject *__pyx_cython_runtime;
static PyObject *__pyx_empty_tuple;
static PyObject *__pyx_empty_bytes;
static PyObject *__pyx_empty_unicode;
static int __pyx_lineno;
static int __pyx_clineno = 0;
static const char * __pyx_cfilenm= __FILE__;
static const char *__pyx_filename;


static const char *__pyx_f[] = {
  "denovonear/transcript.pyx",
  "stringsource",
};

/*--- Type declarations ---*/
struct __pyx_obj_10denovonear_10transcript_Transcript;
struct __pyx_obj_10denovonear_10transcript___pyx_scope_struct__insert_region;
struct __pyx_obj_10denovonear_10transcript___pyx_scope_struct_1_genexpr;
struct __pyx_obj_10denovonear_10transcript___pyx_scope_struct_2_genexpr;

/* "denovonear/transcript.pxd":85
 *         int offset
 * 
 * cdef class Transcript:             # <<<<<<<<<<<<<<
 *     cdef Tx *thisptr # hold a C++ instance which we're wrapping
 */
struct __pyx_obj_10denovonear_10transcript_Transcript {
  PyObject_HEAD
  Tx *thisptr;
};


/* "denovonear/transcript.pyx":111
 *             exon['start'] <= x['end'] and exon['end'] >= x['start'] ]
 * 
 *     def insert_region(self, coords, region):             # <<<<<<<<<<<<<<
 *         ''' include a region into a list of regions
 * 
 */
struct __pyx_obj_10denovonear_10transcript___pyx_scope_struct__insert_region {
  PyObject_HEAD
  PyObject *__pyx_v_overlaps;
  PyObject *__pyx_v_region;
};


/* "denovonear/transcript.pyx":123
 *         indices = self.get_overlaps(region, coords)
 *         overlaps = [ coords[i] for i in indices ]
 *         start = min( x['start'] for x in overlaps + [region] )             # <<<<<<<<<<<<<<
 *         end = max( x['end'] for x in overlaps + [region] )
 * 
 */
struct __pyx_obj_10denovonear_10transcript___pyx_scope_struct_1_genexpr {
  PyObject_HEAD
  struct __pyx_obj_10denovonear_10transcript___pyx_scope_struct__insert_region *__pyx_outer_scope;
  PyObject *__pyx_v_x;
  PyObject *__pyx_t_0;
  Py_ssize_t __pyx_t_1;
};


/* "denovonear/transcript.pyx":124
 *         overlaps = [ coords[i] for i in indices ]
 *         start = min( x['start'] for x in overlaps + [region] )
 *         end = max( x['end'] for x in overlaps + [region] )             # <<<<<<<<<<<<<<
 * 
 *         for i in sorted(indices, reverse=True):
 */
struct __pyx_obj_10denovonear_10transcript___pyx_scope_struct_2_genexpr {
  PyObject_HEAD
  struct __pyx_obj_10denovonear_10transcript___pyx_scope_struct__insert_region *__pyx_outer_scope;
  PyObject *__pyx_v_x;
  PyObject *__pyx_t_0;
  Py_ssize_t __pyx_t_1;
};


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  #define __Pyx_GIVEREF(r)
  #define __Pyx_XINCREF(r) Py_XINCREF(r)
  #define __Pyx_XDECREF(r) Py_XDECREF(r)
  #define __Pyx_XGOTREF(r)
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#define __Pyx_XDECREF_SET(r, v) do {\
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        r = v; __Pyx_XDECREF(tmp);\
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#define __Pyx_DECREF_SET(r, v) do {\
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#define __Pyx_CLEAR(r)    do { PyObject* tmp = ((PyObject*)(r)); r = NULL; __Pyx_DECREF(tmp);} while(0)
#define __Pyx_XCLEAR(r)   do { if((r) != NULL) {PyObject* tmp = ((PyObject*)(r)); r = NULL; __Pyx_DECREF(tmp);}} while(0)

/* PyObjectGetAttrStr.proto */
#if CYTHON_USE_TYPE_SLOTS
static CYTHON_INLINE PyObject* __Pyx_PyObject_GetAttrStr(PyObject* obj, PyObject* attr_name) {
    PyTypeObject* tp = Py_TYPE(obj);
    if (likely(tp->tp_getattro))
        return tp->tp_getattro(obj, attr_name);
#if PY_MAJOR_VERSION < 3
    if (likely(tp->tp_getattr))
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    return PyObject_GetAttr(obj, attr_name);
}
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#define __Pyx_PyObject_GetAttrStr(o,n) PyObject_GetAttr(o,n)
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/* GetBuiltinName.proto */
static PyObject *__Pyx_GetBuiltinName(PyObject *name);

/* RaiseArgTupleInvalid.proto */
static void __Pyx_RaiseArgtupleInvalid(const char* func_name, int exact,
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/* RaiseDoubleKeywords.proto */
static void __Pyx_RaiseDoubleKeywordsError(const char* func_name, PyObject* kw_name);

/* ParseKeywords.proto */
static int __Pyx_ParseOptionalKeywords(PyObject *kwds, PyObject **argnames[],\
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/* PyObjectCall.proto */
#if CYTHON_COMPILING_IN_CPYTHON
static CYTHON_INLINE PyObject* __Pyx_PyObject_Call(PyObject *func, PyObject *arg, PyObject *kw);
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#define __Pyx_PyObject_Call(func, arg, kw) PyObject_Call(func, arg, kw)
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/* UnicodeAsUCS4.proto */
static CYTHON_INLINE Py_UCS4 __Pyx_PyUnicode_AsPy_UCS4(PyObject*);

/* object_ord.proto */
#if PY_MAJOR_VERSION >= 3
#define __Pyx_PyObject_Ord(c)\
    (likely(PyUnicode_Check(c)) ? (long)__Pyx_PyUnicode_AsPy_UCS4(c) : __Pyx__PyObject_Ord(c))
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#define __Pyx_PyObject_Ord(c) __Pyx__PyObject_Ord(c)
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static long __Pyx__PyObject_Ord(PyObject* c);

/* PyFunctionFastCall.proto */
#if CYTHON_FAST_PYCALL
#define __Pyx_PyFunction_FastCall(func, args, nargs)\
    __Pyx_PyFunction_FastCallDict((func), (args), (nargs), NULL)
#if 1 || PY_VERSION_HEX < 0x030600B1
static PyObject *__Pyx_PyFunction_FastCallDict(PyObject *func, PyObject **args, int nargs, PyObject *kwargs);
#else
#define __Pyx_PyFunction_FastCallDict(func, args, nargs, kwargs) _PyFunction_FastCallDict(func, args, nargs, kwargs)
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#endif

/* PyCFunctionFastCall.proto */
#if CYTHON_FAST_PYCCALL
static CYTHON_INLINE PyObject *__Pyx_PyCFunction_FastCall(PyObject *func, PyObject **args, Py_ssize_t nargs);
#else
#define __Pyx_PyCFunction_FastCall(func, args, nargs)  (assert(0), NULL)
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/* PyObjectCallMethO.proto */
#if CYTHON_COMPILING_IN_CPYTHON
static CYTHON_INLINE PyObject* __Pyx_PyObject_CallMethO(PyObject *func, PyObject *arg);
#endif

/* PyObjectCallOneArg.proto */
static CYTHON_INLINE PyObject* __Pyx_PyObject_CallOneArg(PyObject *func, PyObject *arg);

/* PyObjectCallNoArg.proto */
#if CYTHON_COMPILING_IN_CPYTHON
static CYTHON_INLINE PyObject* __Pyx_PyObject_CallNoArg(PyObject *func);
#else
#define __Pyx_PyObject_CallNoArg(func) __Pyx_PyObject_Call(func, __pyx_empty_tuple, NULL)
#endif

/* ListCompAppend.proto */
#if CYTHON_USE_PYLIST_INTERNALS && CYTHON_ASSUME_SAFE_MACROS
static CYTHON_INLINE int __Pyx_ListComp_Append(PyObject* list, PyObject* x) {
    PyListObject* L = (PyListObject*) list;
    Py_ssize_t len = Py_SIZE(list);
    if (likely(L->allocated > len)) {
        Py_INCREF(x);
        PyList_SET_ITEM(list, len, x);
        Py_SIZE(list) = len+1;
        return 0;
    }
    return PyList_Append(list, x);
}
#else
#define __Pyx_ListComp_Append(L,x) PyList_Append(L,x)
#endif

/* SliceObject.proto */
static CYTHON_INLINE PyObject* __Pyx_PyObject_GetSlice(
        PyObject* obj, Py_ssize_t cstart, Py_ssize_t cstop,
        PyObject** py_start, PyObject** py_stop, PyObject** py_slice,
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/* IncludeStringH.proto */
#include <string.h>

/* BytesEquals.proto */
static CYTHON_INLINE int __Pyx_PyBytes_Equals(PyObject* s1, PyObject* s2, int equals);

/* UnicodeEquals.proto */
static CYTHON_INLINE int __Pyx_PyUnicode_Equals(PyObject* s1, PyObject* s2, int equals);

/* StrEquals.proto */
#if PY_MAJOR_VERSION >= 3
#define __Pyx_PyString_Equals __Pyx_PyUnicode_Equals
#else
#define __Pyx_PyString_Equals __Pyx_PyBytes_Equals
#endif

/* PyIntBinop.proto */
#if !CYTHON_COMPILING_IN_PYPY
static PyObject* __Pyx_PyInt_EqObjC(PyObject *op1, PyObject *op2, long intval, int inplace);
#else
#define __Pyx_PyInt_EqObjC(op1, op2, intval, inplace)\
    PyObject_RichCompare(op1, op2, Py_EQ)
    #endif

/* PyThreadStateGet.proto */
#if CYTHON_FAST_THREAD_STATE
#define __Pyx_PyThreadState_declare  PyThreadState *__pyx_tstate;
#define __Pyx_PyThreadState_assign  __pyx_tstate = PyThreadState_GET();
#else
#define __Pyx_PyThreadState_declare
#define __Pyx_PyThreadState_assign
#endif

/* PyErrFetchRestore.proto */
#if CYTHON_FAST_THREAD_STATE
#define __Pyx_ErrRestoreWithState(type, value, tb)  __Pyx_ErrRestoreInState(PyThreadState_GET(), type, value, tb)
#define __Pyx_ErrFetchWithState(type, value, tb)    __Pyx_ErrFetchInState(PyThreadState_GET(), type, value, tb)
#define __Pyx_ErrRestore(type, value, tb)  __Pyx_ErrRestoreInState(__pyx_tstate, type, value, tb)
#define __Pyx_ErrFetch(type, value, tb)    __Pyx_ErrFetchInState(__pyx_tstate, type, value, tb)
static CYTHON_INLINE void __Pyx_ErrRestoreInState(PyThreadState *tstate, PyObject *type, PyObject *value, PyObject *tb);
static CYTHON_INLINE void __Pyx_ErrFetchInState(PyThreadState *tstate, PyObject **type, PyObject **value, PyObject **tb);
#else
#define __Pyx_ErrRestoreWithState(type, value, tb)  PyErr_Restore(type, value, tb)
#define __Pyx_ErrFetchWithState(type, value, tb)  PyErr_Fetch(type, value, tb)
#define __Pyx_ErrRestore(type, value, tb)  PyErr_Restore(type, value, tb)
#define __Pyx_ErrFetch(type, value, tb)  PyErr_Fetch(type, value, tb)
#endif

/* RaiseException.proto */
static void __Pyx_Raise(PyObject *type, PyObject *value, PyObject *tb, PyObject *cause);

/* PyIntBinop.proto */
#if !CYTHON_COMPILING_IN_PYPY
static PyObject* __Pyx_PyInt_AddObjC(PyObject *op1, PyObject *op2, long intval, int inplace);
#else
#define __Pyx_PyInt_AddObjC(op1, op2, intval, inplace)\
    (inplace ? PyNumber_InPlaceAdd(op1, op2) : PyNumber_Add(op1, op2))
#endif

/* None.proto */
static CYTHON_INLINE void __Pyx_RaiseClosureNameError(const char *varname);

/* GetModuleGlobalName.proto */
static CYTHON_INLINE PyObject *__Pyx_GetModuleGlobalName(PyObject *name);

/* RaiseTooManyValuesToUnpack.proto */
static CYTHON_INLINE void __Pyx_RaiseTooManyValuesError(Py_ssize_t expected);

/* RaiseNeedMoreValuesToUnpack.proto */
static CYTHON_INLINE void __Pyx_RaiseNeedMoreValuesError(Py_ssize_t index);

/* IterFinish.proto */
static CYTHON_INLINE int __Pyx_IterFinish(void);

/* UnpackItemEndCheck.proto */
static int __Pyx_IternextUnpackEndCheck(PyObject *retval, Py_ssize_t expected);

/* FetchCommonType.proto */
static PyTypeObject* __Pyx_FetchCommonType(PyTypeObject* type);

/* CythonFunction.proto */
#define __Pyx_CyFunction_USED 1
#include <structmember.h>
#define __Pyx_CYFUNCTION_STATICMETHOD  0x01
#define __Pyx_CYFUNCTION_CLASSMETHOD   0x02
#define __Pyx_CYFUNCTION_CCLASS        0x04
#define __Pyx_CyFunction_GetClosure(f)\
    (((__pyx_CyFunctionObject *) (f))->func_closure)
#define __Pyx_CyFunction_GetClassObj(f)\
    (((__pyx_CyFunctionObject *) (f))->func_classobj)
#define __Pyx_CyFunction_Defaults(type, f)\
    ((type *)(((__pyx_CyFunctionObject *) (f))->defaults))
#define __Pyx_CyFunction_SetDefaultsGetter(f, g)\
    ((__pyx_CyFunctionObject *) (f))->defaults_getter = (g)
typedef struct {
    PyCFunctionObject func;
#if PY_VERSION_HEX < 0x030500A0
    PyObject *func_weakreflist;
#endif
    PyObject *func_dict;
    PyObject *func_name;
    PyObject *func_qualname;
    PyObject *func_doc;
    PyObject *func_globals;
    PyObject *func_code;
    PyObject *func_closure;
    PyObject *func_classobj;
    void *defaults;
    int defaults_pyobjects;
    int flags;
    PyObject *defaults_tuple;
    PyObject *defaults_kwdict;
    PyObject *(*defaults_getter)(PyObject *);
    PyObject *func_annotations;
} __pyx_CyFunctionObject;
static PyTypeObject *__pyx_CyFunctionType = 0;
#define __Pyx_CyFunction_NewEx(ml, flags, qualname, self, module, globals, code)\
    __Pyx_CyFunction_New(__pyx_CyFunctionType, ml, flags, qualname, self, module, globals, code)
static PyObject *__Pyx_CyFunction_New(PyTypeObject *, PyMethodDef *ml,
                                      int flags, PyObject* qualname,
                                      PyObject *self,
                                      PyObject *module, PyObject *globals,
                                      PyObject* code);
static CYTHON_INLINE void *__Pyx_CyFunction_InitDefaults(PyObject *m,
                                                         size_t size,
                                                         int pyobjects);
static CYTHON_INLINE void __Pyx_CyFunction_SetDefaultsTuple(PyObject *m,
                                                            PyObject *tuple);
static CYTHON_INLINE void __Pyx_CyFunction_SetDefaultsKwDict(PyObject *m,
                                                             PyObject *dict);
static CYTHON_INLINE void __Pyx_CyFunction_SetAnnotationsDict(PyObject *m,
                                                              PyObject *dict);
static int __pyx_CyFunction_init(void);

/* IncludeCppStringH.proto */
#include <string>

/* decode_c_string_utf16.proto */
static CYTHON_INLINE PyObject *__Pyx_PyUnicode_DecodeUTF16(const char *s, Py_ssize_t size, const char *errors) {
    int byteorder = 0;
    return PyUnicode_DecodeUTF16(s, size, errors, &byteorder);
}
static CYTHON_INLINE PyObject *__Pyx_PyUnicode_DecodeUTF16LE(const char *s, Py_ssize_t size, const char *errors) {
    int byteorder = -1;
    return PyUnicode_DecodeUTF16(s, size, errors, &byteorder);
}
static CYTHON_INLINE PyObject *__Pyx_PyUnicode_DecodeUTF16BE(const char *s, Py_ssize_t size, const char *errors) {
    int byteorder = 1;
    return PyUnicode_DecodeUTF16(s, size, errors, &byteorder);
}

/* decode_c_bytes.proto */
static CYTHON_INLINE PyObject* __Pyx_decode_c_bytes(
         const char* cstring, Py_ssize_t length, Py_ssize_t start, Py_ssize_t stop,
         const char* encoding, const char* errors,
         PyObject* (*decode_func)(const char *s, Py_ssize_t size, const char *errors));

/* decode_cpp_string.proto */
static CYTHON_INLINE PyObject* __Pyx_decode_cpp_string(
         std::string cppstring, Py_ssize_t start, Py_ssize_t stop,
         const char* encoding, const char* errors,
         PyObject* (*decode_func)(const char *s, Py_ssize_t size, const char *errors)) {
    return __Pyx_decode_c_bytes(
        cppstring.data(), cppstring.size(), start, stop, encoding, errors, decode_func);
}

/* DictGetItem.proto */
#if PY_MAJOR_VERSION >= 3 && !CYTHON_COMPILING_IN_PYPY
static PyObject *__Pyx_PyDict_GetItem(PyObject *d, PyObject* key) {
    PyObject *value;
    value = PyDict_GetItemWithError(d, key);
    if (unlikely(!value)) {
        if (!PyErr_Occurred()) {
            PyObject* args = PyTuple_Pack(1, key);
            if (likely(args))
                PyErr_SetObject(PyExc_KeyError, args);
            Py_XDECREF(args);
        }
        return NULL;
    }
    Py_INCREF(value);
    return value;
}
#else
    #define __Pyx_PyDict_GetItem(d, key) PyObject_GetItem(d, key)
#endif

/* SetupReduce.proto */
static int __Pyx_setup_reduce(PyObject* type_obj);

/* Import.proto */
static PyObject *__Pyx_Import(PyObject *name, PyObject *from_list, int level);

/* ImportFrom.proto */
static PyObject* __Pyx_ImportFrom(PyObject* module, PyObject* name);

/* CLineInTraceback.proto */
static int __Pyx_CLineForTraceback(int c_line);

/* CodeObjectCache.proto */
typedef struct {
    PyCodeObject* code_object;
    int code_line;
} __Pyx_CodeObjectCacheEntry;
struct __Pyx_CodeObjectCache {
    int count;
    int max_count;
    __Pyx_CodeObjectCacheEntry* entries;
};
static struct __Pyx_CodeObjectCache __pyx_code_cache = {0,0,NULL};
static int __pyx_bisect_code_objects(__Pyx_CodeObjectCacheEntry* entries, int count, int code_line);
static PyCodeObject *__pyx_find_code_object(int code_line);
static void __pyx_insert_code_object(int code_line, PyCodeObject* code_object);

/* AddTraceback.proto */
static void __Pyx_AddTraceback(const char *funcname, int c_line,
                               int py_line, const char *filename);

/* CIntToPy.proto */
static CYTHON_INLINE PyObject* __Pyx_PyInt_From_int(int value);

/* CppExceptionConversion.proto */
#ifndef __Pyx_CppExn2PyErr
#include <new>
#include <typeinfo>
#include <stdexcept>
#include <ios>
static void __Pyx_CppExn2PyErr() {
  try {
    if (PyErr_Occurred())
      ; // let the latest Python exn pass through and ignore the current one
    else
      throw;
  } catch (const std::bad_alloc& exn) {
    PyErr_SetString(PyExc_MemoryError, exn.what());
  } catch (const std::bad_cast& exn) {
    PyErr_SetString(PyExc_TypeError, exn.what());
  } catch (const std::bad_typeid& exn) {
    PyErr_SetString(PyExc_TypeError, exn.what());
  } catch (const std::domain_error& exn) {
    PyErr_SetString(PyExc_ValueError, exn.what());
  } catch (const std::invalid_argument& exn) {
    PyErr_SetString(PyExc_ValueError, exn.what());
  } catch (const std::ios_base::failure& exn) {
    PyErr_SetString(PyExc_IOError, exn.what());
  } catch (const std::out_of_range& exn) {
    PyErr_SetString(PyExc_IndexError, exn.what());
  } catch (const std::overflow_error& exn) {
    PyErr_SetString(PyExc_OverflowError, exn.what());
  } catch (const std::range_error& exn) {
    PyErr_SetString(PyExc_ArithmeticError, exn.what());
  } catch (const std::underflow_error& exn) {
    PyErr_SetString(PyExc_ArithmeticError, exn.what());
  } catch (const std::exception& exn) {
    PyErr_SetString(PyExc_RuntimeError, exn.what());
  }
  catch (...)
  {
    PyErr_SetString(PyExc_RuntimeError, "Unknown exception");
  }
}
#endif

static PyObject* __pyx_convert__to_py_struct__Region(struct Region s);
/* CIntToPy.proto */
static CYTHON_INLINE PyObject* __Pyx_PyInt_From_char(char value);

static PyObject* __pyx_convert__to_py_struct__Codon(struct Codon s);
/* CIntFromPy.proto */
static CYTHON_INLINE int __Pyx_PyInt_As_int(PyObject *);

/* CIntFromPy.proto */
static CYTHON_INLINE size_t __Pyx_PyInt_As_size_t(PyObject *);

/* CIntToPy.proto */
static CYTHON_INLINE PyObject* __Pyx_PyInt_From_long(long value);

/* CIntFromPy.proto */
static CYTHON_INLINE long __Pyx_PyInt_As_long(PyObject *);

/* SwapException.proto */
#if CYTHON_FAST_THREAD_STATE
#define __Pyx_ExceptionSwap(type, value, tb)  __Pyx__ExceptionSwap(__pyx_tstate, type, value, tb)
static CYTHON_INLINE void __Pyx__ExceptionSwap(PyThreadState *tstate, PyObject **type, PyObject **value, PyObject **tb);
#else
static CYTHON_INLINE void __Pyx_ExceptionSwap(PyObject **type, PyObject **value, PyObject **tb);
#endif

/* PyObjectCallMethod1.proto */
static PyObject* __Pyx_PyObject_CallMethod1(PyObject* obj, PyObject* method_name, PyObject* arg);

/* CoroutineBase.proto */
typedef PyObject *(*__pyx_coroutine_body_t)(PyObject *, PyObject *);
typedef struct {
    PyObject_HEAD
    __pyx_coroutine_body_t body;
    PyObject *closure;
    PyObject *exc_type;
    PyObject *exc_value;
    PyObject *exc_traceback;
    PyObject *gi_weakreflist;
    PyObject *classobj;
    PyObject *yieldfrom;
    PyObject *gi_name;
    PyObject *gi_qualname;
    PyObject *gi_modulename;
    int resume_label;
    char is_running;
} __pyx_CoroutineObject;
static __pyx_CoroutineObject *__Pyx__Coroutine_New(
    PyTypeObject *type, __pyx_coroutine_body_t body, PyObject *closure,
    PyObject *name, PyObject *qualname, PyObject *module_name);
static int __Pyx_Coroutine_clear(PyObject *self);
#if 1 || PY_VERSION_HEX < 0x030300B0
static int __Pyx_PyGen_FetchStopIterationValue(PyObject **pvalue);
#else
#define __Pyx_PyGen_FetchStopIterationValue(pvalue) PyGen_FetchStopIterationValue(pvalue)
#endif

/* PatchModuleWithCoroutine.proto */
static PyObject* __Pyx_Coroutine_patch_module(PyObject* module, const char* py_code);

/* PatchGeneratorABC.proto */
static int __Pyx_patch_abc(void);

/* Generator.proto */
#define __Pyx_Generator_USED
static PyTypeObject *__pyx_GeneratorType = 0;
#define __Pyx_Generator_CheckExact(obj) (Py_TYPE(obj) == __pyx_GeneratorType)
#define __Pyx_Generator_New(body, closure, name, qualname, module_name)\
    __Pyx__Coroutine_New(__pyx_GeneratorType, body, closure, name, qualname, module_name)
static PyObject *__Pyx_Generator_Next(PyObject *self);
static int __pyx_Generator_init(void);

/* CheckBinaryVersion.proto */
static int __Pyx_check_binary_version(void);

/* InitStrings.proto */
static int __Pyx_InitStrings(__Pyx_StringTabEntry *t);


/* Module declarations from 'libcpp.vector' */

/* Module declarations from 'libc.string' */

/* Module declarations from 'libcpp.string' */

/* Module declarations from 'libcpp' */

/* Module declarations from 'denovonear.transcript' */
static PyTypeObject *__pyx_ptype_10denovonear_10transcript_Transcript = 0;
static PyTypeObject *__pyx_ptype_10denovonear_10transcript___pyx_scope_struct__insert_region = 0;
static PyTypeObject *__pyx_ptype_10denovonear_10transcript___pyx_scope_struct_1_genexpr = 0;
static PyTypeObject *__pyx_ptype_10denovonear_10transcript___pyx_scope_struct_2_genexpr = 0;
static std::string __pyx_convert_string_from_py_std__in_string(PyObject *); /*proto*/
static CYTHON_INLINE PyObject *__pyx_convert_PyObject_string_to_py_std__in_string(std::string const &); /*proto*/
static CYTHON_INLINE PyObject *__pyx_convert_PyUnicode_string_to_py_std__in_string(std::string const &); /*proto*/
static CYTHON_INLINE PyObject *__pyx_convert_PyStr_string_to_py_std__in_string(std::string const &); /*proto*/
static CYTHON_INLINE PyObject *__pyx_convert_PyBytes_string_to_py_std__in_string(std::string const &); /*proto*/
static CYTHON_INLINE PyObject *__pyx_convert_PyByteArray_string_to_py_std__in_string(std::string const &); /*proto*/
static std::vector<int>  __pyx_convert_vector_from_py_int(PyObject *); /*proto*/
static std::vector<std::vector<int> >  __pyx_convert_vector_from_py_std_3a__3a_vector_3c_int_3e___(PyObject *); /*proto*/
static PyObject *__pyx_convert_vector_to_py_struct__Region(const std::vector<struct Region>  &); /*proto*/
#define __Pyx_MODULE_NAME "denovonear.transcript"
int __pyx_module_is_main_denovonear__transcript = 0;

/* Implementation of 'denovonear.transcript' */
static PyObject *__pyx_builtin_NotImplementedError;
static PyObject *__pyx_builtin_ValueError;
static PyObject *__pyx_builtin_enumerate;
static PyObject *__pyx_builtin_min;
static PyObject *__pyx_builtin_max;
static PyObject *__pyx_builtin_sorted;
static PyObject *__pyx_builtin_chr;
static PyObject *__pyx_builtin_TypeError;
static PyObject *__pyx_builtin_range;
static const char __pyx_k_N[] = "N";
static const char __pyx_k__5[] = "";
static const char __pyx_k__6[] = "\"";
static const char __pyx_k__8[] = "{}:{}";
static const char __pyx_k_bp[] = "...[{} bp]...";
static const char __pyx_k_cds[] = "cds";
static const char __pyx_k_chr[] = "chr";
static const char __pyx_k_end[] = "end";
static const char __pyx_k_key[] = "key";
static const char __pyx_k_max[] = "max";
static const char __pyx_k_min[] = "min";
static const char __pyx_k_pos[] = "pos";
static const char __pyx_k_args[] = "args";
static const char __pyx_k_exon[] = "exon";
static const char __pyx_k_hash[] = "__hash__";
static const char __pyx_k_main[] = "__main__";
static const char __pyx_k_name[] = "name";
static const char __pyx_k_repr[] = "__repr__";
static const char __pyx_k_send[] = "send";
static const char __pyx_k_test[] = "__test__";
static const char __pyx_k_text[] = "text";
static const char __pyx_k_utf8[] = "utf8";
static const char __pyx_k_chrom[] = "chrom";
static const char __pyx_k_close[] = "close";
static const char __pyx_k_exons[] = "exons";
static const char __pyx_k_first[] = "first";
static const char __pyx_k_pos_1[] = "pos_1";
static const char __pyx_k_pos_2[] = "pos_2";
static const char __pyx_k_range[] = "range";
static const char __pyx_k_start[] = "start";
static const char __pyx_k_throw[] = "throw";
static const char __pyx_k_coords[] = "coords";
static const char __pyx_k_decode[] = "decode";
static const char __pyx_k_encode[] = "encode";
static const char __pyx_k_format[] = "format";
static const char __pyx_k_import[] = "__import__";
static const char __pyx_k_length[] = "length";
static const char __pyx_k_name_2[] = "__name__";
static const char __pyx_k_offset[] = "offset";
static const char __pyx_k_reduce[] = "__reduce__";
static const char __pyx_k_region[] = "region";
static const char __pyx_k_second[] = "second";
static const char __pyx_k_sorted[] = "sorted";
static const char __pyx_k_strand[] = "strand";
static const char __pyx_k_cds_pos[] = "cds_pos";
static const char __pyx_k_genexpr[] = "genexpr";
static const char __pyx_k_get_cds[] = "get_cds";
static const char __pyx_k_get_end[] = "get_end";
static const char __pyx_k_regions[] = "regions";
static const char __pyx_k_reverse[] = "reverse";
static const char __pyx_k_set_cds[] = "set_cds";
static const char __pyx_k_get_name[] = "get_name";
static const char __pyx_k_getstate[] = "__getstate__";
static const char __pyx_k_position[] = "position";
static const char __pyx_k_sequence[] = "sequence";
static const char __pyx_k_setstate[] = "__setstate__";
static const char __pyx_k_TypeError[] = "TypeError";
static const char __pyx_k_codon_seq[] = "codon_seq";
static const char __pyx_k_enumerate[] = "enumerate";
static const char __pyx_k_get_chrom[] = "get_chrom";
static const char __pyx_k_get_exons[] = "get_exons";
static const char __pyx_k_get_start[] = "get_start";
static const char __pyx_k_itertools[] = "itertools";
static const char __pyx_k_reduce_ex[] = "__reduce_ex__";
static const char __pyx_k_set_exons[] = "set_exons";
static const char __pyx_k_ValueError[] = "ValueError";
static const char __pyx_k_cds_ranges[] = "cds_ranges";
static const char __pyx_k_get_strand[] = "get_strand";
static const char __pyx_k_initial_aa[] = "initial_aa";
static const char __pyx_k_exon_ranges[] = "exon_ranges";
static const char __pyx_k_intra_codon[] = "intra_codon";
static const char __pyx_k_codon_number[] = "codon_number";
static const char __pyx_k_combinations[] = "combinations";
static const char __pyx_k_get_overlaps[] = "get_overlaps";
static const char __pyx_k_insert_region[] = "insert_region";
static const char __pyx_k_reduce_cython[] = "__reduce_cython__";
static const char __pyx_k_setstate_cython[] = "__setstate_cython__";
static const char __pyx_k_merge_coordinates[] = "merge_coordinates";
static const char __pyx_k_merge_genomic_seq[] = "merge_genomic_seq";
static const char __pyx_k_cline_in_traceback[] = "cline_in_traceback";
static const char __pyx_k_get_genomic_offset[] = "get_genomic_offset";
static const char __pyx_k_NotImplementedError[] = "NotImplementedError";
static const char __pyx_k_add_genomic_sequence[] = "add_genomic_sequence";
static const char __pyx_k_get_genomic_sequence[] = "get_genomic_sequence";
static const char __pyx_k_denovonear_transcript[] = "denovonear.transcript";
static const char __pyx_k_op_0_isn_t_implemented_yet[] = "op {0} isn't implemented yet";
static const char __pyx_k_insert_region_locals_genexpr[] = "insert_region.<locals>.genexpr";
static const char __pyx_k_Copyright_c_2015_Genome_Researc[] = "\nCopyright (c) 2015 Genome Research Ltd.\n\nPermission is hereby granted, free of charge, to any person obtaining a copy of\nthis software and associated documentation files (the \"Software\"), to deal in\nthe Software without restriction, including without limitation the rights to\nuse, copy, modify, merge, publish, distribute, sublicense, and/or sell copies\nof the Software, and to permit persons to whom the Software is furnished to do\nso, subject to the following conditions:\n\nThe above copyright notice and this permission notice shall be included in all\ncopies or substantial portions of the Software.\n\nTHE SOFTWARE IS PROVIDED \"AS IS\", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR\nIMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS\nFOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR\nCOPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER\nIN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN\nCONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE.\n";
static const char __pyx_k_Transcript_name_chrom_start_end[] = "Transcript(name=\"{}\", chrom=\"{}\", start={}, end={}, strand=\"{}\", exons={}, cds={}, sequence={}, offset={})";
static const char __pyx_k_merge_coordinates_locals_lambda[] = "merge_coordinates.<locals>.<lambda>";
static const char __pyx_k_CDS_coordinates_were_not_supplie[] = "CDS coordinates were not supplied.";
static const char __pyx_k_no_default___reduce___due_to_non[] = "no default __reduce__ due to non-trivial __cinit__";
static PyObject *__pyx_kp_s_CDS_coordinates_were_not_supplie;
static PyObject *__pyx_n_s_N;
static PyObject *__pyx_n_s_NotImplementedError;
static PyObject *__pyx_kp_s_Transcript_name_chrom_start_end;
static PyObject *__pyx_n_s_TypeError;
static PyObject *__pyx_n_s_ValueError;
static PyObject *__pyx_kp_s__5;
static PyObject *__pyx_kp_s__6;
static PyObject *__pyx_kp_s__8;
static PyObject *__pyx_n_s_add_genomic_sequence;
static PyObject *__pyx_n_s_args;
static PyObject *__pyx_kp_s_bp;
static PyObject *__pyx_n_s_cds;
static PyObject *__pyx_n_s_cds_pos;
static PyObject *__pyx_n_s_cds_ranges;
static PyObject *__pyx_n_s_chr;
static PyObject *__pyx_n_s_chrom;
static PyObject *__pyx_n_s_cline_in_traceback;
static PyObject *__pyx_n_s_close;
static PyObject *__pyx_n_s_codon_number;
static PyObject *__pyx_n_s_codon_seq;
static PyObject *__pyx_n_s_combinations;
static PyObject *__pyx_n_s_coords;
static PyObject *__pyx_n_s_decode;
static PyObject *__pyx_n_s_denovonear_transcript;
static PyObject *__pyx_n_s_encode;
static PyObject *__pyx_n_s_end;
static PyObject *__pyx_n_s_enumerate;
static PyObject *__pyx_n_s_exon;
static PyObject *__pyx_n_s_exon_ranges;
static PyObject *__pyx_n_s_exons;
static PyObject *__pyx_n_s_first;
static PyObject *__pyx_n_s_format;
static PyObject *__pyx_n_s_genexpr;
static PyObject *__pyx_n_s_get_cds;
static PyObject *__pyx_n_s_get_chrom;
static PyObject *__pyx_n_s_get_end;
static PyObject *__pyx_n_s_get_exons;
static PyObject *__pyx_n_s_get_genomic_offset;
static PyObject *__pyx_n_s_get_genomic_sequence;
static PyObject *__pyx_n_s_get_name;
static PyObject *__pyx_n_s_get_overlaps;
static PyObject *__pyx_n_s_get_start;
static PyObject *__pyx_n_s_get_strand;
static PyObject *__pyx_n_s_getstate;
static PyObject *__pyx_n_s_hash;
static PyObject *__pyx_n_s_import;
static PyObject *__pyx_n_s_initial_aa;
static PyObject *__pyx_n_s_insert_region;
static PyObject *__pyx_n_s_insert_region_locals_genexpr;
static PyObject *__pyx_n_s_intra_codon;
static PyObject *__pyx_n_s_itertools;
static PyObject *__pyx_n_s_key;
static PyObject *__pyx_n_s_length;
static PyObject *__pyx_n_s_main;
static PyObject *__pyx_n_s_max;
static PyObject *__pyx_n_s_merge_coordinates;
static PyObject *__pyx_n_s_merge_coordinates_locals_lambda;
static PyObject *__pyx_n_s_merge_genomic_seq;
static PyObject *__pyx_n_s_min;
static PyObject *__pyx_n_s_name;
static PyObject *__pyx_n_s_name_2;
static PyObject *__pyx_kp_s_no_default___reduce___due_to_non;
static PyObject *__pyx_n_s_offset;
static PyObject *__pyx_kp_s_op_0_isn_t_implemented_yet;
static PyObject *__pyx_n_s_pos;
static PyObject *__pyx_n_s_pos_1;
static PyObject *__pyx_n_s_pos_2;
static PyObject *__pyx_n_s_position;
static PyObject *__pyx_n_s_range;
static PyObject *__pyx_n_s_reduce;
static PyObject *__pyx_n_s_reduce_cython;
static PyObject *__pyx_n_s_reduce_ex;
static PyObject *__pyx_n_s_region;
static PyObject *__pyx_n_s_regions;
static PyObject *__pyx_n_s_repr;
static PyObject *__pyx_n_s_reverse;
static PyObject *__pyx_n_s_second;
static PyObject *__pyx_n_s_send;
static PyObject *__pyx_n_s_sequence;
static PyObject *__pyx_n_s_set_cds;
static PyObject *__pyx_n_s_set_exons;
static PyObject *__pyx_n_s_setstate;
static PyObject *__pyx_n_s_setstate_cython;
static PyObject *__pyx_n_s_sorted;
static PyObject *__pyx_n_s_start;
static PyObject *__pyx_n_s_strand;
static PyObject *__pyx_n_s_test;
static PyObject *__pyx_n_s_text;
static PyObject *__pyx_n_s_throw;
static PyObject *__pyx_n_s_utf8;
static int __pyx_pf_10denovonear_10transcript_10Transcript___cinit__(struct __pyx_obj_10denovonear_10transcript_Transcript *__pyx_v_self, PyObject *__pyx_v_name, PyObject *__pyx_v_chrom, PyObject *__pyx_v_start, PyObject *__pyx_v_end, PyObject *__pyx_v_strand, PyObject *__pyx_v_exons, PyObject *__pyx_v_cds, PyObject *__pyx_v_sequence, PyObject *__pyx_v_offset); /* proto */
static void __pyx_pf_10denovonear_10transcript_10Transcript_2__dealloc__(struct __pyx_obj_10denovonear_10transcript_Transcript *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_10denovonear_10transcript_10Transcript_4__repr__(struct __pyx_obj_10denovonear_10transcript_Transcript *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_10denovonear_10transcript_10Transcript_6__str__(struct __pyx_obj_10denovonear_10transcript_Transcript *__pyx_v_self); /* proto */
static Py_hash_t __pyx_pf_10denovonear_10transcript_10Transcript_8__hash__(struct __pyx_obj_10denovonear_10transcript_Transcript *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_10denovonear_10transcript_10Transcript_10__richcmp__(PyObject *__pyx_v_self, PyObject *__pyx_v_other, PyObject *__pyx_v_op); /* proto */
static PyObject *__pyx_pf_10denovonear_10transcript_10Transcript_12set_exons(struct __pyx_obj_10denovonear_10transcript_Transcript *__pyx_v_self, PyObject *__pyx_v_exon_ranges, PyObject *__pyx_v_cds_ranges); /* proto */
static PyObject *__pyx_pf_10denovonear_10transcript_10Transcript_14get_overlaps(CYTHON_UNUSED struct __pyx_obj_10denovonear_10transcript_Transcript *__pyx_v_self, PyObject *__pyx_v_exon, PyObject *__pyx_v_regions); /* proto */
static PyObject *__pyx_pf_10denovonear_10transcript_10Transcript_13insert_region_genexpr(PyObject *__pyx_self); /* proto */
static PyObject *__pyx_pf_10denovonear_10transcript_10Transcript_13insert_region_3genexpr(PyObject *__pyx_self); /* proto */
static PyObject *__pyx_pf_10denovonear_10transcript_10Transcript_16insert_region(struct __pyx_obj_10denovonear_10transcript_Transcript *__pyx_v_self, PyObject *__pyx_v_coords, PyObject *__pyx_v_region); /* proto */
static PyObject *__pyx_lambda_funcdef_lambda2(CYTHON_UNUSED PyObject *__pyx_self, PyObject *__pyx_v_x); /* proto */
static PyObject *__pyx_pf_10denovonear_10transcript_10Transcript_18merge_coordinates(struct __pyx_obj_10denovonear_10transcript_Transcript *__pyx_v_self, PyObject *__pyx_v_first, PyObject *__pyx_v_second); /* proto */
static PyObject *__pyx_pf_10denovonear_10transcript_10Transcript_20merge_genomic_seq(struct __pyx_obj_10denovonear_10transcript_Transcript *__pyx_v_self, PyObject *__pyx_v_other); /* proto */
static PyObject *__pyx_pf_10denovonear_10transcript_10Transcript_22__add__(PyObject *__pyx_v_self, PyObject *__pyx_v_other); /* proto */
static PyObject *__pyx_pf_10denovonear_10transcript_10Transcript_24set_cds(struct __pyx_obj_10denovonear_10transcript_Transcript *__pyx_v_self, PyObject *__pyx_v_cds_ranges); /* proto */
static PyObject *__pyx_pf_10denovonear_10transcript_10Transcript_26get_genomic_offset(struct __pyx_obj_10denovonear_10transcript_Transcript *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_10denovonear_10transcript_10Transcript_28get_exons(struct __pyx_obj_10denovonear_10transcript_Transcript *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_10denovonear_10transcript_10Transcript_30get_cds(struct __pyx_obj_10denovonear_10transcript_Transcript *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_10denovonear_10transcript_10Transcript_32get_name(struct __pyx_obj_10denovonear_10transcript_Transcript *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_10denovonear_10transcript_10Transcript_34get_chrom(struct __pyx_obj_10denovonear_10transcript_Transcript *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_10denovonear_10transcript_10Transcript_36get_start(struct __pyx_obj_10denovonear_10transcript_Transcript *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_10denovonear_10transcript_10Transcript_38get_end(struct __pyx_obj_10denovonear_10transcript_Transcript *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_10denovonear_10transcript_10Transcript_40get_strand(struct __pyx_obj_10denovonear_10transcript_Transcript *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_10denovonear_10transcript_10Transcript_42get_cds_start(struct __pyx_obj_10denovonear_10transcript_Transcript *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_10denovonear_10transcript_10Transcript_44get_cds_end(struct __pyx_obj_10denovonear_10transcript_Transcript *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_10denovonear_10transcript_10Transcript_46fix_cds_boundary(struct __pyx_obj_10denovonear_10transcript_Transcript *__pyx_v_self, PyObject *__pyx_v_pos); /* proto */
static PyObject *__pyx_pf_10denovonear_10transcript_10Transcript_48in_exons(struct __pyx_obj_10denovonear_10transcript_Transcript *__pyx_v_self, PyObject *__pyx_v_position); /* proto */
static PyObject *__pyx_pf_10denovonear_10transcript_10Transcript_50find_closest_exon(struct __pyx_obj_10denovonear_10transcript_Transcript *__pyx_v_self, PyObject *__pyx_v_position, PyObject *__pyx_v_exons); /* proto */
static PyObject *__pyx_pf_10denovonear_10transcript_10Transcript_52in_coding_region(struct __pyx_obj_10denovonear_10transcript_Transcript *__pyx_v_self, PyObject *__pyx_v_position); /* proto */
static PyObject *__pyx_pf_10denovonear_10transcript_10Transcript_54get_exon_containing_position(struct __pyx_obj_10denovonear_10transcript_Transcript *__pyx_v_self, PyObject *__pyx_v_position, PyObject *__pyx_v_exons); /* proto */
static PyObject *__pyx_pf_10denovonear_10transcript_10Transcript_56get_coding_distance(struct __pyx_obj_10denovonear_10transcript_Transcript *__pyx_v_self, PyObject *__pyx_v_pos_1, PyObject *__pyx_v_pos_2); /* proto */
static PyObject *__pyx_pf_10denovonear_10transcript_10Transcript_58chrom_pos_to_cds(struct __pyx_obj_10denovonear_10transcript_Transcript *__pyx_v_self, PyObject *__pyx_v_pos); /* proto */
static PyObject *__pyx_pf_10denovonear_10transcript_10Transcript_60get_position_on_chrom(struct __pyx_obj_10denovonear_10transcript_Transcript *__pyx_v_self, PyObject *__pyx_v_pos, PyObject *__pyx_v_offset); /* proto */
static PyObject *__pyx_pf_10denovonear_10transcript_10Transcript_62get_codon_number_for_cds_position(struct __pyx_obj_10denovonear_10transcript_Transcript *__pyx_v_self, PyObject *__pyx_v_pos); /* proto */
static PyObject *__pyx_pf_10denovonear_10transcript_10Transcript_64get_position_within_codon(struct __pyx_obj_10denovonear_10transcript_Transcript *__pyx_v_self, PyObject *__pyx_v_pos); /* proto */
static PyObject *__pyx_pf_10denovonear_10transcript_10Transcript_66add_cds_sequence(struct __pyx_obj_10denovonear_10transcript_Transcript *__pyx_v_self, PyObject *__pyx_v_text); /* proto */
static PyObject *__pyx_pf_10denovonear_10transcript_10Transcript_68get_cds_sequence(struct __pyx_obj_10denovonear_10transcript_Transcript *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_10denovonear_10transcript_10Transcript_70add_genomic_sequence(struct __pyx_obj_10denovonear_10transcript_Transcript *__pyx_v_self, PyObject *__pyx_v_text, PyObject *__pyx_v_offset); /* proto */
static PyObject *__pyx_pf_10denovonear_10transcript_10Transcript_72get_genomic_sequence(struct __pyx_obj_10denovonear_10transcript_Transcript *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_10denovonear_10transcript_10Transcript_74reverse_complement(struct __pyx_obj_10denovonear_10transcript_Transcript *__pyx_v_self, PyObject *__pyx_v_text); /* proto */
static PyObject *__pyx_pf_10denovonear_10transcript_10Transcript_76get_centered_sequence(struct __pyx_obj_10denovonear_10transcript_Transcript *__pyx_v_self, PyObject *__pyx_v_pos, PyObject *__pyx_v_length); /* proto */
static PyObject *__pyx_pf_10denovonear_10transcript_10Transcript_78get_codon_sequence(struct __pyx_obj_10denovonear_10transcript_Transcript *__pyx_v_self, PyObject *__pyx_v_pos); /* proto */
static PyObject *__pyx_pf_10denovonear_10transcript_10Transcript_80translate(struct __pyx_obj_10denovonear_10transcript_Transcript *__pyx_v_self, PyObject *__pyx_v_text); /* proto */
static PyObject *__pyx_pf_10denovonear_10transcript_10Transcript_82get_codon_info(struct __pyx_obj_10denovonear_10transcript_Transcript *__pyx_v_self, PyObject *__pyx_v_pos); /* proto */
static PyObject *__pyx_pf_10denovonear_10transcript_10Transcript_84get_boundary_distance(struct __pyx_obj_10denovonear_10transcript_Transcript *__pyx_v_self, PyObject *__pyx_v_pos); /* proto */
static PyObject *__pyx_pf_10denovonear_10transcript_10Transcript_86__reduce_cython__(CYTHON_UNUSED struct __pyx_obj_10denovonear_10transcript_Transcript *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_10denovonear_10transcript_10Transcript_88__setstate_cython__(CYTHON_UNUSED struct __pyx_obj_10denovonear_10transcript_Transcript *__pyx_v_self, CYTHON_UNUSED PyObject *__pyx_v___pyx_state); /* proto */
static PyObject *__pyx_tp_new_10denovonear_10transcript_Transcript(PyTypeObject *t, PyObject *a, PyObject *k); /*proto*/
static PyObject *__pyx_tp_new_10denovonear_10transcript___pyx_scope_struct__insert_region(PyTypeObject *t, PyObject *a, PyObject *k); /*proto*/
static PyObject *__pyx_tp_new_10denovonear_10transcript___pyx_scope_struct_1_genexpr(PyTypeObject *t, PyObject *a, PyObject *k); /*proto*/
static PyObject *__pyx_tp_new_10denovonear_10transcript___pyx_scope_struct_2_genexpr(PyTypeObject *t, PyObject *a, PyObject *k); /*proto*/
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    o = (*t->tp_alloc)(t, 0);
  } else {
    o = (PyObject *) PyBaseObject_Type.tp_new(t, __pyx_empty_tuple, 0);
  }
  if (unlikely(!o)) return 0;
  if (unlikely(__pyx_pw_10denovonear_10transcript_10Transcript_1__cinit__(o, a, k) < 0)) goto bad;
  return o;
  bad:
  Py_DECREF(o); o = 0;
  return NULL;
}

static void __pyx_tp_dealloc_10denovonear_10transcript_Transcript(PyObject *o) {
  #if PY_VERSION_HEX >= 0x030400a1
  if (unlikely(PyType_HasFeature(Py_TYPE(o), Py_TPFLAGS_HAVE_FINALIZE) && Py_TYPE(o)->tp_finalize) && (!PyType_IS_GC(Py_TYPE(o)) || !_PyGC_FINALIZED(o))) {
    if (PyObject_CallFinalizerFromDealloc(o)) return;
  }
  #endif
  {
    PyObject *etype, *eval, *etb;
    PyErr_Fetch(&etype, &eval, &etb);
    ++Py_REFCNT(o);
    __pyx_pw_10denovonear_10transcript_10Transcript_3__dealloc__(o);
    --Py_REFCNT(o);
    PyErr_Restore(etype, eval, etb);
  }
  (*Py_TYPE(o)->tp_free)(o);
}

static PyMethodDef __pyx_methods_10denovonear_10transcript_Transcript[] = {
  {"set_exons", (PyCFunction)__pyx_pw_10denovonear_10transcript_10Transcript_13set_exons, METH_VARARGS|METH_KEYWORDS, __pyx_doc_10denovonear_10transcript_10Transcript_12set_exons},
  {"get_overlaps", (PyCFunction)__pyx_pw_10denovonear_10transcript_10Transcript_15get_overlaps, METH_VARARGS|METH_KEYWORDS, __pyx_doc_10denovonear_10transcript_10Transcript_14get_overlaps},
  {"insert_region", (PyCFunction)__pyx_pw_10denovonear_10transcript_10Transcript_17insert_region, METH_VARARGS|METH_KEYWORDS, __pyx_doc_10denovonear_10transcript_10Transcript_16insert_region},
  {"merge_coordinates", (PyCFunction)__pyx_pw_10denovonear_10transcript_10Transcript_19merge_coordinates, METH_VARARGS|METH_KEYWORDS, __pyx_doc_10denovonear_10transcript_10Transcript_18merge_coordinates},
  {"merge_genomic_seq", (PyCFunction)__pyx_pw_10denovonear_10transcript_10Transcript_21merge_genomic_seq, METH_O, __pyx_doc_10denovonear_10transcript_10Transcript_20merge_genomic_seq},
  {"set_cds", (PyCFunction)__pyx_pw_10denovonear_10transcript_10Transcript_25set_cds, METH_O, __pyx_doc_10denovonear_10transcript_10Transcript_24set_cds},
  {"get_genomic_offset", (PyCFunction)__pyx_pw_10denovonear_10transcript_10Transcript_27get_genomic_offset, METH_NOARGS, 0},
  {"get_exons", (PyCFunction)__pyx_pw_10denovonear_10transcript_10Transcript_29get_exons, METH_NOARGS, 0},
  {"get_cds", (PyCFunction)__pyx_pw_10denovonear_10transcript_10Transcript_31get_cds, METH_NOARGS, 0},
  {"get_name", (PyCFunction)__pyx_pw_10denovonear_10transcript_10Transcript_33get_name, METH_NOARGS, 0},
  {"get_chrom", (PyCFunction)__pyx_pw_10denovonear_10transcript_10Transcript_35get_chrom, METH_NOARGS, 0},
  {"get_start", (PyCFunction)__pyx_pw_10denovonear_10transcript_10Transcript_37get_start, METH_NOARGS, 0},
  {"get_end", (PyCFunction)__pyx_pw_10denovonear_10transcript_10Transcript_39get_end, METH_NOARGS, 0},
  {"get_strand", (PyCFunction)__pyx_pw_10denovonear_10transcript_10Transcript_41get_strand, METH_NOARGS, 0},
  {"get_cds_start", (PyCFunction)__pyx_pw_10denovonear_10transcript_10Transcript_43get_cds_start, METH_NOARGS, 0},
  {"get_cds_end", (PyCFunction)__pyx_pw_10denovonear_10transcript_10Transcript_45get_cds_end, METH_NOARGS, 0},
  {"fix_cds_boundary", (PyCFunction)__pyx_pw_10denovonear_10transcript_10Transcript_47fix_cds_boundary, METH_O, 0},
  {"in_exons", (PyCFunction)__pyx_pw_10denovonear_10transcript_10Transcript_49in_exons, METH_O, __pyx_doc_10denovonear_10transcript_10Transcript_48in_exons},
  {"find_closest_exon", (PyCFunction)__pyx_pw_10denovonear_10transcript_10Transcript_51find_closest_exon, METH_VARARGS|METH_KEYWORDS, __pyx_doc_10denovonear_10transcript_10Transcript_50find_closest_exon},
  {"in_coding_region", (PyCFunction)__pyx_pw_10denovonear_10transcript_10Transcript_53in_coding_region, METH_O, 0},
  {"get_exon_containing_position", (PyCFunction)__pyx_pw_10denovonear_10transcript_10Transcript_55get_exon_containing_position, METH_VARARGS|METH_KEYWORDS, __pyx_doc_10denovonear_10transcript_10Transcript_54get_exon_containing_position},
  {"get_coding_distance", (PyCFunction)__pyx_pw_10denovonear_10transcript_10Transcript_57get_coding_distance, METH_VARARGS|METH_KEYWORDS, 0},
  {"chrom_pos_to_cds", (PyCFunction)__pyx_pw_10denovonear_10transcript_10Transcript_59chrom_pos_to_cds, METH_O, 0},
  {"get_position_on_chrom", (PyCFunction)__pyx_pw_10denovonear_10transcript_10Transcript_61get_position_on_chrom, METH_VARARGS|METH_KEYWORDS, 0},
  {"get_codon_number_for_cds_position", (PyCFunction)__pyx_pw_10denovonear_10transcript_10Transcript_63get_codon_number_for_cds_position, METH_O, 0},
  {"get_position_within_codon", (PyCFunction)__pyx_pw_10denovonear_10transcript_10Transcript_65get_position_within_codon, METH_O, 0},
  {"add_cds_sequence", (PyCFunction)__pyx_pw_10denovonear_10transcript_10Transcript_67add_cds_sequence, METH_O, 0},
  {"get_cds_sequence", (PyCFunction)__pyx_pw_10denovonear_10transcript_10Transcript_69get_cds_sequence, METH_NOARGS, 0},
  {"add_genomic_sequence", (PyCFunction)__pyx_pw_10denovonear_10transcript_10Transcript_71add_genomic_sequence, METH_VARARGS|METH_KEYWORDS, 0},
  {"get_genomic_sequence", (PyCFunction)__pyx_pw_10denovonear_10transcript_10Transcript_73get_genomic_sequence, METH_NOARGS, 0},
  {"reverse_complement", (PyCFunction)__pyx_pw_10denovonear_10transcript_10Transcript_75reverse_complement, METH_O, 0},
  {"get_centered_sequence", (PyCFunction)__pyx_pw_10denovonear_10transcript_10Transcript_77get_centered_sequence, METH_VARARGS|METH_KEYWORDS, 0},
  {"get_codon_sequence", (PyCFunction)__pyx_pw_10denovonear_10transcript_10Transcript_79get_codon_sequence, METH_O, 0},
  {"translate", (PyCFunction)__pyx_pw_10denovonear_10transcript_10Transcript_81translate, METH_O, 0},
  {"get_codon_info", (PyCFunction)__pyx_pw_10denovonear_10transcript_10Transcript_83get_codon_info, METH_O, 0},
  {"get_boundary_distance", (PyCFunction)__pyx_pw_10denovonear_10transcript_10Transcript_85get_boundary_distance, METH_O, 0},
  {"__reduce_cython__", (PyCFunction)__pyx_pw_10denovonear_10transcript_10Transcript_87__reduce_cython__, METH_NOARGS, 0},
  {"__setstate_cython__", (PyCFunction)__pyx_pw_10denovonear_10transcript_10Transcript_89__setstate_cython__, METH_O, 0},
  {0, 0, 0, 0}
};

static PyNumberMethods __pyx_tp_as_number_Transcript = {
  __pyx_pw_10denovonear_10transcript_10Transcript_23__add__, /*nb_add*/
  0, /*nb_subtract*/
  0, /*nb_multiply*/
  #if PY_MAJOR_VERSION < 3 || (CYTHON_COMPILING_IN_PYPY && PY_VERSION_HEX < 0x03050000)
  0, /*nb_divide*/
  #endif
  0, /*nb_remainder*/
  0, /*nb_divmod*/
  0, /*nb_power*/
  0, /*nb_negative*/
  0, /*nb_positive*/
  0, /*nb_absolute*/
  0, /*nb_nonzero*/
  0, /*nb_invert*/
  0, /*nb_lshift*/
  0, /*nb_rshift*/
  0, /*nb_and*/
  0, /*nb_xor*/
  0, /*nb_or*/
  #if PY_MAJOR_VERSION < 3 || (CYTHON_COMPILING_IN_PYPY && PY_VERSION_HEX < 0x03050000)
  0, /*nb_coerce*/
  #endif
  0, /*nb_int*/
  #if PY_MAJOR_VERSION < 3
  0, /*nb_long*/
  #else
  0, /*reserved*/
  #endif
  0, /*nb_float*/
  #if PY_MAJOR_VERSION < 3 || (CYTHON_COMPILING_IN_PYPY && PY_VERSION_HEX < 0x03050000)
  0, /*nb_oct*/
  #endif
  #if PY_MAJOR_VERSION < 3 || (CYTHON_COMPILING_IN_PYPY && PY_VERSION_HEX < 0x03050000)
  0, /*nb_hex*/
  #endif
  0, /*nb_inplace_add*/
  0, /*nb_inplace_subtract*/
  0, /*nb_inplace_multiply*/
  #if PY_MAJOR_VERSION < 3 || (CYTHON_COMPILING_IN_PYPY && PY_VERSION_HEX < 0x03050000)
  0, /*nb_inplace_divide*/
  #endif
  0, /*nb_inplace_remainder*/
  0, /*nb_inplace_power*/
  0, /*nb_inplace_lshift*/
  0, /*nb_inplace_rshift*/
  0, /*nb_inplace_and*/
  0, /*nb_inplace_xor*/
  0, /*nb_inplace_or*/
  0, /*nb_floor_divide*/
  0, /*nb_true_divide*/
  0, /*nb_inplace_floor_divide*/
  0, /*nb_inplace_true_divide*/
  0, /*nb_index*/
  #if PY_VERSION_HEX >= 0x03050000
  0, /*nb_matrix_multiply*/
  #endif
  #if PY_VERSION_HEX >= 0x03050000
  0, /*nb_inplace_matrix_multiply*/
  #endif
};

static PyTypeObject __pyx_type_10denovonear_10transcript_Transcript = {
  PyVarObject_HEAD_INIT(0, 0)
  "denovonear.transcript.Transcript", /*tp_name*/
  sizeof(struct __pyx_obj_10denovonear_10transcript_Transcript), /*tp_basicsize*/
  0, /*tp_itemsize*/
  __pyx_tp_dealloc_10denovonear_10transcript_Transcript, /*tp_dealloc*/
  0, /*tp_print*/
  0, /*tp_getattr*/
  0, /*tp_setattr*/
  #if PY_MAJOR_VERSION < 3
  0, /*tp_compare*/
  #endif
  #if PY_MAJOR_VERSION >= 3
  0, /*tp_as_async*/
  #endif
  __pyx_pw_10denovonear_10transcript_10Transcript_5__repr__, /*tp_repr*/
  &__pyx_tp_as_number_Transcript, /*tp_as_number*/
  0, /*tp_as_sequence*/
  0, /*tp_as_mapping*/
  __pyx_pw_10denovonear_10transcript_10Transcript_9__hash__, /*tp_hash*/
  0, /*tp_call*/
  __pyx_pw_10denovonear_10transcript_10Transcript_7__str__, /*tp_str*/
  0, /*tp_getattro*/
  0, /*tp_setattro*/
  0, /*tp_as_buffer*/
  Py_TPFLAGS_DEFAULT|Py_TPFLAGS_HAVE_VERSION_TAG|Py_TPFLAGS_CHECKTYPES|Py_TPFLAGS_HAVE_NEWBUFFER|Py_TPFLAGS_BASETYPE, /*tp_flags*/
  0, /*tp_doc*/
  0, /*tp_traverse*/
  0, /*tp_clear*/
  __pyx_pw_10denovonear_10transcript_10Transcript_11__richcmp__, /*tp_richcompare*/
  0, /*tp_weaklistoffset*/
  0, /*tp_iter*/
  0, /*tp_iternext*/
  __pyx_methods_10denovonear_10transcript_Transcript, /*tp_methods*/
  0, /*tp_members*/
  0, /*tp_getset*/
  0, /*tp_base*/
  0, /*tp_dict*/
  0, /*tp_descr_get*/
  0, /*tp_descr_set*/
  0, /*tp_dictoffset*/
  0, /*tp_init*/
  0, /*tp_alloc*/
  __pyx_tp_new_10denovonear_10transcript_Transcript, /*tp_new*/
  0, /*tp_free*/
  0, /*tp_is_gc*/
  0, /*tp_bases*/
  0, /*tp_mro*/
  0, /*tp_cache*/
  0, /*tp_subclasses*/
  0, /*tp_weaklist*/
  0, /*tp_del*/
  0, /*tp_version_tag*/
  #if PY_VERSION_HEX >= 0x030400a1
  0, /*tp_finalize*/
  #endif
};

static struct __pyx_obj_10denovonear_10transcript___pyx_scope_struct__insert_region *__pyx_freelist_10denovonear_10transcript___pyx_scope_struct__insert_region[8];
static int __pyx_freecount_10denovonear_10transcript___pyx_scope_struct__insert_region = 0;

static PyObject *__pyx_tp_new_10denovonear_10transcript___pyx_scope_struct__insert_region(PyTypeObject *t, CYTHON_UNUSED PyObject *a, CYTHON_UNUSED PyObject *k) {
  PyObject *o;
  if (CYTHON_COMPILING_IN_CPYTHON && likely((__pyx_freecount_10denovonear_10transcript___pyx_scope_struct__insert_region > 0) & (t->tp_basicsize == sizeof(struct __pyx_obj_10denovonear_10transcript___pyx_scope_struct__insert_region)))) {
    o = (PyObject*)__pyx_freelist_10denovonear_10transcript___pyx_scope_struct__insert_region[--__pyx_freecount_10denovonear_10transcript___pyx_scope_struct__insert_region];
    memset(o, 0, sizeof(struct __pyx_obj_10denovonear_10transcript___pyx_scope_struct__insert_region));
    (void) PyObject_INIT(o, t);
    PyObject_GC_Track(o);
  } else {
    o = (*t->tp_alloc)(t, 0);
    if (unlikely(!o)) return 0;
  }
  return o;
}

static void __pyx_tp_dealloc_10denovonear_10transcript___pyx_scope_struct__insert_region(PyObject *o) {
  struct __pyx_obj_10denovonear_10transcript___pyx_scope_struct__insert_region *p = (struct __pyx_obj_10denovonear_10transcript___pyx_scope_struct__insert_region *)o;
  PyObject_GC_UnTrack(o);
  Py_CLEAR(p->__pyx_v_overlaps);
  Py_CLEAR(p->__pyx_v_region);
  if (CYTHON_COMPILING_IN_CPYTHON && ((__pyx_freecount_10denovonear_10transcript___pyx_scope_struct__insert_region < 8) & (Py_TYPE(o)->tp_basicsize == sizeof(struct __pyx_obj_10denovonear_10transcript___pyx_scope_struct__insert_region)))) {
    __pyx_freelist_10denovonear_10transcript___pyx_scope_struct__insert_region[__pyx_freecount_10denovonear_10transcript___pyx_scope_struct__insert_region++] = ((struct __pyx_obj_10denovonear_10transcript___pyx_scope_struct__insert_region *)o);
  } else {
    (*Py_TYPE(o)->tp_free)(o);
  }
}

static int __pyx_tp_traverse_10denovonear_10transcript___pyx_scope_struct__insert_region(PyObject *o, visitproc v, void *a) {
  int e;
  struct __pyx_obj_10denovonear_10transcript___pyx_scope_struct__insert_region *p = (struct __pyx_obj_10denovonear_10transcript___pyx_scope_struct__insert_region *)o;
  if (p->__pyx_v_overlaps) {
    e = (*v)(p->__pyx_v_overlaps, a); if (e) return e;
  }
  if (p->__pyx_v_region) {
    e = (*v)(p->__pyx_v_region, a); if (e) return e;
  }
  return 0;
}

static int __pyx_tp_clear_10denovonear_10transcript___pyx_scope_struct__insert_region(PyObject *o) {
  PyObject* tmp;
  struct __pyx_obj_10denovonear_10transcript___pyx_scope_struct__insert_region *p = (struct __pyx_obj_10denovonear_10transcript___pyx_scope_struct__insert_region *)o;
  tmp = ((PyObject*)p->__pyx_v_overlaps);
  p->__pyx_v_overlaps = ((PyObject*)Py_None); Py_INCREF(Py_None);
  Py_XDECREF(tmp);
  tmp = ((PyObject*)p->__pyx_v_region);
  p->__pyx_v_region = Py_None; Py_INCREF(Py_None);
  Py_XDECREF(tmp);
  return 0;
}

static PyTypeObject __pyx_type_10denovonear_10transcript___pyx_scope_struct__insert_region = {
  PyVarObject_HEAD_INIT(0, 0)
  "denovonear.transcript.__pyx_scope_struct__insert_region", /*tp_name*/
  sizeof(struct __pyx_obj_10denovonear_10transcript___pyx_scope_struct__insert_region), /*tp_basicsize*/
  0, /*tp_itemsize*/
  __pyx_tp_dealloc_10denovonear_10transcript___pyx_scope_struct__insert_region, /*tp_dealloc*/
  0, /*tp_print*/
  0, /*tp_getattr*/
  0, /*tp_setattr*/
  #if PY_MAJOR_VERSION < 3
  0, /*tp_compare*/
  #endif
  #if PY_MAJOR_VERSION >= 3
  0, /*tp_as_async*/
  #endif
  0, /*tp_repr*/
  0, /*tp_as_number*/
  0, /*tp_as_sequence*/
  0, /*tp_as_mapping*/
  0, /*tp_hash*/
  0, /*tp_call*/
  0, /*tp_str*/
  0, /*tp_getattro*/
  0, /*tp_setattro*/
  0, /*tp_as_buffer*/
  Py_TPFLAGS_DEFAULT|Py_TPFLAGS_HAVE_VERSION_TAG|Py_TPFLAGS_CHECKTYPES|Py_TPFLAGS_HAVE_NEWBUFFER|Py_TPFLAGS_HAVE_GC, /*tp_flags*/
  0, /*tp_doc*/
  __pyx_tp_traverse_10denovonear_10transcript___pyx_scope_struct__insert_region, /*tp_traverse*/
  __pyx_tp_clear_10denovonear_10transcript___pyx_scope_struct__insert_region, /*tp_clear*/
  0, /*tp_richcompare*/
  0, /*tp_weaklistoffset*/
  0, /*tp_iter*/
  0, /*tp_iternext*/
  0, /*tp_methods*/
  0, /*tp_members*/
  0, /*tp_getset*/
  0, /*tp_base*/
  0, /*tp_dict*/
  0, /*tp_descr_get*/
  0, /*tp_descr_set*/
  0, /*tp_dictoffset*/
  0, /*tp_init*/
  0, /*tp_alloc*/
  __pyx_tp_new_10denovonear_10transcript___pyx_scope_struct__insert_region, /*tp_new*/
  0, /*tp_free*/
  0, /*tp_is_gc*/
  0, /*tp_bases*/
  0, /*tp_mro*/
  0, /*tp_cache*/
  0, /*tp_subclasses*/
  0, /*tp_weaklist*/
  0, /*tp_del*/
  0, /*tp_version_tag*/
  #if PY_VERSION_HEX >= 0x030400a1
  0, /*tp_finalize*/
  #endif
};

static struct __pyx_obj_10denovonear_10transcript___pyx_scope_struct_1_genexpr *__pyx_freelist_10denovonear_10transcript___pyx_scope_struct_1_genexpr[8];
static int __pyx_freecount_10denovonear_10transcript___pyx_scope_struct_1_genexpr = 0;

static PyObject *__pyx_tp_new_10denovonear_10transcript___pyx_scope_struct_1_genexpr(PyTypeObject *t, CYTHON_UNUSED PyObject *a, CYTHON_UNUSED PyObject *k) {
  PyObject *o;
  if (CYTHON_COMPILING_IN_CPYTHON && likely((__pyx_freecount_10denovonear_10transcript___pyx_scope_struct_1_genexpr > 0) & (t->tp_basicsize == sizeof(struct __pyx_obj_10denovonear_10transcript___pyx_scope_struct_1_genexpr)))) {
    o = (PyObject*)__pyx_freelist_10denovonear_10transcript___pyx_scope_struct_1_genexpr[--__pyx_freecount_10denovonear_10transcript___pyx_scope_struct_1_genexpr];
    memset(o, 0, sizeof(struct __pyx_obj_10denovonear_10transcript___pyx_scope_struct_1_genexpr));
    (void) PyObject_INIT(o, t);
    PyObject_GC_Track(o);
  } else {
    o = (*t->tp_alloc)(t, 0);
    if (unlikely(!o)) return 0;
  }
  return o;
}

static void __pyx_tp_dealloc_10denovonear_10transcript___pyx_scope_struct_1_genexpr(PyObject *o) {
  struct __pyx_obj_10denovonear_10transcript___pyx_scope_struct_1_genexpr *p = (struct __pyx_obj_10denovonear_10transcript___pyx_scope_struct_1_genexpr *)o;
  PyObject_GC_UnTrack(o);
  Py_CLEAR(p->__pyx_outer_scope);
  Py_CLEAR(p->__pyx_v_x);
  Py_CLEAR(p->__pyx_t_0);
  if (CYTHON_COMPILING_IN_CPYTHON && ((__pyx_freecount_10denovonear_10transcript___pyx_scope_struct_1_genexpr < 8) & (Py_TYPE(o)->tp_basicsize == sizeof(struct __pyx_obj_10denovonear_10transcript___pyx_scope_struct_1_genexpr)))) {
    __pyx_freelist_10denovonear_10transcript___pyx_scope_struct_1_genexpr[__pyx_freecount_10denovonear_10transcript___pyx_scope_struct_1_genexpr++] = ((struct __pyx_obj_10denovonear_10transcript___pyx_scope_struct_1_genexpr *)o);
  } else {
    (*Py_TYPE(o)->tp_free)(o);
  }
}

static int __pyx_tp_traverse_10denovonear_10transcript___pyx_scope_struct_1_genexpr(PyObject *o, visitproc v, void *a) {
  int e;
  struct __pyx_obj_10denovonear_10transcript___pyx_scope_struct_1_genexpr *p = (struct __pyx_obj_10denovonear_10transcript___pyx_scope_struct_1_genexpr *)o;
  if (p->__pyx_outer_scope) {
    e = (*v)(((PyObject *)p->__pyx_outer_scope), a); if (e) return e;
  }
  if (p->__pyx_v_x) {
    e = (*v)(p->__pyx_v_x, a); if (e) return e;
  }
  if (p->__pyx_t_0) {
    e = (*v)(p->__pyx_t_0, a); if (e) return e;
  }
  return 0;
}

static int __pyx_tp_clear_10denovonear_10transcript___pyx_scope_struct_1_genexpr(PyObject *o) {
  PyObject* tmp;
  struct __pyx_obj_10denovonear_10transcript___pyx_scope_struct_1_genexpr *p = (struct __pyx_obj_10denovonear_10transcript___pyx_scope_struct_1_genexpr *)o;
  tmp = ((PyObject*)p->__pyx_outer_scope);
  p->__pyx_outer_scope = ((struct __pyx_obj_10denovonear_10transcript___pyx_scope_struct__insert_region *)Py_None); Py_INCREF(Py_None);
  Py_XDECREF(tmp);
  tmp = ((PyObject*)p->__pyx_v_x);
  p->__pyx_v_x = Py_None; Py_INCREF(Py_None);
  Py_XDECREF(tmp);
  tmp = ((PyObject*)p->__pyx_t_0);
  p->__pyx_t_0 = Py_None; Py_INCREF(Py_None);
  Py_XDECREF(tmp);
  return 0;
}

static PyTypeObject __pyx_type_10denovonear_10transcript___pyx_scope_struct_1_genexpr = {
  PyVarObject_HEAD_INIT(0, 0)
  "denovonear.transcript.__pyx_scope_struct_1_genexpr", /*tp_name*/
  sizeof(struct __pyx_obj_10denovonear_10transcript___pyx_scope_struct_1_genexpr), /*tp_basicsize*/
  0, /*tp_itemsize*/
  __pyx_tp_dealloc_10denovonear_10transcript___pyx_scope_struct_1_genexpr, /*tp_dealloc*/
  0, /*tp_print*/
  0, /*tp_getattr*/
  0, /*tp_setattr*/
  #if PY_MAJOR_VERSION < 3
  0, /*tp_compare*/
  #endif
  #if PY_MAJOR_VERSION >= 3
  0, /*tp_as_async*/
  #endif
  0, /*tp_repr*/
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    goto bad;
invalid_keyword:
    PyErr_Format(PyExc_TypeError,
    #if PY_MAJOR_VERSION < 3
        "%.200s() got an unexpected keyword argument '%.200s'",
        function_name, PyString_AsString(key));
    #else
        "%s() got an unexpected keyword argument '%U'",
        function_name, key);
    #endif
bad:
    return -1;
}

/* PyObjectCall */
#if CYTHON_COMPILING_IN_CPYTHON
static CYTHON_INLINE PyObject* __Pyx_PyObject_Call(PyObject *func, PyObject *arg, PyObject *kw) {
    PyObject *result;
    ternaryfunc call = func->ob_type->tp_call;
    if (unlikely(!call))
        return PyObject_Call(func, arg, kw);
    if (unlikely(Py_EnterRecursiveCall((char*)" while calling a Python object")))
        return NULL;
    result = (*call)(func, arg, kw);
    Py_LeaveRecursiveCall();
    if (unlikely(!result) && unlikely(!PyErr_Occurred())) {
        PyErr_SetString(
            PyExc_SystemError,
            "NULL result without error in PyObject_Call");
    }
    return result;
}
#endif

/* UnicodeAsUCS4 */
static CYTHON_INLINE Py_UCS4 __Pyx_PyUnicode_AsPy_UCS4(PyObject* x) {
   Py_ssize_t length;
   #if CYTHON_PEP393_ENABLED
   length = PyUnicode_GET_LENGTH(x);
   if (likely(length == 1)) {
       return PyUnicode_READ_CHAR(x, 0);
   }
   #else
   length = PyUnicode_GET_SIZE(x);
   if (likely(length == 1)) {
       return PyUnicode_AS_UNICODE(x)[0];
   }
   #if Py_UNICODE_SIZE == 2
   else if (PyUnicode_GET_SIZE(x) == 2) {
       Py_UCS4 high_val = PyUnicode_AS_UNICODE(x)[0];
       if (high_val >= 0xD800 && high_val <= 0xDBFF) {
           Py_UCS4 low_val = PyUnicode_AS_UNICODE(x)[1];
           if (low_val >= 0xDC00 && low_val <= 0xDFFF) {
               return 0x10000 + (((high_val & ((1<<10)-1)) << 10) | (low_val & ((1<<10)-1)));
           }
       }
   }
   #endif
   #endif
   PyErr_Format(PyExc_ValueError,
                "only single character unicode strings can be converted to Py_UCS4, "
                "got length %" CYTHON_FORMAT_SSIZE_T "d", length);
   return (Py_UCS4)-1;
}

/* object_ord */
static long __Pyx__PyObject_Ord(PyObject* c) {
    Py_ssize_t size;
    if (PyBytes_Check(c)) {
        size = PyBytes_GET_SIZE(c);
        if (likely(size == 1)) {
            return (unsigned char) PyBytes_AS_STRING(c)[0];
        }
#if PY_MAJOR_VERSION < 3
    } else if (PyUnicode_Check(c)) {
        return (long)__Pyx_PyUnicode_AsPy_UCS4(c);
#endif
#if (!CYTHON_COMPILING_IN_PYPY) || (defined(PyByteArray_AS_STRING) && defined(PyByteArray_GET_SIZE))
    } else if (PyByteArray_Check(c)) {
        size = PyByteArray_GET_SIZE(c);
        if (likely(size == 1)) {
            return (unsigned char) PyByteArray_AS_STRING(c)[0];
        }
#endif
    } else {
        PyErr_Format(PyExc_TypeError,
            "ord() expected string of length 1, but %.200s found", c->ob_type->tp_name);
        return (long)(Py_UCS4)-1;
    }
    PyErr_Format(PyExc_TypeError,
        "ord() expected a character, but string of length %zd found", size);
    return (long)(Py_UCS4)-1;
}

/* PyFunctionFastCall */
#if CYTHON_FAST_PYCALL
#include "frameobject.h"
static PyObject* __Pyx_PyFunction_FastCallNoKw(PyCodeObject *co, PyObject **args, Py_ssize_t na,
                                               PyObject *globals) {
    PyFrameObject *f;
    PyThreadState *tstate = PyThreadState_GET();
    PyObject **fastlocals;
    Py_ssize_t i;
    PyObject *result;
    assert(globals != NULL);
    /* XXX Perhaps we should create a specialized
       PyFrame_New() that doesn't take locals, but does
       take builtins without sanity checking them.
       */
    assert(tstate != NULL);
    f = PyFrame_New(tstate, co, globals, NULL);
    if (f == NULL) {
        return NULL;
    }
    fastlocals = f->f_localsplus;
    for (i = 0; i < na; i++) {
        Py_INCREF(*args);
        fastlocals[i] = *args++;
    }
    result = PyEval_EvalFrameEx(f,0);
    ++tstate->recursion_depth;
    Py_DECREF(f);
    --tstate->recursion_depth;
    return result;
}
#if 1 || PY_VERSION_HEX < 0x030600B1
static PyObject *__Pyx_PyFunction_FastCallDict(PyObject *func, PyObject **args, int nargs, PyObject *kwargs) {
    PyCodeObject *co = (PyCodeObject *)PyFunction_GET_CODE(func);
    PyObject *globals = PyFunction_GET_GLOBALS(func);
    PyObject *argdefs = PyFunction_GET_DEFAULTS(func);
    PyObject *closure;
#if PY_MAJOR_VERSION >= 3
    PyObject *kwdefs;
#endif
    PyObject *kwtuple, **k;
    PyObject **d;
    Py_ssize_t nd;
    Py_ssize_t nk;
    PyObject *result;
    assert(kwargs == NULL || PyDict_Check(kwargs));
    nk = kwargs ? PyDict_Size(kwargs) : 0;
    if (Py_EnterRecursiveCall((char*)" while calling a Python object")) {
        return NULL;
    }
    if (
#if PY_MAJOR_VERSION >= 3
            co->co_kwonlyargcount == 0 &&
#endif
            likely(kwargs == NULL || nk == 0) &&
            co->co_flags == (CO_OPTIMIZED | CO_NEWLOCALS | CO_NOFREE)) {
        if (argdefs == NULL && co->co_argcount == nargs) {
            result = __Pyx_PyFunction_FastCallNoKw(co, args, nargs, globals);
            goto done;
        }
        else if (nargs == 0 && argdefs != NULL
                 && co->co_argcount == Py_SIZE(argdefs)) {
            /* function called with no arguments, but all parameters have
               a default value: use default values as arguments .*/
            args = &PyTuple_GET_ITEM(argdefs, 0);
            result =__Pyx_PyFunction_FastCallNoKw(co, args, Py_SIZE(argdefs), globals);
            goto done;
        }
    }
    if (kwargs != NULL) {
        Py_ssize_t pos, i;
        kwtuple = PyTuple_New(2 * nk);
        if (kwtuple == NULL) {
            result = NULL;
            goto done;
        }
        k = &PyTuple_GET_ITEM(kwtuple, 0);
        pos = i = 0;
        while (PyDict_Next(kwargs, &pos, &k[i], &k[i+1])) {
            Py_INCREF(k[i]);
            Py_INCREF(k[i+1]);
            i += 2;
        }
        nk = i / 2;
    }
    else {
        kwtuple = NULL;
        k = NULL;
    }
    closure = PyFunction_GET_CLOSURE(func);
#if PY_MAJOR_VERSION >= 3
    kwdefs = PyFunction_GET_KW_DEFAULTS(func);
#endif
    if (argdefs != NULL) {
        d = &PyTuple_GET_ITEM(argdefs, 0);
        nd = Py_SIZE(argdefs);
    }
    else {
        d = NULL;
        nd = 0;
    }
#if PY_MAJOR_VERSION >= 3
    result = PyEval_EvalCodeEx((PyObject*)co, globals, (PyObject *)NULL,
                               args, nargs,
                               k, (int)nk,
                               d, (int)nd, kwdefs, closure);
#else
    result = PyEval_EvalCodeEx(co, globals, (PyObject *)NULL,
                               args, nargs,
                               k, (int)nk,
                               d, (int)nd, closure);
#endif
    Py_XDECREF(kwtuple);
done:
    Py_LeaveRecursiveCall();
    return result;
}
#endif
#endif

/* PyCFunctionFastCall */
#if CYTHON_FAST_PYCCALL
static CYTHON_INLINE PyObject * __Pyx_PyCFunction_FastCall(PyObject *func_obj, PyObject **args, Py_ssize_t nargs) {
    PyCFunctionObject *func = (PyCFunctionObject*)func_obj;
    PyCFunction meth = PyCFunction_GET_FUNCTION(func);
    PyObject *self = PyCFunction_GET_SELF(func);
    int flags = PyCFunction_GET_FLAGS(func);
    assert(PyCFunction_Check(func));
    assert(METH_FASTCALL == (flags & ~(METH_CLASS | METH_STATIC | METH_COEXIST | METH_KEYWORDS)));
    assert(nargs >= 0);
    assert(nargs == 0 || args != NULL);
    /* _PyCFunction_FastCallDict() must not be called with an exception set,
       because it may clear it (directly or indirectly) and so the
       caller loses its exception */
    assert(!PyErr_Occurred());
    if ((PY_VERSION_HEX < 0x030700A0) || unlikely(flags & METH_KEYWORDS)) {
        return (*((__Pyx_PyCFunctionFastWithKeywords)meth)) (self, args, nargs, NULL);
    } else {
        return (*((__Pyx_PyCFunctionFast)meth)) (self, args, nargs);
    }
}
#endif

/* PyObjectCallMethO */
#if CYTHON_COMPILING_IN_CPYTHON
static CYTHON_INLINE PyObject* __Pyx_PyObject_CallMethO(PyObject *func, PyObject *arg) {
    PyObject *self, *result;
    PyCFunction cfunc;
    cfunc = PyCFunction_GET_FUNCTION(func);
    self = PyCFunction_GET_SELF(func);
    if (unlikely(Py_EnterRecursiveCall((char*)" while calling a Python object")))
        return NULL;
    result = cfunc(self, arg);
    Py_LeaveRecursiveCall();
    if (unlikely(!result) && unlikely(!PyErr_Occurred())) {
        PyErr_SetString(
            PyExc_SystemError,
            "NULL result without error in PyObject_Call");
    }
    return result;
}
#endif

/* PyObjectCallOneArg */
#if CYTHON_COMPILING_IN_CPYTHON
static PyObject* __Pyx__PyObject_CallOneArg(PyObject *func, PyObject *arg) {
    PyObject *result;
    PyObject *args = PyTuple_New(1);
    if (unlikely(!args)) return NULL;
    Py_INCREF(arg);
    PyTuple_SET_ITEM(args, 0, arg);
    result = __Pyx_PyObject_Call(func, args, NULL);
    Py_DECREF(args);
    return result;
}
static CYTHON_INLINE PyObject* __Pyx_PyObject_CallOneArg(PyObject *func, PyObject *arg) {
#if CYTHON_FAST_PYCALL
    if (PyFunction_Check(func)) {
        return __Pyx_PyFunction_FastCall(func, &arg, 1);
    }
#endif
    if (likely(PyCFunction_Check(func))) {
        if (likely(PyCFunction_GET_FLAGS(func) & METH_O)) {
            return __Pyx_PyObject_CallMethO(func, arg);
#if CYTHON_FAST_PYCCALL
        } else if (PyCFunction_GET_FLAGS(func) & METH_FASTCALL) {
            return __Pyx_PyCFunction_FastCall(func, &arg, 1);
#endif
        }
    }
    return __Pyx__PyObject_CallOneArg(func, arg);
}
#else
static CYTHON_INLINE PyObject* __Pyx_PyObject_CallOneArg(PyObject *func, PyObject *arg) {
    PyObject *result;
    PyObject *args = PyTuple_Pack(1, arg);
    if (unlikely(!args)) return NULL;
    result = __Pyx_PyObject_Call(func, args, NULL);
    Py_DECREF(args);
    return result;
}
#endif

/* PyObjectCallNoArg */
#if CYTHON_COMPILING_IN_CPYTHON
static CYTHON_INLINE PyObject* __Pyx_PyObject_CallNoArg(PyObject *func) {
#if CYTHON_FAST_PYCALL
    if (PyFunction_Check(func)) {
        return __Pyx_PyFunction_FastCall(func, NULL, 0);
    }
#endif
#ifdef __Pyx_CyFunction_USED
    if (likely(PyCFunction_Check(func) || PyObject_TypeCheck(func, __pyx_CyFunctionType))) {
#else
    if (likely(PyCFunction_Check(func))) {
#endif
        if (likely(PyCFunction_GET_FLAGS(func) & METH_NOARGS)) {
            return __Pyx_PyObject_CallMethO(func, NULL);
        }
    }
    return __Pyx_PyObject_Call(func, __pyx_empty_tuple, NULL);
}
#endif

/* SliceObject */
  static CYTHON_INLINE PyObject* __Pyx_PyObject_GetSlice(PyObject* obj,
        Py_ssize_t cstart, Py_ssize_t cstop,
        PyObject** _py_start, PyObject** _py_stop, PyObject** _py_slice,
        int has_cstart, int has_cstop, CYTHON_UNUSED int wraparound) {
#if CYTHON_USE_TYPE_SLOTS
    PyMappingMethods* mp;
#if PY_MAJOR_VERSION < 3
    PySequenceMethods* ms = Py_TYPE(obj)->tp_as_sequence;
    if (likely(ms && ms->sq_slice)) {
        if (!has_cstart) {
            if (_py_start && (*_py_start != Py_None)) {
                cstart = __Pyx_PyIndex_AsSsize_t(*_py_start);
                if ((cstart == (Py_ssize_t)-1) && PyErr_Occurred()) goto bad;
            } else
                cstart = 0;
        }
        if (!has_cstop) {
            if (_py_stop && (*_py_stop != Py_None)) {
                cstop = __Pyx_PyIndex_AsSsize_t(*_py_stop);
                if ((cstop == (Py_ssize_t)-1) && PyErr_Occurred()) goto bad;
            } else
                cstop = PY_SSIZE_T_MAX;
        }
        if (wraparound && unlikely((cstart < 0) | (cstop < 0)) && likely(ms->sq_length)) {
            Py_ssize_t l = ms->sq_length(obj);
            if (likely(l >= 0)) {
                if (cstop < 0) {
                    cstop += l;
                    if (cstop < 0) cstop = 0;
                }
                if (cstart < 0) {
                    cstart += l;
                    if (cstart < 0) cstart = 0;
                }
            } else {
                if (!PyErr_ExceptionMatches(PyExc_OverflowError))
                    goto bad;
                PyErr_Clear();
            }
        }
        return ms->sq_slice(obj, cstart, cstop);
    }
#endif
    mp = Py_TYPE(obj)->tp_as_mapping;
    if (likely(mp && mp->mp_subscript))
#endif
    {
        PyObject* result;
        PyObject *py_slice, *py_start, *py_stop;
        if (_py_slice) {
            py_slice = *_py_slice;
        } else {
            PyObject* owned_start = NULL;
            PyObject* owned_stop = NULL;
            if (_py_start) {
                py_start = *_py_start;
            } else {
                if (has_cstart) {
                    owned_start = py_start = PyInt_FromSsize_t(cstart);
                    if (unlikely(!py_start)) goto bad;
                } else
                    py_start = Py_None;
            }
            if (_py_stop) {
                py_stop = *_py_stop;
            } else {
                if (has_cstop) {
                    owned_stop = py_stop = PyInt_FromSsize_t(cstop);
                    if (unlikely(!py_stop)) {
                        Py_XDECREF(owned_start);
                        goto bad;
                    }
                } else
                    py_stop = Py_None;
            }
            py_slice = PySlice_New(py_start, py_stop, Py_None);
            Py_XDECREF(owned_start);
            Py_XDECREF(owned_stop);
            if (unlikely(!py_slice)) goto bad;
        }
#if CYTHON_USE_TYPE_SLOTS
        result = mp->mp_subscript(obj, py_slice);
#else
        result = PyObject_GetItem(obj, py_slice);
#endif
        if (!_py_slice) {
            Py_DECREF(py_slice);
        }
        return result;
    }
    PyErr_Format(PyExc_TypeError,
        "'%.200s' object is unsliceable", Py_TYPE(obj)->tp_name);
bad:
    return NULL;
}

/* BytesEquals */
  static CYTHON_INLINE int __Pyx_PyBytes_Equals(PyObject* s1, PyObject* s2, int equals) {
#if CYTHON_COMPILING_IN_PYPY
    return PyObject_RichCompareBool(s1, s2, equals);
#else
    if (s1 == s2) {
        return (equals == Py_EQ);
    } else if (PyBytes_CheckExact(s1) & PyBytes_CheckExact(s2)) {
        const char *ps1, *ps2;
        Py_ssize_t length = PyBytes_GET_SIZE(s1);
        if (length != PyBytes_GET_SIZE(s2))
            return (equals == Py_NE);
        ps1 = PyBytes_AS_STRING(s1);
        ps2 = PyBytes_AS_STRING(s2);
        if (ps1[0] != ps2[0]) {
            return (equals == Py_NE);
        } else if (length == 1) {
            return (equals == Py_EQ);
        } else {
            int result;
#if CYTHON_USE_UNICODE_INTERNALS
            Py_hash_t hash1, hash2;
            hash1 = ((PyBytesObject*)s1)->ob_shash;
            hash2 = ((PyBytesObject*)s2)->ob_shash;
            if (hash1 != hash2 && hash1 != -1 && hash2 != -1) {
                return (equals == Py_NE);
            }
#endif
            result = memcmp(ps1, ps2, (size_t)length);
            return (equals == Py_EQ) ? (result == 0) : (result != 0);
        }
    } else if ((s1 == Py_None) & PyBytes_CheckExact(s2)) {
        return (equals == Py_NE);
    } else if ((s2 == Py_None) & PyBytes_CheckExact(s1)) {
        return (equals == Py_NE);
    } else {
        int result;
        PyObject* py_result = PyObject_RichCompare(s1, s2, equals);
        if (!py_result)
            return -1;
        result = __Pyx_PyObject_IsTrue(py_result);
        Py_DECREF(py_result);
        return result;
    }
#endif
}

/* UnicodeEquals */
  static CYTHON_INLINE int __Pyx_PyUnicode_Equals(PyObject* s1, PyObject* s2, int equals) {
#if CYTHON_COMPILING_IN_PYPY
    return PyObject_RichCompareBool(s1, s2, equals);
#else
#if PY_MAJOR_VERSION < 3
    PyObject* owned_ref = NULL;
#endif
    int s1_is_unicode, s2_is_unicode;
    if (s1 == s2) {
        goto return_eq;
    }
    s1_is_unicode = PyUnicode_CheckExact(s1);
    s2_is_unicode = PyUnicode_CheckExact(s2);
#if PY_MAJOR_VERSION < 3
    if ((s1_is_unicode & (!s2_is_unicode)) && PyString_CheckExact(s2)) {
        owned_ref = PyUnicode_FromObject(s2);
        if (unlikely(!owned_ref))
            return -1;
        s2 = owned_ref;
        s2_is_unicode = 1;
    } else if ((s2_is_unicode & (!s1_is_unicode)) && PyString_CheckExact(s1)) {
        owned_ref = PyUnicode_FromObject(s1);
        if (unlikely(!owned_ref))
            return -1;
        s1 = owned_ref;
        s1_is_unicode = 1;
    } else if (((!s2_is_unicode) & (!s1_is_unicode))) {
        return __Pyx_PyBytes_Equals(s1, s2, equals);
    }
#endif
    if (s1_is_unicode & s2_is_unicode) {
        Py_ssize_t length;
        int kind;
        void *data1, *data2;
        if (unlikely(__Pyx_PyUnicode_READY(s1) < 0) || unlikely(__Pyx_PyUnicode_READY(s2) < 0))
            return -1;
        length = __Pyx_PyUnicode_GET_LENGTH(s1);
        if (length != __Pyx_PyUnicode_GET_LENGTH(s2)) {
            goto return_ne;
        }
#if CYTHON_USE_UNICODE_INTERNALS
        {
            Py_hash_t hash1, hash2;
        #if CYTHON_PEP393_ENABLED
            hash1 = ((PyASCIIObject*)s1)->hash;
            hash2 = ((PyASCIIObject*)s2)->hash;
        #else
            hash1 = ((PyUnicodeObject*)s1)->hash;
            hash2 = ((PyUnicodeObject*)s2)->hash;
        #endif
            if (hash1 != hash2 && hash1 != -1 && hash2 != -1) {
                goto return_ne;
            }
        }
#endif
        kind = __Pyx_PyUnicode_KIND(s1);
        if (kind != __Pyx_PyUnicode_KIND(s2)) {
            goto return_ne;
        }
        data1 = __Pyx_PyUnicode_DATA(s1);
        data2 = __Pyx_PyUnicode_DATA(s2);
        if (__Pyx_PyUnicode_READ(kind, data1, 0) != __Pyx_PyUnicode_READ(kind, data2, 0)) {
            goto return_ne;
        } else if (length == 1) {
            goto return_eq;
        } else {
            int result = memcmp(data1, data2, (size_t)(length * kind));
            #if PY_MAJOR_VERSION < 3
            Py_XDECREF(owned_ref);
            #endif
            return (equals == Py_EQ) ? (result == 0) : (result != 0);
        }
    } else if ((s1 == Py_None) & s2_is_unicode) {
        goto return_ne;
    } else if ((s2 == Py_None) & s1_is_unicode) {
        goto return_ne;
    } else {
        int result;
        PyObject* py_result = PyObject_RichCompare(s1, s2, equals);
        if (!py_result)
            return -1;
        result = __Pyx_PyObject_IsTrue(py_result);
        Py_DECREF(py_result);
        return result;
    }
return_eq:
    #if PY_MAJOR_VERSION < 3
    Py_XDECREF(owned_ref);
    #endif
    return (equals == Py_EQ);
return_ne:
    #if PY_MAJOR_VERSION < 3
    Py_XDECREF(owned_ref);
    #endif
    return (equals == Py_NE);
#endif
}

/* PyIntBinop */
  #if !CYTHON_COMPILING_IN_PYPY
static PyObject* __Pyx_PyInt_EqObjC(PyObject *op1, PyObject *op2, CYTHON_UNUSED long intval, CYTHON_UNUSED int inplace) {
    if (op1 == op2) {
        Py_RETURN_TRUE;
    }
    #if PY_MAJOR_VERSION < 3
    if (likely(PyInt_CheckExact(op1))) {
        const long b = intval;
        long a = PyInt_AS_LONG(op1);
        if (a == b) {
            Py_RETURN_TRUE;
        } else {
            Py_RETURN_FALSE;
        }
    }
    #endif
    #if CYTHON_USE_PYLONG_INTERNALS
    if (likely(PyLong_CheckExact(op1))) {
        const long b = intval;
        long a;
        const digit* digits = ((PyLongObject*)op1)->ob_digit;
        const Py_ssize_t size = Py_SIZE(op1);
        if (likely(__Pyx_sst_abs(size) <= 1)) {
            a = likely(size) ? digits[0] : 0;
            if (size == -1) a = -a;
        } else {
            switch (size) {
                case -2:
                    if (8 * sizeof(long) - 1 > 2 * PyLong_SHIFT) {
                        a = -(long) (((((unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0]));
                        break;
                    }
                case 2:
                    if (8 * sizeof(long) - 1 > 2 * PyLong_SHIFT) {
                        a = (long) (((((unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0]));
                        break;
                    }
                case -3:
                    if (8 * sizeof(long) - 1 > 3 * PyLong_SHIFT) {
                        a = -(long) (((((((unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0]));
                        break;
                    }
                case 3:
                    if (8 * sizeof(long) - 1 > 3 * PyLong_SHIFT) {
                        a = (long) (((((((unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0]));
                        break;
                    }
                case -4:
                    if (8 * sizeof(long) - 1 > 4 * PyLong_SHIFT) {
                        a = -(long) (((((((((unsigned long)digits[3]) << PyLong_SHIFT) | (unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0]));
                        break;
                    }
                case 4:
                    if (8 * sizeof(long) - 1 > 4 * PyLong_SHIFT) {
                        a = (long) (((((((((unsigned long)digits[3]) << PyLong_SHIFT) | (unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0]));
                        break;
                    }
                #if PyLong_SHIFT < 30 && PyLong_SHIFT != 15
                default: return PyLong_Type.tp_richcompare(op1, op2, Py_EQ);
                #else
                default: Py_RETURN_FALSE;
                #endif
            }
        }
            if (a == b) {
                Py_RETURN_TRUE;
            } else {
                Py_RETURN_FALSE;
            }
    }
    #endif
    if (PyFloat_CheckExact(op1)) {
        const long b = intval;
        double a = PyFloat_AS_DOUBLE(op1);
            if ((double)a == (double)b) {
                Py_RETURN_TRUE;
            } else {
                Py_RETURN_FALSE;
            }
    }
    return PyObject_RichCompare(op1, op2, Py_EQ);
}
#endif

/* PyErrFetchRestore */
  #if CYTHON_FAST_THREAD_STATE
static CYTHON_INLINE void __Pyx_ErrRestoreInState(PyThreadState *tstate, PyObject *type, PyObject *value, PyObject *tb) {
    PyObject *tmp_type, *tmp_value, *tmp_tb;
    tmp_type = tstate->curexc_type;
    tmp_value = tstate->curexc_value;
    tmp_tb = tstate->curexc_traceback;
    tstate->curexc_type = type;
    tstate->curexc_value = value;
    tstate->curexc_traceback = tb;
    Py_XDECREF(tmp_type);
    Py_XDECREF(tmp_value);
    Py_XDECREF(tmp_tb);
}
static CYTHON_INLINE void __Pyx_ErrFetchInState(PyThreadState *tstate, PyObject **type, PyObject **value, PyObject **tb) {
    *type = tstate->curexc_type;
    *value = tstate->curexc_value;
    *tb = tstate->curexc_traceback;
    tstate->curexc_type = 0;
    tstate->curexc_value = 0;
    tstate->curexc_traceback = 0;
}
#endif

/* RaiseException */
  #if PY_MAJOR_VERSION < 3
static void __Pyx_Raise(PyObject *type, PyObject *value, PyObject *tb,
                        CYTHON_UNUSED PyObject *cause) {
    __Pyx_PyThreadState_declare
    Py_XINCREF(type);
    if (!value || value == Py_None)
        value = NULL;
    else
        Py_INCREF(value);
    if (!tb || tb == Py_None)
        tb = NULL;
    else {
        Py_INCREF(tb);
        if (!PyTraceBack_Check(tb)) {
            PyErr_SetString(PyExc_TypeError,
                "raise: arg 3 must be a traceback or None");
            goto raise_error;
        }
    }
    if (PyType_Check(type)) {
#if CYTHON_COMPILING_IN_PYPY
        if (!value) {
            Py_INCREF(Py_None);
            value = Py_None;
        }
#endif
        PyErr_NormalizeException(&type, &value, &tb);
    } else {
        if (value) {
            PyErr_SetString(PyExc_TypeError,
                "instance exception may not have a separate value");
            goto raise_error;
        }
        value = type;
        type = (PyObject*) Py_TYPE(type);
        Py_INCREF(type);
        if (!PyType_IsSubtype((PyTypeObject *)type, (PyTypeObject *)PyExc_BaseException)) {
            PyErr_SetString(PyExc_TypeError,
                "raise: exception class must be a subclass of BaseException");
            goto raise_error;
        }
    }
    __Pyx_PyThreadState_assign
    __Pyx_ErrRestore(type, value, tb);
    return;
raise_error:
    Py_XDECREF(value);
    Py_XDECREF(type);
    Py_XDECREF(tb);
    return;
}
#else
static void __Pyx_Raise(PyObject *type, PyObject *value, PyObject *tb, PyObject *cause) {
    PyObject* owned_instance = NULL;
    if (tb == Py_None) {
        tb = 0;
    } else if (tb && !PyTraceBack_Check(tb)) {
        PyErr_SetString(PyExc_TypeError,
            "raise: arg 3 must be a traceback or None");
        goto bad;
    }
    if (value == Py_None)
        value = 0;
    if (PyExceptionInstance_Check(type)) {
        if (value) {
            PyErr_SetString(PyExc_TypeError,
                "instance exception may not have a separate value");
            goto bad;
        }
        value = type;
        type = (PyObject*) Py_TYPE(value);
    } else if (PyExceptionClass_Check(type)) {
        PyObject *instance_class = NULL;
        if (value && PyExceptionInstance_Check(value)) {
            instance_class = (PyObject*) Py_TYPE(value);
            if (instance_class != type) {
                int is_subclass = PyObject_IsSubclass(instance_class, type);
                if (!is_subclass) {
                    instance_class = NULL;
                } else if (unlikely(is_subclass == -1)) {
                    goto bad;
                } else {
                    type = instance_class;
                }
            }
        }
        if (!instance_class) {
            PyObject *args;
            if (!value)
                args = PyTuple_New(0);
            else if (PyTuple_Check(value)) {
                Py_INCREF(value);
                args = value;
            } else
                args = PyTuple_Pack(1, value);
            if (!args)
                goto bad;
            owned_instance = PyObject_Call(type, args, NULL);
            Py_DECREF(args);
            if (!owned_instance)
                goto bad;
            value = owned_instance;
            if (!PyExceptionInstance_Check(value)) {
                PyErr_Format(PyExc_TypeError,
                             "calling %R should have returned an instance of "
                             "BaseException, not %R",
                             type, Py_TYPE(value));
                goto bad;
            }
        }
    } else {
        PyErr_SetString(PyExc_TypeError,
            "raise: exception class must be a subclass of BaseException");
        goto bad;
    }
#if PY_VERSION_HEX >= 0x03030000
    if (cause) {
#else
    if (cause && cause != Py_None) {
#endif
        PyObject *fixed_cause;
        if (cause == Py_None) {
            fixed_cause = NULL;
        } else if (PyExceptionClass_Check(cause)) {
            fixed_cause = PyObject_CallObject(cause, NULL);
            if (fixed_cause == NULL)
                goto bad;
        } else if (PyExceptionInstance_Check(cause)) {
            fixed_cause = cause;
            Py_INCREF(fixed_cause);
        } else {
            PyErr_SetString(PyExc_TypeError,
                            "exception causes must derive from "
                            "BaseException");
            goto bad;
        }
        PyException_SetCause(value, fixed_cause);
    }
    PyErr_SetObject(type, value);
    if (tb) {
#if CYTHON_COMPILING_IN_PYPY
        PyObject *tmp_type, *tmp_value, *tmp_tb;
        PyErr_Fetch(&tmp_type, &tmp_value, &tmp_tb);
        Py_INCREF(tb);
        PyErr_Restore(tmp_type, tmp_value, tb);
        Py_XDECREF(tmp_tb);
#else
        PyThreadState *tstate = PyThreadState_GET();
        PyObject* tmp_tb = tstate->curexc_traceback;
        if (tb != tmp_tb) {
            Py_INCREF(tb);
            tstate->curexc_traceback = tb;
            Py_XDECREF(tmp_tb);
        }
#endif
    }
bad:
    Py_XDECREF(owned_instance);
    return;
}
#endif

/* PyIntBinop */
    #if !CYTHON_COMPILING_IN_PYPY
static PyObject* __Pyx_PyInt_AddObjC(PyObject *op1, PyObject *op2, CYTHON_UNUSED long intval, CYTHON_UNUSED int inplace) {
    #if PY_MAJOR_VERSION < 3
    if (likely(PyInt_CheckExact(op1))) {
        const long b = intval;
        long x;
        long a = PyInt_AS_LONG(op1);
            x = (long)((unsigned long)a + b);
            if (likely((x^a) >= 0 || (x^b) >= 0))
                return PyInt_FromLong(x);
            return PyLong_Type.tp_as_number->nb_add(op1, op2);
    }
    #endif
    #if CYTHON_USE_PYLONG_INTERNALS
    if (likely(PyLong_CheckExact(op1))) {
        const long b = intval;
        long a, x;
#ifdef HAVE_LONG_LONG
        const PY_LONG_LONG llb = intval;
        PY_LONG_LONG lla, llx;
#endif
        const digit* digits = ((PyLongObject*)op1)->ob_digit;
        const Py_ssize_t size = Py_SIZE(op1);
        if (likely(__Pyx_sst_abs(size) <= 1)) {
            a = likely(size) ? digits[0] : 0;
            if (size == -1) a = -a;
        } else {
            switch (size) {
                case -2:
                    if (8 * sizeof(long) - 1 > 2 * PyLong_SHIFT) {
                        a = -(long) (((((unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0]));
                        break;
#ifdef HAVE_LONG_LONG
                    } else if (8 * sizeof(PY_LONG_LONG) - 1 > 2 * PyLong_SHIFT) {
                        lla = -(PY_LONG_LONG) (((((unsigned PY_LONG_LONG)digits[1]) << PyLong_SHIFT) | (unsigned PY_LONG_LONG)digits[0]));
                        goto long_long;
#endif
                    }
                case 2:
                    if (8 * sizeof(long) - 1 > 2 * PyLong_SHIFT) {
                        a = (long) (((((unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0]));
                        break;
#ifdef HAVE_LONG_LONG
                    } else if (8 * sizeof(PY_LONG_LONG) - 1 > 2 * PyLong_SHIFT) {
                        lla = (PY_LONG_LONG) (((((unsigned PY_LONG_LONG)digits[1]) << PyLong_SHIFT) | (unsigned PY_LONG_LONG)digits[0]));
                        goto long_long;
#endif
                    }
                case -3:
                    if (8 * sizeof(long) - 1 > 3 * PyLong_SHIFT) {
                        a = -(long) (((((((unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0]));
                        break;
#ifdef HAVE_LONG_LONG
                    } else if (8 * sizeof(PY_LONG_LONG) - 1 > 3 * PyLong_SHIFT) {
                        lla = -(PY_LONG_LONG) (((((((unsigned PY_LONG_LONG)digits[2]) << PyLong_SHIFT) | (unsigned PY_LONG_LONG)digits[1]) << PyLong_SHIFT) | (unsigned PY_LONG_LONG)digits[0]));
                        goto long_long;
#endif
                    }
                case 3:
                    if (8 * sizeof(long) - 1 > 3 * PyLong_SHIFT) {
                        a = (long) (((((((unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0]));
                        break;
#ifdef HAVE_LONG_LONG
                    } else if (8 * sizeof(PY_LONG_LONG) - 1 > 3 * PyLong_SHIFT) {
                        lla = (PY_LONG_LONG) (((((((unsigned PY_LONG_LONG)digits[2]) << PyLong_SHIFT) | (unsigned PY_LONG_LONG)digits[1]) << PyLong_SHIFT) | (unsigned PY_LONG_LONG)digits[0]));
                        goto long_long;
#endif
                    }
                case -4:
                    if (8 * sizeof(long) - 1 > 4 * PyLong_SHIFT) {
                        a = -(long) (((((((((unsigned long)digits[3]) << PyLong_SHIFT) | (unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0]));
                        break;
#ifdef HAVE_LONG_LONG
                    } else if (8 * sizeof(PY_LONG_LONG) - 1 > 4 * PyLong_SHIFT) {
                        lla = -(PY_LONG_LONG) (((((((((unsigned PY_LONG_LONG)digits[3]) << PyLong_SHIFT) | (unsigned PY_LONG_LONG)digits[2]) << PyLong_SHIFT) | (unsigned PY_LONG_LONG)digits[1]) << PyLong_SHIFT) | (unsigned PY_LONG_LONG)digits[0]));
                        goto long_long;
#endif
                    }
                case 4:
                    if (8 * sizeof(long) - 1 > 4 * PyLong_SHIFT) {
                        a = (long) (((((((((unsigned long)digits[3]) << PyLong_SHIFT) | (unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0]));
                        break;
#ifdef HAVE_LONG_LONG
                    } else if (8 * sizeof(PY_LONG_LONG) - 1 > 4 * PyLong_SHIFT) {
                        lla = (PY_LONG_LONG) (((((((((unsigned PY_LONG_LONG)digits[3]) << PyLong_SHIFT) | (unsigned PY_LONG_LONG)digits[2]) << PyLong_SHIFT) | (unsigned PY_LONG_LONG)digits[1]) << PyLong_SHIFT) | (unsigned PY_LONG_LONG)digits[0]));
                        goto long_long;
#endif
                    }
                default: return PyLong_Type.tp_as_number->nb_add(op1, op2);
            }
        }
                x = a + b;
            return PyLong_FromLong(x);
#ifdef HAVE_LONG_LONG
        long_long:
                llx = lla + llb;
            return PyLong_FromLongLong(llx);
#endif
        
        
    }
    #endif
    if (PyFloat_CheckExact(op1)) {
        const long b = intval;
        double a = PyFloat_AS_DOUBLE(op1);
            double result;
            PyFPE_START_PROTECT("add", return NULL)
            result = ((double)a) + (double)b;
            PyFPE_END_PROTECT(result)
            return PyFloat_FromDouble(result);
    }
    return (inplace ? PyNumber_InPlaceAdd : PyNumber_Add)(op1, op2);
}
#endif

/* None */
    static CYTHON_INLINE void __Pyx_RaiseClosureNameError(const char *varname) {
    PyErr_Format(PyExc_NameError, "free variable '%s' referenced before assignment in enclosing scope", varname);
}

/* GetModuleGlobalName */
    static CYTHON_INLINE PyObject *__Pyx_GetModuleGlobalName(PyObject *name) {
    PyObject *result;
#if !CYTHON_AVOID_BORROWED_REFS
    result = PyDict_GetItem(__pyx_d, name);
    if (likely(result)) {
        Py_INCREF(result);
    } else {
#else
    result = PyObject_GetItem(__pyx_d, name);
    if (!result) {
        PyErr_Clear();
#endif
        result = __Pyx_GetBuiltinName(name);
    }
    return result;
}

/* RaiseTooManyValuesToUnpack */
      static CYTHON_INLINE void __Pyx_RaiseTooManyValuesError(Py_ssize_t expected) {
    PyErr_Format(PyExc_ValueError,
                 "too many values to unpack (expected %" CYTHON_FORMAT_SSIZE_T "d)", expected);
}

/* RaiseNeedMoreValuesToUnpack */
      static CYTHON_INLINE void __Pyx_RaiseNeedMoreValuesError(Py_ssize_t index) {
    PyErr_Format(PyExc_ValueError,
                 "need more than %" CYTHON_FORMAT_SSIZE_T "d value%.1s to unpack",
                 index, (index == 1) ? "" : "s");
}

/* IterFinish */
      static CYTHON_INLINE int __Pyx_IterFinish(void) {
#if CYTHON_FAST_THREAD_STATE
    PyThreadState *tstate = PyThreadState_GET();
    PyObject* exc_type = tstate->curexc_type;
    if (unlikely(exc_type)) {
        if (likely(exc_type == PyExc_StopIteration) || PyErr_GivenExceptionMatches(exc_type, PyExc_StopIteration)) {
            PyObject *exc_value, *exc_tb;
            exc_value = tstate->curexc_value;
            exc_tb = tstate->curexc_traceback;
            tstate->curexc_type = 0;
            tstate->curexc_value = 0;
            tstate->curexc_traceback = 0;
            Py_DECREF(exc_type);
            Py_XDECREF(exc_value);
            Py_XDECREF(exc_tb);
            return 0;
        } else {
            return -1;
        }
    }
    return 0;
#else
    if (unlikely(PyErr_Occurred())) {
        if (likely(PyErr_ExceptionMatches(PyExc_StopIteration))) {
            PyErr_Clear();
            return 0;
        } else {
            return -1;
        }
    }
    return 0;
#endif
}

/* UnpackItemEndCheck */
      static int __Pyx_IternextUnpackEndCheck(PyObject *retval, Py_ssize_t expected) {
    if (unlikely(retval)) {
        Py_DECREF(retval);
        __Pyx_RaiseTooManyValuesError(expected);
        return -1;
    } else {
        return __Pyx_IterFinish();
    }
    return 0;
}

/* FetchCommonType */
      static PyTypeObject* __Pyx_FetchCommonType(PyTypeObject* type) {
    PyObject* fake_module;
    PyTypeObject* cached_type = NULL;
    fake_module = PyImport_AddModule((char*) "_cython_" CYTHON_ABI);
    if (!fake_module) return NULL;
    Py_INCREF(fake_module);
    cached_type = (PyTypeObject*) PyObject_GetAttrString(fake_module, type->tp_name);
    if (cached_type) {
        if (!PyType_Check((PyObject*)cached_type)) {
            PyErr_Format(PyExc_TypeError,
                "Shared Cython type %.200s is not a type object",
                type->tp_name);
            goto bad;
        }
        if (cached_type->tp_basicsize != type->tp_basicsize) {
            PyErr_Format(PyExc_TypeError,
                "Shared Cython type %.200s has the wrong size, try recompiling",
                type->tp_name);
            goto bad;
        }
    } else {
        if (!PyErr_ExceptionMatches(PyExc_AttributeError)) goto bad;
        PyErr_Clear();
        if (PyType_Ready(type) < 0) goto bad;
        if (PyObject_SetAttrString(fake_module, type->tp_name, (PyObject*) type) < 0)
            goto bad;
        Py_INCREF(type);
        cached_type = type;
    }
done:
    Py_DECREF(fake_module);
    return cached_type;
bad:
    Py_XDECREF(cached_type);
    cached_type = NULL;
    goto done;
}

/* CythonFunction */
      static PyObject *
__Pyx_CyFunction_get_doc(__pyx_CyFunctionObject *op, CYTHON_UNUSED void *closure)
{
    if (unlikely(op->func_doc == NULL)) {
        if (op->func.m_ml->ml_doc) {
#if PY_MAJOR_VERSION >= 3
            op->func_doc = PyUnicode_FromString(op->func.m_ml->ml_doc);
#else
            op->func_doc = PyString_FromString(op->func.m_ml->ml_doc);
#endif
            if (unlikely(op->func_doc == NULL))
                return NULL;
        } else {
            Py_INCREF(Py_None);
            return Py_None;
        }
    }
    Py_INCREF(op->func_doc);
    return op->func_doc;
}
static int
__Pyx_CyFunction_set_doc(__pyx_CyFunctionObject *op, PyObject *value)
{
    PyObject *tmp = op->func_doc;
    if (value == NULL) {
        value = Py_None;
    }
    Py_INCREF(value);
    op->func_doc = value;
    Py_XDECREF(tmp);
    return 0;
}
static PyObject *
__Pyx_CyFunction_get_name(__pyx_CyFunctionObject *op)
{
    if (unlikely(op->func_name == NULL)) {
#if PY_MAJOR_VERSION >= 3
        op->func_name = PyUnicode_InternFromString(op->func.m_ml->ml_name);
#else
        op->func_name = PyString_InternFromString(op->func.m_ml->ml_name);
#endif
        if (unlikely(op->func_name == NULL))
            return NULL;
    }
    Py_INCREF(op->func_name);
    return op->func_name;
}
static int
__Pyx_CyFunction_set_name(__pyx_CyFunctionObject *op, PyObject *value)
{
    PyObject *tmp;
#if PY_MAJOR_VERSION >= 3
    if (unlikely(value == NULL || !PyUnicode_Check(value))) {
#else
    if (unlikely(value == NULL || !PyString_Check(value))) {
#endif
        PyErr_SetString(PyExc_TypeError,
                        "__name__ must be set to a string object");
        return -1;
    }
    tmp = op->func_name;
    Py_INCREF(value);
    op->func_name = value;
    Py_XDECREF(tmp);
    return 0;
}
static PyObject *
__Pyx_CyFunction_get_qualname(__pyx_CyFunctionObject *op)
{
    Py_INCREF(op->func_qualname);
    return op->func_qualname;
}
static int
__Pyx_CyFunction_set_qualname(__pyx_CyFunctionObject *op, PyObject *value)
{
    PyObject *tmp;
#if PY_MAJOR_VERSION >= 3
    if (unlikely(value == NULL || !PyUnicode_Check(value))) {
#else
    if (unlikely(value == NULL || !PyString_Check(value))) {
#endif
        PyErr_SetString(PyExc_TypeError,
                        "__qualname__ must be set to a string object");
        return -1;
    }
    tmp = op->func_qualname;
    Py_INCREF(value);
    op->func_qualname = value;
    Py_XDECREF(tmp);
    return 0;
}
static PyObject *
__Pyx_CyFunction_get_self(__pyx_CyFunctionObject *m, CYTHON_UNUSED void *closure)
{
    PyObject *self;
    self = m->func_closure;
    if (self == NULL)
        self = Py_None;
    Py_INCREF(self);
    return self;
}
static PyObject *
__Pyx_CyFunction_get_dict(__pyx_CyFunctionObject *op)
{
    if (unlikely(op->func_dict == NULL)) {
        op->func_dict = PyDict_New();
        if (unlikely(op->func_dict == NULL))
            return NULL;
    }
    Py_INCREF(op->func_dict);
    return op->func_dict;
}
static int
__Pyx_CyFunction_set_dict(__pyx_CyFunctionObject *op, PyObject *value)
{
    PyObject *tmp;
    if (unlikely(value == NULL)) {
        PyErr_SetString(PyExc_TypeError,
               "function's dictionary may not be deleted");
        return -1;
    }
    if (unlikely(!PyDict_Check(value))) {
        PyErr_SetString(PyExc_TypeError,
               "setting function's dictionary to a non-dict");
        return -1;
    }
    tmp = op->func_dict;
    Py_INCREF(value);
    op->func_dict = value;
    Py_XDECREF(tmp);
    return 0;
}
static PyObject *
__Pyx_CyFunction_get_globals(__pyx_CyFunctionObject *op)
{
    Py_INCREF(op->func_globals);
    return op->func_globals;
}
static PyObject *
__Pyx_CyFunction_get_closure(CYTHON_UNUSED __pyx_CyFunctionObject *op)
{
    Py_INCREF(Py_None);
    return Py_None;
}
static PyObject *
__Pyx_CyFunction_get_code(__pyx_CyFunctionObject *op)
{
    PyObject* result = (op->func_code) ? op->func_code : Py_None;
    Py_INCREF(result);
    return result;
}
static int
__Pyx_CyFunction_init_defaults(__pyx_CyFunctionObject *op) {
    int result = 0;
    PyObject *res = op->defaults_getter((PyObject *) op);
    if (unlikely(!res))
        return -1;
    #if CYTHON_ASSUME_SAFE_MACROS && !CYTHON_AVOID_BORROWED_REFS
    op->defaults_tuple = PyTuple_GET_ITEM(res, 0);
    Py_INCREF(op->defaults_tuple);
    op->defaults_kwdict = PyTuple_GET_ITEM(res, 1);
    Py_INCREF(op->defaults_kwdict);
    #else
    op->defaults_tuple = PySequence_ITEM(res, 0);
    if (unlikely(!op->defaults_tuple)) result = -1;
    else {
        op->defaults_kwdict = PySequence_ITEM(res, 1);
        if (unlikely(!op->defaults_kwdict)) result = -1;
    }
    #endif
    Py_DECREF(res);
    return result;
}
static int
__Pyx_CyFunction_set_defaults(__pyx_CyFunctionObject *op, PyObject* value) {
    PyObject* tmp;
    if (!value) {
        value = Py_None;
    } else if (value != Py_None && !PyTuple_Check(value)) {
        PyErr_SetString(PyExc_TypeError,
                        "__defaults__ must be set to a tuple object");
        return -1;
    }
    Py_INCREF(value);
    tmp = op->defaults_tuple;
    op->defaults_tuple = value;
    Py_XDECREF(tmp);
    return 0;
}
static PyObject *
__Pyx_CyFunction_get_defaults(__pyx_CyFunctionObject *op) {
    PyObject* result = op->defaults_tuple;
    if (unlikely(!result)) {
        if (op->defaults_getter) {
            if (__Pyx_CyFunction_init_defaults(op) < 0) return NULL;
            result = op->defaults_tuple;
        } else {
            result = Py_None;
        }
    }
    Py_INCREF(result);
    return result;
}
static int
__Pyx_CyFunction_set_kwdefaults(__pyx_CyFunctionObject *op, PyObject* value) {
    PyObject* tmp;
    if (!value) {
        value = Py_None;
    } else if (value != Py_None && !PyDict_Check(value)) {
        PyErr_SetString(PyExc_TypeError,
                        "__kwdefaults__ must be set to a dict object");
        return -1;
    }
    Py_INCREF(value);
    tmp = op->defaults_kwdict;
    op->defaults_kwdict = value;
    Py_XDECREF(tmp);
    return 0;
}
static PyObject *
__Pyx_CyFunction_get_kwdefaults(__pyx_CyFunctionObject *op) {
    PyObject* result = op->defaults_kwdict;
    if (unlikely(!result)) {
        if (op->defaults_getter) {
            if (__Pyx_CyFunction_init_defaults(op) < 0) return NULL;
            result = op->defaults_kwdict;
        } else {
            result = Py_None;
        }
    }
    Py_INCREF(result);
    return result;
}
static int
__Pyx_CyFunction_set_annotations(__pyx_CyFunctionObject *op, PyObject* value) {
    PyObject* tmp;
    if (!value || value == Py_None) {
        value = NULL;
    } else if (!PyDict_Check(value)) {
        PyErr_SetString(PyExc_TypeError,
                        "__annotations__ must be set to a dict object");
        return -1;
    }
    Py_XINCREF(value);
    tmp = op->func_annotations;
    op->func_annotations = value;
    Py_XDECREF(tmp);
    return 0;
}
static PyObject *
__Pyx_CyFunction_get_annotations(__pyx_CyFunctionObject *op) {
    PyObject* result = op->func_annotations;
    if (unlikely(!result)) {
        result = PyDict_New();
        if (unlikely(!result)) return NULL;
        op->func_annotations = result;
    }
    Py_INCREF(result);
    return result;
}
static PyGetSetDef __pyx_CyFunction_getsets[] = {
    {(char *) "func_doc", (getter)__Pyx_CyFunction_get_doc, (setter)__Pyx_CyFunction_set_doc, 0, 0},
    {(char *) "__doc__",  (getter)__Pyx_CyFunction_get_doc, (setter)__Pyx_CyFunction_set_doc, 0, 0},
    {(char *) "func_name", (getter)__Pyx_CyFunction_get_name, (setter)__Pyx_CyFunction_set_name, 0, 0},
    {(char *) "__name__", (getter)__Pyx_CyFunction_get_name, (setter)__Pyx_CyFunction_set_name, 0, 0},
    {(char *) "__qualname__", (getter)__Pyx_CyFunction_get_qualname, (setter)__Pyx_CyFunction_set_qualname, 0, 0},
    {(char *) "__self__", (getter)__Pyx_CyFunction_get_self, 0, 0, 0},
    {(char *) "func_dict", (getter)__Pyx_CyFunction_get_dict, (setter)__Pyx_CyFunction_set_dict, 0, 0},
    {(char *) "__dict__", (getter)__Pyx_CyFunction_get_dict, (setter)__Pyx_CyFunction_set_dict, 0, 0},
    {(char *) "func_globals", (getter)__Pyx_CyFunction_get_globals, 0, 0, 0},
    {(char *) "__globals__", (getter)__Pyx_CyFunction_get_globals, 0, 0, 0},
    {(char *) "func_closure", (getter)__Pyx_CyFunction_get_closure, 0, 0, 0},
    {(char *) "__closure__", (getter)__Pyx_CyFunction_get_closure, 0, 0, 0},
    {(char *) "func_code", (getter)__Pyx_CyFunction_get_code, 0, 0, 0},
    {(char *) "__code__", (getter)__Pyx_CyFunction_get_code, 0, 0, 0},
    {(char *) "func_defaults", (getter)__Pyx_CyFunction_get_defaults, (setter)__Pyx_CyFunction_set_defaults, 0, 0},
    {(char *) "__defaults__", (getter)__Pyx_CyFunction_get_defaults, (setter)__Pyx_CyFunction_set_defaults, 0, 0},
    {(char *) "__kwdefaults__", (getter)__Pyx_CyFunction_get_kwdefaults, (setter)__Pyx_CyFunction_set_kwdefaults, 0, 0},
    {(char *) "__annotations__", (getter)__Pyx_CyFunction_get_annotations, (setter)__Pyx_CyFunction_set_annotations, 0, 0},
    {0, 0, 0, 0, 0}
};
static PyMemberDef __pyx_CyFunction_members[] = {
    {(char *) "__module__", T_OBJECT, offsetof(__pyx_CyFunctionObject, func.m_module), PY_WRITE_RESTRICTED, 0},
    {0, 0, 0,  0, 0}
};
static PyObject *
__Pyx_CyFunction_reduce(__pyx_CyFunctionObject *m, CYTHON_UNUSED PyObject *args)
{
#if PY_MAJOR_VERSION >= 3
    return PyUnicode_FromString(m->func.m_ml->ml_name);
#else
    return PyString_FromString(m->func.m_ml->ml_name);
#endif
}
static PyMethodDef __pyx_CyFunction_methods[] = {
    {"__reduce__", (PyCFunction)__Pyx_CyFunction_reduce, METH_VARARGS, 0},
    {0, 0, 0, 0}
};
#if PY_VERSION_HEX < 0x030500A0
#define __Pyx_CyFunction_weakreflist(cyfunc) ((cyfunc)->func_weakreflist)
#else
#define __Pyx_CyFunction_weakreflist(cyfunc) ((cyfunc)->func.m_weakreflist)
#endif
static PyObject *__Pyx_CyFunction_New(PyTypeObject *type, PyMethodDef *ml, int flags, PyObject* qualname,
                                      PyObject *closure, PyObject *module, PyObject* globals, PyObject* code) {
    __pyx_CyFunctionObject *op = PyObject_GC_New(__pyx_CyFunctionObject, type);
    if (op == NULL)
        return NULL;
    op->flags = flags;
    __Pyx_CyFunction_weakreflist(op) = NULL;
    op->func.m_ml = ml;
    op->func.m_self = (PyObject *) op;
    Py_XINCREF(closure);
    op->func_closure = closure;
    Py_XINCREF(module);
    op->func.m_module = module;
    op->func_dict = NULL;
    op->func_name = NULL;
    Py_INCREF(qualname);
    op->func_qualname = qualname;
    op->func_doc = NULL;
    op->func_classobj = NULL;
    op->func_globals = globals;
    Py_INCREF(op->func_globals);
    Py_XINCREF(code);
    op->func_code = code;
    op->defaults_pyobjects = 0;
    op->defaults = NULL;
    op->defaults_tuple = NULL;
    op->defaults_kwdict = NULL;
    op->defaults_getter = NULL;
    op->func_annotations = NULL;
    PyObject_GC_Track(op);
    return (PyObject *) op;
}
static int
__Pyx_CyFunction_clear(__pyx_CyFunctionObject *m)
{
    Py_CLEAR(m->func_closure);
    Py_CLEAR(m->func.m_module);
    Py_CLEAR(m->func_dict);
    Py_CLEAR(m->func_name);
    Py_CLEAR(m->func_qualname);
    Py_CLEAR(m->func_doc);
    Py_CLEAR(m->func_globals);
    Py_CLEAR(m->func_code);
    Py_CLEAR(m->func_classobj);
    Py_CLEAR(m->defaults_tuple);
    Py_CLEAR(m->defaults_kwdict);
    Py_CLEAR(m->func_annotations);
    if (m->defaults) {
        PyObject **pydefaults = __Pyx_CyFunction_Defaults(PyObject *, m);
        int i;
        for (i = 0; i < m->defaults_pyobjects; i++)
            Py_XDECREF(pydefaults[i]);
        PyObject_Free(m->defaults);
        m->defaults = NULL;
    }
    return 0;
}
static void __Pyx_CyFunction_dealloc(__pyx_CyFunctionObject *m)
{
    PyObject_GC_UnTrack(m);
    if (__Pyx_CyFunction_weakreflist(m) != NULL)
        PyObject_ClearWeakRefs((PyObject *) m);
    __Pyx_CyFunction_clear(m);
    PyObject_GC_Del(m);
}
static int __Pyx_CyFunction_traverse(__pyx_CyFunctionObject *m, visitproc visit, void *arg)
{
    Py_VISIT(m->func_closure);
    Py_VISIT(m->func.m_module);
    Py_VISIT(m->func_dict);
    Py_VISIT(m->func_name);
    Py_VISIT(m->func_qualname);
    Py_VISIT(m->func_doc);
    Py_VISIT(m->func_globals);
    Py_VISIT(m->func_code);
    Py_VISIT(m->func_classobj);
    Py_VISIT(m->defaults_tuple);
    Py_VISIT(m->defaults_kwdict);
    if (m->defaults) {
        PyObject **pydefaults = __Pyx_CyFunction_Defaults(PyObject *, m);
        int i;
        for (i = 0; i < m->defaults_pyobjects; i++)
            Py_VISIT(pydefaults[i]);
    }
    return 0;
}
static PyObject *__Pyx_CyFunction_descr_get(PyObject *func, PyObject *obj, PyObject *type)
{
    __pyx_CyFunctionObject *m = (__pyx_CyFunctionObject *) func;
    if (m->flags & __Pyx_CYFUNCTION_STATICMETHOD) {
        Py_INCREF(func);
        return func;
    }
    if (m->flags & __Pyx_CYFUNCTION_CLASSMETHOD) {
        if (type == NULL)
            type = (PyObject *)(Py_TYPE(obj));
        return __Pyx_PyMethod_New(func, type, (PyObject *)(Py_TYPE(type)));
    }
    if (obj == Py_None)
        obj = NULL;
    return __Pyx_PyMethod_New(func, obj, type);
}
static PyObject*
__Pyx_CyFunction_repr(__pyx_CyFunctionObject *op)
{
#if PY_MAJOR_VERSION >= 3
    return PyUnicode_FromFormat("<cyfunction %U at %p>",
                                op->func_qualname, (void *)op);
#else
    return PyString_FromFormat("<cyfunction %s at %p>",
                               PyString_AsString(op->func_qualname), (void *)op);
#endif
}
static PyObject * __Pyx_CyFunction_CallMethod(PyObject *func, PyObject *self, PyObject *arg, PyObject *kw) {
    PyCFunctionObject* f = (PyCFunctionObject*)func;
    PyCFunction meth = f->m_ml->ml_meth;
    Py_ssize_t size;
    switch (f->m_ml->ml_flags & (METH_VARARGS | METH_KEYWORDS | METH_NOARGS | METH_O)) {
    case METH_VARARGS:
        if (likely(kw == NULL || PyDict_Size(kw) == 0))
            return (*meth)(self, arg);
        break;
    case METH_VARARGS | METH_KEYWORDS:
        return (*(PyCFunctionWithKeywords)meth)(self, arg, kw);
    case METH_NOARGS:
        if (likely(kw == NULL || PyDict_Size(kw) == 0)) {
            size = PyTuple_GET_SIZE(arg);
            if (likely(size == 0))
                return (*meth)(self, NULL);
            PyErr_Format(PyExc_TypeError,
                "%.200s() takes no arguments (%" CYTHON_FORMAT_SSIZE_T "d given)",
                f->m_ml->ml_name, size);
            return NULL;
        }
        break;
    case METH_O:
        if (likely(kw == NULL || PyDict_Size(kw) == 0)) {
            size = PyTuple_GET_SIZE(arg);
            if (likely(size == 1)) {
                PyObject *result, *arg0 = PySequence_ITEM(arg, 0);
                if (unlikely(!arg0)) return NULL;
                result = (*meth)(self, arg0);
                Py_DECREF(arg0);
                return result;
            }
            PyErr_Format(PyExc_TypeError,
                "%.200s() takes exactly one argument (%" CYTHON_FORMAT_SSIZE_T "d given)",
                f->m_ml->ml_name, size);
            return NULL;
        }
        break;
    default:
        PyErr_SetString(PyExc_SystemError, "Bad call flags in "
                        "__Pyx_CyFunction_Call. METH_OLDARGS is no "
                        "longer supported!");
        return NULL;
    }
    PyErr_Format(PyExc_TypeError, "%.200s() takes no keyword arguments",
                 f->m_ml->ml_name);
    return NULL;
}
static CYTHON_INLINE PyObject *__Pyx_CyFunction_Call(PyObject *func, PyObject *arg, PyObject *kw) {
    return __Pyx_CyFunction_CallMethod(func, ((PyCFunctionObject*)func)->m_self, arg, kw);
}
static PyObject *__Pyx_CyFunction_CallAsMethod(PyObject *func, PyObject *args, PyObject *kw) {
    PyObject *result;
    __pyx_CyFunctionObject *cyfunc = (__pyx_CyFunctionObject *) func;
    if ((cyfunc->flags & __Pyx_CYFUNCTION_CCLASS) && !(cyfunc->flags & __Pyx_CYFUNCTION_STATICMETHOD)) {
        Py_ssize_t argc;
        PyObject *new_args;
        PyObject *self;
        argc = PyTuple_GET_SIZE(args);
        new_args = PyTuple_GetSlice(args, 1, argc);
        if (unlikely(!new_args))
            return NULL;
        self = PyTuple_GetItem(args, 0);
        if (unlikely(!self)) {
            Py_DECREF(new_args);
            return NULL;
        }
        result = __Pyx_CyFunction_CallMethod(func, self, new_args, kw);
        Py_DECREF(new_args);
    } else {
        result = __Pyx_CyFunction_Call(func, args, kw);
    }
    return result;
}
static PyTypeObject __pyx_CyFunctionType_type = {
    PyVarObject_HEAD_INIT(0, 0)
    "cython_function_or_method",
    sizeof(__pyx_CyFunctionObject),
    0,
    (destructor) __Pyx_CyFunction_dealloc,
    0,
    0,
    0,
#if PY_MAJOR_VERSION < 3
    0,
#else
    0,
#endif
    (reprfunc) __Pyx_CyFunction_repr,
    0,
    0,
    0,
    0,
    __Pyx_CyFunction_CallAsMethod,
    0,
    0,
    0,
    0,
    Py_TPFLAGS_DEFAULT | Py_TPFLAGS_HAVE_GC,
    0,
    (traverseproc) __Pyx_CyFunction_traverse,
    (inquiry) __Pyx_CyFunction_clear,
    0,
#if PY_VERSION_HEX < 0x030500A0
    offsetof(__pyx_CyFunctionObject, func_weakreflist),
#else
    offsetof(PyCFunctionObject, m_weakreflist),
#endif
    0,
    0,
    __pyx_CyFunction_methods,
    __pyx_CyFunction_members,
    __pyx_CyFunction_getsets,
    0,
    0,
    __Pyx_CyFunction_descr_get,
    0,
    offsetof(__pyx_CyFunctionObject, func_dict),
    0,
    0,
    0,
    0,
    0,
    0,
    0,
    0,
    0,
    0,
    0,
    0,
#if PY_VERSION_HEX >= 0x030400a1
    0,
#endif
};
static int __pyx_CyFunction_init(void) {
    __pyx_CyFunctionType = __Pyx_FetchCommonType(&__pyx_CyFunctionType_type);
    if (__pyx_CyFunctionType == NULL) {
        return -1;
    }
    return 0;
}
static CYTHON_INLINE void *__Pyx_CyFunction_InitDefaults(PyObject *func, size_t size, int pyobjects) {
    __pyx_CyFunctionObject *m = (__pyx_CyFunctionObject *) func;
    m->defaults = PyObject_Malloc(size);
    if (!m->defaults)
        return PyErr_NoMemory();
    memset(m->defaults, 0, size);
    m->defaults_pyobjects = pyobjects;
    return m->defaults;
}
static CYTHON_INLINE void __Pyx_CyFunction_SetDefaultsTuple(PyObject *func, PyObject *tuple) {
    __pyx_CyFunctionObject *m = (__pyx_CyFunctionObject *) func;
    m->defaults_tuple = tuple;
    Py_INCREF(tuple);
}
static CYTHON_INLINE void __Pyx_CyFunction_SetDefaultsKwDict(PyObject *func, PyObject *dict) {
    __pyx_CyFunctionObject *m = (__pyx_CyFunctionObject *) func;
    m->defaults_kwdict = dict;
    Py_INCREF(dict);
}
static CYTHON_INLINE void __Pyx_CyFunction_SetAnnotationsDict(PyObject *func, PyObject *dict) {
    __pyx_CyFunctionObject *m = (__pyx_CyFunctionObject *) func;
    m->func_annotations = dict;
    Py_INCREF(dict);
}

/* decode_c_bytes */
          static CYTHON_INLINE PyObject* __Pyx_decode_c_bytes(
         const char* cstring, Py_ssize_t length, Py_ssize_t start, Py_ssize_t stop,
         const char* encoding, const char* errors,
         PyObject* (*decode_func)(const char *s, Py_ssize_t size, const char *errors)) {
    if (unlikely((start < 0) | (stop < 0))) {
        if (start < 0) {
            start += length;
            if (start < 0)
                start = 0;
        }
        if (stop < 0)
            stop += length;
    }
    if (stop > length)
        stop = length;
    length = stop - start;
    if (unlikely(length <= 0))
        return PyUnicode_FromUnicode(NULL, 0);
    cstring += start;
    if (decode_func) {
        return decode_func(cstring, length, errors);
    } else {
        return PyUnicode_Decode(cstring, length, encoding, errors);
    }
}

/* SetupReduce */
          static int __Pyx_setup_reduce_is_named(PyObject* meth, PyObject* name) {
  int ret;
  PyObject *name_attr;
  name_attr = __Pyx_PyObject_GetAttrStr(meth, __pyx_n_s_name_2);
  if (likely(name_attr)) {
      ret = PyObject_RichCompareBool(name_attr, name, Py_EQ);
  } else {
      ret = -1;
  }
  if (unlikely(ret < 0)) {
      PyErr_Clear();
      ret = 0;
  }
  Py_XDECREF(name_attr);
  return ret;
}
static int __Pyx_setup_reduce(PyObject* type_obj) {
    int ret = 0;
    PyObject *object_reduce = NULL;
    PyObject *object_reduce_ex = NULL;
    PyObject *reduce = NULL;
    PyObject *reduce_ex = NULL;
    PyObject *reduce_cython = NULL;
    PyObject *setstate = NULL;
    PyObject *setstate_cython = NULL;
#if CYTHON_USE_PYTYPE_LOOKUP
    if (_PyType_Lookup((PyTypeObject*)type_obj, __pyx_n_s_getstate)) goto GOOD;
#else
    if (PyObject_HasAttr(type_obj, __pyx_n_s_getstate)) goto GOOD;
#endif
#if CYTHON_USE_PYTYPE_LOOKUP
    object_reduce_ex = _PyType_Lookup(&PyBaseObject_Type, __pyx_n_s_reduce_ex); if (!object_reduce_ex) goto BAD;
#else
    object_reduce_ex = __Pyx_PyObject_GetAttrStr((PyObject*)&PyBaseObject_Type, __pyx_n_s_reduce_ex); if (!object_reduce_ex) goto BAD;
#endif
    reduce_ex = __Pyx_PyObject_GetAttrStr(type_obj, __pyx_n_s_reduce_ex); if (unlikely(!reduce_ex)) goto BAD;
    if (reduce_ex == object_reduce_ex) {
#if CYTHON_USE_PYTYPE_LOOKUP
        object_reduce = _PyType_Lookup(&PyBaseObject_Type, __pyx_n_s_reduce); if (!object_reduce) goto BAD;
#else
        object_reduce = __Pyx_PyObject_GetAttrStr((PyObject*)&PyBaseObject_Type, __pyx_n_s_reduce); if (!object_reduce) goto BAD;
#endif
        reduce = __Pyx_PyObject_GetAttrStr(type_obj, __pyx_n_s_reduce); if (unlikely(!reduce)) goto BAD;
        if (reduce == object_reduce || __Pyx_setup_reduce_is_named(reduce, __pyx_n_s_reduce_cython)) {
            reduce_cython = __Pyx_PyObject_GetAttrStr(type_obj, __pyx_n_s_reduce_cython); if (unlikely(!reduce_cython)) goto BAD;
            ret = PyDict_SetItem(((PyTypeObject*)type_obj)->tp_dict, __pyx_n_s_reduce, reduce_cython); if (unlikely(ret < 0)) goto BAD;
            ret = PyDict_DelItem(((PyTypeObject*)type_obj)->tp_dict, __pyx_n_s_reduce_cython); if (unlikely(ret < 0)) goto BAD;
            setstate = __Pyx_PyObject_GetAttrStr(type_obj, __pyx_n_s_setstate);
            if (!setstate) PyErr_Clear();
            if (!setstate || __Pyx_setup_reduce_is_named(setstate, __pyx_n_s_setstate_cython)) {
                setstate_cython = __Pyx_PyObject_GetAttrStr(type_obj, __pyx_n_s_setstate_cython); if (unlikely(!setstate_cython)) goto BAD;
                ret = PyDict_SetItem(((PyTypeObject*)type_obj)->tp_dict, __pyx_n_s_setstate, setstate_cython); if (unlikely(ret < 0)) goto BAD;
                ret = PyDict_DelItem(((PyTypeObject*)type_obj)->tp_dict, __pyx_n_s_setstate_cython); if (unlikely(ret < 0)) goto BAD;
            }
            PyType_Modified((PyTypeObject*)type_obj);
        }
    }
    goto GOOD;
BAD:
    if (!PyErr_Occurred())
        PyErr_Format(PyExc_RuntimeError, "Unable to initialize pickling for %s", ((PyTypeObject*)type_obj)->tp_name);
    ret = -1;
GOOD:
#if !CYTHON_COMPILING_IN_CPYTHON
    Py_XDECREF(object_reduce);
    Py_XDECREF(object_reduce_ex);
#endif
    Py_XDECREF(reduce);
    Py_XDECREF(reduce_ex);
    Py_XDECREF(reduce_cython);
    Py_XDECREF(setstate);
    Py_XDECREF(setstate_cython);
    return ret;
}

/* Import */
          static PyObject *__Pyx_Import(PyObject *name, PyObject *from_list, int level) {
    PyObject *empty_list = 0;
    PyObject *module = 0;
    PyObject *global_dict = 0;
    PyObject *empty_dict = 0;
    PyObject *list;
    #if PY_VERSION_HEX < 0x03030000
    PyObject *py_import;
    py_import = __Pyx_PyObject_GetAttrStr(__pyx_b, __pyx_n_s_import);
    if (!py_import)
        goto bad;
    #endif
    if (from_list)
        list = from_list;
    else {
        empty_list = PyList_New(0);
        if (!empty_list)
            goto bad;
        list = empty_list;
    }
    global_dict = PyModule_GetDict(__pyx_m);
    if (!global_dict)
        goto bad;
    empty_dict = PyDict_New();
    if (!empty_dict)
        goto bad;
    {
        #if PY_MAJOR_VERSION >= 3
        if (level == -1) {
            if (strchr(__Pyx_MODULE_NAME, '.')) {
                #if PY_VERSION_HEX < 0x03030000
                PyObject *py_level = PyInt_FromLong(1);
                if (!py_level)
                    goto bad;
                module = PyObject_CallFunctionObjArgs(py_import,
                    name, global_dict, empty_dict, list, py_level, NULL);
                Py_DECREF(py_level);
                #else
                module = PyImport_ImportModuleLevelObject(
                    name, global_dict, empty_dict, list, 1);
                #endif
                if (!module) {
                    if (!PyErr_ExceptionMatches(PyExc_ImportError))
                        goto bad;
                    PyErr_Clear();
                }
            }
            level = 0;
        }
        #endif
        if (!module) {
            #if PY_VERSION_HEX < 0x03030000
            PyObject *py_level = PyInt_FromLong(level);
            if (!py_level)
                goto bad;
            module = PyObject_CallFunctionObjArgs(py_import,
                name, global_dict, empty_dict, list, py_level, NULL);
            Py_DECREF(py_level);
            #else
            module = PyImport_ImportModuleLevelObject(
                name, global_dict, empty_dict, list, level);
            #endif
        }
    }
bad:
    #if PY_VERSION_HEX < 0x03030000
    Py_XDECREF(py_import);
    #endif
    Py_XDECREF(empty_list);
    Py_XDECREF(empty_dict);
    return module;
}

/* ImportFrom */
          static PyObject* __Pyx_ImportFrom(PyObject* module, PyObject* name) {
    PyObject* value = __Pyx_PyObject_GetAttrStr(module, name);
    if (unlikely(!value) && PyErr_ExceptionMatches(PyExc_AttributeError)) {
        PyErr_Format(PyExc_ImportError,
        #if PY_MAJOR_VERSION < 3
            "cannot import name %.230s", PyString_AS_STRING(name));
        #else
            "cannot import name %S", name);
        #endif
    }
    return value;
}

/* CLineInTraceback */
          static int __Pyx_CLineForTraceback(int c_line) {
#ifdef CYTHON_CLINE_IN_TRACEBACK
    return ((CYTHON_CLINE_IN_TRACEBACK)) ? c_line : 0;
#else
    PyObject *use_cline;
#if CYTHON_COMPILING_IN_CPYTHON
    PyObject **cython_runtime_dict = _PyObject_GetDictPtr(__pyx_cython_runtime);
    if (likely(cython_runtime_dict)) {
      use_cline = PyDict_GetItem(*cython_runtime_dict, __pyx_n_s_cline_in_traceback);
    } else
#endif
    {
      PyObject *ptype, *pvalue, *ptraceback;
      PyObject *use_cline_obj;
      PyErr_Fetch(&ptype, &pvalue, &ptraceback);
      use_cline_obj = __Pyx_PyObject_GetAttrStr(__pyx_cython_runtime, __pyx_n_s_cline_in_traceback);
      if (use_cline_obj) {
        use_cline = PyObject_Not(use_cline_obj) ? Py_False : Py_True;
        Py_DECREF(use_cline_obj);
      } else {
        use_cline = NULL;
      }
      PyErr_Restore(ptype, pvalue, ptraceback);
    }
    if (!use_cline) {
        c_line = 0;
        PyObject_SetAttr(__pyx_cython_runtime, __pyx_n_s_cline_in_traceback, Py_False);
    }
    else if (PyObject_Not(use_cline) != 0) {
        c_line = 0;
    }
    return c_line;
#endif
}

/* CodeObjectCache */
          static int __pyx_bisect_code_objects(__Pyx_CodeObjectCacheEntry* entries, int count, int code_line) {
    int start = 0, mid = 0, end = count - 1;
    if (end >= 0 && code_line > entries[end].code_line) {
        return count;
    }
    while (start < end) {
        mid = start + (end - start) / 2;
        if (code_line < entries[mid].code_line) {
            end = mid;
        } else if (code_line > entries[mid].code_line) {
             start = mid + 1;
        } else {
            return mid;
        }
    }
    if (code_line <= entries[mid].code_line) {
        return mid;
    } else {
        return mid + 1;
    }
}
static PyCodeObject *__pyx_find_code_object(int code_line) {
    PyCodeObject* code_object;
    int pos;
    if (unlikely(!code_line) || unlikely(!__pyx_code_cache.entries)) {
        return NULL;
    }
    pos = __pyx_bisect_code_objects(__pyx_code_cache.entries, __pyx_code_cache.count, code_line);
    if (unlikely(pos >= __pyx_code_cache.count) || unlikely(__pyx_code_cache.entries[pos].code_line != code_line)) {
        return NULL;
    }
    code_object = __pyx_code_cache.entries[pos].code_object;
    Py_INCREF(code_object);
    return code_object;
}
static void __pyx_insert_code_object(int code_line, PyCodeObject* code_object) {
    int pos, i;
    __Pyx_CodeObjectCacheEntry* entries = __pyx_code_cache.entries;
    if (unlikely(!code_line)) {
        return;
    }
    if (unlikely(!entries)) {
        entries = (__Pyx_CodeObjectCacheEntry*)PyMem_Malloc(64*sizeof(__Pyx_CodeObjectCacheEntry));
        if (likely(entries)) {
            __pyx_code_cache.entries = entries;
            __pyx_code_cache.max_count = 64;
            __pyx_code_cache.count = 1;
            entries[0].code_line = code_line;
            entries[0].code_object = code_object;
            Py_INCREF(code_object);
        }
        return;
    }
    pos = __pyx_bisect_code_objects(__pyx_code_cache.entries, __pyx_code_cache.count, code_line);
    if ((pos < __pyx_code_cache.count) && unlikely(__pyx_code_cache.entries[pos].code_line == code_line)) {
        PyCodeObject* tmp = entries[pos].code_object;
        entries[pos].code_object = code_object;
        Py_DECREF(tmp);
        return;
    }
    if (__pyx_code_cache.count == __pyx_code_cache.max_count) {
        int new_max = __pyx_code_cache.max_count + 64;
        entries = (__Pyx_CodeObjectCacheEntry*)PyMem_Realloc(
            __pyx_code_cache.entries, (size_t)new_max*sizeof(__Pyx_CodeObjectCacheEntry));
        if (unlikely(!entries)) {
            return;
        }
        __pyx_code_cache.entries = entries;
        __pyx_code_cache.max_count = new_max;
    }
    for (i=__pyx_code_cache.count; i>pos; i--) {
        entries[i] = entries[i-1];
    }
    entries[pos].code_line = code_line;
    entries[pos].code_object = code_object;
    __pyx_code_cache.count++;
    Py_INCREF(code_object);
}

/* AddTraceback */
          #include "compile.h"
#include "frameobject.h"
#include "traceback.h"
static PyCodeObject* __Pyx_CreateCodeObjectForTraceback(
            const char *funcname, int c_line,
            int py_line, const char *filename) {
    PyCodeObject *py_code = 0;
    PyObject *py_srcfile = 0;
    PyObject *py_funcname = 0;
    #if PY_MAJOR_VERSION < 3
    py_srcfile = PyString_FromString(filename);
    #else
    py_srcfile = PyUnicode_FromString(filename);
    #endif
    if (!py_srcfile) goto bad;
    if (c_line) {
        #if PY_MAJOR_VERSION < 3
        py_funcname = PyString_FromFormat( "%s (%s:%d)", funcname, __pyx_cfilenm, c_line);
        #else
        py_funcname = PyUnicode_FromFormat( "%s (%s:%d)", funcname, __pyx_cfilenm, c_line);
        #endif
    }
    else {
        #if PY_MAJOR_VERSION < 3
        py_funcname = PyString_FromString(funcname);
        #else
        py_funcname = PyUnicode_FromString(funcname);
        #endif
    }
    if (!py_funcname) goto bad;
    py_code = __Pyx_PyCode_New(
        0,
        0,
        0,
        0,
        0,
        __pyx_empty_bytes, /*PyObject *code,*/
        __pyx_empty_tuple, /*PyObject *consts,*/
        __pyx_empty_tuple, /*PyObject *names,*/
        __pyx_empty_tuple, /*PyObject *varnames,*/
        __pyx_empty_tuple, /*PyObject *freevars,*/
        __pyx_empty_tuple, /*PyObject *cellvars,*/
        py_srcfile,   /*PyObject *filename,*/
        py_funcname,  /*PyObject *name,*/
        py_line,
        __pyx_empty_bytes  /*PyObject *lnotab*/
    );
    Py_DECREF(py_srcfile);
    Py_DECREF(py_funcname);
    return py_code;
bad:
    Py_XDECREF(py_srcfile);
    Py_XDECREF(py_funcname);
    return NULL;
}
static void __Pyx_AddTraceback(const char *funcname, int c_line,
                               int py_line, const char *filename) {
    PyCodeObject *py_code = 0;
    PyFrameObject *py_frame = 0;
    if (c_line) {
        c_line = __Pyx_CLineForTraceback(c_line);
    }
    py_code = __pyx_find_code_object(c_line ? -c_line : py_line);
    if (!py_code) {
        py_code = __Pyx_CreateCodeObjectForTraceback(
            funcname, c_line, py_line, filename);
        if (!py_code) goto bad;
        __pyx_insert_code_object(c_line ? -c_line : py_line, py_code);
    }
    py_frame = PyFrame_New(
        PyThreadState_GET(), /*PyThreadState *tstate,*/
        py_code,             /*PyCodeObject *code,*/
        __pyx_d,      /*PyObject *globals,*/
        0                    /*PyObject *locals*/
    );
    if (!py_frame) goto bad;
    __Pyx_PyFrame_SetLineNumber(py_frame, py_line);
    PyTraceBack_Here(py_frame);
bad:
    Py_XDECREF(py_code);
    Py_XDECREF(py_frame);
}

/* CIntToPy */
          static CYTHON_INLINE PyObject* __Pyx_PyInt_From_int(int value) {
    const int neg_one = (int) -1, const_zero = (int) 0;
    const int is_unsigned = neg_one > const_zero;
    if (is_unsigned) {
        if (sizeof(int) < sizeof(long)) {
            return PyInt_FromLong((long) value);
        } else if (sizeof(int) <= sizeof(unsigned long)) {
            return PyLong_FromUnsignedLong((unsigned long) value);
#ifdef HAVE_LONG_LONG
        } else if (sizeof(int) <= sizeof(unsigned PY_LONG_LONG)) {
            return PyLong_FromUnsignedLongLong((unsigned PY_LONG_LONG) value);
#endif
        }
    } else {
        if (sizeof(int) <= sizeof(long)) {
            return PyInt_FromLong((long) value);
#ifdef HAVE_LONG_LONG
        } else if (sizeof(int) <= sizeof(PY_LONG_LONG)) {
            return PyLong_FromLongLong((PY_LONG_LONG) value);
#endif
        }
    }
    {
        int one = 1; int little = (int)*(unsigned char *)&one;
        unsigned char *bytes = (unsigned char *)&value;
        return _PyLong_FromByteArray(bytes, sizeof(int),
                                     little, !is_unsigned);
    }
}

/* CIntFromPyVerify */
          #define __PYX_VERIFY_RETURN_INT(target_type, func_type, func_value)\
    __PYX__VERIFY_RETURN_INT(target_type, func_type, func_value, 0)
#define __PYX_VERIFY_RETURN_INT_EXC(target_type, func_type, func_value)\
    __PYX__VERIFY_RETURN_INT(target_type, func_type, func_value, 1)
#define __PYX__VERIFY_RETURN_INT(target_type, func_type, func_value, exc)\
    {\
        func_type value = func_value;\
        if (sizeof(target_type) < sizeof(func_type)) {\
            if (unlikely(value != (func_type) (target_type) value)) {\
                func_type zero = 0;\
                if (exc && unlikely(value == (func_type)-1 && PyErr_Occurred()))\
                    return (target_type) -1;\
                if (is_unsigned && unlikely(value < zero))\
                    goto raise_neg_overflow;\
                else\
                    goto raise_overflow;\
            }\
        }\
        return (target_type) value;\
    }

static PyObject* __pyx_convert__to_py_struct__Region(struct Region s) {
            PyObject* res;
            PyObject* member;
            res = PyDict_New(); if (unlikely(!res)) return NULL;
            member = __Pyx_PyInt_From_int(s.start); if (unlikely(!member)) goto bad;
            if (unlikely(PyDict_SetItem(res, __pyx_n_s_start, member) < 0)) goto bad;
            Py_DECREF(member);
            member = __Pyx_PyInt_From_int(s.end); if (unlikely(!member)) goto bad;
            if (unlikely(PyDict_SetItem(res, __pyx_n_s_end, member) < 0)) goto bad;
            Py_DECREF(member);
            return res;
            bad:
            Py_XDECREF(member);
            Py_DECREF(res);
            return NULL;
          }
          /* CIntToPy */
          static CYTHON_INLINE PyObject* __Pyx_PyInt_From_char(char value) {
    const char neg_one = (char) -1, const_zero = (char) 0;
    const int is_unsigned = neg_one > const_zero;
    if (is_unsigned) {
        if (sizeof(char) < sizeof(long)) {
            return PyInt_FromLong((long) value);
        } else if (sizeof(char) <= sizeof(unsigned long)) {
            return PyLong_FromUnsignedLong((unsigned long) value);
#ifdef HAVE_LONG_LONG
        } else if (sizeof(char) <= sizeof(unsigned PY_LONG_LONG)) {
            return PyLong_FromUnsignedLongLong((unsigned PY_LONG_LONG) value);
#endif
        }
    } else {
        if (sizeof(char) <= sizeof(long)) {
            return PyInt_FromLong((long) value);
#ifdef HAVE_LONG_LONG
        } else if (sizeof(char) <= sizeof(PY_LONG_LONG)) {
            return PyLong_FromLongLong((PY_LONG_LONG) value);
#endif
        }
    }
    {
        int one = 1; int little = (int)*(unsigned char *)&one;
        unsigned char *bytes = (unsigned char *)&value;
        return _PyLong_FromByteArray(bytes, sizeof(char),
                                     little, !is_unsigned);
    }
}

static PyObject* __pyx_convert__to_py_struct__Codon(struct Codon s) {
            PyObject* res;
            PyObject* member;
            res = PyDict_New(); if (unlikely(!res)) return NULL;
            member = __Pyx_PyInt_From_int(s.cds_pos); if (unlikely(!member)) goto bad;
            if (unlikely(PyDict_SetItem(res, __pyx_n_s_cds_pos, member) < 0)) goto bad;
            Py_DECREF(member);
            member = __pyx_convert_PyObject_string_to_py_std__in_string(s.codon_seq); if (unlikely(!member)) goto bad;
            if (unlikely(PyDict_SetItem(res, __pyx_n_s_codon_seq, member) < 0)) goto bad;
            Py_DECREF(member);
            member = __Pyx_PyInt_From_int(s.intra_codon); if (unlikely(!member)) goto bad;
            if (unlikely(PyDict_SetItem(res, __pyx_n_s_intra_codon, member) < 0)) goto bad;
            Py_DECREF(member);
            member = __Pyx_PyInt_From_int(s.codon_number); if (unlikely(!member)) goto bad;
            if (unlikely(PyDict_SetItem(res, __pyx_n_s_codon_number, member) < 0)) goto bad;
            Py_DECREF(member);
            member = __pyx_convert_PyObject_string_to_py_std__in_string(s.initial_aa); if (unlikely(!member)) goto bad;
            if (unlikely(PyDict_SetItem(res, __pyx_n_s_initial_aa, member) < 0)) goto bad;
            Py_DECREF(member);
            member = __Pyx_PyInt_From_int(s.offset); if (unlikely(!member)) goto bad;
            if (unlikely(PyDict_SetItem(res, __pyx_n_s_offset, member) < 0)) goto bad;
            Py_DECREF(member);
            return res;
            bad:
            Py_XDECREF(member);
            Py_DECREF(res);
            return NULL;
          }
          /* CIntFromPy */
          static CYTHON_INLINE int __Pyx_PyInt_As_int(PyObject *x) {
    const int neg_one = (int) -1, const_zero = (int) 0;
    const int is_unsigned = neg_one > const_zero;
#if PY_MAJOR_VERSION < 3
    if (likely(PyInt_Check(x))) {
        if (sizeof(int) < sizeof(long)) {
            __PYX_VERIFY_RETURN_INT(int, long, PyInt_AS_LONG(x))
        } else {
            long val = PyInt_AS_LONG(x);
            if (is_unsigned && unlikely(val < 0)) {
                goto raise_neg_overflow;
            }
            return (int) val;
        }
    } else
#endif
    if (likely(PyLong_Check(x))) {
        if (is_unsigned) {
#if CYTHON_USE_PYLONG_INTERNALS
            const digit* digits = ((PyLongObject*)x)->ob_digit;
            switch (Py_SIZE(x)) {
                case  0: return (int) 0;
                case  1: __PYX_VERIFY_RETURN_INT(int, digit, digits[0])
                case 2:
                    if (8 * sizeof(int) > 1 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 2 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(int, unsigned long, (((((unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(int) >= 2 * PyLong_SHIFT) {
                            return (int) (((((int)digits[1]) << PyLong_SHIFT) | (int)digits[0]));
                        }
                    }
                    break;
                case 3:
                    if (8 * sizeof(int) > 2 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 3 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(int, unsigned long, (((((((unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(int) >= 3 * PyLong_SHIFT) {
                            return (int) (((((((int)digits[2]) << PyLong_SHIFT) | (int)digits[1]) << PyLong_SHIFT) | (int)digits[0]));
                        }
                    }
                    break;
                case 4:
                    if (8 * sizeof(int) > 3 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 4 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(int, unsigned long, (((((((((unsigned long)digits[3]) << PyLong_SHIFT) | (unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(int) >= 4 * PyLong_SHIFT) {
                            return (int) (((((((((int)digits[3]) << PyLong_SHIFT) | (int)digits[2]) << PyLong_SHIFT) | (int)digits[1]) << PyLong_SHIFT) | (int)digits[0]));
                        }
                    }
                    break;
            }
#endif
#if CYTHON_COMPILING_IN_CPYTHON
            if (unlikely(Py_SIZE(x) < 0)) {
                goto raise_neg_overflow;
            }
#else
            {
                int result = PyObject_RichCompareBool(x, Py_False, Py_LT);
                if (unlikely(result < 0))
                    return (int) -1;
                if (unlikely(result == 1))
                    goto raise_neg_overflow;
            }
#endif
            if (sizeof(int) <= sizeof(unsigned long)) {
                __PYX_VERIFY_RETURN_INT_EXC(int, unsigned long, PyLong_AsUnsignedLong(x))
#ifdef HAVE_LONG_LONG
            } else if (sizeof(int) <= sizeof(unsigned PY_LONG_LONG)) {
                __PYX_VERIFY_RETURN_INT_EXC(int, unsigned PY_LONG_LONG, PyLong_AsUnsignedLongLong(x))
#endif
            }
        } else {
#if CYTHON_USE_PYLONG_INTERNALS
            const digit* digits = ((PyLongObject*)x)->ob_digit;
            switch (Py_SIZE(x)) {
                case  0: return (int) 0;
                case -1: __PYX_VERIFY_RETURN_INT(int, sdigit, (sdigit) (-(sdigit)digits[0]))
                case  1: __PYX_VERIFY_RETURN_INT(int,  digit, +digits[0])
                case -2:
                    if (8 * sizeof(int) - 1 > 1 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 2 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(int, long, -(long) (((((unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(int) - 1 > 2 * PyLong_SHIFT) {
                            return (int) (((int)-1)*(((((int)digits[1]) << PyLong_SHIFT) | (int)digits[0])));
                        }
                    }
                    break;
                case 2:
                    if (8 * sizeof(int) > 1 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 2 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(int, unsigned long, (((((unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(int) - 1 > 2 * PyLong_SHIFT) {
                            return (int) ((((((int)digits[1]) << PyLong_SHIFT) | (int)digits[0])));
                        }
                    }
                    break;
                case -3:
                    if (8 * sizeof(int) - 1 > 2 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 3 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(int, long, -(long) (((((((unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(int) - 1 > 3 * PyLong_SHIFT) {
                            return (int) (((int)-1)*(((((((int)digits[2]) << PyLong_SHIFT) | (int)digits[1]) << PyLong_SHIFT) | (int)digits[0])));
                        }
                    }
                    break;
                case 3:
                    if (8 * sizeof(int) > 2 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 3 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(int, unsigned long, (((((((unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(int) - 1 > 3 * PyLong_SHIFT) {
                            return (int) ((((((((int)digits[2]) << PyLong_SHIFT) | (int)digits[1]) << PyLong_SHIFT) | (int)digits[0])));
                        }
                    }
                    break;
                case -4:
                    if (8 * sizeof(int) - 1 > 3 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 4 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(int, long, -(long) (((((((((unsigned long)digits[3]) << PyLong_SHIFT) | (unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(int) - 1 > 4 * PyLong_SHIFT) {
                            return (int) (((int)-1)*(((((((((int)digits[3]) << PyLong_SHIFT) | (int)digits[2]) << PyLong_SHIFT) | (int)digits[1]) << PyLong_SHIFT) | (int)digits[0])));
                        }
                    }
                    break;
                case 4:
                    if (8 * sizeof(int) > 3 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 4 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(int, unsigned long, (((((((((unsigned long)digits[3]) << PyLong_SHIFT) | (unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(int) - 1 > 4 * PyLong_SHIFT) {
                            return (int) ((((((((((int)digits[3]) << PyLong_SHIFT) | (int)digits[2]) << PyLong_SHIFT) | (int)digits[1]) << PyLong_SHIFT) | (int)digits[0])));
                        }
                    }
                    break;
            }
#endif
            if (sizeof(int) <= sizeof(long)) {
                __PYX_VERIFY_RETURN_INT_EXC(int, long, PyLong_AsLong(x))
#ifdef HAVE_LONG_LONG
            } else if (sizeof(int) <= sizeof(PY_LONG_LONG)) {
                __PYX_VERIFY_RETURN_INT_EXC(int, PY_LONG_LONG, PyLong_AsLongLong(x))
#endif
            }
        }
        {
#if CYTHON_COMPILING_IN_PYPY && !defined(_PyLong_AsByteArray)
            PyErr_SetString(PyExc_RuntimeError,
                            "_PyLong_AsByteArray() not available in PyPy, cannot convert large numbers");
#else
            int val;
            PyObject *v = __Pyx_PyNumber_IntOrLong(x);
 #if PY_MAJOR_VERSION < 3
            if (likely(v) && !PyLong_Check(v)) {
                PyObject *tmp = v;
                v = PyNumber_Long(tmp);
                Py_DECREF(tmp);
            }
 #endif
            if (likely(v)) {
                int one = 1; int is_little = (int)*(unsigned char *)&one;
                unsigned char *bytes = (unsigned char *)&val;
                int ret = _PyLong_AsByteArray((PyLongObject *)v,
                                              bytes, sizeof(val),
                                              is_little, !is_unsigned);
                Py_DECREF(v);
                if (likely(!ret))
                    return val;
            }
#endif
            return (int) -1;
        }
    } else {
        int val;
        PyObject *tmp = __Pyx_PyNumber_IntOrLong(x);
        if (!tmp) return (int) -1;
        val = __Pyx_PyInt_As_int(tmp);
        Py_DECREF(tmp);
        return val;
    }
raise_overflow:
    PyErr_SetString(PyExc_OverflowError,
        "value too large to convert to int");
    return (int) -1;
raise_neg_overflow:
    PyErr_SetString(PyExc_OverflowError,
        "can't convert negative value to int");
    return (int) -1;
}

/* CIntFromPy */
          static CYTHON_INLINE size_t __Pyx_PyInt_As_size_t(PyObject *x) {
    const size_t neg_one = (size_t) -1, const_zero = (size_t) 0;
    const int is_unsigned = neg_one > const_zero;
#if PY_MAJOR_VERSION < 3
    if (likely(PyInt_Check(x))) {
        if (sizeof(size_t) < sizeof(long)) {
            __PYX_VERIFY_RETURN_INT(size_t, long, PyInt_AS_LONG(x))
        } else {
            long val = PyInt_AS_LONG(x);
            if (is_unsigned && unlikely(val < 0)) {
                goto raise_neg_overflow;
            }
            return (size_t) val;
        }
    } else
#endif
    if (likely(PyLong_Check(x))) {
        if (is_unsigned) {
#if CYTHON_USE_PYLONG_INTERNALS
            const digit* digits = ((PyLongObject*)x)->ob_digit;
            switch (Py_SIZE(x)) {
                case  0: return (size_t) 0;
                case  1: __PYX_VERIFY_RETURN_INT(size_t, digit, digits[0])
                case 2:
                    if (8 * sizeof(size_t) > 1 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 2 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(size_t, unsigned long, (((((unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(size_t) >= 2 * PyLong_SHIFT) {
                            return (size_t) (((((size_t)digits[1]) << PyLong_SHIFT) | (size_t)digits[0]));
                        }
                    }
                    break;
                case 3:
                    if (8 * sizeof(size_t) > 2 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 3 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(size_t, unsigned long, (((((((unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(size_t) >= 3 * PyLong_SHIFT) {
                            return (size_t) (((((((size_t)digits[2]) << PyLong_SHIFT) | (size_t)digits[1]) << PyLong_SHIFT) | (size_t)digits[0]));
                        }
                    }
                    break;
                case 4:
                    if (8 * sizeof(size_t) > 3 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 4 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(size_t, unsigned long, (((((((((unsigned long)digits[3]) << PyLong_SHIFT) | (unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(size_t) >= 4 * PyLong_SHIFT) {
                            return (size_t) (((((((((size_t)digits[3]) << PyLong_SHIFT) | (size_t)digits[2]) << PyLong_SHIFT) | (size_t)digits[1]) << PyLong_SHIFT) | (size_t)digits[0]));
                        }
                    }
                    break;
            }
#endif
#if CYTHON_COMPILING_IN_CPYTHON
            if (unlikely(Py_SIZE(x) < 0)) {
                goto raise_neg_overflow;
            }
#else
            {
                int result = PyObject_RichCompareBool(x, Py_False, Py_LT);
                if (unlikely(result < 0))
                    return (size_t) -1;
                if (unlikely(result == 1))
                    goto raise_neg_overflow;
            }
#endif
            if (sizeof(size_t) <= sizeof(unsigned long)) {
                __PYX_VERIFY_RETURN_INT_EXC(size_t, unsigned long, PyLong_AsUnsignedLong(x))
#ifdef HAVE_LONG_LONG
            } else if (sizeof(size_t) <= sizeof(unsigned PY_LONG_LONG)) {
                __PYX_VERIFY_RETURN_INT_EXC(size_t, unsigned PY_LONG_LONG, PyLong_AsUnsignedLongLong(x))
#endif
            }
        } else {
#if CYTHON_USE_PYLONG_INTERNALS
            const digit* digits = ((PyLongObject*)x)->ob_digit;
            switch (Py_SIZE(x)) {
                case  0: return (size_t) 0;
                case -1: __PYX_VERIFY_RETURN_INT(size_t, sdigit, (sdigit) (-(sdigit)digits[0]))
                case  1: __PYX_VERIFY_RETURN_INT(size_t,  digit, +digits[0])
                case -2:
                    if (8 * sizeof(size_t) - 1 > 1 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 2 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(size_t, long, -(long) (((((unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(size_t) - 1 > 2 * PyLong_SHIFT) {
                            return (size_t) (((size_t)-1)*(((((size_t)digits[1]) << PyLong_SHIFT) | (size_t)digits[0])));
                        }
                    }
                    break;
                case 2:
                    if (8 * sizeof(size_t) > 1 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 2 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(size_t, unsigned long, (((((unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(size_t) - 1 > 2 * PyLong_SHIFT) {
                            return (size_t) ((((((size_t)digits[1]) << PyLong_SHIFT) | (size_t)digits[0])));
                        }
                    }
                    break;
                case -3:
                    if (8 * sizeof(size_t) - 1 > 2 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 3 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(size_t, long, -(long) (((((((unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(size_t) - 1 > 3 * PyLong_SHIFT) {
                            return (size_t) (((size_t)-1)*(((((((size_t)digits[2]) << PyLong_SHIFT) | (size_t)digits[1]) << PyLong_SHIFT) | (size_t)digits[0])));
                        }
                    }
                    break;
                case 3:
                    if (8 * sizeof(size_t) > 2 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 3 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(size_t, unsigned long, (((((((unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(size_t) - 1 > 3 * PyLong_SHIFT) {
                            return (size_t) ((((((((size_t)digits[2]) << PyLong_SHIFT) | (size_t)digits[1]) << PyLong_SHIFT) | (size_t)digits[0])));
                        }
                    }
                    break;
                case -4:
                    if (8 * sizeof(size_t) - 1 > 3 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 4 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(size_t, long, -(long) (((((((((unsigned long)digits[3]) << PyLong_SHIFT) | (unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(size_t) - 1 > 4 * PyLong_SHIFT) {
                            return (size_t) (((size_t)-1)*(((((((((size_t)digits[3]) << PyLong_SHIFT) | (size_t)digits[2]) << PyLong_SHIFT) | (size_t)digits[1]) << PyLong_SHIFT) | (size_t)digits[0])));
                        }
                    }
                    break;
                case 4:
                    if (8 * sizeof(size_t) > 3 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 4 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(size_t, unsigned long, (((((((((unsigned long)digits[3]) << PyLong_SHIFT) | (unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(size_t) - 1 > 4 * PyLong_SHIFT) {
                            return (size_t) ((((((((((size_t)digits[3]) << PyLong_SHIFT) | (size_t)digits[2]) << PyLong_SHIFT) | (size_t)digits[1]) << PyLong_SHIFT) | (size_t)digits[0])));
                        }
                    }
                    break;
            }
#endif
            if (sizeof(size_t) <= sizeof(long)) {
                __PYX_VERIFY_RETURN_INT_EXC(size_t, long, PyLong_AsLong(x))
#ifdef HAVE_LONG_LONG
            } else if (sizeof(size_t) <= sizeof(PY_LONG_LONG)) {
                __PYX_VERIFY_RETURN_INT_EXC(size_t, PY_LONG_LONG, PyLong_AsLongLong(x))
#endif
            }
        }
        {
#if CYTHON_COMPILING_IN_PYPY && !defined(_PyLong_AsByteArray)
            PyErr_SetString(PyExc_RuntimeError,
                            "_PyLong_AsByteArray() not available in PyPy, cannot convert large numbers");
#else
            size_t val;
            PyObject *v = __Pyx_PyNumber_IntOrLong(x);
 #if PY_MAJOR_VERSION < 3
            if (likely(v) && !PyLong_Check(v)) {
                PyObject *tmp = v;
                v = PyNumber_Long(tmp);
                Py_DECREF(tmp);
            }
 #endif
            if (likely(v)) {
                int one = 1; int is_little = (int)*(unsigned char *)&one;
                unsigned char *bytes = (unsigned char *)&val;
                int ret = _PyLong_AsByteArray((PyLongObject *)v,
                                              bytes, sizeof(val),
                                              is_little, !is_unsigned);
                Py_DECREF(v);
                if (likely(!ret))
                    return val;
            }
#endif
            return (size_t) -1;
        }
    } else {
        size_t val;
        PyObject *tmp = __Pyx_PyNumber_IntOrLong(x);
        if (!tmp) return (size_t) -1;
        val = __Pyx_PyInt_As_size_t(tmp);
        Py_DECREF(tmp);
        return val;
    }
raise_overflow:
    PyErr_SetString(PyExc_OverflowError,
        "value too large to convert to size_t");
    return (size_t) -1;
raise_neg_overflow:
    PyErr_SetString(PyExc_OverflowError,
        "can't convert negative value to size_t");
    return (size_t) -1;
}

/* CIntToPy */
          static CYTHON_INLINE PyObject* __Pyx_PyInt_From_long(long value) {
    const long neg_one = (long) -1, const_zero = (long) 0;
    const int is_unsigned = neg_one > const_zero;
    if (is_unsigned) {
        if (sizeof(long) < sizeof(long)) {
            return PyInt_FromLong((long) value);
        } else if (sizeof(long) <= sizeof(unsigned long)) {
            return PyLong_FromUnsignedLong((unsigned long) value);
#ifdef HAVE_LONG_LONG
        } else if (sizeof(long) <= sizeof(unsigned PY_LONG_LONG)) {
            return PyLong_FromUnsignedLongLong((unsigned PY_LONG_LONG) value);
#endif
        }
    } else {
        if (sizeof(long) <= sizeof(long)) {
            return PyInt_FromLong((long) value);
#ifdef HAVE_LONG_LONG
        } else if (sizeof(long) <= sizeof(PY_LONG_LONG)) {
            return PyLong_FromLongLong((PY_LONG_LONG) value);
#endif
        }
    }
    {
        int one = 1; int little = (int)*(unsigned char *)&one;
        unsigned char *bytes = (unsigned char *)&value;
        return _PyLong_FromByteArray(bytes, sizeof(long),
                                     little, !is_unsigned);
    }
}

/* CIntFromPy */
          static CYTHON_INLINE long __Pyx_PyInt_As_long(PyObject *x) {
    const long neg_one = (long) -1, const_zero = (long) 0;
    const int is_unsigned = neg_one > const_zero;
#if PY_MAJOR_VERSION < 3
    if (likely(PyInt_Check(x))) {
        if (sizeof(long) < sizeof(long)) {
            __PYX_VERIFY_RETURN_INT(long, long, PyInt_AS_LONG(x))
        } else {
            long val = PyInt_AS_LONG(x);
            if (is_unsigned && unlikely(val < 0)) {
                goto raise_neg_overflow;
            }
            return (long) val;
        }
    } else
#endif
    if (likely(PyLong_Check(x))) {
        if (is_unsigned) {
#if CYTHON_USE_PYLONG_INTERNALS
            const digit* digits = ((PyLongObject*)x)->ob_digit;
            switch (Py_SIZE(x)) {
                case  0: return (long) 0;
                case  1: __PYX_VERIFY_RETURN_INT(long, digit, digits[0])
                case 2:
                    if (8 * sizeof(long) > 1 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 2 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(long, unsigned long, (((((unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(long) >= 2 * PyLong_SHIFT) {
                            return (long) (((((long)digits[1]) << PyLong_SHIFT) | (long)digits[0]));
                        }
                    }
                    break;
                case 3:
                    if (8 * sizeof(long) > 2 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 3 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(long, unsigned long, (((((((unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(long) >= 3 * PyLong_SHIFT) {
                            return (long) (((((((long)digits[2]) << PyLong_SHIFT) | (long)digits[1]) << PyLong_SHIFT) | (long)digits[0]));
                        }
                    }
                    break;
                case 4:
                    if (8 * sizeof(long) > 3 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 4 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(long, unsigned long, (((((((((unsigned long)digits[3]) << PyLong_SHIFT) | (unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(long) >= 4 * PyLong_SHIFT) {
                            return (long) (((((((((long)digits[3]) << PyLong_SHIFT) | (long)digits[2]) << PyLong_SHIFT) | (long)digits[1]) << PyLong_SHIFT) | (long)digits[0]));
                        }
                    }
                    break;
            }
#endif
#if CYTHON_COMPILING_IN_CPYTHON
            if (unlikely(Py_SIZE(x) < 0)) {
                goto raise_neg_overflow;
            }
#else
            {
                int result = PyObject_RichCompareBool(x, Py_False, Py_LT);
                if (unlikely(result < 0))
                    return (long) -1;
                if (unlikely(result == 1))
                    goto raise_neg_overflow;
            }
#endif
            if (sizeof(long) <= sizeof(unsigned long)) {
                __PYX_VERIFY_RETURN_INT_EXC(long, unsigned long, PyLong_AsUnsignedLong(x))
#ifdef HAVE_LONG_LONG
            } else if (sizeof(long) <= sizeof(unsigned PY_LONG_LONG)) {
                __PYX_VERIFY_RETURN_INT_EXC(long, unsigned PY_LONG_LONG, PyLong_AsUnsignedLongLong(x))
#endif
            }
        } else {
#if CYTHON_USE_PYLONG_INTERNALS
            const digit* digits = ((PyLongObject*)x)->ob_digit;
            switch (Py_SIZE(x)) {
                case  0: return (long) 0;
                case -1: __PYX_VERIFY_RETURN_INT(long, sdigit, (sdigit) (-(sdigit)digits[0]))
                case  1: __PYX_VERIFY_RETURN_INT(long,  digit, +digits[0])
                case -2:
                    if (8 * sizeof(long) - 1 > 1 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 2 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(long, long, -(long) (((((unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(long) - 1 > 2 * PyLong_SHIFT) {
                            return (long) (((long)-1)*(((((long)digits[1]) << PyLong_SHIFT) | (long)digits[0])));
                        }
                    }
                    break;
                case 2:
                    if (8 * sizeof(long) > 1 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 2 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(long, unsigned long, (((((unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(long) - 1 > 2 * PyLong_SHIFT) {
                            return (long) ((((((long)digits[1]) << PyLong_SHIFT) | (long)digits[0])));
                        }
                    }
                    break;
                case -3:
                    if (8 * sizeof(long) - 1 > 2 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 3 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(long, long, -(long) (((((((unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(long) - 1 > 3 * PyLong_SHIFT) {
                            return (long) (((long)-1)*(((((((long)digits[2]) << PyLong_SHIFT) | (long)digits[1]) << PyLong_SHIFT) | (long)digits[0])));
                        }
                    }
                    break;
                case 3:
                    if (8 * sizeof(long) > 2 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 3 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(long, unsigned long, (((((((unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(long) - 1 > 3 * PyLong_SHIFT) {
                            return (long) ((((((((long)digits[2]) << PyLong_SHIFT) | (long)digits[1]) << PyLong_SHIFT) | (long)digits[0])));
                        }
                    }
                    break;
                case -4:
                    if (8 * sizeof(long) - 1 > 3 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 4 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(long, long, -(long) (((((((((unsigned long)digits[3]) << PyLong_SHIFT) | (unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(long) - 1 > 4 * PyLong_SHIFT) {
                            return (long) (((long)-1)*(((((((((long)digits[3]) << PyLong_SHIFT) | (long)digits[2]) << PyLong_SHIFT) | (long)digits[1]) << PyLong_SHIFT) | (long)digits[0])));
                        }
                    }
                    break;
                case 4:
                    if (8 * sizeof(long) > 3 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 4 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(long, unsigned long, (((((((((unsigned long)digits[3]) << PyLong_SHIFT) | (unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(long) - 1 > 4 * PyLong_SHIFT) {
                            return (long) ((((((((((long)digits[3]) << PyLong_SHIFT) | (long)digits[2]) << PyLong_SHIFT) | (long)digits[1]) << PyLong_SHIFT) | (long)digits[0])));
                        }
                    }
                    break;
            }
#endif
            if (sizeof(long) <= sizeof(long)) {
                __PYX_VERIFY_RETURN_INT_EXC(long, long, PyLong_AsLong(x))
#ifdef HAVE_LONG_LONG
            } else if (sizeof(long) <= sizeof(PY_LONG_LONG)) {
                __PYX_VERIFY_RETURN_INT_EXC(long, PY_LONG_LONG, PyLong_AsLongLong(x))
#endif
            }
        }
        {
#if CYTHON_COMPILING_IN_PYPY && !defined(_PyLong_AsByteArray)
            PyErr_SetString(PyExc_RuntimeError,
                            "_PyLong_AsByteArray() not available in PyPy, cannot convert large numbers");
#else
            long val;
            PyObject *v = __Pyx_PyNumber_IntOrLong(x);
 #if PY_MAJOR_VERSION < 3
            if (likely(v) && !PyLong_Check(v)) {
                PyObject *tmp = v;
                v = PyNumber_Long(tmp);
                Py_DECREF(tmp);
            }
 #endif
            if (likely(v)) {
                int one = 1; int is_little = (int)*(unsigned char *)&one;
                unsigned char *bytes = (unsigned char *)&val;
                int ret = _PyLong_AsByteArray((PyLongObject *)v,
                                              bytes, sizeof(val),
                                              is_little, !is_unsigned);
                Py_DECREF(v);
                if (likely(!ret))
                    return val;
            }
#endif
            return (long) -1;
        }
    } else {
        long val;
        PyObject *tmp = __Pyx_PyNumber_IntOrLong(x);
        if (!tmp) return (long) -1;
        val = __Pyx_PyInt_As_long(tmp);
        Py_DECREF(tmp);
        return val;
    }
raise_overflow:
    PyErr_SetString(PyExc_OverflowError,
        "value too large to convert to long");
    return (long) -1;
raise_neg_overflow:
    PyErr_SetString(PyExc_OverflowError,
        "can't convert negative value to long");
    return (long) -1;
}

/* SwapException */
          #if CYTHON_FAST_THREAD_STATE
static CYTHON_INLINE void __Pyx__ExceptionSwap(PyThreadState *tstate, PyObject **type, PyObject **value, PyObject **tb) {
    PyObject *tmp_type, *tmp_value, *tmp_tb;
    tmp_type = tstate->exc_type;
    tmp_value = tstate->exc_value;
    tmp_tb = tstate->exc_traceback;
    tstate->exc_type = *type;
    tstate->exc_value = *value;
    tstate->exc_traceback = *tb;
    *type = tmp_type;
    *value = tmp_value;
    *tb = tmp_tb;
}
#else
static CYTHON_INLINE void __Pyx_ExceptionSwap(PyObject **type, PyObject **value, PyObject **tb) {
    PyObject *tmp_type, *tmp_value, *tmp_tb;
    PyErr_GetExcInfo(&tmp_type, &tmp_value, &tmp_tb);
    PyErr_SetExcInfo(*type, *value, *tb);
    *type = tmp_type;
    *value = tmp_value;
    *tb = tmp_tb;
}
#endif

/* PyObjectCallMethod1 */
          static PyObject* __Pyx_PyObject_CallMethod1(PyObject* obj, PyObject* method_name, PyObject* arg) {
    PyObject *method, *result = NULL;
    method = __Pyx_PyObject_GetAttrStr(obj, method_name);
    if (unlikely(!method)) goto done;
#if CYTHON_UNPACK_METHODS
    if (likely(PyMethod_Check(method))) {
        PyObject *self = PyMethod_GET_SELF(method);
        if (likely(self)) {
            PyObject *args;
            PyObject *function = PyMethod_GET_FUNCTION(method);
            #if CYTHON_FAST_PYCALL
            if (PyFunction_Check(function)) {
                PyObject *args[2] = {self, arg};
                result = __Pyx_PyFunction_FastCall(function, args, 2);
                goto done;
            }
            #endif
            #if CYTHON_FAST_PYCCALL
            if (__Pyx_PyFastCFunction_Check(function)) {
                PyObject *args[2] = {self, arg};
                result = __Pyx_PyCFunction_FastCall(function, args, 2);
                goto done;
            }
            #endif
            args = PyTuple_New(2);
            if (unlikely(!args)) goto done;
            Py_INCREF(self);
            PyTuple_SET_ITEM(args, 0, self);
            Py_INCREF(arg);
            PyTuple_SET_ITEM(args, 1, arg);
            Py_INCREF(function);
            Py_DECREF(method); method = NULL;
            result = __Pyx_PyObject_Call(function, args, NULL);
            Py_DECREF(args);
            Py_DECREF(function);
            return result;
        }
    }
#endif
    result = __Pyx_PyObject_CallOneArg(method, arg);
done:
    Py_XDECREF(method);
    return result;
}

/* CoroutineBase */
          #include <structmember.h>
#include <frameobject.h>
static PyObject *__Pyx_Coroutine_Send(PyObject *self, PyObject *value);
static PyObject *__Pyx_Coroutine_Close(PyObject *self);
static PyObject *__Pyx_Coroutine_Throw(PyObject *gen, PyObject *args);
#define __Pyx_Coroutine_Undelegate(gen) Py_CLEAR((gen)->yieldfrom)
#if 1 || PY_VERSION_HEX < 0x030300B0
static int __Pyx_PyGen_FetchStopIterationValue(PyObject **pvalue) {
    PyObject *et, *ev, *tb;
    PyObject *value = NULL;
    __Pyx_PyThreadState_declare
    __Pyx_PyThreadState_assign
    __Pyx_ErrFetch(&et, &ev, &tb);
    if (!et) {
        Py_XDECREF(tb);
        Py_XDECREF(ev);
        Py_INCREF(Py_None);
        *pvalue = Py_None;
        return 0;
    }
    if (likely(et == PyExc_StopIteration)) {
        if (!ev) {
            Py_INCREF(Py_None);
            value = Py_None;
        }
#if PY_VERSION_HEX >= 0x030300A0
        else if (Py_TYPE(ev) == (PyTypeObject*)PyExc_StopIteration) {
            value = ((PyStopIterationObject *)ev)->value;
            Py_INCREF(value);
            Py_DECREF(ev);
        }
#endif
        else if (unlikely(PyTuple_Check(ev))) {
            if (PyTuple_GET_SIZE(ev) >= 1) {
#if CYTHON_ASSUME_SAFE_MACROS && !CYTHON_AVOID_BORROWED_REFS
                value = PyTuple_GET_ITEM(ev, 0);
                Py_INCREF(value);
#else
                value = PySequence_ITEM(ev, 0);
#endif
            } else {
                Py_INCREF(Py_None);
                value = Py_None;
            }
            Py_DECREF(ev);
        }
        else if (!PyObject_TypeCheck(ev, (PyTypeObject*)PyExc_StopIteration)) {
            value = ev;
        }
        if (likely(value)) {
            Py_XDECREF(tb);
            Py_DECREF(et);
            *pvalue = value;
            return 0;
        }
    } else if (!PyErr_GivenExceptionMatches(et, PyExc_StopIteration)) {
        __Pyx_ErrRestore(et, ev, tb);
        return -1;
    }
    PyErr_NormalizeException(&et, &ev, &tb);
    if (unlikely(!PyObject_TypeCheck(ev, (PyTypeObject*)PyExc_StopIteration))) {
        __Pyx_ErrRestore(et, ev, tb);
        return -1;
    }
    Py_XDECREF(tb);
    Py_DECREF(et);
#if PY_VERSION_HEX >= 0x030300A0
    value = ((PyStopIterationObject *)ev)->value;
    Py_INCREF(value);
    Py_DECREF(ev);
#else
    {
        PyObject* args = __Pyx_PyObject_GetAttrStr(ev, __pyx_n_s_args);
        Py_DECREF(ev);
        if (likely(args)) {
            value = PySequence_GetItem(args, 0);
            Py_DECREF(args);
        }
        if (unlikely(!value)) {
            __Pyx_ErrRestore(NULL, NULL, NULL);
            Py_INCREF(Py_None);
            value = Py_None;
        }
    }
#endif
    *pvalue = value;
    return 0;
}
#endif
static CYTHON_INLINE
void __Pyx_Coroutine_ExceptionClear(__pyx_CoroutineObject *self) {
    PyObject *exc_type = self->exc_type;
    PyObject *exc_value = self->exc_value;
    PyObject *exc_traceback = self->exc_traceback;
    self->exc_type = NULL;
    self->exc_value = NULL;
    self->exc_traceback = NULL;
    Py_XDECREF(exc_type);
    Py_XDECREF(exc_value);
    Py_XDECREF(exc_traceback);
}
static CYTHON_INLINE
int __Pyx_Coroutine_CheckRunning(__pyx_CoroutineObject *gen) {
    if (unlikely(gen->is_running)) {
        PyErr_SetString(PyExc_ValueError,
                        "generator already executing");
        return 1;
    }
    return 0;
}
static CYTHON_INLINE
PyObject *__Pyx_Coroutine_SendEx(__pyx_CoroutineObject *self, PyObject *value) {
    PyObject *retval;
    __Pyx_PyThreadState_declare
    assert(!self->is_running);
    if (unlikely(self->resume_label == 0)) {
        if (unlikely(value && value != Py_None)) {
            PyErr_SetString(PyExc_TypeError,
                            "can't send non-None value to a "
                            "just-started generator");
            return NULL;
        }
    }
    if (unlikely(self->resume_label == -1)) {
        PyErr_SetNone(PyExc_StopIteration);
        return NULL;
    }
    __Pyx_PyThreadState_assign
    if (value) {
#if CYTHON_COMPILING_IN_PYPY || CYTHON_COMPILING_IN_PYSTON
#else
        if (self->exc_traceback) {
            PyTracebackObject *tb = (PyTracebackObject *) self->exc_traceback;
            PyFrameObject *f = tb->tb_frame;
            Py_XINCREF(__pyx_tstate->frame);
            assert(f->f_back == NULL);
            f->f_back = __pyx_tstate->frame;
        }
#endif
        __Pyx_ExceptionSwap(&self->exc_type, &self->exc_value,
                            &self->exc_traceback);
    } else {
        __Pyx_Coroutine_ExceptionClear(self);
    }
    self->is_running = 1;
    retval = self->body((PyObject *) self, value);
    self->is_running = 0;
    if (retval) {
        __Pyx_ExceptionSwap(&self->exc_type, &self->exc_value,
                            &self->exc_traceback);
#if CYTHON_COMPILING_IN_PYPY || CYTHON_COMPILING_IN_PYSTON
#else
        if (self->exc_traceback) {
            PyTracebackObject *tb = (PyTracebackObject *) self->exc_traceback;
            PyFrameObject *f = tb->tb_frame;
            Py_CLEAR(f->f_back);
        }
#endif
    } else {
        __Pyx_Coroutine_ExceptionClear(self);
    }
    return retval;
}
static CYTHON_INLINE
PyObject *__Pyx_Coroutine_MethodReturn(PyObject *retval) {
    if (unlikely(!retval && !PyErr_Occurred())) {
        PyErr_SetNone(PyExc_StopIteration);
    }
    return retval;
}
static CYTHON_INLINE
PyObject *__Pyx_Coroutine_FinishDelegation(__pyx_CoroutineObject *gen) {
    PyObject *ret;
    PyObject *val = NULL;
    __Pyx_Coroutine_Undelegate(gen);
    __Pyx_PyGen_FetchStopIterationValue(&val);
    ret = __Pyx_Coroutine_SendEx(gen, val);
    Py_XDECREF(val);
    return ret;
}
static PyObject *__Pyx_Coroutine_Send(PyObject *self, PyObject *value) {
    PyObject *retval;
    __pyx_CoroutineObject *gen = (__pyx_CoroutineObject*) self;
    PyObject *yf = gen->yieldfrom;
    if (unlikely(__Pyx_Coroutine_CheckRunning(gen)))
        return NULL;
    if (yf) {
        PyObject *ret;
        gen->is_running = 1;
        #ifdef __Pyx_Generator_USED
        if (__Pyx_Generator_CheckExact(yf)) {
            ret = __Pyx_Coroutine_Send(yf, value);
        } else
        #endif
        #ifdef __Pyx_Coroutine_USED
        if (__Pyx_Coroutine_CheckExact(yf)) {
            ret = __Pyx_Coroutine_Send(yf, value);
        } else
        #endif
        {
            if (value == Py_None)
                ret = Py_TYPE(yf)->tp_iternext(yf);
            else
                ret = __Pyx_PyObject_CallMethod1(yf, __pyx_n_s_send, value);
        }
        gen->is_running = 0;
        if (likely(ret)) {
            return ret;
        }
        retval = __Pyx_Coroutine_FinishDelegation(gen);
    } else {
        retval = __Pyx_Coroutine_SendEx(gen, value);
    }
    return __Pyx_Coroutine_MethodReturn(retval);
}
static int __Pyx_Coroutine_CloseIter(__pyx_CoroutineObject *gen, PyObject *yf) {
    PyObject *retval = NULL;
    int err = 0;
    #ifdef __Pyx_Generator_USED
    if (__Pyx_Generator_CheckExact(yf)) {
        retval = __Pyx_Coroutine_Close(yf);
        if (!retval)
            return -1;
    } else
    #endif
    #ifdef __Pyx_Coroutine_USED
    if (__Pyx_Coroutine_CheckExact(yf)) {
        retval = __Pyx_Coroutine_Close(yf);
        if (!retval)
            return -1;
    } else
    #endif
    {
        PyObject *meth;
        gen->is_running = 1;
        meth = __Pyx_PyObject_GetAttrStr(yf, __pyx_n_s_close);
        if (unlikely(!meth)) {
            if (!PyErr_ExceptionMatches(PyExc_AttributeError)) {
                PyErr_WriteUnraisable(yf);
            }
            PyErr_Clear();
        } else {
            retval = PyObject_CallFunction(meth, NULL);
            Py_DECREF(meth);
            if (!retval)
                err = -1;
        }
        gen->is_running = 0;
    }
    Py_XDECREF(retval);
    return err;
}
static PyObject *__Pyx_Generator_Next(PyObject *self) {
    __pyx_CoroutineObject *gen = (__pyx_CoroutineObject*) self;
    PyObject *yf = gen->yieldfrom;
    if (unlikely(__Pyx_Coroutine_CheckRunning(gen)))
        return NULL;
    if (yf) {
        PyObject *ret;
        gen->is_running = 1;
        #ifdef __Pyx_Generator_USED
        if (__Pyx_Generator_CheckExact(yf)) {
            ret = __Pyx_Generator_Next(yf);
        } else
        #endif
            ret = Py_TYPE(yf)->tp_iternext(yf);
        gen->is_running = 0;
        if (likely(ret)) {
            return ret;
        }
        return __Pyx_Coroutine_FinishDelegation(gen);
    }
    return __Pyx_Coroutine_SendEx(gen, Py_None);
}
static PyObject *__Pyx_Coroutine_Close(PyObject *self) {
    __pyx_CoroutineObject *gen = (__pyx_CoroutineObject *) self;
    PyObject *retval, *raised_exception;
    PyObject *yf = gen->yieldfrom;
    int err = 0;
    if (unlikely(__Pyx_Coroutine_CheckRunning(gen)))
        return NULL;
    if (yf) {
        Py_INCREF(yf);
        err = __Pyx_Coroutine_CloseIter(gen, yf);
        __Pyx_Coroutine_Undelegate(gen);
        Py_DECREF(yf);
    }
    if (err == 0)
        PyErr_SetNone(PyExc_GeneratorExit);
    retval = __Pyx_Coroutine_SendEx(gen, NULL);
    if (retval) {
        Py_DECREF(retval);
        PyErr_SetString(PyExc_RuntimeError,
                        "generator ignored GeneratorExit");
        return NULL;
    }
    raised_exception = PyErr_Occurred();
    if (!raised_exception
        || raised_exception == PyExc_StopIteration
        || raised_exception == PyExc_GeneratorExit
        || PyErr_GivenExceptionMatches(raised_exception, PyExc_GeneratorExit)
        || PyErr_GivenExceptionMatches(raised_exception, PyExc_StopIteration))
    {
        if (raised_exception) PyErr_Clear();
        Py_INCREF(Py_None);
        return Py_None;
    }
    return NULL;
}
static PyObject *__Pyx_Coroutine_Throw(PyObject *self, PyObject *args) {
    __pyx_CoroutineObject *gen = (__pyx_CoroutineObject *) self;
    PyObject *typ;
    PyObject *tb = NULL;
    PyObject *val = NULL;
    PyObject *yf = gen->yieldfrom;
    if (!PyArg_UnpackTuple(args, (char *)"throw", 1, 3, &typ, &val, &tb))
        return NULL;
    if (unlikely(__Pyx_Coroutine_CheckRunning(gen)))
        return NULL;
    if (yf) {
        PyObject *ret;
        Py_INCREF(yf);
        if (PyErr_GivenExceptionMatches(typ, PyExc_GeneratorExit)) {
            int err = __Pyx_Coroutine_CloseIter(gen, yf);
            Py_DECREF(yf);
            __Pyx_Coroutine_Undelegate(gen);
            if (err < 0)
                return __Pyx_Coroutine_MethodReturn(__Pyx_Coroutine_SendEx(gen, NULL));
            goto throw_here;
        }
        gen->is_running = 1;
        #ifdef __Pyx_Generator_USED
        if (__Pyx_Generator_CheckExact(yf)) {
            ret = __Pyx_Coroutine_Throw(yf, args);
        } else
        #endif
        #ifdef __Pyx_Coroutine_USED
        if (__Pyx_Coroutine_CheckExact(yf)) {
            ret = __Pyx_Coroutine_Throw(yf, args);
        } else
        #endif
        {
            PyObject *meth = __Pyx_PyObject_GetAttrStr(yf, __pyx_n_s_throw);
            if (unlikely(!meth)) {
                Py_DECREF(yf);
                if (!PyErr_ExceptionMatches(PyExc_AttributeError)) {
                    gen->is_running = 0;
                    return NULL;
                }
                PyErr_Clear();
                __Pyx_Coroutine_Undelegate(gen);
                gen->is_running = 0;
                goto throw_here;
            }
            ret = PyObject_CallObject(meth, args);
            Py_DECREF(meth);
        }
        gen->is_running = 0;
        Py_DECREF(yf);
        if (!ret) {
            ret = __Pyx_Coroutine_FinishDelegation(gen);
        }
        return __Pyx_Coroutine_MethodReturn(ret);
    }
throw_here:
    __Pyx_Raise(typ, val, tb, NULL);
    return __Pyx_Coroutine_MethodReturn(__Pyx_Coroutine_SendEx(gen, NULL));
}
static int __Pyx_Coroutine_traverse(PyObject *self, visitproc visit, void *arg) {
    __pyx_CoroutineObject *gen = (__pyx_CoroutineObject *) self;
    Py_VISIT(gen->closure);
    Py_VISIT(gen->classobj);
    Py_VISIT(gen->yieldfrom);
    Py_VISIT(gen->exc_type);
    Py_VISIT(gen->exc_value);
    Py_VISIT(gen->exc_traceback);
    return 0;
}
static int __Pyx_Coroutine_clear(PyObject *self) {
    __pyx_CoroutineObject *gen = (__pyx_CoroutineObject *) self;
    Py_CLEAR(gen->closure);
    Py_CLEAR(gen->classobj);
    Py_CLEAR(gen->yieldfrom);
    Py_CLEAR(gen->exc_type);
    Py_CLEAR(gen->exc_value);
    Py_CLEAR(gen->exc_traceback);
    Py_CLEAR(gen->gi_name);
    Py_CLEAR(gen->gi_qualname);
    return 0;
}
static void __Pyx_Coroutine_dealloc(PyObject *self) {
    __pyx_CoroutineObject *gen = (__pyx_CoroutineObject *) self;
    PyObject_GC_UnTrack(gen);
    if (gen->gi_weakreflist != NULL)
        PyObject_ClearWeakRefs(self);
    if (gen->resume_label > 0) {
        PyObject_GC_Track(self);
#if PY_VERSION_HEX >= 0x030400a1
        if (PyObject_CallFinalizerFromDealloc(self))
#else
        Py_TYPE(gen)->tp_del(self);
        if (self->ob_refcnt > 0)
#endif
        {
            return;
        }
        PyObject_GC_UnTrack(self);
    }
    __Pyx_Coroutine_clear(self);
    PyObject_GC_Del(gen);
}
static void __Pyx_Coroutine_del(PyObject *self) {
    PyObject *res;
    PyObject *error_type, *error_value, *error_traceback;
    __pyx_CoroutineObject *gen = (__pyx_CoroutineObject *) self;
    __Pyx_PyThreadState_declare
    if (gen->resume_label <= 0)
        return ;
#if PY_VERSION_HEX < 0x030400a1
    assert(self->ob_refcnt == 0);
    self->ob_refcnt = 1;
#endif
    __Pyx_PyThreadState_assign
    __Pyx_ErrFetch(&error_type, &error_value, &error_traceback);
    res = __Pyx_Coroutine_Close(self);
    if (res == NULL)
        PyErr_WriteUnraisable(self);
    else
        Py_DECREF(res);
    __Pyx_ErrRestore(error_type, error_value, error_traceback);
#if PY_VERSION_HEX < 0x030400a1
    assert(self->ob_refcnt > 0);
    if (--self->ob_refcnt == 0) {
        return;
    }
    {
        Py_ssize_t refcnt = self->ob_refcnt;
        _Py_NewReference(self);
        self->ob_refcnt = refcnt;
    }
#if CYTHON_COMPILING_IN_CPYTHON
    assert(PyType_IS_GC(self->ob_type) &&
           _Py_AS_GC(self)->gc.gc_refs != _PyGC_REFS_UNTRACKED);
    _Py_DEC_REFTOTAL;
#endif
#ifdef COUNT_ALLOCS
    --Py_TYPE(self)->tp_frees;
    --Py_TYPE(self)->tp_allocs;
#endif
#endif
}
static PyObject *
__Pyx_Coroutine_get_name(__pyx_CoroutineObject *self)
{
    PyObject *name = self->gi_name;
    if (unlikely(!name)) name = Py_None;
    Py_INCREF(name);
    return name;
}
static int
__Pyx_Coroutine_set_name(__pyx_CoroutineObject *self, PyObject *value)
{
    PyObject *tmp;
#if PY_MAJOR_VERSION >= 3
    if (unlikely(value == NULL || !PyUnicode_Check(value))) {
#else
    if (unlikely(value == NULL || !PyString_Check(value))) {
#endif
        PyErr_SetString(PyExc_TypeError,
                        "__name__ must be set to a string object");
        return -1;
    }
    tmp = self->gi_name;
    Py_INCREF(value);
    self->gi_name = value;
    Py_XDECREF(tmp);
    return 0;
}
static PyObject *
__Pyx_Coroutine_get_qualname(__pyx_CoroutineObject *self)
{
    PyObject *name = self->gi_qualname;
    if (unlikely(!name)) name = Py_None;
    Py_INCREF(name);
    return name;
}
static int
__Pyx_Coroutine_set_qualname(__pyx_CoroutineObject *self, PyObject *value)
{
    PyObject *tmp;
#if PY_MAJOR_VERSION >= 3
    if (unlikely(value == NULL || !PyUnicode_Check(value))) {
#else
    if (unlikely(value == NULL || !PyString_Check(value))) {
#endif
        PyErr_SetString(PyExc_TypeError,
                        "__qualname__ must be set to a string object");
        return -1;
    }
    tmp = self->gi_qualname;
    Py_INCREF(value);
    self->gi_qualname = value;
    Py_XDECREF(tmp);
    return 0;
}
static __pyx_CoroutineObject *__Pyx__Coroutine_New(
            PyTypeObject* type, __pyx_coroutine_body_t body, PyObject *closure,
            PyObject *name, PyObject *qualname, PyObject *module_name) {
    __pyx_CoroutineObject *gen = PyObject_GC_New(__pyx_CoroutineObject, type);
    if (gen == NULL)
        return NULL;
    gen->body = body;
    gen->closure = closure;
    Py_XINCREF(closure);
    gen->is_running = 0;
    gen->resume_label = 0;
    gen->classobj = NULL;
    gen->yieldfrom = NULL;
    gen->exc_type = NULL;
    gen->exc_value = NULL;
    gen->exc_traceback = NULL;
    gen->gi_weakreflist = NULL;
    Py_XINCREF(qualname);
    gen->gi_qualname = qualname;
    Py_XINCREF(name);
    gen->gi_name = name;
    Py_XINCREF(module_name);
    gen->gi_modulename = module_name;
    PyObject_GC_Track(gen);
    return gen;
}

/* PatchModuleWithCoroutine */
              static PyObject* __Pyx_Coroutine_patch_module(PyObject* module, const char* py_code) {
#if defined(__Pyx_Generator_USED) || defined(__Pyx_Coroutine_USED)
    int result;
    PyObject *globals, *result_obj;
    globals = PyDict_New();  if (unlikely(!globals)) goto ignore;
    result = PyDict_SetItemString(globals, "_cython_coroutine_type",
    #ifdef __Pyx_Coroutine_USED
        (PyObject*)__pyx_CoroutineType);
    #else
        Py_None);
    #endif
    if (unlikely(result < 0)) goto ignore;
    result = PyDict_SetItemString(globals, "_cython_generator_type",
    #ifdef __Pyx_Generator_USED
        (PyObject*)__pyx_GeneratorType);
    #else
        Py_None);
    #endif
    if (unlikely(result < 0)) goto ignore;
    if (unlikely(PyDict_SetItemString(globals, "_module", module) < 0)) goto ignore;
    if (unlikely(PyDict_SetItemString(globals, "__builtins__", __pyx_b) < 0)) goto ignore;
    result_obj = PyRun_String(py_code, Py_file_input, globals, globals);
    if (unlikely(!result_obj)) goto ignore;
    Py_DECREF(result_obj);
    Py_DECREF(globals);
    return module;
ignore:
    Py_XDECREF(globals);
    PyErr_WriteUnraisable(module);
    if (unlikely(PyErr_WarnEx(PyExc_RuntimeWarning, "Cython module failed to patch module with custom type", 1) < 0)) {
        Py_DECREF(module);
        module = NULL;
    }
#else
    py_code++;
#endif
    return module;
}

/* PatchGeneratorABC */
              #ifndef CYTHON_REGISTER_ABCS
#define CYTHON_REGISTER_ABCS 1
#endif
#if defined(__Pyx_Generator_USED) || defined(__Pyx_Coroutine_USED)
static PyObject* __Pyx_patch_abc_module(PyObject *module);
static PyObject* __Pyx_patch_abc_module(PyObject *module) {
    module = __Pyx_Coroutine_patch_module(
        module, ""
"if _cython_generator_type is not None:\n"
"    try: Generator = _module.Generator\n"
"    except AttributeError: pass\n"
"    else: Generator.register(_cython_generator_type)\n"
"if _cython_coroutine_type is not None:\n"
"    try: Coroutine = _module.Coroutine\n"
"    except AttributeError: pass\n"
"    else: Coroutine.register(_cython_coroutine_type)\n"
    );
    return module;
}
#endif
static int __Pyx_patch_abc(void) {
#if defined(__Pyx_Generator_USED) || defined(__Pyx_Coroutine_USED)
    static int abc_patched = 0;
    if (CYTHON_REGISTER_ABCS && !abc_patched) {
        PyObject *module;
        module = PyImport_ImportModule((PY_VERSION_HEX >= 0x03030000) ? "collections.abc" : "collections");
        if (!module) {
            PyErr_WriteUnraisable(NULL);
            if (unlikely(PyErr_WarnEx(PyExc_RuntimeWarning,
                    ((PY_VERSION_HEX >= 0x03030000) ?
                        "Cython module failed to register with collections.abc module" :
                        "Cython module failed to register with collections module"), 1) < 0)) {
                return -1;
            }
        } else {
            module = __Pyx_patch_abc_module(module);
            abc_patched = 1;
            if (unlikely(!module))
                return -1;
            Py_DECREF(module);
        }
        module = PyImport_ImportModule("backports_abc");
        if (module) {
            module = __Pyx_patch_abc_module(module);
            Py_XDECREF(module);
        }
        if (!module) {
            PyErr_Clear();
        }
    }
#else
    if ((0)) __Pyx_Coroutine_patch_module(NULL, NULL);
#endif
    return 0;
}

/* Generator */
              static PyMethodDef __pyx_Generator_methods[] = {
    {"send", (PyCFunction) __Pyx_Coroutine_Send, METH_O,
     (char*) PyDoc_STR("send(arg) -> send 'arg' into generator,\nreturn next yielded value or raise StopIteration.")},
    {"throw", (PyCFunction) __Pyx_Coroutine_Throw, METH_VARARGS,
     (char*) PyDoc_STR("throw(typ[,val[,tb]]) -> raise exception in generator,\nreturn next yielded value or raise StopIteration.")},
    {"close", (PyCFunction) __Pyx_Coroutine_Close, METH_NOARGS,
     (char*) PyDoc_STR("close() -> raise GeneratorExit inside generator.")},
    {0, 0, 0, 0}
};
static PyMemberDef __pyx_Generator_memberlist[] = {
    {(char *) "gi_running", T_BOOL, offsetof(__pyx_CoroutineObject, is_running), READONLY, NULL},
    {(char*) "gi_yieldfrom", T_OBJECT, offsetof(__pyx_CoroutineObject, yieldfrom), READONLY,
     (char*) PyDoc_STR("object being iterated by 'yield from', or None")},
    {0, 0, 0, 0, 0}
};
static PyGetSetDef __pyx_Generator_getsets[] = {
    {(char *) "__name__", (getter)__Pyx_Coroutine_get_name, (setter)__Pyx_Coroutine_set_name,
     (char*) PyDoc_STR("name of the generator"), 0},
    {(char *) "__qualname__", (getter)__Pyx_Coroutine_get_qualname, (setter)__Pyx_Coroutine_set_qualname,
     (char*) PyDoc_STR("qualified name of the generator"), 0},
    {0, 0, 0, 0, 0}
};
static PyTypeObject __pyx_GeneratorType_type = {
    PyVarObject_HEAD_INIT(0, 0)
    "generator",
    sizeof(__pyx_CoroutineObject),
    0,
    (destructor) __Pyx_Coroutine_dealloc,
    0,
    0,
    0,
    0,
    0,
    0,
    0,
    0,
    0,
    0,
    0,
    0,
    0,
    0,
    Py_TPFLAGS_DEFAULT | Py_TPFLAGS_HAVE_GC | Py_TPFLAGS_HAVE_FINALIZE,
    0,
    (traverseproc) __Pyx_Coroutine_traverse,
    0,
    0,
    offsetof(__pyx_CoroutineObject, gi_weakreflist),
    0,
    (iternextfunc) __Pyx_Generator_Next,
    __pyx_Generator_methods,
    __pyx_Generator_memberlist,
    __pyx_Generator_getsets,
    0,
    0,
    0,
    0,
    0,
    0,
    0,
    0,
    0,
    0,
    0,
    0,
    0,
    0,
    0,
#if PY_VERSION_HEX >= 0x030400a1
    0,
#else
    __Pyx_Coroutine_del,
#endif
    0,
#if PY_VERSION_HEX >= 0x030400a1
    __Pyx_Coroutine_del,
#endif
};
static int __pyx_Generator_init(void) {
    __pyx_GeneratorType_type.tp_getattro = PyObject_GenericGetAttr;
    __pyx_GeneratorType_type.tp_iter = PyObject_SelfIter;
    __pyx_GeneratorType = __Pyx_FetchCommonType(&__pyx_GeneratorType_type);
    if (unlikely(!__pyx_GeneratorType)) {
        return -1;
    }
    return 0;
}

/* CheckBinaryVersion */
              static int __Pyx_check_binary_version(void) {
    char ctversion[4], rtversion[4];
    PyOS_snprintf(ctversion, 4, "%d.%d", PY_MAJOR_VERSION, PY_MINOR_VERSION);
    PyOS_snprintf(rtversion, 4, "%s", Py_GetVersion());
    if (ctversion[0] != rtversion[0] || ctversion[2] != rtversion[2]) {
        char message[200];
        PyOS_snprintf(message, sizeof(message),
                      "compiletime version %s of module '%.100s' "
                      "does not match runtime version %s",
                      ctversion, __Pyx_MODULE_NAME, rtversion);
        return PyErr_WarnEx(NULL, message, 1);
    }
    return 0;
}

/* InitStrings */
              static int __Pyx_InitStrings(__Pyx_StringTabEntry *t) {
    while (t->p) {
        #if PY_MAJOR_VERSION < 3
        if (t->is_unicode) {
            *t->p = PyUnicode_DecodeUTF8(t->s, t->n - 1, NULL);
        } else if (t->intern) {
            *t->p = PyString_InternFromString(t->s);
        } else {
            *t->p = PyString_FromStringAndSize(t->s, t->n - 1);
        }
        #else
        if (t->is_unicode | t->is_str) {
            if (t->intern) {
                *t->p = PyUnicode_InternFromString(t->s);
            } else if (t->encoding) {
                *t->p = PyUnicode_Decode(t->s, t->n - 1, t->encoding, NULL);
            } else {
                *t->p = PyUnicode_FromStringAndSize(t->s, t->n - 1);
            }
        } else {
            *t->p = PyBytes_FromStringAndSize(t->s, t->n - 1);
        }
        #endif
        if (!*t->p)
            return -1;
        if (PyObject_Hash(*t->p) == -1)
            PyErr_Clear();
        ++t;
    }
    return 0;
}

static CYTHON_INLINE PyObject* __Pyx_PyUnicode_FromString(const char* c_str) {
    return __Pyx_PyUnicode_FromStringAndSize(c_str, (Py_ssize_t)strlen(c_str));
}
static CYTHON_INLINE const char* __Pyx_PyObject_AsString(PyObject* o) {
    Py_ssize_t ignore;
    return __Pyx_PyObject_AsStringAndSize(o, &ignore);
}
static CYTHON_INLINE const char* __Pyx_PyObject_AsStringAndSize(PyObject* o, Py_ssize_t *length) {
#if CYTHON_COMPILING_IN_CPYTHON && (__PYX_DEFAULT_STRING_ENCODING_IS_ASCII || __PYX_DEFAULT_STRING_ENCODING_IS_DEFAULT)
    if (
#if PY_MAJOR_VERSION < 3 && __PYX_DEFAULT_STRING_ENCODING_IS_ASCII
            __Pyx_sys_getdefaultencoding_not_ascii &&
#endif
            PyUnicode_Check(o)) {
#if PY_VERSION_HEX < 0x03030000
        char* defenc_c;
        PyObject* defenc = _PyUnicode_AsDefaultEncodedString(o, NULL);
        if (!defenc) return NULL;
        defenc_c = PyBytes_AS_STRING(defenc);
#if __PYX_DEFAULT_STRING_ENCODING_IS_ASCII
        {
            char* end = defenc_c + PyBytes_GET_SIZE(defenc);
            char* c;
            for (c = defenc_c; c < end; c++) {
                if ((unsigned char) (*c) >= 128) {
                    PyUnicode_AsASCIIString(o);
                    return NULL;
                }
            }
        }
#endif
        *length = PyBytes_GET_SIZE(defenc);
        return defenc_c;
#else
        if (__Pyx_PyUnicode_READY(o) == -1) return NULL;
#if __PYX_DEFAULT_STRING_ENCODING_IS_ASCII
        if (PyUnicode_IS_ASCII(o)) {
            *length = PyUnicode_GET_LENGTH(o);
            return PyUnicode_AsUTF8(o);
        } else {
            PyUnicode_AsASCIIString(o);
            return NULL;
        }
#else
        return PyUnicode_AsUTF8AndSize(o, length);
#endif
#endif
    } else
#endif
#if (!CYTHON_COMPILING_IN_PYPY) || (defined(PyByteArray_AS_STRING) && defined(PyByteArray_GET_SIZE))
    if (PyByteArray_Check(o)) {
        *length = PyByteArray_GET_SIZE(o);
        return PyByteArray_AS_STRING(o);
    } else
#endif
    {
        char* result;
        int r = PyBytes_AsStringAndSize(o, &result, length);
        if (unlikely(r < 0)) {
            return NULL;
        } else {
            return result;
        }
    }
}
static CYTHON_INLINE int __Pyx_PyObject_IsTrue(PyObject* x) {
   int is_true = x == Py_True;
   if (is_true | (x == Py_False) | (x == Py_None)) return is_true;
   else return PyObject_IsTrue(x);
}
static CYTHON_INLINE PyObject* __Pyx_PyNumber_IntOrLong(PyObject* x) {
#if CYTHON_USE_TYPE_SLOTS
  PyNumberMethods *m;
#endif
  const char *name = NULL;
  PyObject *res = NULL;
#if PY_MAJOR_VERSION < 3
  if (PyInt_Check(x) || PyLong_Check(x))
#else
  if (PyLong_Check(x))
#endif
    return __Pyx_NewRef(x);
#if CYTHON_USE_TYPE_SLOTS
  m = Py_TYPE(x)->tp_as_number;
  #if PY_MAJOR_VERSION < 3
  if (m && m->nb_int) {
    name = "int";
    res = PyNumber_Int(x);
  }
  else if (m && m->nb_long) {
    name = "long";
    res = PyNumber_Long(x);
  }
  #else
  if (m && m->nb_int) {
    name = "int";
    res = PyNumber_Long(x);
  }
  #endif
#else
  res = PyNumber_Int(x);
#endif
  if (res) {
#if PY_MAJOR_VERSION < 3
    if (!PyInt_Check(res) && !PyLong_Check(res)) {
#else
    if (!PyLong_Check(res)) {
#endif
      PyErr_Format(PyExc_TypeError,
                   "__%.4s__ returned non-%.4s (type %.200s)",
                   name, name, Py_TYPE(res)->tp_name);
      Py_DECREF(res);
      return NULL;
    }
  }
  else if (!PyErr_Occurred()) {
    PyErr_SetString(PyExc_TypeError,
                    "an integer is required");
  }
  return res;
}
static CYTHON_INLINE Py_ssize_t __Pyx_PyIndex_AsSsize_t(PyObject* b) {
  Py_ssize_t ival;
  PyObject *x;
#if PY_MAJOR_VERSION < 3
  if (likely(PyInt_CheckExact(b))) {
    if (sizeof(Py_ssize_t) >= sizeof(long))
        return PyInt_AS_LONG(b);
    else
        return PyInt_AsSsize_t(x);
  }
#endif
  if (likely(PyLong_CheckExact(b))) {
    #if CYTHON_USE_PYLONG_INTERNALS
    const digit* digits = ((PyLongObject*)b)->ob_digit;
    const Py_ssize_t size = Py_SIZE(b);
    if (likely(__Pyx_sst_abs(size) <= 1)) {
        ival = likely(size) ? digits[0] : 0;
        if (size == -1) ival = -ival;
        return ival;
    } else {
      switch (size) {
         case 2:
           if (8 * sizeof(Py_ssize_t) > 2 * PyLong_SHIFT) {
             return (Py_ssize_t) (((((size_t)digits[1]) << PyLong_SHIFT) | (size_t)digits[0]));
           }
           break;
         case -2:
           if (8 * sizeof(Py_ssize_t) > 2 * PyLong_SHIFT) {
             return -(Py_ssize_t) (((((size_t)digits[1]) << PyLong_SHIFT) | (size_t)digits[0]));
           }
           break;
         case 3:
           if (8 * sizeof(Py_ssize_t) > 3 * PyLong_SHIFT) {
             return (Py_ssize_t) (((((((size_t)digits[2]) << PyLong_SHIFT) | (size_t)digits[1]) << PyLong_SHIFT) | (size_t)digits[0]));
           }
           break;
         case -3:
           if (8 * sizeof(Py_ssize_t) > 3 * PyLong_SHIFT) {
             return -(Py_ssize_t) (((((((size_t)digits[2]) << PyLong_SHIFT) | (size_t)digits[1]) << PyLong_SHIFT) | (size_t)digits[0]));
           }
           break;
         case 4:
           if (8 * sizeof(Py_ssize_t) > 4 * PyLong_SHIFT) {
             return (Py_ssize_t) (((((((((size_t)digits[3]) << PyLong_SHIFT) | (size_t)digits[2]) << PyLong_SHIFT) | (size_t)digits[1]) << PyLong_SHIFT) | (size_t)digits[0]));
           }
           break;
         case -4:
           if (8 * sizeof(Py_ssize_t) > 4 * PyLong_SHIFT) {
             return -(Py_ssize_t) (((((((((size_t)digits[3]) << PyLong_SHIFT) | (size_t)digits[2]) << PyLong_SHIFT) | (size_t)digits[1]) << PyLong_SHIFT) | (size_t)digits[0]));
           }
           break;
      }
    }
    #endif
    return PyLong_AsSsize_t(b);
  }
  x = PyNumber_Index(b);
  if (!x) return -1;
  ival = PyInt_AsSsize_t(x);
  Py_DECREF(x);
  return ival;
}
static CYTHON_INLINE PyObject * __Pyx_PyInt_FromSize_t(size_t ival) {
    return PyInt_FromSize_t(ival);
}


#endif /* Py_PYTHON_H */
