/* Generated by Cython 0.29.13 */

/* BEGIN: Cython Metadata
{
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            "-fno-strict-aliasing"
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        "name": "CRADLE.CorrectBias.calculateOnebp",
        "sources": [
            "CRADLE/CorrectBias/calculateOnebp.pyx"
        ]
    },
    "module_name": "CRADLE.CorrectBias.calculateOnebp"
}
END: Cython Metadata */

#define PY_SSIZE_T_CLEAN
#include "Python.h"
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#define CYTHON_FORMAT_SSIZE_T "z"
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#define __PYX_HAVE__CRADLE__CorrectBias__calculateOnebp
#define __PYX_HAVE_API__CRADLE__CorrectBias__calculateOnebp
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#include <string.h>
#include <stdlib.h>
#include <stdio.h>
#include "pystate.h"
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#include <omp.h>
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  #define __Pyx_XINCREF(r) Py_XINCREF(r)
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/* PyObjectGetAttrStr.proto */
#if CYTHON_USE_TYPE_SLOTS
static CYTHON_INLINE PyObject* __Pyx_PyObject_GetAttrStr(PyObject* obj, PyObject* attr_name);
#else
#define __Pyx_PyObject_GetAttrStr(o,n) PyObject_GetAttr(o,n)
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/* GetBuiltinName.proto */
static PyObject *__Pyx_GetBuiltinName(PyObject *name);

/* PyDictVersioning.proto */
#if CYTHON_USE_DICT_VERSIONS && CYTHON_USE_TYPE_SLOTS
#define __PYX_DICT_VERSION_INIT  ((PY_UINT64_T) -1)
#define __PYX_GET_DICT_VERSION(dict)  (((PyDictObject*)(dict))->ma_version_tag)
#define __PYX_UPDATE_DICT_CACHE(dict, value, cache_var, version_var)\
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#define __PYX_PY_DICT_LOOKUP_IF_MODIFIED(VAR, DICT, LOOKUP) {\
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static CYTHON_INLINE PY_UINT64_T __Pyx_get_tp_dict_version(PyObject *obj);
static CYTHON_INLINE PY_UINT64_T __Pyx_get_object_dict_version(PyObject *obj);
static CYTHON_INLINE int __Pyx_object_dict_version_matches(PyObject* obj, PY_UINT64_T tp_dict_version, PY_UINT64_T obj_dict_version);
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#define __PYX_GET_DICT_VERSION(dict)  (0)
#define __PYX_UPDATE_DICT_CACHE(dict, value, cache_var, version_var)
#define __PYX_PY_DICT_LOOKUP_IF_MODIFIED(VAR, DICT, LOOKUP)  (VAR) = (LOOKUP);
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/* GetModuleGlobalName.proto */
#if CYTHON_USE_DICT_VERSIONS
#define __Pyx_GetModuleGlobalName(var, name)  {\
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#define __Pyx_GetModuleGlobalNameUncached(var, name)  {\
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static PyObject *__Pyx__GetModuleGlobalName(PyObject *name, PY_UINT64_T *dict_version, PyObject **dict_cached_value);
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#define __Pyx_GetModuleGlobalName(var, name)  (var) = __Pyx__GetModuleGlobalName(name)
#define __Pyx_GetModuleGlobalNameUncached(var, name)  (var) = __Pyx__GetModuleGlobalName(name)
static CYTHON_INLINE PyObject *__Pyx__GetModuleGlobalName(PyObject *name);
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/* PyObjectCall.proto */
#if CYTHON_COMPILING_IN_CPYTHON
static CYTHON_INLINE PyObject* __Pyx_PyObject_Call(PyObject *func, PyObject *arg, PyObject *kw);
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#define __Pyx_PyObject_Call(func, arg, kw) PyObject_Call(func, arg, kw)
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/* PyIntBinop.proto */
#if !CYTHON_COMPILING_IN_PYPY
static PyObject* __Pyx_PyInt_AddObjC(PyObject *op1, PyObject *op2, long intval, int inplace, int zerodivision_check);
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#define __Pyx_PyInt_AddObjC(op1, op2, intval, inplace, zerodivision_check)\
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/* PyIntBinop.proto */
#if !CYTHON_COMPILING_IN_PYPY
static PyObject* __Pyx_PyInt_SubtractObjC(PyObject *op1, PyObject *op2, long intval, int inplace, int zerodivision_check);
#else
#define __Pyx_PyInt_SubtractObjC(op1, op2, intval, inplace, zerodivision_check)\
    (inplace ? PyNumber_InPlaceSubtract(op1, op2) : PyNumber_Subtract(op1, op2))
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/* PyCFunctionFastCall.proto */
#if CYTHON_FAST_PYCCALL
static CYTHON_INLINE PyObject *__Pyx_PyCFunction_FastCall(PyObject *func, PyObject **args, Py_ssize_t nargs);
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#define __Pyx_PyCFunction_FastCall(func, args, nargs)  (assert(0), NULL)
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/* PyFunctionFastCall.proto */
#if CYTHON_FAST_PYCALL
#define __Pyx_PyFunction_FastCall(func, args, nargs)\
    __Pyx_PyFunction_FastCallDict((func), (args), (nargs), NULL)
#if 1 || PY_VERSION_HEX < 0x030600B1
static PyObject *__Pyx_PyFunction_FastCallDict(PyObject *func, PyObject **args, Py_ssize_t nargs, PyObject *kwargs);
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#define __Pyx_PyFunction_FastCallDict(func, args, nargs, kwargs) _PyFunction_FastCallDict(func, args, nargs, kwargs)
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#define __Pyx_BUILD_ASSERT_EXPR(cond)\
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#ifndef Py_MEMBER_SIZE
#define Py_MEMBER_SIZE(type, member) sizeof(((type *)0)->member)
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  #include "frameobject.h"
  #define __Pxy_PyFrame_Initialize_Offsets()\
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/* PyObjectCall2Args.proto */
static CYTHON_UNUSED PyObject* __Pyx_PyObject_Call2Args(PyObject* function, PyObject* arg1, PyObject* arg2);

/* PyObjectCallMethO.proto */
#if CYTHON_COMPILING_IN_CPYTHON
static CYTHON_INLINE PyObject* __Pyx_PyObject_CallMethO(PyObject *func, PyObject *arg);
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/* PyObjectCallOneArg.proto */
static CYTHON_INLINE PyObject* __Pyx_PyObject_CallOneArg(PyObject *func, PyObject *arg);

/* PyIntCompare.proto */
static CYTHON_INLINE PyObject* __Pyx_PyInt_NeObjC(PyObject *op1, PyObject *op2, long intval, long inplace);

/* PyObjectCallNoArg.proto */
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static CYTHON_INLINE PyObject* __Pyx_PyObject_CallNoArg(PyObject *func);
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#define __Pyx_PyObject_CallNoArg(func) __Pyx_PyObject_Call(func, __pyx_empty_tuple, NULL)
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/* PyIntCompare.proto */
static CYTHON_INLINE PyObject* __Pyx_PyInt_EqObjC(PyObject *op1, PyObject *op2, long intval, long inplace);

/* GetItemInt.proto */
#define __Pyx_GetItemInt(o, i, type, is_signed, to_py_func, is_list, wraparound, boundscheck)\
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#define __Pyx_GetItemInt_List(o, i, type, is_signed, to_py_func, is_list, wraparound, boundscheck)\
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static CYTHON_INLINE PyObject *__Pyx_GetItemInt_List_Fast(PyObject *o, Py_ssize_t i,
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#define __Pyx_GetItemInt_Tuple(o, i, type, is_signed, to_py_func, is_list, wraparound, boundscheck)\
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static CYTHON_INLINE PyObject *__Pyx_GetItemInt_Tuple_Fast(PyObject *o, Py_ssize_t i,
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static PyObject *__Pyx_GetItemInt_Generic(PyObject *o, PyObject* j);
static CYTHON_INLINE PyObject *__Pyx_GetItemInt_Fast(PyObject *o, Py_ssize_t i,
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/* SetItemInt.proto */
#define __Pyx_SetItemInt(o, i, v, type, is_signed, to_py_func, is_list, wraparound, boundscheck)\
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static int __Pyx_SetItemInt_Generic(PyObject *o, PyObject *j, PyObject *v);
static CYTHON_INLINE int __Pyx_SetItemInt_Fast(PyObject *o, Py_ssize_t i, PyObject *v,
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/* SliceObject.proto */
static CYTHON_INLINE PyObject* __Pyx_PyObject_GetSlice(
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/* PySequenceContains.proto */
static CYTHON_INLINE int __Pyx_PySequence_ContainsTF(PyObject* item, PyObject* seq, int eq) {
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/* None.proto */
static CYTHON_INLINE void __Pyx_RaiseUnboundLocalError(const char *varname);

/* RaiseTooManyValuesToUnpack.proto */
static CYTHON_INLINE void __Pyx_RaiseTooManyValuesError(Py_ssize_t expected);

/* RaiseNeedMoreValuesToUnpack.proto */
static CYTHON_INLINE void __Pyx_RaiseNeedMoreValuesError(Py_ssize_t index);

/* IterFinish.proto */
static CYTHON_INLINE int __Pyx_IterFinish(void);

/* UnpackItemEndCheck.proto */
static int __Pyx_IternextUnpackEndCheck(PyObject *retval, Py_ssize_t expected);

/* ObjectGetItem.proto */
#if CYTHON_USE_TYPE_SLOTS
static CYTHON_INLINE PyObject *__Pyx_PyObject_GetItem(PyObject *obj, PyObject* key);
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#define __Pyx_PyObject_GetItem(obj, key)  PyObject_GetItem(obj, key)
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/* ListAppend.proto */
#if CYTHON_USE_PYLIST_INTERNALS && CYTHON_ASSUME_SAFE_MACROS
static CYTHON_INLINE int __Pyx_PyList_Append(PyObject* list, PyObject* x) {
    PyListObject* L = (PyListObject*) list;
    Py_ssize_t len = Py_SIZE(list);
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        Py_INCREF(x);
        PyList_SET_ITEM(list, len, x);
        Py_SIZE(list) = len+1;
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    return PyList_Append(list, x);
}
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#define __Pyx_PyList_Append(L,x) PyList_Append(L,x)
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/* RaiseArgTupleInvalid.proto */
static void __Pyx_RaiseArgtupleInvalid(const char* func_name, int exact,
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/* RaiseDoubleKeywords.proto */
static void __Pyx_RaiseDoubleKeywordsError(const char* func_name, PyObject* kw_name);

/* ParseKeywords.proto */
static int __Pyx_ParseOptionalKeywords(PyObject *kwds, PyObject **argnames[],\
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/* DictGetItem.proto */
#if PY_MAJOR_VERSION >= 3 && !CYTHON_COMPILING_IN_PYPY
static PyObject *__Pyx_PyDict_GetItem(PyObject *d, PyObject* key);
#define __Pyx_PyObject_Dict_GetItem(obj, name)\
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#define __Pyx_PyDict_GetItem(d, key) PyObject_GetItem(d, key)
#define __Pyx_PyObject_Dict_GetItem(obj, name)  PyObject_GetItem(obj, name)
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/* pyobject_as_double.proto */
static double __Pyx__PyObject_AsDouble(PyObject* obj);
#if CYTHON_COMPILING_IN_PYPY
#define __Pyx_PyObject_AsDouble(obj)\
(likely(PyFloat_CheckExact(obj)) ? PyFloat_AS_DOUBLE(obj) :\
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 PyFloat_AsDouble(obj) : __Pyx__PyObject_AsDouble(obj))
#else
#define __Pyx_PyObject_AsDouble(obj)\
((likely(PyFloat_CheckExact(obj))) ?\
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/* BufferIndexError.proto */
static void __Pyx_RaiseBufferIndexError(int axis);

/* MemviewSliceInit.proto */
#define __Pyx_BUF_MAX_NDIMS %(BUF_MAX_NDIMS)d
#define __Pyx_MEMVIEW_DIRECT   1
#define __Pyx_MEMVIEW_PTR      2
#define __Pyx_MEMVIEW_FULL     4
#define __Pyx_MEMVIEW_CONTIG   8
#define __Pyx_MEMVIEW_STRIDED  16
#define __Pyx_MEMVIEW_FOLLOW   32
#define __Pyx_IS_C_CONTIG 1
#define __Pyx_IS_F_CONTIG 2
static int __Pyx_init_memviewslice(
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static CYTHON_INLINE int __pyx_add_acquisition_count_locked(
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static CYTHON_INLINE int __pyx_sub_acquisition_count_locked(
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#define __pyx_get_slice_count_pointer(memview) (memview->acquisition_count_aligned_p)
#define __pyx_get_slice_count(memview) (*__pyx_get_slice_count_pointer(memview))
#define __PYX_INC_MEMVIEW(slice, have_gil) __Pyx_INC_MEMVIEW(slice, have_gil, __LINE__)
#define __PYX_XDEC_MEMVIEW(slice, have_gil) __Pyx_XDEC_MEMVIEW(slice, have_gil, __LINE__)
static CYTHON_INLINE void __Pyx_INC_MEMVIEW(__Pyx_memviewslice *, int, int);
static CYTHON_INLINE void __Pyx_XDEC_MEMVIEW(__Pyx_memviewslice *, int, int);

/* IncludeStringH.proto */
#include <string.h>

/* BytesEquals.proto */
static CYTHON_INLINE int __Pyx_PyBytes_Equals(PyObject* s1, PyObject* s2, int equals);

/* UnicodeEquals.proto */
static CYTHON_INLINE int __Pyx_PyUnicode_Equals(PyObject* s1, PyObject* s2, int equals);

/* PyIntBinop.proto */
#if !CYTHON_COMPILING_IN_PYPY
static PyObject* __Pyx_PyInt_SubtractCObj(PyObject *op1, PyObject *op2, long intval, int inplace, int zerodivision_check);
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#define __Pyx_PyInt_SubtractCObj(op1, op2, intval, inplace, zerodivision_check)\
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/* PyIntBinop.proto */
#if !CYTHON_COMPILING_IN_PYPY
static PyObject* __Pyx_PyInt_TrueDivideObjC(PyObject *op1, PyObject *op2, long intval, int inplace, int zerodivision_check);
#else
#define __Pyx_PyInt_TrueDivideObjC(op1, op2, intval, inplace, zerodivision_check)\
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/* PyObjectGetMethod.proto */
static int __Pyx_PyObject_GetMethod(PyObject *obj, PyObject *name, PyObject **method);

/* PyObjectCallMethod1.proto */
static PyObject* __Pyx_PyObject_CallMethod1(PyObject* obj, PyObject* method_name, PyObject* arg);

/* append.proto */
static CYTHON_INLINE int __Pyx_PyObject_Append(PyObject* L, PyObject* x);

/* ListCompAppend.proto */
#if CYTHON_USE_PYLIST_INTERNALS && CYTHON_ASSUME_SAFE_MACROS
static CYTHON_INLINE int __Pyx_ListComp_Append(PyObject* list, PyObject* x) {
    PyListObject* L = (PyListObject*) list;
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        Py_INCREF(x);
        PyList_SET_ITEM(list, len, x);
        Py_SIZE(list) = len+1;
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#define __Pyx_ListComp_Append(L,x) PyList_Append(L,x)
#endif

/* ArgTypeTest.proto */
#define __Pyx_ArgTypeTest(obj, type, none_allowed, name, exact)\
    ((likely((Py_TYPE(obj) == type) | (none_allowed && (obj == Py_None)))) ? 1 :\
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static int __Pyx__ArgTypeTest(PyObject *obj, PyTypeObject *type, const char *name, int exact);

/* PyThreadStateGet.proto */
#if CYTHON_FAST_THREAD_STATE
#define __Pyx_PyThreadState_declare  PyThreadState *__pyx_tstate;
#define __Pyx_PyThreadState_assign  __pyx_tstate = __Pyx_PyThreadState_Current;
#define __Pyx_PyErr_Occurred()  __pyx_tstate->curexc_type
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#define __Pyx_PyThreadState_declare
#define __Pyx_PyThreadState_assign
#define __Pyx_PyErr_Occurred()  PyErr_Occurred()
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/* PyErrFetchRestore.proto */
#if CYTHON_FAST_THREAD_STATE
#define __Pyx_PyErr_Clear() __Pyx_ErrRestore(NULL, NULL, NULL)
#define __Pyx_ErrRestoreWithState(type, value, tb)  __Pyx_ErrRestoreInState(PyThreadState_GET(), type, value, tb)
#define __Pyx_ErrFetchWithState(type, value, tb)    __Pyx_ErrFetchInState(PyThreadState_GET(), type, value, tb)
#define __Pyx_ErrRestore(type, value, tb)  __Pyx_ErrRestoreInState(__pyx_tstate, type, value, tb)
#define __Pyx_ErrFetch(type, value, tb)    __Pyx_ErrFetchInState(__pyx_tstate, type, value, tb)
static CYTHON_INLINE void __Pyx_ErrRestoreInState(PyThreadState *tstate, PyObject *type, PyObject *value, PyObject *tb);
static CYTHON_INLINE void __Pyx_ErrFetchInState(PyThreadState *tstate, PyObject **type, PyObject **value, PyObject **tb);
#if CYTHON_COMPILING_IN_CPYTHON
#define __Pyx_PyErr_SetNone(exc) (Py_INCREF(exc), __Pyx_ErrRestore((exc), NULL, NULL))
#else
#define __Pyx_PyErr_SetNone(exc) PyErr_SetNone(exc)
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#define __Pyx_PyErr_Clear() PyErr_Clear()
#define __Pyx_PyErr_SetNone(exc) PyErr_SetNone(exc)
#define __Pyx_ErrRestoreWithState(type, value, tb)  PyErr_Restore(type, value, tb)
#define __Pyx_ErrFetchWithState(type, value, tb)  PyErr_Fetch(type, value, tb)
#define __Pyx_ErrRestoreInState(tstate, type, value, tb)  PyErr_Restore(type, value, tb)
#define __Pyx_ErrFetchInState(tstate, type, value, tb)  PyErr_Fetch(type, value, tb)
#define __Pyx_ErrRestore(type, value, tb)  PyErr_Restore(type, value, tb)
#define __Pyx_ErrFetch(type, value, tb)  PyErr_Fetch(type, value, tb)
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/* RaiseException.proto */
static void __Pyx_Raise(PyObject *type, PyObject *value, PyObject *tb, PyObject *cause);

/* StrEquals.proto */
#if PY_MAJOR_VERSION >= 3
#define __Pyx_PyString_Equals __Pyx_PyUnicode_Equals
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#define __Pyx_PyString_Equals __Pyx_PyBytes_Equals
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/* Module declarations from 'CRADLE.CorrectBias.calculateOnebp' */
static PyTypeObject *__pyx_array_type = 0;
static PyTypeObject *__pyx_MemviewEnum_type = 0;
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static PyObject *__pyx_f_6CRADLE_11CorrectBias_14calculateOnebp_calculateContinuousFrag(PyObject *, PyObject *, PyObject *, PyObject *, PyObject *, PyObject *, PyObject *, int __pyx_skip_dispatch); /*proto*/
static PyObject *__pyx_f_6CRADLE_11CorrectBias_14calculateOnebp_calculateDiscreteFrag(PyObject *, PyObject *, PyObject *, PyObject *, PyObject *, PyObject *, PyObject *, int __pyx_skip_dispatch); /*proto*/
static PyObject *__pyx_f_6CRADLE_11CorrectBias_14calculateOnebp_calculateTrainCovariates(PyObject *, int __pyx_skip_dispatch); /*proto*/
static PyObject *__pyx_f_6CRADLE_11CorrectBias_14calculateOnebp_calculateTaskCovariates(PyObject *, int __pyx_skip_dispatch); /*proto*/
static PyObject *__pyx_f_6CRADLE_11CorrectBias_14calculateOnebp_performRegression(PyObject *, int __pyx_skip_dispatch); /*proto*/
static PyObject *__pyx_f_6CRADLE_11CorrectBias_14calculateOnebp_memoryView(PyObject *, int __pyx_skip_dispatch); /*proto*/
static PyObject *__pyx_f_6CRADLE_11CorrectBias_14calculateOnebp_makeMatrixContinuousFragTrain(PyObject *, PyObject *, PyObject *, int __pyx_skip_dispatch); /*proto*/
static PyObject *__pyx_f_6CRADLE_11CorrectBias_14calculateOnebp_makeMatrixContinuousFrag(PyObject *, PyObject *, PyObject *, int __pyx_skip_dispatch); /*proto*/
static PyObject *__pyx_f_6CRADLE_11CorrectBias_14calculateOnebp_makeMatrixDiscreteFrag(PyObject *, PyObject *, PyObject *, int __pyx_skip_dispatch); /*proto*/
static PyObject *__pyx_f_6CRADLE_11CorrectBias_14calculateOnebp_find5merProb(PyObject *, int __pyx_skip_dispatch); /*proto*/
static PyObject *__pyx_f_6CRADLE_11CorrectBias_14calculateOnebp_edit5merProb(PyObject *, PyObject *, PyObject *, int __pyx_skip_dispatch); /*proto*/
static PyObject *__pyx_f_6CRADLE_11CorrectBias_14calculateOnebp_findComple5merProb(PyObject *, int __pyx_skip_dispatch); /*proto*/
static PyObject *__pyx_f_6CRADLE_11CorrectBias_14calculateOnebp_editComple5merProb(PyObject *, PyObject *, PyObject *, int __pyx_skip_dispatch); /*proto*/
static PyObject *__pyx_f_6CRADLE_11CorrectBias_14calculateOnebp_findStartGibbs(PyObject *, PyObject *, int __pyx_skip_dispatch); /*proto*/
static PyObject *__pyx_f_6CRADLE_11CorrectBias_14calculateOnebp_editStartGibbs(PyObject *, PyObject *, PyObject *, int __pyx_skip_dispatch); /*proto*/
static PyObject *__pyx_f_6CRADLE_11CorrectBias_14calculateOnebp_convertGibbs(PyObject *, int __pyx_skip_dispatch); /*proto*/
static PyObject *__pyx_f_6CRADLE_11CorrectBias_14calculateOnebp_correctReadCount(PyObject *, PyObject *, PyObject *, PyObject *, PyObject *, PyObject *, int __pyx_skip_dispatch); /*proto*/
static PyObject *__pyx_f_6CRADLE_11CorrectBias_14calculateOnebp_selectIdx(PyObject *, PyObject *, PyObject *, PyObject *, PyObject *, PyObject *, int __pyx_skip_dispatch); /*proto*/
static PyObject *__pyx_f_6CRADLE_11CorrectBias_14calculateOnebp_writeBedFile(PyObject *, PyObject *, PyObject *, PyObject *, int __pyx_skip_dispatch); /*proto*/
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static int __pyx_memoryview_slice_memviewslice(__Pyx_memviewslice *, Py_ssize_t, Py_ssize_t, Py_ssize_t, int, int, int *, Py_ssize_t, Py_ssize_t, Py_ssize_t, int, int, int, int); /*proto*/
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static char __pyx_get_best_slice_order(__Pyx_memviewslice *, int); /*proto*/
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static void copy_strided_to_strided(__Pyx_memviewslice *, __Pyx_memviewslice *, int, size_t); /*proto*/
static Py_ssize_t __pyx_memoryview_slice_get_size(__Pyx_memviewslice *, int); /*proto*/
static Py_ssize_t __pyx_fill_contig_strides_array(Py_ssize_t *, Py_ssize_t *, Py_ssize_t, int, char); /*proto*/
static void *__pyx_memoryview_copy_data_to_temp(__Pyx_memviewslice *, __Pyx_memviewslice *, char, int); /*proto*/
static int __pyx_memoryview_err_extents(int, Py_ssize_t, Py_ssize_t); /*proto*/
static int __pyx_memoryview_err_dim(PyObject *, char *, int); /*proto*/
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static void __pyx_memoryview_slice_assign_scalar(__Pyx_memviewslice *, int, size_t, void *, int); /*proto*/
static void __pyx_memoryview__slice_assign_scalar(char *, Py_ssize_t *, Py_ssize_t *, int, size_t, void *); /*proto*/
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static __Pyx_TypeInfo __Pyx_TypeInfo_double = { "double", NULL, sizeof(double), { 0 }, 0, 'R', 0, 0 };
#define __Pyx_MODULE_NAME "CRADLE.CorrectBias.calculateOnebp"
extern int __pyx_module_is_main_CRADLE__CorrectBias__calculateOnebp;
int __pyx_module_is_main_CRADLE__CorrectBias__calculateOnebp = 0;

/* Implementation of 'CRADLE.CorrectBias.calculateOnebp' */
static PyObject *__pyx_builtin_range;
static PyObject *__pyx_builtin_open;
static PyObject *__pyx_builtin_ValueError;
static PyObject *__pyx_builtin_MemoryError;
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static const char __pyx_k_id[] = "id";
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static const char __pyx_k_log[] = "log";
static const char __pyx_k_max[] = "max";
static const char __pyx_k_min[] = "min";
static const char __pyx_k_nan[] = "nan";
static const char __pyx_k_new[] = "__new__";
static const char __pyx_k_obj[] = "obj";
static const char __pyx_k_plt[] = "plt";
static const char __pyx_k_png[] = ".png";
static const char __pyx_k_seq[] = "seq";
static const char __pyx_k_sum[] = "sum";
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static const char __pyx_k_use[] = "use";
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static const char __pyx_k_KMER[] = "KMER";
static const char __pyx_k_PROT[] = "PROT";
static const char __pyx_k_axis[] = "axis";
static const char __pyx_k_base[] = "base";
static const char __pyx_k_dict[] = "__dict__";
static const char __pyx_k_gzip[] = "gzip";
static const char __pyx_k_h5py[] = "h5py";
static const char __pyx_k_hdf5[] = ".hdf5";
static const char __pyx_k_link[] = "link";
static const char __pyx_k_main[] = "__main__";
static const char __pyx_k_math[] = "math";
static const char __pyx_k_mean[] = "mean";
static const char __pyx_k_mode[] = "mode";
static const char __pyx_k_name[] = "name";
static const char __pyx_k_ndim[] = "ndim";
static const char __pyx_k_ones[] = "ones";
static const char __pyx_k_open[] = "open";
static const char __pyx_k_pack[] = "pack";
static const char __pyx_k_plot[] = "plot";
static const char __pyx_k_size[] = "size";
static const char __pyx_k_step[] = "step";
static const char __pyx_k_stop[] = "stop";
static const char __pyx_k_test[] = "__test__";
static const char __pyx_k_text[] = "text";
static const char __pyx_k_time[] = "time";
static const char __pyx_k_type[] = "type";
static const char __pyx_k_vari[] = "vari";
static const char __pyx_k_xlim[] = "xlim";
static const char __pyx_k_ylim[] = "ylim";
static const char __pyx_k_ASCII[] = "ASCII";
static const char __pyx_k_GIBBS[] = "GIBBS";
static const char __pyx_k_GQUAD[] = "GQUAD";
static const char __pyx_k_N_MGW[] = "N_MGW";
static const char __pyx_k_PARA1[] = "PARA1";
static const char __pyx_k_PARA2[] = "PARA2";
static const char __pyx_k_SHEAR[] = "SHEAR";
static const char __pyx_k_alpha[] = "alpha";
static const char __pyx_k_array[] = "array";
static const char __pyx_k_class[] = "__class__";
static const char __pyx_k_close[] = "close";
static const char __pyx_k_color[] = "color";
static const char __pyx_k_dtype[] = "dtype";
static const char __pyx_k_equal[] = "equal";
static const char __pyx_k_error[] = "error";
static const char __pyx_k_finfo[] = "finfo";
static const char __pyx_k_fit_2[] = "/fit_";
static const char __pyx_k_flags[] = "flags";
static const char __pyx_k_isnan[] = "isnan";
static const char __pyx_k_links[] = "links";
static const char __pyx_k_nBins[] = "nBins";
static const char __pyx_k_numpy[] = "numpy";
static const char __pyx_k_power[] = "power";
static const char __pyx_k_range[] = "range";
static const char __pyx_k_round[] = "round";
static const char __pyx_k_scipy[] = "scipy";
static const char __pyx_k_shape[] = "shape";
static const char __pyx_k_split[] = "split";
static const char __pyx_k_start[] = "start";
static const char __pyx_k_stats[] = "stats";
static const char __pyx_k_upper[] = "upper";
static const char __pyx_k_where[] = "where";
static const char __pyx_k_write[] = "write";
static const char __pyx_k_zeros[] = "zeros";
static const char __pyx_k_HIGHRC[] = "HIGHRC";
static const char __pyx_k_MAX_TM[] = "MAX_TM";
static const char __pyx_k_MIN_TM[] = "MIN_TM";
static const char __pyx_k_N_PROT[] = "N_PROT";
static const char __pyx_k_append[] = "append";
static const char __pyx_k_arange[] = "arange";
static const char __pyx_k_astype[] = "astype";
static const char __pyx_k_binEnd[] = "binEnd";
static const char __pyx_k_center[] = "center";
static const char __pyx_k_choice[] = "choice";
static const char __pyx_k_chromo[] = "chromo";
static const char __pyx_k_chroms[] = "chroms";
static const char __pyx_k_delete[] = "delete";
static const char __pyx_k_encode[] = "encode";
static const char __pyx_k_extend[] = "extend";
static const char __pyx_k_family[] = "family";
static const char __pyx_k_format[] = "format";
static const char __pyx_k_genmod[] = "genmod";
static const char __pyx_k_ignore[] = "ignore";
static const char __pyx_k_import[] = "__import__";
static const char __pyx_k_marker[] = "marker";
static const char __pyx_k_name_2[] = "__name__";
static const char __pyx_k_nanmax[] = "nanmax";
static const char __pyx_k_params[] = "params";
static const char __pyx_k_pickle[] = "pickle";
static const char __pyx_k_py2bit[] = "py2bit";
static const char __pyx_k_random[] = "random";
static const char __pyx_k_reduce[] = "__reduce__";
static const char __pyx_k_remove[] = "remove";
static const char __pyx_k_rsplit[] = "rsplit";
static const char __pyx_k_seqLen[] = "seqLen";
static const char __pyx_k_struct[] = "struct";
static const char __pyx_k_suffix[] = "suffix";
static const char __pyx_k_tolist[] = "tolist";
static const char __pyx_k_unpack[] = "unpack";
static const char __pyx_k_update[] = "update";
static const char __pyx_k_values[] = "values";
static const char __pyx_k_xlabel[] = "xlabel";
static const char __pyx_k_ylabel[] = "ylabel";
static const char __pyx_k_BINSIZE[] = "BINSIZE";
static const char __pyx_k_COEFEXP[] = "COEFEXP";
static const char __pyx_k_ENTROPY[] = "ENTROPY";
static const char __pyx_k_FRAGLEN[] = "FRAGLEN";
static const char __pyx_k_MAPFILE[] = "MAPFILE";
static const char __pyx_k_N_GIBBS[] = "N_GIBBS";
static const char __pyx_k_Poisson[] = "Poisson";
static const char __pyx_k_asarray[] = "asarray";
static const char __pyx_k_float32[] = "float32";
static const char __pyx_k_float64[] = "float64";
static const char __pyx_k_fortran[] = "fortran";
static const char __pyx_k_lastBin[] = "lastBin";
static const char __pyx_k_memview[] = "memview";
static const char __pyx_k_nanmean[] = "nanmean";
static const char __pyx_k_newBase[] = "newBase";
static const char __pyx_k_oldBase[] = "oldBase";
static const char __pyx_k_pastMer[] = "pastMer";
static const char __pyx_k_replace[] = "replace";
static const char __pyx_k_savefig[] = "savefig";
static const char __pyx_k_COEFCTRL[] = "COEFCTRL";
static const char __pyx_k_Ellipsis[] = "Ellipsis";
static const char __pyx_k_binStart[] = "binStart";
static const char __pyx_k_corrcoef[] = "corrcoef";
static const char __pyx_k_families[] = "families";
static const char __pyx_k_getstate[] = "__getstate__";
static const char __pyx_k_itemsize[] = "itemsize";
static const char __pyx_k_newDimer[] = "newDimer";
static const char __pyx_k_observed[] = "observed";
static const char __pyx_k_oldDimer[] = "oldDimer";
static const char __pyx_k_pyBigWig[] = "pyBigWig";
static const char __pyx_k_pyx_type[] = "__pyx_type";
static const char __pyx_k_sequence[] = "sequence";
static const char __pyx_k_setstate[] = "__setstate__";
static const char __pyx_k_tempfile[] = "tempfile";
static const char __pyx_k_warnings[] = "warnings";
static const char __pyx_k_EXPBW_NUM[] = "EXPBW_NUM";
static const char __pyx_k_EXPSCALER[] = "EXPSCALER";
static const char __pyx_k_GQAUDFILE[] = "GQAUDFILE";
static const char __pyx_k_GQAUD_MAX[] = "GQAUD_MAX";
static const char __pyx_k_TypeError[] = "TypeError";
static const char __pyx_k_enumerate[] = "enumerate";
static const char __pyx_k_predicted[] = "predicted";
static const char __pyx_k_pyx_state[] = "__pyx_state";
static const char __pyx_k_reduce_ex[] = "__reduce_ex__";
static const char __pyx_k_regionEnd[] = "regionEnd";
static const char __pyx_k_COVARI_NUM[] = "COVARI_NUM";
static const char __pyx_k_CTRLBW_NUM[] = "CTRLBW_NUM";
static const char __pyx_k_CTRLSCALER[] = "CTRLSCALER";
static const char __pyx_k_IndexError[] = "IndexError";
static const char __pyx_k_OUTPUT_DIR[] = "OUTPUT_DIR";
static const char __pyx_k_SAMPLE_NUM[] = "SAMPLE_NUM";
static const char __pyx_k_ValueError[] = "ValueError";
static const char __pyx_k_adjustable[] = "adjustable";
static const char __pyx_k_lastBinEnd[] = "lastBinEnd";
static const char __pyx_k_matplotlib[] = "matplotlib";
static const char __pyx_k_pyx_result[] = "__pyx_result";
static const char __pyx_k_pyx_vtable[] = "__pyx_vtable__";
static const char __pyx_k_set_aspect[] = "set_aspect";
static const char __pyx_k_tempStarts[] = "tempStarts";
static const char __pyx_k_EXPBW_NAMES[] = "EXPBW_NAMES";
static const char __pyx_k_FILTERVALUE[] = "FILTERVALUE";
static const char __pyx_k_MemoryError[] = "MemoryError";
static const char __pyx_k_PickleError[] = "PickleError";
static const char __pyx_k_analysisEnd[] = "analysisEnd";
static const char __pyx_k_compression[] = "compression";
static const char __pyx_k_intersect1d[] = "intersect1d";
static const char __pyx_k_regionStart[] = "regionStart";
static const char __pyx_k_subfileName[] = "subfileName";
static const char __pyx_k_CTRLBW_NAMES[] = "CTRLBW_NAMES";
static const char __pyx_k_fittedvalues[] = "fittedvalues";
static const char __pyx_k_lastBinStart[] = "lastBinStart";
static const char __pyx_k_pyx_checksum[] = "__pyx_checksum";
static const char __pyx_k_stringsource[] = "stringsource";
static const char __pyx_k_analysisStart[] = "analysisStart";
static const char __pyx_k_pyx_getbuffer[] = "__pyx_getbuffer";
static const char __pyx_k_reduce_cython[] = "__reduce_cython__";
static const char __pyx_k_COEFEXP_HIGHRC[] = "COEFEXP_HIGHRC";
static const char __pyx_k_covariFileName[] = "covariFileName";
static const char __pyx_k_create_dataset[] = "create_dataset";
static const char __pyx_k_filterwarnings[] = "filterwarnings";
static const char __pyx_k_pastStartGibbs[] = "pastStartGibbs";
static const char __pyx_k_tempSignalvals[] = "tempSignalvals";
static const char __pyx_k_COEFCTRL_HIGHRC[] = "COEFCTRL_HIGHRC";
static const char __pyx_k_View_MemoryView[] = "View.MemoryView";
static const char __pyx_k_allocate_buffer[] = "allocate_buffer";
static const char __pyx_k_dtype_is_object[] = "dtype_is_object";
static const char __pyx_k_pyx_PickleError[] = "__pyx_PickleError";
static const char __pyx_k_setstate_cython[] = "__setstate_cython__";
static const char __pyx_k_statsmodels_api[] = "statsmodels.api";
static const char __pyx_k_matplotlib_pyplot[] = "matplotlib.pyplot";
static const char __pyx_k_pyx_unpickle_Enum[] = "__pyx_unpickle_Enum";
static const char __pyx_k_CRADLE_CorrectBias[] = "CRADLE.CorrectBias";
static const char __pyx_k_NamedTemporaryFile[] = "NamedTemporaryFile";
static const char __pyx_k_cline_in_traceback[] = "cline_in_traceback";
static const char __pyx_k_strided_and_direct[] = "<strided and direct>";
static const char __pyx_k_Mean_of_empty_slice[] = "Mean of empty slice";
static const char __pyx_k_strided_and_indirect[] = "<strided and indirect>";
static const char __pyx_k_contiguous_and_direct[] = "<contiguous and direct>";
static const char __pyx_k_MemoryView_of_r_object[] = "<MemoryView of %r object>";
static const char __pyx_k_MemoryView_of_r_at_0x_x[] = "<MemoryView of %r at 0x%x>";
static const char __pyx_k_contiguous_and_indirect[] = "<contiguous and indirect>";
static const char __pyx_k_Cannot_index_with_type_s[] = "Cannot index with type '%s'";
static const char __pyx_k_All_NaN_slice_encountered[] = "All-NaN slice encountered";
static const char __pyx_k_Invalid_shape_in_axis_d_d[] = "Invalid shape in axis %d: %d.";
static const char __pyx_k_itemsize_0_for_cython_array[] = "itemsize <= 0 for cython.array";
static const char __pyx_k_unable_to_allocate_array_data[] = "unable to allocate array data.";
static const char __pyx_k_strided_and_direct_or_indirect[] = "<strided and direct or indirect>";
static const char __pyx_k_Buffer_view_does_not_expose_stri[] = "Buffer view does not expose strides";
static const char __pyx_k_Can_only_create_a_buffer_that_is[] = "Can only create a buffer that is contiguous in memory.";
static const char __pyx_k_Cannot_assign_to_read_only_memor[] = "Cannot assign to read-only memoryview";
static const char __pyx_k_Cannot_create_writable_memory_vi[] = "Cannot create writable memory view from read-only memoryview";
static const char __pyx_k_Empty_shape_tuple_for_cython_arr[] = "Empty shape tuple for cython.array";
static const char __pyx_k_Incompatible_checksums_s_vs_0xb0[] = "Incompatible checksums (%s vs 0xb068931 = (name))";
static const char __pyx_k_Indirect_dimensions_not_supporte[] = "Indirect dimensions not supported";
static const char __pyx_k_Invalid_mode_expected_c_or_fortr[] = "Invalid mode, expected 'c' or 'fortran', got %s";
static const char __pyx_k_Out_of_bounds_on_buffer_access_a[] = "Out of bounds on buffer access (axis %d)";
static const char __pyx_k_Unable_to_convert_item_to_object[] = "Unable to convert item to object";
static const char __pyx_k_got_differing_extents_in_dimensi[] = "got differing extents in dimension %d (got %d and %d)";
static const char __pyx_k_no_default___reduce___due_to_non[] = "no default __reduce__ due to non-trivial __cinit__";
static const char __pyx_k_unable_to_allocate_shape_and_str[] = "unable to allocate shape and strides.";
static PyObject *__pyx_n_u_A;
static PyObject *__pyx_n_s_ASCII;
static PyObject *__pyx_n_u_Agg;
static PyObject *__pyx_kp_u_All_NaN_slice_encountered;
static PyObject *__pyx_n_s_BINSIZE;
static PyObject *__pyx_kp_s_Buffer_view_does_not_expose_stri;
static PyObject *__pyx_n_u_C;
static PyObject *__pyx_n_s_COEFCTRL;
static PyObject *__pyx_n_s_COEFCTRL_HIGHRC;
static PyObject *__pyx_n_s_COEFEXP;
static PyObject *__pyx_n_s_COEFEXP_HIGHRC;
static PyObject *__pyx_n_s_COVARI_NUM;
static PyObject *__pyx_n_s_CRADLE_CorrectBias;
static PyObject *__pyx_n_s_CTRLBW_NAMES;
static PyObject *__pyx_n_s_CTRLBW_NUM;
static PyObject *__pyx_n_s_CTRLSCALER;
static PyObject *__pyx_kp_s_Can_only_create_a_buffer_that_is;
static PyObject *__pyx_kp_s_Cannot_assign_to_read_only_memor;
static PyObject *__pyx_kp_s_Cannot_create_writable_memory_vi;
static PyObject *__pyx_kp_s_Cannot_index_with_type_s;
static PyObject *__pyx_n_s_ENTROPY;
static PyObject *__pyx_n_s_EXPBW_NAMES;
static PyObject *__pyx_n_s_EXPBW_NUM;
static PyObject *__pyx_n_s_EXPSCALER;
static PyObject *__pyx_n_s_Ellipsis;
static PyObject *__pyx_kp_s_Empty_shape_tuple_for_cython_arr;
static PyObject *__pyx_n_s_FA;
static PyObject *__pyx_n_s_FILTERVALUE;
static PyObject *__pyx_n_s_FRAGLEN;
static PyObject *__pyx_n_s_File;
static PyObject *__pyx_n_u_G;
static PyObject *__pyx_n_s_GIBBS;
static PyObject *__pyx_n_s_GLM;
static PyObject *__pyx_n_s_GQAUDFILE;
static PyObject *__pyx_n_s_GQAUD_MAX;
static PyObject *__pyx_n_s_GQUAD;
static PyObject *__pyx_n_s_HIGHRC;
static PyObject *__pyx_kp_s_Incompatible_checksums_s_vs_0xb0;
static PyObject *__pyx_n_s_IndexError;
static PyObject *__pyx_kp_s_Indirect_dimensions_not_supporte;
static PyObject *__pyx_kp_s_Invalid_mode_expected_c_or_fortr;
static PyObject *__pyx_kp_s_Invalid_shape_in_axis_d_d;
static PyObject *__pyx_n_s_KMER;
static PyObject *__pyx_n_s_MAP;
static PyObject *__pyx_n_s_MAPFILE;
static PyObject *__pyx_n_s_MAX_TM;
static PyObject *__pyx_n_s_MGW;
static PyObject *__pyx_n_s_MIN_TM;
static PyObject *__pyx_kp_u_Mean_of_empty_slice;
static PyObject *__pyx_n_s_MemoryError;
static PyObject *__pyx_kp_s_MemoryView_of_r_at_0x_x;
static PyObject *__pyx_kp_s_MemoryView_of_r_object;
static PyObject *__pyx_n_u_N;
static PyObject *__pyx_n_s_N_GIBBS;
static PyObject *__pyx_n_s_N_MGW;
static PyObject *__pyx_n_s_N_PROT;
static PyObject *__pyx_n_s_NamedTemporaryFile;
static PyObject *__pyx_n_b_O;
static PyObject *__pyx_n_s_OUTPUT_DIR;
static PyObject *__pyx_kp_s_Out_of_bounds_on_buffer_access_a;
static PyObject *__pyx_n_s_PARA1;
static PyObject *__pyx_n_s_PARA2;
static PyObject *__pyx_n_s_PCR;
static PyObject *__pyx_n_s_PROT;
static PyObject *__pyx_n_s_PickleError;
static PyObject *__pyx_n_s_Poisson;
static PyObject *__pyx_n_s_SAMPLE_NUM;
static PyObject *__pyx_n_s_SHEAR;
static PyObject *__pyx_n_u_T;
static PyObject *__pyx_n_s_TypeError;
static PyObject *__pyx_kp_s_Unable_to_convert_item_to_object;
static PyObject *__pyx_n_s_ValueError;
static PyObject *__pyx_n_s_View_MemoryView;
static PyObject *__pyx_n_u_X;
static PyObject *__pyx_n_u_Y;
static PyObject *__pyx_kp_u__13;
static PyObject *__pyx_kp_u__14;
static PyObject *__pyx_n_s__33;
static PyObject *__pyx_kp_u__5;
static PyObject *__pyx_kp_u__6;
static PyObject *__pyx_n_u_a;
static PyObject *__pyx_n_s_adjustable;
static PyObject *__pyx_n_s_allocate_buffer;
static PyObject *__pyx_n_s_alpha;
static PyObject *__pyx_n_s_analysisEnd;
static PyObject *__pyx_n_s_analysisStart;
static PyObject *__pyx_n_s_append;
static PyObject *__pyx_n_s_arange;
static PyObject *__pyx_n_s_array;
static PyObject *__pyx_n_s_asarray;
static PyObject *__pyx_n_s_astype;
static PyObject *__pyx_n_s_axis;
static PyObject *__pyx_n_s_base;
static PyObject *__pyx_kp_u_bed;
static PyObject *__pyx_n_s_binEnd;
static PyObject *__pyx_n_s_binStart;
static PyObject *__pyx_n_u_box;
static PyObject *__pyx_n_s_c;
static PyObject *__pyx_n_u_c;
static PyObject *__pyx_n_u_center;
static PyObject *__pyx_n_s_choice;
static PyObject *__pyx_n_s_chromo;
static PyObject *__pyx_n_s_chroms;
static PyObject *__pyx_n_s_class;
static PyObject *__pyx_n_s_clf;
static PyObject *__pyx_n_s_cline_in_traceback;
static PyObject *__pyx_n_s_close;
static PyObject *__pyx_n_s_color;
static PyObject *__pyx_n_s_compression;
static PyObject *__pyx_kp_s_contiguous_and_direct;
static PyObject *__pyx_kp_s_contiguous_and_indirect;
static PyObject *__pyx_n_s_corrcoef;
static PyObject *__pyx_n_s_covariFileName;
static PyObject *__pyx_n_s_create_dataset;
static PyObject *__pyx_n_s_delete;
static PyObject *__pyx_n_s_dict;
static PyObject *__pyx_n_s_dir;
static PyObject *__pyx_n_s_dtype;
static PyObject *__pyx_n_s_dtype_is_object;
static PyObject *__pyx_n_s_encode;
static PyObject *__pyx_n_s_enumerate;
static PyObject *__pyx_n_u_equal;
static PyObject *__pyx_n_s_error;
static PyObject *__pyx_n_s_exp;
static PyObject *__pyx_n_s_extend;
static PyObject *__pyx_n_u_f;
static PyObject *__pyx_n_s_families;
static PyObject *__pyx_n_s_family;
static PyObject *__pyx_n_s_filterwarnings;
static PyObject *__pyx_n_s_finfo;
static PyObject *__pyx_n_s_fit;
static PyObject *__pyx_kp_u_fit_2;
static PyObject *__pyx_n_s_fittedvalues;
static PyObject *__pyx_n_s_flags;
static PyObject *__pyx_n_s_float32;
static PyObject *__pyx_n_s_float64;
static PyObject *__pyx_n_s_format;
static PyObject *__pyx_n_s_fortran;
static PyObject *__pyx_n_u_fortran;
static PyObject *__pyx_n_u_g;
static PyObject *__pyx_n_s_gc;
static PyObject *__pyx_n_s_gca;
static PyObject *__pyx_n_s_genmod;
static PyObject *__pyx_n_s_getstate;
static PyObject *__pyx_kp_s_got_differing_extents_in_dimensi;
static PyObject *__pyx_n_u_gzip;
static PyObject *__pyx_n_s_h5py;
static PyObject *__pyx_n_s_ha;
static PyObject *__pyx_kp_u_hdf5;
static PyObject *__pyx_n_s_id;
static PyObject *__pyx_n_u_ignore;
static PyObject *__pyx_n_s_import;
static PyObject *__pyx_n_s_intersect1d;
static PyObject *__pyx_n_s_isnan;
static PyObject *__pyx_n_s_itemsize;
static PyObject *__pyx_kp_s_itemsize_0_for_cython_array;
static PyObject *__pyx_kp_u_k;
static PyObject *__pyx_n_s_lastBin;
static PyObject *__pyx_n_s_lastBinEnd;
static PyObject *__pyx_n_s_lastBinStart;
static PyObject *__pyx_n_s_link;
static PyObject *__pyx_n_s_links;
static PyObject *__pyx_n_s_log;
static PyObject *__pyx_n_s_main;
static PyObject *__pyx_n_s_marker;
static PyObject *__pyx_n_s_math;
static PyObject *__pyx_n_s_matplotlib;
static PyObject *__pyx_n_s_matplotlib_pyplot;
static PyObject *__pyx_n_s_max;
static PyObject *__pyx_n_u_mean;
static PyObject *__pyx_n_s_memview;
static PyObject *__pyx_n_s_min;
static PyObject *__pyx_n_s_mode;
static PyObject *__pyx_n_s_nBins;
static PyObject *__pyx_n_s_name;
static PyObject *__pyx_n_s_name_2;
static PyObject *__pyx_n_s_nan;
static PyObject *__pyx_n_s_nanmax;
static PyObject *__pyx_n_s_nanmean;
static PyObject *__pyx_n_s_ndim;
static PyObject *__pyx_n_s_new;
static PyObject *__pyx_n_s_newBase;
static PyObject *__pyx_n_s_newDimer;
static PyObject *__pyx_kp_s_no_default___reduce___due_to_non;
static PyObject *__pyx_n_s_np;
static PyObject *__pyx_n_s_numpy;
static PyObject *__pyx_n_s_obj;
static PyObject *__pyx_n_u_observed;
static PyObject *__pyx_n_s_oldBase;
static PyObject *__pyx_n_s_oldDimer;
static PyObject *__pyx_n_s_ones;
static PyObject *__pyx_n_s_open;
static PyObject *__pyx_n_s_os;
static PyObject *__pyx_n_s_pack;
static PyObject *__pyx_n_s_params;
static PyObject *__pyx_n_s_pastMer;
static PyObject *__pyx_n_s_pastStartGibbs;
static PyObject *__pyx_n_s_pickle;
static PyObject *__pyx_n_s_plot;
static PyObject *__pyx_n_s_plt;
static PyObject *__pyx_kp_u_png;
static PyObject *__pyx_n_s_power;
static PyObject *__pyx_n_u_predicted;
static PyObject *__pyx_n_s_py2bit;
static PyObject *__pyx_n_s_pyBigWig;
static PyObject *__pyx_n_s_pyx_PickleError;
static PyObject *__pyx_n_s_pyx_checksum;
static PyObject *__pyx_n_s_pyx_getbuffer;
static PyObject *__pyx_n_s_pyx_result;
static PyObject *__pyx_n_s_pyx_state;
static PyObject *__pyx_n_s_pyx_type;
static PyObject *__pyx_n_s_pyx_unpickle_Enum;
static PyObject *__pyx_n_s_pyx_vtable;
static PyObject *__pyx_n_u_r;
static PyObject *__pyx_n_s_random;
static PyObject *__pyx_n_s_range;
static PyObject *__pyx_n_s_reduce;
static PyObject *__pyx_n_s_reduce_cython;
static PyObject *__pyx_n_s_reduce_ex;
static PyObject *__pyx_n_s_regionEnd;
static PyObject *__pyx_n_s_regionStart;
static PyObject *__pyx_n_s_remove;
static PyObject *__pyx_n_s_replace;
static PyObject *__pyx_n_s_round;
static PyObject *__pyx_n_s_rsplit;
static PyObject *__pyx_n_u_s;
static PyObject *__pyx_n_s_savefig;
static PyObject *__pyx_n_s_scipy;
static PyObject *__pyx_n_s_seq;
static PyObject *__pyx_n_s_seqLen;
static PyObject *__pyx_n_s_sequence;
static PyObject *__pyx_n_s_set_aspect;
static PyObject *__pyx_n_s_setstate;
static PyObject *__pyx_n_s_setstate_cython;
static PyObject *__pyx_n_s_shape;
static PyObject *__pyx_n_s_size;
static PyObject *__pyx_n_s_sm;
static PyObject *__pyx_n_s_split;
static PyObject *__pyx_n_s_start;
static PyObject *__pyx_n_s_stats;
static PyObject *__pyx_n_s_statsmodels_api;
static PyObject *__pyx_n_s_step;
static PyObject *__pyx_n_s_stop;
static PyObject *__pyx_kp_s_strided_and_direct;
static PyObject *__pyx_kp_s_strided_and_direct_or_indirect;
static PyObject *__pyx_kp_s_strided_and_indirect;
static PyObject *__pyx_kp_s_stringsource;
static PyObject *__pyx_n_s_struct;
static PyObject *__pyx_n_s_subfileName;
static PyObject *__pyx_n_s_suffix;
static PyObject *__pyx_n_s_sum;
static PyObject *__pyx_n_s_sys;
static PyObject *__pyx_n_u_t;
static PyObject *__pyx_n_s_tempSignalvals;
static PyObject *__pyx_n_s_tempStarts;
static PyObject *__pyx_n_s_tempfile;
static PyObject *__pyx_n_s_test;
static PyObject *__pyx_n_s_text;
static PyObject *__pyx_n_s_time;
static PyObject *__pyx_n_s_tolist;
static PyObject *__pyx_n_s_type;
static PyObject *__pyx_kp_s_unable_to_allocate_array_data;
static PyObject *__pyx_kp_s_unable_to_allocate_shape_and_str;
static PyObject *__pyx_n_s_unpack;
static PyObject *__pyx_n_s_update;
static PyObject *__pyx_n_s_upper;
static PyObject *__pyx_n_s_use;
static PyObject *__pyx_n_s_va;
static PyObject *__pyx_n_s_values;
static PyObject *__pyx_n_s_vari;
static PyObject *__pyx_n_u_w;
static PyObject *__pyx_kp_u_w_t;
static PyObject *__pyx_n_s_warnings;
static PyObject *__pyx_n_s_where;
static PyObject *__pyx_n_s_write;
static PyObject *__pyx_n_s_xlabel;
static PyObject *__pyx_n_s_xlim;
static PyObject *__pyx_n_s_ylabel;
static PyObject *__pyx_n_s_ylim;
static PyObject *__pyx_n_s_zeros;
static PyObject *__pyx_pf_6CRADLE_11CorrectBias_14calculateOnebp_calculateContinuousFrag(CYTHON_UNUSED PyObject *__pyx_self, PyObject *__pyx_v_chromo, PyObject *__pyx_v_analysisStart, PyObject *__pyx_v_analysisEnd, PyObject *__pyx_v_binStart, PyObject *__pyx_v_binEnd, PyObject *__pyx_v_nBins, PyObject *__pyx_v_lastBin); /* proto */
static PyObject *__pyx_pf_6CRADLE_11CorrectBias_14calculateOnebp_2calculateDiscreteFrag(CYTHON_UNUSED PyObject *__pyx_self, PyObject *__pyx_v_chromo, PyObject *__pyx_v_analysisStart, PyObject *__pyx_v_analysisEnd, PyObject *__pyx_v_binStart, PyObject *__pyx_v_binEnd, PyObject *__pyx_v_nBins, PyObject *__pyx_v_lastBin); /* proto */
static PyObject *__pyx_pf_6CRADLE_11CorrectBias_14calculateOnebp_4calculateTrainCovariates(CYTHON_UNUSED PyObject *__pyx_self, PyObject *__pyx_v_args); /* proto */
static PyObject *__pyx_pf_6CRADLE_11CorrectBias_14calculateOnebp_6calculateTaskCovariates(CYTHON_UNUSED PyObject *__pyx_self, PyObject *__pyx_v_args); /* proto */
static PyObject *__pyx_pf_6CRADLE_11CorrectBias_14calculateOnebp_8performRegression(CYTHON_UNUSED PyObject *__pyx_self, PyObject *__pyx_v_covariFiles); /* proto */
static PyObject *__pyx_pf_6CRADLE_11CorrectBias_14calculateOnebp_10memoryView(CYTHON_UNUSED PyObject *__pyx_self, PyObject *__pyx_v_value); /* proto */
static PyObject *__pyx_pf_6CRADLE_11CorrectBias_14calculateOnebp_12makeMatrixContinuousFragTrain(CYTHON_UNUSED PyObject *__pyx_self, PyObject *__pyx_v_binStart, PyObject *__pyx_v_binEnd, PyObject *__pyx_v_nBins); /* proto */
static PyObject *__pyx_pf_6CRADLE_11CorrectBias_14calculateOnebp_14makeMatrixContinuousFrag(CYTHON_UNUSED PyObject *__pyx_self, PyObject *__pyx_v_binStart, PyObject *__pyx_v_binEnd, PyObject *__pyx_v_nBins); /* proto */
static PyObject *__pyx_pf_6CRADLE_11CorrectBias_14calculateOnebp_16makeMatrixDiscreteFrag(CYTHON_UNUSED PyObject *__pyx_self, PyObject *__pyx_v_binStart, PyObject *__pyx_v_binEnd, PyObject *__pyx_v_nBins); /* proto */
static PyObject *__pyx_pf_6CRADLE_11CorrectBias_14calculateOnebp_18find5merProb(CYTHON_UNUSED PyObject *__pyx_self, PyObject *__pyx_v_mer5); /* proto */
static PyObject *__pyx_pf_6CRADLE_11CorrectBias_14calculateOnebp_20edit5merProb(CYTHON_UNUSED PyObject *__pyx_self, PyObject *__pyx_v_pastMer, PyObject *__pyx_v_oldBase, PyObject *__pyx_v_newBase); /* proto */
static PyObject *__pyx_pf_6CRADLE_11CorrectBias_14calculateOnebp_22findComple5merProb(CYTHON_UNUSED PyObject *__pyx_self, PyObject *__pyx_v_mer5); /* proto */
static PyObject *__pyx_pf_6CRADLE_11CorrectBias_14calculateOnebp_24editComple5merProb(CYTHON_UNUSED PyObject *__pyx_self, PyObject *__pyx_v_pastMer, PyObject *__pyx_v_oldBase, PyObject *__pyx_v_newBase); /* proto */
static PyObject *__pyx_pf_6CRADLE_11CorrectBias_14calculateOnebp_26findStartGibbs(CYTHON_UNUSED PyObject *__pyx_self, PyObject *__pyx_v_seq, PyObject *__pyx_v_seqLen); /* proto */
static PyObject *__pyx_pf_6CRADLE_11CorrectBias_14calculateOnebp_28editStartGibbs(CYTHON_UNUSED PyObject *__pyx_self, PyObject *__pyx_v_oldDimer, PyObject *__pyx_v_newDimer, PyObject *__pyx_v_pastStartGibbs); /* proto */
static PyObject *__pyx_pf_6CRADLE_11CorrectBias_14calculateOnebp_30convertGibbs(CYTHON_UNUSED PyObject *__pyx_self, PyObject *__pyx_v_gibbs); /* proto */
static PyObject *__pyx_pf_6CRADLE_11CorrectBias_14calculateOnebp_32correctReadCount(CYTHON_UNUSED PyObject *__pyx_self, PyObject *__pyx_v_covariFileName, PyObject *__pyx_v_chromo, PyObject *__pyx_v_analysisStart, PyObject *__pyx_v_analysisEnd, PyObject *__pyx_v_lastBin, PyObject *__pyx_v_nBins); /* proto */
static PyObject *__pyx_pf_6CRADLE_11CorrectBias_14calculateOnebp_34selectIdx(CYTHON_UNUSED PyObject *__pyx_self, PyObject *__pyx_v_chromo, PyObject *__pyx_v_regionStart, PyObject *__pyx_v_regionEnd, PyObject *__pyx_v_lastBinStart, PyObject *__pyx_v_lastBinEnd, PyObject *__pyx_v_nBins); /* proto */
static PyObject *__pyx_pf_6CRADLE_11CorrectBias_14calculateOnebp_36writeBedFile(CYTHON_UNUSED PyObject *__pyx_self, PyObject *__pyx_v_subfileName, PyObject *__pyx_v_tempStarts, PyObject *__pyx_v_tempSignalvals, PyObject *__pyx_v_analysisEnd); /* proto */
static int __pyx_array___pyx_pf_15View_dot_MemoryView_5array___cinit__(struct __pyx_array_obj *__pyx_v_self, PyObject *__pyx_v_shape, Py_ssize_t __pyx_v_itemsize, PyObject *__pyx_v_format, PyObject *__pyx_v_mode, int __pyx_v_allocate_buffer); /* proto */
static int __pyx_array___pyx_pf_15View_dot_MemoryView_5array_2__getbuffer__(struct __pyx_array_obj *__pyx_v_self, Py_buffer *__pyx_v_info, int __pyx_v_flags); /* proto */
static void __pyx_array___pyx_pf_15View_dot_MemoryView_5array_4__dealloc__(struct __pyx_array_obj *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_15View_dot_MemoryView_5array_7memview___get__(struct __pyx_array_obj *__pyx_v_self); /* proto */
static Py_ssize_t __pyx_array___pyx_pf_15View_dot_MemoryView_5array_6__len__(struct __pyx_array_obj *__pyx_v_self); /* proto */
static PyObject *__pyx_array___pyx_pf_15View_dot_MemoryView_5array_8__getattr__(struct __pyx_array_obj *__pyx_v_self, PyObject *__pyx_v_attr); /* proto */
static PyObject *__pyx_array___pyx_pf_15View_dot_MemoryView_5array_10__getitem__(struct __pyx_array_obj *__pyx_v_self, PyObject *__pyx_v_item); /* proto */
static int __pyx_array___pyx_pf_15View_dot_MemoryView_5array_12__setitem__(struct __pyx_array_obj *__pyx_v_self, PyObject *__pyx_v_item, PyObject *__pyx_v_value); /* proto */
static PyObject *__pyx_pf___pyx_array___reduce_cython__(CYTHON_UNUSED struct __pyx_array_obj *__pyx_v_self); /* proto */
static PyObject *__pyx_pf___pyx_array_2__setstate_cython__(CYTHON_UNUSED struct __pyx_array_obj *__pyx_v_self, CYTHON_UNUSED PyObject *__pyx_v___pyx_state); /* proto */
static int __pyx_MemviewEnum___pyx_pf_15View_dot_MemoryView_4Enum___init__(struct __pyx_MemviewEnum_obj *__pyx_v_self, PyObject *__pyx_v_name); /* proto */
static PyObject *__pyx_MemviewEnum___pyx_pf_15View_dot_MemoryView_4Enum_2__repr__(struct __pyx_MemviewEnum_obj *__pyx_v_self); /* proto */
static PyObject *__pyx_pf___pyx_MemviewEnum___reduce_cython__(struct __pyx_MemviewEnum_obj *__pyx_v_self); /* proto */
static PyObject *__pyx_pf___pyx_MemviewEnum_2__setstate_cython__(struct __pyx_MemviewEnum_obj *__pyx_v_self, PyObject *__pyx_v___pyx_state); /* proto */
static int __pyx_memoryview___pyx_pf_15View_dot_MemoryView_10memoryview___cinit__(struct __pyx_memoryview_obj *__pyx_v_self, PyObject *__pyx_v_obj, int __pyx_v_flags, int __pyx_v_dtype_is_object); /* proto */
static void __pyx_memoryview___pyx_pf_15View_dot_MemoryView_10memoryview_2__dealloc__(struct __pyx_memoryview_obj *__pyx_v_self); /* proto */
static PyObject *__pyx_memoryview___pyx_pf_15View_dot_MemoryView_10memoryview_4__getitem__(struct __pyx_memoryview_obj *__pyx_v_self, PyObject *__pyx_v_index); /* proto */
static int __pyx_memoryview___pyx_pf_15View_dot_MemoryView_10memoryview_6__setitem__(struct __pyx_memoryview_obj *__pyx_v_self, PyObject *__pyx_v_index, PyObject *__pyx_v_value); /* proto */
static int __pyx_memoryview___pyx_pf_15View_dot_MemoryView_10memoryview_8__getbuffer__(struct __pyx_memoryview_obj *__pyx_v_self, Py_buffer *__pyx_v_info, int __pyx_v_flags); /* proto */
static PyObject *__pyx_pf_15View_dot_MemoryView_10memoryview_1T___get__(struct __pyx_memoryview_obj *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_15View_dot_MemoryView_10memoryview_4base___get__(struct __pyx_memoryview_obj *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_15View_dot_MemoryView_10memoryview_5shape___get__(struct __pyx_memoryview_obj *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_15View_dot_MemoryView_10memoryview_7strides___get__(struct __pyx_memoryview_obj *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_15View_dot_MemoryView_10memoryview_10suboffsets___get__(struct __pyx_memoryview_obj *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_15View_dot_MemoryView_10memoryview_4ndim___get__(struct __pyx_memoryview_obj *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_15View_dot_MemoryView_10memoryview_8itemsize___get__(struct __pyx_memoryview_obj *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_15View_dot_MemoryView_10memoryview_6nbytes___get__(struct __pyx_memoryview_obj *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_15View_dot_MemoryView_10memoryview_4size___get__(struct __pyx_memoryview_obj *__pyx_v_self); /* proto */
static Py_ssize_t __pyx_memoryview___pyx_pf_15View_dot_MemoryView_10memoryview_10__len__(struct __pyx_memoryview_obj *__pyx_v_self); /* proto */
static PyObject *__pyx_memoryview___pyx_pf_15View_dot_MemoryView_10memoryview_12__repr__(struct __pyx_memoryview_obj *__pyx_v_self); /* proto */
static PyObject *__pyx_memoryview___pyx_pf_15View_dot_MemoryView_10memoryview_14__str__(struct __pyx_memoryview_obj *__pyx_v_self); /* proto */
static PyObject *__pyx_memoryview___pyx_pf_15View_dot_MemoryView_10memoryview_16is_c_contig(struct __pyx_memoryview_obj *__pyx_v_self); /* proto */
static PyObject *__pyx_memoryview___pyx_pf_15View_dot_MemoryView_10memoryview_18is_f_contig(struct __pyx_memoryview_obj *__pyx_v_self); /* proto */
static PyObject *__pyx_memoryview___pyx_pf_15View_dot_MemoryView_10memoryview_20copy(struct __pyx_memoryview_obj *__pyx_v_self); /* proto */
static PyObject *__pyx_memoryview___pyx_pf_15View_dot_MemoryView_10memoryview_22copy_fortran(struct __pyx_memoryview_obj *__pyx_v_self); /* proto */
static PyObject *__pyx_pf___pyx_memoryview___reduce_cython__(CYTHON_UNUSED struct __pyx_memoryview_obj *__pyx_v_self); /* proto */
static PyObject *__pyx_pf___pyx_memoryview_2__setstate_cython__(CYTHON_UNUSED struct __pyx_memoryview_obj *__pyx_v_self, CYTHON_UNUSED PyObject *__pyx_v___pyx_state); /* proto */
static void __pyx_memoryviewslice___pyx_pf_15View_dot_MemoryView_16_memoryviewslice___dealloc__(struct __pyx_memoryviewslice_obj *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_15View_dot_MemoryView_16_memoryviewslice_4base___get__(struct __pyx_memoryviewslice_obj *__pyx_v_self); /* proto */
static PyObject *__pyx_pf___pyx_memoryviewslice___reduce_cython__(CYTHON_UNUSED struct __pyx_memoryviewslice_obj *__pyx_v_self); /* proto */
static PyObject *__pyx_pf___pyx_memoryviewslice_2__setstate_cython__(CYTHON_UNUSED struct __pyx_memoryviewslice_obj *__pyx_v_self, CYTHON_UNUSED PyObject *__pyx_v___pyx_state); /* proto */
static PyObject *__pyx_pf_15View_dot_MemoryView___pyx_unpickle_Enum(CYTHON_UNUSED PyObject *__pyx_self, PyObject *__pyx_v___pyx_type, long __pyx_v___pyx_checksum, PyObject *__pyx_v___pyx_state); /* proto */
static PyObject *__pyx_tp_new_array(PyTypeObject *t, PyObject *a, PyObject *k); /*proto*/
static PyObject *__pyx_tp_new_Enum(PyTypeObject *t, PyObject *a, PyObject *k); /*proto*/
static PyObject *__pyx_tp_new_memoryview(PyTypeObject *t, PyObject *a, PyObject *k); /*proto*/
static PyObject *__pyx_tp_new__memoryviewslice(PyTypeObject *t, PyObject *a, PyObject *k); /*proto*/
static PyObject *__pyx_float_0_0;
static PyObject *__pyx_float_0_01;
static PyObject *__pyx_int_0;
static PyObject *__pyx_int_1;
static PyObject *__pyx_int_2;
static PyObject *__pyx_int_3;
static PyObject *__pyx_int_4;
static PyObject *__pyx_int_10;
static PyObject *__pyx_int_25;
static PyObject *__pyx_int_50000;
static PyObject *__pyx_int_184977713;
static PyObject *__pyx_int_neg_1;
static PyObject *__pyx_int_neg_5;
static PyObject *__pyx_int_neg_6;
static PyObject *__pyx_tuple_;
static PyObject *__pyx_slice__3;
static PyObject *__pyx_slice__8;
static PyObject *__pyx_tuple__2;
static PyObject *__pyx_tuple__4;
static PyObject *__pyx_tuple__7;
static PyObject *__pyx_tuple__9;
static PyObject *__pyx_slice__11;
static PyObject *__pyx_slice__12;
static PyObject *__pyx_slice__29;
static PyObject *__pyx_tuple__10;
static PyObject *__pyx_tuple__15;
static PyObject *__pyx_tuple__16;
static PyObject *__pyx_tuple__17;
static PyObject *__pyx_tuple__18;
static PyObject *__pyx_tuple__19;
static PyObject *__pyx_tuple__20;
static PyObject *__pyx_tuple__21;
static PyObject *__pyx_tuple__22;
static PyObject *__pyx_tuple__23;
static PyObject *__pyx_tuple__24;
static PyObject *__pyx_tuple__25;
static PyObject *__pyx_tuple__26;
static PyObject *__pyx_tuple__27;
static PyObject *__pyx_tuple__28;
static PyObject *__pyx_tuple__30;
static PyObject *__pyx_tuple__31;
static PyObject *__pyx_tuple__32;
static PyObject *__pyx_tuple__34;
static PyObject *__pyx_tuple__35;
static PyObject *__pyx_tuple__36;
static PyObject *__pyx_tuple__37;
static PyObject *__pyx_tuple__38;
static PyObject *__pyx_tuple__39;
static PyObject *__pyx_tuple__40;
static PyObject *__pyx_codeobj__41;
/* Late includes */

/* "CRADLE/CorrectBias/calculateOnebp.pyx":22
 * from CRADLE.CorrectBias import vari
 * 
 * cpdef calculateContinuousFrag(chromo, analysisStart, analysisEnd, binStart, binEnd, nBins, lastBin):             # <<<<<<<<<<<<<<
 * 
 * 	warnings.filterwarnings('ignore', r'All-NaN slice encountered')
 */

static PyObject *__pyx_pw_6CRADLE_11CorrectBias_14calculateOnebp_1calculateContinuousFrag(PyObject *__pyx_self, PyObject *__pyx_args, PyObject *__pyx_kwds); /*proto*/
static PyObject *__pyx_f_6CRADLE_11CorrectBias_14calculateOnebp_calculateContinuousFrag(PyObject *__pyx_v_chromo, PyObject *__pyx_v_analysisStart, PyObject *__pyx_v_analysisEnd, PyObject *__pyx_v_binStart, PyObject *__pyx_v_binEnd, PyObject *__pyx_v_nBins, PyObject *__pyx_v_lastBin, CYTHON_UNUSED int __pyx_skip_dispatch) {
  PyObject *__pyx_v_fragStart = NULL;
  PyObject *__pyx_v_fragEnd = NULL;
  PyObject *__pyx_v_shearStart = NULL;
  PyObject *__pyx_v_shearEnd = NULL;
  PyObject *__pyx_v_faFile = NULL;
  PyObject *__pyx_v_chromoEnd = NULL;
  PyObject *__pyx_v_leftValue = NULL;
  PyObject *__pyx_v_analysisEndModified = NULL;
  PyObject *__pyx_v_result = NULL;
  PyObject *__pyx_v_fa = NULL;
  PyObject *__pyx_v_mapFile = NULL;
  PyObject *__pyx_v_mapValue = NULL;
  PyObject *__pyx_v_mapValueView = NULL;
  PyObject *__pyx_v_gquadFile = NULL;
  PyObject *__pyx_v_gquadValue = NULL;
  Py_ssize_t __pyx_v_i;
  PyObject *__pyx_v_gquadView = NULL;
  long __pyx_v_startIdx;
  PyObject *__pyx_v_endIdx = NULL;
  PyObject *__pyx_v_pastMer1 = NULL;
  PyObject *__pyx_v_pastMer2 = NULL;
  long __pyx_v_pastStartGibbs;
  PyObject *__pyx_v_resultStartIdx = NULL;
  PyObject *__pyx_v_resultEndIdx = NULL;
  PyObject *__pyx_v_covariFileTemp = NULL;
  PyObject *__pyx_v_covariFileName = NULL;
  PyObject *__pyx_v_f = NULL;
  PyObject *__pyx_v_covariFile = NULL;
  PyObject *__pyx_v_idx = NULL;
  PyObject *__pyx_v_covariIdx = NULL;
  PyObject *__pyx_v_covariIdxPtr = NULL;
  PyObject *__pyx_v_mer1 = NULL;
  PyObject *__pyx_v_mgwIdx = NULL;
  PyObject *__pyx_v_protIdx = NULL;
  PyObject *__pyx_v_fragEndIdx = NULL;
  PyObject *__pyx_v_mer2 = NULL;
  PyObject *__pyx_v_add1 = NULL;
  PyObject *__pyx_v_add2 = NULL;
  PyObject *__pyx_v_faIdx = NULL;
  CYTHON_UNUSED PyObject *__pyx_v_startGibbs = NULL;
  PyObject *__pyx_v_gibbs = NULL;
  PyObject *__pyx_v_oldDimer = NULL;
  PyObject *__pyx_v_newDimer = NULL;
  PyObject *__pyx_v_annealIdx = NULL;
  PyObject *__pyx_v_denatureIdx = NULL;
  PyObject *__pyx_v_map1 = NULL;
  PyObject *__pyx_v_map2 = NULL;
  PyObject *__pyx_v_mapIdx = NULL;
  PyObject *__pyx_v_gquadIdx = NULL;
  PyObject *__pyx_v_thisFragStart = NULL;
  PyObject *__pyx_v_thisFragEnd = NULL;
  PyObject *__pyx_v_maxBinPos = NULL;
  PyObject *__pyx_v_numPoppedPos = NULL;
  PyObject *__pyx_v_line = NULL;
  PyObject *__pyx_v_covariPos = NULL;
  PyObject *__pyx_v_pos = NULL;
  PyObject *__pyx_r = NULL;
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  PyObject *__pyx_t_2 = NULL;
  PyObject *__pyx_t_3 = NULL;
  PyObject *__pyx_t_4 = NULL;
  int __pyx_t_5;
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 *     if isinstance(memview, _memoryviewslice):             # <<<<<<<<<<<<<<
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 */
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 * 
 *     if isinstance(memview, _memoryviewslice):
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 *                                     memviewsliceobj.to_object_func,
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 *                                     memviewsliceobj.to_dtype_func,
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 *     if isinstance(memview, _memoryviewslice):
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 *                                     memviewsliceobj.to_object_func,
 *                                     memviewsliceobj.to_dtype_func,
 */
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 *             new_ndim += 1
 * 
 *     if isinstance(memview, _memoryviewslice):             # <<<<<<<<<<<<<<
 *         return memoryview_fromslice(dst, new_ndim,
 *                                     memviewsliceobj.to_object_func,
 */
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  /* "View.MemoryView":782
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 *                                     memview.dtype_is_object)
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 */
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 * 
 * 
 */
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 *     else:
 *         return memoryview_fromslice(dst, new_ndim, NULL, NULL,             # <<<<<<<<<<<<<<
 *                                     memview.dtype_is_object)
 * 
 */
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 * 
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 *     cdef int new_ndim = 0, suboffset_dim = -1, dim
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 */

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/* "View.MemoryView":807
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 * cdef int slice_memviewslice(             # <<<<<<<<<<<<<<
 *         __Pyx_memviewslice *dst,
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 */

static int __pyx_memoryview_slice_memviewslice(__Pyx_memviewslice *__pyx_v_dst, Py_ssize_t __pyx_v_shape, Py_ssize_t __pyx_v_stride, Py_ssize_t __pyx_v_suboffset, int __pyx_v_dim, int __pyx_v_new_ndim, int *__pyx_v_suboffset_dim, Py_ssize_t __pyx_v_start, Py_ssize_t __pyx_v_stop, Py_ssize_t __pyx_v_step, int __pyx_v_have_start, int __pyx_v_have_stop, int __pyx_v_have_step, int __pyx_v_is_slice) {
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  int __pyx_r;
  int __pyx_t_1;
  int __pyx_t_2;
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 *     cdef bint negative_step
 * 
 *     if not is_slice:             # <<<<<<<<<<<<<<
 * 
 *         if start < 0:
 */
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 *         if start < 0:             # <<<<<<<<<<<<<<
 *             start += shape
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 */
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 * 
 *         if start < 0:
 *             start += shape             # <<<<<<<<<<<<<<
 *         if not 0 <= start < shape:
 *             _err_dim(IndexError, "Index out of bounds (axis %d)", dim)
 */
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 *     if not is_slice:
 * 
 *         if start < 0:             # <<<<<<<<<<<<<<
 *             start += shape
 *         if not 0 <= start < shape:
 */
    }

    /* "View.MemoryView":831
 *         if start < 0:
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 *         if not 0 <= start < shape:             # <<<<<<<<<<<<<<
 *             _err_dim(IndexError, "Index out of bounds (axis %d)", dim)
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 */
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      /* "View.MemoryView":832
 *             start += shape
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 *     else:
 * 
 */
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      /* "View.MemoryView":831
 *         if start < 0:
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 *             _err_dim(IndexError, "Index out of bounds (axis %d)", dim)
 *     else:
 */
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    /* "View.MemoryView":827
 *     cdef bint negative_step
 * 
 *     if not is_slice:             # <<<<<<<<<<<<<<
 * 
 *         if start < 0:
 */
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  /* "View.MemoryView":835
 *     else:
 * 
 *         negative_step = have_step != 0 and step < 0             # <<<<<<<<<<<<<<
 * 
 *         if have_step and step == 0:
 */
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    /* "View.MemoryView":837
 *         negative_step = have_step != 0 and step < 0
 * 
 *         if have_step and step == 0:             # <<<<<<<<<<<<<<
 *             _err_dim(ValueError, "Step may not be zero (axis %d)", dim)
 * 
 */
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      /* "View.MemoryView":838
 * 
 *         if have_step and step == 0:
 *             _err_dim(ValueError, "Step may not be zero (axis %d)", dim)             # <<<<<<<<<<<<<<
 * 
 * 
 */
      __pyx_t_3 = __pyx_memoryview_err_dim(__pyx_builtin_ValueError, ((char *)"Step may not be zero (axis %d)"), __pyx_v_dim); if (unlikely(__pyx_t_3 == ((int)-1))) __PYX_ERR(1, 838, __pyx_L1_error)

      /* "View.MemoryView":837
 *         negative_step = have_step != 0 and step < 0
 * 
 *         if have_step and step == 0:             # <<<<<<<<<<<<<<
 *             _err_dim(ValueError, "Step may not be zero (axis %d)", dim)
 * 
 */
    }

    /* "View.MemoryView":841
 * 
 * 
 *         if have_start:             # <<<<<<<<<<<<<<
 *             if start < 0:
 *                 start += shape
 */
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      /* "View.MemoryView":842
 * 
 *         if have_start:
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 *                 start += shape
 *                 if start < 0:
 */
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        /* "View.MemoryView":843
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 *                 if start < 0:
 *                     start = 0
 */
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        /* "View.MemoryView":844
 *             if start < 0:
 *                 start += shape
 *                 if start < 0:             # <<<<<<<<<<<<<<
 *                     start = 0
 *             elif start >= shape:
 */
        __pyx_t_2 = ((__pyx_v_start < 0) != 0);
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          /* "View.MemoryView":845
 *                 start += shape
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 *                     start = 0             # <<<<<<<<<<<<<<
 *             elif start >= shape:
 *                 if negative_step:
 */
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          /* "View.MemoryView":844
 *             if start < 0:
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 *                 if start < 0:             # <<<<<<<<<<<<<<
 *                     start = 0
 *             elif start >= shape:
 */
        }

        /* "View.MemoryView":842
 * 
 *         if have_start:
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 *                 start += shape
 *                 if start < 0:
 */
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      /* "View.MemoryView":846
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 *                     start = 0
 *             elif start >= shape:             # <<<<<<<<<<<<<<
 *                 if negative_step:
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 */
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        /* "View.MemoryView":847
 *                     start = 0
 *             elif start >= shape:
 *                 if negative_step:             # <<<<<<<<<<<<<<
 *                     start = shape - 1
 *                 else:
 */
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        if (__pyx_t_2) {

          /* "View.MemoryView":848
 *             elif start >= shape:
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 *                     start = shape - 1             # <<<<<<<<<<<<<<
 *                 else:
 *                     start = shape
 */
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          /* "View.MemoryView":847
 *                     start = 0
 *             elif start >= shape:
 *                 if negative_step:             # <<<<<<<<<<<<<<
 *                     start = shape - 1
 *                 else:
 */
          goto __pyx_L14;
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        /* "View.MemoryView":850
 *                     start = shape - 1
 *                 else:
 *                     start = shape             # <<<<<<<<<<<<<<
 *         else:
 *             if negative_step:
 */
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        /* "View.MemoryView":846
 *                 if start < 0:
 *                     start = 0
 *             elif start >= shape:             # <<<<<<<<<<<<<<
 *                 if negative_step:
 *                     start = shape - 1
 */
      }
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      /* "View.MemoryView":841
 * 
 * 
 *         if have_start:             # <<<<<<<<<<<<<<
 *             if start < 0:
 *                 start += shape
 */
      goto __pyx_L11;
    }

    /* "View.MemoryView":852
 *                     start = shape
 *         else:
 *             if negative_step:             # <<<<<<<<<<<<<<
 *                 start = shape - 1
 *             else:
 */
    /*else*/ {
      __pyx_t_2 = (__pyx_v_negative_step != 0);
      if (__pyx_t_2) {

        /* "View.MemoryView":853
 *         else:
 *             if negative_step:
 *                 start = shape - 1             # <<<<<<<<<<<<<<
 *             else:
 *                 start = 0
 */
        __pyx_v_start = (__pyx_v_shape - 1);

        /* "View.MemoryView":852
 *                     start = shape
 *         else:
 *             if negative_step:             # <<<<<<<<<<<<<<
 *                 start = shape - 1
 *             else:
 */
        goto __pyx_L15;
      }

      /* "View.MemoryView":855
 *                 start = shape - 1
 *             else:
 *                 start = 0             # <<<<<<<<<<<<<<
 * 
 *         if have_stop:
 */
      /*else*/ {
        __pyx_v_start = 0;
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      __pyx_L15:;
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    /* "View.MemoryView":857
 *                 start = 0
 * 
 *         if have_stop:             # <<<<<<<<<<<<<<
 *             if stop < 0:
 *                 stop += shape
 */
    __pyx_t_2 = (__pyx_v_have_stop != 0);
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      /* "View.MemoryView":858
 * 
 *         if have_stop:
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 *                 stop += shape
 *                 if stop < 0:
 */
      __pyx_t_2 = ((__pyx_v_stop < 0) != 0);
      if (__pyx_t_2) {

        /* "View.MemoryView":859
 *         if have_stop:
 *             if stop < 0:
 *                 stop += shape             # <<<<<<<<<<<<<<
 *                 if stop < 0:
 *                     stop = 0
 */
        __pyx_v_stop = (__pyx_v_stop + __pyx_v_shape);

        /* "View.MemoryView":860
 *             if stop < 0:
 *                 stop += shape
 *                 if stop < 0:             # <<<<<<<<<<<<<<
 *                     stop = 0
 *             elif stop > shape:
 */
        __pyx_t_2 = ((__pyx_v_stop < 0) != 0);
        if (__pyx_t_2) {

          /* "View.MemoryView":861
 *                 stop += shape
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 *                     stop = 0             # <<<<<<<<<<<<<<
 *             elif stop > shape:
 *                 stop = shape
 */
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          /* "View.MemoryView":860
 *             if stop < 0:
 *                 stop += shape
 *                 if stop < 0:             # <<<<<<<<<<<<<<
 *                     stop = 0
 *             elif stop > shape:
 */
        }

        /* "View.MemoryView":858
 * 
 *         if have_stop:
 *             if stop < 0:             # <<<<<<<<<<<<<<
 *                 stop += shape
 *                 if stop < 0:
 */
        goto __pyx_L17;
      }

      /* "View.MemoryView":862
 *                 if stop < 0:
 *                     stop = 0
 *             elif stop > shape:             # <<<<<<<<<<<<<<
 *                 stop = shape
 *         else:
 */
      __pyx_t_2 = ((__pyx_v_stop > __pyx_v_shape) != 0);
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        /* "View.MemoryView":863
 *                     stop = 0
 *             elif stop > shape:
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 *         else:
 *             if negative_step:
 */
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        /* "View.MemoryView":862
 *                 if stop < 0:
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 *                 stop = shape
 *         else:
 */
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      /* "View.MemoryView":857
 *                 start = 0
 * 
 *         if have_stop:             # <<<<<<<<<<<<<<
 *             if stop < 0:
 *                 stop += shape
 */
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 *                 stop = shape
 *         else:
 *             if negative_step:             # <<<<<<<<<<<<<<
 *                 stop = -1
 *             else:
 */
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        /* "View.MemoryView":866
 *         else:
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 *             else:
 *                 stop = shape
 */
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        /* "View.MemoryView":865
 *                 stop = shape
 *         else:
 *             if negative_step:             # <<<<<<<<<<<<<<
 *                 stop = -1
 *             else:
 */
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 *                 stop = -1
 *             else:
 *                 stop = shape             # <<<<<<<<<<<<<<
 * 
 *         if not have_step:
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 *     if isinstance(memview, _memoryviewslice):             # <<<<<<<<<<<<<<
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 * 
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 * cdef Py_ssize_t abs_py_ssize_t(Py_ssize_t arg) nogil:
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 * cdef Py_ssize_t abs_py_ssize_t(Py_ssize_t arg) nogil:
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 * 
 * cdef Py_ssize_t abs_py_ssize_t(Py_ssize_t arg) nogil:             # <<<<<<<<<<<<<<
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/* "View.MemoryView":1116
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 */
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 *     for i in range(ndim - 1, -1, -1):
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  /* "View.MemoryView":1124
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 *     for i in range(ndim - 1, -1, -1):             # <<<<<<<<<<<<<<
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    /* "View.MemoryView":1125
 * 
 *     for i in range(ndim - 1, -1, -1):
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      /* "View.MemoryView":1126
 *     for i in range(ndim - 1, -1, -1):
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 * 
 */
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      /* "View.MemoryView":1127
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 *     for i in range(ndim):
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      /* "View.MemoryView":1125
 * 
 *     for i in range(ndim - 1, -1, -1):
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 *             c_stride = mslice.strides[i]
 *             break
 */
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  /* "View.MemoryView":1129
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 * 
 *     for i in range(ndim):             # <<<<<<<<<<<<<<
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    /* "View.MemoryView":1130
 * 
 *     for i in range(ndim):
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 */
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      /* "View.MemoryView":1131
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 * 
 */
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      /* "View.MemoryView":1132
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 *     if abs_py_ssize_t(c_stride) <= abs_py_ssize_t(f_stride):
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      /* "View.MemoryView":1130
 * 
 *     for i in range(ndim):
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 */
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/* "View.MemoryView":1140
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static void _copy_strided_to_strided(char *__pyx_v_src_data, Py_ssize_t *__pyx_v_src_strides, char *__pyx_v_dst_data, Py_ssize_t *__pyx_v_dst_strides, Py_ssize_t *__pyx_v_src_shape, Py_ssize_t *__pyx_v_dst_shape, int __pyx_v_ndim, size_t __pyx_v_itemsize) {
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  Py_ssize_t __pyx_v_dst_stride;
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  int __pyx_t_2;
  int __pyx_t_3;
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  Py_ssize_t __pyx_t_5;
  Py_ssize_t __pyx_t_6;

  /* "View.MemoryView":1147
 * 
 *     cdef Py_ssize_t i
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 *     cdef Py_ssize_t dst_extent = dst_shape[0]
 *     cdef Py_ssize_t src_stride = src_strides[0]
 */
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  /* "View.MemoryView":1148
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 *     cdef Py_ssize_t dst_extent = dst_shape[0]             # <<<<<<<<<<<<<<
 *     cdef Py_ssize_t src_stride = src_strides[0]
 *     cdef Py_ssize_t dst_stride = dst_strides[0]
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  /* "View.MemoryView":1149
 *     cdef Py_ssize_t src_extent = src_shape[0]
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 *     cdef Py_ssize_t src_stride = src_strides[0]             # <<<<<<<<<<<<<<
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 */
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  /* "View.MemoryView":1150
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 *     if ndim == 1:
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  /* "View.MemoryView":1152
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 * 
 *     if ndim == 1:
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      /* "View.MemoryView":1155
 *        if (src_stride > 0 and dst_stride > 0 and
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 *        else:
 *            for i in range(dst_extent):
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      /* "View.MemoryView":1153
 * 
 *     if ndim == 1:
 *        if (src_stride > 0 and dst_stride > 0 and             # <<<<<<<<<<<<<<
 *            <size_t> src_stride == itemsize == <size_t> dst_stride):
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    /* "View.MemoryView":1157
 *            memcpy(dst_data, src_data, itemsize * dst_extent)
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        /* "View.MemoryView":1158
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 *                memcpy(dst_data, src_data, itemsize)             # <<<<<<<<<<<<<<
 *                src_data += src_stride
 *                dst_data += dst_stride
 */
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        /* "View.MemoryView":1159
 *            for i in range(dst_extent):
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 *                dst_data += dst_stride
 *     else:
 */
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        /* "View.MemoryView":1160
 *                memcpy(dst_data, src_data, itemsize)
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 *                dst_data += dst_stride             # <<<<<<<<<<<<<<
 *     else:
 *         for i in range(dst_extent):
 */
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 *     cdef Py_ssize_t dst_stride = dst_strides[0]
 * 
 *     if ndim == 1:             # <<<<<<<<<<<<<<
 *        if (src_stride > 0 and dst_stride > 0 and
 *            <size_t> src_stride == itemsize == <size_t> dst_stride):
 */
    goto __pyx_L3;
  }

  /* "View.MemoryView":1162
 *                dst_data += dst_stride
 *     else:
 *         for i in range(dst_extent):             # <<<<<<<<<<<<<<
 *             _copy_strided_to_strided(src_data, src_strides + 1,
 *                                      dst_data, dst_strides + 1,
 */
  /*else*/ {
    __pyx_t_4 = __pyx_v_dst_extent;
    __pyx_t_5 = __pyx_t_4;
    for (__pyx_t_6 = 0; __pyx_t_6 < __pyx_t_5; __pyx_t_6+=1) {
      __pyx_v_i = __pyx_t_6;

      /* "View.MemoryView":1163
 *     else:
 *         for i in range(dst_extent):
 *             _copy_strided_to_strided(src_data, src_strides + 1,             # <<<<<<<<<<<<<<
 *                                      dst_data, dst_strides + 1,
 *                                      src_shape + 1, dst_shape + 1,
 */
      _copy_strided_to_strided(__pyx_v_src_data, (__pyx_v_src_strides + 1), __pyx_v_dst_data, (__pyx_v_dst_strides + 1), (__pyx_v_src_shape + 1), (__pyx_v_dst_shape + 1), (__pyx_v_ndim - 1), __pyx_v_itemsize);

      /* "View.MemoryView":1167
 *                                      src_shape + 1, dst_shape + 1,
 *                                      ndim - 1, itemsize)
 *             src_data += src_stride             # <<<<<<<<<<<<<<
 *             dst_data += dst_stride
 * 
 */
      __pyx_v_src_data = (__pyx_v_src_data + __pyx_v_src_stride);

      /* "View.MemoryView":1168
 *                                      ndim - 1, itemsize)
 *             src_data += src_stride
 *             dst_data += dst_stride             # <<<<<<<<<<<<<<
 * 
 * cdef void copy_strided_to_strided(__Pyx_memviewslice *src,
 */
      __pyx_v_dst_data = (__pyx_v_dst_data + __pyx_v_dst_stride);
    }
  }
  __pyx_L3:;

  /* "View.MemoryView":1140
 * 
 * @cython.cdivision(True)
 * cdef void _copy_strided_to_strided(char *src_data, Py_ssize_t *src_strides,             # <<<<<<<<<<<<<<
 *                                    char *dst_data, Py_ssize_t *dst_strides,
 *                                    Py_ssize_t *src_shape, Py_ssize_t *dst_shape,
 */

  /* function exit code */
}

/* "View.MemoryView":1170
 *             dst_data += dst_stride
 * 
 * cdef void copy_strided_to_strided(__Pyx_memviewslice *src,             # <<<<<<<<<<<<<<
 *                                   __Pyx_memviewslice *dst,
 *                                   int ndim, size_t itemsize) nogil:
 */

static void copy_strided_to_strided(__Pyx_memviewslice *__pyx_v_src, __Pyx_memviewslice *__pyx_v_dst, int __pyx_v_ndim, size_t __pyx_v_itemsize) {

  /* "View.MemoryView":1173
 *                                   __Pyx_memviewslice *dst,
 *                                   int ndim, size_t itemsize) nogil:
 *     _copy_strided_to_strided(src.data, src.strides, dst.data, dst.strides,             # <<<<<<<<<<<<<<
 *                              src.shape, dst.shape, ndim, itemsize)
 * 
 */
  _copy_strided_to_strided(__pyx_v_src->data, __pyx_v_src->strides, __pyx_v_dst->data, __pyx_v_dst->strides, __pyx_v_src->shape, __pyx_v_dst->shape, __pyx_v_ndim, __pyx_v_itemsize);

  /* "View.MemoryView":1170
 *             dst_data += dst_stride
 * 
 * cdef void copy_strided_to_strided(__Pyx_memviewslice *src,             # <<<<<<<<<<<<<<
 *                                   __Pyx_memviewslice *dst,
 *                                   int ndim, size_t itemsize) nogil:
 */

  /* function exit code */
}

/* "View.MemoryView":1177
 * 
 * @cname('__pyx_memoryview_slice_get_size')
 * cdef Py_ssize_t slice_get_size(__Pyx_memviewslice *src, int ndim) nogil:             # <<<<<<<<<<<<<<
 *     "Return the size of the memory occupied by the slice in number of bytes"
 *     cdef int i
 */

static Py_ssize_t __pyx_memoryview_slice_get_size(__Pyx_memviewslice *__pyx_v_src, int __pyx_v_ndim) {
  int __pyx_v_i;
  Py_ssize_t __pyx_v_size;
  Py_ssize_t __pyx_r;
  Py_ssize_t __pyx_t_1;
  int __pyx_t_2;
  int __pyx_t_3;
  int __pyx_t_4;

  /* "View.MemoryView":1180
 *     "Return the size of the memory occupied by the slice in number of bytes"
 *     cdef int i
 *     cdef Py_ssize_t size = src.memview.view.itemsize             # <<<<<<<<<<<<<<
 * 
 *     for i in range(ndim):
 */
  __pyx_t_1 = __pyx_v_src->memview->view.itemsize;
  __pyx_v_size = __pyx_t_1;

  /* "View.MemoryView":1182
 *     cdef Py_ssize_t size = src.memview.view.itemsize
 * 
 *     for i in range(ndim):             # <<<<<<<<<<<<<<
 *         size *= src.shape[i]
 * 
 */
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  __pyx_t_3 = __pyx_t_2;
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    __pyx_v_i = __pyx_t_4;

    /* "View.MemoryView":1183
 * 
 *     for i in range(ndim):
 *         size *= src.shape[i]             # <<<<<<<<<<<<<<
 * 
 *     return size
 */
    __pyx_v_size = (__pyx_v_size * (__pyx_v_src->shape[__pyx_v_i]));
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  /* "View.MemoryView":1185
 *         size *= src.shape[i]
 * 
 *     return size             # <<<<<<<<<<<<<<
 * 
 * @cname('__pyx_fill_contig_strides_array')
 */
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  /* "View.MemoryView":1177
 * 
 * @cname('__pyx_memoryview_slice_get_size')
 * cdef Py_ssize_t slice_get_size(__Pyx_memviewslice *src, int ndim) nogil:             # <<<<<<<<<<<<<<
 *     "Return the size of the memory occupied by the slice in number of bytes"
 *     cdef int i
 */

  /* function exit code */
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}

/* "View.MemoryView":1188
 * 
 * @cname('__pyx_fill_contig_strides_array')
 * cdef Py_ssize_t fill_contig_strides_array(             # <<<<<<<<<<<<<<
 *                 Py_ssize_t *shape, Py_ssize_t *strides, Py_ssize_t stride,
 *                 int ndim, char order) nogil:
 */

static Py_ssize_t __pyx_fill_contig_strides_array(Py_ssize_t *__pyx_v_shape, Py_ssize_t *__pyx_v_strides, Py_ssize_t __pyx_v_stride, int __pyx_v_ndim, char __pyx_v_order) {
  int __pyx_v_idx;
  Py_ssize_t __pyx_r;
  int __pyx_t_1;
  int __pyx_t_2;
  int __pyx_t_3;
  int __pyx_t_4;

  /* "View.MemoryView":1197
 *     cdef int idx
 * 
 *     if order == 'F':             # <<<<<<<<<<<<<<
 *         for idx in range(ndim):
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 */
  __pyx_t_1 = ((__pyx_v_order == 'F') != 0);
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    /* "View.MemoryView":1198
 * 
 *     if order == 'F':
 *         for idx in range(ndim):             # <<<<<<<<<<<<<<
 *             strides[idx] = stride
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 */
    __pyx_t_2 = __pyx_v_ndim;
    __pyx_t_3 = __pyx_t_2;
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      __pyx_v_idx = __pyx_t_4;

      /* "View.MemoryView":1199
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 *             strides[idx] = stride             # <<<<<<<<<<<<<<
 *             stride = stride * shape[idx]
 *     else:
 */
      (__pyx_v_strides[__pyx_v_idx]) = __pyx_v_stride;

      /* "View.MemoryView":1200
 *         for idx in range(ndim):
 *             strides[idx] = stride
 *             stride = stride * shape[idx]             # <<<<<<<<<<<<<<
 *     else:
 *         for idx in range(ndim - 1, -1, -1):
 */
      __pyx_v_stride = (__pyx_v_stride * (__pyx_v_shape[__pyx_v_idx]));
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    /* "View.MemoryView":1197
 *     cdef int idx
 * 
 *     if order == 'F':             # <<<<<<<<<<<<<<
 *         for idx in range(ndim):
 *             strides[idx] = stride
 */
    goto __pyx_L3;
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  /* "View.MemoryView":1202
 *             stride = stride * shape[idx]
 *     else:
 *         for idx in range(ndim - 1, -1, -1):             # <<<<<<<<<<<<<<
 *             strides[idx] = stride
 *             stride = stride * shape[idx]
 */
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    for (__pyx_t_2 = (__pyx_v_ndim - 1); __pyx_t_2 > -1; __pyx_t_2-=1) {
      __pyx_v_idx = __pyx_t_2;

      /* "View.MemoryView":1203
 *     else:
 *         for idx in range(ndim - 1, -1, -1):
 *             strides[idx] = stride             # <<<<<<<<<<<<<<
 *             stride = stride * shape[idx]
 * 
 */
      (__pyx_v_strides[__pyx_v_idx]) = __pyx_v_stride;

      /* "View.MemoryView":1204
 *         for idx in range(ndim - 1, -1, -1):
 *             strides[idx] = stride
 *             stride = stride * shape[idx]             # <<<<<<<<<<<<<<
 * 
 *     return stride
 */
      __pyx_v_stride = (__pyx_v_stride * (__pyx_v_shape[__pyx_v_idx]));
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  /* "View.MemoryView":1206
 *             stride = stride * shape[idx]
 * 
 *     return stride             # <<<<<<<<<<<<<<
 * 
 * @cname('__pyx_memoryview_copy_data_to_temp')
 */
  __pyx_r = __pyx_v_stride;
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  /* "View.MemoryView":1188
 * 
 * @cname('__pyx_fill_contig_strides_array')
 * cdef Py_ssize_t fill_contig_strides_array(             # <<<<<<<<<<<<<<
 *                 Py_ssize_t *shape, Py_ssize_t *strides, Py_ssize_t stride,
 *                 int ndim, char order) nogil:
 */

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}

/* "View.MemoryView":1209
 * 
 * @cname('__pyx_memoryview_copy_data_to_temp')
 * cdef void *copy_data_to_temp(__Pyx_memviewslice *src,             # <<<<<<<<<<<<<<
 *                              __Pyx_memviewslice *tmpslice,
 *                              char order,
 */

static void *__pyx_memoryview_copy_data_to_temp(__Pyx_memviewslice *__pyx_v_src, __Pyx_memviewslice *__pyx_v_tmpslice, char __pyx_v_order, int __pyx_v_ndim) {
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  int __pyx_t_5;
  int __pyx_t_6;

  /* "View.MemoryView":1220
 *     cdef void *result
 * 
 *     cdef size_t itemsize = src.memview.view.itemsize             # <<<<<<<<<<<<<<
 *     cdef size_t size = slice_get_size(src, ndim)
 * 
 */
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  /* "View.MemoryView":1221
 * 
 *     cdef size_t itemsize = src.memview.view.itemsize
 *     cdef size_t size = slice_get_size(src, ndim)             # <<<<<<<<<<<<<<
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 */
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  /* "View.MemoryView":1223
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 * 
 *     result = malloc(size)             # <<<<<<<<<<<<<<
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 */
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  /* "View.MemoryView":1224
 * 
 *     result = malloc(size)
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 */
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    /* "View.MemoryView":1225
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 * 
 */
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    /* "View.MemoryView":1224
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 *     result = malloc(size)
 *     if not result:             # <<<<<<<<<<<<<<
 *         _err(MemoryError, NULL)
 * 
 */
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 * 
 * 
 *     tmpslice.data = <char *> result             # <<<<<<<<<<<<<<
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 */
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  /* "View.MemoryView":1229
 * 
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 */
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  /* "View.MemoryView":1230
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 *     for i in range(ndim):             # <<<<<<<<<<<<<<
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 */
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    /* "View.MemoryView":1231
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 *     for i in range(ndim):
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 * 
 */
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    /* "View.MemoryView":1232
 *     for i in range(ndim):
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 *         tmpslice.suboffsets[i] = -1             # <<<<<<<<<<<<<<
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 *     fill_contig_strides_array(&tmpslice.shape[0], &tmpslice.strides[0], itemsize,
 */
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 * 
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 */
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  /* "View.MemoryView":1238
 * 
 * 
 *     for i in range(ndim):             # <<<<<<<<<<<<<<
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    /* "View.MemoryView":1239
 * 
 *     for i in range(ndim):
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 *             tmpslice.strides[i] = 0
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 */
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 * 
 *     if slice_is_contig(src[0], order, ndim):
 */
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 * 
 *     for i in range(ndim):
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 */
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    /* "View.MemoryView":1243
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 *     if slice_is_contig(src[0], order, ndim):
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 */
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 * 
 *     if slice_is_contig(src[0], order, ndim):             # <<<<<<<<<<<<<<
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 */
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 * 
 */
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 */
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 *             _err_dim(ValueError, "Dimension %d is not direct", i)
 * 
 *     if slices_overlap(&src, &dst, ndim, itemsize):             # <<<<<<<<<<<<<<
 * 
 *         if not slice_is_contig(src, order, ndim):
 */
  }

  /* "View.MemoryView":1311
 *         src = tmp
 * 
 *     if not broadcasting:             # <<<<<<<<<<<<<<
 * 
 * 
 */
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    /* "View.MemoryView":1314
 * 
 * 
 *         if slice_is_contig(src, 'C', ndim):             # <<<<<<<<<<<<<<
 *             direct_copy = slice_is_contig(dst, 'C', ndim)
 *         elif slice_is_contig(src, 'F', ndim):
 */
    __pyx_t_2 = (__pyx_memviewslice_is_contig(__pyx_v_src, 'C', __pyx_v_ndim) != 0);
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      /* "View.MemoryView":1315
 * 
 *         if slice_is_contig(src, 'C', ndim):
 *             direct_copy = slice_is_contig(dst, 'C', ndim)             # <<<<<<<<<<<<<<
 *         elif slice_is_contig(src, 'F', ndim):
 *             direct_copy = slice_is_contig(dst, 'F', ndim)
 */
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      /* "View.MemoryView":1314
 * 
 * 
 *         if slice_is_contig(src, 'C', ndim):             # <<<<<<<<<<<<<<
 *             direct_copy = slice_is_contig(dst, 'C', ndim)
 *         elif slice_is_contig(src, 'F', ndim):
 */
      goto __pyx_L12;
    }

    /* "View.MemoryView":1316
 *         if slice_is_contig(src, 'C', ndim):
 *             direct_copy = slice_is_contig(dst, 'C', ndim)
 *         elif slice_is_contig(src, 'F', ndim):             # <<<<<<<<<<<<<<
 *             direct_copy = slice_is_contig(dst, 'F', ndim)
 * 
 */
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      /* "View.MemoryView":1317
 *             direct_copy = slice_is_contig(dst, 'C', ndim)
 *         elif slice_is_contig(src, 'F', ndim):
 *             direct_copy = slice_is_contig(dst, 'F', ndim)             # <<<<<<<<<<<<<<
 * 
 *         if direct_copy:
 */
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      /* "View.MemoryView":1316
 *         if slice_is_contig(src, 'C', ndim):
 *             direct_copy = slice_is_contig(dst, 'C', ndim)
 *         elif slice_is_contig(src, 'F', ndim):             # <<<<<<<<<<<<<<
 *             direct_copy = slice_is_contig(dst, 'F', ndim)
 * 
 */
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    /* "View.MemoryView":1319
 *             direct_copy = slice_is_contig(dst, 'F', ndim)
 * 
 *         if direct_copy:             # <<<<<<<<<<<<<<
 * 
 *             refcount_copying(&dst, dtype_is_object, ndim, False)
 */
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      /* "View.MemoryView":1321
 *         if direct_copy:
 * 
 *             refcount_copying(&dst, dtype_is_object, ndim, False)             # <<<<<<<<<<<<<<
 *             memcpy(dst.data, src.data, slice_get_size(&src, ndim))
 *             refcount_copying(&dst, dtype_is_object, ndim, True)
 */
      __pyx_memoryview_refcount_copying((&__pyx_v_dst), __pyx_v_dtype_is_object, __pyx_v_ndim, 0);

      /* "View.MemoryView":1322
 * 
 *             refcount_copying(&dst, dtype_is_object, ndim, False)
 *             memcpy(dst.data, src.data, slice_get_size(&src, ndim))             # <<<<<<<<<<<<<<
 *             refcount_copying(&dst, dtype_is_object, ndim, True)
 *             free(tmpdata)
 */
      (void)(memcpy(__pyx_v_dst.data, __pyx_v_src.data, __pyx_memoryview_slice_get_size((&__pyx_v_src), __pyx_v_ndim)));

      /* "View.MemoryView":1323
 *             refcount_copying(&dst, dtype_is_object, ndim, False)
 *             memcpy(dst.data, src.data, slice_get_size(&src, ndim))
 *             refcount_copying(&dst, dtype_is_object, ndim, True)             # <<<<<<<<<<<<<<
 *             free(tmpdata)
 *             return 0
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      /* "View.MemoryView":1324
 *             memcpy(dst.data, src.data, slice_get_size(&src, ndim))
 *             refcount_copying(&dst, dtype_is_object, ndim, True)
 *             free(tmpdata)             # <<<<<<<<<<<<<<
 *             return 0
 * 
 */
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 *             refcount_copying(&dst, dtype_is_object, ndim, True)
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 *     if order == 'F' == get_best_order(&dst, ndim):
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 *             direct_copy = slice_is_contig(dst, 'F', ndim)
 * 
 *         if direct_copy:             # <<<<<<<<<<<<<<
 * 
 *             refcount_copying(&dst, dtype_is_object, ndim, False)
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    /* "View.MemoryView":1311
 *         src = tmp
 * 
 *     if not broadcasting:             # <<<<<<<<<<<<<<
 * 
 * 
 */
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 * 
 *     if order == 'F' == get_best_order(&dst, ndim):             # <<<<<<<<<<<<<<
 * 
 * 
 */
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 * 
 * 
 *         transpose_memslice(&src)             # <<<<<<<<<<<<<<
 *         transpose_memslice(&dst)
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 */
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 * 
 *         transpose_memslice(&src)
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 * 
 *     refcount_copying(&dst, dtype_is_object, ndim, False)
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 * 
 *     if order == 'F' == get_best_order(&dst, ndim):             # <<<<<<<<<<<<<<
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 * 
 */
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 * 
 *     refcount_copying(&dst, dtype_is_object, ndim, False)             # <<<<<<<<<<<<<<
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 * 
 *     refcount_copying(&dst, dtype_is_object, ndim, False)
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 *     refcount_copying(&dst, dtype_is_object, ndim, True)
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 */
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 * 
 *     free(tmpdata)
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 * 
 *     free(tmpdata)             # <<<<<<<<<<<<<<
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 *     free(tmpdata)
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 *     for i in range(ndim - 1, -1, -1):             # <<<<<<<<<<<<<<
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 * 
 *     for i in range(ndim - 1, -1, -1):
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 * 
 *     for i in range(offset):             # <<<<<<<<<<<<<<
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 * 
 *     for i in range(offset):
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 *     for i in range(offset):
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 * 
 */
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/* "View.MemoryView":1363
 * 
 * @cname('__pyx_memoryview_refcount_copying')
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 * 
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/* "View.MemoryView":1372
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/* "View.MemoryView":1398
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  return __pyx_pw_15View_dot_MemoryView_10memoryview_5shape_1__get__(o);
}

static PyObject *__pyx_getprop___pyx_memoryview_strides(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_15View_dot_MemoryView_10memoryview_7strides_1__get__(o);
}

static PyObject *__pyx_getprop___pyx_memoryview_suboffsets(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_15View_dot_MemoryView_10memoryview_10suboffsets_1__get__(o);
}

static PyObject *__pyx_getprop___pyx_memoryview_ndim(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_15View_dot_MemoryView_10memoryview_4ndim_1__get__(o);
}

static PyObject *__pyx_getprop___pyx_memoryview_itemsize(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_15View_dot_MemoryView_10memoryview_8itemsize_1__get__(o);
}

static PyObject *__pyx_getprop___pyx_memoryview_nbytes(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_15View_dot_MemoryView_10memoryview_6nbytes_1__get__(o);
}

static PyObject *__pyx_getprop___pyx_memoryview_size(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_15View_dot_MemoryView_10memoryview_4size_1__get__(o);
}

static PyMethodDef __pyx_methods_memoryview[] = {
  {"is_c_contig", (PyCFunction)__pyx_memoryview_is_c_contig, METH_NOARGS, 0},
  {"is_f_contig", (PyCFunction)__pyx_memoryview_is_f_contig, METH_NOARGS, 0},
  {"copy", (PyCFunction)__pyx_memoryview_copy, METH_NOARGS, 0},
  {"copy_fortran", (PyCFunction)__pyx_memoryview_copy_fortran, METH_NOARGS, 0},
  {"__reduce_cython__", (PyCFunction)__pyx_pw___pyx_memoryview_1__reduce_cython__, METH_NOARGS, 0},
  {"__setstate_cython__", (PyCFunction)__pyx_pw___pyx_memoryview_3__setstate_cython__, METH_O, 0},
  {0, 0, 0, 0}
};

static struct PyGetSetDef __pyx_getsets_memoryview[] = {
  {(char *)"T", __pyx_getprop___pyx_memoryview_T, 0, (char *)0, 0},
  {(char *)"base", __pyx_getprop___pyx_memoryview_base, 0, (char *)0, 0},
  {(char *)"shape", __pyx_getprop___pyx_memoryview_shape, 0, (char *)0, 0},
  {(char *)"strides", __pyx_getprop___pyx_memoryview_strides, 0, (char *)0, 0},
  {(char *)"suboffsets", __pyx_getprop___pyx_memoryview_suboffsets, 0, (char *)0, 0},
  {(char *)"ndim", __pyx_getprop___pyx_memoryview_ndim, 0, (char *)0, 0},
  {(char *)"itemsize", __pyx_getprop___pyx_memoryview_itemsize, 0, (char *)0, 0},
  {(char *)"nbytes", __pyx_getprop___pyx_memoryview_nbytes, 0, (char *)0, 0},
  {(char *)"size", __pyx_getprop___pyx_memoryview_size, 0, (char *)0, 0},
  {0, 0, 0, 0, 0}
};

static PySequenceMethods __pyx_tp_as_sequence_memoryview = {
  __pyx_memoryview___len__, /*sq_length*/
  0, /*sq_concat*/
  0, /*sq_repeat*/
  __pyx_sq_item_memoryview, /*sq_item*/
  0, /*sq_slice*/
  0, /*sq_ass_item*/
  0, /*sq_ass_slice*/
  0, /*sq_contains*/
  0, /*sq_inplace_concat*/
  0, /*sq_inplace_repeat*/
};

static PyMappingMethods __pyx_tp_as_mapping_memoryview = {
  __pyx_memoryview___len__, /*mp_length*/
  __pyx_memoryview___getitem__, /*mp_subscript*/
  __pyx_mp_ass_subscript_memoryview, /*mp_ass_subscript*/
};

static PyBufferProcs __pyx_tp_as_buffer_memoryview = {
  #if PY_MAJOR_VERSION < 3
  0, /*bf_getreadbuffer*/
  #endif
  #if PY_MAJOR_VERSION < 3
  0, /*bf_getwritebuffer*/
  #endif
  #if PY_MAJOR_VERSION < 3
  0, /*bf_getsegcount*/
  #endif
  #if PY_MAJOR_VERSION < 3
  0, /*bf_getcharbuffer*/
  #endif
  __pyx_memoryview_getbuffer, /*bf_getbuffer*/
  0, /*bf_releasebuffer*/
};

static PyTypeObject __pyx_type___pyx_memoryview = {
  PyVarObject_HEAD_INIT(0, 0)
  "CRADLE.CorrectBias.calculateOnebp.memoryview", /*tp_name*/
  sizeof(struct __pyx_memoryview_obj), /*tp_basicsize*/
  0, /*tp_itemsize*/
  __pyx_tp_dealloc_memoryview, /*tp_dealloc*/
  0, /*tp_print*/
  0, /*tp_getattr*/
  0, /*tp_setattr*/
  #if PY_MAJOR_VERSION < 3
  0, /*tp_compare*/
  #endif
  #if PY_MAJOR_VERSION >= 3
  0, /*tp_as_async*/
  #endif
  __pyx_memoryview___repr__, /*tp_repr*/
  0, /*tp_as_number*/
  &__pyx_tp_as_sequence_memoryview, /*tp_as_sequence*/
  &__pyx_tp_as_mapping_memoryview, /*tp_as_mapping*/
  0, /*tp_hash*/
  0, /*tp_call*/
  __pyx_memoryview___str__, /*tp_str*/
  0, /*tp_getattro*/
  0, /*tp_setattro*/
  &__pyx_tp_as_buffer_memoryview, /*tp_as_buffer*/
  Py_TPFLAGS_DEFAULT|Py_TPFLAGS_HAVE_VERSION_TAG|Py_TPFLAGS_CHECKTYPES|Py_TPFLAGS_HAVE_NEWBUFFER|Py_TPFLAGS_BASETYPE|Py_TPFLAGS_HAVE_GC, /*tp_flags*/
  0, /*tp_doc*/
  __pyx_tp_traverse_memoryview, /*tp_traverse*/
  __pyx_tp_clear_memoryview, /*tp_clear*/
  0, /*tp_richcompare*/
  0, /*tp_weaklistoffset*/
  0, /*tp_iter*/
  0, /*tp_iternext*/
  __pyx_methods_memoryview, /*tp_methods*/
  0, /*tp_members*/
  __pyx_getsets_memoryview, /*tp_getset*/
  0, /*tp_base*/
  0, /*tp_dict*/
  0, /*tp_descr_get*/
  0, /*tp_descr_set*/
  0, /*tp_dictoffset*/
  0, /*tp_init*/
  0, /*tp_alloc*/
  __pyx_tp_new_memoryview, /*tp_new*/
  0, /*tp_free*/
  0, /*tp_is_gc*/
  0, /*tp_bases*/
  0, /*tp_mro*/
  0, /*tp_cache*/
  0, /*tp_subclasses*/
  0, /*tp_weaklist*/
  0, /*tp_del*/
  0, /*tp_version_tag*/
  #if PY_VERSION_HEX >= 0x030400a1
  0, /*tp_finalize*/
  #endif
  #if PY_VERSION_HEX >= 0x030800b1
  0, /*tp_vectorcall*/
  #endif
};
static struct __pyx_vtabstruct__memoryviewslice __pyx_vtable__memoryviewslice;

static PyObject *__pyx_tp_new__memoryviewslice(PyTypeObject *t, PyObject *a, PyObject *k) {
  struct __pyx_memoryviewslice_obj *p;
  PyObject *o = __pyx_tp_new_memoryview(t, a, k);
  if (unlikely(!o)) return 0;
  p = ((struct __pyx_memoryviewslice_obj *)o);
  p->__pyx_base.__pyx_vtab = (struct __pyx_vtabstruct_memoryview*)__pyx_vtabptr__memoryviewslice;
  p->from_object = Py_None; Py_INCREF(Py_None);
  p->from_slice.memview = NULL;
  return o;
}

static void __pyx_tp_dealloc__memoryviewslice(PyObject *o) {
  struct __pyx_memoryviewslice_obj *p = (struct __pyx_memoryviewslice_obj *)o;
  #if CYTHON_USE_TP_FINALIZE
  if (unlikely(PyType_HasFeature(Py_TYPE(o), Py_TPFLAGS_HAVE_FINALIZE) && Py_TYPE(o)->tp_finalize) && !_PyGC_FINALIZED(o)) {
    if (PyObject_CallFinalizerFromDealloc(o)) return;
  }
  #endif
  PyObject_GC_UnTrack(o);
  {
    PyObject *etype, *eval, *etb;
    PyErr_Fetch(&etype, &eval, &etb);
    ++Py_REFCNT(o);
    __pyx_memoryviewslice___dealloc__(o);
    --Py_REFCNT(o);
    PyErr_Restore(etype, eval, etb);
  }
  Py_CLEAR(p->from_object);
  PyObject_GC_Track(o);
  __pyx_tp_dealloc_memoryview(o);
}

static int __pyx_tp_traverse__memoryviewslice(PyObject *o, visitproc v, void *a) {
  int e;
  struct __pyx_memoryviewslice_obj *p = (struct __pyx_memoryviewslice_obj *)o;
  e = __pyx_tp_traverse_memoryview(o, v, a); if (e) return e;
  if (p->from_object) {
    e = (*v)(p->from_object, a); if (e) return e;
  }
  return 0;
}

static int __pyx_tp_clear__memoryviewslice(PyObject *o) {
  PyObject* tmp;
  struct __pyx_memoryviewslice_obj *p = (struct __pyx_memoryviewslice_obj *)o;
  __pyx_tp_clear_memoryview(o);
  tmp = ((PyObject*)p->from_object);
  p->from_object = Py_None; Py_INCREF(Py_None);
  Py_XDECREF(tmp);
  __PYX_XDEC_MEMVIEW(&p->from_slice, 1);
  return 0;
}

static PyObject *__pyx_getprop___pyx_memoryviewslice_base(PyObject *o, CYTHON_UNUSED void *x) {
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}

static PyMethodDef __pyx_methods__memoryviewslice[] = {
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  {"__setstate_cython__", (PyCFunction)__pyx_pw___pyx_memoryviewslice_3__setstate_cython__, METH_O, 0},
  {0, 0, 0, 0}
};

static struct PyGetSetDef __pyx_getsets__memoryviewslice[] = {
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  {0, 0, 0, 0, 0}
};

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  0, /*tp_itemsize*/
  __pyx_tp_dealloc__memoryviewslice, /*tp_dealloc*/
  0, /*tp_print*/
  0, /*tp_getattr*/
  0, /*tp_setattr*/
  #if PY_MAJOR_VERSION < 3
  0, /*tp_compare*/
  #endif
  #if PY_MAJOR_VERSION >= 3
  0, /*tp_as_async*/
  #endif
  #if CYTHON_COMPILING_IN_PYPY
  __pyx_memoryview___repr__, /*tp_repr*/
  #else
  0, /*tp_repr*/
  #endif
  0, /*tp_as_number*/
  0, /*tp_as_sequence*/
  0, /*tp_as_mapping*/
  0, /*tp_hash*/
  0, /*tp_call*/
  #if CYTHON_COMPILING_IN_PYPY
  __pyx_memoryview___str__, /*tp_str*/
  #else
  0, /*tp_str*/
  #endif
  0, /*tp_getattro*/
  0, /*tp_setattro*/
  0, /*tp_as_buffer*/
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  "Internal class for passing memoryview slices to Python", /*tp_doc*/
  __pyx_tp_traverse__memoryviewslice, /*tp_traverse*/
  __pyx_tp_clear__memoryviewslice, /*tp_clear*/
  0, /*tp_richcompare*/
  0, /*tp_weaklistoffset*/
  0, /*tp_iter*/
  0, /*tp_iternext*/
  __pyx_methods__memoryviewslice, /*tp_methods*/
  0, /*tp_members*/
  __pyx_getsets__memoryviewslice, /*tp_getset*/
  0, /*tp_base*/
  0, /*tp_dict*/
  0, /*tp_descr_get*/
  0, /*tp_descr_set*/
  0, /*tp_dictoffset*/
  0, /*tp_init*/
  0, /*tp_alloc*/
  __pyx_tp_new__memoryviewslice, /*tp_new*/
  0, /*tp_free*/
  0, /*tp_is_gc*/
  0, /*tp_bases*/
  0, /*tp_mro*/
  0, /*tp_cache*/
  0, /*tp_subclasses*/
  0, /*tp_weaklist*/
  0, /*tp_del*/
  0, /*tp_version_tag*/
  #if PY_VERSION_HEX >= 0x030400a1
  0, /*tp_finalize*/
  #endif
  #if PY_VERSION_HEX >= 0x030800b1
  0, /*tp_vectorcall*/
  #endif
};

static PyMethodDef __pyx_methods[] = {
  {"calculateContinuousFrag", (PyCFunction)(void*)(PyCFunctionWithKeywords)__pyx_pw_6CRADLE_11CorrectBias_14calculateOnebp_1calculateContinuousFrag, METH_VARARGS|METH_KEYWORDS, 0},
  {"calculateDiscreteFrag", (PyCFunction)(void*)(PyCFunctionWithKeywords)__pyx_pw_6CRADLE_11CorrectBias_14calculateOnebp_3calculateDiscreteFrag, METH_VARARGS|METH_KEYWORDS, 0},
  {"calculateTrainCovariates", (PyCFunction)__pyx_pw_6CRADLE_11CorrectBias_14calculateOnebp_5calculateTrainCovariates, METH_O, 0},
  {"calculateTaskCovariates", (PyCFunction)__pyx_pw_6CRADLE_11CorrectBias_14calculateOnebp_7calculateTaskCovariates, METH_O, 0},
  {"performRegression", (PyCFunction)__pyx_pw_6CRADLE_11CorrectBias_14calculateOnebp_9performRegression, METH_O, 0},
  {"memoryView", (PyCFunction)__pyx_pw_6CRADLE_11CorrectBias_14calculateOnebp_11memoryView, METH_O, 0},
  {"makeMatrixContinuousFragTrain", (PyCFunction)(void*)(PyCFunctionWithKeywords)__pyx_pw_6CRADLE_11CorrectBias_14calculateOnebp_13makeMatrixContinuousFragTrain, METH_VARARGS|METH_KEYWORDS, 0},
  {"makeMatrixContinuousFrag", (PyCFunction)(void*)(PyCFunctionWithKeywords)__pyx_pw_6CRADLE_11CorrectBias_14calculateOnebp_15makeMatrixContinuousFrag, METH_VARARGS|METH_KEYWORDS, 0},
  {"makeMatrixDiscreteFrag", (PyCFunction)(void*)(PyCFunctionWithKeywords)__pyx_pw_6CRADLE_11CorrectBias_14calculateOnebp_17makeMatrixDiscreteFrag, METH_VARARGS|METH_KEYWORDS, 0},
  {"find5merProb", (PyCFunction)__pyx_pw_6CRADLE_11CorrectBias_14calculateOnebp_19find5merProb, METH_O, 0},
  {"edit5merProb", (PyCFunction)(void*)(PyCFunctionWithKeywords)__pyx_pw_6CRADLE_11CorrectBias_14calculateOnebp_21edit5merProb, METH_VARARGS|METH_KEYWORDS, 0},
  {"findComple5merProb", (PyCFunction)__pyx_pw_6CRADLE_11CorrectBias_14calculateOnebp_23findComple5merProb, METH_O, 0},
  {"editComple5merProb", (PyCFunction)(void*)(PyCFunctionWithKeywords)__pyx_pw_6CRADLE_11CorrectBias_14calculateOnebp_25editComple5merProb, METH_VARARGS|METH_KEYWORDS, 0},
  {"findStartGibbs", (PyCFunction)(void*)(PyCFunctionWithKeywords)__pyx_pw_6CRADLE_11CorrectBias_14calculateOnebp_27findStartGibbs, METH_VARARGS|METH_KEYWORDS, 0},
  {"editStartGibbs", (PyCFunction)(void*)(PyCFunctionWithKeywords)__pyx_pw_6CRADLE_11CorrectBias_14calculateOnebp_29editStartGibbs, METH_VARARGS|METH_KEYWORDS, 0},
  {"convertGibbs", (PyCFunction)__pyx_pw_6CRADLE_11CorrectBias_14calculateOnebp_31convertGibbs, METH_O, 0},
  {"correctReadCount", (PyCFunction)(void*)(PyCFunctionWithKeywords)__pyx_pw_6CRADLE_11CorrectBias_14calculateOnebp_33correctReadCount, METH_VARARGS|METH_KEYWORDS, 0},
  {"selectIdx", (PyCFunction)(void*)(PyCFunctionWithKeywords)__pyx_pw_6CRADLE_11CorrectBias_14calculateOnebp_35selectIdx, METH_VARARGS|METH_KEYWORDS, 0},
  {"writeBedFile", (PyCFunction)(void*)(PyCFunctionWithKeywords)__pyx_pw_6CRADLE_11CorrectBias_14calculateOnebp_37writeBedFile, METH_VARARGS|METH_KEYWORDS, 0},
  {0, 0, 0, 0}
};

#if PY_MAJOR_VERSION >= 3
#if CYTHON_PEP489_MULTI_PHASE_INIT
static PyObject* __pyx_pymod_create(PyObject *spec, PyModuleDef *def); /*proto*/
static int __pyx_pymod_exec_calculateOnebp(PyObject* module); /*proto*/
static PyModuleDef_Slot __pyx_moduledef_slots[] = {
  {Py_mod_create, (void*)__pyx_pymod_create},
  {Py_mod_exec, (void*)__pyx_pymod_exec_calculateOnebp},
  {0, NULL}
};
#endif

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  #if CYTHON_PEP489_MULTI_PHASE_INIT
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  #else
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  #if CYTHON_PEP489_MULTI_PHASE_INIT
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    NULL, /* m_reload */
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    NULL, /* m_traverse */
    NULL, /* m_clear */
    NULL /* m_free */
};
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#if defined(__clang__)
    #define CYTHON_SMALL_CODE
#elif defined(__GNUC__) && (__GNUC__ > 4 || (__GNUC__ == 4 && __GNUC_MINOR__ >= 3))
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    #define CYTHON_SMALL_CODE
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#ifdef HAVE_LONG_LONG
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#ifdef HAVE_LONG_LONG
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#ifdef HAVE_LONG_LONG
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#ifdef HAVE_LONG_LONG
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#endif
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#endif
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#if CYTHON_FAST_PYCALL
static PyObject* __Pyx_PyFunction_FastCallNoKw(PyCodeObject *co, PyObject **args, Py_ssize_t na,
                                               PyObject *globals) {
    PyFrameObject *f;
    PyThreadState *tstate = __Pyx_PyThreadState_Current;
    PyObject **fastlocals;
    Py_ssize_t i;
    PyObject *result;
    assert(globals != NULL);
    /* XXX Perhaps we should create a specialized
       PyFrame_New() that doesn't take locals, but does
       take builtins without sanity checking them.
       */
    assert(tstate != NULL);
    f = PyFrame_New(tstate, co, globals, NULL);
    if (f == NULL) {
        return NULL;
    }
    fastlocals = __Pyx_PyFrame_GetLocalsplus(f);
    for (i = 0; i < na; i++) {
        Py_INCREF(*args);
        fastlocals[i] = *args++;
    }
    result = PyEval_EvalFrameEx(f,0);
    ++tstate->recursion_depth;
    Py_DECREF(f);
    --tstate->recursion_depth;
    return result;
}
#if 1 || PY_VERSION_HEX < 0x030600B1
static PyObject *__Pyx_PyFunction_FastCallDict(PyObject *func, PyObject **args, Py_ssize_t nargs, PyObject *kwargs) {
    PyCodeObject *co = (PyCodeObject *)PyFunction_GET_CODE(func);
    PyObject *globals = PyFunction_GET_GLOBALS(func);
    PyObject *argdefs = PyFunction_GET_DEFAULTS(func);
    PyObject *closure;
#if PY_MAJOR_VERSION >= 3
    PyObject *kwdefs;
#endif
    PyObject *kwtuple, **k;
    PyObject **d;
    Py_ssize_t nd;
    Py_ssize_t nk;
    PyObject *result;
    assert(kwargs == NULL || PyDict_Check(kwargs));
    nk = kwargs ? PyDict_Size(kwargs) : 0;
    if (Py_EnterRecursiveCall((char*)" while calling a Python object")) {
        return NULL;
    }
    if (
#if PY_MAJOR_VERSION >= 3
            co->co_kwonlyargcount == 0 &&
#endif
            likely(kwargs == NULL || nk == 0) &&
            co->co_flags == (CO_OPTIMIZED | CO_NEWLOCALS | CO_NOFREE)) {
        if (argdefs == NULL && co->co_argcount == nargs) {
            result = __Pyx_PyFunction_FastCallNoKw(co, args, nargs, globals);
            goto done;
        }
        else if (nargs == 0 && argdefs != NULL
                 && co->co_argcount == Py_SIZE(argdefs)) {
            /* function called with no arguments, but all parameters have
               a default value: use default values as arguments .*/
            args = &PyTuple_GET_ITEM(argdefs, 0);
            result =__Pyx_PyFunction_FastCallNoKw(co, args, Py_SIZE(argdefs), globals);
            goto done;
        }
    }
    if (kwargs != NULL) {
        Py_ssize_t pos, i;
        kwtuple = PyTuple_New(2 * nk);
        if (kwtuple == NULL) {
            result = NULL;
            goto done;
        }
        k = &PyTuple_GET_ITEM(kwtuple, 0);
        pos = i = 0;
        while (PyDict_Next(kwargs, &pos, &k[i], &k[i+1])) {
            Py_INCREF(k[i]);
            Py_INCREF(k[i+1]);
            i += 2;
        }
        nk = i / 2;
    }
    else {
        kwtuple = NULL;
        k = NULL;
    }
    closure = PyFunction_GET_CLOSURE(func);
#if PY_MAJOR_VERSION >= 3
    kwdefs = PyFunction_GET_KW_DEFAULTS(func);
#endif
    if (argdefs != NULL) {
        d = &PyTuple_GET_ITEM(argdefs, 0);
        nd = Py_SIZE(argdefs);
    }
    else {
        d = NULL;
        nd = 0;
    }
#if PY_MAJOR_VERSION >= 3
    result = PyEval_EvalCodeEx((PyObject*)co, globals, (PyObject *)NULL,
                               args, (int)nargs,
                               k, (int)nk,
                               d, (int)nd, kwdefs, closure);
#else
    result = PyEval_EvalCodeEx(co, globals, (PyObject *)NULL,
                               args, (int)nargs,
                               k, (int)nk,
                               d, (int)nd, closure);
#endif
    Py_XDECREF(kwtuple);
done:
    Py_LeaveRecursiveCall();
    return result;
}
#endif
#endif

/* PyObjectCall2Args */
static CYTHON_UNUSED PyObject* __Pyx_PyObject_Call2Args(PyObject* function, PyObject* arg1, PyObject* arg2) {
    PyObject *args, *result = NULL;
    #if CYTHON_FAST_PYCALL
    if (PyFunction_Check(function)) {
        PyObject *args[2] = {arg1, arg2};
        return __Pyx_PyFunction_FastCall(function, args, 2);
    }
    #endif
    #if CYTHON_FAST_PYCCALL
    if (__Pyx_PyFastCFunction_Check(function)) {
        PyObject *args[2] = {arg1, arg2};
        return __Pyx_PyCFunction_FastCall(function, args, 2);
    }
    #endif
    args = PyTuple_New(2);
    if (unlikely(!args)) goto done;
    Py_INCREF(arg1);
    PyTuple_SET_ITEM(args, 0, arg1);
    Py_INCREF(arg2);
    PyTuple_SET_ITEM(args, 1, arg2);
    Py_INCREF(function);
    result = __Pyx_PyObject_Call(function, args, NULL);
    Py_DECREF(args);
    Py_DECREF(function);
done:
    return result;
}

/* PyObjectCallMethO */
#if CYTHON_COMPILING_IN_CPYTHON
static CYTHON_INLINE PyObject* __Pyx_PyObject_CallMethO(PyObject *func, PyObject *arg) {
    PyObject *self, *result;
    PyCFunction cfunc;
    cfunc = PyCFunction_GET_FUNCTION(func);
    self = PyCFunction_GET_SELF(func);
    if (unlikely(Py_EnterRecursiveCall((char*)" while calling a Python object")))
        return NULL;
    result = cfunc(self, arg);
    Py_LeaveRecursiveCall();
    if (unlikely(!result) && unlikely(!PyErr_Occurred())) {
        PyErr_SetString(
            PyExc_SystemError,
            "NULL result without error in PyObject_Call");
    }
    return result;
}
#endif

/* PyObjectCallOneArg */
#if CYTHON_COMPILING_IN_CPYTHON
static PyObject* __Pyx__PyObject_CallOneArg(PyObject *func, PyObject *arg) {
    PyObject *result;
    PyObject *args = PyTuple_New(1);
    if (unlikely(!args)) return NULL;
    Py_INCREF(arg);
    PyTuple_SET_ITEM(args, 0, arg);
    result = __Pyx_PyObject_Call(func, args, NULL);
    Py_DECREF(args);
    return result;
}
static CYTHON_INLINE PyObject* __Pyx_PyObject_CallOneArg(PyObject *func, PyObject *arg) {
#if CYTHON_FAST_PYCALL
    if (PyFunction_Check(func)) {
        return __Pyx_PyFunction_FastCall(func, &arg, 1);
    }
#endif
    if (likely(PyCFunction_Check(func))) {
        if (likely(PyCFunction_GET_FLAGS(func) & METH_O)) {
            return __Pyx_PyObject_CallMethO(func, arg);
#if CYTHON_FAST_PYCCALL
        } else if (PyCFunction_GET_FLAGS(func) & METH_FASTCALL) {
            return __Pyx_PyCFunction_FastCall(func, &arg, 1);
#endif
        }
    }
    return __Pyx__PyObject_CallOneArg(func, arg);
}
#else
static CYTHON_INLINE PyObject* __Pyx_PyObject_CallOneArg(PyObject *func, PyObject *arg) {
    PyObject *result;
    PyObject *args = PyTuple_Pack(1, arg);
    if (unlikely(!args)) return NULL;
    result = __Pyx_PyObject_Call(func, args, NULL);
    Py_DECREF(args);
    return result;
}
#endif

/* PyIntCompare */
static CYTHON_INLINE PyObject* __Pyx_PyInt_NeObjC(PyObject *op1, PyObject *op2, CYTHON_UNUSED long intval, CYTHON_UNUSED long inplace) {
    if (op1 == op2) {
        Py_RETURN_FALSE;
    }
    #if PY_MAJOR_VERSION < 3
    if (likely(PyInt_CheckExact(op1))) {
        const long b = intval;
        long a = PyInt_AS_LONG(op1);
        if (a != b) Py_RETURN_TRUE; else Py_RETURN_FALSE;
    }
    #endif
    #if CYTHON_USE_PYLONG_INTERNALS
    if (likely(PyLong_CheckExact(op1))) {
        int unequal;
        unsigned long uintval;
        Py_ssize_t size = Py_SIZE(op1);
        const digit* digits = ((PyLongObject*)op1)->ob_digit;
        if (intval == 0) {
            if (size != 0) Py_RETURN_TRUE; else Py_RETURN_FALSE;
        } else if (intval < 0) {
            if (size >= 0)
                Py_RETURN_TRUE;
            intval = -intval;
            size = -size;
        } else {
            if (size <= 0)
                Py_RETURN_TRUE;
        }
        uintval = (unsigned long) intval;
#if PyLong_SHIFT * 4 < SIZEOF_LONG*8
        if (uintval >> (PyLong_SHIFT * 4)) {
            unequal = (size != 5) || (digits[0] != (uintval & (unsigned long) PyLong_MASK))
                 | (digits[1] != ((uintval >> (1 * PyLong_SHIFT)) & (unsigned long) PyLong_MASK)) | (digits[2] != ((uintval >> (2 * PyLong_SHIFT)) & (unsigned long) PyLong_MASK)) | (digits[3] != ((uintval >> (3 * PyLong_SHIFT)) & (unsigned long) PyLong_MASK)) | (digits[4] != ((uintval >> (4 * PyLong_SHIFT)) & (unsigned long) PyLong_MASK));
        } else
#endif
#if PyLong_SHIFT * 3 < SIZEOF_LONG*8
        if (uintval >> (PyLong_SHIFT * 3)) {
            unequal = (size != 4) || (digits[0] != (uintval & (unsigned long) PyLong_MASK))
                 | (digits[1] != ((uintval >> (1 * PyLong_SHIFT)) & (unsigned long) PyLong_MASK)) | (digits[2] != ((uintval >> (2 * PyLong_SHIFT)) & (unsigned long) PyLong_MASK)) | (digits[3] != ((uintval >> (3 * PyLong_SHIFT)) & (unsigned long) PyLong_MASK));
        } else
#endif
#if PyLong_SHIFT * 2 < SIZEOF_LONG*8
        if (uintval >> (PyLong_SHIFT * 2)) {
            unequal = (size != 3) || (digits[0] != (uintval & (unsigned long) PyLong_MASK))
                 | (digits[1] != ((uintval >> (1 * PyLong_SHIFT)) & (unsigned long) PyLong_MASK)) | (digits[2] != ((uintval >> (2 * PyLong_SHIFT)) & (unsigned long) PyLong_MASK));
        } else
#endif
#if PyLong_SHIFT * 1 < SIZEOF_LONG*8
        if (uintval >> (PyLong_SHIFT * 1)) {
            unequal = (size != 2) || (digits[0] != (uintval & (unsigned long) PyLong_MASK))
                 | (digits[1] != ((uintval >> (1 * PyLong_SHIFT)) & (unsigned long) PyLong_MASK));
        } else
#endif
            unequal = (size != 1) || (((unsigned long) digits[0]) != (uintval & (unsigned long) PyLong_MASK));
        if (unequal != 0) Py_RETURN_TRUE; else Py_RETURN_FALSE;
    }
    #endif
    if (PyFloat_CheckExact(op1)) {
        const long b = intval;
        double a = PyFloat_AS_DOUBLE(op1);
        if ((double)a != (double)b) Py_RETURN_TRUE; else Py_RETURN_FALSE;
    }
    return (
        PyObject_RichCompare(op1, op2, Py_NE));
}

/* PyObjectCallNoArg */
#if CYTHON_COMPILING_IN_CPYTHON
static CYTHON_INLINE PyObject* __Pyx_PyObject_CallNoArg(PyObject *func) {
#if CYTHON_FAST_PYCALL
    if (PyFunction_Check(func)) {
        return __Pyx_PyFunction_FastCall(func, NULL, 0);
    }
#endif
#ifdef __Pyx_CyFunction_USED
    if (likely(PyCFunction_Check(func) || __Pyx_CyFunction_Check(func)))
#else
    if (likely(PyCFunction_Check(func)))
#endif
    {
        if (likely(PyCFunction_GET_FLAGS(func) & METH_NOARGS)) {
            return __Pyx_PyObject_CallMethO(func, NULL);
        }
    }
    return __Pyx_PyObject_Call(func, __pyx_empty_tuple, NULL);
}
#endif

/* PyIntCompare */
static CYTHON_INLINE PyObject* __Pyx_PyInt_EqObjC(PyObject *op1, PyObject *op2, CYTHON_UNUSED long intval, CYTHON_UNUSED long inplace) {
    if (op1 == op2) {
        Py_RETURN_TRUE;
    }
    #if PY_MAJOR_VERSION < 3
    if (likely(PyInt_CheckExact(op1))) {
        const long b = intval;
        long a = PyInt_AS_LONG(op1);
        if (a == b) Py_RETURN_TRUE; else Py_RETURN_FALSE;
    }
    #endif
    #if CYTHON_USE_PYLONG_INTERNALS
    if (likely(PyLong_CheckExact(op1))) {
        int unequal;
        unsigned long uintval;
        Py_ssize_t size = Py_SIZE(op1);
        const digit* digits = ((PyLongObject*)op1)->ob_digit;
        if (intval == 0) {
            if (size == 0) Py_RETURN_TRUE; else Py_RETURN_FALSE;
        } else if (intval < 0) {
            if (size >= 0)
                Py_RETURN_FALSE;
            intval = -intval;
            size = -size;
        } else {
            if (size <= 0)
                Py_RETURN_FALSE;
        }
        uintval = (unsigned long) intval;
#if PyLong_SHIFT * 4 < SIZEOF_LONG*8
        if (uintval >> (PyLong_SHIFT * 4)) {
            unequal = (size != 5) || (digits[0] != (uintval & (unsigned long) PyLong_MASK))
                 | (digits[1] != ((uintval >> (1 * PyLong_SHIFT)) & (unsigned long) PyLong_MASK)) | (digits[2] != ((uintval >> (2 * PyLong_SHIFT)) & (unsigned long) PyLong_MASK)) | (digits[3] != ((uintval >> (3 * PyLong_SHIFT)) & (unsigned long) PyLong_MASK)) | (digits[4] != ((uintval >> (4 * PyLong_SHIFT)) & (unsigned long) PyLong_MASK));
        } else
#endif
#if PyLong_SHIFT * 3 < SIZEOF_LONG*8
        if (uintval >> (PyLong_SHIFT * 3)) {
            unequal = (size != 4) || (digits[0] != (uintval & (unsigned long) PyLong_MASK))
                 | (digits[1] != ((uintval >> (1 * PyLong_SHIFT)) & (unsigned long) PyLong_MASK)) | (digits[2] != ((uintval >> (2 * PyLong_SHIFT)) & (unsigned long) PyLong_MASK)) | (digits[3] != ((uintval >> (3 * PyLong_SHIFT)) & (unsigned long) PyLong_MASK));
        } else
#endif
#if PyLong_SHIFT * 2 < SIZEOF_LONG*8
        if (uintval >> (PyLong_SHIFT * 2)) {
            unequal = (size != 3) || (digits[0] != (uintval & (unsigned long) PyLong_MASK))
                 | (digits[1] != ((uintval >> (1 * PyLong_SHIFT)) & (unsigned long) PyLong_MASK)) | (digits[2] != ((uintval >> (2 * PyLong_SHIFT)) & (unsigned long) PyLong_MASK));
        } else
#endif
#if PyLong_SHIFT * 1 < SIZEOF_LONG*8
        if (uintval >> (PyLong_SHIFT * 1)) {
            unequal = (size != 2) || (digits[0] != (uintval & (unsigned long) PyLong_MASK))
                 | (digits[1] != ((uintval >> (1 * PyLong_SHIFT)) & (unsigned long) PyLong_MASK));
        } else
#endif
            unequal = (size != 1) || (((unsigned long) digits[0]) != (uintval & (unsigned long) PyLong_MASK));
        if (unequal == 0) Py_RETURN_TRUE; else Py_RETURN_FALSE;
    }
    #endif
    if (PyFloat_CheckExact(op1)) {
        const long b = intval;
        double a = PyFloat_AS_DOUBLE(op1);
        if ((double)a == (double)b) Py_RETURN_TRUE; else Py_RETURN_FALSE;
    }
    return (
        PyObject_RichCompare(op1, op2, Py_EQ));
}

/* GetItemInt */
static PyObject *__Pyx_GetItemInt_Generic(PyObject *o, PyObject* j) {
    PyObject *r;
    if (!j) return NULL;
    r = PyObject_GetItem(o, j);
    Py_DECREF(j);
    return r;
}
static CYTHON_INLINE PyObject *__Pyx_GetItemInt_List_Fast(PyObject *o, Py_ssize_t i,
                                                              CYTHON_NCP_UNUSED int wraparound,
                                                              CYTHON_NCP_UNUSED int boundscheck) {
#if CYTHON_ASSUME_SAFE_MACROS && !CYTHON_AVOID_BORROWED_REFS
    Py_ssize_t wrapped_i = i;
    if (wraparound & unlikely(i < 0)) {
        wrapped_i += PyList_GET_SIZE(o);
    }
    if ((!boundscheck) || likely(__Pyx_is_valid_index(wrapped_i, PyList_GET_SIZE(o)))) {
        PyObject *r = PyList_GET_ITEM(o, wrapped_i);
        Py_INCREF(r);
        return r;
    }
    return __Pyx_GetItemInt_Generic(o, PyInt_FromSsize_t(i));
#else
    return PySequence_GetItem(o, i);
#endif
}
static CYTHON_INLINE PyObject *__Pyx_GetItemInt_Tuple_Fast(PyObject *o, Py_ssize_t i,
                                                              CYTHON_NCP_UNUSED int wraparound,
                                                              CYTHON_NCP_UNUSED int boundscheck) {
#if CYTHON_ASSUME_SAFE_MACROS && !CYTHON_AVOID_BORROWED_REFS
    Py_ssize_t wrapped_i = i;
    if (wraparound & unlikely(i < 0)) {
        wrapped_i += PyTuple_GET_SIZE(o);
    }
    if ((!boundscheck) || likely(__Pyx_is_valid_index(wrapped_i, PyTuple_GET_SIZE(o)))) {
        PyObject *r = PyTuple_GET_ITEM(o, wrapped_i);
        Py_INCREF(r);
        return r;
    }
    return __Pyx_GetItemInt_Generic(o, PyInt_FromSsize_t(i));
#else
    return PySequence_GetItem(o, i);
#endif
}
static CYTHON_INLINE PyObject *__Pyx_GetItemInt_Fast(PyObject *o, Py_ssize_t i, int is_list,
                                                     CYTHON_NCP_UNUSED int wraparound,
                                                     CYTHON_NCP_UNUSED int boundscheck) {
#if CYTHON_ASSUME_SAFE_MACROS && !CYTHON_AVOID_BORROWED_REFS && CYTHON_USE_TYPE_SLOTS
    if (is_list || PyList_CheckExact(o)) {
        Py_ssize_t n = ((!wraparound) | likely(i >= 0)) ? i : i + PyList_GET_SIZE(o);
        if ((!boundscheck) || (likely(__Pyx_is_valid_index(n, PyList_GET_SIZE(o))))) {
            PyObject *r = PyList_GET_ITEM(o, n);
            Py_INCREF(r);
            return r;
        }
    }
    else if (PyTuple_CheckExact(o)) {
        Py_ssize_t n = ((!wraparound) | likely(i >= 0)) ? i : i + PyTuple_GET_SIZE(o);
        if ((!boundscheck) || likely(__Pyx_is_valid_index(n, PyTuple_GET_SIZE(o)))) {
            PyObject *r = PyTuple_GET_ITEM(o, n);
            Py_INCREF(r);
            return r;
        }
    } else {
        PySequenceMethods *m = Py_TYPE(o)->tp_as_sequence;
        if (likely(m && m->sq_item)) {
            if (wraparound && unlikely(i < 0) && likely(m->sq_length)) {
                Py_ssize_t l = m->sq_length(o);
                if (likely(l >= 0)) {
                    i += l;
                } else {
                    if (!PyErr_ExceptionMatches(PyExc_OverflowError))
                        return NULL;
                    PyErr_Clear();
                }
            }
            return m->sq_item(o, i);
        }
    }
#else
    if (is_list || PySequence_Check(o)) {
        return PySequence_GetItem(o, i);
    }
#endif
    return __Pyx_GetItemInt_Generic(o, PyInt_FromSsize_t(i));
}

/* SetItemInt */
static int __Pyx_SetItemInt_Generic(PyObject *o, PyObject *j, PyObject *v) {
    int r;
    if (!j) return -1;
    r = PyObject_SetItem(o, j, v);
    Py_DECREF(j);
    return r;
}
static CYTHON_INLINE int __Pyx_SetItemInt_Fast(PyObject *o, Py_ssize_t i, PyObject *v, int is_list,
                                               CYTHON_NCP_UNUSED int wraparound, CYTHON_NCP_UNUSED int boundscheck) {
#if CYTHON_ASSUME_SAFE_MACROS && !CYTHON_AVOID_BORROWED_REFS && CYTHON_USE_TYPE_SLOTS
    if (is_list || PyList_CheckExact(o)) {
        Py_ssize_t n = (!wraparound) ? i : ((likely(i >= 0)) ? i : i + PyList_GET_SIZE(o));
        if ((!boundscheck) || likely(__Pyx_is_valid_index(n, PyList_GET_SIZE(o)))) {
            PyObject* old = PyList_GET_ITEM(o, n);
            Py_INCREF(v);
            PyList_SET_ITEM(o, n, v);
            Py_DECREF(old);
            return 1;
        }
    } else {
        PySequenceMethods *m = Py_TYPE(o)->tp_as_sequence;
        if (likely(m && m->sq_ass_item)) {
            if (wraparound && unlikely(i < 0) && likely(m->sq_length)) {
                Py_ssize_t l = m->sq_length(o);
                if (likely(l >= 0)) {
                    i += l;
                } else {
                    if (!PyErr_ExceptionMatches(PyExc_OverflowError))
                        return -1;
                    PyErr_Clear();
                }
            }
            return m->sq_ass_item(o, i, v);
        }
    }
#else
#if CYTHON_COMPILING_IN_PYPY
    if (is_list || (PySequence_Check(o) && !PyDict_Check(o)))
#else
    if (is_list || PySequence_Check(o))
#endif
    {
        return PySequence_SetItem(o, i, v);
    }
#endif
    return __Pyx_SetItemInt_Generic(o, PyInt_FromSsize_t(i), v);
}

/* SliceObject */
static CYTHON_INLINE PyObject* __Pyx_PyObject_GetSlice(PyObject* obj,
        Py_ssize_t cstart, Py_ssize_t cstop,
        PyObject** _py_start, PyObject** _py_stop, PyObject** _py_slice,
        int has_cstart, int has_cstop, CYTHON_UNUSED int wraparound) {
#if CYTHON_USE_TYPE_SLOTS
    PyMappingMethods* mp;
#if PY_MAJOR_VERSION < 3
    PySequenceMethods* ms = Py_TYPE(obj)->tp_as_sequence;
    if (likely(ms && ms->sq_slice)) {
        if (!has_cstart) {
            if (_py_start && (*_py_start != Py_None)) {
                cstart = __Pyx_PyIndex_AsSsize_t(*_py_start);
                if ((cstart == (Py_ssize_t)-1) && PyErr_Occurred()) goto bad;
            } else
                cstart = 0;
        }
        if (!has_cstop) {
            if (_py_stop && (*_py_stop != Py_None)) {
                cstop = __Pyx_PyIndex_AsSsize_t(*_py_stop);
                if ((cstop == (Py_ssize_t)-1) && PyErr_Occurred()) goto bad;
            } else
                cstop = PY_SSIZE_T_MAX;
        }
        if (wraparound && unlikely((cstart < 0) | (cstop < 0)) && likely(ms->sq_length)) {
            Py_ssize_t l = ms->sq_length(obj);
            if (likely(l >= 0)) {
                if (cstop < 0) {
                    cstop += l;
                    if (cstop < 0) cstop = 0;
                }
                if (cstart < 0) {
                    cstart += l;
                    if (cstart < 0) cstart = 0;
                }
            } else {
                if (!PyErr_ExceptionMatches(PyExc_OverflowError))
                    goto bad;
                PyErr_Clear();
            }
        }
        return ms->sq_slice(obj, cstart, cstop);
    }
#endif
    mp = Py_TYPE(obj)->tp_as_mapping;
    if (likely(mp && mp->mp_subscript))
#endif
    {
        PyObject* result;
        PyObject *py_slice, *py_start, *py_stop;
        if (_py_slice) {
            py_slice = *_py_slice;
        } else {
            PyObject* owned_start = NULL;
            PyObject* owned_stop = NULL;
            if (_py_start) {
                py_start = *_py_start;
            } else {
                if (has_cstart) {
                    owned_start = py_start = PyInt_FromSsize_t(cstart);
                    if (unlikely(!py_start)) goto bad;
                } else
                    py_start = Py_None;
            }
            if (_py_stop) {
                py_stop = *_py_stop;
            } else {
                if (has_cstop) {
                    owned_stop = py_stop = PyInt_FromSsize_t(cstop);
                    if (unlikely(!py_stop)) {
                        Py_XDECREF(owned_start);
                        goto bad;
                    }
                } else
                    py_stop = Py_None;
            }
            py_slice = PySlice_New(py_start, py_stop, Py_None);
            Py_XDECREF(owned_start);
            Py_XDECREF(owned_stop);
            if (unlikely(!py_slice)) goto bad;
        }
#if CYTHON_USE_TYPE_SLOTS
        result = mp->mp_subscript(obj, py_slice);
#else
        result = PyObject_GetItem(obj, py_slice);
#endif
        if (!_py_slice) {
            Py_DECREF(py_slice);
        }
        return result;
    }
    PyErr_Format(PyExc_TypeError,
        "'%.200s' object is unsliceable", Py_TYPE(obj)->tp_name);
bad:
    return NULL;
}

/* None */
static CYTHON_INLINE void __Pyx_RaiseUnboundLocalError(const char *varname) {
    PyErr_Format(PyExc_UnboundLocalError, "local variable '%s' referenced before assignment", varname);
}

/* RaiseTooManyValuesToUnpack */
static CYTHON_INLINE void __Pyx_RaiseTooManyValuesError(Py_ssize_t expected) {
    PyErr_Format(PyExc_ValueError,
                 "too many values to unpack (expected %" CYTHON_FORMAT_SSIZE_T "d)", expected);
}

/* RaiseNeedMoreValuesToUnpack */
static CYTHON_INLINE void __Pyx_RaiseNeedMoreValuesError(Py_ssize_t index) {
    PyErr_Format(PyExc_ValueError,
                 "need more than %" CYTHON_FORMAT_SSIZE_T "d value%.1s to unpack",
                 index, (index == 1) ? "" : "s");
}

/* IterFinish */
static CYTHON_INLINE int __Pyx_IterFinish(void) {
#if CYTHON_FAST_THREAD_STATE
    PyThreadState *tstate = __Pyx_PyThreadState_Current;
    PyObject* exc_type = tstate->curexc_type;
    if (unlikely(exc_type)) {
        if (likely(__Pyx_PyErr_GivenExceptionMatches(exc_type, PyExc_StopIteration))) {
            PyObject *exc_value, *exc_tb;
            exc_value = tstate->curexc_value;
            exc_tb = tstate->curexc_traceback;
            tstate->curexc_type = 0;
            tstate->curexc_value = 0;
            tstate->curexc_traceback = 0;
            Py_DECREF(exc_type);
            Py_XDECREF(exc_value);
            Py_XDECREF(exc_tb);
            return 0;
        } else {
            return -1;
        }
    }
    return 0;
#else
    if (unlikely(PyErr_Occurred())) {
        if (likely(PyErr_ExceptionMatches(PyExc_StopIteration))) {
            PyErr_Clear();
            return 0;
        } else {
            return -1;
        }
    }
    return 0;
#endif
}

/* UnpackItemEndCheck */
static int __Pyx_IternextUnpackEndCheck(PyObject *retval, Py_ssize_t expected) {
    if (unlikely(retval)) {
        Py_DECREF(retval);
        __Pyx_RaiseTooManyValuesError(expected);
        return -1;
    } else {
        return __Pyx_IterFinish();
    }
    return 0;
}

/* ObjectGetItem */
#if CYTHON_USE_TYPE_SLOTS
static PyObject *__Pyx_PyObject_GetIndex(PyObject *obj, PyObject* index) {
    PyObject *runerr;
    Py_ssize_t key_value;
    PySequenceMethods *m = Py_TYPE(obj)->tp_as_sequence;
    if (unlikely(!(m && m->sq_item))) {
        PyErr_Format(PyExc_TypeError, "'%.200s' object is not subscriptable", Py_TYPE(obj)->tp_name);
        return NULL;
    }
    key_value = __Pyx_PyIndex_AsSsize_t(index);
    if (likely(key_value != -1 || !(runerr = PyErr_Occurred()))) {
        return __Pyx_GetItemInt_Fast(obj, key_value, 0, 1, 1);
    }
    if (PyErr_GivenExceptionMatches(runerr, PyExc_OverflowError)) {
        PyErr_Clear();
        PyErr_Format(PyExc_IndexError, "cannot fit '%.200s' into an index-sized integer", Py_TYPE(index)->tp_name);
    }
    return NULL;
}
static PyObject *__Pyx_PyObject_GetItem(PyObject *obj, PyObject* key) {
    PyMappingMethods *m = Py_TYPE(obj)->tp_as_mapping;
    if (likely(m && m->mp_subscript)) {
        return m->mp_subscript(obj, key);
    }
    return __Pyx_PyObject_GetIndex(obj, key);
}
#endif

/* RaiseArgTupleInvalid */
static void __Pyx_RaiseArgtupleInvalid(
    const char* func_name,
    int exact,
    Py_ssize_t num_min,
    Py_ssize_t num_max,
    Py_ssize_t num_found)
{
    Py_ssize_t num_expected;
    const char *more_or_less;
    if (num_found < num_min) {
        num_expected = num_min;
        more_or_less = "at least";
    } else {
        num_expected = num_max;
        more_or_less = "at most";
    }
    if (exact) {
        more_or_less = "exactly";
    }
    PyErr_Format(PyExc_TypeError,
                 "%.200s() takes %.8s %" CYTHON_FORMAT_SSIZE_T "d positional argument%.1s (%" CYTHON_FORMAT_SSIZE_T "d given)",
                 func_name, more_or_less, num_expected,
                 (num_expected == 1) ? "" : "s", num_found);
}

/* RaiseDoubleKeywords */
static void __Pyx_RaiseDoubleKeywordsError(
    const char* func_name,
    PyObject* kw_name)
{
    PyErr_Format(PyExc_TypeError,
        #if PY_MAJOR_VERSION >= 3
        "%s() got multiple values for keyword argument '%U'", func_name, kw_name);
        #else
        "%s() got multiple values for keyword argument '%s'", func_name,
        PyString_AsString(kw_name));
        #endif
}

/* ParseKeywords */
static int __Pyx_ParseOptionalKeywords(
    PyObject *kwds,
    PyObject **argnames[],
    PyObject *kwds2,
    PyObject *values[],
    Py_ssize_t num_pos_args,
    const char* function_name)
{
    PyObject *key = 0, *value = 0;
    Py_ssize_t pos = 0;
    PyObject*** name;
    PyObject*** first_kw_arg = argnames + num_pos_args;
    while (PyDict_Next(kwds, &pos, &key, &value)) {
        name = first_kw_arg;
        while (*name && (**name != key)) name++;
        if (*name) {
            values[name-argnames] = value;
            continue;
        }
        name = first_kw_arg;
        #if PY_MAJOR_VERSION < 3
        if (likely(PyString_CheckExact(key)) || likely(PyString_Check(key))) {
            while (*name) {
                if ((CYTHON_COMPILING_IN_PYPY || PyString_GET_SIZE(**name) == PyString_GET_SIZE(key))
                        && _PyString_Eq(**name, key)) {
                    values[name-argnames] = value;
                    break;
                }
                name++;
            }
            if (*name) continue;
            else {
                PyObject*** argname = argnames;
                while (argname != first_kw_arg) {
                    if ((**argname == key) || (
                            (CYTHON_COMPILING_IN_PYPY || PyString_GET_SIZE(**argname) == PyString_GET_SIZE(key))
                             && _PyString_Eq(**argname, key))) {
                        goto arg_passed_twice;
                    }
                    argname++;
                }
            }
        } else
        #endif
        if (likely(PyUnicode_Check(key))) {
            while (*name) {
                int cmp = (**name == key) ? 0 :
                #if !CYTHON_COMPILING_IN_PYPY && PY_MAJOR_VERSION >= 3
                    (PyUnicode_GET_SIZE(**name) != PyUnicode_GET_SIZE(key)) ? 1 :
                #endif
                    PyUnicode_Compare(**name, key);
                if (cmp < 0 && unlikely(PyErr_Occurred())) goto bad;
                if (cmp == 0) {
                    values[name-argnames] = value;
                    break;
                }
                name++;
            }
            if (*name) continue;
            else {
                PyObject*** argname = argnames;
                while (argname != first_kw_arg) {
                    int cmp = (**argname == key) ? 0 :
                    #if !CYTHON_COMPILING_IN_PYPY && PY_MAJOR_VERSION >= 3
                        (PyUnicode_GET_SIZE(**argname) != PyUnicode_GET_SIZE(key)) ? 1 :
                    #endif
                        PyUnicode_Compare(**argname, key);
                    if (cmp < 0 && unlikely(PyErr_Occurred())) goto bad;
                    if (cmp == 0) goto arg_passed_twice;
                    argname++;
                }
            }
        } else
            goto invalid_keyword_type;
        if (kwds2) {
            if (unlikely(PyDict_SetItem(kwds2, key, value))) goto bad;
        } else {
            goto invalid_keyword;
        }
    }
    return 0;
arg_passed_twice:
    __Pyx_RaiseDoubleKeywordsError(function_name, key);
    goto bad;
invalid_keyword_type:
    PyErr_Format(PyExc_TypeError,
        "%.200s() keywords must be strings", function_name);
    goto bad;
invalid_keyword:
    PyErr_Format(PyExc_TypeError,
    #if PY_MAJOR_VERSION < 3
        "%.200s() got an unexpected keyword argument '%.200s'",
        function_name, PyString_AsString(key));
    #else
        "%s() got an unexpected keyword argument '%U'",
        function_name, key);
    #endif
bad:
    return -1;
}

/* DictGetItem */
#if PY_MAJOR_VERSION >= 3 && !CYTHON_COMPILING_IN_PYPY
static PyObject *__Pyx_PyDict_GetItem(PyObject *d, PyObject* key) {
    PyObject *value;
    value = PyDict_GetItemWithError(d, key);
    if (unlikely(!value)) {
        if (!PyErr_Occurred()) {
            if (unlikely(PyTuple_Check(key))) {
                PyObject* args = PyTuple_Pack(1, key);
                if (likely(args)) {
                    PyErr_SetObject(PyExc_KeyError, args);
                    Py_DECREF(args);
                }
            } else {
                PyErr_SetObject(PyExc_KeyError, key);
            }
        }
        return NULL;
    }
    Py_INCREF(value);
    return value;
}
#endif

/* pyobject_as_double */
static double __Pyx__PyObject_AsDouble(PyObject* obj) {
    PyObject* float_value;
#if !CYTHON_USE_TYPE_SLOTS
    float_value = PyNumber_Float(obj);  if ((0)) goto bad;
#else
    PyNumberMethods *nb = Py_TYPE(obj)->tp_as_number;
    if (likely(nb) && likely(nb->nb_float)) {
        float_value = nb->nb_float(obj);
        if (likely(float_value) && unlikely(!PyFloat_Check(float_value))) {
            PyErr_Format(PyExc_TypeError,
                "__float__ returned non-float (type %.200s)",
                Py_TYPE(float_value)->tp_name);
            Py_DECREF(float_value);
            goto bad;
        }
    } else if (PyUnicode_CheckExact(obj) || PyBytes_CheckExact(obj)) {
#if PY_MAJOR_VERSION >= 3
        float_value = PyFloat_FromString(obj);
#else
        float_value = PyFloat_FromString(obj, 0);
#endif
    } else {
        PyObject* args = PyTuple_New(1);
        if (unlikely(!args)) goto bad;
        PyTuple_SET_ITEM(args, 0, obj);
        float_value = PyObject_Call((PyObject*)&PyFloat_Type, args, 0);
        PyTuple_SET_ITEM(args, 0, 0);
        Py_DECREF(args);
    }
#endif
    if (likely(float_value)) {
        double value = PyFloat_AS_DOUBLE(float_value);
        Py_DECREF(float_value);
        return value;
    }
bad:
    return (double)-1;
}

/* BufferIndexError */
static void __Pyx_RaiseBufferIndexError(int axis) {
  PyErr_Format(PyExc_IndexError,
     "Out of bounds on buffer access (axis %d)", axis);
}

/* MemviewSliceInit */
static int
__Pyx_init_memviewslice(struct __pyx_memoryview_obj *memview,
                        int ndim,
                        __Pyx_memviewslice *memviewslice,
                        int memview_is_new_reference)
{
    __Pyx_RefNannyDeclarations
    int i, retval=-1;
    Py_buffer *buf = &memview->view;
    __Pyx_RefNannySetupContext("init_memviewslice", 0);
    if (memviewslice->memview || memviewslice->data) {
        PyErr_SetString(PyExc_ValueError,
            "memviewslice is already initialized!");
        goto fail;
    }
    if (buf->strides) {
        for (i = 0; i < ndim; i++) {
            memviewslice->strides[i] = buf->strides[i];
        }
    } else {
        Py_ssize_t stride = buf->itemsize;
        for (i = ndim - 1; i >= 0; i--) {
            memviewslice->strides[i] = stride;
            stride *= buf->shape[i];
        }
    }
    for (i = 0; i < ndim; i++) {
        memviewslice->shape[i]   = buf->shape[i];
        if (buf->suboffsets) {
            memviewslice->suboffsets[i] = buf->suboffsets[i];
        } else {
            memviewslice->suboffsets[i] = -1;
        }
    }
    memviewslice->memview = memview;
    memviewslice->data = (char *)buf->buf;
    if (__pyx_add_acquisition_count(memview) == 0 && !memview_is_new_reference) {
        Py_INCREF(memview);
    }
    retval = 0;
    goto no_fail;
fail:
    memviewslice->memview = 0;
    memviewslice->data = 0;
    retval = -1;
no_fail:
    __Pyx_RefNannyFinishContext();
    return retval;
}
#ifndef Py_NO_RETURN
#define Py_NO_RETURN
#endif
static void __pyx_fatalerror(const char *fmt, ...) Py_NO_RETURN {
    va_list vargs;
    char msg[200];
#ifdef HAVE_STDARG_PROTOTYPES
    va_start(vargs, fmt);
#else
    va_start(vargs);
#endif
    vsnprintf(msg, 200, fmt, vargs);
    va_end(vargs);
    Py_FatalError(msg);
}
static CYTHON_INLINE int
__pyx_add_acquisition_count_locked(__pyx_atomic_int *acquisition_count,
                                   PyThread_type_lock lock)
{
    int result;
    PyThread_acquire_lock(lock, 1);
    result = (*acquisition_count)++;
    PyThread_release_lock(lock);
    return result;
}
static CYTHON_INLINE int
__pyx_sub_acquisition_count_locked(__pyx_atomic_int *acquisition_count,
                                   PyThread_type_lock lock)
{
    int result;
    PyThread_acquire_lock(lock, 1);
    result = (*acquisition_count)--;
    PyThread_release_lock(lock);
    return result;
}
static CYTHON_INLINE void
__Pyx_INC_MEMVIEW(__Pyx_memviewslice *memslice, int have_gil, int lineno)
{
    int first_time;
    struct __pyx_memoryview_obj *memview = memslice->memview;
    if (!memview || (PyObject *) memview == Py_None)
        return;
    if (__pyx_get_slice_count(memview) < 0)
        __pyx_fatalerror("Acquisition count is %d (line %d)",
                         __pyx_get_slice_count(memview), lineno);
    first_time = __pyx_add_acquisition_count(memview) == 0;
    if (first_time) {
        if (have_gil) {
            Py_INCREF((PyObject *) memview);
        } else {
            PyGILState_STATE _gilstate = PyGILState_Ensure();
            Py_INCREF((PyObject *) memview);
            PyGILState_Release(_gilstate);
        }
    }
}
static CYTHON_INLINE void __Pyx_XDEC_MEMVIEW(__Pyx_memviewslice *memslice,
                                             int have_gil, int lineno) {
    int last_time;
    struct __pyx_memoryview_obj *memview = memslice->memview;
    if (!memview ) {
        return;
    } else if ((PyObject *) memview == Py_None) {
        memslice->memview = NULL;
        return;
    }
    if (__pyx_get_slice_count(memview) <= 0)
        __pyx_fatalerror("Acquisition count is %d (line %d)",
                         __pyx_get_slice_count(memview), lineno);
    last_time = __pyx_sub_acquisition_count(memview) == 1;
    memslice->data = NULL;
    if (last_time) {
        if (have_gil) {
            Py_CLEAR(memslice->memview);
        } else {
            PyGILState_STATE _gilstate = PyGILState_Ensure();
            Py_CLEAR(memslice->memview);
            PyGILState_Release(_gilstate);
        }
    } else {
        memslice->memview = NULL;
    }
}

/* BytesEquals */
static CYTHON_INLINE int __Pyx_PyBytes_Equals(PyObject* s1, PyObject* s2, int equals) {
#if CYTHON_COMPILING_IN_PYPY
    return PyObject_RichCompareBool(s1, s2, equals);
#else
    if (s1 == s2) {
        return (equals == Py_EQ);
    } else if (PyBytes_CheckExact(s1) & PyBytes_CheckExact(s2)) {
        const char *ps1, *ps2;
        Py_ssize_t length = PyBytes_GET_SIZE(s1);
        if (length != PyBytes_GET_SIZE(s2))
            return (equals == Py_NE);
        ps1 = PyBytes_AS_STRING(s1);
        ps2 = PyBytes_AS_STRING(s2);
        if (ps1[0] != ps2[0]) {
            return (equals == Py_NE);
        } else if (length == 1) {
            return (equals == Py_EQ);
        } else {
            int result;
#if CYTHON_USE_UNICODE_INTERNALS
            Py_hash_t hash1, hash2;
            hash1 = ((PyBytesObject*)s1)->ob_shash;
            hash2 = ((PyBytesObject*)s2)->ob_shash;
            if (hash1 != hash2 && hash1 != -1 && hash2 != -1) {
                return (equals == Py_NE);
            }
#endif
            result = memcmp(ps1, ps2, (size_t)length);
            return (equals == Py_EQ) ? (result == 0) : (result != 0);
        }
    } else if ((s1 == Py_None) & PyBytes_CheckExact(s2)) {
        return (equals == Py_NE);
    } else if ((s2 == Py_None) & PyBytes_CheckExact(s1)) {
        return (equals == Py_NE);
    } else {
        int result;
        PyObject* py_result = PyObject_RichCompare(s1, s2, equals);
        if (!py_result)
            return -1;
        result = __Pyx_PyObject_IsTrue(py_result);
        Py_DECREF(py_result);
        return result;
    }
#endif
}

/* UnicodeEquals */
static CYTHON_INLINE int __Pyx_PyUnicode_Equals(PyObject* s1, PyObject* s2, int equals) {
#if CYTHON_COMPILING_IN_PYPY
    return PyObject_RichCompareBool(s1, s2, equals);
#else
#if PY_MAJOR_VERSION < 3
    PyObject* owned_ref = NULL;
#endif
    int s1_is_unicode, s2_is_unicode;
    if (s1 == s2) {
        goto return_eq;
    }
    s1_is_unicode = PyUnicode_CheckExact(s1);
    s2_is_unicode = PyUnicode_CheckExact(s2);
#if PY_MAJOR_VERSION < 3
    if ((s1_is_unicode & (!s2_is_unicode)) && PyString_CheckExact(s2)) {
        owned_ref = PyUnicode_FromObject(s2);
        if (unlikely(!owned_ref))
            return -1;
        s2 = owned_ref;
        s2_is_unicode = 1;
    } else if ((s2_is_unicode & (!s1_is_unicode)) && PyString_CheckExact(s1)) {
        owned_ref = PyUnicode_FromObject(s1);
        if (unlikely(!owned_ref))
            return -1;
        s1 = owned_ref;
        s1_is_unicode = 1;
    } else if (((!s2_is_unicode) & (!s1_is_unicode))) {
        return __Pyx_PyBytes_Equals(s1, s2, equals);
    }
#endif
    if (s1_is_unicode & s2_is_unicode) {
        Py_ssize_t length;
        int kind;
        void *data1, *data2;
        if (unlikely(__Pyx_PyUnicode_READY(s1) < 0) || unlikely(__Pyx_PyUnicode_READY(s2) < 0))
            return -1;
        length = __Pyx_PyUnicode_GET_LENGTH(s1);
        if (length != __Pyx_PyUnicode_GET_LENGTH(s2)) {
            goto return_ne;
        }
#if CYTHON_USE_UNICODE_INTERNALS
        {
            Py_hash_t hash1, hash2;
        #if CYTHON_PEP393_ENABLED
            hash1 = ((PyASCIIObject*)s1)->hash;
            hash2 = ((PyASCIIObject*)s2)->hash;
        #else
            hash1 = ((PyUnicodeObject*)s1)->hash;
            hash2 = ((PyUnicodeObject*)s2)->hash;
        #endif
            if (hash1 != hash2 && hash1 != -1 && hash2 != -1) {
                goto return_ne;
            }
        }
#endif
        kind = __Pyx_PyUnicode_KIND(s1);
        if (kind != __Pyx_PyUnicode_KIND(s2)) {
            goto return_ne;
        }
        data1 = __Pyx_PyUnicode_DATA(s1);
        data2 = __Pyx_PyUnicode_DATA(s2);
        if (__Pyx_PyUnicode_READ(kind, data1, 0) != __Pyx_PyUnicode_READ(kind, data2, 0)) {
            goto return_ne;
        } else if (length == 1) {
            goto return_eq;
        } else {
            int result = memcmp(data1, data2, (size_t)(length * kind));
            #if PY_MAJOR_VERSION < 3
            Py_XDECREF(owned_ref);
            #endif
            return (equals == Py_EQ) ? (result == 0) : (result != 0);
        }
    } else if ((s1 == Py_None) & s2_is_unicode) {
        goto return_ne;
    } else if ((s2 == Py_None) & s1_is_unicode) {
        goto return_ne;
    } else {
        int result;
        PyObject* py_result = PyObject_RichCompare(s1, s2, equals);
        #if PY_MAJOR_VERSION < 3
        Py_XDECREF(owned_ref);
        #endif
        if (!py_result)
            return -1;
        result = __Pyx_PyObject_IsTrue(py_result);
        Py_DECREF(py_result);
        return result;
    }
return_eq:
    #if PY_MAJOR_VERSION < 3
    Py_XDECREF(owned_ref);
    #endif
    return (equals == Py_EQ);
return_ne:
    #if PY_MAJOR_VERSION < 3
    Py_XDECREF(owned_ref);
    #endif
    return (equals == Py_NE);
#endif
}

/* PyIntBinop */
#if !CYTHON_COMPILING_IN_PYPY
static PyObject* __Pyx_PyInt_SubtractCObj(PyObject *op1, PyObject *op2, CYTHON_UNUSED long intval, int inplace, int zerodivision_check) {
    (void)inplace;
    (void)zerodivision_check;
    #if PY_MAJOR_VERSION < 3
    if (likely(PyInt_CheckExact(op2))) {
        const long a = intval;
        long x;
        long b = PyInt_AS_LONG(op2);
            x = (long)((unsigned long)a - b);
            if (likely((x^a) >= 0 || (x^~b) >= 0))
                return PyInt_FromLong(x);
            return PyLong_Type.tp_as_number->nb_subtract(op1, op2);
    }
    #endif
    #if CYTHON_USE_PYLONG_INTERNALS
    if (likely(PyLong_CheckExact(op2))) {
        const long a = intval;
        long b, x;
#ifdef HAVE_LONG_LONG
        const PY_LONG_LONG lla = intval;
        PY_LONG_LONG llb, llx;
#endif
        const digit* digits = ((PyLongObject*)op2)->ob_digit;
        const Py_ssize_t size = Py_SIZE(op2);
        if (likely(__Pyx_sst_abs(size) <= 1)) {
            b = likely(size) ? digits[0] : 0;
            if (size == -1) b = -b;
        } else {
            switch (size) {
                case -2:
                    if (8 * sizeof(long) - 1 > 2 * PyLong_SHIFT) {
                        b = -(long) (((((unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0]));
                        break;
#ifdef HAVE_LONG_LONG
                    } else if (8 * sizeof(PY_LONG_LONG) - 1 > 2 * PyLong_SHIFT) {
                        llb = -(PY_LONG_LONG) (((((unsigned PY_LONG_LONG)digits[1]) << PyLong_SHIFT) | (unsigned PY_LONG_LONG)digits[0]));
                        goto long_long;
#endif
                    }
                    CYTHON_FALLTHROUGH;
                case 2:
                    if (8 * sizeof(long) - 1 > 2 * PyLong_SHIFT) {
                        b = (long) (((((unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0]));
                        break;
#ifdef HAVE_LONG_LONG
                    } else if (8 * sizeof(PY_LONG_LONG) - 1 > 2 * PyLong_SHIFT) {
                        llb = (PY_LONG_LONG) (((((unsigned PY_LONG_LONG)digits[1]) << PyLong_SHIFT) | (unsigned PY_LONG_LONG)digits[0]));
                        goto long_long;
#endif
                    }
                    CYTHON_FALLTHROUGH;
                case -3:
                    if (8 * sizeof(long) - 1 > 3 * PyLong_SHIFT) {
                        b = -(long) (((((((unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0]));
                        break;
#ifdef HAVE_LONG_LONG
                    } else if (8 * sizeof(PY_LONG_LONG) - 1 > 3 * PyLong_SHIFT) {
                        llb = -(PY_LONG_LONG) (((((((unsigned PY_LONG_LONG)digits[2]) << PyLong_SHIFT) | (unsigned PY_LONG_LONG)digits[1]) << PyLong_SHIFT) | (unsigned PY_LONG_LONG)digits[0]));
                        goto long_long;
#endif
                    }
                    CYTHON_FALLTHROUGH;
                case 3:
                    if (8 * sizeof(long) - 1 > 3 * PyLong_SHIFT) {
                        b = (long) (((((((unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0]));
                        break;
#ifdef HAVE_LONG_LONG
                    } else if (8 * sizeof(PY_LONG_LONG) - 1 > 3 * PyLong_SHIFT) {
                        llb = (PY_LONG_LONG) (((((((unsigned PY_LONG_LONG)digits[2]) << PyLong_SHIFT) | (unsigned PY_LONG_LONG)digits[1]) << PyLong_SHIFT) | (unsigned PY_LONG_LONG)digits[0]));
                        goto long_long;
#endif
                    }
                    CYTHON_FALLTHROUGH;
                case -4:
                    if (8 * sizeof(long) - 1 > 4 * PyLong_SHIFT) {
                        b = -(long) (((((((((unsigned long)digits[3]) << PyLong_SHIFT) | (unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0]));
                        break;
#ifdef HAVE_LONG_LONG
                    } else if (8 * sizeof(PY_LONG_LONG) - 1 > 4 * PyLong_SHIFT) {
                        llb = -(PY_LONG_LONG) (((((((((unsigned PY_LONG_LONG)digits[3]) << PyLong_SHIFT) | (unsigned PY_LONG_LONG)digits[2]) << PyLong_SHIFT) | (unsigned PY_LONG_LONG)digits[1]) << PyLong_SHIFT) | (unsigned PY_LONG_LONG)digits[0]));
                        goto long_long;
#endif
                    }
                    CYTHON_FALLTHROUGH;
                case 4:
                    if (8 * sizeof(long) - 1 > 4 * PyLong_SHIFT) {
                        b = (long) (((((((((unsigned long)digits[3]) << PyLong_SHIFT) | (unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0]));
                        break;
#ifdef HAVE_LONG_LONG
                    } else if (8 * sizeof(PY_LONG_LONG) - 1 > 4 * PyLong_SHIFT) {
                        llb = (PY_LONG_LONG) (((((((((unsigned PY_LONG_LONG)digits[3]) << PyLong_SHIFT) | (unsigned PY_LONG_LONG)digits[2]) << PyLong_SHIFT) | (unsigned PY_LONG_LONG)digits[1]) << PyLong_SHIFT) | (unsigned PY_LONG_LONG)digits[0]));
                        goto long_long;
#endif
                    }
                    CYTHON_FALLTHROUGH;
                default: return PyLong_Type.tp_as_number->nb_subtract(op1, op2);
            }
        }
                x = a - b;
            return PyLong_FromLong(x);
#ifdef HAVE_LONG_LONG
        long_long:
                llx = lla - llb;
            return PyLong_FromLongLong(llx);
#endif
        
        
    }
    #endif
    if (PyFloat_CheckExact(op2)) {
        const long a = intval;
        double b = PyFloat_AS_DOUBLE(op2);
            double result;
            PyFPE_START_PROTECT("subtract", return NULL)
            result = ((double)a) - (double)b;
            PyFPE_END_PROTECT(result)
            return PyFloat_FromDouble(result);
    }
    return (inplace ? PyNumber_InPlaceSubtract : PyNumber_Subtract)(op1, op2);
}
#endif

/* PyIntBinop */
#if !CYTHON_COMPILING_IN_PYPY
#if PY_MAJOR_VERSION < 3 || CYTHON_USE_PYLONG_INTERNALS
#define __Pyx_PyInt_TrueDivideObjC_ZeroDivisionError(operand)\
    if (unlikely(zerodivision_check && ((operand) == 0))) {\
        PyErr_SetString(PyExc_ZeroDivisionError, "integer division by zero");\
        return NULL;\
    }
#endif
static PyObject* __Pyx_PyInt_TrueDivideObjC(PyObject *op1, PyObject *op2, CYTHON_UNUSED long intval, int inplace, int zerodivision_check) {
    (void)inplace;
    (void)zerodivision_check;
    #if PY_MAJOR_VERSION < 3
    if (likely(PyInt_CheckExact(op1))) {
        const long b = intval;
        long a = PyInt_AS_LONG(op1);
            __Pyx_PyInt_TrueDivideObjC_ZeroDivisionError(b)
            if (8 * sizeof(long) <= 53 || likely(labs(a) <= ((PY_LONG_LONG)1 << 53))) {
                return PyFloat_FromDouble((double)a / (double)b);
            }
            return PyInt_Type.tp_as_number->nb_true_divide(op1, op2);
    }
    #endif
    #if CYTHON_USE_PYLONG_INTERNALS
    if (likely(PyLong_CheckExact(op1))) {
        const long b = intval;
        long a, x;
        const digit* digits = ((PyLongObject*)op1)->ob_digit;
        const Py_ssize_t size = Py_SIZE(op1);
        if (likely(__Pyx_sst_abs(size) <= 1)) {
            a = likely(size) ? digits[0] : 0;
            if (size == -1) a = -a;
        } else {
            switch (size) {
                case -2:
                    if (8 * sizeof(long) - 1 > 2 * PyLong_SHIFT && 1 * PyLong_SHIFT < 53) {
                        a = -(long) (((((unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0]));
                        break;
                    }
                    CYTHON_FALLTHROUGH;
                case 2:
                    if (8 * sizeof(long) - 1 > 2 * PyLong_SHIFT && 1 * PyLong_SHIFT < 53) {
                        a = (long) (((((unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0]));
                        break;
                    }
                    CYTHON_FALLTHROUGH;
                case -3:
                    if (8 * sizeof(long) - 1 > 3 * PyLong_SHIFT && 2 * PyLong_SHIFT < 53) {
                        a = -(long) (((((((unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0]));
                        break;
                    }
                    CYTHON_FALLTHROUGH;
                case 3:
                    if (8 * sizeof(long) - 1 > 3 * PyLong_SHIFT && 2 * PyLong_SHIFT < 53) {
                        a = (long) (((((((unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0]));
                        break;
                    }
                    CYTHON_FALLTHROUGH;
                case -4:
                    if (8 * sizeof(long) - 1 > 4 * PyLong_SHIFT && 3 * PyLong_SHIFT < 53) {
                        a = -(long) (((((((((unsigned long)digits[3]) << PyLong_SHIFT) | (unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0]));
                        break;
                    }
                    CYTHON_FALLTHROUGH;
                case 4:
                    if (8 * sizeof(long) - 1 > 4 * PyLong_SHIFT && 3 * PyLong_SHIFT < 53) {
                        a = (long) (((((((((unsigned long)digits[3]) << PyLong_SHIFT) | (unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0]));
                        break;
                    }
                    CYTHON_FALLTHROUGH;
                default: return PyLong_Type.tp_as_number->nb_true_divide(op1, op2);
            }
        }
                __Pyx_PyInt_TrueDivideObjC_ZeroDivisionError(b)
                if ((8 * sizeof(long) <= 53 || likely(labs(a) <= ((PY_LONG_LONG)1 << 53)))
                        || __Pyx_sst_abs(size) <= 52 / PyLong_SHIFT) {
                    return PyFloat_FromDouble((double)a / (double)b);
                }
                return PyLong_Type.tp_as_number->nb_true_divide(op1, op2);
            return PyLong_FromLong(x);
        
    }
    #endif
    if (PyFloat_CheckExact(op1)) {
        const long b = intval;
        double a = PyFloat_AS_DOUBLE(op1);
            double result;
            if (unlikely(zerodivision_check && b == 0)) {
                PyErr_SetString(PyExc_ZeroDivisionError, "float division by zero");
                return NULL;
            }
            PyFPE_START_PROTECT("divide", return NULL)
            result = ((double)a) / (double)b;
            PyFPE_END_PROTECT(result)
            return PyFloat_FromDouble(result);
    }
    return (inplace ? PyNumber_InPlaceTrueDivide : PyNumber_TrueDivide)(op1, op2);
}
#endif

/* PyObjectGetMethod */
static int __Pyx_PyObject_GetMethod(PyObject *obj, PyObject *name, PyObject **method) {
    PyObject *attr;
#if CYTHON_UNPACK_METHODS && CYTHON_COMPILING_IN_CPYTHON && CYTHON_USE_PYTYPE_LOOKUP
    PyTypeObject *tp = Py_TYPE(obj);
    PyObject *descr;
    descrgetfunc f = NULL;
    PyObject **dictptr, *dict;
    int meth_found = 0;
    assert (*method == NULL);
    if (unlikely(tp->tp_getattro != PyObject_GenericGetAttr)) {
        attr = __Pyx_PyObject_GetAttrStr(obj, name);
        goto try_unpack;
    }
    if (unlikely(tp->tp_dict == NULL) && unlikely(PyType_Ready(tp) < 0)) {
        return 0;
    }
    descr = _PyType_Lookup(tp, name);
    if (likely(descr != NULL)) {
        Py_INCREF(descr);
#if PY_MAJOR_VERSION >= 3
        #ifdef __Pyx_CyFunction_USED
        if (likely(PyFunction_Check(descr) || (Py_TYPE(descr) == &PyMethodDescr_Type) || __Pyx_CyFunction_Check(descr)))
        #else
        if (likely(PyFunction_Check(descr) || (Py_TYPE(descr) == &PyMethodDescr_Type)))
        #endif
#else
        #ifdef __Pyx_CyFunction_USED
        if (likely(PyFunction_Check(descr) || __Pyx_CyFunction_Check(descr)))
        #else
        if (likely(PyFunction_Check(descr)))
        #endif
#endif
        {
            meth_found = 1;
        } else {
            f = Py_TYPE(descr)->tp_descr_get;
            if (f != NULL && PyDescr_IsData(descr)) {
                attr = f(descr, obj, (PyObject *)Py_TYPE(obj));
                Py_DECREF(descr);
                goto try_unpack;
            }
        }
    }
    dictptr = _PyObject_GetDictPtr(obj);
    if (dictptr != NULL && (dict = *dictptr) != NULL) {
        Py_INCREF(dict);
        attr = __Pyx_PyDict_GetItemStr(dict, name);
        if (attr != NULL) {
            Py_INCREF(attr);
            Py_DECREF(dict);
            Py_XDECREF(descr);
            goto try_unpack;
        }
        Py_DECREF(dict);
    }
    if (meth_found) {
        *method = descr;
        return 1;
    }
    if (f != NULL) {
        attr = f(descr, obj, (PyObject *)Py_TYPE(obj));
        Py_DECREF(descr);
        goto try_unpack;
    }
    if (descr != NULL) {
        *method = descr;
        return 0;
    }
    PyErr_Format(PyExc_AttributeError,
#if PY_MAJOR_VERSION >= 3
                 "'%.50s' object has no attribute '%U'",
                 tp->tp_name, name);
#else
                 "'%.50s' object has no attribute '%.400s'",
                 tp->tp_name, PyString_AS_STRING(name));
#endif
    return 0;
#else
    attr = __Pyx_PyObject_GetAttrStr(obj, name);
    goto try_unpack;
#endif
try_unpack:
#if CYTHON_UNPACK_METHODS
    if (likely(attr) && PyMethod_Check(attr) && likely(PyMethod_GET_SELF(attr) == obj)) {
        PyObject *function = PyMethod_GET_FUNCTION(attr);
        Py_INCREF(function);
        Py_DECREF(attr);
        *method = function;
        return 1;
    }
#endif
    *method = attr;
    return 0;
}

/* PyObjectCallMethod1 */
static PyObject* __Pyx__PyObject_CallMethod1(PyObject* method, PyObject* arg) {
    PyObject *result = __Pyx_PyObject_CallOneArg(method, arg);
    Py_DECREF(method);
    return result;
}
static PyObject* __Pyx_PyObject_CallMethod1(PyObject* obj, PyObject* method_name, PyObject* arg) {
    PyObject *method = NULL, *result;
    int is_method = __Pyx_PyObject_GetMethod(obj, method_name, &method);
    if (likely(is_method)) {
        result = __Pyx_PyObject_Call2Args(method, obj, arg);
        Py_DECREF(method);
        return result;
    }
    if (unlikely(!method)) return NULL;
    return __Pyx__PyObject_CallMethod1(method, arg);
}

/* append */
static CYTHON_INLINE int __Pyx_PyObject_Append(PyObject* L, PyObject* x) {
    if (likely(PyList_CheckExact(L))) {
        if (unlikely(__Pyx_PyList_Append(L, x) < 0)) return -1;
    } else {
        PyObject* retval = __Pyx_PyObject_CallMethod1(L, __pyx_n_s_append, x);
        if (unlikely(!retval))
            return -1;
        Py_DECREF(retval);
    }
    return 0;
}

/* ArgTypeTest */
static int __Pyx__ArgTypeTest(PyObject *obj, PyTypeObject *type, const char *name, int exact)
{
    if (unlikely(!type)) {
        PyErr_SetString(PyExc_SystemError, "Missing type object");
        return 0;
    }
    else if (exact) {
        #if PY_MAJOR_VERSION == 2
        if ((type == &PyBaseString_Type) && likely(__Pyx_PyBaseString_CheckExact(obj))) return 1;
        #endif
    }
    else {
        if (likely(__Pyx_TypeCheck(obj, type))) return 1;
    }
    PyErr_Format(PyExc_TypeError,
        "Argument '%.200s' has incorrect type (expected %.200s, got %.200s)",
        name, type->tp_name, Py_TYPE(obj)->tp_name);
    return 0;
}

/* PyErrFetchRestore */
#if CYTHON_FAST_THREAD_STATE
static CYTHON_INLINE void __Pyx_ErrRestoreInState(PyThreadState *tstate, PyObject *type, PyObject *value, PyObject *tb) {
    PyObject *tmp_type, *tmp_value, *tmp_tb;
    tmp_type = tstate->curexc_type;
    tmp_value = tstate->curexc_value;
    tmp_tb = tstate->curexc_traceback;
    tstate->curexc_type = type;
    tstate->curexc_value = value;
    tstate->curexc_traceback = tb;
    Py_XDECREF(tmp_type);
    Py_XDECREF(tmp_value);
    Py_XDECREF(tmp_tb);
}
static CYTHON_INLINE void __Pyx_ErrFetchInState(PyThreadState *tstate, PyObject **type, PyObject **value, PyObject **tb) {
    *type = tstate->curexc_type;
    *value = tstate->curexc_value;
    *tb = tstate->curexc_traceback;
    tstate->curexc_type = 0;
    tstate->curexc_value = 0;
    tstate->curexc_traceback = 0;
}
#endif

/* RaiseException */
#if PY_MAJOR_VERSION < 3
static void __Pyx_Raise(PyObject *type, PyObject *value, PyObject *tb,
                        CYTHON_UNUSED PyObject *cause) {
    __Pyx_PyThreadState_declare
    Py_XINCREF(type);
    if (!value || value == Py_None)
        value = NULL;
    else
        Py_INCREF(value);
    if (!tb || tb == Py_None)
        tb = NULL;
    else {
        Py_INCREF(tb);
        if (!PyTraceBack_Check(tb)) {
            PyErr_SetString(PyExc_TypeError,
                "raise: arg 3 must be a traceback or None");
            goto raise_error;
        }
    }
    if (PyType_Check(type)) {
#if CYTHON_COMPILING_IN_PYPY
        if (!value) {
            Py_INCREF(Py_None);
            value = Py_None;
        }
#endif
        PyErr_NormalizeException(&type, &value, &tb);
    } else {
        if (value) {
            PyErr_SetString(PyExc_TypeError,
                "instance exception may not have a separate value");
            goto raise_error;
        }
        value = type;
        type = (PyObject*) Py_TYPE(type);
        Py_INCREF(type);
        if (!PyType_IsSubtype((PyTypeObject *)type, (PyTypeObject *)PyExc_BaseException)) {
            PyErr_SetString(PyExc_TypeError,
                "raise: exception class must be a subclass of BaseException");
            goto raise_error;
        }
    }
    __Pyx_PyThreadState_assign
    __Pyx_ErrRestore(type, value, tb);
    return;
raise_error:
    Py_XDECREF(value);
    Py_XDECREF(type);
    Py_XDECREF(tb);
    return;
}
#else
static void __Pyx_Raise(PyObject *type, PyObject *value, PyObject *tb, PyObject *cause) {
    PyObject* owned_instance = NULL;
    if (tb == Py_None) {
        tb = 0;
    } else if (tb && !PyTraceBack_Check(tb)) {
        PyErr_SetString(PyExc_TypeError,
            "raise: arg 3 must be a traceback or None");
        goto bad;
    }
    if (value == Py_None)
        value = 0;
    if (PyExceptionInstance_Check(type)) {
        if (value) {
            PyErr_SetString(PyExc_TypeError,
                "instance exception may not have a separate value");
            goto bad;
        }
        value = type;
        type = (PyObject*) Py_TYPE(value);
    } else if (PyExceptionClass_Check(type)) {
        PyObject *instance_class = NULL;
        if (value && PyExceptionInstance_Check(value)) {
            instance_class = (PyObject*) Py_TYPE(value);
            if (instance_class != type) {
                int is_subclass = PyObject_IsSubclass(instance_class, type);
                if (!is_subclass) {
                    instance_class = NULL;
                } else if (unlikely(is_subclass == -1)) {
                    goto bad;
                } else {
                    type = instance_class;
                }
            }
        }
        if (!instance_class) {
            PyObject *args;
            if (!value)
                args = PyTuple_New(0);
            else if (PyTuple_Check(value)) {
                Py_INCREF(value);
                args = value;
            } else
                args = PyTuple_Pack(1, value);
            if (!args)
                goto bad;
            owned_instance = PyObject_Call(type, args, NULL);
            Py_DECREF(args);
            if (!owned_instance)
                goto bad;
            value = owned_instance;
            if (!PyExceptionInstance_Check(value)) {
                PyErr_Format(PyExc_TypeError,
                             "calling %R should have returned an instance of "
                             "BaseException, not %R",
                             type, Py_TYPE(value));
                goto bad;
            }
        }
    } else {
        PyErr_SetString(PyExc_TypeError,
            "raise: exception class must be a subclass of BaseException");
        goto bad;
    }
    if (cause) {
        PyObject *fixed_cause;
        if (cause == Py_None) {
            fixed_cause = NULL;
        } else if (PyExceptionClass_Check(cause)) {
            fixed_cause = PyObject_CallObject(cause, NULL);
            if (fixed_cause == NULL)
                goto bad;
        } else if (PyExceptionInstance_Check(cause)) {
            fixed_cause = cause;
            Py_INCREF(fixed_cause);
        } else {
            PyErr_SetString(PyExc_TypeError,
                            "exception causes must derive from "
                            "BaseException");
            goto bad;
        }
        PyException_SetCause(value, fixed_cause);
    }
    PyErr_SetObject(type, value);
    if (tb) {
#if CYTHON_COMPILING_IN_PYPY
        PyObject *tmp_type, *tmp_value, *tmp_tb;
        PyErr_Fetch(&tmp_type, &tmp_value, &tmp_tb);
        Py_INCREF(tb);
        PyErr_Restore(tmp_type, tmp_value, tb);
        Py_XDECREF(tmp_tb);
#else
        PyThreadState *tstate = __Pyx_PyThreadState_Current;
        PyObject* tmp_tb = tstate->curexc_traceback;
        if (tb != tmp_tb) {
            Py_INCREF(tb);
            tstate->curexc_traceback = tb;
            Py_XDECREF(tmp_tb);
        }
#endif
    }
bad:
    Py_XDECREF(owned_instance);
    return;
}
#endif

/* None */
static CYTHON_INLINE Py_ssize_t __Pyx_div_Py_ssize_t(Py_ssize_t a, Py_ssize_t b) {
    Py_ssize_t q = a / b;
    Py_ssize_t r = a - q*b;
    q -= ((r != 0) & ((r ^ b) < 0));
    return q;
}

/* GetAttr */
static CYTHON_INLINE PyObject *__Pyx_GetAttr(PyObject *o, PyObject *n) {
#if CYTHON_USE_TYPE_SLOTS
#if PY_MAJOR_VERSION >= 3
    if (likely(PyUnicode_Check(n)))
#else
    if (likely(PyString_Check(n)))
#endif
        return __Pyx_PyObject_GetAttrStr(o, n);
#endif
    return PyObject_GetAttr(o, n);
}

/* decode_c_string */
static CYTHON_INLINE PyObject* __Pyx_decode_c_string(
         const char* cstring, Py_ssize_t start, Py_ssize_t stop,
         const char* encoding, const char* errors,
         PyObject* (*decode_func)(const char *s, Py_ssize_t size, const char *errors)) {
    Py_ssize_t length;
    if (unlikely((start < 0) | (stop < 0))) {
        size_t slen = strlen(cstring);
        if (unlikely(slen > (size_t) PY_SSIZE_T_MAX)) {
            PyErr_SetString(PyExc_OverflowError,
                            "c-string too long to convert to Python");
            return NULL;
        }
        length = (Py_ssize_t) slen;
        if (start < 0) {
            start += length;
            if (start < 0)
                start = 0;
        }
        if (stop < 0)
            stop += length;
    }
    length = stop - start;
    if (unlikely(length <= 0))
        return PyUnicode_FromUnicode(NULL, 0);
    cstring += start;
    if (decode_func) {
        return decode_func(cstring, length, errors);
    } else {
        return PyUnicode_Decode(cstring, length, encoding, errors);
    }
}

/* PyErrExceptionMatches */
#if CYTHON_FAST_THREAD_STATE
static int __Pyx_PyErr_ExceptionMatchesTuple(PyObject *exc_type, PyObject *tuple) {
    Py_ssize_t i, n;
    n = PyTuple_GET_SIZE(tuple);
#if PY_MAJOR_VERSION >= 3
    for (i=0; i<n; i++) {
        if (exc_type == PyTuple_GET_ITEM(tuple, i)) return 1;
    }
#endif
    for (i=0; i<n; i++) {
        if (__Pyx_PyErr_GivenExceptionMatches(exc_type, PyTuple_GET_ITEM(tuple, i))) return 1;
    }
    return 0;
}
static CYTHON_INLINE int __Pyx_PyErr_ExceptionMatchesInState(PyThreadState* tstate, PyObject* err) {
    PyObject *exc_type = tstate->curexc_type;
    if (exc_type == err) return 1;
    if (unlikely(!exc_type)) return 0;
    if (unlikely(PyTuple_Check(err)))
        return __Pyx_PyErr_ExceptionMatchesTuple(exc_type, err);
    return __Pyx_PyErr_GivenExceptionMatches(exc_type, err);
}
#endif

/* GetAttr3 */
static PyObject *__Pyx_GetAttr3Default(PyObject *d) {
    __Pyx_PyThreadState_declare
    __Pyx_PyThreadState_assign
    if (unlikely(!__Pyx_PyErr_ExceptionMatches(PyExc_AttributeError)))
        return NULL;
    __Pyx_PyErr_Clear();
    Py_INCREF(d);
    return d;
}
static CYTHON_INLINE PyObject *__Pyx_GetAttr3(PyObject *o, PyObject *n, PyObject *d) {
    PyObject *r = __Pyx_GetAttr(o, n);
    return (likely(r)) ? r : __Pyx_GetAttr3Default(d);
}

/* RaiseNoneIterError */
static CYTHON_INLINE void __Pyx_RaiseNoneNotIterableError(void) {
    PyErr_SetString(PyExc_TypeError, "'NoneType' object is not iterable");
}

/* ExtTypeTest */
static CYTHON_INLINE int __Pyx_TypeTest(PyObject *obj, PyTypeObject *type) {
    if (unlikely(!type)) {
        PyErr_SetString(PyExc_SystemError, "Missing type object");
        return 0;
    }
    if (likely(__Pyx_TypeCheck(obj, type)))
        return 1;
    PyErr_Format(PyExc_TypeError, "Cannot convert %.200s to %.200s",
                 Py_TYPE(obj)->tp_name, type->tp_name);
    return 0;
}

/* GetTopmostException */
#if CYTHON_USE_EXC_INFO_STACK
static _PyErr_StackItem *
__Pyx_PyErr_GetTopmostException(PyThreadState *tstate)
{
    _PyErr_StackItem *exc_info = tstate->exc_info;
    while ((exc_info->exc_type == NULL || exc_info->exc_type == Py_None) &&
           exc_info->previous_item != NULL)
    {
        exc_info = exc_info->previous_item;
    }
    return exc_info;
}
#endif

/* SaveResetException */
#if CYTHON_FAST_THREAD_STATE
static CYTHON_INLINE void __Pyx__ExceptionSave(PyThreadState *tstate, PyObject **type, PyObject **value, PyObject **tb) {
    #if CYTHON_USE_EXC_INFO_STACK
    _PyErr_StackItem *exc_info = __Pyx_PyErr_GetTopmostException(tstate);
    *type = exc_info->exc_type;
    *value = exc_info->exc_value;
    *tb = exc_info->exc_traceback;
    #else
    *type = tstate->exc_type;
    *value = tstate->exc_value;
    *tb = tstate->exc_traceback;
    #endif
    Py_XINCREF(*type);
    Py_XINCREF(*value);
    Py_XINCREF(*tb);
}
static CYTHON_INLINE void __Pyx__ExceptionReset(PyThreadState *tstate, PyObject *type, PyObject *value, PyObject *tb) {
    PyObject *tmp_type, *tmp_value, *tmp_tb;
    #if CYTHON_USE_EXC_INFO_STACK
    _PyErr_StackItem *exc_info = tstate->exc_info;
    tmp_type = exc_info->exc_type;
    tmp_value = exc_info->exc_value;
    tmp_tb = exc_info->exc_traceback;
    exc_info->exc_type = type;
    exc_info->exc_value = value;
    exc_info->exc_traceback = tb;
    #else
    tmp_type = tstate->exc_type;
    tmp_value = tstate->exc_value;
    tmp_tb = tstate->exc_traceback;
    tstate->exc_type = type;
    tstate->exc_value = value;
    tstate->exc_traceback = tb;
    #endif
    Py_XDECREF(tmp_type);
    Py_XDECREF(tmp_value);
    Py_XDECREF(tmp_tb);
}
#endif

/* GetException */
#if CYTHON_FAST_THREAD_STATE
static int __Pyx__GetException(PyThreadState *tstate, PyObject **type, PyObject **value, PyObject **tb)
#else
static int __Pyx_GetException(PyObject **type, PyObject **value, PyObject **tb)
#endif
{
    PyObject *local_type, *local_value, *local_tb;
#if CYTHON_FAST_THREAD_STATE
    PyObject *tmp_type, *tmp_value, *tmp_tb;
    local_type = tstate->curexc_type;
    local_value = tstate->curexc_value;
    local_tb = tstate->curexc_traceback;
    tstate->curexc_type = 0;
    tstate->curexc_value = 0;
    tstate->curexc_traceback = 0;
#else
    PyErr_Fetch(&local_type, &local_value, &local_tb);
#endif
    PyErr_NormalizeException(&local_type, &local_value, &local_tb);
#if CYTHON_FAST_THREAD_STATE
    if (unlikely(tstate->curexc_type))
#else
    if (unlikely(PyErr_Occurred()))
#endif
        goto bad;
    #if PY_MAJOR_VERSION >= 3
    if (local_tb) {
        if (unlikely(PyException_SetTraceback(local_value, local_tb) < 0))
            goto bad;
    }
    #endif
    Py_XINCREF(local_tb);
    Py_XINCREF(local_type);
    Py_XINCREF(local_value);
    *type = local_type;
    *value = local_value;
    *tb = local_tb;
#if CYTHON_FAST_THREAD_STATE
    #if CYTHON_USE_EXC_INFO_STACK
    {
        _PyErr_StackItem *exc_info = tstate->exc_info;
        tmp_type = exc_info->exc_type;
        tmp_value = exc_info->exc_value;
        tmp_tb = exc_info->exc_traceback;
        exc_info->exc_type = local_type;
        exc_info->exc_value = local_value;
        exc_info->exc_traceback = local_tb;
    }
    #else
    tmp_type = tstate->exc_type;
    tmp_value = tstate->exc_value;
    tmp_tb = tstate->exc_traceback;
    tstate->exc_type = local_type;
    tstate->exc_value = local_value;
    tstate->exc_traceback = local_tb;
    #endif
    Py_XDECREF(tmp_type);
    Py_XDECREF(tmp_value);
    Py_XDECREF(tmp_tb);
#else
    PyErr_SetExcInfo(local_type, local_value, local_tb);
#endif
    return 0;
bad:
    *type = 0;
    *value = 0;
    *tb = 0;
    Py_XDECREF(local_type);
    Py_XDECREF(local_value);
    Py_XDECREF(local_tb);
    return -1;
}

/* SwapException */
#if CYTHON_FAST_THREAD_STATE
static CYTHON_INLINE void __Pyx__ExceptionSwap(PyThreadState *tstate, PyObject **type, PyObject **value, PyObject **tb) {
    PyObject *tmp_type, *tmp_value, *tmp_tb;
    #if CYTHON_USE_EXC_INFO_STACK
    _PyErr_StackItem *exc_info = tstate->exc_info;
    tmp_type = exc_info->exc_type;
    tmp_value = exc_info->exc_value;
    tmp_tb = exc_info->exc_traceback;
    exc_info->exc_type = *type;
    exc_info->exc_value = *value;
    exc_info->exc_traceback = *tb;
    #else
    tmp_type = tstate->exc_type;
    tmp_value = tstate->exc_value;
    tmp_tb = tstate->exc_traceback;
    tstate->exc_type = *type;
    tstate->exc_value = *value;
    tstate->exc_traceback = *tb;
    #endif
    *type = tmp_type;
    *value = tmp_value;
    *tb = tmp_tb;
}
#else
static CYTHON_INLINE void __Pyx_ExceptionSwap(PyObject **type, PyObject **value, PyObject **tb) {
    PyObject *tmp_type, *tmp_value, *tmp_tb;
    PyErr_GetExcInfo(&tmp_type, &tmp_value, &tmp_tb);
    PyErr_SetExcInfo(*type, *value, *tb);
    *type = tmp_type;
    *value = tmp_value;
    *tb = tmp_tb;
}
#endif

/* Import */
static PyObject *__Pyx_Import(PyObject *name, PyObject *from_list, int level) {
    PyObject *empty_list = 0;
    PyObject *module = 0;
    PyObject *global_dict = 0;
    PyObject *empty_dict = 0;
    PyObject *list;
    #if PY_MAJOR_VERSION < 3
    PyObject *py_import;
    py_import = __Pyx_PyObject_GetAttrStr(__pyx_b, __pyx_n_s_import);
    if (!py_import)
        goto bad;
    #endif
    if (from_list)
        list = from_list;
    else {
        empty_list = PyList_New(0);
        if (!empty_list)
            goto bad;
        list = empty_list;
    }
    global_dict = PyModule_GetDict(__pyx_m);
    if (!global_dict)
        goto bad;
    empty_dict = PyDict_New();
    if (!empty_dict)
        goto bad;
    {
        #if PY_MAJOR_VERSION >= 3
        if (level == -1) {
            if (strchr(__Pyx_MODULE_NAME, '.')) {
                module = PyImport_ImportModuleLevelObject(
                    name, global_dict, empty_dict, list, 1);
                if (!module) {
                    if (!PyErr_ExceptionMatches(PyExc_ImportError))
                        goto bad;
                    PyErr_Clear();
                }
            }
            level = 0;
        }
        #endif
        if (!module) {
            #if PY_MAJOR_VERSION < 3
            PyObject *py_level = PyInt_FromLong(level);
            if (!py_level)
                goto bad;
            module = PyObject_CallFunctionObjArgs(py_import,
                name, global_dict, empty_dict, list, py_level, (PyObject *)NULL);
            Py_DECREF(py_level);
            #else
            module = PyImport_ImportModuleLevelObject(
                name, global_dict, empty_dict, list, level);
            #endif
        }
    }
bad:
    #if PY_MAJOR_VERSION < 3
    Py_XDECREF(py_import);
    #endif
    Py_XDECREF(empty_list);
    Py_XDECREF(empty_dict);
    return module;
}

/* FastTypeChecks */
#if CYTHON_COMPILING_IN_CPYTHON
static int __Pyx_InBases(PyTypeObject *a, PyTypeObject *b) {
    while (a) {
        a = a->tp_base;
        if (a == b)
            return 1;
    }
    return b == &PyBaseObject_Type;
}
static CYTHON_INLINE int __Pyx_IsSubtype(PyTypeObject *a, PyTypeObject *b) {
    PyObject *mro;
    if (a == b) return 1;
    mro = a->tp_mro;
    if (likely(mro)) {
        Py_ssize_t i, n;
        n = PyTuple_GET_SIZE(mro);
        for (i = 0; i < n; i++) {
            if (PyTuple_GET_ITEM(mro, i) == (PyObject *)b)
                return 1;
        }
        return 0;
    }
    return __Pyx_InBases(a, b);
}
#if PY_MAJOR_VERSION == 2
static int __Pyx_inner_PyErr_GivenExceptionMatches2(PyObject *err, PyObject* exc_type1, PyObject* exc_type2) {
    PyObject *exception, *value, *tb;
    int res;
    __Pyx_PyThreadState_declare
    __Pyx_PyThreadState_assign
    __Pyx_ErrFetch(&exception, &value, &tb);
    res = exc_type1 ? PyObject_IsSubclass(err, exc_type1) : 0;
    if (unlikely(res == -1)) {
        PyErr_WriteUnraisable(err);
        res = 0;
    }
    if (!res) {
        res = PyObject_IsSubclass(err, exc_type2);
        if (unlikely(res == -1)) {
            PyErr_WriteUnraisable(err);
            res = 0;
        }
    }
    __Pyx_ErrRestore(exception, value, tb);
    return res;
}
#else
static CYTHON_INLINE int __Pyx_inner_PyErr_GivenExceptionMatches2(PyObject *err, PyObject* exc_type1, PyObject *exc_type2) {
    int res = exc_type1 ? __Pyx_IsSubtype((PyTypeObject*)err, (PyTypeObject*)exc_type1) : 0;
    if (!res) {
        res = __Pyx_IsSubtype((PyTypeObject*)err, (PyTypeObject*)exc_type2);
    }
    return res;
}
#endif
static int __Pyx_PyErr_GivenExceptionMatchesTuple(PyObject *exc_type, PyObject *tuple) {
    Py_ssize_t i, n;
    assert(PyExceptionClass_Check(exc_type));
    n = PyTuple_GET_SIZE(tuple);
#if PY_MAJOR_VERSION >= 3
    for (i=0; i<n; i++) {
        if (exc_type == PyTuple_GET_ITEM(tuple, i)) return 1;
    }
#endif
    for (i=0; i<n; i++) {
        PyObject *t = PyTuple_GET_ITEM(tuple, i);
        #if PY_MAJOR_VERSION < 3
        if (likely(exc_type == t)) return 1;
        #endif
        if (likely(PyExceptionClass_Check(t))) {
            if (__Pyx_inner_PyErr_GivenExceptionMatches2(exc_type, NULL, t)) return 1;
        } else {
        }
    }
    return 0;
}
static CYTHON_INLINE int __Pyx_PyErr_GivenExceptionMatches(PyObject *err, PyObject* exc_type) {
    if (likely(err == exc_type)) return 1;
    if (likely(PyExceptionClass_Check(err))) {
        if (likely(PyExceptionClass_Check(exc_type))) {
            return __Pyx_inner_PyErr_GivenExceptionMatches2(err, NULL, exc_type);
        } else if (likely(PyTuple_Check(exc_type))) {
            return __Pyx_PyErr_GivenExceptionMatchesTuple(err, exc_type);
        } else {
        }
    }
    return PyErr_GivenExceptionMatches(err, exc_type);
}
static CYTHON_INLINE int __Pyx_PyErr_GivenExceptionMatches2(PyObject *err, PyObject *exc_type1, PyObject *exc_type2) {
    assert(PyExceptionClass_Check(exc_type1));
    assert(PyExceptionClass_Check(exc_type2));
    if (likely(err == exc_type1 || err == exc_type2)) return 1;
    if (likely(PyExceptionClass_Check(err))) {
        return __Pyx_inner_PyErr_GivenExceptionMatches2(err, exc_type1, exc_type2);
    }
    return (PyErr_GivenExceptionMatches(err, exc_type1) || PyErr_GivenExceptionMatches(err, exc_type2));
}
#endif

/* None */
static CYTHON_INLINE long __Pyx_div_long(long a, long b) {
    long q = a / b;
    long r = a - q*b;
    q -= ((r != 0) & ((r ^ b) < 0));
    return q;
}

/* WriteUnraisableException */
static void __Pyx_WriteUnraisable(const char *name, CYTHON_UNUSED int clineno,
                                  CYTHON_UNUSED int lineno, CYTHON_UNUSED const char *filename,
                                  int full_traceback, CYTHON_UNUSED int nogil) {
    PyObject *old_exc, *old_val, *old_tb;
    PyObject *ctx;
    __Pyx_PyThreadState_declare
#ifdef WITH_THREAD
    PyGILState_STATE state;
    if (nogil)
        state = PyGILState_Ensure();
#ifdef _MSC_VER
    else state = (PyGILState_STATE)-1;
#endif
#endif
    __Pyx_PyThreadState_assign
    __Pyx_ErrFetch(&old_exc, &old_val, &old_tb);
    if (full_traceback) {
        Py_XINCREF(old_exc);
        Py_XINCREF(old_val);
        Py_XINCREF(old_tb);
        __Pyx_ErrRestore(old_exc, old_val, old_tb);
        PyErr_PrintEx(1);
    }
    #if PY_MAJOR_VERSION < 3
    ctx = PyString_FromString(name);
    #else
    ctx = PyUnicode_FromString(name);
    #endif
    __Pyx_ErrRestore(old_exc, old_val, old_tb);
    if (!ctx) {
        PyErr_WriteUnraisable(Py_None);
    } else {
        PyErr_WriteUnraisable(ctx);
        Py_DECREF(ctx);
    }
#ifdef WITH_THREAD
    if (nogil)
        PyGILState_Release(state);
#endif
}

/* ImportFrom */
static PyObject* __Pyx_ImportFrom(PyObject* module, PyObject* name) {
    PyObject* value = __Pyx_PyObject_GetAttrStr(module, name);
    if (unlikely(!value) && PyErr_ExceptionMatches(PyExc_AttributeError)) {
        PyErr_Format(PyExc_ImportError,
        #if PY_MAJOR_VERSION < 3
            "cannot import name %.230s", PyString_AS_STRING(name));
        #else
            "cannot import name %S", name);
        #endif
    }
    return value;
}

/* HasAttr */
static CYTHON_INLINE int __Pyx_HasAttr(PyObject *o, PyObject *n) {
    PyObject *r;
    if (unlikely(!__Pyx_PyBaseString_Check(n))) {
        PyErr_SetString(PyExc_TypeError,
                        "hasattr(): attribute name must be string");
        return -1;
    }
    r = __Pyx_GetAttr(o, n);
    if (unlikely(!r)) {
        PyErr_Clear();
        return 0;
    } else {
        Py_DECREF(r);
        return 1;
    }
}

/* PyObject_GenericGetAttrNoDict */
#if CYTHON_USE_TYPE_SLOTS && CYTHON_USE_PYTYPE_LOOKUP && PY_VERSION_HEX < 0x03070000
static PyObject *__Pyx_RaiseGenericGetAttributeError(PyTypeObject *tp, PyObject *attr_name) {
    PyErr_Format(PyExc_AttributeError,
#if PY_MAJOR_VERSION >= 3
                 "'%.50s' object has no attribute '%U'",
                 tp->tp_name, attr_name);
#else
                 "'%.50s' object has no attribute '%.400s'",
                 tp->tp_name, PyString_AS_STRING(attr_name));
#endif
    return NULL;
}
static CYTHON_INLINE PyObject* __Pyx_PyObject_GenericGetAttrNoDict(PyObject* obj, PyObject* attr_name) {
    PyObject *descr;
    PyTypeObject *tp = Py_TYPE(obj);
    if (unlikely(!PyString_Check(attr_name))) {
        return PyObject_GenericGetAttr(obj, attr_name);
    }
    assert(!tp->tp_dictoffset);
    descr = _PyType_Lookup(tp, attr_name);
    if (unlikely(!descr)) {
        return __Pyx_RaiseGenericGetAttributeError(tp, attr_name);
    }
    Py_INCREF(descr);
    #if PY_MAJOR_VERSION < 3
    if (likely(PyType_HasFeature(Py_TYPE(descr), Py_TPFLAGS_HAVE_CLASS)))
    #endif
    {
        descrgetfunc f = Py_TYPE(descr)->tp_descr_get;
        if (unlikely(f)) {
            PyObject *res = f(descr, obj, (PyObject *)tp);
            Py_DECREF(descr);
            return res;
        }
    }
    return descr;
}
#endif

/* PyObject_GenericGetAttr */
#if CYTHON_USE_TYPE_SLOTS && CYTHON_USE_PYTYPE_LOOKUP && PY_VERSION_HEX < 0x03070000
static PyObject* __Pyx_PyObject_GenericGetAttr(PyObject* obj, PyObject* attr_name) {
    if (unlikely(Py_TYPE(obj)->tp_dictoffset)) {
        return PyObject_GenericGetAttr(obj, attr_name);
    }
    return __Pyx_PyObject_GenericGetAttrNoDict(obj, attr_name);
}
#endif

/* SetVTable */
static int __Pyx_SetVtable(PyObject *dict, void *vtable) {
#if PY_VERSION_HEX >= 0x02070000
    PyObject *ob = PyCapsule_New(vtable, 0, 0);
#else
    PyObject *ob = PyCObject_FromVoidPtr(vtable, 0);
#endif
    if (!ob)
        goto bad;
    if (PyDict_SetItem(dict, __pyx_n_s_pyx_vtable, ob) < 0)
        goto bad;
    Py_DECREF(ob);
    return 0;
bad:
    Py_XDECREF(ob);
    return -1;
}

/* SetupReduce */
static int __Pyx_setup_reduce_is_named(PyObject* meth, PyObject* name) {
  int ret;
  PyObject *name_attr;
  name_attr = __Pyx_PyObject_GetAttrStr(meth, __pyx_n_s_name_2);
  if (likely(name_attr)) {
      ret = PyObject_RichCompareBool(name_attr, name, Py_EQ);
  } else {
      ret = -1;
  }
  if (unlikely(ret < 0)) {
      PyErr_Clear();
      ret = 0;
  }
  Py_XDECREF(name_attr);
  return ret;
}
static int __Pyx_setup_reduce(PyObject* type_obj) {
    int ret = 0;
    PyObject *object_reduce = NULL;
    PyObject *object_reduce_ex = NULL;
    PyObject *reduce = NULL;
    PyObject *reduce_ex = NULL;
    PyObject *reduce_cython = NULL;
    PyObject *setstate = NULL;
    PyObject *setstate_cython = NULL;
#if CYTHON_USE_PYTYPE_LOOKUP
    if (_PyType_Lookup((PyTypeObject*)type_obj, __pyx_n_s_getstate)) goto GOOD;
#else
    if (PyObject_HasAttr(type_obj, __pyx_n_s_getstate)) goto GOOD;
#endif
#if CYTHON_USE_PYTYPE_LOOKUP
    object_reduce_ex = _PyType_Lookup(&PyBaseObject_Type, __pyx_n_s_reduce_ex); if (!object_reduce_ex) goto BAD;
#else
    object_reduce_ex = __Pyx_PyObject_GetAttrStr((PyObject*)&PyBaseObject_Type, __pyx_n_s_reduce_ex); if (!object_reduce_ex) goto BAD;
#endif
    reduce_ex = __Pyx_PyObject_GetAttrStr(type_obj, __pyx_n_s_reduce_ex); if (unlikely(!reduce_ex)) goto BAD;
    if (reduce_ex == object_reduce_ex) {
#if CYTHON_USE_PYTYPE_LOOKUP
        object_reduce = _PyType_Lookup(&PyBaseObject_Type, __pyx_n_s_reduce); if (!object_reduce) goto BAD;
#else
        object_reduce = __Pyx_PyObject_GetAttrStr((PyObject*)&PyBaseObject_Type, __pyx_n_s_reduce); if (!object_reduce) goto BAD;
#endif
        reduce = __Pyx_PyObject_GetAttrStr(type_obj, __pyx_n_s_reduce); if (unlikely(!reduce)) goto BAD;
        if (reduce == object_reduce || __Pyx_setup_reduce_is_named(reduce, __pyx_n_s_reduce_cython)) {
            reduce_cython = __Pyx_PyObject_GetAttrStr(type_obj, __pyx_n_s_reduce_cython); if (unlikely(!reduce_cython)) goto BAD;
            ret = PyDict_SetItem(((PyTypeObject*)type_obj)->tp_dict, __pyx_n_s_reduce, reduce_cython); if (unlikely(ret < 0)) goto BAD;
            ret = PyDict_DelItem(((PyTypeObject*)type_obj)->tp_dict, __pyx_n_s_reduce_cython); if (unlikely(ret < 0)) goto BAD;
            setstate = __Pyx_PyObject_GetAttrStr(type_obj, __pyx_n_s_setstate);
            if (!setstate) PyErr_Clear();
            if (!setstate || __Pyx_setup_reduce_is_named(setstate, __pyx_n_s_setstate_cython)) {
                setstate_cython = __Pyx_PyObject_GetAttrStr(type_obj, __pyx_n_s_setstate_cython); if (unlikely(!setstate_cython)) goto BAD;
                ret = PyDict_SetItem(((PyTypeObject*)type_obj)->tp_dict, __pyx_n_s_setstate, setstate_cython); if (unlikely(ret < 0)) goto BAD;
                ret = PyDict_DelItem(((PyTypeObject*)type_obj)->tp_dict, __pyx_n_s_setstate_cython); if (unlikely(ret < 0)) goto BAD;
            }
            PyType_Modified((PyTypeObject*)type_obj);
        }
    }
    goto GOOD;
BAD:
    if (!PyErr_Occurred())
        PyErr_Format(PyExc_RuntimeError, "Unable to initialize pickling for %s", ((PyTypeObject*)type_obj)->tp_name);
    ret = -1;
GOOD:
#if !CYTHON_USE_PYTYPE_LOOKUP
    Py_XDECREF(object_reduce);
    Py_XDECREF(object_reduce_ex);
#endif
    Py_XDECREF(reduce);
    Py_XDECREF(reduce_ex);
    Py_XDECREF(reduce_cython);
    Py_XDECREF(setstate);
    Py_XDECREF(setstate_cython);
    return ret;
}

/* CLineInTraceback */
#ifndef CYTHON_CLINE_IN_TRACEBACK
static int __Pyx_CLineForTraceback(PyThreadState *tstate, int c_line) {
    PyObject *use_cline;
    PyObject *ptype, *pvalue, *ptraceback;
#if CYTHON_COMPILING_IN_CPYTHON
    PyObject **cython_runtime_dict;
#endif
    if (unlikely(!__pyx_cython_runtime)) {
        return c_line;
    }
    __Pyx_ErrFetchInState(tstate, &ptype, &pvalue, &ptraceback);
#if CYTHON_COMPILING_IN_CPYTHON
    cython_runtime_dict = _PyObject_GetDictPtr(__pyx_cython_runtime);
    if (likely(cython_runtime_dict)) {
        __PYX_PY_DICT_LOOKUP_IF_MODIFIED(
            use_cline, *cython_runtime_dict,
            __Pyx_PyDict_GetItemStr(*cython_runtime_dict, __pyx_n_s_cline_in_traceback))
    } else
#endif
    {
      PyObject *use_cline_obj = __Pyx_PyObject_GetAttrStr(__pyx_cython_runtime, __pyx_n_s_cline_in_traceback);
      if (use_cline_obj) {
        use_cline = PyObject_Not(use_cline_obj) ? Py_False : Py_True;
        Py_DECREF(use_cline_obj);
      } else {
        PyErr_Clear();
        use_cline = NULL;
      }
    }
    if (!use_cline) {
        c_line = 0;
        PyObject_SetAttr(__pyx_cython_runtime, __pyx_n_s_cline_in_traceback, Py_False);
    }
    else if (use_cline == Py_False || (use_cline != Py_True && PyObject_Not(use_cline) != 0)) {
        c_line = 0;
    }
    __Pyx_ErrRestoreInState(tstate, ptype, pvalue, ptraceback);
    return c_line;
}
#endif

/* CodeObjectCache */
static int __pyx_bisect_code_objects(__Pyx_CodeObjectCacheEntry* entries, int count, int code_line) {
    int start = 0, mid = 0, end = count - 1;
    if (end >= 0 && code_line > entries[end].code_line) {
        return count;
    }
    while (start < end) {
        mid = start + (end - start) / 2;
        if (code_line < entries[mid].code_line) {
            end = mid;
        } else if (code_line > entries[mid].code_line) {
             start = mid + 1;
        } else {
            return mid;
        }
    }
    if (code_line <= entries[mid].code_line) {
        return mid;
    } else {
        return mid + 1;
    }
}
static PyCodeObject *__pyx_find_code_object(int code_line) {
    PyCodeObject* code_object;
    int pos;
    if (unlikely(!code_line) || unlikely(!__pyx_code_cache.entries)) {
        return NULL;
    }
    pos = __pyx_bisect_code_objects(__pyx_code_cache.entries, __pyx_code_cache.count, code_line);
    if (unlikely(pos >= __pyx_code_cache.count) || unlikely(__pyx_code_cache.entries[pos].code_line != code_line)) {
        return NULL;
    }
    code_object = __pyx_code_cache.entries[pos].code_object;
    Py_INCREF(code_object);
    return code_object;
}
static void __pyx_insert_code_object(int code_line, PyCodeObject* code_object) {
    int pos, i;
    __Pyx_CodeObjectCacheEntry* entries = __pyx_code_cache.entries;
    if (unlikely(!code_line)) {
        return;
    }
    if (unlikely(!entries)) {
        entries = (__Pyx_CodeObjectCacheEntry*)PyMem_Malloc(64*sizeof(__Pyx_CodeObjectCacheEntry));
        if (likely(entries)) {
            __pyx_code_cache.entries = entries;
            __pyx_code_cache.max_count = 64;
            __pyx_code_cache.count = 1;
            entries[0].code_line = code_line;
            entries[0].code_object = code_object;
            Py_INCREF(code_object);
        }
        return;
    }
    pos = __pyx_bisect_code_objects(__pyx_code_cache.entries, __pyx_code_cache.count, code_line);
    if ((pos < __pyx_code_cache.count) && unlikely(__pyx_code_cache.entries[pos].code_line == code_line)) {
        PyCodeObject* tmp = entries[pos].code_object;
        entries[pos].code_object = code_object;
        Py_DECREF(tmp);
        return;
    }
    if (__pyx_code_cache.count == __pyx_code_cache.max_count) {
        int new_max = __pyx_code_cache.max_count + 64;
        entries = (__Pyx_CodeObjectCacheEntry*)PyMem_Realloc(
            __pyx_code_cache.entries, (size_t)new_max*sizeof(__Pyx_CodeObjectCacheEntry));
        if (unlikely(!entries)) {
            return;
        }
        __pyx_code_cache.entries = entries;
        __pyx_code_cache.max_count = new_max;
    }
    for (i=__pyx_code_cache.count; i>pos; i--) {
        entries[i] = entries[i-1];
    }
    entries[pos].code_line = code_line;
    entries[pos].code_object = code_object;
    __pyx_code_cache.count++;
    Py_INCREF(code_object);
}

/* AddTraceback */
#include "compile.h"
#include "frameobject.h"
#include "traceback.h"
static PyCodeObject* __Pyx_CreateCodeObjectForTraceback(
            const char *funcname, int c_line,
            int py_line, const char *filename) {
    PyCodeObject *py_code = 0;
    PyObject *py_srcfile = 0;
    PyObject *py_funcname = 0;
    #if PY_MAJOR_VERSION < 3
    py_srcfile = PyString_FromString(filename);
    #else
    py_srcfile = PyUnicode_FromString(filename);
    #endif
    if (!py_srcfile) goto bad;
    if (c_line) {
        #if PY_MAJOR_VERSION < 3
        py_funcname = PyString_FromFormat( "%s (%s:%d)", funcname, __pyx_cfilenm, c_line);
        #else
        py_funcname = PyUnicode_FromFormat( "%s (%s:%d)", funcname, __pyx_cfilenm, c_line);
        #endif
    }
    else {
        #if PY_MAJOR_VERSION < 3
        py_funcname = PyString_FromString(funcname);
        #else
        py_funcname = PyUnicode_FromString(funcname);
        #endif
    }
    if (!py_funcname) goto bad;
    py_code = __Pyx_PyCode_New(
        0,
        0,
        0,
        0,
        0,
        __pyx_empty_bytes, /*PyObject *code,*/
        __pyx_empty_tuple, /*PyObject *consts,*/
        __pyx_empty_tuple, /*PyObject *names,*/
        __pyx_empty_tuple, /*PyObject *varnames,*/
        __pyx_empty_tuple, /*PyObject *freevars,*/
        __pyx_empty_tuple, /*PyObject *cellvars,*/
        py_srcfile,   /*PyObject *filename,*/
        py_funcname,  /*PyObject *name,*/
        py_line,
        __pyx_empty_bytes  /*PyObject *lnotab*/
    );
    Py_DECREF(py_srcfile);
    Py_DECREF(py_funcname);
    return py_code;
bad:
    Py_XDECREF(py_srcfile);
    Py_XDECREF(py_funcname);
    return NULL;
}
static void __Pyx_AddTraceback(const char *funcname, int c_line,
                               int py_line, const char *filename) {
    PyCodeObject *py_code = 0;
    PyFrameObject *py_frame = 0;
    PyThreadState *tstate = __Pyx_PyThreadState_Current;
    if (c_line) {
        c_line = __Pyx_CLineForTraceback(tstate, c_line);
    }
    py_code = __pyx_find_code_object(c_line ? -c_line : py_line);
    if (!py_code) {
        py_code = __Pyx_CreateCodeObjectForTraceback(
            funcname, c_line, py_line, filename);
        if (!py_code) goto bad;
        __pyx_insert_code_object(c_line ? -c_line : py_line, py_code);
    }
    py_frame = PyFrame_New(
        tstate,            /*PyThreadState *tstate,*/
        py_code,           /*PyCodeObject *code,*/
        __pyx_d,    /*PyObject *globals,*/
        0                  /*PyObject *locals*/
    );
    if (!py_frame) goto bad;
    __Pyx_PyFrame_SetLineNumber(py_frame, py_line);
    PyTraceBack_Here(py_frame);
bad:
    Py_XDECREF(py_code);
    Py_XDECREF(py_frame);
}

#if PY_MAJOR_VERSION < 3
static int __Pyx_GetBuffer(PyObject *obj, Py_buffer *view, int flags) {
    if (PyObject_CheckBuffer(obj)) return PyObject_GetBuffer(obj, view, flags);
        if (__Pyx_TypeCheck(obj, __pyx_array_type)) return __pyx_array_getbuffer(obj, view, flags);
        if (__Pyx_TypeCheck(obj, __pyx_memoryview_type)) return __pyx_memoryview_getbuffer(obj, view, flags);
    PyErr_Format(PyExc_TypeError, "'%.200s' does not have the buffer interface", Py_TYPE(obj)->tp_name);
    return -1;
}
static void __Pyx_ReleaseBuffer(Py_buffer *view) {
    PyObject *obj = view->obj;
    if (!obj) return;
    if (PyObject_CheckBuffer(obj)) {
        PyBuffer_Release(view);
        return;
    }
    if ((0)) {}
    view->obj = NULL;
    Py_DECREF(obj);
}
#endif


/* MemviewSliceIsContig */
static int
__pyx_memviewslice_is_contig(const __Pyx_memviewslice mvs, char order, int ndim)
{
    int i, index, step, start;
    Py_ssize_t itemsize = mvs.memview->view.itemsize;
    if (order == 'F') {
        step = 1;
        start = 0;
    } else {
        step = -1;
        start = ndim - 1;
    }
    for (i = 0; i < ndim; i++) {
        index = start + step * i;
        if (mvs.suboffsets[index] >= 0 || mvs.strides[index] != itemsize)
            return 0;
        itemsize *= mvs.shape[index];
    }
    return 1;
}

/* OverlappingSlices */
static void
__pyx_get_array_memory_extents(__Pyx_memviewslice *slice,
                               void **out_start, void **out_end,
                               int ndim, size_t itemsize)
{
    char *start, *end;
    int i;
    start = end = slice->data;
    for (i = 0; i < ndim; i++) {
        Py_ssize_t stride = slice->strides[i];
        Py_ssize_t extent = slice->shape[i];
        if (extent == 0) {
            *out_start = *out_end = start;
            return;
        } else {
            if (stride > 0)
                end += stride * (extent - 1);
            else
                start += stride * (extent - 1);
        }
    }
    *out_start = start;
    *out_end = end + itemsize;
}
static int
__pyx_slices_overlap(__Pyx_memviewslice *slice1,
                     __Pyx_memviewslice *slice2,
                     int ndim, size_t itemsize)
{
    void *start1, *end1, *start2, *end2;
    __pyx_get_array_memory_extents(slice1, &start1, &end1, ndim, itemsize);
    __pyx_get_array_memory_extents(slice2, &start2, &end2, ndim, itemsize);
    return (start1 < end2) && (start2 < end1);
}

/* Capsule */
static CYTHON_INLINE PyObject *
__pyx_capsule_create(void *p, CYTHON_UNUSED const char *sig)
{
    PyObject *cobj;
#if PY_VERSION_HEX >= 0x02070000
    cobj = PyCapsule_New(p, sig, NULL);
#else
    cobj = PyCObject_FromVoidPtr(p, NULL);
#endif
    return cobj;
}

/* CIntToPy */
static CYTHON_INLINE PyObject* __Pyx_PyInt_From_long(long value) {
    const long neg_one = (long) ((long) 0 - (long) 1), const_zero = (long) 0;
    const int is_unsigned = neg_one > const_zero;
    if (is_unsigned) {
        if (sizeof(long) < sizeof(long)) {
            return PyInt_FromLong((long) value);
        } else if (sizeof(long) <= sizeof(unsigned long)) {
            return PyLong_FromUnsignedLong((unsigned long) value);
#ifdef HAVE_LONG_LONG
        } else if (sizeof(long) <= sizeof(unsigned PY_LONG_LONG)) {
            return PyLong_FromUnsignedLongLong((unsigned PY_LONG_LONG) value);
#endif
        }
    } else {
        if (sizeof(long) <= sizeof(long)) {
            return PyInt_FromLong((long) value);
#ifdef HAVE_LONG_LONG
        } else if (sizeof(long) <= sizeof(PY_LONG_LONG)) {
            return PyLong_FromLongLong((PY_LONG_LONG) value);
#endif
        }
    }
    {
        int one = 1; int little = (int)*(unsigned char *)&one;
        unsigned char *bytes = (unsigned char *)&value;
        return _PyLong_FromByteArray(bytes, sizeof(long),
                                     little, !is_unsigned);
    }
}

/* CIntToPy */
static CYTHON_INLINE PyObject* __Pyx_PyInt_From_int(int value) {
    const int neg_one = (int) ((int) 0 - (int) 1), const_zero = (int) 0;
    const int is_unsigned = neg_one > const_zero;
    if (is_unsigned) {
        if (sizeof(int) < sizeof(long)) {
            return PyInt_FromLong((long) value);
        } else if (sizeof(int) <= sizeof(unsigned long)) {
            return PyLong_FromUnsignedLong((unsigned long) value);
#ifdef HAVE_LONG_LONG
        } else if (sizeof(int) <= sizeof(unsigned PY_LONG_LONG)) {
            return PyLong_FromUnsignedLongLong((unsigned PY_LONG_LONG) value);
#endif
        }
    } else {
        if (sizeof(int) <= sizeof(long)) {
            return PyInt_FromLong((long) value);
#ifdef HAVE_LONG_LONG
        } else if (sizeof(int) <= sizeof(PY_LONG_LONG)) {
            return PyLong_FromLongLong((PY_LONG_LONG) value);
#endif
        }
    }
    {
        int one = 1; int little = (int)*(unsigned char *)&one;
        unsigned char *bytes = (unsigned char *)&value;
        return _PyLong_FromByteArray(bytes, sizeof(int),
                                     little, !is_unsigned);
    }
}

/* CIntFromPyVerify */
#define __PYX_VERIFY_RETURN_INT(target_type, func_type, func_value)\
    __PYX__VERIFY_RETURN_INT(target_type, func_type, func_value, 0)
#define __PYX_VERIFY_RETURN_INT_EXC(target_type, func_type, func_value)\
    __PYX__VERIFY_RETURN_INT(target_type, func_type, func_value, 1)
#define __PYX__VERIFY_RETURN_INT(target_type, func_type, func_value, exc)\
    {\
        func_type value = func_value;\
        if (sizeof(target_type) < sizeof(func_type)) {\
            if (unlikely(value != (func_type) (target_type) value)) {\
                func_type zero = 0;\
                if (exc && unlikely(value == (func_type)-1 && PyErr_Occurred()))\
                    return (target_type) -1;\
                if (is_unsigned && unlikely(value < zero))\
                    goto raise_neg_overflow;\
                else\
                    goto raise_overflow;\
            }\
        }\
        return (target_type) value;\
    }

/* MemviewDtypeToObject */
static CYTHON_INLINE PyObject *__pyx_memview_get_double(const char *itemp) {
    return (PyObject *) PyFloat_FromDouble(*(double *) itemp);
}
static CYTHON_INLINE int __pyx_memview_set_double(const char *itemp, PyObject *obj) {
    double value = __pyx_PyFloat_AsDouble(obj);
    if ((value == (double)-1) && PyErr_Occurred())
        return 0;
    *(double *) itemp = value;
    return 1;
}

/* MemviewSliceCopyTemplate */
static __Pyx_memviewslice
__pyx_memoryview_copy_new_contig(const __Pyx_memviewslice *from_mvs,
                                 const char *mode, int ndim,
                                 size_t sizeof_dtype, int contig_flag,
                                 int dtype_is_object)
{
    __Pyx_RefNannyDeclarations
    int i;
    __Pyx_memviewslice new_mvs = { 0, 0, { 0 }, { 0 }, { 0 } };
    struct __pyx_memoryview_obj *from_memview = from_mvs->memview;
    Py_buffer *buf = &from_memview->view;
    PyObject *shape_tuple = NULL;
    PyObject *temp_int = NULL;
    struct __pyx_array_obj *array_obj = NULL;
    struct __pyx_memoryview_obj *memview_obj = NULL;
    __Pyx_RefNannySetupContext("__pyx_memoryview_copy_new_contig", 0);
    for (i = 0; i < ndim; i++) {
        if (from_mvs->suboffsets[i] >= 0) {
            PyErr_Format(PyExc_ValueError, "Cannot copy memoryview slice with "
                                           "indirect dimensions (axis %d)", i);
            goto fail;
        }
    }
    shape_tuple = PyTuple_New(ndim);
    if (unlikely(!shape_tuple)) {
        goto fail;
    }
    __Pyx_GOTREF(shape_tuple);
    for(i = 0; i < ndim; i++) {
        temp_int = PyInt_FromSsize_t(from_mvs->shape[i]);
        if(unlikely(!temp_int)) {
            goto fail;
        } else {
            PyTuple_SET_ITEM(shape_tuple, i, temp_int);
            temp_int = NULL;
        }
    }
    array_obj = __pyx_array_new(shape_tuple, sizeof_dtype, buf->format, (char *) mode, NULL);
    if (unlikely(!array_obj)) {
        goto fail;
    }
    __Pyx_GOTREF(array_obj);
    memview_obj = (struct __pyx_memoryview_obj *) __pyx_memoryview_new(
                                    (PyObject *) array_obj, contig_flag,
                                    dtype_is_object,
                                    from_mvs->memview->typeinfo);
    if (unlikely(!memview_obj))
        goto fail;
    if (unlikely(__Pyx_init_memviewslice(memview_obj, ndim, &new_mvs, 1) < 0))
        goto fail;
    if (unlikely(__pyx_memoryview_copy_contents(*from_mvs, new_mvs, ndim, ndim,
                                                dtype_is_object) < 0))
        goto fail;
    goto no_fail;
fail:
    __Pyx_XDECREF(new_mvs.memview);
    new_mvs.memview = NULL;
    new_mvs.data = NULL;
no_fail:
    __Pyx_XDECREF(shape_tuple);
    __Pyx_XDECREF(temp_int);
    __Pyx_XDECREF(array_obj);
    __Pyx_RefNannyFinishContext();
    return new_mvs;
}

/* CIntFromPy */
static CYTHON_INLINE int __Pyx_PyInt_As_int(PyObject *x) {
    const int neg_one = (int) ((int) 0 - (int) 1), const_zero = (int) 0;
    const int is_unsigned = neg_one > const_zero;
#if PY_MAJOR_VERSION < 3
    if (likely(PyInt_Check(x))) {
        if (sizeof(int) < sizeof(long)) {
            __PYX_VERIFY_RETURN_INT(int, long, PyInt_AS_LONG(x))
        } else {
            long val = PyInt_AS_LONG(x);
            if (is_unsigned && unlikely(val < 0)) {
                goto raise_neg_overflow;
            }
            return (int) val;
        }
    } else
#endif
    if (likely(PyLong_Check(x))) {
        if (is_unsigned) {
#if CYTHON_USE_PYLONG_INTERNALS
            const digit* digits = ((PyLongObject*)x)->ob_digit;
            switch (Py_SIZE(x)) {
                case  0: return (int) 0;
                case  1: __PYX_VERIFY_RETURN_INT(int, digit, digits[0])
                case 2:
                    if (8 * sizeof(int) > 1 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 2 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(int, unsigned long, (((((unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(int) >= 2 * PyLong_SHIFT) {
                            return (int) (((((int)digits[1]) << PyLong_SHIFT) | (int)digits[0]));
                        }
                    }
                    break;
                case 3:
                    if (8 * sizeof(int) > 2 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 3 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(int, unsigned long, (((((((unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(int) >= 3 * PyLong_SHIFT) {
                            return (int) (((((((int)digits[2]) << PyLong_SHIFT) | (int)digits[1]) << PyLong_SHIFT) | (int)digits[0]));
                        }
                    }
                    break;
                case 4:
                    if (8 * sizeof(int) > 3 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 4 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(int, unsigned long, (((((((((unsigned long)digits[3]) << PyLong_SHIFT) | (unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(int) >= 4 * PyLong_SHIFT) {
                            return (int) (((((((((int)digits[3]) << PyLong_SHIFT) | (int)digits[2]) << PyLong_SHIFT) | (int)digits[1]) << PyLong_SHIFT) | (int)digits[0]));
                        }
                    }
                    break;
            }
#endif
#if CYTHON_COMPILING_IN_CPYTHON
            if (unlikely(Py_SIZE(x) < 0)) {
                goto raise_neg_overflow;
            }
#else
            {
                int result = PyObject_RichCompareBool(x, Py_False, Py_LT);
                if (unlikely(result < 0))
                    return (int) -1;
                if (unlikely(result == 1))
                    goto raise_neg_overflow;
            }
#endif
            if (sizeof(int) <= sizeof(unsigned long)) {
                __PYX_VERIFY_RETURN_INT_EXC(int, unsigned long, PyLong_AsUnsignedLong(x))
#ifdef HAVE_LONG_LONG
            } else if (sizeof(int) <= sizeof(unsigned PY_LONG_LONG)) {
                __PYX_VERIFY_RETURN_INT_EXC(int, unsigned PY_LONG_LONG, PyLong_AsUnsignedLongLong(x))
#endif
            }
        } else {
#if CYTHON_USE_PYLONG_INTERNALS
            const digit* digits = ((PyLongObject*)x)->ob_digit;
            switch (Py_SIZE(x)) {
                case  0: return (int) 0;
                case -1: __PYX_VERIFY_RETURN_INT(int, sdigit, (sdigit) (-(sdigit)digits[0]))
                case  1: __PYX_VERIFY_RETURN_INT(int,  digit, +digits[0])
                case -2:
                    if (8 * sizeof(int) - 1 > 1 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 2 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(int, long, -(long) (((((unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(int) - 1 > 2 * PyLong_SHIFT) {
                            return (int) (((int)-1)*(((((int)digits[1]) << PyLong_SHIFT) | (int)digits[0])));
                        }
                    }
                    break;
                case 2:
                    if (8 * sizeof(int) > 1 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 2 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(int, unsigned long, (((((unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(int) - 1 > 2 * PyLong_SHIFT) {
                            return (int) ((((((int)digits[1]) << PyLong_SHIFT) | (int)digits[0])));
                        }
                    }
                    break;
                case -3:
                    if (8 * sizeof(int) - 1 > 2 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 3 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(int, long, -(long) (((((((unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(int) - 1 > 3 * PyLong_SHIFT) {
                            return (int) (((int)-1)*(((((((int)digits[2]) << PyLong_SHIFT) | (int)digits[1]) << PyLong_SHIFT) | (int)digits[0])));
                        }
                    }
                    break;
                case 3:
                    if (8 * sizeof(int) > 2 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 3 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(int, unsigned long, (((((((unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(int) - 1 > 3 * PyLong_SHIFT) {
                            return (int) ((((((((int)digits[2]) << PyLong_SHIFT) | (int)digits[1]) << PyLong_SHIFT) | (int)digits[0])));
                        }
                    }
                    break;
                case -4:
                    if (8 * sizeof(int) - 1 > 3 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 4 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(int, long, -(long) (((((((((unsigned long)digits[3]) << PyLong_SHIFT) | (unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(int) - 1 > 4 * PyLong_SHIFT) {
                            return (int) (((int)-1)*(((((((((int)digits[3]) << PyLong_SHIFT) | (int)digits[2]) << PyLong_SHIFT) | (int)digits[1]) << PyLong_SHIFT) | (int)digits[0])));
                        }
                    }
                    break;
                case 4:
                    if (8 * sizeof(int) > 3 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 4 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(int, unsigned long, (((((((((unsigned long)digits[3]) << PyLong_SHIFT) | (unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(int) - 1 > 4 * PyLong_SHIFT) {
                            return (int) ((((((((((int)digits[3]) << PyLong_SHIFT) | (int)digits[2]) << PyLong_SHIFT) | (int)digits[1]) << PyLong_SHIFT) | (int)digits[0])));
                        }
                    }
                    break;
            }
#endif
            if (sizeof(int) <= sizeof(long)) {
                __PYX_VERIFY_RETURN_INT_EXC(int, long, PyLong_AsLong(x))
#ifdef HAVE_LONG_LONG
            } else if (sizeof(int) <= sizeof(PY_LONG_LONG)) {
                __PYX_VERIFY_RETURN_INT_EXC(int, PY_LONG_LONG, PyLong_AsLongLong(x))
#endif
            }
        }
        {
#if CYTHON_COMPILING_IN_PYPY && !defined(_PyLong_AsByteArray)
            PyErr_SetString(PyExc_RuntimeError,
                            "_PyLong_AsByteArray() not available in PyPy, cannot convert large numbers");
#else
            int val;
            PyObject *v = __Pyx_PyNumber_IntOrLong(x);
 #if PY_MAJOR_VERSION < 3
            if (likely(v) && !PyLong_Check(v)) {
                PyObject *tmp = v;
                v = PyNumber_Long(tmp);
                Py_DECREF(tmp);
            }
 #endif
            if (likely(v)) {
                int one = 1; int is_little = (int)*(unsigned char *)&one;
                unsigned char *bytes = (unsigned char *)&val;
                int ret = _PyLong_AsByteArray((PyLongObject *)v,
                                              bytes, sizeof(val),
                                              is_little, !is_unsigned);
                Py_DECREF(v);
                if (likely(!ret))
                    return val;
            }
#endif
            return (int) -1;
        }
    } else {
        int val;
        PyObject *tmp = __Pyx_PyNumber_IntOrLong(x);
        if (!tmp) return (int) -1;
        val = __Pyx_PyInt_As_int(tmp);
        Py_DECREF(tmp);
        return val;
    }
raise_overflow:
    PyErr_SetString(PyExc_OverflowError,
        "value too large to convert to int");
    return (int) -1;
raise_neg_overflow:
    PyErr_SetString(PyExc_OverflowError,
        "can't convert negative value to int");
    return (int) -1;
}

/* CIntFromPy */
static CYTHON_INLINE long __Pyx_PyInt_As_long(PyObject *x) {
    const long neg_one = (long) ((long) 0 - (long) 1), const_zero = (long) 0;
    const int is_unsigned = neg_one > const_zero;
#if PY_MAJOR_VERSION < 3
    if (likely(PyInt_Check(x))) {
        if (sizeof(long) < sizeof(long)) {
            __PYX_VERIFY_RETURN_INT(long, long, PyInt_AS_LONG(x))
        } else {
            long val = PyInt_AS_LONG(x);
            if (is_unsigned && unlikely(val < 0)) {
                goto raise_neg_overflow;
            }
            return (long) val;
        }
    } else
#endif
    if (likely(PyLong_Check(x))) {
        if (is_unsigned) {
#if CYTHON_USE_PYLONG_INTERNALS
            const digit* digits = ((PyLongObject*)x)->ob_digit;
            switch (Py_SIZE(x)) {
                case  0: return (long) 0;
                case  1: __PYX_VERIFY_RETURN_INT(long, digit, digits[0])
                case 2:
                    if (8 * sizeof(long) > 1 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 2 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(long, unsigned long, (((((unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(long) >= 2 * PyLong_SHIFT) {
                            return (long) (((((long)digits[1]) << PyLong_SHIFT) | (long)digits[0]));
                        }
                    }
                    break;
                case 3:
                    if (8 * sizeof(long) > 2 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 3 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(long, unsigned long, (((((((unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(long) >= 3 * PyLong_SHIFT) {
                            return (long) (((((((long)digits[2]) << PyLong_SHIFT) | (long)digits[1]) << PyLong_SHIFT) | (long)digits[0]));
                        }
                    }
                    break;
                case 4:
                    if (8 * sizeof(long) > 3 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 4 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(long, unsigned long, (((((((((unsigned long)digits[3]) << PyLong_SHIFT) | (unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(long) >= 4 * PyLong_SHIFT) {
                            return (long) (((((((((long)digits[3]) << PyLong_SHIFT) | (long)digits[2]) << PyLong_SHIFT) | (long)digits[1]) << PyLong_SHIFT) | (long)digits[0]));
                        }
                    }
                    break;
            }
#endif
#if CYTHON_COMPILING_IN_CPYTHON
            if (unlikely(Py_SIZE(x) < 0)) {
                goto raise_neg_overflow;
            }
#else
            {
                int result = PyObject_RichCompareBool(x, Py_False, Py_LT);
                if (unlikely(result < 0))
                    return (long) -1;
                if (unlikely(result == 1))
                    goto raise_neg_overflow;
            }
#endif
            if (sizeof(long) <= sizeof(unsigned long)) {
                __PYX_VERIFY_RETURN_INT_EXC(long, unsigned long, PyLong_AsUnsignedLong(x))
#ifdef HAVE_LONG_LONG
            } else if (sizeof(long) <= sizeof(unsigned PY_LONG_LONG)) {
                __PYX_VERIFY_RETURN_INT_EXC(long, unsigned PY_LONG_LONG, PyLong_AsUnsignedLongLong(x))
#endif
            }
        } else {
#if CYTHON_USE_PYLONG_INTERNALS
            const digit* digits = ((PyLongObject*)x)->ob_digit;
            switch (Py_SIZE(x)) {
                case  0: return (long) 0;
                case -1: __PYX_VERIFY_RETURN_INT(long, sdigit, (sdigit) (-(sdigit)digits[0]))
                case  1: __PYX_VERIFY_RETURN_INT(long,  digit, +digits[0])
                case -2:
                    if (8 * sizeof(long) - 1 > 1 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 2 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(long, long, -(long) (((((unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(long) - 1 > 2 * PyLong_SHIFT) {
                            return (long) (((long)-1)*(((((long)digits[1]) << PyLong_SHIFT) | (long)digits[0])));
                        }
                    }
                    break;
                case 2:
                    if (8 * sizeof(long) > 1 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 2 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(long, unsigned long, (((((unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(long) - 1 > 2 * PyLong_SHIFT) {
                            return (long) ((((((long)digits[1]) << PyLong_SHIFT) | (long)digits[0])));
                        }
                    }
                    break;
                case -3:
                    if (8 * sizeof(long) - 1 > 2 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 3 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(long, long, -(long) (((((((unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(long) - 1 > 3 * PyLong_SHIFT) {
                            return (long) (((long)-1)*(((((((long)digits[2]) << PyLong_SHIFT) | (long)digits[1]) << PyLong_SHIFT) | (long)digits[0])));
                        }
                    }
                    break;
                case 3:
                    if (8 * sizeof(long) > 2 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 3 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(long, unsigned long, (((((((unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(long) - 1 > 3 * PyLong_SHIFT) {
                            return (long) ((((((((long)digits[2]) << PyLong_SHIFT) | (long)digits[1]) << PyLong_SHIFT) | (long)digits[0])));
                        }
                    }
                    break;
                case -4:
                    if (8 * sizeof(long) - 1 > 3 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 4 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(long, long, -(long) (((((((((unsigned long)digits[3]) << PyLong_SHIFT) | (unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(long) - 1 > 4 * PyLong_SHIFT) {
                            return (long) (((long)-1)*(((((((((long)digits[3]) << PyLong_SHIFT) | (long)digits[2]) << PyLong_SHIFT) | (long)digits[1]) << PyLong_SHIFT) | (long)digits[0])));
                        }
                    }
                    break;
                case 4:
                    if (8 * sizeof(long) > 3 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 4 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(long, unsigned long, (((((((((unsigned long)digits[3]) << PyLong_SHIFT) | (unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(long) - 1 > 4 * PyLong_SHIFT) {
                            return (long) ((((((((((long)digits[3]) << PyLong_SHIFT) | (long)digits[2]) << PyLong_SHIFT) | (long)digits[1]) << PyLong_SHIFT) | (long)digits[0])));
                        }
                    }
                    break;
            }
#endif
            if (sizeof(long) <= sizeof(long)) {
                __PYX_VERIFY_RETURN_INT_EXC(long, long, PyLong_AsLong(x))
#ifdef HAVE_LONG_LONG
            } else if (sizeof(long) <= sizeof(PY_LONG_LONG)) {
                __PYX_VERIFY_RETURN_INT_EXC(long, PY_LONG_LONG, PyLong_AsLongLong(x))
#endif
            }
        }
        {
#if CYTHON_COMPILING_IN_PYPY && !defined(_PyLong_AsByteArray)
            PyErr_SetString(PyExc_RuntimeError,
                            "_PyLong_AsByteArray() not available in PyPy, cannot convert large numbers");
#else
            long val;
            PyObject *v = __Pyx_PyNumber_IntOrLong(x);
 #if PY_MAJOR_VERSION < 3
            if (likely(v) && !PyLong_Check(v)) {
                PyObject *tmp = v;
                v = PyNumber_Long(tmp);
                Py_DECREF(tmp);
            }
 #endif
            if (likely(v)) {
                int one = 1; int is_little = (int)*(unsigned char *)&one;
                unsigned char *bytes = (unsigned char *)&val;
                int ret = _PyLong_AsByteArray((PyLongObject *)v,
                                              bytes, sizeof(val),
                                              is_little, !is_unsigned);
                Py_DECREF(v);
                if (likely(!ret))
                    return val;
            }
#endif
            return (long) -1;
        }
    } else {
        long val;
        PyObject *tmp = __Pyx_PyNumber_IntOrLong(x);
        if (!tmp) return (long) -1;
        val = __Pyx_PyInt_As_long(tmp);
        Py_DECREF(tmp);
        return val;
    }
raise_overflow:
    PyErr_SetString(PyExc_OverflowError,
        "value too large to convert to long");
    return (long) -1;
raise_neg_overflow:
    PyErr_SetString(PyExc_OverflowError,
        "can't convert negative value to long");
    return (long) -1;
}

/* CIntFromPy */
static CYTHON_INLINE char __Pyx_PyInt_As_char(PyObject *x) {
    const char neg_one = (char) ((char) 0 - (char) 1), const_zero = (char) 0;
    const int is_unsigned = neg_one > const_zero;
#if PY_MAJOR_VERSION < 3
    if (likely(PyInt_Check(x))) {
        if (sizeof(char) < sizeof(long)) {
            __PYX_VERIFY_RETURN_INT(char, long, PyInt_AS_LONG(x))
        } else {
            long val = PyInt_AS_LONG(x);
            if (is_unsigned && unlikely(val < 0)) {
                goto raise_neg_overflow;
            }
            return (char) val;
        }
    } else
#endif
    if (likely(PyLong_Check(x))) {
        if (is_unsigned) {
#if CYTHON_USE_PYLONG_INTERNALS
            const digit* digits = ((PyLongObject*)x)->ob_digit;
            switch (Py_SIZE(x)) {
                case  0: return (char) 0;
                case  1: __PYX_VERIFY_RETURN_INT(char, digit, digits[0])
                case 2:
                    if (8 * sizeof(char) > 1 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 2 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(char, unsigned long, (((((unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(char) >= 2 * PyLong_SHIFT) {
                            return (char) (((((char)digits[1]) << PyLong_SHIFT) | (char)digits[0]));
                        }
                    }
                    break;
                case 3:
                    if (8 * sizeof(char) > 2 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 3 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(char, unsigned long, (((((((unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(char) >= 3 * PyLong_SHIFT) {
                            return (char) (((((((char)digits[2]) << PyLong_SHIFT) | (char)digits[1]) << PyLong_SHIFT) | (char)digits[0]));
                        }
                    }
                    break;
                case 4:
                    if (8 * sizeof(char) > 3 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 4 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(char, unsigned long, (((((((((unsigned long)digits[3]) << PyLong_SHIFT) | (unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(char) >= 4 * PyLong_SHIFT) {
                            return (char) (((((((((char)digits[3]) << PyLong_SHIFT) | (char)digits[2]) << PyLong_SHIFT) | (char)digits[1]) << PyLong_SHIFT) | (char)digits[0]));
                        }
                    }
                    break;
            }
#endif
#if CYTHON_COMPILING_IN_CPYTHON
            if (unlikely(Py_SIZE(x) < 0)) {
                goto raise_neg_overflow;
            }
#else
            {
                int result = PyObject_RichCompareBool(x, Py_False, Py_LT);
                if (unlikely(result < 0))
                    return (char) -1;
                if (unlikely(result == 1))
                    goto raise_neg_overflow;
            }
#endif
            if (sizeof(char) <= sizeof(unsigned long)) {
                __PYX_VERIFY_RETURN_INT_EXC(char, unsigned long, PyLong_AsUnsignedLong(x))
#ifdef HAVE_LONG_LONG
            } else if (sizeof(char) <= sizeof(unsigned PY_LONG_LONG)) {
                __PYX_VERIFY_RETURN_INT_EXC(char, unsigned PY_LONG_LONG, PyLong_AsUnsignedLongLong(x))
#endif
            }
        } else {
#if CYTHON_USE_PYLONG_INTERNALS
            const digit* digits = ((PyLongObject*)x)->ob_digit;
            switch (Py_SIZE(x)) {
                case  0: return (char) 0;
                case -1: __PYX_VERIFY_RETURN_INT(char, sdigit, (sdigit) (-(sdigit)digits[0]))
                case  1: __PYX_VERIFY_RETURN_INT(char,  digit, +digits[0])
                case -2:
                    if (8 * sizeof(char) - 1 > 1 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 2 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(char, long, -(long) (((((unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(char) - 1 > 2 * PyLong_SHIFT) {
                            return (char) (((char)-1)*(((((char)digits[1]) << PyLong_SHIFT) | (char)digits[0])));
                        }
                    }
                    break;
                case 2:
                    if (8 * sizeof(char) > 1 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 2 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(char, unsigned long, (((((unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(char) - 1 > 2 * PyLong_SHIFT) {
                            return (char) ((((((char)digits[1]) << PyLong_SHIFT) | (char)digits[0])));
                        }
                    }
                    break;
                case -3:
                    if (8 * sizeof(char) - 1 > 2 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 3 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(char, long, -(long) (((((((unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(char) - 1 > 3 * PyLong_SHIFT) {
                            return (char) (((char)-1)*(((((((char)digits[2]) << PyLong_SHIFT) | (char)digits[1]) << PyLong_SHIFT) | (char)digits[0])));
                        }
                    }
                    break;
                case 3:
                    if (8 * sizeof(char) > 2 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 3 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(char, unsigned long, (((((((unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(char) - 1 > 3 * PyLong_SHIFT) {
                            return (char) ((((((((char)digits[2]) << PyLong_SHIFT) | (char)digits[1]) << PyLong_SHIFT) | (char)digits[0])));
                        }
                    }
                    break;
                case -4:
                    if (8 * sizeof(char) - 1 > 3 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 4 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(char, long, -(long) (((((((((unsigned long)digits[3]) << PyLong_SHIFT) | (unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(char) - 1 > 4 * PyLong_SHIFT) {
                            return (char) (((char)-1)*(((((((((char)digits[3]) << PyLong_SHIFT) | (char)digits[2]) << PyLong_SHIFT) | (char)digits[1]) << PyLong_SHIFT) | (char)digits[0])));
                        }
                    }
                    break;
                case 4:
                    if (8 * sizeof(char) > 3 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 4 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(char, unsigned long, (((((((((unsigned long)digits[3]) << PyLong_SHIFT) | (unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(char) - 1 > 4 * PyLong_SHIFT) {
                            return (char) ((((((((((char)digits[3]) << PyLong_SHIFT) | (char)digits[2]) << PyLong_SHIFT) | (char)digits[1]) << PyLong_SHIFT) | (char)digits[0])));
                        }
                    }
                    break;
            }
#endif
            if (sizeof(char) <= sizeof(long)) {
                __PYX_VERIFY_RETURN_INT_EXC(char, long, PyLong_AsLong(x))
#ifdef HAVE_LONG_LONG
            } else if (sizeof(char) <= sizeof(PY_LONG_LONG)) {
                __PYX_VERIFY_RETURN_INT_EXC(char, PY_LONG_LONG, PyLong_AsLongLong(x))
#endif
            }
        }
        {
#if CYTHON_COMPILING_IN_PYPY && !defined(_PyLong_AsByteArray)
            PyErr_SetString(PyExc_RuntimeError,
                            "_PyLong_AsByteArray() not available in PyPy, cannot convert large numbers");
#else
            char val;
            PyObject *v = __Pyx_PyNumber_IntOrLong(x);
 #if PY_MAJOR_VERSION < 3
            if (likely(v) && !PyLong_Check(v)) {
                PyObject *tmp = v;
                v = PyNumber_Long(tmp);
                Py_DECREF(tmp);
            }
 #endif
            if (likely(v)) {
                int one = 1; int is_little = (int)*(unsigned char *)&one;
                unsigned char *bytes = (unsigned char *)&val;
                int ret = _PyLong_AsByteArray((PyLongObject *)v,
                                              bytes, sizeof(val),
                                              is_little, !is_unsigned);
                Py_DECREF(v);
                if (likely(!ret))
                    return val;
            }
#endif
            return (char) -1;
        }
    } else {
        char val;
        PyObject *tmp = __Pyx_PyNumber_IntOrLong(x);
        if (!tmp) return (char) -1;
        val = __Pyx_PyInt_As_char(tmp);
        Py_DECREF(tmp);
        return val;
    }
raise_overflow:
    PyErr_SetString(PyExc_OverflowError,
        "value too large to convert to char");
    return (char) -1;
raise_neg_overflow:
    PyErr_SetString(PyExc_OverflowError,
        "can't convert negative value to char");
    return (char) -1;
}

/* IsLittleEndian */
static CYTHON_INLINE int __Pyx_Is_Little_Endian(void)
{
  union {
    uint32_t u32;
    uint8_t u8[4];
  } S;
  S.u32 = 0x01020304;
  return S.u8[0] == 4;
}

/* BufferFormatCheck */
static void __Pyx_BufFmt_Init(__Pyx_BufFmt_Context* ctx,
                              __Pyx_BufFmt_StackElem* stack,
                              __Pyx_TypeInfo* type) {
  stack[0].field = &ctx->root;
  stack[0].parent_offset = 0;
  ctx->root.type = type;
  ctx->root.name = "buffer dtype";
  ctx->root.offset = 0;
  ctx->head = stack;
  ctx->head->field = &ctx->root;
  ctx->fmt_offset = 0;
  ctx->head->parent_offset = 0;
  ctx->new_packmode = '@';
  ctx->enc_packmode = '@';
  ctx->new_count = 1;
  ctx->enc_count = 0;
  ctx->enc_type = 0;
  ctx->is_complex = 0;
  ctx->is_valid_array = 0;
  ctx->struct_alignment = 0;
  while (type->typegroup == 'S') {
    ++ctx->head;
    ctx->head->field = type->fields;
    ctx->head->parent_offset = 0;
    type = type->fields->type;
  }
}
static int __Pyx_BufFmt_ParseNumber(const char** ts) {
    int count;
    const char* t = *ts;
    if (*t < '0' || *t > '9') {
      return -1;
    } else {
        count = *t++ - '0';
        while (*t >= '0' && *t <= '9') {
            count *= 10;
            count += *t++ - '0';
        }
    }
    *ts = t;
    return count;
}
static int __Pyx_BufFmt_ExpectNumber(const char **ts) {
    int number = __Pyx_BufFmt_ParseNumber(ts);
    if (number == -1)
        PyErr_Format(PyExc_ValueError,\
                     "Does not understand character buffer dtype format string ('%c')", **ts);
    return number;
}
static void __Pyx_BufFmt_RaiseUnexpectedChar(char ch) {
  PyErr_Format(PyExc_ValueError,
               "Unexpected format string character: '%c'", ch);
}
static const char* __Pyx_BufFmt_DescribeTypeChar(char ch, int is_complex) {
  switch (ch) {
    case 'c': return "'char'";
    case 'b': return "'signed char'";
    case 'B': return "'unsigned char'";
    case 'h': return "'short'";
    case 'H': return "'unsigned short'";
    case 'i': return "'int'";
    case 'I': return "'unsigned int'";
    case 'l': return "'long'";
    case 'L': return "'unsigned long'";
    case 'q': return "'long long'";
    case 'Q': return "'unsigned long long'";
    case 'f': return (is_complex ? "'complex float'" : "'float'");
    case 'd': return (is_complex ? "'complex double'" : "'double'");
    case 'g': return (is_complex ? "'complex long double'" : "'long double'");
    case 'T': return "a struct";
    case 'O': return "Python object";
    case 'P': return "a pointer";
    case 's': case 'p': return "a string";
    case 0: return "end";
    default: return "unparseable format string";
  }
}
static size_t __Pyx_BufFmt_TypeCharToStandardSize(char ch, int is_complex) {
  switch (ch) {
    case '?': case 'c': case 'b': case 'B': case 's': case 'p': return 1;
    case 'h': case 'H': return 2;
    case 'i': case 'I': case 'l': case 'L': return 4;
    case 'q': case 'Q': return 8;
    case 'f': return (is_complex ? 8 : 4);
    case 'd': return (is_complex ? 16 : 8);
    case 'g': {
      PyErr_SetString(PyExc_ValueError, "Python does not define a standard format string size for long double ('g')..");
      return 0;
    }
    case 'O': case 'P': return sizeof(void*);
    default:
      __Pyx_BufFmt_RaiseUnexpectedChar(ch);
      return 0;
    }
}
static size_t __Pyx_BufFmt_TypeCharToNativeSize(char ch, int is_complex) {
  switch (ch) {
    case 'c': case 'b': case 'B': case 's': case 'p': return 1;
    case 'h': case 'H': return sizeof(short);
    case 'i': case 'I': return sizeof(int);
    case 'l': case 'L': return sizeof(long);
    #ifdef HAVE_LONG_LONG
    case 'q': case 'Q': return sizeof(PY_LONG_LONG);
    #endif
    case 'f': return sizeof(float) * (is_complex ? 2 : 1);
    case 'd': return sizeof(double) * (is_complex ? 2 : 1);
    case 'g': return sizeof(long double) * (is_complex ? 2 : 1);
    case 'O': case 'P': return sizeof(void*);
    default: {
      __Pyx_BufFmt_RaiseUnexpectedChar(ch);
      return 0;
    }
  }
}
typedef struct { char c; short x; } __Pyx_st_short;
typedef struct { char c; int x; } __Pyx_st_int;
typedef struct { char c; long x; } __Pyx_st_long;
typedef struct { char c; float x; } __Pyx_st_float;
typedef struct { char c; double x; } __Pyx_st_double;
typedef struct { char c; long double x; } __Pyx_st_longdouble;
typedef struct { char c; void *x; } __Pyx_st_void_p;
#ifdef HAVE_LONG_LONG
typedef struct { char c; PY_LONG_LONG x; } __Pyx_st_longlong;
#endif
static size_t __Pyx_BufFmt_TypeCharToAlignment(char ch, CYTHON_UNUSED int is_complex) {
  switch (ch) {
    case '?': case 'c': case 'b': case 'B': case 's': case 'p': return 1;
    case 'h': case 'H': return sizeof(__Pyx_st_short) - sizeof(short);
    case 'i': case 'I': return sizeof(__Pyx_st_int) - sizeof(int);
    case 'l': case 'L': return sizeof(__Pyx_st_long) - sizeof(long);
#ifdef HAVE_LONG_LONG
    case 'q': case 'Q': return sizeof(__Pyx_st_longlong) - sizeof(PY_LONG_LONG);
#endif
    case 'f': return sizeof(__Pyx_st_float) - sizeof(float);
    case 'd': return sizeof(__Pyx_st_double) - sizeof(double);
    case 'g': return sizeof(__Pyx_st_longdouble) - sizeof(long double);
    case 'P': case 'O': return sizeof(__Pyx_st_void_p) - sizeof(void*);
    default:
      __Pyx_BufFmt_RaiseUnexpectedChar(ch);
      return 0;
    }
}
/* These are for computing the padding at the end of the struct to align
   on the first member of the struct. This will probably the same as above,
   but we don't have any guarantees.
 */
typedef struct { short x; char c; } __Pyx_pad_short;
typedef struct { int x; char c; } __Pyx_pad_int;
typedef struct { long x; char c; } __Pyx_pad_long;
typedef struct { float x; char c; } __Pyx_pad_float;
typedef struct { double x; char c; } __Pyx_pad_double;
typedef struct { long double x; char c; } __Pyx_pad_longdouble;
typedef struct { void *x; char c; } __Pyx_pad_void_p;
#ifdef HAVE_LONG_LONG
typedef struct { PY_LONG_LONG x; char c; } __Pyx_pad_longlong;
#endif
static size_t __Pyx_BufFmt_TypeCharToPadding(char ch, CYTHON_UNUSED int is_complex) {
  switch (ch) {
    case '?': case 'c': case 'b': case 'B': case 's': case 'p': return 1;
    case 'h': case 'H': return sizeof(__Pyx_pad_short) - sizeof(short);
    case 'i': case 'I': return sizeof(__Pyx_pad_int) - sizeof(int);
    case 'l': case 'L': return sizeof(__Pyx_pad_long) - sizeof(long);
#ifdef HAVE_LONG_LONG
    case 'q': case 'Q': return sizeof(__Pyx_pad_longlong) - sizeof(PY_LONG_LONG);
#endif
    case 'f': return sizeof(__Pyx_pad_float) - sizeof(float);
    case 'd': return sizeof(__Pyx_pad_double) - sizeof(double);
    case 'g': return sizeof(__Pyx_pad_longdouble) - sizeof(long double);
    case 'P': case 'O': return sizeof(__Pyx_pad_void_p) - sizeof(void*);
    default:
      __Pyx_BufFmt_RaiseUnexpectedChar(ch);
      return 0;
    }
}
static char __Pyx_BufFmt_TypeCharToGroup(char ch, int is_complex) {
  switch (ch) {
    case 'c':
        return 'H';
    case 'b': case 'h': case 'i':
    case 'l': case 'q': case 's': case 'p':
        return 'I';
    case 'B': case 'H': case 'I': case 'L': case 'Q':
        return 'U';
    case 'f': case 'd': case 'g':
        return (is_complex ? 'C' : 'R');
    case 'O':
        return 'O';
    case 'P':
        return 'P';
    default: {
      __Pyx_BufFmt_RaiseUnexpectedChar(ch);
      return 0;
    }
  }
}
static void __Pyx_BufFmt_RaiseExpected(__Pyx_BufFmt_Context* ctx) {
  if (ctx->head == NULL || ctx->head->field == &ctx->root) {
    const char* expected;
    const char* quote;
    if (ctx->head == NULL) {
      expected = "end";
      quote = "";
    } else {
      expected = ctx->head->field->type->name;
      quote = "'";
    }
    PyErr_Format(PyExc_ValueError,
                 "Buffer dtype mismatch, expected %s%s%s but got %s",
                 quote, expected, quote,
                 __Pyx_BufFmt_DescribeTypeChar(ctx->enc_type, ctx->is_complex));
  } else {
    __Pyx_StructField* field = ctx->head->field;
    __Pyx_StructField* parent = (ctx->head - 1)->field;
    PyErr_Format(PyExc_ValueError,
                 "Buffer dtype mismatch, expected '%s' but got %s in '%s.%s'",
                 field->type->name, __Pyx_BufFmt_DescribeTypeChar(ctx->enc_type, ctx->is_complex),
                 parent->type->name, field->name);
  }
}
static int __Pyx_BufFmt_ProcessTypeChunk(__Pyx_BufFmt_Context* ctx) {
  char group;
  size_t size, offset, arraysize = 1;
  if (ctx->enc_type == 0) return 0;
  if (ctx->head->field->type->arraysize[0]) {
    int i, ndim = 0;
    if (ctx->enc_type == 's' || ctx->enc_type == 'p') {
        ctx->is_valid_array = ctx->head->field->type->ndim == 1;
        ndim = 1;
        if (ctx->enc_count != ctx->head->field->type->arraysize[0]) {
            PyErr_Format(PyExc_ValueError,
                         "Expected a dimension of size %zu, got %zu",
                         ctx->head->field->type->arraysize[0], ctx->enc_count);
            return -1;
        }
    }
    if (!ctx->is_valid_array) {
      PyErr_Format(PyExc_ValueError, "Expected %d dimensions, got %d",
                   ctx->head->field->type->ndim, ndim);
      return -1;
    }
    for (i = 0; i < ctx->head->field->type->ndim; i++) {
      arraysize *= ctx->head->field->type->arraysize[i];
    }
    ctx->is_valid_array = 0;
    ctx->enc_count = 1;
  }
  group = __Pyx_BufFmt_TypeCharToGroup(ctx->enc_type, ctx->is_complex);
  do {
    __Pyx_StructField* field = ctx->head->field;
    __Pyx_TypeInfo* type = field->type;
    if (ctx->enc_packmode == '@' || ctx->enc_packmode == '^') {
      size = __Pyx_BufFmt_TypeCharToNativeSize(ctx->enc_type, ctx->is_complex);
    } else {
      size = __Pyx_BufFmt_TypeCharToStandardSize(ctx->enc_type, ctx->is_complex);
    }
    if (ctx->enc_packmode == '@') {
      size_t align_at = __Pyx_BufFmt_TypeCharToAlignment(ctx->enc_type, ctx->is_complex);
      size_t align_mod_offset;
      if (align_at == 0) return -1;
      align_mod_offset = ctx->fmt_offset % align_at;
      if (align_mod_offset > 0) ctx->fmt_offset += align_at - align_mod_offset;
      if (ctx->struct_alignment == 0)
          ctx->struct_alignment = __Pyx_BufFmt_TypeCharToPadding(ctx->enc_type,
                                                                 ctx->is_complex);
    }
    if (type->size != size || type->typegroup != group) {
      if (type->typegroup == 'C' && type->fields != NULL) {
        size_t parent_offset = ctx->head->parent_offset + field->offset;
        ++ctx->head;
        ctx->head->field = type->fields;
        ctx->head->parent_offset = parent_offset;
        continue;
      }
      if ((type->typegroup == 'H' || group == 'H') && type->size == size) {
      } else {
          __Pyx_BufFmt_RaiseExpected(ctx);
          return -1;
      }
    }
    offset = ctx->head->parent_offset + field->offset;
    if (ctx->fmt_offset != offset) {
      PyErr_Format(PyExc_ValueError,
                   "Buffer dtype mismatch; next field is at offset %" CYTHON_FORMAT_SSIZE_T "d but %" CYTHON_FORMAT_SSIZE_T "d expected",
                   (Py_ssize_t)ctx->fmt_offset, (Py_ssize_t)offset);
      return -1;
    }
    ctx->fmt_offset += size;
    if (arraysize)
      ctx->fmt_offset += (arraysize - 1) * size;
    --ctx->enc_count;
    while (1) {
      if (field == &ctx->root) {
        ctx->head = NULL;
        if (ctx->enc_count != 0) {
          __Pyx_BufFmt_RaiseExpected(ctx);
          return -1;
        }
        break;
      }
      ctx->head->field = ++field;
      if (field->type == NULL) {
        --ctx->head;
        field = ctx->head->field;
        continue;
      } else if (field->type->typegroup == 'S') {
        size_t parent_offset = ctx->head->parent_offset + field->offset;
        if (field->type->fields->type == NULL) continue;
        field = field->type->fields;
        ++ctx->head;
        ctx->head->field = field;
        ctx->head->parent_offset = parent_offset;
        break;
      } else {
        break;
      }
    }
  } while (ctx->enc_count);
  ctx->enc_type = 0;
  ctx->is_complex = 0;
  return 0;
}
static PyObject *
__pyx_buffmt_parse_array(__Pyx_BufFmt_Context* ctx, const char** tsp)
{
    const char *ts = *tsp;
    int i = 0, number;
    int ndim = ctx->head->field->type->ndim;
;
    ++ts;
    if (ctx->new_count != 1) {
        PyErr_SetString(PyExc_ValueError,
                        "Cannot handle repeated arrays in format string");
        return NULL;
    }
    if (__Pyx_BufFmt_ProcessTypeChunk(ctx) == -1) return NULL;
    while (*ts && *ts != ')') {
        switch (*ts) {
            case ' ': case '\f': case '\r': case '\n': case '\t': case '\v':  continue;
            default:  break;
        }
        number = __Pyx_BufFmt_ExpectNumber(&ts);
        if (number == -1) return NULL;
        if (i < ndim && (size_t) number != ctx->head->field->type->arraysize[i])
            return PyErr_Format(PyExc_ValueError,
                        "Expected a dimension of size %zu, got %d",
                        ctx->head->field->type->arraysize[i], number);
        if (*ts != ',' && *ts != ')')
            return PyErr_Format(PyExc_ValueError,
                                "Expected a comma in format string, got '%c'", *ts);
        if (*ts == ',') ts++;
        i++;
    }
    if (i != ndim)
        return PyErr_Format(PyExc_ValueError, "Expected %d dimension(s), got %d",
                            ctx->head->field->type->ndim, i);
    if (!*ts) {
        PyErr_SetString(PyExc_ValueError,
                        "Unexpected end of format string, expected ')'");
        return NULL;
    }
    ctx->is_valid_array = 1;
    ctx->new_count = 1;
    *tsp = ++ts;
    return Py_None;
}
static const char* __Pyx_BufFmt_CheckString(__Pyx_BufFmt_Context* ctx, const char* ts) {
  int got_Z = 0;
  while (1) {
    switch(*ts) {
      case 0:
        if (ctx->enc_type != 0 && ctx->head == NULL) {
          __Pyx_BufFmt_RaiseExpected(ctx);
          return NULL;
        }
        if (__Pyx_BufFmt_ProcessTypeChunk(ctx) == -1) return NULL;
        if (ctx->head != NULL) {
          __Pyx_BufFmt_RaiseExpected(ctx);
          return NULL;
        }
        return ts;
      case ' ':
      case '\r':
      case '\n':
        ++ts;
        break;
      case '<':
        if (!__Pyx_Is_Little_Endian()) {
          PyErr_SetString(PyExc_ValueError, "Little-endian buffer not supported on big-endian compiler");
          return NULL;
        }
        ctx->new_packmode = '=';
        ++ts;
        break;
      case '>':
      case '!':
        if (__Pyx_Is_Little_Endian()) {
          PyErr_SetString(PyExc_ValueError, "Big-endian buffer not supported on little-endian compiler");
          return NULL;
        }
        ctx->new_packmode = '=';
        ++ts;
        break;
      case '=':
      case '@':
      case '^':
        ctx->new_packmode = *ts++;
        break;
      case 'T':
        {
          const char* ts_after_sub;
          size_t i, struct_count = ctx->new_count;
          size_t struct_alignment = ctx->struct_alignment;
          ctx->new_count = 1;
          ++ts;
          if (*ts != '{') {
            PyErr_SetString(PyExc_ValueError, "Buffer acquisition: Expected '{' after 'T'");
            return NULL;
          }
          if (__Pyx_BufFmt_ProcessTypeChunk(ctx) == -1) return NULL;
          ctx->enc_type = 0;
          ctx->enc_count = 0;
          ctx->struct_alignment = 0;
          ++ts;
          ts_after_sub = ts;
          for (i = 0; i != struct_count; ++i) {
            ts_after_sub = __Pyx_BufFmt_CheckString(ctx, ts);
            if (!ts_after_sub) return NULL;
          }
          ts = ts_after_sub;
          if (struct_alignment) ctx->struct_alignment = struct_alignment;
        }
        break;
      case '}':
        {
          size_t alignment = ctx->struct_alignment;
          ++ts;
          if (__Pyx_BufFmt_ProcessTypeChunk(ctx) == -1) return NULL;
          ctx->enc_type = 0;
          if (alignment && ctx->fmt_offset % alignment) {
            ctx->fmt_offset += alignment - (ctx->fmt_offset % alignment);
          }
        }
        return ts;
      case 'x':
        if (__Pyx_BufFmt_ProcessTypeChunk(ctx) == -1) return NULL;
        ctx->fmt_offset += ctx->new_count;
        ctx->new_count = 1;
        ctx->enc_count = 0;
        ctx->enc_type = 0;
        ctx->enc_packmode = ctx->new_packmode;
        ++ts;
        break;
      case 'Z':
        got_Z = 1;
        ++ts;
        if (*ts != 'f' && *ts != 'd' && *ts != 'g') {
          __Pyx_BufFmt_RaiseUnexpectedChar('Z');
          return NULL;
        }
        CYTHON_FALLTHROUGH;
      case 'c': case 'b': case 'B': case 'h': case 'H': case 'i': case 'I':
      case 'l': case 'L': case 'q': case 'Q':
      case 'f': case 'd': case 'g':
      case 'O': case 'p':
        if (ctx->enc_type == *ts && got_Z == ctx->is_complex &&
            ctx->enc_packmode == ctx->new_packmode) {
          ctx->enc_count += ctx->new_count;
          ctx->new_count = 1;
          got_Z = 0;
          ++ts;
          break;
        }
        CYTHON_FALLTHROUGH;
      case 's':
        if (__Pyx_BufFmt_ProcessTypeChunk(ctx) == -1) return NULL;
        ctx->enc_count = ctx->new_count;
        ctx->enc_packmode = ctx->new_packmode;
        ctx->enc_type = *ts;
        ctx->is_complex = got_Z;
        ++ts;
        ctx->new_count = 1;
        got_Z = 0;
        break;
      case ':':
        ++ts;
        while(*ts != ':') ++ts;
        ++ts;
        break;
      case '(':
        if (!__pyx_buffmt_parse_array(ctx, &ts)) return NULL;
        break;
      default:
        {
          int number = __Pyx_BufFmt_ExpectNumber(&ts);
          if (number == -1) return NULL;
          ctx->new_count = (size_t)number;
        }
    }
  }
}

/* TypeInfoCompare */
  static int
__pyx_typeinfo_cmp(__Pyx_TypeInfo *a, __Pyx_TypeInfo *b)
{
    int i;
    if (!a || !b)
        return 0;
    if (a == b)
        return 1;
    if (a->size != b->size || a->typegroup != b->typegroup ||
            a->is_unsigned != b->is_unsigned || a->ndim != b->ndim) {
        if (a->typegroup == 'H' || b->typegroup == 'H') {
            return a->size == b->size;
        } else {
            return 0;
        }
    }
    if (a->ndim) {
        for (i = 0; i < a->ndim; i++)
            if (a->arraysize[i] != b->arraysize[i])
                return 0;
    }
    if (a->typegroup == 'S') {
        if (a->flags != b->flags)
            return 0;
        if (a->fields || b->fields) {
            if (!(a->fields && b->fields))
                return 0;
            for (i = 0; a->fields[i].type && b->fields[i].type; i++) {
                __Pyx_StructField *field_a = a->fields + i;
                __Pyx_StructField *field_b = b->fields + i;
                if (field_a->offset != field_b->offset ||
                    !__pyx_typeinfo_cmp(field_a->type, field_b->type))
                    return 0;
            }
            return !a->fields[i].type && !b->fields[i].type;
        }
    }
    return 1;
}

/* MemviewSliceValidateAndInit */
  static int
__pyx_check_strides(Py_buffer *buf, int dim, int ndim, int spec)
{
    if (buf->shape[dim] <= 1)
        return 1;
    if (buf->strides) {
        if (spec & __Pyx_MEMVIEW_CONTIG) {
            if (spec & (__Pyx_MEMVIEW_PTR|__Pyx_MEMVIEW_FULL)) {
                if (buf->strides[dim] != sizeof(void *)) {
                    PyErr_Format(PyExc_ValueError,
                                 "Buffer is not indirectly contiguous "
                                 "in dimension %d.", dim);
                    goto fail;
                }
            } else if (buf->strides[dim] != buf->itemsize) {
                PyErr_SetString(PyExc_ValueError,
                                "Buffer and memoryview are not contiguous "
                                "in the same dimension.");
                goto fail;
            }
        }
        if (spec & __Pyx_MEMVIEW_FOLLOW) {
            Py_ssize_t stride = buf->strides[dim];
            if (stride < 0)
                stride = -stride;
            if (stride < buf->itemsize) {
                PyErr_SetString(PyExc_ValueError,
                                "Buffer and memoryview are not contiguous "
                                "in the same dimension.");
                goto fail;
            }
        }
    } else {
        if (spec & __Pyx_MEMVIEW_CONTIG && dim != ndim - 1) {
            PyErr_Format(PyExc_ValueError,
                         "C-contiguous buffer is not contiguous in "
                         "dimension %d", dim);
            goto fail;
        } else if (spec & (__Pyx_MEMVIEW_PTR)) {
            PyErr_Format(PyExc_ValueError,
                         "C-contiguous buffer is not indirect in "
                         "dimension %d", dim);
            goto fail;
        } else if (buf->suboffsets) {
            PyErr_SetString(PyExc_ValueError,
                            "Buffer exposes suboffsets but no strides");
            goto fail;
        }
    }
    return 1;
fail:
    return 0;
}
static int
__pyx_check_suboffsets(Py_buffer *buf, int dim, CYTHON_UNUSED int ndim, int spec)
{
    if (spec & __Pyx_MEMVIEW_DIRECT) {
        if (buf->suboffsets && buf->suboffsets[dim] >= 0) {
            PyErr_Format(PyExc_ValueError,
                         "Buffer not compatible with direct access "
                         "in dimension %d.", dim);
            goto fail;
        }
    }
    if (spec & __Pyx_MEMVIEW_PTR) {
        if (!buf->suboffsets || (buf->suboffsets[dim] < 0)) {
            PyErr_Format(PyExc_ValueError,
                         "Buffer is not indirectly accessible "
                         "in dimension %d.", dim);
            goto fail;
        }
    }
    return 1;
fail:
    return 0;
}
static int
__pyx_verify_contig(Py_buffer *buf, int ndim, int c_or_f_flag)
{
    int i;
    if (c_or_f_flag & __Pyx_IS_F_CONTIG) {
        Py_ssize_t stride = 1;
        for (i = 0; i < ndim; i++) {
            if (stride * buf->itemsize != buf->strides[i] &&
                    buf->shape[i] > 1)
            {
                PyErr_SetString(PyExc_ValueError,
                    "Buffer not fortran contiguous.");
                goto fail;
            }
            stride = stride * buf->shape[i];
        }
    } else if (c_or_f_flag & __Pyx_IS_C_CONTIG) {
        Py_ssize_t stride = 1;
        for (i = ndim - 1; i >- 1; i--) {
            if (stride * buf->itemsize != buf->strides[i] &&
                    buf->shape[i] > 1) {
                PyErr_SetString(PyExc_ValueError,
                    "Buffer not C contiguous.");
                goto fail;
            }
            stride = stride * buf->shape[i];
        }
    }
    return 1;
fail:
    return 0;
}
static int __Pyx_ValidateAndInit_memviewslice(
                int *axes_specs,
                int c_or_f_flag,
                int buf_flags,
                int ndim,
                __Pyx_TypeInfo *dtype,
                __Pyx_BufFmt_StackElem stack[],
                __Pyx_memviewslice *memviewslice,
                PyObject *original_obj)
{
    struct __pyx_memoryview_obj *memview, *new_memview;
    __Pyx_RefNannyDeclarations
    Py_buffer *buf;
    int i, spec = 0, retval = -1;
    __Pyx_BufFmt_Context ctx;
    int from_memoryview = __pyx_memoryview_check(original_obj);
    __Pyx_RefNannySetupContext("ValidateAndInit_memviewslice", 0);
    if (from_memoryview && __pyx_typeinfo_cmp(dtype, ((struct __pyx_memoryview_obj *)
                                                            original_obj)->typeinfo)) {
        memview = (struct __pyx_memoryview_obj *) original_obj;
        new_memview = NULL;
    } else {
        memview = (struct __pyx_memoryview_obj *) __pyx_memoryview_new(
                                            original_obj, buf_flags, 0, dtype);
        new_memview = memview;
        if (unlikely(!memview))
            goto fail;
    }
    buf = &memview->view;
    if (buf->ndim != ndim) {
        PyErr_Format(PyExc_ValueError,
                "Buffer has wrong number of dimensions (expected %d, got %d)",
                ndim, buf->ndim);
        goto fail;
    }
    if (new_memview) {
        __Pyx_BufFmt_Init(&ctx, stack, dtype);
        if (!__Pyx_BufFmt_CheckString(&ctx, buf->format)) goto fail;
    }
    if ((unsigned) buf->itemsize != dtype->size) {
        PyErr_Format(PyExc_ValueError,
                     "Item size of buffer (%" CYTHON_FORMAT_SSIZE_T "u byte%s) "
                     "does not match size of '%s' (%" CYTHON_FORMAT_SSIZE_T "u byte%s)",
                     buf->itemsize,
                     (buf->itemsize > 1) ? "s" : "",
                     dtype->name,
                     dtype->size,
                     (dtype->size > 1) ? "s" : "");
        goto fail;
    }
    for (i = 0; i < ndim; i++) {
        spec = axes_specs[i];
        if (!__pyx_check_strides(buf, i, ndim, spec))
            goto fail;
        if (!__pyx_check_suboffsets(buf, i, ndim, spec))
            goto fail;
    }
    if (buf->strides && !__pyx_verify_contig(buf, ndim, c_or_f_flag))
        goto fail;
    if (unlikely(__Pyx_init_memviewslice(memview, ndim, memviewslice,
                                         new_memview != NULL) == -1)) {
        goto fail;
    }
    retval = 0;
    goto no_fail;
fail:
    Py_XDECREF(new_memview);
    retval = -1;
no_fail:
    __Pyx_RefNannyFinishContext();
    return retval;
}

/* ObjectToMemviewSlice */
  static CYTHON_INLINE __Pyx_memviewslice __Pyx_PyObject_to_MemoryviewSlice_dsds_double(PyObject *obj, int writable_flag) {
    __Pyx_memviewslice result = { 0, 0, { 0 }, { 0 }, { 0 } };
    __Pyx_BufFmt_StackElem stack[1];
    int axes_specs[] = { (__Pyx_MEMVIEW_DIRECT | __Pyx_MEMVIEW_STRIDED), (__Pyx_MEMVIEW_DIRECT | __Pyx_MEMVIEW_STRIDED) };
    int retcode;
    if (obj == Py_None) {
        result.memview = (struct __pyx_memoryview_obj *) Py_None;
        return result;
    }
    retcode = __Pyx_ValidateAndInit_memviewslice(axes_specs, 0,
                                                 PyBUF_RECORDS_RO | writable_flag, 2,
                                                 &__Pyx_TypeInfo_double, stack,
                                                 &result, obj);
    if (unlikely(retcode == -1))
        goto __pyx_fail;
    return result;
__pyx_fail:
    result.memview = NULL;
    result.data = NULL;
    return result;
}

/* ObjectToMemviewSlice */
  static CYTHON_INLINE __Pyx_memviewslice __Pyx_PyObject_to_MemoryviewSlice_ds_double(PyObject *obj, int writable_flag) {
    __Pyx_memviewslice result = { 0, 0, { 0 }, { 0 }, { 0 } };
    __Pyx_BufFmt_StackElem stack[1];
    int axes_specs[] = { (__Pyx_MEMVIEW_DIRECT | __Pyx_MEMVIEW_STRIDED) };
    int retcode;
    if (obj == Py_None) {
        result.memview = (struct __pyx_memoryview_obj *) Py_None;
        return result;
    }
    retcode = __Pyx_ValidateAndInit_memviewslice(axes_specs, 0,
                                                 PyBUF_RECORDS_RO | writable_flag, 1,
                                                 &__Pyx_TypeInfo_double, stack,
                                                 &result, obj);
    if (unlikely(retcode == -1))
        goto __pyx_fail;
    return result;
__pyx_fail:
    result.memview = NULL;
    result.data = NULL;
    return result;
}

/* CheckBinaryVersion */
  static int __Pyx_check_binary_version(void) {
    char ctversion[4], rtversion[4];
    PyOS_snprintf(ctversion, 4, "%d.%d", PY_MAJOR_VERSION, PY_MINOR_VERSION);
    PyOS_snprintf(rtversion, 4, "%s", Py_GetVersion());
    if (ctversion[0] != rtversion[0] || ctversion[2] != rtversion[2]) {
        char message[200];
        PyOS_snprintf(message, sizeof(message),
                      "compiletime version %s of module '%.100s' "
                      "does not match runtime version %s",
                      ctversion, __Pyx_MODULE_NAME, rtversion);
        return PyErr_WarnEx(NULL, message, 1);
    }
    return 0;
}

/* InitStrings */
  static int __Pyx_InitStrings(__Pyx_StringTabEntry *t) {
    while (t->p) {
        #if PY_MAJOR_VERSION < 3
        if (t->is_unicode) {
            *t->p = PyUnicode_DecodeUTF8(t->s, t->n - 1, NULL);
        } else if (t->intern) {
            *t->p = PyString_InternFromString(t->s);
        } else {
            *t->p = PyString_FromStringAndSize(t->s, t->n - 1);
        }
        #else
        if (t->is_unicode | t->is_str) {
            if (t->intern) {
                *t->p = PyUnicode_InternFromString(t->s);
            } else if (t->encoding) {
                *t->p = PyUnicode_Decode(t->s, t->n - 1, t->encoding, NULL);
            } else {
                *t->p = PyUnicode_FromStringAndSize(t->s, t->n - 1);
            }
        } else {
            *t->p = PyBytes_FromStringAndSize(t->s, t->n - 1);
        }
        #endif
        if (!*t->p)
            return -1;
        if (PyObject_Hash(*t->p) == -1)
            return -1;
        ++t;
    }
    return 0;
}

static CYTHON_INLINE PyObject* __Pyx_PyUnicode_FromString(const char* c_str) {
    return __Pyx_PyUnicode_FromStringAndSize(c_str, (Py_ssize_t)strlen(c_str));
}
static CYTHON_INLINE const char* __Pyx_PyObject_AsString(PyObject* o) {
    Py_ssize_t ignore;
    return __Pyx_PyObject_AsStringAndSize(o, &ignore);
}
#if __PYX_DEFAULT_STRING_ENCODING_IS_ASCII || __PYX_DEFAULT_STRING_ENCODING_IS_DEFAULT
#if !CYTHON_PEP393_ENABLED
static const char* __Pyx_PyUnicode_AsStringAndSize(PyObject* o, Py_ssize_t *length) {
    char* defenc_c;
    PyObject* defenc = _PyUnicode_AsDefaultEncodedString(o, NULL);
    if (!defenc) return NULL;
    defenc_c = PyBytes_AS_STRING(defenc);
#if __PYX_DEFAULT_STRING_ENCODING_IS_ASCII
    {
        char* end = defenc_c + PyBytes_GET_SIZE(defenc);
        char* c;
        for (c = defenc_c; c < end; c++) {
            if ((unsigned char) (*c) >= 128) {
                PyUnicode_AsASCIIString(o);
                return NULL;
            }
        }
    }
#endif
    *length = PyBytes_GET_SIZE(defenc);
    return defenc_c;
}
#else
static CYTHON_INLINE const char* __Pyx_PyUnicode_AsStringAndSize(PyObject* o, Py_ssize_t *length) {
    if (unlikely(__Pyx_PyUnicode_READY(o) == -1)) return NULL;
#if __PYX_DEFAULT_STRING_ENCODING_IS_ASCII
    if (likely(PyUnicode_IS_ASCII(o))) {
        *length = PyUnicode_GET_LENGTH(o);
        return PyUnicode_AsUTF8(o);
    } else {
        PyUnicode_AsASCIIString(o);
        return NULL;
    }
#else
    return PyUnicode_AsUTF8AndSize(o, length);
#endif
}
#endif
#endif
static CYTHON_INLINE const char* __Pyx_PyObject_AsStringAndSize(PyObject* o, Py_ssize_t *length) {
#if __PYX_DEFAULT_STRING_ENCODING_IS_ASCII || __PYX_DEFAULT_STRING_ENCODING_IS_DEFAULT
    if (
#if PY_MAJOR_VERSION < 3 && __PYX_DEFAULT_STRING_ENCODING_IS_ASCII
            __Pyx_sys_getdefaultencoding_not_ascii &&
#endif
            PyUnicode_Check(o)) {
        return __Pyx_PyUnicode_AsStringAndSize(o, length);
    } else
#endif
#if (!CYTHON_COMPILING_IN_PYPY) || (defined(PyByteArray_AS_STRING) && defined(PyByteArray_GET_SIZE))
    if (PyByteArray_Check(o)) {
        *length = PyByteArray_GET_SIZE(o);
        return PyByteArray_AS_STRING(o);
    } else
#endif
    {
        char* result;
        int r = PyBytes_AsStringAndSize(o, &result, length);
        if (unlikely(r < 0)) {
            return NULL;
        } else {
            return result;
        }
    }
}
static CYTHON_INLINE int __Pyx_PyObject_IsTrue(PyObject* x) {
   int is_true = x == Py_True;
   if (is_true | (x == Py_False) | (x == Py_None)) return is_true;
   else return PyObject_IsTrue(x);
}
static CYTHON_INLINE int __Pyx_PyObject_IsTrueAndDecref(PyObject* x) {
    int retval;
    if (unlikely(!x)) return -1;
    retval = __Pyx_PyObject_IsTrue(x);
    Py_DECREF(x);
    return retval;
}
static PyObject* __Pyx_PyNumber_IntOrLongWrongResultType(PyObject* result, const char* type_name) {
#if PY_MAJOR_VERSION >= 3
    if (PyLong_Check(result)) {
        if (PyErr_WarnFormat(PyExc_DeprecationWarning, 1,
                "__int__ returned non-int (type %.200s).  "
                "The ability to return an instance of a strict subclass of int "
                "is deprecated, and may be removed in a future version of Python.",
                Py_TYPE(result)->tp_name)) {
            Py_DECREF(result);
            return NULL;
        }
        return result;
    }
#endif
    PyErr_Format(PyExc_TypeError,
                 "__%.4s__ returned non-%.4s (type %.200s)",
                 type_name, type_name, Py_TYPE(result)->tp_name);
    Py_DECREF(result);
    return NULL;
}
static CYTHON_INLINE PyObject* __Pyx_PyNumber_IntOrLong(PyObject* x) {
#if CYTHON_USE_TYPE_SLOTS
  PyNumberMethods *m;
#endif
  const char *name = NULL;
  PyObject *res = NULL;
#if PY_MAJOR_VERSION < 3
  if (likely(PyInt_Check(x) || PyLong_Check(x)))
#else
  if (likely(PyLong_Check(x)))
#endif
    return __Pyx_NewRef(x);
#if CYTHON_USE_TYPE_SLOTS
  m = Py_TYPE(x)->tp_as_number;
  #if PY_MAJOR_VERSION < 3
  if (m && m->nb_int) {
    name = "int";
    res = m->nb_int(x);
  }
  else if (m && m->nb_long) {
    name = "long";
    res = m->nb_long(x);
  }
  #else
  if (likely(m && m->nb_int)) {
    name = "int";
    res = m->nb_int(x);
  }
  #endif
#else
  if (!PyBytes_CheckExact(x) && !PyUnicode_CheckExact(x)) {
    res = PyNumber_Int(x);
  }
#endif
  if (likely(res)) {
#if PY_MAJOR_VERSION < 3
    if (unlikely(!PyInt_Check(res) && !PyLong_Check(res))) {
#else
    if (unlikely(!PyLong_CheckExact(res))) {
#endif
        return __Pyx_PyNumber_IntOrLongWrongResultType(res, name);
    }
  }
  else if (!PyErr_Occurred()) {
    PyErr_SetString(PyExc_TypeError,
                    "an integer is required");
  }
  return res;
}
static CYTHON_INLINE Py_ssize_t __Pyx_PyIndex_AsSsize_t(PyObject* b) {
  Py_ssize_t ival;
  PyObject *x;
#if PY_MAJOR_VERSION < 3
  if (likely(PyInt_CheckExact(b))) {
    if (sizeof(Py_ssize_t) >= sizeof(long))
        return PyInt_AS_LONG(b);
    else
        return PyInt_AsSsize_t(b);
  }
#endif
  if (likely(PyLong_CheckExact(b))) {
    #if CYTHON_USE_PYLONG_INTERNALS
    const digit* digits = ((PyLongObject*)b)->ob_digit;
    const Py_ssize_t size = Py_SIZE(b);
    if (likely(__Pyx_sst_abs(size) <= 1)) {
        ival = likely(size) ? digits[0] : 0;
        if (size == -1) ival = -ival;
        return ival;
    } else {
      switch (size) {
         case 2:
           if (8 * sizeof(Py_ssize_t) > 2 * PyLong_SHIFT) {
             return (Py_ssize_t) (((((size_t)digits[1]) << PyLong_SHIFT) | (size_t)digits[0]));
           }
           break;
         case -2:
           if (8 * sizeof(Py_ssize_t) > 2 * PyLong_SHIFT) {
             return -(Py_ssize_t) (((((size_t)digits[1]) << PyLong_SHIFT) | (size_t)digits[0]));
           }
           break;
         case 3:
           if (8 * sizeof(Py_ssize_t) > 3 * PyLong_SHIFT) {
             return (Py_ssize_t) (((((((size_t)digits[2]) << PyLong_SHIFT) | (size_t)digits[1]) << PyLong_SHIFT) | (size_t)digits[0]));
           }
           break;
         case -3:
           if (8 * sizeof(Py_ssize_t) > 3 * PyLong_SHIFT) {
             return -(Py_ssize_t) (((((((size_t)digits[2]) << PyLong_SHIFT) | (size_t)digits[1]) << PyLong_SHIFT) | (size_t)digits[0]));
           }
           break;
         case 4:
           if (8 * sizeof(Py_ssize_t) > 4 * PyLong_SHIFT) {
             return (Py_ssize_t) (((((((((size_t)digits[3]) << PyLong_SHIFT) | (size_t)digits[2]) << PyLong_SHIFT) | (size_t)digits[1]) << PyLong_SHIFT) | (size_t)digits[0]));
           }
           break;
         case -4:
           if (8 * sizeof(Py_ssize_t) > 4 * PyLong_SHIFT) {
             return -(Py_ssize_t) (((((((((size_t)digits[3]) << PyLong_SHIFT) | (size_t)digits[2]) << PyLong_SHIFT) | (size_t)digits[1]) << PyLong_SHIFT) | (size_t)digits[0]));
           }
           break;
      }
    }
    #endif
    return PyLong_AsSsize_t(b);
  }
  x = PyNumber_Index(b);
  if (!x) return -1;
  ival = PyInt_AsSsize_t(x);
  Py_DECREF(x);
  return ival;
}
static CYTHON_INLINE PyObject * __Pyx_PyBool_FromLong(long b) {
  return b ? __Pyx_NewRef(Py_True) : __Pyx_NewRef(Py_False);
}
static CYTHON_INLINE PyObject * __Pyx_PyInt_FromSize_t(size_t ival) {
    return PyInt_FromSize_t(ival);
}


#endif /* Py_PYTHON_H */
