/* Generated by Cython 0.29.13 */

/* BEGIN: Cython Metadata
{
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}
END: Cython Metadata */

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  #define __Pyx_PyBaseString_Check(obj) (PyString_Check(obj) || PyUnicode_Check(obj))
  #define __Pyx_PyBaseString_CheckExact(obj) (PyString_CheckExact(obj) || PyUnicode_CheckExact(obj))
#endif
#ifndef PySet_CheckExact
  #define PySet_CheckExact(obj)        (Py_TYPE(obj) == &PySet_Type)
#endif
#if CYTHON_ASSUME_SAFE_MACROS
  #define __Pyx_PySequence_SIZE(seq)  Py_SIZE(seq)
#else
  #define __Pyx_PySequence_SIZE(seq)  PySequence_Size(seq)
#endif
#if PY_MAJOR_VERSION >= 3
  #define PyIntObject                  PyLongObject
  #define PyInt_Type                   PyLong_Type
  #define PyInt_Check(op)              PyLong_Check(op)
  #define PyInt_CheckExact(op)         PyLong_CheckExact(op)
  #define PyInt_FromString             PyLong_FromString
  #define PyInt_FromUnicode            PyLong_FromUnicode
  #define PyInt_FromLong               PyLong_FromLong
  #define PyInt_FromSize_t             PyLong_FromSize_t
  #define PyInt_FromSsize_t            PyLong_FromSsize_t
  #define PyInt_AsLong                 PyLong_AsLong
  #define PyInt_AS_LONG                PyLong_AS_LONG
  #define PyInt_AsSsize_t              PyLong_AsSsize_t
  #define PyInt_AsUnsignedLongMask     PyLong_AsUnsignedLongMask
  #define PyInt_AsUnsignedLongLongMask PyLong_AsUnsignedLongLongMask
  #define PyNumber_Int                 PyNumber_Long
#endif
#if PY_MAJOR_VERSION >= 3
  #define PyBoolObject                 PyLongObject
#endif
#if PY_MAJOR_VERSION >= 3 && CYTHON_COMPILING_IN_PYPY
  #ifndef PyUnicode_InternFromString
    #define PyUnicode_InternFromString(s) PyUnicode_FromString(s)
  #endif
#endif
#if PY_VERSION_HEX < 0x030200A4
  typedef long Py_hash_t;
  #define __Pyx_PyInt_FromHash_t PyInt_FromLong
  #define __Pyx_PyInt_AsHash_t   PyInt_AsLong
#else
  #define __Pyx_PyInt_FromHash_t PyInt_FromSsize_t
  #define __Pyx_PyInt_AsHash_t   PyInt_AsSsize_t
#endif
#if PY_MAJOR_VERSION >= 3
  #define __Pyx_PyMethod_New(func, self, klass) ((self) ? PyMethod_New(func, self) : (Py_INCREF(func), func))
#else
  #define __Pyx_PyMethod_New(func, self, klass) PyMethod_New(func, self, klass)
#endif
#if CYTHON_USE_ASYNC_SLOTS
  #if PY_VERSION_HEX >= 0x030500B1
    #define __Pyx_PyAsyncMethodsStruct PyAsyncMethods
    #define __Pyx_PyType_AsAsync(obj) (Py_TYPE(obj)->tp_as_async)
  #else
    #define __Pyx_PyType_AsAsync(obj) ((__Pyx_PyAsyncMethodsStruct*) (Py_TYPE(obj)->tp_reserved))
  #endif
#else
  #define __Pyx_PyType_AsAsync(obj) NULL
#endif
#ifndef __Pyx_PyAsyncMethodsStruct
    typedef struct {
        unaryfunc am_await;
        unaryfunc am_aiter;
        unaryfunc am_anext;
    } __Pyx_PyAsyncMethodsStruct;
#endif

#if defined(WIN32) || defined(MS_WINDOWS)
  #define _USE_MATH_DEFINES
#endif
#include <math.h>
#ifdef NAN
#define __PYX_NAN() ((float) NAN)
#else
static CYTHON_INLINE float __PYX_NAN() {
  float value;
  memset(&value, 0xFF, sizeof(value));
  return value;
}
#endif
#if defined(__CYGWIN__) && defined(_LDBL_EQ_DBL)
#define __Pyx_truncl trunc
#else
#define __Pyx_truncl truncl
#endif


#define __PYX_ERR(f_index, lineno, Ln_error) \
{ \
  __pyx_filename = __pyx_f[f_index]; __pyx_lineno = lineno; __pyx_clineno = __LINE__; goto Ln_error; \
}

#ifndef __PYX_EXTERN_C
  #ifdef __cplusplus
    #define __PYX_EXTERN_C extern "C"
  #else
    #define __PYX_EXTERN_C extern
  #endif
#endif

#define __PYX_HAVE___rnaseq_utils
#define __PYX_HAVE_API___rnaseq_utils
/* Early includes */
#include <string.h>
#include <stdio.h>
#include "pythread.h"
#include "numpy/arrayobject.h"
#include "numpy/ufuncobject.h"
#include <stdlib.h>
#include "pystate.h"
#ifdef _OPENMP
#include <omp.h>
#endif /* _OPENMP */

#if defined(PYREX_WITHOUT_ASSERTIONS) && !defined(CYTHON_WITHOUT_ASSERTIONS)
#define CYTHON_WITHOUT_ASSERTIONS
#endif

typedef struct {PyObject **p; const char *s; const Py_ssize_t n; const char* encoding;
                const char is_unicode; const char is_str; const char intern; } __Pyx_StringTabEntry;

#define __PYX_DEFAULT_STRING_ENCODING_IS_ASCII 0
#define __PYX_DEFAULT_STRING_ENCODING_IS_UTF8 0
#define __PYX_DEFAULT_STRING_ENCODING_IS_DEFAULT (PY_MAJOR_VERSION >= 3 && __PYX_DEFAULT_STRING_ENCODING_IS_UTF8)
#define __PYX_DEFAULT_STRING_ENCODING ""
#define __Pyx_PyObject_FromString __Pyx_PyBytes_FromString
#define __Pyx_PyObject_FromStringAndSize __Pyx_PyBytes_FromStringAndSize
#define __Pyx_uchar_cast(c) ((unsigned char)c)
#define __Pyx_long_cast(x) ((long)x)
#define __Pyx_fits_Py_ssize_t(v, type, is_signed)  (\
    (sizeof(type) < sizeof(Py_ssize_t))  ||\
    (sizeof(type) > sizeof(Py_ssize_t) &&\
          likely(v < (type)PY_SSIZE_T_MAX ||\
                 v == (type)PY_SSIZE_T_MAX)  &&\
          (!is_signed || likely(v > (type)PY_SSIZE_T_MIN ||\
                                v == (type)PY_SSIZE_T_MIN)))  ||\
    (sizeof(type) == sizeof(Py_ssize_t) &&\
          (is_signed || likely(v < (type)PY_SSIZE_T_MAX ||\
                               v == (type)PY_SSIZE_T_MAX)))  )
static CYTHON_INLINE int __Pyx_is_valid_index(Py_ssize_t i, Py_ssize_t limit) {
    return (size_t) i < (size_t) limit;
}
#if defined (__cplusplus) && __cplusplus >= 201103L
    #include <cstdlib>
    #define __Pyx_sst_abs(value) std::abs(value)
#elif SIZEOF_INT >= SIZEOF_SIZE_T
    #define __Pyx_sst_abs(value) abs(value)
#elif SIZEOF_LONG >= SIZEOF_SIZE_T
    #define __Pyx_sst_abs(value) labs(value)
#elif defined (_MSC_VER)
    #define __Pyx_sst_abs(value) ((Py_ssize_t)_abs64(value))
#elif defined (__STDC_VERSION__) && __STDC_VERSION__ >= 199901L
    #define __Pyx_sst_abs(value) llabs(value)
#elif defined (__GNUC__)
    #define __Pyx_sst_abs(value) __builtin_llabs(value)
#else
    #define __Pyx_sst_abs(value) ((value<0) ? -value : value)
#endif
static CYTHON_INLINE const char* __Pyx_PyObject_AsString(PyObject*);
static CYTHON_INLINE const char* __Pyx_PyObject_AsStringAndSize(PyObject*, Py_ssize_t* length);
#define __Pyx_PyByteArray_FromString(s) PyByteArray_FromStringAndSize((const char*)s, strlen((const char*)s))
#define __Pyx_PyByteArray_FromStringAndSize(s, l) PyByteArray_FromStringAndSize((const char*)s, l)
#define __Pyx_PyBytes_FromString        PyBytes_FromString
#define __Pyx_PyBytes_FromStringAndSize PyBytes_FromStringAndSize
static CYTHON_INLINE PyObject* __Pyx_PyUnicode_FromString(const char*);
#if PY_MAJOR_VERSION < 3
    #define __Pyx_PyStr_FromString        __Pyx_PyBytes_FromString
    #define __Pyx_PyStr_FromStringAndSize __Pyx_PyBytes_FromStringAndSize
#else
    #define __Pyx_PyStr_FromString        __Pyx_PyUnicode_FromString
    #define __Pyx_PyStr_FromStringAndSize __Pyx_PyUnicode_FromStringAndSize
#endif
#define __Pyx_PyBytes_AsWritableString(s)     ((char*) PyBytes_AS_STRING(s))
#define __Pyx_PyBytes_AsWritableSString(s)    ((signed char*) PyBytes_AS_STRING(s))
#define __Pyx_PyBytes_AsWritableUString(s)    ((unsigned char*) PyBytes_AS_STRING(s))
#define __Pyx_PyBytes_AsString(s)     ((const char*) PyBytes_AS_STRING(s))
#define __Pyx_PyBytes_AsSString(s)    ((const signed char*) PyBytes_AS_STRING(s))
#define __Pyx_PyBytes_AsUString(s)    ((const unsigned char*) PyBytes_AS_STRING(s))
#define __Pyx_PyObject_AsWritableString(s)    ((char*) __Pyx_PyObject_AsString(s))
#define __Pyx_PyObject_AsWritableSString(s)    ((signed char*) __Pyx_PyObject_AsString(s))
#define __Pyx_PyObject_AsWritableUString(s)    ((unsigned char*) __Pyx_PyObject_AsString(s))
#define __Pyx_PyObject_AsSString(s)    ((const signed char*) __Pyx_PyObject_AsString(s))
#define __Pyx_PyObject_AsUString(s)    ((const unsigned char*) __Pyx_PyObject_AsString(s))
#define __Pyx_PyObject_FromCString(s)  __Pyx_PyObject_FromString((const char*)s)
#define __Pyx_PyBytes_FromCString(s)   __Pyx_PyBytes_FromString((const char*)s)
#define __Pyx_PyByteArray_FromCString(s)   __Pyx_PyByteArray_FromString((const char*)s)
#define __Pyx_PyStr_FromCString(s)     __Pyx_PyStr_FromString((const char*)s)
#define __Pyx_PyUnicode_FromCString(s) __Pyx_PyUnicode_FromString((const char*)s)
static CYTHON_INLINE size_t __Pyx_Py_UNICODE_strlen(const Py_UNICODE *u) {
    const Py_UNICODE *u_end = u;
    while (*u_end++) ;
    return (size_t)(u_end - u - 1);
}
#define __Pyx_PyUnicode_FromUnicode(u)       PyUnicode_FromUnicode(u, __Pyx_Py_UNICODE_strlen(u))
#define __Pyx_PyUnicode_FromUnicodeAndLength PyUnicode_FromUnicode
#define __Pyx_PyUnicode_AsUnicode            PyUnicode_AsUnicode
#define __Pyx_NewRef(obj) (Py_INCREF(obj), obj)
#define __Pyx_Owned_Py_None(b) __Pyx_NewRef(Py_None)
static CYTHON_INLINE PyObject * __Pyx_PyBool_FromLong(long b);
static CYTHON_INLINE int __Pyx_PyObject_IsTrue(PyObject*);
static CYTHON_INLINE int __Pyx_PyObject_IsTrueAndDecref(PyObject*);
static CYTHON_INLINE PyObject* __Pyx_PyNumber_IntOrLong(PyObject* x);
#define __Pyx_PySequence_Tuple(obj)\
    (likely(PyTuple_CheckExact(obj)) ? __Pyx_NewRef(obj) : PySequence_Tuple(obj))
static CYTHON_INLINE Py_ssize_t __Pyx_PyIndex_AsSsize_t(PyObject*);
static CYTHON_INLINE PyObject * __Pyx_PyInt_FromSize_t(size_t);
#if CYTHON_ASSUME_SAFE_MACROS
#define __pyx_PyFloat_AsDouble(x) (PyFloat_CheckExact(x) ? PyFloat_AS_DOUBLE(x) : PyFloat_AsDouble(x))
#else
#define __pyx_PyFloat_AsDouble(x) PyFloat_AsDouble(x)
#endif
#define __pyx_PyFloat_AsFloat(x) ((float) __pyx_PyFloat_AsDouble(x))
#if PY_MAJOR_VERSION >= 3
#define __Pyx_PyNumber_Int(x) (PyLong_CheckExact(x) ? __Pyx_NewRef(x) : PyNumber_Long(x))
#else
#define __Pyx_PyNumber_Int(x) (PyInt_CheckExact(x) ? __Pyx_NewRef(x) : PyNumber_Int(x))
#endif
#define __Pyx_PyNumber_Float(x) (PyFloat_CheckExact(x) ? __Pyx_NewRef(x) : PyNumber_Float(x))
#if PY_MAJOR_VERSION < 3 && __PYX_DEFAULT_STRING_ENCODING_IS_ASCII
static int __Pyx_sys_getdefaultencoding_not_ascii;
static int __Pyx_init_sys_getdefaultencoding_params(void) {
    PyObject* sys;
    PyObject* default_encoding = NULL;
    PyObject* ascii_chars_u = NULL;
    PyObject* ascii_chars_b = NULL;
    const char* default_encoding_c;
    sys = PyImport_ImportModule("sys");
    if (!sys) goto bad;
    default_encoding = PyObject_CallMethod(sys, (char*) "getdefaultencoding", NULL);
    Py_DECREF(sys);
    if (!default_encoding) goto bad;
    default_encoding_c = PyBytes_AsString(default_encoding);
    if (!default_encoding_c) goto bad;
    if (strcmp(default_encoding_c, "ascii") == 0) {
        __Pyx_sys_getdefaultencoding_not_ascii = 0;
    } else {
        char ascii_chars[128];
        int c;
        for (c = 0; c < 128; c++) {
            ascii_chars[c] = c;
        }
        __Pyx_sys_getdefaultencoding_not_ascii = 1;
        ascii_chars_u = PyUnicode_DecodeASCII(ascii_chars, 128, NULL);
        if (!ascii_chars_u) goto bad;
        ascii_chars_b = PyUnicode_AsEncodedString(ascii_chars_u, default_encoding_c, NULL);
        if (!ascii_chars_b || !PyBytes_Check(ascii_chars_b) || memcmp(ascii_chars, PyBytes_AS_STRING(ascii_chars_b), 128) != 0) {
            PyErr_Format(
                PyExc_ValueError,
                "This module compiled with c_string_encoding=ascii, but default encoding '%.200s' is not a superset of ascii.",
                default_encoding_c);
            goto bad;
        }
        Py_DECREF(ascii_chars_u);
        Py_DECREF(ascii_chars_b);
    }
    Py_DECREF(default_encoding);
    return 0;
bad:
    Py_XDECREF(default_encoding);
    Py_XDECREF(ascii_chars_u);
    Py_XDECREF(ascii_chars_b);
    return -1;
}
#endif
#if __PYX_DEFAULT_STRING_ENCODING_IS_DEFAULT && PY_MAJOR_VERSION >= 3
#define __Pyx_PyUnicode_FromStringAndSize(c_str, size) PyUnicode_DecodeUTF8(c_str, size, NULL)
#else
#define __Pyx_PyUnicode_FromStringAndSize(c_str, size) PyUnicode_Decode(c_str, size, __PYX_DEFAULT_STRING_ENCODING, NULL)
#if __PYX_DEFAULT_STRING_ENCODING_IS_DEFAULT
static char* __PYX_DEFAULT_STRING_ENCODING;
static int __Pyx_init_sys_getdefaultencoding_params(void) {
    PyObject* sys;
    PyObject* default_encoding = NULL;
    char* default_encoding_c;
    sys = PyImport_ImportModule("sys");
    if (!sys) goto bad;
    default_encoding = PyObject_CallMethod(sys, (char*) (const char*) "getdefaultencoding", NULL);
    Py_DECREF(sys);
    if (!default_encoding) goto bad;
    default_encoding_c = PyBytes_AsString(default_encoding);
    if (!default_encoding_c) goto bad;
    __PYX_DEFAULT_STRING_ENCODING = (char*) malloc(strlen(default_encoding_c) + 1);
    if (!__PYX_DEFAULT_STRING_ENCODING) goto bad;
    strcpy(__PYX_DEFAULT_STRING_ENCODING, default_encoding_c);
    Py_DECREF(default_encoding);
    return 0;
bad:
    Py_XDECREF(default_encoding);
    return -1;
}
#endif
#endif


/* Test for GCC > 2.95 */
#if defined(__GNUC__)     && (__GNUC__ > 2 || (__GNUC__ == 2 && (__GNUC_MINOR__ > 95)))
  #define likely(x)   __builtin_expect(!!(x), 1)
  #define unlikely(x) __builtin_expect(!!(x), 0)
#else /* !__GNUC__ or GCC < 2.95 */
  #define likely(x)   (x)
  #define unlikely(x) (x)
#endif /* __GNUC__ */
static CYTHON_INLINE void __Pyx_pretend_to_initialize(void* ptr) { (void)ptr; }

static PyObject *__pyx_m = NULL;
static PyObject *__pyx_d;
static PyObject *__pyx_b;
static PyObject *__pyx_cython_runtime = NULL;
static PyObject *__pyx_empty_tuple;
static PyObject *__pyx_empty_bytes;
static PyObject *__pyx_empty_unicode;
static int __pyx_lineno;
static int __pyx_clineno = 0;
static const char * __pyx_cfilenm= __FILE__;
static const char *__pyx_filename;

/* Header.proto */
#if !defined(CYTHON_CCOMPLEX)
  #if defined(__cplusplus)
    #define CYTHON_CCOMPLEX 1
  #elif defined(_Complex_I)
    #define CYTHON_CCOMPLEX 1
  #else
    #define CYTHON_CCOMPLEX 0
  #endif
#endif
#if CYTHON_CCOMPLEX
  #ifdef __cplusplus
    #include <complex>
  #else
    #include <complex.h>
  #endif
#endif
#if CYTHON_CCOMPLEX && !defined(__cplusplus) && defined(__sun__) && defined(__GNUC__)
  #undef _Complex_I
  #define _Complex_I 1.0fj
#endif


static const char *__pyx_f[] = {
  "_rnaseq_utils.pyx",
  "stringsource",
  "array.pxd",
  "__init__.pxd",
  "type.pxd",
  "bool.pxd",
  "complex.pxd",
};
/* MemviewSliceStruct.proto */
struct __pyx_memoryview_obj;
typedef struct {
  struct __pyx_memoryview_obj *memview;
  char *data;
  Py_ssize_t shape[8];
  Py_ssize_t strides[8];
  Py_ssize_t suboffsets[8];
} __Pyx_memviewslice;
#define __Pyx_MemoryView_Len(m)  (m.shape[0])

/* Atomics.proto */
#include <pythread.h>
#ifndef CYTHON_ATOMICS
    #define CYTHON_ATOMICS 1
#endif
#define __pyx_atomic_int_type int
#if CYTHON_ATOMICS && __GNUC__ >= 4 && (__GNUC_MINOR__ > 1 ||\
                    (__GNUC_MINOR__ == 1 && __GNUC_PATCHLEVEL >= 2)) &&\
                    !defined(__i386__)
    #define __pyx_atomic_incr_aligned(value, lock) __sync_fetch_and_add(value, 1)
    #define __pyx_atomic_decr_aligned(value, lock) __sync_fetch_and_sub(value, 1)
    #ifdef __PYX_DEBUG_ATOMICS
        #warning "Using GNU atomics"
    #endif
#elif CYTHON_ATOMICS && defined(_MSC_VER) && 0
    #include <Windows.h>
    #undef __pyx_atomic_int_type
    #define __pyx_atomic_int_type LONG
    #define __pyx_atomic_incr_aligned(value, lock) InterlockedIncrement(value)
    #define __pyx_atomic_decr_aligned(value, lock) InterlockedDecrement(value)
    #ifdef __PYX_DEBUG_ATOMICS
        #pragma message ("Using MSVC atomics")
    #endif
#elif CYTHON_ATOMICS && (defined(__ICC) || defined(__INTEL_COMPILER)) && 0
    #define __pyx_atomic_incr_aligned(value, lock) _InterlockedIncrement(value)
    #define __pyx_atomic_decr_aligned(value, lock) _InterlockedDecrement(value)
    #ifdef __PYX_DEBUG_ATOMICS
        #warning "Using Intel atomics"
    #endif
#else
    #undef CYTHON_ATOMICS
    #define CYTHON_ATOMICS 0
    #ifdef __PYX_DEBUG_ATOMICS
        #warning "Not using atomics"
    #endif
#endif
typedef volatile __pyx_atomic_int_type __pyx_atomic_int;
#if CYTHON_ATOMICS
    #define __pyx_add_acquisition_count(memview)\
             __pyx_atomic_incr_aligned(__pyx_get_slice_count_pointer(memview), memview->lock)
    #define __pyx_sub_acquisition_count(memview)\
            __pyx_atomic_decr_aligned(__pyx_get_slice_count_pointer(memview), memview->lock)
#else
    #define __pyx_add_acquisition_count(memview)\
            __pyx_add_acquisition_count_locked(__pyx_get_slice_count_pointer(memview), memview->lock)
    #define __pyx_sub_acquisition_count(memview)\
            __pyx_sub_acquisition_count_locked(__pyx_get_slice_count_pointer(memview), memview->lock)
#endif

/* BufferFormatStructs.proto */
#define IS_UNSIGNED(type) (((type) -1) > 0)
struct __Pyx_StructField_;
#define __PYX_BUF_FLAGS_PACKED_STRUCT (1 << 0)
typedef struct {
  const char* name;
  struct __Pyx_StructField_* fields;
  size_t size;
  size_t arraysize[8];
  int ndim;
  char typegroup;
  char is_unsigned;
  int flags;
} __Pyx_TypeInfo;
typedef struct __Pyx_StructField_ {
  __Pyx_TypeInfo* type;
  const char* name;
  size_t offset;
} __Pyx_StructField;
typedef struct {
  __Pyx_StructField* field;
  size_t parent_offset;
} __Pyx_BufFmt_StackElem;
typedef struct {
  __Pyx_StructField root;
  __Pyx_BufFmt_StackElem* head;
  size_t fmt_offset;
  size_t new_count, enc_count;
  size_t struct_alignment;
  int is_complex;
  char enc_type;
  char new_packmode;
  char enc_packmode;
  char is_valid_array;
} __Pyx_BufFmt_Context;

/* ForceInitThreads.proto */
#ifndef __PYX_FORCE_INIT_THREADS
  #define __PYX_FORCE_INIT_THREADS 0
#endif

/* NoFastGil.proto */
#define __Pyx_PyGILState_Ensure PyGILState_Ensure
#define __Pyx_PyGILState_Release PyGILState_Release
#define __Pyx_FastGIL_Remember()
#define __Pyx_FastGIL_Forget()
#define __Pyx_FastGilFuncInit()


/* "../../../../.conda/envs/bookend_env/lib/python3.7/site-packages/Cython/Includes/numpy/__init__.pxd":776
 * # in Cython to enable them only on the right systems.
 * 
 * ctypedef npy_int8       int8_t             # <<<<<<<<<<<<<<
 * ctypedef npy_int16      int16_t
 * ctypedef npy_int32      int32_t
 */
typedef npy_int8 __pyx_t_5numpy_int8_t;

/* "../../../../.conda/envs/bookend_env/lib/python3.7/site-packages/Cython/Includes/numpy/__init__.pxd":777
 * 
 * ctypedef npy_int8       int8_t
 * ctypedef npy_int16      int16_t             # <<<<<<<<<<<<<<
 * ctypedef npy_int32      int32_t
 * ctypedef npy_int64      int64_t
 */
typedef npy_int16 __pyx_t_5numpy_int16_t;

/* "../../../../.conda/envs/bookend_env/lib/python3.7/site-packages/Cython/Includes/numpy/__init__.pxd":778
 * ctypedef npy_int8       int8_t
 * ctypedef npy_int16      int16_t
 * ctypedef npy_int32      int32_t             # <<<<<<<<<<<<<<
 * ctypedef npy_int64      int64_t
 * #ctypedef npy_int96      int96_t
 */
typedef npy_int32 __pyx_t_5numpy_int32_t;

/* "../../../../.conda/envs/bookend_env/lib/python3.7/site-packages/Cython/Includes/numpy/__init__.pxd":779
 * ctypedef npy_int16      int16_t
 * ctypedef npy_int32      int32_t
 * ctypedef npy_int64      int64_t             # <<<<<<<<<<<<<<
 * #ctypedef npy_int96      int96_t
 * #ctypedef npy_int128     int128_t
 */
typedef npy_int64 __pyx_t_5numpy_int64_t;

/* "../../../../.conda/envs/bookend_env/lib/python3.7/site-packages/Cython/Includes/numpy/__init__.pxd":783
 * #ctypedef npy_int128     int128_t
 * 
 * ctypedef npy_uint8      uint8_t             # <<<<<<<<<<<<<<
 * ctypedef npy_uint16     uint16_t
 * ctypedef npy_uint32     uint32_t
 */
typedef npy_uint8 __pyx_t_5numpy_uint8_t;

/* "../../../../.conda/envs/bookend_env/lib/python3.7/site-packages/Cython/Includes/numpy/__init__.pxd":784
 * 
 * ctypedef npy_uint8      uint8_t
 * ctypedef npy_uint16     uint16_t             # <<<<<<<<<<<<<<
 * ctypedef npy_uint32     uint32_t
 * ctypedef npy_uint64     uint64_t
 */
typedef npy_uint16 __pyx_t_5numpy_uint16_t;

/* "../../../../.conda/envs/bookend_env/lib/python3.7/site-packages/Cython/Includes/numpy/__init__.pxd":785
 * ctypedef npy_uint8      uint8_t
 * ctypedef npy_uint16     uint16_t
 * ctypedef npy_uint32     uint32_t             # <<<<<<<<<<<<<<
 * ctypedef npy_uint64     uint64_t
 * #ctypedef npy_uint96     uint96_t
 */
typedef npy_uint32 __pyx_t_5numpy_uint32_t;

/* "../../../../.conda/envs/bookend_env/lib/python3.7/site-packages/Cython/Includes/numpy/__init__.pxd":786
 * ctypedef npy_uint16     uint16_t
 * ctypedef npy_uint32     uint32_t
 * ctypedef npy_uint64     uint64_t             # <<<<<<<<<<<<<<
 * #ctypedef npy_uint96     uint96_t
 * #ctypedef npy_uint128    uint128_t
 */
typedef npy_uint64 __pyx_t_5numpy_uint64_t;

/* "../../../../.conda/envs/bookend_env/lib/python3.7/site-packages/Cython/Includes/numpy/__init__.pxd":790
 * #ctypedef npy_uint128    uint128_t
 * 
 * ctypedef npy_float32    float32_t             # <<<<<<<<<<<<<<
 * ctypedef npy_float64    float64_t
 * #ctypedef npy_float80    float80_t
 */
typedef npy_float32 __pyx_t_5numpy_float32_t;

/* "../../../../.conda/envs/bookend_env/lib/python3.7/site-packages/Cython/Includes/numpy/__init__.pxd":791
 * 
 * ctypedef npy_float32    float32_t
 * ctypedef npy_float64    float64_t             # <<<<<<<<<<<<<<
 * #ctypedef npy_float80    float80_t
 * #ctypedef npy_float128   float128_t
 */
typedef npy_float64 __pyx_t_5numpy_float64_t;

/* "../../../../.conda/envs/bookend_env/lib/python3.7/site-packages/Cython/Includes/numpy/__init__.pxd":800
 * # The int types are mapped a bit surprising --
 * # numpy.int corresponds to 'l' and numpy.long to 'q'
 * ctypedef npy_long       int_t             # <<<<<<<<<<<<<<
 * ctypedef npy_longlong   long_t
 * ctypedef npy_longlong   longlong_t
 */
typedef npy_long __pyx_t_5numpy_int_t;

/* "../../../../.conda/envs/bookend_env/lib/python3.7/site-packages/Cython/Includes/numpy/__init__.pxd":801
 * # numpy.int corresponds to 'l' and numpy.long to 'q'
 * ctypedef npy_long       int_t
 * ctypedef npy_longlong   long_t             # <<<<<<<<<<<<<<
 * ctypedef npy_longlong   longlong_t
 * 
 */
typedef npy_longlong __pyx_t_5numpy_long_t;

/* "../../../../.conda/envs/bookend_env/lib/python3.7/site-packages/Cython/Includes/numpy/__init__.pxd":802
 * ctypedef npy_long       int_t
 * ctypedef npy_longlong   long_t
 * ctypedef npy_longlong   longlong_t             # <<<<<<<<<<<<<<
 * 
 * ctypedef npy_ulong      uint_t
 */
typedef npy_longlong __pyx_t_5numpy_longlong_t;

/* "../../../../.conda/envs/bookend_env/lib/python3.7/site-packages/Cython/Includes/numpy/__init__.pxd":804
 * ctypedef npy_longlong   longlong_t
 * 
 * ctypedef npy_ulong      uint_t             # <<<<<<<<<<<<<<
 * ctypedef npy_ulonglong  ulong_t
 * ctypedef npy_ulonglong  ulonglong_t
 */
typedef npy_ulong __pyx_t_5numpy_uint_t;

/* "../../../../.conda/envs/bookend_env/lib/python3.7/site-packages/Cython/Includes/numpy/__init__.pxd":805
 * 
 * ctypedef npy_ulong      uint_t
 * ctypedef npy_ulonglong  ulong_t             # <<<<<<<<<<<<<<
 * ctypedef npy_ulonglong  ulonglong_t
 * 
 */
typedef npy_ulonglong __pyx_t_5numpy_ulong_t;

/* "../../../../.conda/envs/bookend_env/lib/python3.7/site-packages/Cython/Includes/numpy/__init__.pxd":806
 * ctypedef npy_ulong      uint_t
 * ctypedef npy_ulonglong  ulong_t
 * ctypedef npy_ulonglong  ulonglong_t             # <<<<<<<<<<<<<<
 * 
 * ctypedef npy_intp       intp_t
 */
typedef npy_ulonglong __pyx_t_5numpy_ulonglong_t;

/* "../../../../.conda/envs/bookend_env/lib/python3.7/site-packages/Cython/Includes/numpy/__init__.pxd":808
 * ctypedef npy_ulonglong  ulonglong_t
 * 
 * ctypedef npy_intp       intp_t             # <<<<<<<<<<<<<<
 * ctypedef npy_uintp      uintp_t
 * 
 */
typedef npy_intp __pyx_t_5numpy_intp_t;

/* "../../../../.conda/envs/bookend_env/lib/python3.7/site-packages/Cython/Includes/numpy/__init__.pxd":809
 * 
 * ctypedef npy_intp       intp_t
 * ctypedef npy_uintp      uintp_t             # <<<<<<<<<<<<<<
 * 
 * ctypedef npy_double     float_t
 */
typedef npy_uintp __pyx_t_5numpy_uintp_t;

/* "../../../../.conda/envs/bookend_env/lib/python3.7/site-packages/Cython/Includes/numpy/__init__.pxd":811
 * ctypedef npy_uintp      uintp_t
 * 
 * ctypedef npy_double     float_t             # <<<<<<<<<<<<<<
 * ctypedef npy_double     double_t
 * ctypedef npy_longdouble longdouble_t
 */
typedef npy_double __pyx_t_5numpy_float_t;

/* "../../../../.conda/envs/bookend_env/lib/python3.7/site-packages/Cython/Includes/numpy/__init__.pxd":812
 * 
 * ctypedef npy_double     float_t
 * ctypedef npy_double     double_t             # <<<<<<<<<<<<<<
 * ctypedef npy_longdouble longdouble_t
 * 
 */
typedef npy_double __pyx_t_5numpy_double_t;

/* "../../../../.conda/envs/bookend_env/lib/python3.7/site-packages/Cython/Includes/numpy/__init__.pxd":813
 * ctypedef npy_double     float_t
 * ctypedef npy_double     double_t
 * ctypedef npy_longdouble longdouble_t             # <<<<<<<<<<<<<<
 * 
 * ctypedef npy_cfloat      cfloat_t
 */
typedef npy_longdouble __pyx_t_5numpy_longdouble_t;

/* "_rnaseq_utils.pyx":12
 * from ast import literal_eval
 * import copy
 * ctypedef unsigned char uint8             # <<<<<<<<<<<<<<
 * ctypedef np.float32_t float32
 * 
 */
typedef unsigned char __pyx_t_13_rnaseq_utils_uint8;

/* "_rnaseq_utils.pyx":13
 * import copy
 * ctypedef unsigned char uint8
 * ctypedef np.float32_t float32             # <<<<<<<<<<<<<<
 * 
 * ##############################################
 */
typedef __pyx_t_5numpy_float32_t __pyx_t_13_rnaseq_utils_float32;
/* Declarations.proto */
#if CYTHON_CCOMPLEX
  #ifdef __cplusplus
    typedef ::std::complex< float > __pyx_t_float_complex;
  #else
    typedef float _Complex __pyx_t_float_complex;
  #endif
#else
    typedef struct { float real, imag; } __pyx_t_float_complex;
#endif
static CYTHON_INLINE __pyx_t_float_complex __pyx_t_float_complex_from_parts(float, float);

/* Declarations.proto */
#if CYTHON_CCOMPLEX
  #ifdef __cplusplus
    typedef ::std::complex< double > __pyx_t_double_complex;
  #else
    typedef double _Complex __pyx_t_double_complex;
  #endif
#else
    typedef struct { double real, imag; } __pyx_t_double_complex;
#endif
static CYTHON_INLINE __pyx_t_double_complex __pyx_t_double_complex_from_parts(double, double);


/*--- Type declarations ---*/
#ifndef _ARRAYARRAY_H
struct arrayobject;
typedef struct arrayobject arrayobject;
#endif
struct __pyx_obj_13_rnaseq_utils_RNAseqMapping;
struct __pyx_obj_13_rnaseq_utils_RNAseqDataset;
struct __pyx_obj_13_rnaseq_utils_AnnotationObject;
struct __pyx_obj_13_rnaseq_utils_AnnotationDataset;
struct __pyx_obj_13_rnaseq_utils_BAMobject;
struct __pyx_obj_13_rnaseq_utils_BranchpointArray;
struct __pyx_obj_13_rnaseq_utils_BranchPoint;
struct __pyx_obj_13_rnaseq_utils_StartPoint;
struct __pyx_obj_13_rnaseq_utils_EndPoint;
struct __pyx_obj_13_rnaseq_utils_DonorPoint;
struct __pyx_obj_13_rnaseq_utils_AcceptorPoint;
struct __pyx_obj_13_rnaseq_utils_OrderedArray;
struct __pyx_obj_13_rnaseq_utils___pyx_scope_struct__generate_loci;
struct __pyx_obj_13_rnaseq_utils___pyx_scope_struct_1_array_to_blocks;
struct __pyx_obj_13_rnaseq_utils___pyx_scope_struct_2_split_chunk;
struct __pyx_obj_13_rnaseq_utils___pyx_scope_struct_3_parse_MD_string;
struct __pyx_obj_13_rnaseq_utils___pyx_scope_struct_4_read_generator;
struct __pyx_array_obj;
struct __pyx_MemviewEnum_obj;
struct __pyx_memoryview_obj;
struct __pyx_memoryviewslice_obj;

/* "../../../../.conda/envs/bookend_env/lib/python3.7/site-packages/Cython/Includes/numpy/__init__.pxd":815
 * ctypedef npy_longdouble longdouble_t
 * 
 * ctypedef npy_cfloat      cfloat_t             # <<<<<<<<<<<<<<
 * ctypedef npy_cdouble     cdouble_t
 * ctypedef npy_clongdouble clongdouble_t
 */
typedef npy_cfloat __pyx_t_5numpy_cfloat_t;

/* "../../../../.conda/envs/bookend_env/lib/python3.7/site-packages/Cython/Includes/numpy/__init__.pxd":816
 * 
 * ctypedef npy_cfloat      cfloat_t
 * ctypedef npy_cdouble     cdouble_t             # <<<<<<<<<<<<<<
 * ctypedef npy_clongdouble clongdouble_t
 * 
 */
typedef npy_cdouble __pyx_t_5numpy_cdouble_t;

/* "../../../../.conda/envs/bookend_env/lib/python3.7/site-packages/Cython/Includes/numpy/__init__.pxd":817
 * ctypedef npy_cfloat      cfloat_t
 * ctypedef npy_cdouble     cdouble_t
 * ctypedef npy_clongdouble clongdouble_t             # <<<<<<<<<<<<<<
 * 
 * ctypedef npy_cdouble     complex_t
 */
typedef npy_clongdouble __pyx_t_5numpy_clongdouble_t;

/* "../../../../.conda/envs/bookend_env/lib/python3.7/site-packages/Cython/Includes/numpy/__init__.pxd":819
 * ctypedef npy_clongdouble clongdouble_t
 * 
 * ctypedef npy_cdouble     complex_t             # <<<<<<<<<<<<<<
 * 
 * cdef inline object PyArray_MultiIterNew1(a):
 */
typedef npy_cdouble __pyx_t_5numpy_complex_t;
struct __pyx_ctuple_int__and_int;
typedef struct __pyx_ctuple_int__and_int __pyx_ctuple_int__and_int;
struct __pyx_opt_args_13_rnaseq_utils_13RNAseqMapping_splice_match;
struct __pyx_opt_args_13_rnaseq_utils_13RNAseqMapping_is_compatible;
struct __pyx_opt_args_13_rnaseq_utils_13RNAseqMapping_write_as_elr;
struct __pyx_opt_args_13_rnaseq_utils_13RNAseqMapping_write_as_bed;
struct __pyx_opt_args_13_rnaseq_utils_13RNAseqDataset_add_read_from_BED;
struct __pyx_opt_args_13_rnaseq_utils_13RNAseqDataset_add_read_from_BAM;
struct __pyx_opt_args_13_rnaseq_utils_13RNAseqDataset_pop_read;
struct __pyx_opt_args_13_rnaseq_utils_parse_BED_line;
struct __pyx_opt_args_13_rnaseq_utils_parse_SAM_CIGAR;
struct __pyx_opt_args_13_rnaseq_utils_is_homopolymer;
struct __pyx_ctuple_int__and_int__and_int__and_int;
typedef struct __pyx_ctuple_int__and_int__and_int__and_int __pyx_ctuple_int__and_int__and_int__and_int;
struct __pyx_opt_args_13_rnaseq_utils_parse_tag;
struct __pyx_ctuple_int__and_int__and_int;
typedef struct __pyx_ctuple_int__and_int__and_int __pyx_ctuple_int__and_int__and_int;
struct __pyx_opt_args_13_rnaseq_utils_16BranchpointArray_add_endpoint;
struct __pyx_opt_args_13_rnaseq_utils_12OrderedArray_get_insert_pos;
struct __pyx_opt_args_13_rnaseq_utils_get_gaps;
struct __pyx_ctuple_float__and_int__and_int__and_int;
typedef struct __pyx_ctuple_float__and_int__and_int__and_int __pyx_ctuple_float__and_int__and_int__and_int;
struct __pyx_ctuple_int__and_float;
typedef struct __pyx_ctuple_int__and_float __pyx_ctuple_int__and_float;

/* "_rnaseq_utils.pyx":24
 *     cdef public bint s_tag, e_tag, capped, complete, is_reference
 *     cdef public dict attributes
 *     cdef public (int, int) span             # <<<<<<<<<<<<<<
 *     cdef public float weight, coverage
 *     def __init__(self, input_data, attributes = None):
 */
struct __pyx_ctuple_int__and_int {
  int f0;
  int f1;
};

/* "_rnaseq_utils.pyx":146
 *         return False
 * 
 *     cpdef bint splice_match(self, RNAseqMapping other, bint ignore_ends=True):             # <<<<<<<<<<<<<<
 *         """Returns bool of whether self and other ranges match perfectly.
 *         Discards 5' and 3' terminus if ignore_ends."""
 */
struct __pyx_opt_args_13_rnaseq_utils_13RNAseqMapping_splice_match {
  int __pyx_n;
  int ignore_ends;
};

/* "_rnaseq_utils.pyx":183
 *         return False
 * 
 *     cpdef bint is_compatible(self, RNAseqMapping other, bint ignore_ends=False, bint ignore_source=False):             # <<<<<<<<<<<<<<
 *         """Self and other contain no attributes that demonstrate they could
 *         not be subsequences of a common longer molecule."""
 */
struct __pyx_opt_args_13_rnaseq_utils_13RNAseqMapping_is_compatible {
  int __pyx_n;
  int ignore_ends;
  int ignore_source;
};

/* "_rnaseq_utils.pyx":309
 *         return(''.join([startchar]+[gapchar if i else '..' for i in self.splice]+[endchar]))
 * 
 *     cpdef write_as_elr(self, as_string=True, record_artifacts=False):             # <<<<<<<<<<<<<<
 *         """Returns a string that represents the ReadObject
 *         in the end-labeled read (ELR) format"""
 */
struct __pyx_opt_args_13_rnaseq_utils_13RNAseqMapping_write_as_elr {
  int __pyx_n;
  PyObject *as_string;
  PyObject *record_artifacts;
};

/* "_rnaseq_utils.pyx":331
 *             return elr_line
 * 
 *     cpdef write_as_bed(self, chrom_array, source_array, as_string=True, score_column='weight', record_artifacts=False, name_attr=None):             # <<<<<<<<<<<<<<
 *         """Returns a string that represents the ReadObject
 *         in a 15-column BED format"""
 */
struct __pyx_opt_args_13_rnaseq_utils_13RNAseqMapping_write_as_bed {
  int __pyx_n;
  PyObject *as_string;
  PyObject *score_column;
  PyObject *record_artifacts;
  PyObject *name_attr;
};

/* "_rnaseq_utils.pyx":522
 *             self.chrom_index += 1
 * 
 *     cpdef add_read_from_BED(self, bed_line, source_string=None, s_tag=False, e_tag=False, capped=False, gaps_are_junctions=False):             # <<<<<<<<<<<<<<
 *         cdef RNAseqMapping new_read
 *         input_data = parse_BED_line(bed_line, self.chrom_dict, self.source_dict, source_string, s_tag, e_tag, capped, gaps_are_junctions)
 */
struct __pyx_opt_args_13_rnaseq_utils_13RNAseqDataset_add_read_from_BED {
  int __pyx_n;
  PyObject *source_string;
  PyObject *s_tag;
  PyObject *e_tag;
  PyObject *capped;
  PyObject *gaps_are_junctions;
};

/* "_rnaseq_utils.pyx":558
 *         self.read_list.append(new_read)
 * 
 *     cpdef add_read_from_BAM(self, bam_lines, bint ignore_ends=False, bint secondary=False):             # <<<<<<<<<<<<<<
 *         cdef list new_read_list
 *         cdef RNAseqMapping read
 */
struct __pyx_opt_args_13_rnaseq_utils_13RNAseqDataset_add_read_from_BAM {
  int __pyx_n;
  int ignore_ends;
  int secondary;
};

/* "_rnaseq_utils.pyx":583
 *         self.read_list += new_read_list
 * 
 *     cpdef pop_read(self, read_format='elr', as_string=True):             # <<<<<<<<<<<<<<
 *         """Remove the last read added to the stack and write it in 'format'.
 *         """
 */
struct __pyx_opt_args_13_rnaseq_utils_13RNAseqDataset_pop_read {
  int __pyx_n;
  PyObject *read_format;
  PyObject *as_string;
};

/* "_rnaseq_utils.pyx":1126
 *     return ELdata(chrom, source, strand, ranges, splice, s_tag, e_tag, capped, weight)
 * 
 * cdef parse_BED_line(bed_line, chrom_dict, source_dict, source_string=None, s_tag=False, e_tag=False, capped=False, gaps_are_junctions=False):             # <<<<<<<<<<<<<<
 *     """Parses one line of a 12- or 15-column BED file into an ELdata namedtuple.
 *     Examples:
 */
struct __pyx_opt_args_13_rnaseq_utils_parse_BED_line {
  int __pyx_n;
  PyObject *source_string;
  PyObject *s_tag;
  PyObject *e_tag;
  PyObject *capped;
  PyObject *gaps_are_junctions;
};

/* "_rnaseq_utils.pyx":1374
 * 
 * 
 * cpdef parse_SAM_CIGAR(int pos, list cigartuples, str mdstring, float error_rate=0.1):             # <<<<<<<<<<<<<<
 *     """Converts the po and pysam-parsed CIGAR object of a SAM file to
 *     an array of 0-indexed open (left,right) blocks as ranges and gaps.
 */
struct __pyx_opt_args_13_rnaseq_utils_parse_SAM_CIGAR {
  int __pyx_n;
  float error_rate;
};

/* "_rnaseq_utils.pyx":1463
 * 
 * 
 * cdef bint is_homopolymer(str string, float threshold=0.8):             # <<<<<<<<<<<<<<
 *     """Returns whether a single character composes > threshold
 *     of a string."""
 */
struct __pyx_opt_args_13_rnaseq_utils_is_homopolymer {
  int __pyx_n;
  float threshold;
};

/* "_rnaseq_utils.pyx":1489
 * 
 * 
 * cdef (bint, bint, int, int) parse_tag(str string, str tagsplit='_TAG='):             # <<<<<<<<<<<<<<
 *     """Updates readtype based on a tag present in the ID string"""
 *     cdef int e_len, s_len
 */
struct __pyx_ctuple_int__and_int__and_int__and_int {
  int f0;
  int f1;
  int f2;
  int f3;
};
struct __pyx_opt_args_13_rnaseq_utils_parse_tag {
  int __pyx_n;
  PyObject *tagsplit;
};

/* "_rnaseq_utils.pyx":1800
 *         return splice
 * 
 *     cdef (bint, bint, bint) filter_labels_by_softclip_length(self, bint s_tag, bint e_tag, bint capped, bint fiveprime, bint threeprime, int strand, int head, int tail):             # <<<<<<<<<<<<<<
 *         """Determines whether the s_tag, e_tag and capped parameters
 *         should be removed an alignment that has softclipping on its edges."""
 */
struct __pyx_ctuple_int__and_int__and_int {
  int f0;
  int f1;
  int f2;
};

/* "_rnaseq_utils.pyx":2327
 *                 return pos - self.leftmost
 * 
 *     cpdef void add_endpoint(self, BranchPoint BP, force=True):             # <<<<<<<<<<<<<<
 *         """Add an S/E BranchPoint to the bp dict of OrderedArrays.
 *         If at least one same-type branchpoint is in span, merge BP
 */
struct __pyx_opt_args_13_rnaseq_utils_16BranchpointArray_add_endpoint {
  int __pyx_n;
  PyObject *force;
};

/* "_rnaseq_utils.pyx":2534
 *         return new_OA
 * 
 *     cdef int get_insert_pos(self, search_value, init=None):             # <<<<<<<<<<<<<<
 *         """Runs a binary search, returns an insert position where 'search_value'
 *         fits in array. Assumes array to be sorted. In the case of a tie,
 */
struct __pyx_opt_args_13_rnaseq_utils_12OrderedArray_get_insert_pos {
  int __pyx_n;
  PyObject *init;
};

/* "_rnaseq_utils.pyx":2616
 * 
 * 
 * cpdef list get_gaps(np.ndarray[float, ndim=1] array, int maxgap, threshold = float(1)):             # <<<<<<<<<<<<<<
 *     """Returns True if no gap longer than maxgap in the array falls below the threshold"""
 *     cdef Py_ssize_t i, l
 */
struct __pyx_opt_args_13_rnaseq_utils_get_gaps {
  int __pyx_n;
  PyObject *threshold;
};

/* "_rnaseq_utils.pyx":1948
 *             char strand
 *             list s_rank, e_rank, rank_sort, merged_plus, merged_minus, to_remove, donors, acceptors, gaps, gap_branchpoints
 *             (float, int, int, int) ranking             # <<<<<<<<<<<<<<
 *             (int, float) item
 *             (int, int) block
 */
struct __pyx_ctuple_float__and_int__and_int__and_int {
  float f0;
  int f1;
  int f2;
  int f3;
};

/* "_rnaseq_utils.pyx":1949
 *             list s_rank, e_rank, rank_sort, merged_plus, merged_minus, to_remove, donors, acceptors, gaps, gap_branchpoints
 *             (float, int, int, int) ranking
 *             (int, float) item             # <<<<<<<<<<<<<<
 *             (int, int) block
 *             dict lookup, end_counts, Sp, Sm, Cp, Cm, Ep, Em, Dp, Dm, Ap, Am, S, E, bp_dict
 */
struct __pyx_ctuple_int__and_float {
  int f0;
  float f1;
};

/* "_rnaseq_utils.pyx":19
 * ##############################################
 * ELdata = namedtuple('ELdata', 'chrom source strand ranges splice s_tag e_tag capped weight')
 * cdef class RNAseqMapping():             # <<<<<<<<<<<<<<
 *     cdef public int chrom, source, strand, s_len, e_len
 *     cdef public list ranges, splice
 */
struct __pyx_obj_13_rnaseq_utils_RNAseqMapping {
  PyObject_HEAD
  struct __pyx_vtabstruct_13_rnaseq_utils_RNAseqMapping *__pyx_vtab;
  int chrom;
  int source;
  int strand;
  int s_len;
  int e_len;
  PyObject *ranges;
  PyObject *splice;
  int s_tag;
  int e_tag;
  int capped;
  int complete;
  int is_reference;
  PyObject *attributes;
  __pyx_ctuple_int__and_int span;
  float weight;
  float coverage;
};


/* "_rnaseq_utils.pyx":457
 * }
 * 
 * cdef class RNAseqDataset():             # <<<<<<<<<<<<<<
 *     cdef public list read_list, chrom_array, source_array, chrom_lengths
 *     cdef public int chrom_index, source_index
 */
struct __pyx_obj_13_rnaseq_utils_RNAseqDataset {
  PyObject_HEAD
  struct __pyx_vtabstruct_13_rnaseq_utils_RNAseqDataset *__pyx_vtab;
  PyObject *read_list;
  PyObject *chrom_array;
  PyObject *source_array;
  PyObject *chrom_lengths;
  int chrom_index;
  int source_index;
  PyObject *chrom_dict;
  PyObject *source_dict;
  PyObject *config;
  PyObject *genome;
  PyObject *label_tally;
  int s_tag;
  int e_tag;
  int capped;
  int stranded;
  int ignore_ends;
  PyObject *start_seq;
  PyObject *end_seq;
  int minlen;
  int minlen_strict;
  int minlen_loose;
  float mismatch_rate;
  arrayobject *start_array;
  arrayobject *end_array;
};


/* "_rnaseq_utils.pyx":628
 * }
 * 
 * cdef class AnnotationObject:             # <<<<<<<<<<<<<<
 *     cdef public dict attributes
 *     cdef public bint keep, parent
 */
struct __pyx_obj_13_rnaseq_utils_AnnotationObject {
  PyObject_HEAD
  struct __pyx_vtabstruct_13_rnaseq_utils_AnnotationObject *__pyx_vtab;
  PyObject *attributes;
  int keep;
  int parent;
  PyObject *format;
  PyObject *gene_id;
  PyObject *transcript_id;
  PyObject *chrom;
  PyObject *source;
  PyObject *anno_type;
  int strand;
  __pyx_ctuple_int__and_int span;
  PyObject *fields;
};


/* "_rnaseq_utils.pyx":704
 * 
 * 
 * cdef class AnnotationDataset(RNAseqDataset):             # <<<<<<<<<<<<<<
 *     """Child of an RNAseqDataset. Parses a set of input annotations (GFF3/GTF/BED12/ELR).
 *     Has methods that allow these annotations to be merged together to
 */
struct __pyx_obj_13_rnaseq_utils_AnnotationDataset {
  struct __pyx_obj_13_rnaseq_utils_RNAseqDataset __pyx_base;
  PyObject *annotations;
  PyObject *gtf_config;
  PyObject *gff_config;
  PyObject *generator;
  int number_of_assemblies;
  int counter;
  int min_reps;
  int confidence;
  float cap_percent;
  int verbose;
};


/* "_rnaseq_utils.pyx":1520
 *     return s_tag, e_tag, s_len, e_len
 * 
 * cdef class BAMobject:             # <<<<<<<<<<<<<<
 *     cdef readonly RNAseqDataset dataset
 *     cdef readonly list input_lines
 */
struct __pyx_obj_13_rnaseq_utils_BAMobject {
  PyObject_HEAD
  struct __pyx_vtabstruct_13_rnaseq_utils_BAMobject *__pyx_vtab;
  struct __pyx_obj_13_rnaseq_utils_RNAseqDataset *dataset;
  PyObject *input_lines;
  int ignore_ends;
  int secondary;
};


/* "_rnaseq_utils.pyx":1927
 * #############################################################################################
 * 
 * cdef class BranchpointArray:             # <<<<<<<<<<<<<<
 *     cdef readonly dict S_plus, S_minus, E_plus, E_minus, J_plus, J_minus
 *     cdef readonly int leftmost, rightmost, extend, end_extend, length, min_overhang
 */
struct __pyx_obj_13_rnaseq_utils_BranchpointArray {
  PyObject_HEAD
  struct __pyx_vtabstruct_13_rnaseq_utils_BranchpointArray *__pyx_vtab;
  PyObject *S_plus;
  PyObject *S_minus;
  PyObject *E_plus;
  PyObject *E_minus;
  PyObject *J_plus;
  PyObject *J_minus;
  int leftmost;
  int rightmost;
  int extend;
  int end_extend;
  int length;
  int min_overhang;
  PyObject *branchpoints;
  float weight;
  float threshold;
  float cap_percent;
  float minimum_proportion;
  PyArrayObject *depth;
  struct __pyx_obj_13_rnaseq_utils_OrderedArray *bp_plus;
  struct __pyx_obj_13_rnaseq_utils_OrderedArray *bp_minus;
  int infer_starts;
  int infer_ends;
  int use_attributes;
};


/* "_rnaseq_utils.pyx":2411
 * 
 * bp_typeorder = {'N':-1, 'E':0, 'A':1, 'D':2, 'S':3} # Sort order for branchpoint types
 * cdef class BranchPoint:             # <<<<<<<<<<<<<<
 *     """Represents a reference point for a Start, End, Donor, or Acceptor site."""
 *     cdef readonly str branchtype
 */
struct __pyx_obj_13_rnaseq_utils_BranchPoint {
  PyObject_HEAD
  struct __pyx_vtabstruct_13_rnaseq_utils_BranchPoint *__pyx_vtab;
  PyObject *branchtype;
  char strand;
  int pos;
  int index;
  int left;
  int right;
  float weight;
  __pyx_ctuple_int__and_int comparator;
};


/* "_rnaseq_utils.pyx":2448
 * 
 * 
 * cdef class StartPoint(BranchPoint):             # <<<<<<<<<<<<<<
 *     """Represents a transcript start site"""
 *     cdef public int extend
 */
struct __pyx_obj_13_rnaseq_utils_StartPoint {
  struct __pyx_obj_13_rnaseq_utils_BranchPoint __pyx_base;
  int extend;
  PyObject *span;
  float capped;
};


/* "_rnaseq_utils.pyx":2471
 *         self.span = range(self.left-self.extend, self.right+self.extend+1)
 * 
 * cdef class EndPoint(BranchPoint):             # <<<<<<<<<<<<<<
 *     """Represents a transcript termination site"""
 *     cdef public int extend
 */
struct __pyx_obj_13_rnaseq_utils_EndPoint {
  struct __pyx_obj_13_rnaseq_utils_BranchPoint __pyx_base;
  int extend;
  PyObject *span;
};


/* "_rnaseq_utils.pyx":2487
 *         self.span = range(self.left-self.extend, self.right+self.extend+1)
 * 
 * cdef class DonorPoint(BranchPoint):             # <<<<<<<<<<<<<<
 *     """Represents a transcript start site"""
 *     def __init__(self, strand, pos, weight):
 */
struct __pyx_obj_13_rnaseq_utils_DonorPoint {
  struct __pyx_obj_13_rnaseq_utils_BranchPoint __pyx_base;
};


/* "_rnaseq_utils.pyx":2492
 *         BranchPoint.__init__(self, 'D', strand, pos, weight)
 * 
 * cdef class AcceptorPoint(BranchPoint):             # <<<<<<<<<<<<<<
 *     """Represents a transcript start site"""
 *     def __init__(self, strand, pos, weight):
 */
struct __pyx_obj_13_rnaseq_utils_AcceptorPoint {
  struct __pyx_obj_13_rnaseq_utils_BranchPoint __pyx_base;
};


/* "_rnaseq_utils.pyx":2497
 *         BranchPoint.__init__(self, 'A', strand, pos, weight)
 * 
 * cdef class OrderedArray:             # <<<<<<<<<<<<<<
 *     """Maintains an array in sort order and a lookup dict for the location of each
 *     item that was added."""
 */
struct __pyx_obj_13_rnaseq_utils_OrderedArray {
  PyObject_HEAD
  struct __pyx_vtabstruct_13_rnaseq_utils_OrderedArray *__pyx_vtab;
  int n;
  PyObject *ordered_array;
};


/* "_rnaseq_utils.pyx":923
 *         return mapping_object
 * 
 *     def generate_loci(self):             # <<<<<<<<<<<<<<
 *         """Yields a contiguous chunk of all annotation objects as a list
 *         by interleaving all sorted annotations together."""
 */
struct __pyx_obj_13_rnaseq_utils___pyx_scope_struct__generate_loci {
  PyObject_HEAD
  PyObject *__pyx_v_chrom;
  PyObject *__pyx_v_chrom_annotation_list;
  PyObject *__pyx_v_current_chunk;
  int __pyx_v_i;
  struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_item;
  PyObject *__pyx_v_k;
  int __pyx_v_left;
  Py_ssize_t __pyx_v_number_of_files;
  int __pyx_v_number_of_items;
  long __pyx_v_rightmost;
  struct __pyx_obj_13_rnaseq_utils_AnnotationDataset *__pyx_v_self;
  PyObject *__pyx_t_0;
  Py_ssize_t __pyx_t_1;
  int __pyx_t_2;
  int __pyx_t_3;
  int __pyx_t_4;
};


/* "_rnaseq_utils.pyx":964
 * }
 * 
 * def array_to_blocks(list arr):             # <<<<<<<<<<<<<<
 *     """Breaks an array into a collections of (start,end) INCLUSIVE doubles
 *     that define the coordinates of all contiguous blocks in the array"""
 */
struct __pyx_obj_13_rnaseq_utils___pyx_scope_struct_1_array_to_blocks {
  PyObject_HEAD
  PyObject *__pyx_v_arr;
  int __pyx_v_block_end;
  int __pyx_v_block_start;
  PyObject *__pyx_v_clean_array;
  int __pyx_9genexpr24__pyx_v_i;
  int __pyx_v_i;
  PyObject *__pyx_t_0;
  Py_ssize_t __pyx_t_1;
};


/* "_rnaseq_utils.pyx":1247
 *     return coverage
 * 
 * def split_chunk(list reads, float minimum_proportion, int max_gap):             # <<<<<<<<<<<<<<
 *     """Takes a list of reads and cuts it at the first span of
 *     > max_gap nucleotides at a coverage < minimum_proportion * max_cov
 */
struct __pyx_obj_13_rnaseq_utils___pyx_scope_struct_2_split_chunk {
  PyObject_HEAD
  __Pyx_memviewslice __pyx_v_COV;
  Py_ssize_t __pyx_v_array_length;
  float __pyx_v_c;
  PyArrayObject *__pyx_v_coverage;
  int __pyx_v_gap;
  Py_ssize_t __pyx_v_i;
  int __pyx_v_index;
  PyArrayObject *__pyx_v_is_gap;
  Py_ssize_t __pyx_v_l;
  int __pyx_v_last_index;
  long __pyx_v_leading_edge;
  int __pyx_v_leftmost;
  float __pyx_v_max_cov;
  int __pyx_v_max_gap;
  float __pyx_v_minimum_proportion;
  int __pyx_v_number_of_reads;
  Py_ssize_t __pyx_v_r;
  struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_read;
  PyObject *__pyx_v_reads;
  int __pyx_v_rightmost;
  __pyx_ctuple_int__and_int __pyx_v_span;
  int __pyx_v_was_gap;
  int __pyx_t_0;
  int __pyx_t_1;
  Py_ssize_t __pyx_t_2;
  int __pyx_t_3;
};


/* "_rnaseq_utils.pyx":1351
 *     return strand
 * 
 * def parse_MD_string(str mdstring):             # <<<<<<<<<<<<<<
 *     """Creates a generator object to yield the elements
 *     in an MD:Z tag from the SAM format. The elements are either
 */
struct __pyx_obj_13_rnaseq_utils___pyx_scope_struct_3_parse_MD_string {
  PyObject_HEAD
  PyObject *__pyx_v_c;
  PyObject *__pyx_v_current;
  int __pyx_v_is_digit;
  PyObject *__pyx_v_mdstring;
  int __pyx_v_was_digit;
  PyObject *__pyx_t_0;
  Py_ssize_t __pyx_t_1;
  Py_ssize_t __pyx_t_2;
  void *__pyx_t_3;
  int __pyx_t_4;
  Py_ssize_t __pyx_t_5;
};


/* "_rnaseq_utils.pyx":1875
 * 
 * 
 * def read_generator(fileconn, RNAseqDataset dataset, str file_type, int max_gap):             # <<<<<<<<<<<<<<
 *     """Yields a contiguous chunk of reads from the input file
 *     separated on either side by a gaps > max_gap"""
 */
struct __pyx_obj_13_rnaseq_utils___pyx_scope_struct_4_read_generator {
  PyObject_HEAD
  PyObject *__pyx_v_add_read;
  struct __pyx_obj_13_rnaseq_utils_RNAseqDataset *__pyx_v_dataset;
  PyObject *__pyx_v_file_type;
  PyObject *__pyx_v_fileconn;
  PyObject *__pyx_v_header_line;
  int __pyx_v_last_chrom;
  struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_last_read;
  PyObject *__pyx_v_line;
  int __pyx_v_max_gap;
  int __pyx_v_rightmost;
  PyObject *__pyx_t_0;
  Py_ssize_t __pyx_t_1;
  PyObject *(*__pyx_t_2)(PyObject *);
};


/* "View.MemoryView":105
 * 
 * @cname("__pyx_array")
 * cdef class array:             # <<<<<<<<<<<<<<
 * 
 *     cdef:
 */
struct __pyx_array_obj {
  PyObject_HEAD
  struct __pyx_vtabstruct_array *__pyx_vtab;
  char *data;
  Py_ssize_t len;
  char *format;
  int ndim;
  Py_ssize_t *_shape;
  Py_ssize_t *_strides;
  Py_ssize_t itemsize;
  PyObject *mode;
  PyObject *_format;
  void (*callback_free_data)(void *);
  int free_data;
  int dtype_is_object;
};


/* "View.MemoryView":279
 * 
 * @cname('__pyx_MemviewEnum')
 * cdef class Enum(object):             # <<<<<<<<<<<<<<
 *     cdef object name
 *     def __init__(self, name):
 */
struct __pyx_MemviewEnum_obj {
  PyObject_HEAD
  PyObject *name;
};


/* "View.MemoryView":330
 * 
 * @cname('__pyx_memoryview')
 * cdef class memoryview(object):             # <<<<<<<<<<<<<<
 * 
 *     cdef object obj
 */
struct __pyx_memoryview_obj {
  PyObject_HEAD
  struct __pyx_vtabstruct_memoryview *__pyx_vtab;
  PyObject *obj;
  PyObject *_size;
  PyObject *_array_interface;
  PyThread_type_lock lock;
  __pyx_atomic_int acquisition_count[2];
  __pyx_atomic_int *acquisition_count_aligned_p;
  Py_buffer view;
  int flags;
  int dtype_is_object;
  __Pyx_TypeInfo *typeinfo;
};


/* "View.MemoryView":965
 * 
 * @cname('__pyx_memoryviewslice')
 * cdef class _memoryviewslice(memoryview):             # <<<<<<<<<<<<<<
 *     "Internal class for passing memoryview slices to Python"
 * 
 */
struct __pyx_memoryviewslice_obj {
  struct __pyx_memoryview_obj __pyx_base;
  __Pyx_memviewslice from_slice;
  PyObject *from_object;
  PyObject *(*to_object_func)(char *);
  int (*to_dtype_func)(char *, PyObject *);
};



/* "_rnaseq_utils.pyx":19
 * ##############################################
 * ELdata = namedtuple('ELdata', 'chrom source strand ranges splice s_tag e_tag capped weight')
 * cdef class RNAseqMapping():             # <<<<<<<<<<<<<<
 *     cdef public int chrom, source, strand, s_len, e_len
 *     cdef public list ranges, splice
 */

struct __pyx_vtabstruct_13_rnaseq_utils_RNAseqMapping {
  int (*left)(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *, int __pyx_skip_dispatch);
  int (*right)(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *, int __pyx_skip_dispatch);
  int (*get_length)(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *, int __pyx_skip_dispatch);
  PyObject *(*gaps)(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *, int __pyx_skip_dispatch);
  PyObject *(*junctions)(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *, int __pyx_skip_dispatch);
  int (*diff)(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *, PyObject *, int __pyx_skip_dispatch);
  int (*overlaps)(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *, struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *, int __pyx_skip_dispatch);
  __pyx_ctuple_int__and_int (*overlap_range)(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *, struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *, int __pyx_skip_dispatch);
  int (*ends_clash)(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *, struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *, int __pyx_skip_dispatch);
  int (*splice_match)(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *, struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *, int __pyx_skip_dispatch, struct __pyx_opt_args_13_rnaseq_utils_13RNAseqMapping_splice_match *__pyx_optional_args);
  int (*antisense_match)(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *, struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *, int, int __pyx_skip_dispatch);
  int (*sense_match)(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *, struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *, int, int __pyx_skip_dispatch);
  int (*is_compatible)(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *, struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *, int __pyx_skip_dispatch, struct __pyx_opt_args_13_rnaseq_utils_13RNAseqMapping_is_compatible *__pyx_optional_args);
  int (*is_identical)(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *, struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *, int __pyx_skip_dispatch);
  int (*merge)(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *, struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *, int __pyx_skip_dispatch);
  PyObject *(*write_as_elr)(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *, int __pyx_skip_dispatch, struct __pyx_opt_args_13_rnaseq_utils_13RNAseqMapping_write_as_elr *__pyx_optional_args);
  PyObject *(*write_as_bed)(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *, PyObject *, PyObject *, int __pyx_skip_dispatch, struct __pyx_opt_args_13_rnaseq_utils_13RNAseqMapping_write_as_bed *__pyx_optional_args);
};
static struct __pyx_vtabstruct_13_rnaseq_utils_RNAseqMapping *__pyx_vtabptr_13_rnaseq_utils_RNAseqMapping;


/* "_rnaseq_utils.pyx":457
 * }
 * 
 * cdef class RNAseqDataset():             # <<<<<<<<<<<<<<
 *     cdef public list read_list, chrom_array, source_array, chrom_lengths
 *     cdef public int chrom_index, source_index
 */

struct __pyx_vtabstruct_13_rnaseq_utils_RNAseqDataset {
  PyObject *(*add_source)(struct __pyx_obj_13_rnaseq_utils_RNAseqDataset *, PyObject *, int __pyx_skip_dispatch);
  PyObject *(*add_chrom)(struct __pyx_obj_13_rnaseq_utils_RNAseqDataset *, PyObject *, int __pyx_skip_dispatch);
  PyObject *(*add_read_from_BED)(struct __pyx_obj_13_rnaseq_utils_RNAseqDataset *, PyObject *, int __pyx_skip_dispatch, struct __pyx_opt_args_13_rnaseq_utils_13RNAseqDataset_add_read_from_BED *__pyx_optional_args);
  PyObject *(*add_read)(struct __pyx_obj_13_rnaseq_utils_RNAseqDataset *, PyObject *, int __pyx_skip_dispatch);
  PyObject *(*add_read_from_ELR)(struct __pyx_obj_13_rnaseq_utils_RNAseqDataset *, PyObject *, int __pyx_skip_dispatch);
  PyObject *(*add_read_from_BAM)(struct __pyx_obj_13_rnaseq_utils_RNAseqDataset *, PyObject *, int __pyx_skip_dispatch, struct __pyx_opt_args_13_rnaseq_utils_13RNAseqDataset_add_read_from_BAM *__pyx_optional_args);
  PyObject *(*pop_read)(struct __pyx_obj_13_rnaseq_utils_RNAseqDataset *, int __pyx_skip_dispatch, struct __pyx_opt_args_13_rnaseq_utils_13RNAseqDataset_pop_read *__pyx_optional_args);
  PyObject *(*dump_header)(struct __pyx_obj_13_rnaseq_utils_RNAseqDataset *, int __pyx_skip_dispatch);
};
static struct __pyx_vtabstruct_13_rnaseq_utils_RNAseqDataset *__pyx_vtabptr_13_rnaseq_utils_RNAseqDataset;


/* "_rnaseq_utils.pyx":628
 * }
 * 
 * cdef class AnnotationObject:             # <<<<<<<<<<<<<<
 *     cdef public dict attributes
 *     cdef public bint keep, parent
 */

struct __pyx_vtabstruct_13_rnaseq_utils_AnnotationObject {
  PyObject *(*parse_attributes)(struct __pyx_obj_13_rnaseq_utils_AnnotationObject *, PyObject *, PyObject *, int __pyx_skip_dispatch);
};
static struct __pyx_vtabstruct_13_rnaseq_utils_AnnotationObject *__pyx_vtabptr_13_rnaseq_utils_AnnotationObject;


/* "_rnaseq_utils.pyx":704
 * 
 * 
 * cdef class AnnotationDataset(RNAseqDataset):             # <<<<<<<<<<<<<<
 *     """Child of an RNAseqDataset. Parses a set of input annotations (GFF3/GTF/BED12/ELR).
 *     Has methods that allow these annotations to be merged together to
 */

struct __pyx_vtabstruct_13_rnaseq_utils_AnnotationDataset {
  struct __pyx_vtabstruct_13_rnaseq_utils_RNAseqDataset __pyx_base;
  PyObject *(*import_annotation)(struct __pyx_obj_13_rnaseq_utils_AnnotationDataset *, PyObject *, PyObject *, int __pyx_skip_dispatch);
  PyObject *(*get_transcript_fasta)(struct __pyx_obj_13_rnaseq_utils_AnnotationDataset *, struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *, int __pyx_skip_dispatch);
  struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *(*parse_bed_line)(struct __pyx_obj_13_rnaseq_utils_AnnotationDataset *, PyObject *);
  struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *(*parse_elr_line)(struct __pyx_obj_13_rnaseq_utils_AnnotationDataset *, PyObject *, PyObject *, PyObject *);
  struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *(*anno_to_mapping_object)(struct __pyx_obj_13_rnaseq_utils_AnnotationDataset *, struct __pyx_obj_13_rnaseq_utils_AnnotationObject *, PyObject *, int, int __pyx_skip_dispatch);
};
static struct __pyx_vtabstruct_13_rnaseq_utils_AnnotationDataset *__pyx_vtabptr_13_rnaseq_utils_AnnotationDataset;


/* "_rnaseq_utils.pyx":1520
 *     return s_tag, e_tag, s_len, e_len
 * 
 * cdef class BAMobject:             # <<<<<<<<<<<<<<
 *     cdef readonly RNAseqDataset dataset
 *     cdef readonly list input_lines
 */

struct __pyx_vtabstruct_13_rnaseq_utils_BAMobject {
  PyObject *(*generate_read)(struct __pyx_obj_13_rnaseq_utils_BAMobject *, int __pyx_skip_dispatch);
  int (*get_mapping_number)(struct __pyx_obj_13_rnaseq_utils_BAMobject *);
  __pyx_ctuple_int__and_int (*determine_strand)(struct __pyx_obj_13_rnaseq_utils_BAMobject *, PyObject *, int);
  int (*should_skip)(struct __pyx_obj_13_rnaseq_utils_BAMobject *, PyObject *);
  int (*fails_stringent_filters)(struct __pyx_obj_13_rnaseq_utils_BAMobject *, int, int, int, int, int);
  int (*get_alignment_strand)(struct __pyx_obj_13_rnaseq_utils_BAMobject *, PyObject *);
  PyObject *(*get_splice_info)(struct __pyx_obj_13_rnaseq_utils_BAMobject *, PyObject *, PyObject *, PyObject *, int);
  __pyx_ctuple_int__and_int__and_int (*filter_labels_by_softclip_length)(struct __pyx_obj_13_rnaseq_utils_BAMobject *, int, int, int, int, int, int, int, int);
  int (*untemplated_upstream_g)(struct __pyx_obj_13_rnaseq_utils_BAMobject *, int, int, int, PyObject *, PyObject *, PyObject *);
  void (*restore_terminal_mismatches)(struct __pyx_obj_13_rnaseq_utils_BAMobject *, int, int, int, PyObject *);
  int (*matches_masking_sequence)(struct __pyx_obj_13_rnaseq_utils_BAMobject *, PyObject *, int, int, PyObject *, int);
};
static struct __pyx_vtabstruct_13_rnaseq_utils_BAMobject *__pyx_vtabptr_13_rnaseq_utils_BAMobject;


/* "_rnaseq_utils.pyx":1927
 * #############################################################################################
 * 
 * cdef class BranchpointArray:             # <<<<<<<<<<<<<<
 *     cdef readonly dict S_plus, S_minus, E_plus, E_minus, J_plus, J_minus
 *     cdef readonly int leftmost, rightmost, extend, end_extend, length, min_overhang
 */

struct __pyx_vtabstruct_13_rnaseq_utils_BranchpointArray {
  PyObject *(*bp_from_counter)(struct __pyx_obj_13_rnaseq_utils_BranchpointArray *, PyObject *, PyObject *, char, int __pyx_skip_dispatch);
  int (*distance_from_edge)(struct __pyx_obj_13_rnaseq_utils_BranchpointArray *, int, char, PyObject *, int __pyx_skip_dispatch);
  void (*add_endpoint)(struct __pyx_obj_13_rnaseq_utils_BranchpointArray *, struct __pyx_obj_13_rnaseq_utils_BranchPoint *, int __pyx_skip_dispatch, struct __pyx_opt_args_13_rnaseq_utils_16BranchpointArray_add_endpoint *__pyx_optional_args);
  PyObject *(*infer_unknown_branchpoints)(struct __pyx_obj_13_rnaseq_utils_BranchpointArray *, PyObject *, int __pyx_skip_dispatch);
  void (*remove_branchpoint)(struct __pyx_obj_13_rnaseq_utils_BranchpointArray *, PyObject *, int, int __pyx_skip_dispatch);
};
static struct __pyx_vtabstruct_13_rnaseq_utils_BranchpointArray *__pyx_vtabptr_13_rnaseq_utils_BranchpointArray;


/* "_rnaseq_utils.pyx":2411
 * 
 * bp_typeorder = {'N':-1, 'E':0, 'A':1, 'D':2, 'S':3} # Sort order for branchpoint types
 * cdef class BranchPoint:             # <<<<<<<<<<<<<<
 *     """Represents a reference point for a Start, End, Donor, or Acceptor site."""
 *     cdef readonly str branchtype
 */

struct __pyx_vtabstruct_13_rnaseq_utils_BranchPoint {
  float (*percent_capped)(struct __pyx_obj_13_rnaseq_utils_BranchPoint *, int __pyx_skip_dispatch);
};
static struct __pyx_vtabstruct_13_rnaseq_utils_BranchPoint *__pyx_vtabptr_13_rnaseq_utils_BranchPoint;


/* "_rnaseq_utils.pyx":2448
 * 
 * 
 * cdef class StartPoint(BranchPoint):             # <<<<<<<<<<<<<<
 *     """Represents a transcript start site"""
 *     cdef public int extend
 */

struct __pyx_vtabstruct_13_rnaseq_utils_StartPoint {
  struct __pyx_vtabstruct_13_rnaseq_utils_BranchPoint __pyx_base;
};
static struct __pyx_vtabstruct_13_rnaseq_utils_StartPoint *__pyx_vtabptr_13_rnaseq_utils_StartPoint;


/* "_rnaseq_utils.pyx":2471
 *         self.span = range(self.left-self.extend, self.right+self.extend+1)
 * 
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 */

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};
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/* "_rnaseq_utils.pyx":2487
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 *     """Represents a transcript start site"""
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 */

struct __pyx_vtabstruct_13_rnaseq_utils_DonorPoint {
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/* "_rnaseq_utils.pyx":2492
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struct __pyx_vtabstruct_13_rnaseq_utils_AcceptorPoint {
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/* "_rnaseq_utils.pyx":2497
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/* CallUnboundCMethod2.proto */
static PyObject* __Pyx__CallUnboundCMethod2(__Pyx_CachedCFunction* cfunc, PyObject* self, PyObject* arg1, PyObject* arg2);
#if CYTHON_COMPILING_IN_CPYTHON && PY_VERSION_HEX >= 0x030600B1
static CYTHON_INLINE PyObject *__Pyx_CallUnboundCMethod2(__Pyx_CachedCFunction *cfunc, PyObject *self, PyObject *arg1, PyObject *arg2);
#else
#define __Pyx_CallUnboundCMethod2(cfunc, self, arg1, arg2)  __Pyx__CallUnboundCMethod2(cfunc, self, arg1, arg2)
#endif

/* PyIntBinop.proto */
#if !CYTHON_COMPILING_IN_PYPY
static PyObject* __Pyx_PyInt_SubtractObjC(PyObject *op1, PyObject *op2, long intval, int inplace, int zerodivision_check);
#else
#define __Pyx_PyInt_SubtractObjC(op1, op2, intval, inplace, zerodivision_check)\
    (inplace ? PyNumber_InPlaceSubtract(op1, op2) : PyNumber_Subtract(op1, op2))
#endif

/* PyUnicode_Substring.proto */
static CYTHON_INLINE PyObject* __Pyx_PyUnicode_Substring(
            PyObject* text, Py_ssize_t start, Py_ssize_t stop);

/* PyObjectGetMethod.proto */
static int __Pyx_PyObject_GetMethod(PyObject *obj, PyObject *name, PyObject **method);

/* PyObjectCallMethod0.proto */
static PyObject* __Pyx_PyObject_CallMethod0(PyObject* obj, PyObject* method_name);

/* RaiseNoneIterError.proto */
static CYTHON_INLINE void __Pyx_RaiseNoneNotIterableError(void);

/* UnpackTupleError.proto */
static void __Pyx_UnpackTupleError(PyObject *, Py_ssize_t index);

/* UnpackTuple2.proto */
#define __Pyx_unpack_tuple2(tuple, value1, value2, is_tuple, has_known_size, decref_tuple)\
    (likely(is_tuple || PyTuple_Check(tuple)) ?\
        (likely(has_known_size || PyTuple_GET_SIZE(tuple) == 2) ?\
            __Pyx_unpack_tuple2_exact(tuple, value1, value2, decref_tuple) :\
            (__Pyx_UnpackTupleError(tuple, 2), -1)) :\
        __Pyx_unpack_tuple2_generic(tuple, value1, value2, has_known_size, decref_tuple))
static CYTHON_INLINE int __Pyx_unpack_tuple2_exact(
    PyObject* tuple, PyObject** value1, PyObject** value2, int decref_tuple);
static int __Pyx_unpack_tuple2_generic(
    PyObject* tuple, PyObject** value1, PyObject** value2, int has_known_size, int decref_tuple);

/* dict_iter.proto */
static CYTHON_INLINE PyObject* __Pyx_dict_iterator(PyObject* dict, int is_dict, PyObject* method_name,
                                                   Py_ssize_t* p_orig_length, int* p_is_dict);
static CYTHON_INLINE int __Pyx_dict_iter_next(PyObject* dict_or_iter, Py_ssize_t orig_length, Py_ssize_t* ppos,
                                              PyObject** pkey, PyObject** pvalue, PyObject** pitem, int is_dict);

/* PyObjectFormatSimple.proto */
#if CYTHON_COMPILING_IN_PYPY
    #define __Pyx_PyObject_FormatSimple(s, f) (\
        likely(PyUnicode_CheckExact(s)) ? (Py_INCREF(s), s) :\
        PyObject_Format(s, f))
#elif PY_MAJOR_VERSION < 3
    #define __Pyx_PyObject_FormatSimple(s, f) (\
        likely(PyUnicode_CheckExact(s)) ? (Py_INCREF(s), s) :\
        likely(PyString_CheckExact(s)) ? PyUnicode_FromEncodedObject(s, NULL, "strict") :\
        PyObject_Format(s, f))
#elif CYTHON_USE_TYPE_SLOTS
    #define __Pyx_PyObject_FormatSimple(s, f) (\
        likely(PyUnicode_CheckExact(s)) ? (Py_INCREF(s), s) :\
        likely(PyLong_CheckExact(s)) ? PyLong_Type.tp_str(s) :\
        likely(PyFloat_CheckExact(s)) ? PyFloat_Type.tp_str(s) :\
        PyObject_Format(s, f))
#else
    #define __Pyx_PyObject_FormatSimple(s, f) (\
        likely(PyUnicode_CheckExact(s)) ? (Py_INCREF(s), s) :\
        PyObject_Format(s, f))
#endif

/* JoinPyUnicode.proto */
static PyObject* __Pyx_PyUnicode_Join(PyObject* value_tuple, Py_ssize_t value_count, Py_ssize_t result_ulength,
                                      Py_UCS4 max_char);

/* PyErrExceptionMatches.proto */
#if CYTHON_FAST_THREAD_STATE
#define __Pyx_PyErr_ExceptionMatches(err) __Pyx_PyErr_ExceptionMatchesInState(__pyx_tstate, err)
static CYTHON_INLINE int __Pyx_PyErr_ExceptionMatchesInState(PyThreadState* tstate, PyObject* err);
#else
#define __Pyx_PyErr_ExceptionMatches(err)  PyErr_ExceptionMatches(err)
#endif

/* GetAttr.proto */
static CYTHON_INLINE PyObject *__Pyx_GetAttr(PyObject *, PyObject *);

/* GetAttr3.proto */
static CYTHON_INLINE PyObject *__Pyx_GetAttr3(PyObject *, PyObject *, PyObject *);

/* ExtTypeTest.proto */
static CYTHON_INLINE int __Pyx_TypeTest(PyObject *obj, PyTypeObject *type);

/* py_dict_keys.proto */
static CYTHON_INLINE PyObject* __Pyx_PyDict_Keys(PyObject* d);

/* CallUnboundCMethod0.proto */
static PyObject* __Pyx__CallUnboundCMethod0(__Pyx_CachedCFunction* cfunc, PyObject* self);
#if CYTHON_COMPILING_IN_CPYTHON
#define __Pyx_CallUnboundCMethod0(cfunc, self)\
    (likely((cfunc)->func) ?\
        (likely((cfunc)->flag == METH_NOARGS) ?  (*((cfunc)->func))(self, NULL) :\
         (PY_VERSION_HEX >= 0x030600B1 && likely((cfunc)->flag == METH_FASTCALL) ?\
            (PY_VERSION_HEX >= 0x030700A0 ?\
                (*(__Pyx_PyCFunctionFast)(void*)(PyCFunction)(cfunc)->func)(self, &__pyx_empty_tuple, 0) :\
                (*(__Pyx_PyCFunctionFastWithKeywords)(void*)(PyCFunction)(cfunc)->func)(self, &__pyx_empty_tuple, 0, NULL)) :\
          (PY_VERSION_HEX >= 0x030700A0 && (cfunc)->flag == (METH_FASTCALL | METH_KEYWORDS) ?\
            (*(__Pyx_PyCFunctionFastWithKeywords)(void*)(PyCFunction)(cfunc)->func)(self, &__pyx_empty_tuple, 0, NULL) :\
            (likely((cfunc)->flag == (METH_VARARGS | METH_KEYWORDS)) ?  ((*(PyCFunctionWithKeywords)(void*)(PyCFunction)(cfunc)->func)(self, __pyx_empty_tuple, NULL)) :\
               ((cfunc)->flag == METH_VARARGS ?  (*((cfunc)->func))(self, __pyx_empty_tuple) :\
               __Pyx__CallUnboundCMethod0(cfunc, self)))))) :\
        __Pyx__CallUnboundCMethod0(cfunc, self))
#else
#define __Pyx_CallUnboundCMethod0(cfunc, self)  __Pyx__CallUnboundCMethod0(cfunc, self)
#endif

/* PyDictContains.proto */
static CYTHON_INLINE int __Pyx_PyDict_ContainsTF(PyObject* item, PyObject* dict, int eq) {
    int result = PyDict_Contains(dict, item);
    return unlikely(result < 0) ? result : (result == (eq == Py_EQ));
}

/* ListAppend.proto */
#if CYTHON_USE_PYLIST_INTERNALS && CYTHON_ASSUME_SAFE_MACROS
static CYTHON_INLINE int __Pyx_PyList_Append(PyObject* list, PyObject* x) {
    PyListObject* L = (PyListObject*) list;
    Py_ssize_t len = Py_SIZE(list);
    if (likely(L->allocated > len) & likely(len > (L->allocated >> 1))) {
        Py_INCREF(x);
        PyList_SET_ITEM(list, len, x);
        Py_SIZE(list) = len+1;
        return 0;
    }
    return PyList_Append(list, x);
}
#else
#define __Pyx_PyList_Append(L,x) PyList_Append(L,x)
#endif

/* SetItemInt.proto */
#define __Pyx_SetItemInt(o, i, v, type, is_signed, to_py_func, is_list, wraparound, boundscheck)\
    (__Pyx_fits_Py_ssize_t(i, type, is_signed) ?\
    __Pyx_SetItemInt_Fast(o, (Py_ssize_t)i, v, is_list, wraparound, boundscheck) :\
    (is_list ? (PyErr_SetString(PyExc_IndexError, "list assignment index out of range"), -1) :\
               __Pyx_SetItemInt_Generic(o, to_py_func(i), v)))
static int __Pyx_SetItemInt_Generic(PyObject *o, PyObject *j, PyObject *v);
static CYTHON_INLINE int __Pyx_SetItemInt_Fast(PyObject *o, Py_ssize_t i, PyObject *v,
                                               int is_list, int wraparound, int boundscheck);

/* pop.proto */
static CYTHON_INLINE PyObject* __Pyx__PyObject_Pop(PyObject* L);
#if CYTHON_USE_PYLIST_INTERNALS && CYTHON_ASSUME_SAFE_MACROS
static CYTHON_INLINE PyObject* __Pyx_PyList_Pop(PyObject* L);
#define __Pyx_PyObject_Pop(L) (likely(PyList_CheckExact(L)) ?\
    __Pyx_PyList_Pop(L) : __Pyx__PyObject_Pop(L))
#else
#define __Pyx_PyList_Pop(L)  __Pyx__PyObject_Pop(L)
#define __Pyx_PyObject_Pop(L)  __Pyx__PyObject_Pop(L)
#endif

/* SliceObject.proto */
static CYTHON_INLINE PyObject* __Pyx_PyObject_GetSlice(
        PyObject* obj, Py_ssize_t cstart, Py_ssize_t cstop,
        PyObject** py_start, PyObject** py_stop, PyObject** py_slice,
        int has_cstart, int has_cstop, int wraparound);

/* pyfrozenset_new.proto */
static CYTHON_INLINE PyObject* __Pyx_PyFrozenSet_New(PyObject* it);

/* PySetContains.proto */
static CYTHON_INLINE int __Pyx_PySet_ContainsTF(PyObject* key, PyObject* set, int eq);

/* None.proto */
static CYTHON_INLINE void __Pyx_RaiseUnboundLocalError(const char *varname);

/* PyObjectCallMethod1.proto */
static PyObject* __Pyx_PyObject_CallMethod1(PyObject* obj, PyObject* method_name, PyObject* arg);

/* append.proto */
static CYTHON_INLINE int __Pyx_PyObject_Append(PyObject* L, PyObject* x);

/* RaiseException.proto */
static void __Pyx_Raise(PyObject *type, PyObject *value, PyObject *tb, PyObject *cause);

/* SliceTupleAndList.proto */
#if CYTHON_COMPILING_IN_CPYTHON
static CYTHON_INLINE PyObject* __Pyx_PyList_GetSlice(PyObject* src, Py_ssize_t start, Py_ssize_t stop);
static CYTHON_INLINE PyObject* __Pyx_PyTuple_GetSlice(PyObject* src, Py_ssize_t start, Py_ssize_t stop);
#else
#define __Pyx_PyList_GetSlice(seq, start, stop)   PySequence_GetSlice(seq, start, stop)
#define __Pyx_PyTuple_GetSlice(seq, start, stop)  PySequence_GetSlice(seq, start, stop)
#endif

/* unicode_iter.proto */
static CYTHON_INLINE int __Pyx_init_unicode_iteration(
    PyObject* ustring, Py_ssize_t *length, void** data, int *kind);

/* GetItemIntUnicode.proto */
#define __Pyx_GetItemInt_Unicode(o, i, type, is_signed, to_py_func, is_list, wraparound, boundscheck)\
    (__Pyx_fits_Py_ssize_t(i, type, is_signed) ?\
    __Pyx_GetItemInt_Unicode_Fast(o, (Py_ssize_t)i, wraparound, boundscheck) :\
    (PyErr_SetString(PyExc_IndexError, "string index out of range"), (Py_UCS4)-1))
static CYTHON_INLINE Py_UCS4 __Pyx_GetItemInt_Unicode_Fast(PyObject* ustring, Py_ssize_t i,
                                                           int wraparound, int boundscheck);

/* GetTopmostException.proto */
#if CYTHON_USE_EXC_INFO_STACK
static _PyErr_StackItem * __Pyx_PyErr_GetTopmostException(PyThreadState *tstate);
#endif

/* SaveResetException.proto */
#if CYTHON_FAST_THREAD_STATE
#define __Pyx_ExceptionSave(type, value, tb)  __Pyx__ExceptionSave(__pyx_tstate, type, value, tb)
static CYTHON_INLINE void __Pyx__ExceptionSave(PyThreadState *tstate, PyObject **type, PyObject **value, PyObject **tb);
#define __Pyx_ExceptionReset(type, value, tb)  __Pyx__ExceptionReset(__pyx_tstate, type, value, tb)
static CYTHON_INLINE void __Pyx__ExceptionReset(PyThreadState *tstate, PyObject *type, PyObject *value, PyObject *tb);
#else
#define __Pyx_ExceptionSave(type, value, tb)   PyErr_GetExcInfo(type, value, tb)
#define __Pyx_ExceptionReset(type, value, tb)  PyErr_SetExcInfo(type, value, tb)
#endif

/* GetException.proto */
#if CYTHON_FAST_THREAD_STATE
#define __Pyx_GetException(type, value, tb)  __Pyx__GetException(__pyx_tstate, type, value, tb)
static int __Pyx__GetException(PyThreadState *tstate, PyObject **type, PyObject **value, PyObject **tb);
#else
static int __Pyx_GetException(PyObject **type, PyObject **value, PyObject **tb);
#endif

/* BufferIndexError.proto */
static void __Pyx_RaiseBufferIndexError(int axis);

/* SliceObject.proto */
#define __Pyx_PyObject_DelSlice(obj, cstart, cstop, py_start, py_stop, py_slice, has_cstart, has_cstop, wraparound)\
    __Pyx_PyObject_SetSlice(obj, (PyObject*)NULL, cstart, cstop, py_start, py_stop, py_slice, has_cstart, has_cstop, wraparound)
static CYTHON_INLINE int __Pyx_PyObject_SetSlice(
        PyObject* obj, PyObject* value, Py_ssize_t cstart, Py_ssize_t cstop,
        PyObject** py_start, PyObject** py_stop, PyObject** py_slice,
        int has_cstart, int has_cstop, int wraparound);

/* MemviewSliceInit.proto */
#define __Pyx_BUF_MAX_NDIMS %(BUF_MAX_NDIMS)d
#define __Pyx_MEMVIEW_DIRECT   1
#define __Pyx_MEMVIEW_PTR      2
#define __Pyx_MEMVIEW_FULL     4
#define __Pyx_MEMVIEW_CONTIG   8
#define __Pyx_MEMVIEW_STRIDED  16
#define __Pyx_MEMVIEW_FOLLOW   32
#define __Pyx_IS_C_CONTIG 1
#define __Pyx_IS_F_CONTIG 2
static int __Pyx_init_memviewslice(
                struct __pyx_memoryview_obj *memview,
                int ndim,
                __Pyx_memviewslice *memviewslice,
                int memview_is_new_reference);
static CYTHON_INLINE int __pyx_add_acquisition_count_locked(
    __pyx_atomic_int *acquisition_count, PyThread_type_lock lock);
static CYTHON_INLINE int __pyx_sub_acquisition_count_locked(
    __pyx_atomic_int *acquisition_count, PyThread_type_lock lock);
#define __pyx_get_slice_count_pointer(memview) (memview->acquisition_count_aligned_p)
#define __pyx_get_slice_count(memview) (*__pyx_get_slice_count_pointer(memview))
#define __PYX_INC_MEMVIEW(slice, have_gil) __Pyx_INC_MEMVIEW(slice, have_gil, __LINE__)
#define __PYX_XDEC_MEMVIEW(slice, have_gil) __Pyx_XDEC_MEMVIEW(slice, have_gil, __LINE__)
static CYTHON_INLINE void __Pyx_INC_MEMVIEW(__Pyx_memviewslice *, int, int);
static CYTHON_INLINE void __Pyx_XDEC_MEMVIEW(__Pyx_memviewslice *, int, int);

/* IterNext.proto */
#define __Pyx_PyIter_Next(obj) __Pyx_PyIter_Next2(obj, NULL)
static CYTHON_INLINE PyObject *__Pyx_PyIter_Next2(PyObject *, PyObject *);

/* DelItemInt.proto */
#define __Pyx_DelItemInt(o, i, type, is_signed, to_py_func, is_list, wraparound, boundscheck)\
    (__Pyx_fits_Py_ssize_t(i, type, is_signed) ?\
    __Pyx_DelItemInt_Fast(o, (Py_ssize_t)i, is_list, wraparound) :\
    (is_list ? (PyErr_SetString(PyExc_IndexError, "list assignment index out of range"), -1) :\
               __Pyx_DelItem_Generic(o, to_py_func(i))))
static int __Pyx_DelItem_Generic(PyObject *o, PyObject *j);
static CYTHON_INLINE int __Pyx_DelItemInt_Fast(PyObject *o, Py_ssize_t i,
                                               int is_list, int wraparound);

/* PyUnicodeContains.proto */
static CYTHON_INLINE int __Pyx_PyUnicode_ContainsTF(PyObject* substring, PyObject* text, int eq) {
    int result = PyUnicode_Contains(text, substring);
    return unlikely(result < 0) ? result : (result == (eq == Py_EQ));
}

/* PyIntCompare.proto */
static CYTHON_INLINE PyObject* __Pyx_PyInt_EqObjC(PyObject *op1, PyObject *op2, long intval, long inplace);

/* py_dict_values.proto */
static CYTHON_INLINE PyObject* __Pyx_PyDict_Values(PyObject* d);

/* None.proto */
static CYTHON_INLINE long __Pyx_div_long(long, long);

/* IsLittleEndian.proto */
static CYTHON_INLINE int __Pyx_Is_Little_Endian(void);

/* BufferFormatCheck.proto */
static const char* __Pyx_BufFmt_CheckString(__Pyx_BufFmt_Context* ctx, const char* ts);
static void __Pyx_BufFmt_Init(__Pyx_BufFmt_Context* ctx,
                              __Pyx_BufFmt_StackElem* stack,
                              __Pyx_TypeInfo* type);

/* BufferGetAndValidate.proto */
#define __Pyx_GetBufferAndValidate(buf, obj, dtype, flags, nd, cast, stack)\
    ((obj == Py_None || obj == NULL) ?\
    (__Pyx_ZeroBuffer(buf), 0) :\
    __Pyx__GetBufferAndValidate(buf, obj, dtype, flags, nd, cast, stack))
static int  __Pyx__GetBufferAndValidate(Py_buffer* buf, PyObject* obj,
    __Pyx_TypeInfo* dtype, int flags, int nd, int cast, __Pyx_BufFmt_StackElem* stack);
static void __Pyx_ZeroBuffer(Py_buffer* buf);
static CYTHON_INLINE void __Pyx_SafeReleaseBuffer(Py_buffer* info);
static Py_ssize_t __Pyx_minusones[] = { -1, -1, -1, -1, -1, -1, -1, -1 };
static Py_ssize_t __Pyx_zeros[] = { 0, 0, 0, 0, 0, 0, 0, 0 };

/* Import.proto */
static PyObject *__Pyx_Import(PyObject *name, PyObject *from_list, int level);

/* ImportFrom.proto */
static PyObject* __Pyx_ImportFrom(PyObject* module, PyObject* name);

/* HasAttr.proto */
static CYTHON_INLINE int __Pyx_HasAttr(PyObject *, PyObject *);

/* StrEquals.proto */
#if PY_MAJOR_VERSION >= 3
#define __Pyx_PyString_Equals __Pyx_PyUnicode_Equals
#else
#define __Pyx_PyString_Equals __Pyx_PyBytes_Equals
#endif

/* None.proto */
static CYTHON_INLINE Py_ssize_t __Pyx_div_Py_ssize_t(Py_ssize_t, Py_ssize_t);

/* UnaryNegOverflows.proto */
#define UNARY_NEG_WOULD_OVERFLOW(x)\
        (((x) < 0) & ((unsigned long)(x) == 0-(unsigned long)(x)))

static CYTHON_UNUSED int __pyx_array_getbuffer(PyObject *__pyx_v_self, Py_buffer *__pyx_v_info, int __pyx_v_flags); /*proto*/
static PyObject *__pyx_array_get_memview(struct __pyx_array_obj *); /*proto*/
/* decode_c_string_utf16.proto */
static CYTHON_INLINE PyObject *__Pyx_PyUnicode_DecodeUTF16(const char *s, Py_ssize_t size, const char *errors) {
    int byteorder = 0;
    return PyUnicode_DecodeUTF16(s, size, errors, &byteorder);
}
static CYTHON_INLINE PyObject *__Pyx_PyUnicode_DecodeUTF16LE(const char *s, Py_ssize_t size, const char *errors) {
    int byteorder = -1;
    return PyUnicode_DecodeUTF16(s, size, errors, &byteorder);
}
static CYTHON_INLINE PyObject *__Pyx_PyUnicode_DecodeUTF16BE(const char *s, Py_ssize_t size, const char *errors) {
    int byteorder = 1;
    return PyUnicode_DecodeUTF16(s, size, errors, &byteorder);
}

/* decode_c_string.proto */
static CYTHON_INLINE PyObject* __Pyx_decode_c_string(
         const char* cstring, Py_ssize_t start, Py_ssize_t stop,
         const char* encoding, const char* errors,
         PyObject* (*decode_func)(const char *s, Py_ssize_t size, const char *errors));

/* SwapException.proto */
#if CYTHON_FAST_THREAD_STATE
#define __Pyx_ExceptionSwap(type, value, tb)  __Pyx__ExceptionSwap(__pyx_tstate, type, value, tb)
static CYTHON_INLINE void __Pyx__ExceptionSwap(PyThreadState *tstate, PyObject **type, PyObject **value, PyObject **tb);
#else
static CYTHON_INLINE void __Pyx_ExceptionSwap(PyObject **type, PyObject **value, PyObject **tb);
#endif

/* FastTypeChecks.proto */
#if CYTHON_COMPILING_IN_CPYTHON
#define __Pyx_TypeCheck(obj, type) __Pyx_IsSubtype(Py_TYPE(obj), (PyTypeObject *)type)
static CYTHON_INLINE int __Pyx_IsSubtype(PyTypeObject *a, PyTypeObject *b);
static CYTHON_INLINE int __Pyx_PyErr_GivenExceptionMatches(PyObject *err, PyObject *type);
static CYTHON_INLINE int __Pyx_PyErr_GivenExceptionMatches2(PyObject *err, PyObject *type1, PyObject *type2);
#else
#define __Pyx_TypeCheck(obj, type) PyObject_TypeCheck(obj, (PyTypeObject *)type)
#define __Pyx_PyErr_GivenExceptionMatches(err, type) PyErr_GivenExceptionMatches(err, type)
#define __Pyx_PyErr_GivenExceptionMatches2(err, type1, type2) (PyErr_GivenExceptionMatches(err, type1) || PyErr_GivenExceptionMatches(err, type2))
#endif
#define __Pyx_PyException_Check(obj) __Pyx_TypeCheck(obj, PyExc_Exception)

static CYTHON_UNUSED int __pyx_memoryview_getbuffer(PyObject *__pyx_v_self, Py_buffer *__pyx_v_info, int __pyx_v_flags); /*proto*/
/* ListExtend.proto */
static CYTHON_INLINE int __Pyx_PyList_Extend(PyObject* L, PyObject* v) {
#if CYTHON_COMPILING_IN_CPYTHON
    PyObject* none = _PyList_Extend((PyListObject*)L, v);
    if (unlikely(!none))
        return -1;
    Py_DECREF(none);
    return 0;
#else
    return PyList_SetSlice(L, PY_SSIZE_T_MAX, PY_SSIZE_T_MAX, v);
#endif
}

/* CallNextTpTraverse.proto */
static int __Pyx_call_next_tp_traverse(PyObject* obj, visitproc v, void *a, traverseproc current_tp_traverse);

/* CallNextTpClear.proto */
static void __Pyx_call_next_tp_clear(PyObject* obj, inquiry current_tp_dealloc);

/* PyObject_GenericGetAttrNoDict.proto */
#if CYTHON_USE_TYPE_SLOTS && CYTHON_USE_PYTYPE_LOOKUP && PY_VERSION_HEX < 0x03070000
static CYTHON_INLINE PyObject* __Pyx_PyObject_GenericGetAttrNoDict(PyObject* obj, PyObject* attr_name);
#else
#define __Pyx_PyObject_GenericGetAttrNoDict PyObject_GenericGetAttr
#endif

/* PyObject_GenericGetAttr.proto */
#if CYTHON_USE_TYPE_SLOTS && CYTHON_USE_PYTYPE_LOOKUP && PY_VERSION_HEX < 0x03070000
static PyObject* __Pyx_PyObject_GenericGetAttr(PyObject* obj, PyObject* attr_name);
#else
#define __Pyx_PyObject_GenericGetAttr PyObject_GenericGetAttr
#endif

/* SetVTable.proto */
static int __Pyx_SetVtable(PyObject *dict, void *vtable);

/* SetupReduce.proto */
static int __Pyx_setup_reduce(PyObject* type_obj);

/* TypeImport.proto */
#ifndef __PYX_HAVE_RT_ImportType_proto
#define __PYX_HAVE_RT_ImportType_proto
enum __Pyx_ImportType_CheckSize {
   __Pyx_ImportType_CheckSize_Error = 0,
   __Pyx_ImportType_CheckSize_Warn = 1,
   __Pyx_ImportType_CheckSize_Ignore = 2
};
static PyTypeObject *__Pyx_ImportType(PyObject* module, const char *module_name, const char *class_name, size_t size, enum __Pyx_ImportType_CheckSize check_size);
#endif

/* CLineInTraceback.proto */
#ifdef CYTHON_CLINE_IN_TRACEBACK
#define __Pyx_CLineForTraceback(tstate, c_line)  (((CYTHON_CLINE_IN_TRACEBACK)) ? c_line : 0)
#else
static int __Pyx_CLineForTraceback(PyThreadState *tstate, int c_line);
#endif

/* CodeObjectCache.proto */
typedef struct {
    PyCodeObject* code_object;
    int code_line;
} __Pyx_CodeObjectCacheEntry;
struct __Pyx_CodeObjectCache {
    int count;
    int max_count;
    __Pyx_CodeObjectCacheEntry* entries;
};
static struct __Pyx_CodeObjectCache __pyx_code_cache = {0,0,NULL};
static int __pyx_bisect_code_objects(__Pyx_CodeObjectCacheEntry* entries, int count, int code_line);
static PyCodeObject *__pyx_find_code_object(int code_line);
static void __pyx_insert_code_object(int code_line, PyCodeObject* code_object);

/* AddTraceback.proto */
static void __Pyx_AddTraceback(const char *funcname, int c_line,
                               int py_line, const char *filename);

/* ArrayAPI.proto */
#ifndef _ARRAYARRAY_H
#define _ARRAYARRAY_H
typedef struct arraydescr {
    int typecode;
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#if PY_MAJOR_VERSION >= 3
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} arraydescr;
struct arrayobject {
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        PyErr_BadInternalCall();
        return NULL;
    }
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        return PyErr_NoMemory();
    }
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        return NULL;
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    return (PyObject *) op;
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PyObject* newarrayobject(PyTypeObject *type, Py_ssize_t size,
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    PyMem_Resize(items, char, (size_t)(newsize * self->ob_descr->itemsize));
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/* ToPyCTupleUtility.proto */
static PyObject* __pyx_convert__to_py___pyx_ctuple_int__and_int(__pyx_ctuple_int__and_int);

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/* CIntToPy.proto */
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/* FromPyCTupleUtility.proto */
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    #define __Pyx_SET_CREAL(z,x) ((z).real(x))
    #define __Pyx_SET_CIMAG(z,y) ((z).imag(y))
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    #define __Pyx_SET_CREAL(z,x) __Pyx_CREAL(z) = (x)
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/* Arithmetic.proto */
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    #define __Pyx_c_eq_float(a, b)   ((a)==(b))
    #define __Pyx_c_sum_float(a, b)  ((a)+(b))
    #define __Pyx_c_diff_float(a, b) ((a)-(b))
    #define __Pyx_c_prod_float(a, b) ((a)*(b))
    #define __Pyx_c_quot_float(a, b) ((a)/(b))
    #define __Pyx_c_neg_float(a)     (-(a))
  #ifdef __cplusplus
    #define __Pyx_c_is_zero_float(z) ((z)==(float)0)
    #define __Pyx_c_conj_float(z)    (::std::conj(z))
    #if 1
        #define __Pyx_c_abs_float(z)     (::std::abs(z))
        #define __Pyx_c_pow_float(a, b)  (::std::pow(a, b))
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  #else
    #define __Pyx_c_is_zero_float(z) ((z)==0)
    #define __Pyx_c_conj_float(z)    (conjf(z))
    #if 1
        #define __Pyx_c_abs_float(z)     (cabsf(z))
        #define __Pyx_c_pow_float(a, b)  (cpowf(a, b))
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    static CYTHON_INLINE int __Pyx_c_eq_float(__pyx_t_float_complex, __pyx_t_float_complex);
    static CYTHON_INLINE __pyx_t_float_complex __Pyx_c_sum_float(__pyx_t_float_complex, __pyx_t_float_complex);
    static CYTHON_INLINE __pyx_t_float_complex __Pyx_c_diff_float(__pyx_t_float_complex, __pyx_t_float_complex);
    static CYTHON_INLINE __pyx_t_float_complex __Pyx_c_prod_float(__pyx_t_float_complex, __pyx_t_float_complex);
    static CYTHON_INLINE __pyx_t_float_complex __Pyx_c_quot_float(__pyx_t_float_complex, __pyx_t_float_complex);
    static CYTHON_INLINE __pyx_t_float_complex __Pyx_c_neg_float(__pyx_t_float_complex);
    static CYTHON_INLINE int __Pyx_c_is_zero_float(__pyx_t_float_complex);
    static CYTHON_INLINE __pyx_t_float_complex __Pyx_c_conj_float(__pyx_t_float_complex);
    #if 1
        static CYTHON_INLINE float __Pyx_c_abs_float(__pyx_t_float_complex);
        static CYTHON_INLINE __pyx_t_float_complex __Pyx_c_pow_float(__pyx_t_float_complex, __pyx_t_float_complex);
    #endif
#endif

/* Arithmetic.proto */
#if CYTHON_CCOMPLEX
    #define __Pyx_c_eq_double(a, b)   ((a)==(b))
    #define __Pyx_c_sum_double(a, b)  ((a)+(b))
    #define __Pyx_c_diff_double(a, b) ((a)-(b))
    #define __Pyx_c_prod_double(a, b) ((a)*(b))
    #define __Pyx_c_quot_double(a, b) ((a)/(b))
    #define __Pyx_c_neg_double(a)     (-(a))
  #ifdef __cplusplus
    #define __Pyx_c_is_zero_double(z) ((z)==(double)0)
    #define __Pyx_c_conj_double(z)    (::std::conj(z))
    #if 1
        #define __Pyx_c_abs_double(z)     (::std::abs(z))
        #define __Pyx_c_pow_double(a, b)  (::std::pow(a, b))
    #endif
  #else
    #define __Pyx_c_is_zero_double(z) ((z)==0)
    #define __Pyx_c_conj_double(z)    (conj(z))
    #if 1
        #define __Pyx_c_abs_double(z)     (cabs(z))
        #define __Pyx_c_pow_double(a, b)  (cpow(a, b))
    #endif
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    static CYTHON_INLINE int __Pyx_c_eq_double(__pyx_t_double_complex, __pyx_t_double_complex);
    static CYTHON_INLINE __pyx_t_double_complex __Pyx_c_sum_double(__pyx_t_double_complex, __pyx_t_double_complex);
    static CYTHON_INLINE __pyx_t_double_complex __Pyx_c_diff_double(__pyx_t_double_complex, __pyx_t_double_complex);
    static CYTHON_INLINE __pyx_t_double_complex __Pyx_c_prod_double(__pyx_t_double_complex, __pyx_t_double_complex);
    static CYTHON_INLINE __pyx_t_double_complex __Pyx_c_quot_double(__pyx_t_double_complex, __pyx_t_double_complex);
    static CYTHON_INLINE __pyx_t_double_complex __Pyx_c_neg_double(__pyx_t_double_complex);
    static CYTHON_INLINE int __Pyx_c_is_zero_double(__pyx_t_double_complex);
    static CYTHON_INLINE __pyx_t_double_complex __Pyx_c_conj_double(__pyx_t_double_complex);
    #if 1
        static CYTHON_INLINE double __Pyx_c_abs_double(__pyx_t_double_complex);
        static CYTHON_INLINE __pyx_t_double_complex __Pyx_c_pow_double(__pyx_t_double_complex, __pyx_t_double_complex);
    #endif
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/* CIntToPy.proto */
static CYTHON_INLINE PyObject* __Pyx_PyInt_From_enum__NPY_TYPES(enum NPY_TYPES value);

/* CIntFromPy.proto */
static CYTHON_INLINE int __Pyx_PyInt_As_int(PyObject *);

/* MemviewSliceCopyTemplate.proto */
static __Pyx_memviewslice
__pyx_memoryview_copy_new_contig(const __Pyx_memviewslice *from_mvs,
                                 const char *mode, int ndim,
                                 size_t sizeof_dtype, int contig_flag,
                                 int dtype_is_object);

/* CIntFromPy.proto */
static CYTHON_INLINE char __Pyx_PyInt_As_char(PyObject *);

/* CIntFromPy.proto */
static CYTHON_INLINE long __Pyx_PyInt_As_long(PyObject *);

/* FetchCommonType.proto */
static PyTypeObject* __Pyx_FetchCommonType(PyTypeObject* type);

/* CoroutineBase.proto */
typedef PyObject *(*__pyx_coroutine_body_t)(PyObject *, PyThreadState *, PyObject *);
#if CYTHON_USE_EXC_INFO_STACK
#define __Pyx_ExcInfoStruct  _PyErr_StackItem
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typedef struct {
    PyObject *exc_type;
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    PyObject *exc_traceback;
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typedef struct {
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    __pyx_coroutine_body_t body;
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    __Pyx_ExcInfoStruct gi_exc_state;
    PyObject *gi_weakreflist;
    PyObject *classobj;
    PyObject *yieldfrom;
    PyObject *gi_name;
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    PyObject *gi_modulename;
    PyObject *gi_code;
    int resume_label;
    char is_running;
} __pyx_CoroutineObject;
static __pyx_CoroutineObject *__Pyx__Coroutine_New(
    PyTypeObject *type, __pyx_coroutine_body_t body, PyObject *code, PyObject *closure,
    PyObject *name, PyObject *qualname, PyObject *module_name);
static __pyx_CoroutineObject *__Pyx__Coroutine_NewInit(
            __pyx_CoroutineObject *gen, __pyx_coroutine_body_t body, PyObject *code, PyObject *closure,
            PyObject *name, PyObject *qualname, PyObject *module_name);
static CYTHON_INLINE void __Pyx_Coroutine_ExceptionClear(__Pyx_ExcInfoStruct *self);
static int __Pyx_Coroutine_clear(PyObject *self);
static PyObject *__Pyx_Coroutine_Send(PyObject *self, PyObject *value);
static PyObject *__Pyx_Coroutine_Close(PyObject *self);
static PyObject *__Pyx_Coroutine_Throw(PyObject *gen, PyObject *args);
#if CYTHON_USE_EXC_INFO_STACK
#define __Pyx_Coroutine_SwapException(self)
#define __Pyx_Coroutine_ResetAndClearException(self)  __Pyx_Coroutine_ExceptionClear(&(self)->gi_exc_state)
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#define __Pyx_Coroutine_SwapException(self) {\
    __Pyx_ExceptionSwap(&(self)->gi_exc_state.exc_type, &(self)->gi_exc_state.exc_value, &(self)->gi_exc_state.exc_traceback);\
    __Pyx_Coroutine_ResetFrameBackpointer(&(self)->gi_exc_state);\
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#define __Pyx_Coroutine_ResetAndClearException(self) {\
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#define __Pyx_PyGen_FetchStopIterationValue(pvalue)\
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static int __Pyx_PyGen__FetchStopIterationValue(PyThreadState *tstate, PyObject **pvalue);
static CYTHON_INLINE void __Pyx_Coroutine_ResetFrameBackpointer(__Pyx_ExcInfoStruct *exc_state);

/* PatchModuleWithCoroutine.proto */
static PyObject* __Pyx_Coroutine_patch_module(PyObject* module, const char* py_code);

/* PatchGeneratorABC.proto */
static int __Pyx_patch_abc(void);

/* Generator.proto */
#define __Pyx_Generator_USED
static PyTypeObject *__pyx_GeneratorType = 0;
#define __Pyx_Generator_CheckExact(obj) (Py_TYPE(obj) == __pyx_GeneratorType)
#define __Pyx_Generator_New(body, code, closure, name, qualname, module_name)\
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/* TypeInfoCompare.proto */
static int __pyx_typeinfo_cmp(__Pyx_TypeInfo *a, __Pyx_TypeInfo *b);

/* MemviewSliceValidateAndInit.proto */
static int __Pyx_ValidateAndInit_memviewslice(
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/* ObjectToMemviewSlice.proto */
static CYTHON_INLINE __Pyx_memviewslice __Pyx_PyObject_to_MemoryviewSlice_ds_nn___pyx_t_13_rnaseq_utils_float32(PyObject *, int writable_flag);

/* ObjectToMemviewSlice.proto */
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/* CheckBinaryVersion.proto */
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/* InitStrings.proto */
static int __Pyx_InitStrings(__Pyx_StringTabEntry *t);

static int __pyx_f_13_rnaseq_utils_13RNAseqMapping_left(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self, int __pyx_skip_dispatch); /* proto*/
static int __pyx_f_13_rnaseq_utils_13RNAseqMapping_right(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self, int __pyx_skip_dispatch); /* proto*/
static int __pyx_f_13_rnaseq_utils_13RNAseqMapping_get_length(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self, int __pyx_skip_dispatch); /* proto*/
static PyObject *__pyx_f_13_rnaseq_utils_13RNAseqMapping_gaps(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self, int __pyx_skip_dispatch); /* proto*/
static PyObject *__pyx_f_13_rnaseq_utils_13RNAseqMapping_junctions(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self, int __pyx_skip_dispatch); /* proto*/
static int __pyx_f_13_rnaseq_utils_13RNAseqMapping_diff(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self, PyObject *__pyx_v_other, int __pyx_skip_dispatch); /* proto*/
static int __pyx_f_13_rnaseq_utils_13RNAseqMapping_overlaps(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self, struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_other, int __pyx_skip_dispatch); /* proto*/
static __pyx_ctuple_int__and_int __pyx_f_13_rnaseq_utils_13RNAseqMapping_overlap_range(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self, struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_other, int __pyx_skip_dispatch); /* proto*/
static int __pyx_f_13_rnaseq_utils_13RNAseqMapping_ends_clash(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self, struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_other, int __pyx_skip_dispatch); /* proto*/
static int __pyx_f_13_rnaseq_utils_13RNAseqMapping_splice_match(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self, struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_other, int __pyx_skip_dispatch, struct __pyx_opt_args_13_rnaseq_utils_13RNAseqMapping_splice_match *__pyx_optional_args); /* proto*/
static int __pyx_f_13_rnaseq_utils_13RNAseqMapping_antisense_match(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self, struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_other, int __pyx_v_end_extend, int __pyx_skip_dispatch); /* proto*/
static int __pyx_f_13_rnaseq_utils_13RNAseqMapping_sense_match(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self, struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_other, int __pyx_v_end_extend, int __pyx_skip_dispatch); /* proto*/
static int __pyx_f_13_rnaseq_utils_13RNAseqMapping_is_compatible(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self, struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_other, int __pyx_skip_dispatch, struct __pyx_opt_args_13_rnaseq_utils_13RNAseqMapping_is_compatible *__pyx_optional_args); /* proto*/
static int __pyx_f_13_rnaseq_utils_13RNAseqMapping_is_identical(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self, struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_other, int __pyx_skip_dispatch); /* proto*/
static int __pyx_f_13_rnaseq_utils_13RNAseqMapping_merge(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self, struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_other, int __pyx_skip_dispatch); /* proto*/
static PyObject *__pyx_f_13_rnaseq_utils_13RNAseqMapping_write_as_elr(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self, int __pyx_skip_dispatch, struct __pyx_opt_args_13_rnaseq_utils_13RNAseqMapping_write_as_elr *__pyx_optional_args); /* proto*/
static PyObject *__pyx_f_13_rnaseq_utils_13RNAseqMapping_write_as_bed(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self, PyObject *__pyx_v_chrom_array, PyObject *__pyx_v_source_array, int __pyx_skip_dispatch, struct __pyx_opt_args_13_rnaseq_utils_13RNAseqMapping_write_as_bed *__pyx_optional_args); /* proto*/
static PyObject *__pyx_f_13_rnaseq_utils_13RNAseqDataset_add_source(struct __pyx_obj_13_rnaseq_utils_RNAseqDataset *__pyx_v_self, PyObject *__pyx_v_source_string, int __pyx_skip_dispatch); /* proto*/
static PyObject *__pyx_f_13_rnaseq_utils_13RNAseqDataset_add_chrom(struct __pyx_obj_13_rnaseq_utils_RNAseqDataset *__pyx_v_self, PyObject *__pyx_v_chrom_string, int __pyx_skip_dispatch); /* proto*/
static PyObject *__pyx_f_13_rnaseq_utils_13RNAseqDataset_add_read_from_BED(struct __pyx_obj_13_rnaseq_utils_RNAseqDataset *__pyx_v_self, PyObject *__pyx_v_bed_line, int __pyx_skip_dispatch, struct __pyx_opt_args_13_rnaseq_utils_13RNAseqDataset_add_read_from_BED *__pyx_optional_args); /* proto*/
static PyObject *__pyx_f_13_rnaseq_utils_13RNAseqDataset_add_read(struct __pyx_obj_13_rnaseq_utils_RNAseqDataset *__pyx_v_self, PyObject *__pyx_v_input_data, int __pyx_skip_dispatch); /* proto*/
static PyObject *__pyx_f_13_rnaseq_utils_13RNAseqDataset_add_read_from_ELR(struct __pyx_obj_13_rnaseq_utils_RNAseqDataset *__pyx_v_self, PyObject *__pyx_v_elr_line, int __pyx_skip_dispatch); /* proto*/
static PyObject *__pyx_f_13_rnaseq_utils_13RNAseqDataset_add_read_from_BAM(struct __pyx_obj_13_rnaseq_utils_RNAseqDataset *__pyx_v_self, PyObject *__pyx_v_bam_lines, int __pyx_skip_dispatch, struct __pyx_opt_args_13_rnaseq_utils_13RNAseqDataset_add_read_from_BAM *__pyx_optional_args); /* proto*/
static PyObject *__pyx_f_13_rnaseq_utils_13RNAseqDataset_pop_read(struct __pyx_obj_13_rnaseq_utils_RNAseqDataset *__pyx_v_self, int __pyx_skip_dispatch, struct __pyx_opt_args_13_rnaseq_utils_13RNAseqDataset_pop_read *__pyx_optional_args); /* proto*/
static PyObject *__pyx_f_13_rnaseq_utils_13RNAseqDataset_dump_header(struct __pyx_obj_13_rnaseq_utils_RNAseqDataset *__pyx_v_self, int __pyx_skip_dispatch); /* proto*/
static PyObject *__pyx_f_13_rnaseq_utils_16AnnotationObject_parse_attributes(CYTHON_UNUSED struct __pyx_obj_13_rnaseq_utils_AnnotationObject *__pyx_v_self, PyObject *__pyx_v_attr_string, PyObject *__pyx_v_attr_format, int __pyx_skip_dispatch); /* proto*/
static PyObject *__pyx_f_13_rnaseq_utils_17AnnotationDataset_import_annotation(struct __pyx_obj_13_rnaseq_utils_AnnotationDataset *__pyx_v_self, PyObject *__pyx_v_filename, PyObject *__pyx_v_name, int __pyx_skip_dispatch); /* proto*/
static PyObject *__pyx_f_13_rnaseq_utils_17AnnotationDataset_get_transcript_fasta(struct __pyx_obj_13_rnaseq_utils_AnnotationDataset *__pyx_v_self, struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_transcript, int __pyx_skip_dispatch); /* proto*/
static struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_f_13_rnaseq_utils_17AnnotationDataset_parse_bed_line(struct __pyx_obj_13_rnaseq_utils_AnnotationDataset *__pyx_v_self, PyObject *__pyx_v_line); /* proto*/
static struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_f_13_rnaseq_utils_17AnnotationDataset_parse_elr_line(CYTHON_UNUSED struct __pyx_obj_13_rnaseq_utils_AnnotationDataset *__pyx_v_self, PyObject *__pyx_v_line, PyObject *__pyx_v_name, PyObject *__pyx_v_counter); /* proto*/
static struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_f_13_rnaseq_utils_17AnnotationDataset_anno_to_mapping_object(struct __pyx_obj_13_rnaseq_utils_AnnotationDataset *__pyx_v_self, struct __pyx_obj_13_rnaseq_utils_AnnotationObject *__pyx_v_parent, PyObject *__pyx_v_children, int __pyx_v_source, int __pyx_skip_dispatch); /* proto*/
static PyObject *__pyx_f_13_rnaseq_utils_9BAMobject_generate_read(struct __pyx_obj_13_rnaseq_utils_BAMobject *__pyx_v_self, int __pyx_skip_dispatch); /* proto*/
static int __pyx_f_13_rnaseq_utils_9BAMobject_get_mapping_number(struct __pyx_obj_13_rnaseq_utils_BAMobject *__pyx_v_self); /* proto*/
static __pyx_ctuple_int__and_int __pyx_f_13_rnaseq_utils_9BAMobject_determine_strand(CYTHON_UNUSED struct __pyx_obj_13_rnaseq_utils_BAMobject *__pyx_v_self, PyObject *__pyx_v_line, int __pyx_v_stranded); /* proto*/
static int __pyx_f_13_rnaseq_utils_9BAMobject_should_skip(struct __pyx_obj_13_rnaseq_utils_BAMobject *__pyx_v_self, PyObject *__pyx_v_line); /* proto*/
static int __pyx_f_13_rnaseq_utils_9BAMobject_fails_stringent_filters(struct __pyx_obj_13_rnaseq_utils_BAMobject *__pyx_v_self, int __pyx_v_Nmap, int __pyx_v_match_length, int __pyx_v_head, int __pyx_v_tail, int __pyx_v_errors); /* proto*/
static int __pyx_f_13_rnaseq_utils_9BAMobject_get_alignment_strand(CYTHON_UNUSED struct __pyx_obj_13_rnaseq_utils_BAMobject *__pyx_v_self, PyObject *__pyx_v_line); /* proto*/
static PyObject *__pyx_f_13_rnaseq_utils_9BAMobject_get_splice_info(struct __pyx_obj_13_rnaseq_utils_BAMobject *__pyx_v_self, PyObject *__pyx_v_ranges, PyObject *__pyx_v_introns, PyObject *__pyx_v_chrom, int __pyx_v_alignment_strand); /* proto*/
static __pyx_ctuple_int__and_int__and_int __pyx_f_13_rnaseq_utils_9BAMobject_filter_labels_by_softclip_length(CYTHON_UNUSED struct __pyx_obj_13_rnaseq_utils_BAMobject *__pyx_v_self, int __pyx_v_s_tag, int __pyx_v_e_tag, int __pyx_v_capped, int __pyx_v_fiveprime, int __pyx_v_threeprime, int __pyx_v_strand, int __pyx_v_head, int __pyx_v_tail); /* proto*/
static int __pyx_f_13_rnaseq_utils_9BAMobject_untemplated_upstream_g(struct __pyx_obj_13_rnaseq_utils_BAMobject *__pyx_v_self, int __pyx_v_strand, int __pyx_v_head, int __pyx_v_tail, PyObject *__pyx_v_seq, PyObject *__pyx_v_chrom, PyObject *__pyx_v_ranges); /* proto*/
static void __pyx_f_13_rnaseq_utils_9BAMobject_restore_terminal_mismatches(CYTHON_UNUSED struct __pyx_obj_13_rnaseq_utils_BAMobject *__pyx_v_self, int __pyx_v_strand, int __pyx_v_head, int __pyx_v_tail, PyObject *__pyx_v_ranges); /* proto*/
static int __pyx_f_13_rnaseq_utils_9BAMobject_matches_masking_sequence(struct __pyx_obj_13_rnaseq_utils_BAMobject *__pyx_v_self, PyObject *__pyx_v_chrom, int __pyx_v_position, int __pyx_v_strand, PyObject *__pyx_v_readtype, int __pyx_v_length); /* proto*/
static PyObject *__pyx_f_13_rnaseq_utils_16BranchpointArray_bp_from_counter(struct __pyx_obj_13_rnaseq_utils_BranchpointArray *__pyx_v_self, PyObject *__pyx_v_counter, PyObject *__pyx_v_branchtype, char __pyx_v_strand, int __pyx_skip_dispatch); /* proto*/
static int __pyx_f_13_rnaseq_utils_16BranchpointArray_distance_from_edge(struct __pyx_obj_13_rnaseq_utils_BranchpointArray *__pyx_v_self, int __pyx_v_pos, char __pyx_v_strand, PyObject *__pyx_v_branchtype, int __pyx_skip_dispatch); /* proto*/
static void __pyx_f_13_rnaseq_utils_16BranchpointArray_add_endpoint(struct __pyx_obj_13_rnaseq_utils_BranchpointArray *__pyx_v_self, struct __pyx_obj_13_rnaseq_utils_BranchPoint *__pyx_v_BP, int __pyx_skip_dispatch, struct __pyx_opt_args_13_rnaseq_utils_16BranchpointArray_add_endpoint *__pyx_optional_args); /* proto*/
static PyObject *__pyx_f_13_rnaseq_utils_16BranchpointArray_infer_unknown_branchpoints(struct __pyx_obj_13_rnaseq_utils_BranchpointArray *__pyx_v_self, PyObject *__pyx_v_branchpoints, int __pyx_skip_dispatch); /* proto*/
static void __pyx_f_13_rnaseq_utils_16BranchpointArray_remove_branchpoint(struct __pyx_obj_13_rnaseq_utils_BranchpointArray *__pyx_v_self, PyObject *__pyx_v_strand, int __pyx_v_index, int __pyx_skip_dispatch); /* proto*/
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static PyObject *__pyx_f_13_rnaseq_utils_overlap_type(PyObject *, PyObject *, int __pyx_skip_dispatch); /*proto*/
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static const char __pyx_k_D[] = "D";
static const char __pyx_k_E[] = "E";
static const char __pyx_k_G[] = "G";
static const char __pyx_k_N[] = "N";
static const char __pyx_k_O[] = "O";
static const char __pyx_k_S[] = "S";
static const char __pyx_k_T[] = "T";
static const char __pyx_k_U[] = "U";
static const char __pyx_k_X[] = "X";
static const char __pyx_k_c[] = "c";
static const char __pyx_k_e[] = "e";
static const char __pyx_k_i[] = "i";
static const char __pyx_k_l[] = "l";
static const char __pyx_k_r[] = "r";
static const char __pyx_k_s[] = "s";
static const char __pyx_k_AD[] = "AD";
static const char __pyx_k_BP[] = "BP";
static const char __pyx_k_DA[] = "DA";
static const char __pyx_k_ES[] = "ES";
static const char __pyx_k_HI[] = "HI";
static const char __pyx_k_ID[] = "ID";
static const char __pyx_k_MD[] = "MD";
static const char __pyx_k_NH[] = "NH";
static const char __pyx_k_NM[] = "NM";
static const char __pyx_k_OA[] = "OA({})";
static const char __pyx_k_SE[] = "SE";
static const char __pyx_k_XS[] = "XS";
static const char __pyx_k__2[] = "<";
static const char __pyx_k__3[] = "|";
static const char __pyx_k__4[] = "^";
static const char __pyx_k__5[] = "_";
static const char __pyx_k__6[] = "{}-{}";
static const char __pyx_k__7[] = "";
static const char __pyx_k__8[] = ".";
static const char __pyx_k__9[] = "..";
static const char __pyx_k_fu[] = "fu";
static const char __pyx_k_id[] = "id";
static const char __pyx_k_np[] = "np";
static const char __pyx_k_rc[] = "rc";
static const char __pyx_k_ts[] = "ts";
static const char __pyx_k_BED[] = "BED";
static const char __pyx_k_COV[] = "COV";
static const char __pyx_k_C_2[] = "#C {} {}";
static const char __pyx_k_C_3[] = "#C";
static const char __pyx_k_ELR[] = "ELR";
static const char __pyx_k_GFF[] = "GFF";
static const char __pyx_k_GTF[] = "GTF";
static const char __pyx_k_S_2[] = "#S {} {}";
static const char __pyx_k_S_3[] = "#S";
static const char __pyx_k_TAG[] = "_TAG=";
static const char __pyx_k_TPM[] = "TPM";
static const char __pyx_k__10[] = "+";
static const char __pyx_k__11[] = "-";
static const char __pyx_k__12[] = "\t";
static const char __pyx_k__13[] = ",";
static const char __pyx_k__14[] = "{}\t{}\t{}\t{}\t{}\t{}\t{}\t{}\t{}\n";
static const char __pyx_k__18[] = " ";
static const char __pyx_k__19[] = "{} \"{}\";";
static const char __pyx_k__20[] = "{}={};";
static const char __pyx_k__21[] = "\\\n        };";
static const char __pyx_k__23[] = "#";
static const char __pyx_k__25[] = "; ";
static const char __pyx_k__26[] = "\";";
static const char __pyx_k__27[] = " \"";
static const char __pyx_k__28[] = ";";
static const char __pyx_k__29[] = "=";
static const char __pyx_k__37[] = "/";
static const char __pyx_k__39[] = "{}.{}";
static const char __pyx_k__49[] = "{}{}{} ({})";
static const char __pyx_k__50[] = "{}\t{}\t{}\t{}\t{}\t{}";
static const char __pyx_k__78[] = "*";
static const char __pyx_k_add[] = "add";
static const char __pyx_k_all[] = "all";
static const char __pyx_k_arr[] = "arr";
static const char __pyx_k_ast[] = "ast";
static const char __pyx_k_bam[] = "bam";
static const char __pyx_k_bed[] = "bed";
static const char __pyx_k_cov[] = "cov";
static const char __pyx_k_elr[] = "elr";
static const char __pyx_k_gap[] = "gap";
static const char __pyx_k_get[] = "get";
static const char __pyx_k_gff[] = "gff";
static const char __pyx_k_gtf[] = "gtf";
static const char __pyx_k_key[] = "key";
static const char __pyx_k_max[] = "max";
static const char __pyx_k_new[] = "__new__";
static const char __pyx_k_obj[] = "obj";
static const char __pyx_k_pop[] = "pop";
static const char __pyx_k_pos[] = "pos";
static const char __pyx_k_sam[] = "sam";
static const char __pyx_k_sum[] = "sum";
static const char __pyx_k_zip[] = "zip";
static const char __pyx_k_ATAC[] = "ATAC";
static const char __pyx_k_CCAC[] = "CCAC";
static const char __pyx_k_CTAC[] = "CTAC";
static const char __pyx_k_CTGC[] = "CTGC";
static const char __pyx_k_GCAG[] = "GCAG";
static const char __pyx_k_GFF3[] = "GFF3";
static const char __pyx_k_GTAG[] = "GTAG";
static const char __pyx_k_GTAT[] = "GTAT";
static const char __pyx_k_GTGG[] = "GTGG";
static const char __pyx_k_args[] = "args";
static const char __pyx_k_base[] = "base";
static const char __pyx_k_bool[] = "bool";
static const char __pyx_k_copy[] = "copy";
static const char __pyx_k_dict[] = "__dict__";
static const char __pyx_k_diff[] = "diff";
static const char __pyx_k_exon[] = "exon";
static const char __pyx_k_full[] = "full";
static const char __pyx_k_gaps[] = "gaps";
static const char __pyx_k_gff3[] = ".gff3";
static const char __pyx_k_init[] = "__init__";
static const char __pyx_k_item[] = "item";
static const char __pyx_k_json[] = "json";
static const char __pyx_k_keys[] = "keys";
static const char __pyx_k_left[] = "left";
static const char __pyx_k_line[] = "line";
static const char __pyx_k_mRNA[] = "mRNA";
static const char __pyx_k_main[] = "__main__";
static const char __pyx_k_mode[] = "mode";
static const char __pyx_k_name[] = "name";
static const char __pyx_k_ndim[] = "ndim";
static const char __pyx_k_open[] = "open";
static const char __pyx_k_pack[] = "pack";
static const char __pyx_k_rRNA[] = "rRNA";
static const char __pyx_k_read[] = "read";
static const char __pyx_k_send[] = "send";
static const char __pyx_k_size[] = "size";
static const char __pyx_k_sort[] = "sort";
static const char __pyx_k_span[] = "span";
static const char __pyx_k_step[] = "step";
static const char __pyx_k_stop[] = "stop";
static const char __pyx_k_tRNA[] = "tRNA";
static const char __pyx_k_test[] = "__test__";
static const char __pyx_k_ACGGG[] = "ACGGG";
static const char __pyx_k_ASCII[] = "ASCII";
static const char __pyx_k_C_ppm[] = "C.ppm";
static const char __pyx_k_E_ppm[] = "E.ppm";
static const char __pyx_k_S_ppm[] = "S.ppm";
static const char __pyx_k_array[] = "array";
static const char __pyx_k_chrom[] = "chrom";
static const char __pyx_k_class[] = "__class__";
static const char __pyx_k_close[] = "close";
static const char __pyx_k_dtype[] = "dtype";
static const char __pyx_k_dumps[] = "dumps";
static const char __pyx_k_e_tag[] = "e_tag";
static const char __pyx_k_error[] = "error";
static const char __pyx_k_flags[] = "flags";
static const char __pyx_k_force[] = "force";
static const char __pyx_k_gff_2[] = ".gff";
static const char __pyx_k_gtf_2[] = ".gtf";
static const char __pyx_k_index[] = "index";
static const char __pyx_k_items[] = "items";
static const char __pyx_k_lower[] = "lower";
static const char __pyx_k_merge[] = "merge";
static const char __pyx_k_miRNA[] = "miRNA";
static const char __pyx_k_ncRNA[] = "ncRNA";
static const char __pyx_k_numpy[] = "numpy";
static const char __pyx_k_other[] = "other";
static const char __pyx_k_print[] = "print";
static const char __pyx_k_probe[] = "probe";
static const char __pyx_k_range[] = "range";
static const char __pyx_k_reads[] = "reads";
static const char __pyx_k_right[] = "right";
static const char __pyx_k_round[] = "round";
static const char __pyx_k_s_tag[] = "s_tag";
static const char __pyx_k_shape[] = "shape";
static const char __pyx_k_snRNA[] = "snRNA";
static const char __pyx_k_split[] = "split";
static const char __pyx_k_start[] = "start";
static const char __pyx_k_throw[] = "throw";
static const char __pyx_k_upper[] = "upper";
static const char __pyx_k_where[] = "where";
static const char __pyx_k_zeros[] = "zeros";
static const char __pyx_k_ELdata[] = "ELdata";
static const char __pyx_k_Parent[] = "Parent";
static const char __pyx_k_append[] = "append";
static const char __pyx_k_capped[] = "capped";
static const char __pyx_k_config[] = "config";
static const char __pyx_k_delete[] = "delete";
static const char __pyx_k_encode[] = "encode";
static const char __pyx_k_extend[] = "extend";
static const char __pyx_k_format[] = "format";
static const char __pyx_k_genome[] = "genome";
static const char __pyx_k_header[] = "header";
static const char __pyx_k_import[] = "__import__";
static const char __pyx_k_init_2[] = "init";
static const char __pyx_k_is_gap[] = "is_gap";
static const char __pyx_k_maxgap[] = "maxgap";
static const char __pyx_k_name_2[] = "__name__";
static const char __pyx_k_offset[] = "offset";
static const char __pyx_k_parent[] = "parent";
static const char __pyx_k_pickle[] = "pickle";
static const char __pyx_k_ranges[] = "ranges";
static const char __pyx_k_reduce[] = "__reduce__";
static const char __pyx_k_rstrip[] = "rstrip";
static const char __pyx_k_snoRNA[] = "snoRNA";
static const char __pyx_k_sorted[] = "sorted";
static const char __pyx_k_source[] = "source";
static const char __pyx_k_span_2[] = " \\\n        \"span\": ";
static const char __pyx_k_splice[] = "splice";
static const char __pyx_k_strand[] = "strand";
static const char __pyx_k_struct[] = "struct";
static const char __pyx_k_unpack[] = "unpack";
static const char __pyx_k_update[] = "update";
static const char __pyx_k_values[] = "values";
static const char __pyx_k_weight[] = "weight";
static const char __pyx_k_Counter[] = "Counter";
static const char __pyx_k_E_reads[] = "E.reads";
static const char __pyx_k_RAN_OUT[] = "# RAN OUT";
static const char __pyx_k_S_reads[] = "S.reads";
static const char __pyx_k_chrom_2[] = "{ \\\n        \"chrom\": ";
static const char __pyx_k_counter[] = "counter";
static const char __pyx_k_current[] = "current";
static const char __pyx_k_dataset[] = "dataset";
static const char __pyx_k_e_tag_2[] = "\\\n        \"e_tag\": ";
static const char __pyx_k_end_seq[] = "end_seq";
static const char __pyx_k_float32[] = "float32";
static const char __pyx_k_fortran[] = "fortran";
static const char __pyx_k_gene_id[] = "gene_id";
static const char __pyx_k_get_tag[] = "get_tag";
static const char __pyx_k_isdigit[] = "isdigit";
static const char __pyx_k_lnc_RNA[] = "lnc_RNA";
static const char __pyx_k_max_cov[] = "max_cov";
static const char __pyx_k_max_gap[] = "max_gap";
static const char __pyx_k_memview[] = "memview";
static const char __pyx_k_range_a[] = "range_a";
static const char __pyx_k_range_b[] = "range_b";
static const char __pyx_k_replace[] = "_replace";
static const char __pyx_k_reverse[] = "reverse";
static const char __pyx_k_s_tag_2[] = "\\\n        \"s_tag\": ";
static const char __pyx_k_verbose[] = "verbose";
static const char __pyx_k_was_gap[] = "was_gap";
static const char __pyx_k_Ellipsis[] = "Ellipsis";
static const char __pyx_k_EndPoint[] = "EndPoint";
static const char __pyx_k_IUPACham[] = "IUPACham";
static const char __pyx_k_KeyError[] = "KeyError";
static const char __pyx_k_S_capped[] = "S.capped";
static const char __pyx_k_add_read[] = "add_read";
static const char __pyx_k_bed_line[] = "bed_line";
static const char __pyx_k_capped_2[] = "\\\n        \"capped\": ";
static const char __pyx_k_children[] = "children";
static const char __pyx_k_coverage[] = "coverage";
static const char __pyx_k_deepcopy[] = "deepcopy";
static const char __pyx_k_fileconn[] = "fileconn";
static const char __pyx_k_filename[] = "filename";
static const char __pyx_k_getstate[] = "__getstate__";
static const char __pyx_k_is_digit[] = "is_digit";
static const char __pyx_k_is_read1[] = "is_read1";
static const char __pyx_k_itemsize[] = "itemsize";
static const char __pyx_k_leftmost[] = "leftmost";
static const char __pyx_k_mdstring[] = "mdstring";
static const char __pyx_k_min_reps[] = "min_reps";
static const char __pyx_k_overlaps[] = "overlaps";
static const char __pyx_k_pop_read[] = "pop_read";
static const char __pyx_k_position[] = "position";
static const char __pyx_k_pyx_type[] = "__pyx_type";
static const char __pyx_k_ranges_2[] = "\\\n        \"ranges\": ";
static const char __pyx_k_setstate[] = "__setstate__";
static const char __pyx_k_source_2[] = "\\\n        \"source\": ";
static const char __pyx_k_splice_2[] = "\\\n        \"splice\": ";
static const char __pyx_k_strand_2[] = ", \\\n        \"strand\": ";
static const char __pyx_k_stranded[] = "stranded";
static const char __pyx_k_weight_2[] = "\\\n        \"weight\": ";
static const char __pyx_k_0_212_145[] = "0,212,145";
static const char __pyx_k_190_30_45[] = "190,30,45";
static const char __pyx_k_BAMobject[] = "BAMobject";
static const char __pyx_k_Importing[] = "Importing {}...";
static const char __pyx_k_TypeError[] = "TypeError";
static const char __pyx_k_add_chrom[] = "add_chrom";
static const char __pyx_k_as_string[] = "as_string";
static const char __pyx_k_bam_lines[] = "bam_lines";
static const char __pyx_k_block_end[] = "block_end";
static const char __pyx_k_enumerate[] = "enumerate";
static const char __pyx_k_file_type[] = "file_type";
static const char __pyx_k_is_paired[] = "is_paired";
static const char __pyx_k_junctions[] = "junctions";
static const char __pyx_k_label_len[] = "label_len";
static const char __pyx_k_last_read[] = "last_read";
static const char __pyx_k_name_attr[] = "name_attr";
static const char __pyx_k_pyx_state[] = "__pyx_state";
static const char __pyx_k_reduce_ex[] = "__reduce_ex__";
static const char __pyx_k_reference[] = "reference";
static const char __pyx_k_replace_2[] = "replace";
static const char __pyx_k_rightmost[] = "rightmost";
static const char __pyx_k_secondary[] = "secondary";
static const char __pyx_k_start_seq[] = "start_seq";
static const char __pyx_k_threshold[] = "threshold";
static const char __pyx_k_was_digit[] = "was_digit";
static const char __pyx_k_109_74_116[] = "109,74,116";
static const char __pyx_k_28_117_188[] = "28,117,188";
static const char __pyx_k_DonorPoint[] = "DonorPoint";
static const char __pyx_k_IndexError[] = "IndexError";
static const char __pyx_k_StartPoint[] = "StartPoint";
static const char __pyx_k_ValueError[] = "ValueError";
static const char __pyx_k_add_source[] = "add_source";
static const char __pyx_k_attributes[] = "attributes";
static const char __pyx_k_bed_colors[] = "bed_colors";
static const char __pyx_k_branchtype[] = "branchtype";
static const char __pyx_k_comparator[] = "comparator";
static const char __pyx_k_confidence[] = "confidence";
static const char __pyx_k_end_extend[] = "end_extend";
static const char __pyx_k_ends_clash[] = "ends_clash";
static const char __pyx_k_error_rate[] = "error_rate";
static const char __pyx_k_get_length[] = "get_length";
static const char __pyx_k_gff_config[] = "gff_config";
static const char __pyx_k_gtf_config[] = "gtf_config";
static const char __pyx_k_infer_ends[] = "infer_ends";
static const char __pyx_k_input_data[] = "input_data";
static const char __pyx_k_is_reverse[] = "is_reverse";
static const char __pyx_k_label_type[] = "label_type";
static const char __pyx_k_last_chrom[] = "last_chrom";
static const char __pyx_k_last_index[] = "last_index";
static const char __pyx_k_namedtuple[] = "namedtuple";
static const char __pyx_k_nuc_to_int[] = "nuc_to_int";
static const char __pyx_k_pyx_result[] = "__pyx_result";
static const char __pyx_k_pyx_vtable[] = "__pyx_vtable__";
static const char __pyx_k_query_name[] = "query_name";
static const char __pyx_k_transcript[] = "transcript";
static const char __pyx_k_128_130_133[] = "128,130,133";
static const char __pyx_k_BranchPoint[] = "BranchPoint";
static const char __pyx_k_ImportError[] = "ImportError";
static const char __pyx_k_MemoryError[] = "MemoryError";
static const char __pyx_k_PickleError[] = "PickleError";
static const char __pyx_k_anno_string[] = "anno_string";
static const char __pyx_k_attr_format[] = "attr_format";
static const char __pyx_k_attr_string[] = "attr_string";
static const char __pyx_k_block_start[] = "block_start";
static const char __pyx_k_cap_percent[] = "cap_percent";
static const char __pyx_k_child_types[] = "child_types";
static const char __pyx_k_chrom_array[] = "chrom_array";
static const char __pyx_k_cigartuples[] = "cigartuples";
static const char __pyx_k_clean_array[] = "clean_array";
static const char __pyx_k_collections[] = "collections";
static const char __pyx_k_config_dict[] = "config_dict";
static const char __pyx_k_dump_header[] = "dump_header";
static const char __pyx_k_header_line[] = "header_line";
static const char __pyx_k_ignore_ends[] = "ignore_ends";
static const char __pyx_k_input_lines[] = "input_lines";
static const char __pyx_k_is_unmapped[] = "is_unmapped";
static const char __pyx_k_read_format[] = "read_format";
static const char __pyx_k_sense_match[] = "sense_match";
static const char __pyx_k_split_chunk[] = "split_chunk";
static const char __pyx_k_OrderedArray[] = "OrderedArray";
static const char __pyx_k_RuntimeError[] = "RuntimeError";
static const char __pyx_k_add_endpoint[] = "add_endpoint";
static const char __pyx_k_array_length[] = "array_length";
static const char __pyx_k_bp_typeorder[] = "bp_typeorder";
static const char __pyx_k_genome_fasta[] = "genome_fasta";
static const char __pyx_k_gff_defaults[] = "gff_defaults";
static const char __pyx_k_gtf_defaults[] = "gtf_defaults";
static const char __pyx_k_infer_starts[] = "infer_starts";
static const char __pyx_k_is_identical[] = "is_identical";
static const char __pyx_k_is_secondary[] = "is_secondary";
static const char __pyx_k_leading_edge[] = "leading_edge";
static const char __pyx_k_literal_eval[] = "literal_eval";
static const char __pyx_k_mRNA_TE_gene[] = "mRNA_TE_gene";
static const char __pyx_k_min_overhang[] = "min_overhang";
static const char __pyx_k_minlen_loose[] = "minlen_loose";
static const char __pyx_k_parent_types[] = "parent_types";
static const char __pyx_k_pyx_checksum[] = "__pyx_checksum";
static const char __pyx_k_reference_id[] = "reference_id";
static const char __pyx_k_rnaseq_utils[] = "_rnaseq_utils";
static const char __pyx_k_score_column[] = "score_column";
static const char __pyx_k_source_array[] = "source_array";
static const char __pyx_k_splice_match[] = "splice_match";
static const char __pyx_k_stringsource[] = "stringsource";
static const char __pyx_k_write_as_bed[] = "write_as_bed";
static const char __pyx_k_write_as_elr[] = "write_as_elr";
static const char __pyx_k_write_as_gtf[] = "write_as_gtf";
static const char __pyx_k_AcceptorPoint[] = "AcceptorPoint";
static const char __pyx_k_RNAseqDataset[] = "RNAseqDataset";
static const char __pyx_k_RNAseqMapping[] = "RNAseqMapping";
static const char __pyx_k_StopIteration[] = "StopIteration";
static const char __pyx_k_antisense_RNA[] = "antisense_RNA";
static const char __pyx_k_capped_weight[] = "capped_weight";
static const char __pyx_k_chrom_lengths[] = "chrom_lengths";
static const char __pyx_k_generate_loci[] = "generate_loci";
static const char __pyx_k_generate_read[] = "generate_read";
static const char __pyx_k_ignore_source[] = "ignore_source";
static const char __pyx_k_import_genome[] = "import_genome";
static const char __pyx_k_is_compatible[] = "is_compatible";
static const char __pyx_k_minlen_strict[] = "minlen_strict";
static const char __pyx_k_mismatch_rate[] = "mismatch_rate";
static const char __pyx_k_overlap_range[] = "overlap_range";
static const char __pyx_k_pyx_getbuffer[] = "__pyx_getbuffer";
static const char __pyx_k_reduce_cython[] = "__reduce_cython__";
static const char __pyx_k_source_string[] = "source_string";
static const char __pyx_k_transcript_id[] = "transcript_id";
static const char __pyx_k_child_key_gene[] = "child_key_gene";
static const char __pyx_k_is_proper_pair[] = "is_proper_pair";
static const char __pyx_k_ordered_values[] = "ordered_values";
static const char __pyx_k_percent_capped[] = "percent_capped";
static const char __pyx_k_query_sequence[] = "query_sequence";
static const char __pyx_k_read_generator[] = "read_generator";
static const char __pyx_k_reference_name[] = "reference_name";
static const char __pyx_k_use_attributes[] = "use_attributes";
static const char __pyx_k_RRRRRRRRRRRRRRR[] = "RRRRRRRRRRRRRRR";
static const char __pyx_k_View_MemoryView[] = "View.MemoryView";
static const char __pyx_k_allocate_buffer[] = "allocate_buffer";
static const char __pyx_k_antisense_match[] = "antisense_match";
static const char __pyx_k_array_to_blocks[] = "array_to_blocks";
static const char __pyx_k_bp_from_counter[] = "bp_from_counter";
static const char __pyx_k_config_defaults[] = "config_defaults";
static const char __pyx_k_dtype_is_object[] = "dtype_is_object";
static const char __pyx_k_get_node_labels[] = "get_node_labels";
static const char __pyx_k_number_of_reads[] = "number_of_reads";
static const char __pyx_k_parent_key_gene[] = "parent_key_gene";
static const char __pyx_k_parse_MD_string[] = "parse_MD_string";
static const char __pyx_k_pyx_PickleError[] = "__pyx_PickleError";
static const char __pyx_k_reference_start[] = "reference_start";
static const char __pyx_k_setstate_cython[] = "__setstate_cython__";
static const char __pyx_k_AnnotationObject[] = "AnnotationObject";
static const char __pyx_k_BranchpointArray[] = "BranchpointArray";
static const char __pyx_k_annotation_files[] = "annotation_files";
static const char __pyx_k_antisense_lncRNA[] = "antisense_lncRNA";
static const char __pyx_k_is_supplementary[] = "is_supplementary";
static const char __pyx_k_parse_attributes[] = "parse_attributes";
static const char __pyx_k_print_attributes[] = "print_attributes";
static const char __pyx_k_pseudogenic_exon[] = "pseudogenic_exon";
static const char __pyx_k_record_artifacts[] = "record_artifacts";
static const char __pyx_k_rnaseq_utils_pyx[] = "_rnaseq_utils.pyx";
static const char __pyx_k_AnnotationDataset[] = "AnnotationDataset";
static const char __pyx_k_add_read_from_BAM[] = "add_read_from_BAM";
static const char __pyx_k_add_read_from_BED[] = "add_read_from_BED";
static const char __pyx_k_add_read_from_ELR[] = "add_read_from_ELR";
static const char __pyx_k_import_annotation[] = "import_annotation";
static const char __pyx_k_pyx_unpickle_Enum[] = "__pyx_unpickle_Enum";
static const char __pyx_k_cline_in_traceback[] = "cline_in_traceback";
static const char __pyx_k_distance_from_edge[] = "distance_from_edge";
static const char __pyx_k_gaps_are_junctions[] = "gaps_are_junctions";
static const char __pyx_k_get_reference_name[] = "get_reference_name";
static const char __pyx_k_minimum_proportion[] = "minimum_proportion";
static const char __pyx_k_remove_branchpoint[] = "remove_branchpoint";
static const char __pyx_k_strided_and_direct[] = "<strided and direct>";
static const char __pyx_k_child_key_transcript[] = "child_key_transcript";
static const char __pyx_k_confidence_threshold[] = "confidence_threshold";
static const char __pyx_k_get_transcript_fasta[] = "get_transcript_fasta";
static const char __pyx_k_strided_and_indirect[] = "<strided and indirect>";
static const char __pyx_k_contiguous_and_direct[] = "<contiguous and direct>";
static const char __pyx_k_parent_key_transcript[] = "parent_key_transcript";
static const char __pyx_k_pyx_unpickle_EndPoint[] = "__pyx_unpickle_EndPoint";
static const char __pyx_k_MemoryView_of_r_object[] = "<MemoryView of %r object>";
static const char __pyx_k_anno_to_mapping_object[] = "anno_to_mapping_object";
static const char __pyx_k_pseudogenic_transcript[] = "pseudogenic_transcript";
static const char __pyx_k_pyx_unpickle_BAMobject[] = "__pyx_unpickle_BAMobject";
static const char __pyx_k_MemoryView_of_r_at_0x_x[] = "<MemoryView of %r at 0x%x>";
static const char __pyx_k_contiguous_and_indirect[] = "<contiguous and indirect>";
static const char __pyx_k_pyx_unpickle_DonorPoint[] = "__pyx_unpickle_DonorPoint";
static const char __pyx_k_pyx_unpickle_StartPoint[] = "__pyx_unpickle_StartPoint";
static const char __pyx_k_Cannot_index_with_type_s[] = "Cannot index with type '%s'";
static const char __pyx_k_pyx_unpickle_BranchPoint[] = "__pyx_unpickle_BranchPoint";
static const char __pyx_k_Invalid_shape_in_axis_d_d[] = "Invalid shape in axis %d: %d.";
static const char __pyx_k_pyx_unpickle_OrderedArray[] = "__pyx_unpickle_OrderedArray";
static const char __pyx_k_infer_unknown_branchpoints[] = "infer_unknown_branchpoints";
static const char __pyx_k_pyx_unpickle_AcceptorPoint[] = "__pyx_unpickle_AcceptorPoint";
static const char __pyx_k_pyx_unpickle_RNAseqDataset[] = "__pyx_unpickle_RNAseqDataset";
static const char __pyx_k_pyx_unpickle_RNAseqMapping[] = "__pyx_unpickle_RNAseqMapping";
static const char __pyx_k_itemsize_0_for_cython_array[] = "itemsize <= 0 for cython.array";
static const char __pyx_k_ndarray_is_not_C_contiguous[] = "ndarray is not C contiguous";
static const char __pyx_k_pyx_unpickle_AnnotationObject[] = "__pyx_unpickle_AnnotationObject";
static const char __pyx_k_pyx_unpickle_BranchpointArray[] = "__pyx_unpickle_BranchpointArray";
static const char __pyx_k_unable_to_allocate_array_data[] = "unable to allocate array data.";
static const char __pyx_k_pyx_unpickle_AnnotationDataset[] = "__pyx_unpickle_AnnotationDataset";
static const char __pyx_k_strided_and_direct_or_indirect[] = "<strided and direct or indirect>";
static const char __pyx_k_AnnotationDataset_generate_loci[] = "AnnotationDataset.generate_loci";
static const char __pyx_k_numpy_core_multiarray_failed_to[] = "numpy.core.multiarray failed to import";
static const char __pyx_k_unknown_dtype_code_in_numpy_pxd[] = "unknown dtype code in numpy.pxd (%d)";
static const char __pyx_k_Buffer_view_does_not_expose_stri[] = "Buffer view does not expose strides";
static const char __pyx_k_Can_only_create_a_buffer_that_is[] = "Can only create a buffer that is contiguous in memory.";
static const char __pyx_k_Cannot_assign_to_read_only_memor[] = "Cannot assign to read-only memoryview";
static const char __pyx_k_Cannot_create_writable_memory_vi[] = "Cannot create writable memory view from read-only memoryview";
static const char __pyx_k_Empty_shape_tuple_for_cython_arr[] = "Empty shape tuple for cython.array";
static const char __pyx_k_Format_string_allocated_too_shor[] = "Format string allocated too short, see comment in numpy.pxd";
static const char __pyx_k_Incompatible_checksums_s_vs_0x10[] = "Incompatible checksums (%s vs 0x10ef510 = (branchtype, comparator, index, left, pos, right, strand, weight))";
static const char __pyx_k_Incompatible_checksums_s_vs_0x20[] = "Incompatible checksums (%s vs 0x20713a3 = (dataset, ignore_ends, input_lines, secondary))";
static const char __pyx_k_Incompatible_checksums_s_vs_0x23[] = "Incompatible checksums (%s vs 0x23392f6 = (branchtype, comparator, extend, index, left, pos, right, span, strand, weight))";
static const char __pyx_k_Incompatible_checksums_s_vs_0x28[] = "Incompatible checksums (%s vs 0x281c8b4 = (attributes, capped, chrom, complete, coverage, e_len, e_tag, is_reference, ranges, s_len, s_tag, source, span, splice, strand, weight))";
static const char __pyx_k_Incompatible_checksums_s_vs_0x78[] = "Incompatible checksums (%s vs 0x78d6b95 = (E_minus, E_plus, J_minus, J_plus, S_minus, S_plus, bp_minus, bp_plus, branchpoints, cap_percent, depth, end_extend, extend, infer_ends, infer_starts, leftmost, length, min_overhang, minimum_proportion, rightmost, threshold, use_attributes, weight))";
static const char __pyx_k_Incompatible_checksums_s_vs_0x85[] = "Incompatible checksums (%s vs 0x854e66c = (n, ordered_array))";
static const char __pyx_k_Incompatible_checksums_s_vs_0xb0[] = "Incompatible checksums (%s vs 0xb068931 = (name))";
static const char __pyx_k_Incompatible_checksums_s_vs_0xc8[] = "Incompatible checksums (%s vs 0xc8c7f26 = (anno_type, attributes, chrom, fields, format, gene_id, keep, parent, source, span, strand, transcript_id))";
static const char __pyx_k_Incompatible_checksums_s_vs_0xd4[] = "Incompatible checksums (%s vs 0xd40dfa4 = (annotations, cap_percent, capped, chrom_array, chrom_dict, chrom_index, chrom_lengths, confidence, config, counter, e_tag, end_array, end_seq, generator, genome, gff_config, gtf_config, ignore_ends, label_tally, min_reps, minlen, minlen_loose, minlen_strict, mismatch_rate, number_of_assemblies, read_list, s_tag, source_array, source_dict, source_index, start_array, start_seq, stranded, verbose))";
static const char __pyx_k_Incompatible_checksums_s_vs_0xdc[] = "Incompatible checksums (%s vs 0xdc9f8eb = (capped, chrom_array, chrom_dict, chrom_index, chrom_lengths, config, e_tag, end_array, end_seq, genome, ignore_ends, label_tally, minlen, minlen_loose, minlen_strict, mismatch_rate, read_list, s_tag, source_array, source_dict, source_index, start_array, start_seq, stranded))";
static const char __pyx_k_Indirect_dimensions_not_supporte[] = "Indirect dimensions not supported";
static const char __pyx_k_Invalid_mode_expected_c_or_fortr[] = "Invalid mode, expected 'c' or 'fortran', got %s";
static const char __pyx_k_Non_native_byte_order_not_suppor[] = "Non-native byte order not supported";
static const char __pyx_k_Out_of_bounds_on_buffer_access_a[] = "Out of bounds on buffer access (axis %d)";
static const char __pyx_k_Unable_to_convert_item_to_object[] = "Unable to convert item to object";
static const char __pyx_k_bookend_core_cython_utils__fasta[] = "bookend.core.cython_utils._fasta_utils";
static const char __pyx_k_chrom_source_strand_ranges_splic[] = "chrom source strand ranges splice s_tag e_tag capped weight";
static const char __pyx_k_got_differing_extents_in_dimensi[] = "got differing extents in dimension %d (got %d and %d)";
static const char __pyx_k_ndarray_is_not_Fortran_contiguou[] = "ndarray is not Fortran contiguous";
static const char __pyx_k_no_default___reduce___due_to_non[] = "no default __reduce__ due to non-trivial __cinit__";
static const char __pyx_k_numpy_core_umath_failed_to_impor[] = "numpy.core.umath failed to import";
static const char __pyx_k_unable_to_allocate_shape_and_str[] = "unable to allocate shape and strides.";
static const char __pyx_k_Format_string_allocated_too_shor_2[] = "Format string allocated too short.";
static const char __pyx_k_Incompatible_checksums_s_vs_0x78_2[] = "Incompatible checksums (%s vs 0x7829c19 = (branchtype, capped, comparator, extend, index, left, pos, right, span, strand, weight))";
static PyObject *__pyx_kp_u_;
static PyObject *__pyx_kp_u_0_212_145;
static PyObject *__pyx_kp_u_109_74_116;
static PyObject *__pyx_kp_u_128_130_133;
static PyObject *__pyx_kp_u_190_30_45;
static PyObject *__pyx_kp_u_28_117_188;
static PyObject *__pyx_n_u_A;
static PyObject *__pyx_n_u_ACGGG;
static PyObject *__pyx_n_u_AD;
static PyObject *__pyx_n_s_ASCII;
static PyObject *__pyx_n_u_ATAC;
static PyObject *__pyx_n_s_AcceptorPoint;
static PyObject *__pyx_n_s_AnnotationDataset;
static PyObject *__pyx_n_s_AnnotationDataset_generate_loci;
static PyObject *__pyx_n_s_AnnotationObject;
static PyObject *__pyx_n_s_BAMobject;
static PyObject *__pyx_n_u_BED;
static PyObject *__pyx_n_s_BP;
static PyObject *__pyx_n_s_BranchPoint;
static PyObject *__pyx_n_s_BranchpointArray;
static PyObject *__pyx_kp_s_Buffer_view_does_not_expose_stri;
static PyObject *__pyx_n_u_C;
static PyObject *__pyx_n_u_CCAC;
static PyObject *__pyx_n_s_COV;
static PyObject *__pyx_n_u_CTAC;
static PyObject *__pyx_n_u_CTGC;
static PyObject *__pyx_kp_u_C_2;
static PyObject *__pyx_kp_u_C_3;
static PyObject *__pyx_kp_u_C_ppm;
static PyObject *__pyx_kp_s_Can_only_create_a_buffer_that_is;
static PyObject *__pyx_kp_s_Cannot_assign_to_read_only_memor;
static PyObject *__pyx_kp_s_Cannot_create_writable_memory_vi;
static PyObject *__pyx_kp_s_Cannot_index_with_type_s;
static PyObject *__pyx_n_s_Counter;
static PyObject *__pyx_n_u_D;
static PyObject *__pyx_n_u_DA;
static PyObject *__pyx_n_s_DonorPoint;
static PyObject *__pyx_n_u_E;
static PyObject *__pyx_n_u_ELR;
static PyObject *__pyx_n_s_ELdata;
static PyObject *__pyx_n_u_ELdata;
static PyObject *__pyx_n_u_ES;
static PyObject *__pyx_kp_u_E_ppm;
static PyObject *__pyx_kp_u_E_reads;
static PyObject *__pyx_n_s_Ellipsis;
static PyObject *__pyx_kp_s_Empty_shape_tuple_for_cython_arr;
static PyObject *__pyx_n_s_EndPoint;
static PyObject *__pyx_kp_u_Format_string_allocated_too_shor;
static PyObject *__pyx_kp_u_Format_string_allocated_too_shor_2;
static PyObject *__pyx_n_u_G;
static PyObject *__pyx_n_u_GCAG;
static PyObject *__pyx_n_u_GFF;
static PyObject *__pyx_n_u_GFF3;
static PyObject *__pyx_n_u_GTAG;
static PyObject *__pyx_n_u_GTAT;
static PyObject *__pyx_n_u_GTF;
static PyObject *__pyx_n_u_GTGG;
static PyObject *__pyx_n_u_HI;
static PyObject *__pyx_n_u_ID;
static PyObject *__pyx_n_s_IUPACham;
static PyObject *__pyx_n_s_ImportError;
static PyObject *__pyx_kp_u_Importing;
static PyObject *__pyx_kp_s_Incompatible_checksums_s_vs_0x10;
static PyObject *__pyx_kp_s_Incompatible_checksums_s_vs_0x20;
static PyObject *__pyx_kp_s_Incompatible_checksums_s_vs_0x23;
static PyObject *__pyx_kp_s_Incompatible_checksums_s_vs_0x28;
static PyObject *__pyx_kp_s_Incompatible_checksums_s_vs_0x78;
static PyObject *__pyx_kp_s_Incompatible_checksums_s_vs_0x78_2;
static PyObject *__pyx_kp_s_Incompatible_checksums_s_vs_0x85;
static PyObject *__pyx_kp_s_Incompatible_checksums_s_vs_0xb0;
static PyObject *__pyx_kp_s_Incompatible_checksums_s_vs_0xc8;
static PyObject *__pyx_kp_s_Incompatible_checksums_s_vs_0xd4;
static PyObject *__pyx_kp_s_Incompatible_checksums_s_vs_0xdc;
static PyObject *__pyx_n_s_IndexError;
static PyObject *__pyx_kp_s_Indirect_dimensions_not_supporte;
static PyObject *__pyx_kp_s_Invalid_mode_expected_c_or_fortr;
static PyObject *__pyx_kp_s_Invalid_shape_in_axis_d_d;
static PyObject *__pyx_n_s_KeyError;
static PyObject *__pyx_n_u_MD;
static PyObject *__pyx_n_s_MemoryError;
static PyObject *__pyx_kp_s_MemoryView_of_r_at_0x_x;
static PyObject *__pyx_kp_s_MemoryView_of_r_object;
static PyObject *__pyx_n_u_N;
static PyObject *__pyx_n_u_NH;
static PyObject *__pyx_n_u_NM;
static PyObject *__pyx_kp_u_Non_native_byte_order_not_suppor;
static PyObject *__pyx_n_b_O;
static PyObject *__pyx_kp_u_OA;
static PyObject *__pyx_n_s_OrderedArray;
static PyObject *__pyx_kp_s_Out_of_bounds_on_buffer_access_a;
static PyObject *__pyx_n_u_Parent;
static PyObject *__pyx_n_s_PickleError;
static PyObject *__pyx_kp_u_RAN_OUT;
static PyObject *__pyx_n_s_RNAseqDataset;
static PyObject *__pyx_n_s_RNAseqMapping;
static PyObject *__pyx_n_u_RRRRRRRRRRRRRRR;
static PyObject *__pyx_n_s_RuntimeError;
static PyObject *__pyx_n_u_S;
static PyObject *__pyx_n_u_SE;
static PyObject *__pyx_kp_u_S_2;
static PyObject *__pyx_kp_u_S_3;
static PyObject *__pyx_kp_u_S_capped;
static PyObject *__pyx_kp_u_S_ppm;
static PyObject *__pyx_kp_u_S_reads;
static PyObject *__pyx_n_s_StartPoint;
static PyObject *__pyx_n_s_StopIteration;
static PyObject *__pyx_n_u_T;
static PyObject *__pyx_kp_u_TAG;
static PyObject *__pyx_n_u_TPM;
static PyObject *__pyx_n_s_TypeError;
static PyObject *__pyx_n_u_U;
static PyObject *__pyx_kp_s_Unable_to_convert_item_to_object;
static PyObject *__pyx_n_s_ValueError;
static PyObject *__pyx_n_s_View_MemoryView;
static PyObject *__pyx_n_u_X;
static PyObject *__pyx_n_u_XS;
static PyObject *__pyx_kp_u__10;
static PyObject *__pyx_kp_u__11;
static PyObject *__pyx_kp_u__12;
static PyObject *__pyx_kp_u__13;
static PyObject *__pyx_kp_u__14;
static PyObject *__pyx_kp_u__18;
static PyObject *__pyx_kp_u__19;
static PyObject *__pyx_kp_u__2;
static PyObject *__pyx_kp_u__20;
static PyObject *__pyx_kp_u__21;
static PyObject *__pyx_kp_u__23;
static PyObject *__pyx_kp_u__25;
static PyObject *__pyx_kp_u__26;
static PyObject *__pyx_kp_u__27;
static PyObject *__pyx_kp_u__28;
static PyObject *__pyx_kp_u__29;
static PyObject *__pyx_kp_u__3;
static PyObject *__pyx_kp_u__37;
static PyObject *__pyx_kp_u__39;
static PyObject *__pyx_kp_u__4;
static PyObject *__pyx_kp_u__49;
static PyObject *__pyx_n_u__5;
static PyObject *__pyx_kp_u__50;
static PyObject *__pyx_kp_u__6;
static PyObject *__pyx_kp_u__7;
static PyObject *__pyx_n_s__78;
static PyObject *__pyx_kp_u__8;
static PyObject *__pyx_kp_u__9;
static PyObject *__pyx_n_s_add;
static PyObject *__pyx_n_s_add_chrom;
static PyObject *__pyx_n_s_add_endpoint;
static PyObject *__pyx_n_s_add_read;
static PyObject *__pyx_n_s_add_read_from_BAM;
static PyObject *__pyx_n_s_add_read_from_BED;
static PyObject *__pyx_n_s_add_read_from_ELR;
static PyObject *__pyx_n_s_add_source;
static PyObject *__pyx_n_s_all;
static PyObject *__pyx_n_s_allocate_buffer;
static PyObject *__pyx_n_s_anno_string;
static PyObject *__pyx_n_s_anno_to_mapping_object;
static PyObject *__pyx_n_s_annotation_files;
static PyObject *__pyx_n_u_antisense_RNA;
static PyObject *__pyx_n_u_antisense_lncRNA;
static PyObject *__pyx_n_s_antisense_match;
static PyObject *__pyx_n_s_append;
static PyObject *__pyx_n_s_args;
static PyObject *__pyx_n_s_arr;
static PyObject *__pyx_n_s_array;
static PyObject *__pyx_n_s_array_length;
static PyObject *__pyx_n_s_array_to_blocks;
static PyObject *__pyx_n_s_as_string;
static PyObject *__pyx_n_s_ast;
static PyObject *__pyx_n_s_attr_format;
static PyObject *__pyx_n_s_attr_string;
static PyObject *__pyx_n_s_attributes;
static PyObject *__pyx_n_u_bam;
static PyObject *__pyx_n_s_bam_lines;
static PyObject *__pyx_n_s_base;
static PyObject *__pyx_n_u_bed;
static PyObject *__pyx_n_s_bed_colors;
static PyObject *__pyx_n_s_bed_line;
static PyObject *__pyx_n_s_block_end;
static PyObject *__pyx_n_s_block_start;
static PyObject *__pyx_n_s_bookend_core_cython_utils__fasta;
static PyObject *__pyx_n_s_bool;
static PyObject *__pyx_n_s_bp_from_counter;
static PyObject *__pyx_n_s_bp_typeorder;
static PyObject *__pyx_n_s_branchtype;
static PyObject *__pyx_n_s_c;
static PyObject *__pyx_n_u_c;
static PyObject *__pyx_n_s_cap_percent;
static PyObject *__pyx_n_u_cap_percent;
static PyObject *__pyx_n_s_capped;
static PyObject *__pyx_n_u_capped;
static PyObject *__pyx_kp_u_capped_2;
static PyObject *__pyx_n_s_capped_weight;
static PyObject *__pyx_n_u_child_key_gene;
static PyObject *__pyx_n_u_child_key_transcript;
static PyObject *__pyx_n_u_child_types;
static PyObject *__pyx_n_s_children;
static PyObject *__pyx_n_s_chrom;
static PyObject *__pyx_kp_u_chrom_2;
static PyObject *__pyx_n_s_chrom_array;
static PyObject *__pyx_n_s_chrom_lengths;
static PyObject *__pyx_kp_u_chrom_source_strand_ranges_splic;
static PyObject *__pyx_n_s_cigartuples;
static PyObject *__pyx_n_s_class;
static PyObject *__pyx_n_s_clean_array;
static PyObject *__pyx_n_s_cline_in_traceback;
static PyObject *__pyx_n_s_close;
static PyObject *__pyx_n_s_collections;
static PyObject *__pyx_n_s_comparator;
static PyObject *__pyx_n_s_confidence;
static PyObject *__pyx_n_u_confidence_threshold;
static PyObject *__pyx_n_s_config;
static PyObject *__pyx_n_s_config_defaults;
static PyObject *__pyx_n_s_config_dict;
static PyObject *__pyx_kp_s_contiguous_and_direct;
static PyObject *__pyx_kp_s_contiguous_and_indirect;
static PyObject *__pyx_n_s_copy;
static PyObject *__pyx_n_s_counter;
static PyObject *__pyx_n_u_cov;
static PyObject *__pyx_n_s_coverage;
static PyObject *__pyx_n_u_coverage;
static PyObject *__pyx_n_s_current;
static PyObject *__pyx_n_s_dataset;
static PyObject *__pyx_n_s_deepcopy;
static PyObject *__pyx_n_s_delete;
static PyObject *__pyx_n_s_dict;
static PyObject *__pyx_n_s_diff;
static PyObject *__pyx_n_s_distance_from_edge;
static PyObject *__pyx_n_s_dtype;
static PyObject *__pyx_n_s_dtype_is_object;
static PyObject *__pyx_n_s_dump_header;
static PyObject *__pyx_n_s_dumps;
static PyObject *__pyx_n_u_e;
static PyObject *__pyx_n_s_e_tag;
static PyObject *__pyx_n_u_e_tag;
static PyObject *__pyx_kp_u_e_tag_2;
static PyObject *__pyx_n_u_elr;
static PyObject *__pyx_n_s_encode;
static PyObject *__pyx_n_s_end_extend;
static PyObject *__pyx_n_u_end_seq;
static PyObject *__pyx_n_s_ends_clash;
static PyObject *__pyx_n_s_enumerate;
static PyObject *__pyx_n_s_error;
static PyObject *__pyx_n_s_error_rate;
static PyObject *__pyx_n_u_exon;
static PyObject *__pyx_n_s_extend;
static PyObject *__pyx_n_s_file_type;
static PyObject *__pyx_n_s_fileconn;
static PyObject *__pyx_n_s_filename;
static PyObject *__pyx_n_s_flags;
static PyObject *__pyx_n_s_float32;
static PyObject *__pyx_n_s_force;
static PyObject *__pyx_n_s_format;
static PyObject *__pyx_n_s_fortran;
static PyObject *__pyx_n_u_fortran;
static PyObject *__pyx_n_s_fu;
static PyObject *__pyx_n_s_full;
static PyObject *__pyx_n_s_gap;
static PyObject *__pyx_n_s_gaps;
static PyObject *__pyx_n_s_gaps_are_junctions;
static PyObject *__pyx_n_u_gene_id;
static PyObject *__pyx_n_s_generate_loci;
static PyObject *__pyx_n_s_generate_read;
static PyObject *__pyx_n_s_genome;
static PyObject *__pyx_n_s_genome_fasta;
static PyObject *__pyx_n_s_get;
static PyObject *__pyx_n_s_get_length;
static PyObject *__pyx_n_s_get_node_labels;
static PyObject *__pyx_n_s_get_reference_name;
static PyObject *__pyx_n_s_get_tag;
static PyObject *__pyx_n_s_get_transcript_fasta;
static PyObject *__pyx_n_s_getstate;
static PyObject *__pyx_n_u_gff;
static PyObject *__pyx_kp_u_gff3;
static PyObject *__pyx_kp_u_gff_2;
static PyObject *__pyx_n_s_gff_config;
static PyObject *__pyx_n_s_gff_defaults;
static PyObject *__pyx_kp_s_got_differing_extents_in_dimensi;
static PyObject *__pyx_n_u_gtf;
static PyObject *__pyx_kp_u_gtf_2;
static PyObject *__pyx_n_s_gtf_config;
static PyObject *__pyx_n_s_gtf_defaults;
static PyObject *__pyx_n_s_header;
static PyObject *__pyx_n_s_header_line;
static PyObject *__pyx_n_s_i;
static PyObject *__pyx_n_s_id;
static PyObject *__pyx_n_s_ignore_ends;
static PyObject *__pyx_n_s_ignore_source;
static PyObject *__pyx_n_s_import;
static PyObject *__pyx_n_s_import_annotation;
static PyObject *__pyx_n_s_import_genome;
static PyObject *__pyx_n_s_index;
static PyObject *__pyx_n_s_infer_ends;
static PyObject *__pyx_n_s_infer_starts;
static PyObject *__pyx_n_s_infer_unknown_branchpoints;
static PyObject *__pyx_n_s_init;
static PyObject *__pyx_n_s_init_2;
static PyObject *__pyx_n_s_input_data;
static PyObject *__pyx_n_s_input_lines;
static PyObject *__pyx_n_s_is_compatible;
static PyObject *__pyx_n_s_is_digit;
static PyObject *__pyx_n_s_is_gap;
static PyObject *__pyx_n_s_is_identical;
static PyObject *__pyx_n_s_is_paired;
static PyObject *__pyx_n_s_is_proper_pair;
static PyObject *__pyx_n_s_is_read1;
static PyObject *__pyx_n_s_is_reverse;
static PyObject *__pyx_n_s_is_secondary;
static PyObject *__pyx_n_s_is_supplementary;
static PyObject *__pyx_n_s_is_unmapped;
static PyObject *__pyx_n_s_isdigit;
static PyObject *__pyx_n_s_item;
static PyObject *__pyx_n_s_items;
static PyObject *__pyx_n_s_itemsize;
static PyObject *__pyx_kp_s_itemsize_0_for_cython_array;
static PyObject *__pyx_n_s_json;
static PyObject *__pyx_n_s_junctions;
static PyObject *__pyx_n_s_key;
static PyObject *__pyx_n_s_keys;
static PyObject *__pyx_n_s_l;
static PyObject *__pyx_n_s_label_len;
static PyObject *__pyx_n_s_label_type;
static PyObject *__pyx_n_s_last_chrom;
static PyObject *__pyx_n_s_last_index;
static PyObject *__pyx_n_s_last_read;
static PyObject *__pyx_n_s_leading_edge;
static PyObject *__pyx_n_s_left;
static PyObject *__pyx_n_s_leftmost;
static PyObject *__pyx_n_s_line;
static PyObject *__pyx_n_s_literal_eval;
static PyObject *__pyx_n_u_lnc_RNA;
static PyObject *__pyx_n_s_lower;
static PyObject *__pyx_n_u_mRNA;
static PyObject *__pyx_n_u_mRNA_TE_gene;
static PyObject *__pyx_n_s_main;
static PyObject *__pyx_n_s_max;
static PyObject *__pyx_n_s_max_cov;
static PyObject *__pyx_n_s_max_gap;
static PyObject *__pyx_n_s_maxgap;
static PyObject *__pyx_n_s_mdstring;
static PyObject *__pyx_n_s_memview;
static PyObject *__pyx_n_s_merge;
static PyObject *__pyx_n_u_miRNA;
static PyObject *__pyx_n_s_min_overhang;
static PyObject *__pyx_n_u_min_reps;
static PyObject *__pyx_n_s_minimum_proportion;
static PyObject *__pyx_n_u_minlen_loose;
static PyObject *__pyx_n_u_minlen_strict;
static PyObject *__pyx_n_u_mismatch_rate;
static PyObject *__pyx_n_s_mode;
static PyObject *__pyx_n_s_name;
static PyObject *__pyx_n_s_name_2;
static PyObject *__pyx_n_s_name_attr;
static PyObject *__pyx_n_s_namedtuple;
static PyObject *__pyx_n_u_ncRNA;
static PyObject *__pyx_kp_u_ndarray_is_not_C_contiguous;
static PyObject *__pyx_kp_u_ndarray_is_not_Fortran_contiguou;
static PyObject *__pyx_n_s_ndim;
static PyObject *__pyx_n_s_new;
static PyObject *__pyx_kp_s_no_default___reduce___due_to_non;
static PyObject *__pyx_n_s_np;
static PyObject *__pyx_n_s_nuc_to_int;
static PyObject *__pyx_n_s_number_of_reads;
static PyObject *__pyx_n_s_numpy;
static PyObject *__pyx_kp_u_numpy_core_multiarray_failed_to;
static PyObject *__pyx_kp_u_numpy_core_umath_failed_to_impor;
static PyObject *__pyx_n_s_obj;
static PyObject *__pyx_n_s_offset;
static PyObject *__pyx_n_s_open;
static PyObject *__pyx_n_s_ordered_values;
static PyObject *__pyx_n_s_other;
static PyObject *__pyx_n_s_overlap_range;
static PyObject *__pyx_n_s_overlaps;
static PyObject *__pyx_n_s_pack;
static PyObject *__pyx_n_s_parent;
static PyObject *__pyx_n_u_parent_key_gene;
static PyObject *__pyx_n_u_parent_key_transcript;
static PyObject *__pyx_n_u_parent_types;
static PyObject *__pyx_n_s_parse_MD_string;
static PyObject *__pyx_n_s_parse_attributes;
static PyObject *__pyx_n_s_percent_capped;
static PyObject *__pyx_n_s_pickle;
static PyObject *__pyx_n_s_pop;
static PyObject *__pyx_n_s_pop_read;
static PyObject *__pyx_n_s_pos;
static PyObject *__pyx_n_s_position;
static PyObject *__pyx_n_s_print;
static PyObject *__pyx_n_s_print_attributes;
static PyObject *__pyx_n_s_probe;
static PyObject *__pyx_n_u_pseudogenic_exon;
static PyObject *__pyx_n_u_pseudogenic_transcript;
static PyObject *__pyx_n_s_pyx_PickleError;
static PyObject *__pyx_n_s_pyx_checksum;
static PyObject *__pyx_n_s_pyx_getbuffer;
static PyObject *__pyx_n_s_pyx_result;
static PyObject *__pyx_n_s_pyx_state;
static PyObject *__pyx_n_s_pyx_type;
static PyObject *__pyx_n_s_pyx_unpickle_AcceptorPoint;
static PyObject *__pyx_n_s_pyx_unpickle_AnnotationDataset;
static PyObject *__pyx_n_s_pyx_unpickle_AnnotationObject;
static PyObject *__pyx_n_s_pyx_unpickle_BAMobject;
static PyObject *__pyx_n_s_pyx_unpickle_BranchPoint;
static PyObject *__pyx_n_s_pyx_unpickle_BranchpointArray;
static PyObject *__pyx_n_s_pyx_unpickle_DonorPoint;
static PyObject *__pyx_n_s_pyx_unpickle_EndPoint;
static PyObject *__pyx_n_s_pyx_unpickle_Enum;
static PyObject *__pyx_n_s_pyx_unpickle_OrderedArray;
static PyObject *__pyx_n_s_pyx_unpickle_RNAseqDataset;
static PyObject *__pyx_n_s_pyx_unpickle_RNAseqMapping;
static PyObject *__pyx_n_s_pyx_unpickle_StartPoint;
static PyObject *__pyx_n_s_pyx_vtable;
static PyObject *__pyx_n_s_query_name;
static PyObject *__pyx_n_s_query_sequence;
static PyObject *__pyx_n_s_r;
static PyObject *__pyx_n_u_r;
static PyObject *__pyx_n_u_rRNA;
static PyObject *__pyx_n_s_range;
static PyObject *__pyx_n_s_range_a;
static PyObject *__pyx_n_s_range_b;
static PyObject *__pyx_n_s_ranges;
static PyObject *__pyx_kp_u_ranges_2;
static PyObject *__pyx_n_s_rc;
static PyObject *__pyx_n_s_read;
static PyObject *__pyx_n_s_read_format;
static PyObject *__pyx_n_s_read_generator;
static PyObject *__pyx_n_s_reads;
static PyObject *__pyx_n_s_record_artifacts;
static PyObject *__pyx_n_s_reduce;
static PyObject *__pyx_n_s_reduce_cython;
static PyObject *__pyx_n_s_reduce_ex;
static PyObject *__pyx_n_s_reference;
static PyObject *__pyx_n_u_reference;
static PyObject *__pyx_n_s_reference_id;
static PyObject *__pyx_n_s_reference_name;
static PyObject *__pyx_n_s_reference_start;
static PyObject *__pyx_n_s_remove_branchpoint;
static PyObject *__pyx_n_s_replace;
static PyObject *__pyx_n_s_replace_2;
static PyObject *__pyx_n_s_reverse;
static PyObject *__pyx_n_s_right;
static PyObject *__pyx_n_s_rightmost;
static PyObject *__pyx_n_s_rnaseq_utils;
static PyObject *__pyx_kp_s_rnaseq_utils_pyx;
static PyObject *__pyx_n_s_round;
static PyObject *__pyx_n_s_rstrip;
static PyObject *__pyx_n_u_s;
static PyObject *__pyx_n_s_s_tag;
static PyObject *__pyx_n_u_s_tag;
static PyObject *__pyx_kp_u_s_tag_2;
static PyObject *__pyx_n_u_sam;
static PyObject *__pyx_n_s_score_column;
static PyObject *__pyx_n_s_secondary;
static PyObject *__pyx_n_s_send;
static PyObject *__pyx_n_s_sense_match;
static PyObject *__pyx_n_s_setstate;
static PyObject *__pyx_n_s_setstate_cython;
static PyObject *__pyx_n_s_shape;
static PyObject *__pyx_n_s_size;
static PyObject *__pyx_n_u_snRNA;
static PyObject *__pyx_n_u_snoRNA;
static PyObject *__pyx_n_s_sort;
static PyObject *__pyx_n_s_sorted;
static PyObject *__pyx_n_s_source;
static PyObject *__pyx_n_u_source;
static PyObject *__pyx_kp_u_source_2;
static PyObject *__pyx_n_s_source_array;
static PyObject *__pyx_n_s_source_string;
static PyObject *__pyx_n_s_span;
static PyObject *__pyx_kp_u_span_2;
static PyObject *__pyx_n_s_splice;
static PyObject *__pyx_kp_u_splice_2;
static PyObject *__pyx_n_s_splice_match;
static PyObject *__pyx_n_s_split;
static PyObject *__pyx_n_s_split_chunk;
static PyObject *__pyx_n_s_start;
static PyObject *__pyx_n_u_start_seq;
static PyObject *__pyx_n_s_step;
static PyObject *__pyx_n_s_stop;
static PyObject *__pyx_n_s_strand;
static PyObject *__pyx_kp_u_strand_2;
static PyObject *__pyx_n_u_stranded;
static PyObject *__pyx_kp_s_strided_and_direct;
static PyObject *__pyx_kp_s_strided_and_direct_or_indirect;
static PyObject *__pyx_kp_s_strided_and_indirect;
static PyObject *__pyx_kp_s_stringsource;
static PyObject *__pyx_n_s_struct;
static PyObject *__pyx_n_s_sum;
static PyObject *__pyx_n_u_tRNA;
static PyObject *__pyx_n_s_test;
static PyObject *__pyx_n_s_threshold;
static PyObject *__pyx_n_s_throw;
static PyObject *__pyx_n_u_transcript;
static PyObject *__pyx_n_u_transcript_id;
static PyObject *__pyx_n_u_ts;
static PyObject *__pyx_kp_s_unable_to_allocate_array_data;
static PyObject *__pyx_kp_s_unable_to_allocate_shape_and_str;
static PyObject *__pyx_kp_u_unknown_dtype_code_in_numpy_pxd;
static PyObject *__pyx_n_s_unpack;
static PyObject *__pyx_n_s_update;
static PyObject *__pyx_n_s_upper;
static PyObject *__pyx_n_s_use_attributes;
static PyObject *__pyx_n_s_values;
static PyObject *__pyx_n_u_verbose;
static PyObject *__pyx_n_s_was_digit;
static PyObject *__pyx_n_s_was_gap;
static PyObject *__pyx_n_s_weight;
static PyObject *__pyx_n_u_weight;
static PyObject *__pyx_kp_u_weight_2;
static PyObject *__pyx_n_s_where;
static PyObject *__pyx_n_s_write_as_bed;
static PyObject *__pyx_n_s_write_as_elr;
static PyObject *__pyx_n_s_write_as_gtf;
static PyObject *__pyx_n_s_zeros;
static PyObject *__pyx_n_s_zip;
static int __pyx_pf_13_rnaseq_utils_13RNAseqMapping___init__(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self, PyObject *__pyx_v_input_data, PyObject *__pyx_v_attributes); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13RNAseqMapping_2__eq__(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self, PyObject *__pyx_v_other); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13RNAseqMapping_4__gt__(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self, PyObject *__pyx_v_other); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13RNAseqMapping_6__ge__(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self, PyObject *__pyx_v_other); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13RNAseqMapping_8__lt__(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self, PyObject *__pyx_v_other); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13RNAseqMapping_10__le__(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self, PyObject *__pyx_v_other); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13RNAseqMapping_12__ne__(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self, PyObject *__pyx_v_other); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13RNAseqMapping_14__repr__(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self); /* proto */
static Py_ssize_t __pyx_pf_13_rnaseq_utils_13RNAseqMapping_16__len__(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13RNAseqMapping_18left(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13RNAseqMapping_20right(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13RNAseqMapping_22get_length(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13RNAseqMapping_24gaps(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13RNAseqMapping_26junctions(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13RNAseqMapping_28diff(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self, PyObject *__pyx_v_other); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13RNAseqMapping_30overlaps(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self, struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_other); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13RNAseqMapping_32overlap_range(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self, struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_other); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13RNAseqMapping_34ends_clash(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self, struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_other); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13RNAseqMapping_36splice_match(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self, struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_other, int __pyx_v_ignore_ends); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13RNAseqMapping_38antisense_match(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self, struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_other, int __pyx_v_end_extend); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13RNAseqMapping_40sense_match(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self, struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_other, int __pyx_v_end_extend); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13RNAseqMapping_42is_compatible(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self, struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_other, int __pyx_v_ignore_ends, int __pyx_v_ignore_source); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13RNAseqMapping_44is_identical(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self, struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_other); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13RNAseqMapping_46merge(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self, struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_other); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13RNAseqMapping_48get_node_labels(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self, PyObject *__pyx_v_record_artifacts); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13RNAseqMapping_50write_as_elr(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self, PyObject *__pyx_v_as_string, PyObject *__pyx_v_record_artifacts); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13RNAseqMapping_52write_as_bed(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self, PyObject *__pyx_v_chrom_array, PyObject *__pyx_v_source_array, PyObject *__pyx_v_as_string, PyObject *__pyx_v_score_column, PyObject *__pyx_v_record_artifacts, PyObject *__pyx_v_name_attr); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13RNAseqMapping_54write_as_gtf(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self, PyObject *__pyx_v_chrom_array, PyObject *__pyx_v_source); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13RNAseqMapping_56print_attributes(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self, PyObject *__pyx_v_format, PyObject *__pyx_v_full); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13RNAseqMapping_58write_as_json(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self, PyObject *__pyx_v_chrom_array, PyObject *__pyx_v_source_array); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13RNAseqMapping_5chrom___get__(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self); /* proto */
static int __pyx_pf_13_rnaseq_utils_13RNAseqMapping_5chrom_2__set__(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13RNAseqMapping_6source___get__(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self); /* proto */
static int __pyx_pf_13_rnaseq_utils_13RNAseqMapping_6source_2__set__(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13RNAseqMapping_6strand___get__(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self); /* proto */
static int __pyx_pf_13_rnaseq_utils_13RNAseqMapping_6strand_2__set__(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13RNAseqMapping_5s_len___get__(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self); /* proto */
static int __pyx_pf_13_rnaseq_utils_13RNAseqMapping_5s_len_2__set__(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13RNAseqMapping_5e_len___get__(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self); /* proto */
static int __pyx_pf_13_rnaseq_utils_13RNAseqMapping_5e_len_2__set__(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13RNAseqMapping_6ranges___get__(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self); /* proto */
static int __pyx_pf_13_rnaseq_utils_13RNAseqMapping_6ranges_2__set__(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static int __pyx_pf_13_rnaseq_utils_13RNAseqMapping_6ranges_4__del__(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13RNAseqMapping_6splice___get__(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self); /* proto */
static int __pyx_pf_13_rnaseq_utils_13RNAseqMapping_6splice_2__set__(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static int __pyx_pf_13_rnaseq_utils_13RNAseqMapping_6splice_4__del__(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13RNAseqMapping_5s_tag___get__(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self); /* proto */
static int __pyx_pf_13_rnaseq_utils_13RNAseqMapping_5s_tag_2__set__(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13RNAseqMapping_5e_tag___get__(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self); /* proto */
static int __pyx_pf_13_rnaseq_utils_13RNAseqMapping_5e_tag_2__set__(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13RNAseqMapping_6capped___get__(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self); /* proto */
static int __pyx_pf_13_rnaseq_utils_13RNAseqMapping_6capped_2__set__(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13RNAseqMapping_8complete___get__(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self); /* proto */
static int __pyx_pf_13_rnaseq_utils_13RNAseqMapping_8complete_2__set__(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13RNAseqMapping_12is_reference___get__(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self); /* proto */
static int __pyx_pf_13_rnaseq_utils_13RNAseqMapping_12is_reference_2__set__(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13RNAseqMapping_10attributes___get__(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self); /* proto */
static int __pyx_pf_13_rnaseq_utils_13RNAseqMapping_10attributes_2__set__(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static int __pyx_pf_13_rnaseq_utils_13RNAseqMapping_10attributes_4__del__(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13RNAseqMapping_4span___get__(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self); /* proto */
static int __pyx_pf_13_rnaseq_utils_13RNAseqMapping_4span_2__set__(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13RNAseqMapping_6weight___get__(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self); /* proto */
static int __pyx_pf_13_rnaseq_utils_13RNAseqMapping_6weight_2__set__(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13RNAseqMapping_8coverage___get__(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self); /* proto */
static int __pyx_pf_13_rnaseq_utils_13RNAseqMapping_8coverage_2__set__(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13RNAseqMapping_60__reduce_cython__(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13RNAseqMapping_62__setstate_cython__(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_self, PyObject *__pyx_v___pyx_state); /* proto */
static int __pyx_pf_13_rnaseq_utils_13RNAseqDataset___init__(struct __pyx_obj_13_rnaseq_utils_RNAseqDataset *__pyx_v_self, PyObject *__pyx_v_chrom_array, PyObject *__pyx_v_source_array, PyObject *__pyx_v_chrom_lengths, PyObject *__pyx_v_genome_fasta, PyObject *__pyx_v_config); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13RNAseqDataset_2add_source(struct __pyx_obj_13_rnaseq_utils_RNAseqDataset *__pyx_v_self, PyObject *__pyx_v_source_string); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13RNAseqDataset_4add_chrom(struct __pyx_obj_13_rnaseq_utils_RNAseqDataset *__pyx_v_self, PyObject *__pyx_v_chrom_string); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13RNAseqDataset_6add_read_from_BED(struct __pyx_obj_13_rnaseq_utils_RNAseqDataset *__pyx_v_self, PyObject *__pyx_v_bed_line, PyObject *__pyx_v_source_string, PyObject *__pyx_v_s_tag, PyObject *__pyx_v_e_tag, PyObject *__pyx_v_capped, PyObject *__pyx_v_gaps_are_junctions); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13RNAseqDataset_8add_read(struct __pyx_obj_13_rnaseq_utils_RNAseqDataset *__pyx_v_self, PyObject *__pyx_v_input_data); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13RNAseqDataset_10add_read_from_ELR(struct __pyx_obj_13_rnaseq_utils_RNAseqDataset *__pyx_v_self, PyObject *__pyx_v_elr_line); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13RNAseqDataset_12add_read_from_BAM(struct __pyx_obj_13_rnaseq_utils_RNAseqDataset *__pyx_v_self, PyObject *__pyx_v_bam_lines, int __pyx_v_ignore_ends, int __pyx_v_secondary); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13RNAseqDataset_14pop_read(struct __pyx_obj_13_rnaseq_utils_RNAseqDataset *__pyx_v_self, PyObject *__pyx_v_read_format, PyObject *__pyx_v_as_string); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13RNAseqDataset_16dump_header(struct __pyx_obj_13_rnaseq_utils_RNAseqDataset *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13RNAseqDataset_9read_list___get__(struct __pyx_obj_13_rnaseq_utils_RNAseqDataset *__pyx_v_self); /* proto */
static int __pyx_pf_13_rnaseq_utils_13RNAseqDataset_9read_list_2__set__(struct __pyx_obj_13_rnaseq_utils_RNAseqDataset *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static int __pyx_pf_13_rnaseq_utils_13RNAseqDataset_9read_list_4__del__(struct __pyx_obj_13_rnaseq_utils_RNAseqDataset *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13RNAseqDataset_11chrom_array___get__(struct __pyx_obj_13_rnaseq_utils_RNAseqDataset *__pyx_v_self); /* proto */
static int __pyx_pf_13_rnaseq_utils_13RNAseqDataset_11chrom_array_2__set__(struct __pyx_obj_13_rnaseq_utils_RNAseqDataset *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static int __pyx_pf_13_rnaseq_utils_13RNAseqDataset_11chrom_array_4__del__(struct __pyx_obj_13_rnaseq_utils_RNAseqDataset *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13RNAseqDataset_12source_array___get__(struct __pyx_obj_13_rnaseq_utils_RNAseqDataset *__pyx_v_self); /* proto */
static int __pyx_pf_13_rnaseq_utils_13RNAseqDataset_12source_array_2__set__(struct __pyx_obj_13_rnaseq_utils_RNAseqDataset *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static int __pyx_pf_13_rnaseq_utils_13RNAseqDataset_12source_array_4__del__(struct __pyx_obj_13_rnaseq_utils_RNAseqDataset *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13RNAseqDataset_13chrom_lengths___get__(struct __pyx_obj_13_rnaseq_utils_RNAseqDataset *__pyx_v_self); /* proto */
static int __pyx_pf_13_rnaseq_utils_13RNAseqDataset_13chrom_lengths_2__set__(struct __pyx_obj_13_rnaseq_utils_RNAseqDataset *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static int __pyx_pf_13_rnaseq_utils_13RNAseqDataset_13chrom_lengths_4__del__(struct __pyx_obj_13_rnaseq_utils_RNAseqDataset *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13RNAseqDataset_11chrom_index___get__(struct __pyx_obj_13_rnaseq_utils_RNAseqDataset *__pyx_v_self); /* proto */
static int __pyx_pf_13_rnaseq_utils_13RNAseqDataset_11chrom_index_2__set__(struct __pyx_obj_13_rnaseq_utils_RNAseqDataset *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13RNAseqDataset_12source_index___get__(struct __pyx_obj_13_rnaseq_utils_RNAseqDataset *__pyx_v_self); /* proto */
static int __pyx_pf_13_rnaseq_utils_13RNAseqDataset_12source_index_2__set__(struct __pyx_obj_13_rnaseq_utils_RNAseqDataset *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13RNAseqDataset_10chrom_dict___get__(struct __pyx_obj_13_rnaseq_utils_RNAseqDataset *__pyx_v_self); /* proto */
static int __pyx_pf_13_rnaseq_utils_13RNAseqDataset_10chrom_dict_2__set__(struct __pyx_obj_13_rnaseq_utils_RNAseqDataset *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static int __pyx_pf_13_rnaseq_utils_13RNAseqDataset_10chrom_dict_4__del__(struct __pyx_obj_13_rnaseq_utils_RNAseqDataset *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13RNAseqDataset_11source_dict___get__(struct __pyx_obj_13_rnaseq_utils_RNAseqDataset *__pyx_v_self); /* proto */
static int __pyx_pf_13_rnaseq_utils_13RNAseqDataset_11source_dict_2__set__(struct __pyx_obj_13_rnaseq_utils_RNAseqDataset *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static int __pyx_pf_13_rnaseq_utils_13RNAseqDataset_11source_dict_4__del__(struct __pyx_obj_13_rnaseq_utils_RNAseqDataset *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13RNAseqDataset_6config___get__(struct __pyx_obj_13_rnaseq_utils_RNAseqDataset *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13RNAseqDataset_6genome___get__(struct __pyx_obj_13_rnaseq_utils_RNAseqDataset *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13RNAseqDataset_11label_tally___get__(struct __pyx_obj_13_rnaseq_utils_RNAseqDataset *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13RNAseqDataset_5s_tag___get__(struct __pyx_obj_13_rnaseq_utils_RNAseqDataset *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13RNAseqDataset_5e_tag___get__(struct __pyx_obj_13_rnaseq_utils_RNAseqDataset *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13RNAseqDataset_6capped___get__(struct __pyx_obj_13_rnaseq_utils_RNAseqDataset *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13RNAseqDataset_8stranded___get__(struct __pyx_obj_13_rnaseq_utils_RNAseqDataset *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13RNAseqDataset_11ignore_ends___get__(struct __pyx_obj_13_rnaseq_utils_RNAseqDataset *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13RNAseqDataset_9start_seq___get__(struct __pyx_obj_13_rnaseq_utils_RNAseqDataset *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13RNAseqDataset_7end_seq___get__(struct __pyx_obj_13_rnaseq_utils_RNAseqDataset *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13RNAseqDataset_6minlen___get__(struct __pyx_obj_13_rnaseq_utils_RNAseqDataset *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13RNAseqDataset_13minlen_strict___get__(struct __pyx_obj_13_rnaseq_utils_RNAseqDataset *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13RNAseqDataset_12minlen_loose___get__(struct __pyx_obj_13_rnaseq_utils_RNAseqDataset *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13RNAseqDataset_13mismatch_rate___get__(struct __pyx_obj_13_rnaseq_utils_RNAseqDataset *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13RNAseqDataset_11start_array___get__(struct __pyx_obj_13_rnaseq_utils_RNAseqDataset *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13RNAseqDataset_9end_array___get__(struct __pyx_obj_13_rnaseq_utils_RNAseqDataset *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13RNAseqDataset_18__reduce_cython__(struct __pyx_obj_13_rnaseq_utils_RNAseqDataset *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13RNAseqDataset_20__setstate_cython__(struct __pyx_obj_13_rnaseq_utils_RNAseqDataset *__pyx_v_self, PyObject *__pyx_v___pyx_state); /* proto */
static int __pyx_pf_13_rnaseq_utils_16AnnotationObject___init__(struct __pyx_obj_13_rnaseq_utils_AnnotationObject *__pyx_v_self, PyObject *__pyx_v_anno_string, PyObject *__pyx_v_format, PyObject *__pyx_v_config_dict); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_16AnnotationObject_2parse_attributes(struct __pyx_obj_13_rnaseq_utils_AnnotationObject *__pyx_v_self, PyObject *__pyx_v_attr_string, PyObject *__pyx_v_attr_format); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_16AnnotationObject_4__eq__(struct __pyx_obj_13_rnaseq_utils_AnnotationObject *__pyx_v_self, PyObject *__pyx_v_other); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_16AnnotationObject_6__ne__(struct __pyx_obj_13_rnaseq_utils_AnnotationObject *__pyx_v_self, PyObject *__pyx_v_other); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_16AnnotationObject_8__gt__(struct __pyx_obj_13_rnaseq_utils_AnnotationObject *__pyx_v_self, PyObject *__pyx_v_other); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_16AnnotationObject_10__ge__(struct __pyx_obj_13_rnaseq_utils_AnnotationObject *__pyx_v_self, PyObject *__pyx_v_other); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_16AnnotationObject_12__lt__(struct __pyx_obj_13_rnaseq_utils_AnnotationObject *__pyx_v_self, PyObject *__pyx_v_other); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_16AnnotationObject_14__le__(struct __pyx_obj_13_rnaseq_utils_AnnotationObject *__pyx_v_self, PyObject *__pyx_v_other); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_16AnnotationObject_10attributes___get__(struct __pyx_obj_13_rnaseq_utils_AnnotationObject *__pyx_v_self); /* proto */
static int __pyx_pf_13_rnaseq_utils_16AnnotationObject_10attributes_2__set__(struct __pyx_obj_13_rnaseq_utils_AnnotationObject *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static int __pyx_pf_13_rnaseq_utils_16AnnotationObject_10attributes_4__del__(struct __pyx_obj_13_rnaseq_utils_AnnotationObject *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_16AnnotationObject_4keep___get__(struct __pyx_obj_13_rnaseq_utils_AnnotationObject *__pyx_v_self); /* proto */
static int __pyx_pf_13_rnaseq_utils_16AnnotationObject_4keep_2__set__(struct __pyx_obj_13_rnaseq_utils_AnnotationObject *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_16AnnotationObject_6parent___get__(struct __pyx_obj_13_rnaseq_utils_AnnotationObject *__pyx_v_self); /* proto */
static int __pyx_pf_13_rnaseq_utils_16AnnotationObject_6parent_2__set__(struct __pyx_obj_13_rnaseq_utils_AnnotationObject *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_16AnnotationObject_6format___get__(struct __pyx_obj_13_rnaseq_utils_AnnotationObject *__pyx_v_self); /* proto */
static int __pyx_pf_13_rnaseq_utils_16AnnotationObject_6format_2__set__(struct __pyx_obj_13_rnaseq_utils_AnnotationObject *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static int __pyx_pf_13_rnaseq_utils_16AnnotationObject_6format_4__del__(struct __pyx_obj_13_rnaseq_utils_AnnotationObject *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_16AnnotationObject_7gene_id___get__(struct __pyx_obj_13_rnaseq_utils_AnnotationObject *__pyx_v_self); /* proto */
static int __pyx_pf_13_rnaseq_utils_16AnnotationObject_7gene_id_2__set__(struct __pyx_obj_13_rnaseq_utils_AnnotationObject *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static int __pyx_pf_13_rnaseq_utils_16AnnotationObject_7gene_id_4__del__(struct __pyx_obj_13_rnaseq_utils_AnnotationObject *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_16AnnotationObject_13transcript_id___get__(struct __pyx_obj_13_rnaseq_utils_AnnotationObject *__pyx_v_self); /* proto */
static int __pyx_pf_13_rnaseq_utils_16AnnotationObject_13transcript_id_2__set__(struct __pyx_obj_13_rnaseq_utils_AnnotationObject *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static int __pyx_pf_13_rnaseq_utils_16AnnotationObject_13transcript_id_4__del__(struct __pyx_obj_13_rnaseq_utils_AnnotationObject *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_16AnnotationObject_5chrom___get__(struct __pyx_obj_13_rnaseq_utils_AnnotationObject *__pyx_v_self); /* proto */
static int __pyx_pf_13_rnaseq_utils_16AnnotationObject_5chrom_2__set__(struct __pyx_obj_13_rnaseq_utils_AnnotationObject *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static int __pyx_pf_13_rnaseq_utils_16AnnotationObject_5chrom_4__del__(struct __pyx_obj_13_rnaseq_utils_AnnotationObject *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_16AnnotationObject_6source___get__(struct __pyx_obj_13_rnaseq_utils_AnnotationObject *__pyx_v_self); /* proto */
static int __pyx_pf_13_rnaseq_utils_16AnnotationObject_6source_2__set__(struct __pyx_obj_13_rnaseq_utils_AnnotationObject *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static int __pyx_pf_13_rnaseq_utils_16AnnotationObject_6source_4__del__(struct __pyx_obj_13_rnaseq_utils_AnnotationObject *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_16AnnotationObject_9anno_type___get__(struct __pyx_obj_13_rnaseq_utils_AnnotationObject *__pyx_v_self); /* proto */
static int __pyx_pf_13_rnaseq_utils_16AnnotationObject_9anno_type_2__set__(struct __pyx_obj_13_rnaseq_utils_AnnotationObject *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static int __pyx_pf_13_rnaseq_utils_16AnnotationObject_9anno_type_4__del__(struct __pyx_obj_13_rnaseq_utils_AnnotationObject *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_16AnnotationObject_6strand___get__(struct __pyx_obj_13_rnaseq_utils_AnnotationObject *__pyx_v_self); /* proto */
static int __pyx_pf_13_rnaseq_utils_16AnnotationObject_6strand_2__set__(struct __pyx_obj_13_rnaseq_utils_AnnotationObject *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_16AnnotationObject_4span___get__(struct __pyx_obj_13_rnaseq_utils_AnnotationObject *__pyx_v_self); /* proto */
static int __pyx_pf_13_rnaseq_utils_16AnnotationObject_4span_2__set__(struct __pyx_obj_13_rnaseq_utils_AnnotationObject *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_16AnnotationObject_6fields___get__(struct __pyx_obj_13_rnaseq_utils_AnnotationObject *__pyx_v_self); /* proto */
static int __pyx_pf_13_rnaseq_utils_16AnnotationObject_6fields_2__set__(struct __pyx_obj_13_rnaseq_utils_AnnotationObject *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static int __pyx_pf_13_rnaseq_utils_16AnnotationObject_6fields_4__del__(struct __pyx_obj_13_rnaseq_utils_AnnotationObject *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_16AnnotationObject_16__reduce_cython__(struct __pyx_obj_13_rnaseq_utils_AnnotationObject *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_16AnnotationObject_18__setstate_cython__(struct __pyx_obj_13_rnaseq_utils_AnnotationObject *__pyx_v_self, PyObject *__pyx_v___pyx_state); /* proto */
static int __pyx_pf_13_rnaseq_utils_17AnnotationDataset___init__(struct __pyx_obj_13_rnaseq_utils_AnnotationDataset *__pyx_v_self, PyObject *__pyx_v_annotation_files, PyObject *__pyx_v_reference, PyObject *__pyx_v_genome_fasta, PyObject *__pyx_v_config, PyObject *__pyx_v_gtf_config, PyObject *__pyx_v_gff_config, PyObject *__pyx_v_confidence); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_17AnnotationDataset_2import_annotation(struct __pyx_obj_13_rnaseq_utils_AnnotationDataset *__pyx_v_self, PyObject *__pyx_v_filename, PyObject *__pyx_v_name); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_17AnnotationDataset_4get_transcript_fasta(struct __pyx_obj_13_rnaseq_utils_AnnotationDataset *__pyx_v_self, struct __pyx_obj_13_rnaseq_utils_RNAseqMapping *__pyx_v_transcript); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_17AnnotationDataset_6anno_to_mapping_object(struct __pyx_obj_13_rnaseq_utils_AnnotationDataset *__pyx_v_self, struct __pyx_obj_13_rnaseq_utils_AnnotationObject *__pyx_v_parent, PyObject *__pyx_v_children, int __pyx_v_source); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_17AnnotationDataset_8generate_loci(struct __pyx_obj_13_rnaseq_utils_AnnotationDataset *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_17AnnotationDataset_11annotations___get__(struct __pyx_obj_13_rnaseq_utils_AnnotationDataset *__pyx_v_self); /* proto */
static int __pyx_pf_13_rnaseq_utils_17AnnotationDataset_11annotations_2__set__(struct __pyx_obj_13_rnaseq_utils_AnnotationDataset *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static int __pyx_pf_13_rnaseq_utils_17AnnotationDataset_11annotations_4__del__(struct __pyx_obj_13_rnaseq_utils_AnnotationDataset *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_17AnnotationDataset_10gtf_config___get__(struct __pyx_obj_13_rnaseq_utils_AnnotationDataset *__pyx_v_self); /* proto */
static int __pyx_pf_13_rnaseq_utils_17AnnotationDataset_10gtf_config_2__set__(struct __pyx_obj_13_rnaseq_utils_AnnotationDataset *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static int __pyx_pf_13_rnaseq_utils_17AnnotationDataset_10gtf_config_4__del__(struct __pyx_obj_13_rnaseq_utils_AnnotationDataset *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_17AnnotationDataset_10gff_config___get__(struct __pyx_obj_13_rnaseq_utils_AnnotationDataset *__pyx_v_self); /* proto */
static int __pyx_pf_13_rnaseq_utils_17AnnotationDataset_10gff_config_2__set__(struct __pyx_obj_13_rnaseq_utils_AnnotationDataset *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static int __pyx_pf_13_rnaseq_utils_17AnnotationDataset_10gff_config_4__del__(struct __pyx_obj_13_rnaseq_utils_AnnotationDataset *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_17AnnotationDataset_9generator___get__(struct __pyx_obj_13_rnaseq_utils_AnnotationDataset *__pyx_v_self); /* proto */
static int __pyx_pf_13_rnaseq_utils_17AnnotationDataset_9generator_2__set__(struct __pyx_obj_13_rnaseq_utils_AnnotationDataset *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static int __pyx_pf_13_rnaseq_utils_17AnnotationDataset_9generator_4__del__(struct __pyx_obj_13_rnaseq_utils_AnnotationDataset *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_17AnnotationDataset_20number_of_assemblies___get__(struct __pyx_obj_13_rnaseq_utils_AnnotationDataset *__pyx_v_self); /* proto */
static int __pyx_pf_13_rnaseq_utils_17AnnotationDataset_20number_of_assemblies_2__set__(struct __pyx_obj_13_rnaseq_utils_AnnotationDataset *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_17AnnotationDataset_7counter___get__(struct __pyx_obj_13_rnaseq_utils_AnnotationDataset *__pyx_v_self); /* proto */
static int __pyx_pf_13_rnaseq_utils_17AnnotationDataset_7counter_2__set__(struct __pyx_obj_13_rnaseq_utils_AnnotationDataset *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_17AnnotationDataset_8min_reps___get__(struct __pyx_obj_13_rnaseq_utils_AnnotationDataset *__pyx_v_self); /* proto */
static int __pyx_pf_13_rnaseq_utils_17AnnotationDataset_8min_reps_2__set__(struct __pyx_obj_13_rnaseq_utils_AnnotationDataset *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_17AnnotationDataset_10confidence___get__(struct __pyx_obj_13_rnaseq_utils_AnnotationDataset *__pyx_v_self); /* proto */
static int __pyx_pf_13_rnaseq_utils_17AnnotationDataset_10confidence_2__set__(struct __pyx_obj_13_rnaseq_utils_AnnotationDataset *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_17AnnotationDataset_11cap_percent___get__(struct __pyx_obj_13_rnaseq_utils_AnnotationDataset *__pyx_v_self); /* proto */
static int __pyx_pf_13_rnaseq_utils_17AnnotationDataset_11cap_percent_2__set__(struct __pyx_obj_13_rnaseq_utils_AnnotationDataset *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_17AnnotationDataset_7verbose___get__(struct __pyx_obj_13_rnaseq_utils_AnnotationDataset *__pyx_v_self); /* proto */
static int __pyx_pf_13_rnaseq_utils_17AnnotationDataset_7verbose_2__set__(struct __pyx_obj_13_rnaseq_utils_AnnotationDataset *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_17AnnotationDataset_11__reduce_cython__(struct __pyx_obj_13_rnaseq_utils_AnnotationDataset *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_17AnnotationDataset_13__setstate_cython__(struct __pyx_obj_13_rnaseq_utils_AnnotationDataset *__pyx_v_self, PyObject *__pyx_v___pyx_state); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_array_to_blocks(CYTHON_UNUSED PyObject *__pyx_self, PyObject *__pyx_v_arr); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_3overlap_type(CYTHON_UNUSED PyObject *__pyx_self, PyObject *__pyx_v_range_a, PyObject *__pyx_v_range_b); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_5flatten(CYTHON_UNUSED PyObject *__pyx_self, PyObject *__pyx_v_list_of_lists); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_7collapse_blocks(CYTHON_UNUSED PyObject *__pyx_self, PyObject *__pyx_v_list_of_doubles); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_9elr_to_readobject(CYTHON_UNUSED PyObject *__pyx_self, PyObject *__pyx_v_elr_line); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_11range_of_reads(CYTHON_UNUSED PyObject *__pyx_self, PyObject *__pyx_v_reads); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13calculate_coverage(CYTHON_UNUSED PyObject *__pyx_self, PyObject *__pyx_v_reads, int __pyx_v_left, int __pyx_v_right); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_15split_chunk(CYTHON_UNUSED PyObject *__pyx_self, PyObject *__pyx_v_reads, float __pyx_v_minimum_proportion, int __pyx_v_max_gap); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_18get_flank(CYTHON_UNUSED PyObject *__pyx_self, PyObject *__pyx_v_genome, PyObject *__pyx_v_chrom, int __pyx_v_pos, int __pyx_v_strand, PyObject *__pyx_v_label_type, int __pyx_v_label_len); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_20parse_MD_string(CYTHON_UNUSED PyObject *__pyx_self, PyObject *__pyx_v_mdstring); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_23parse_SAM_CIGAR(CYTHON_UNUSED PyObject *__pyx_self, int __pyx_v_pos, PyObject *__pyx_v_cigartuples, PyObject *__pyx_v_mdstring, float __pyx_v_error_rate); /* proto */
static int __pyx_pf_13_rnaseq_utils_9BAMobject___init__(struct __pyx_obj_13_rnaseq_utils_BAMobject *__pyx_v_self, struct __pyx_obj_13_rnaseq_utils_RNAseqDataset *__pyx_v_dataset, PyObject *__pyx_v_input_lines, int __pyx_v_ignore_ends, int __pyx_v_secondary); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_9BAMobject_2generate_read(struct __pyx_obj_13_rnaseq_utils_BAMobject *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_9BAMobject_7dataset___get__(struct __pyx_obj_13_rnaseq_utils_BAMobject *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_9BAMobject_11input_lines___get__(struct __pyx_obj_13_rnaseq_utils_BAMobject *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_9BAMobject_11ignore_ends___get__(struct __pyx_obj_13_rnaseq_utils_BAMobject *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_9BAMobject_9secondary___get__(struct __pyx_obj_13_rnaseq_utils_BAMobject *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_9BAMobject_4__reduce_cython__(struct __pyx_obj_13_rnaseq_utils_BAMobject *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_9BAMobject_6__setstate_cython__(struct __pyx_obj_13_rnaseq_utils_BAMobject *__pyx_v_self, PyObject *__pyx_v___pyx_state); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_25read_generator(CYTHON_UNUSED PyObject *__pyx_self, PyObject *__pyx_v_fileconn, struct __pyx_obj_13_rnaseq_utils_RNAseqDataset *__pyx_v_dataset, PyObject *__pyx_v_file_type, int __pyx_v_max_gap); /* proto */
static int __pyx_pf_13_rnaseq_utils_16BranchpointArray___init__(struct __pyx_obj_13_rnaseq_utils_BranchpointArray *__pyx_v_self, int __pyx_v_leftmost, int __pyx_v_rightmost, PyObject *__pyx_v_reads, int __pyx_v_extend, int __pyx_v_end_extend, float __pyx_v_minimum_proportion, float __pyx_v_cap_percent, int __pyx_v_min_overhang, int __pyx_v_infer_starts, int __pyx_v_infer_ends, int __pyx_v_use_attributes); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_16BranchpointArray_2bp_from_counter(struct __pyx_obj_13_rnaseq_utils_BranchpointArray *__pyx_v_self, PyObject *__pyx_v_counter, PyObject *__pyx_v_branchtype, char __pyx_v_strand); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_16BranchpointArray_4distance_from_edge(struct __pyx_obj_13_rnaseq_utils_BranchpointArray *__pyx_v_self, int __pyx_v_pos, char __pyx_v_strand, PyObject *__pyx_v_branchtype); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_16BranchpointArray_6add_endpoint(struct __pyx_obj_13_rnaseq_utils_BranchpointArray *__pyx_v_self, struct __pyx_obj_13_rnaseq_utils_BranchPoint *__pyx_v_BP, PyObject *__pyx_v_force); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_16BranchpointArray_8infer_unknown_branchpoints(struct __pyx_obj_13_rnaseq_utils_BranchpointArray *__pyx_v_self, PyObject *__pyx_v_branchpoints); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_16BranchpointArray_10remove_branchpoint(struct __pyx_obj_13_rnaseq_utils_BranchpointArray *__pyx_v_self, PyObject *__pyx_v_strand, int __pyx_v_index); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_16BranchpointArray_6S_plus___get__(struct __pyx_obj_13_rnaseq_utils_BranchpointArray *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_16BranchpointArray_7S_minus___get__(struct __pyx_obj_13_rnaseq_utils_BranchpointArray *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_16BranchpointArray_6E_plus___get__(struct __pyx_obj_13_rnaseq_utils_BranchpointArray *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_16BranchpointArray_7E_minus___get__(struct __pyx_obj_13_rnaseq_utils_BranchpointArray *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_16BranchpointArray_6J_plus___get__(struct __pyx_obj_13_rnaseq_utils_BranchpointArray *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_16BranchpointArray_7J_minus___get__(struct __pyx_obj_13_rnaseq_utils_BranchpointArray *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_16BranchpointArray_8leftmost___get__(struct __pyx_obj_13_rnaseq_utils_BranchpointArray *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_16BranchpointArray_9rightmost___get__(struct __pyx_obj_13_rnaseq_utils_BranchpointArray *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_16BranchpointArray_6extend___get__(struct __pyx_obj_13_rnaseq_utils_BranchpointArray *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_16BranchpointArray_10end_extend___get__(struct __pyx_obj_13_rnaseq_utils_BranchpointArray *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_16BranchpointArray_6length___get__(struct __pyx_obj_13_rnaseq_utils_BranchpointArray *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_16BranchpointArray_12min_overhang___get__(struct __pyx_obj_13_rnaseq_utils_BranchpointArray *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_16BranchpointArray_12branchpoints___get__(struct __pyx_obj_13_rnaseq_utils_BranchpointArray *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_16BranchpointArray_6weight___get__(struct __pyx_obj_13_rnaseq_utils_BranchpointArray *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_16BranchpointArray_9threshold___get__(struct __pyx_obj_13_rnaseq_utils_BranchpointArray *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_16BranchpointArray_11cap_percent___get__(struct __pyx_obj_13_rnaseq_utils_BranchpointArray *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_16BranchpointArray_18minimum_proportion___get__(struct __pyx_obj_13_rnaseq_utils_BranchpointArray *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_16BranchpointArray_5depth___get__(struct __pyx_obj_13_rnaseq_utils_BranchpointArray *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_16BranchpointArray_7bp_plus___get__(struct __pyx_obj_13_rnaseq_utils_BranchpointArray *__pyx_v_self); /* proto */
static int __pyx_pf_13_rnaseq_utils_16BranchpointArray_7bp_plus_2__set__(struct __pyx_obj_13_rnaseq_utils_BranchpointArray *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static int __pyx_pf_13_rnaseq_utils_16BranchpointArray_7bp_plus_4__del__(struct __pyx_obj_13_rnaseq_utils_BranchpointArray *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_16BranchpointArray_8bp_minus___get__(struct __pyx_obj_13_rnaseq_utils_BranchpointArray *__pyx_v_self); /* proto */
static int __pyx_pf_13_rnaseq_utils_16BranchpointArray_8bp_minus_2__set__(struct __pyx_obj_13_rnaseq_utils_BranchpointArray *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static int __pyx_pf_13_rnaseq_utils_16BranchpointArray_8bp_minus_4__del__(struct __pyx_obj_13_rnaseq_utils_BranchpointArray *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_16BranchpointArray_12infer_starts___get__(struct __pyx_obj_13_rnaseq_utils_BranchpointArray *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_16BranchpointArray_10infer_ends___get__(struct __pyx_obj_13_rnaseq_utils_BranchpointArray *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_16BranchpointArray_14use_attributes___get__(struct __pyx_obj_13_rnaseq_utils_BranchpointArray *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_16BranchpointArray_12__reduce_cython__(struct __pyx_obj_13_rnaseq_utils_BranchpointArray *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_16BranchpointArray_14__setstate_cython__(struct __pyx_obj_13_rnaseq_utils_BranchpointArray *__pyx_v_self, PyObject *__pyx_v___pyx_state); /* proto */
static int __pyx_pf_13_rnaseq_utils_11BranchPoint___init__(struct __pyx_obj_13_rnaseq_utils_BranchPoint *__pyx_v_self, PyObject *__pyx_v_branchtype, char __pyx_v_strand, int __pyx_v_pos, float __pyx_v_weight); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_11BranchPoint_2percent_capped(struct __pyx_obj_13_rnaseq_utils_BranchPoint *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_11BranchPoint_4__repr__(struct __pyx_obj_13_rnaseq_utils_BranchPoint *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_11BranchPoint_6__eq__(struct __pyx_obj_13_rnaseq_utils_BranchPoint *__pyx_v_self, PyObject *__pyx_v_other); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_11BranchPoint_8__ne__(struct __pyx_obj_13_rnaseq_utils_BranchPoint *__pyx_v_self, PyObject *__pyx_v_other); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_11BranchPoint_10__gt__(struct __pyx_obj_13_rnaseq_utils_BranchPoint *__pyx_v_self, PyObject *__pyx_v_other); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_11BranchPoint_12__ge__(struct __pyx_obj_13_rnaseq_utils_BranchPoint *__pyx_v_self, PyObject *__pyx_v_other); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_11BranchPoint_14__lt__(struct __pyx_obj_13_rnaseq_utils_BranchPoint *__pyx_v_self, PyObject *__pyx_v_other); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_11BranchPoint_16__le__(struct __pyx_obj_13_rnaseq_utils_BranchPoint *__pyx_v_self, PyObject *__pyx_v_other); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_11BranchPoint_18write_as_bed(struct __pyx_obj_13_rnaseq_utils_BranchPoint *__pyx_v_self, PyObject *__pyx_v_chrom); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_11BranchPoint_10branchtype___get__(struct __pyx_obj_13_rnaseq_utils_BranchPoint *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_11BranchPoint_6strand___get__(struct __pyx_obj_13_rnaseq_utils_BranchPoint *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_11BranchPoint_3pos___get__(struct __pyx_obj_13_rnaseq_utils_BranchPoint *__pyx_v_self); /* proto */
static int __pyx_pf_13_rnaseq_utils_11BranchPoint_3pos_2__set__(struct __pyx_obj_13_rnaseq_utils_BranchPoint *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_11BranchPoint_5index___get__(struct __pyx_obj_13_rnaseq_utils_BranchPoint *__pyx_v_self); /* proto */
static int __pyx_pf_13_rnaseq_utils_11BranchPoint_5index_2__set__(struct __pyx_obj_13_rnaseq_utils_BranchPoint *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_11BranchPoint_4left___get__(struct __pyx_obj_13_rnaseq_utils_BranchPoint *__pyx_v_self); /* proto */
static int __pyx_pf_13_rnaseq_utils_11BranchPoint_4left_2__set__(struct __pyx_obj_13_rnaseq_utils_BranchPoint *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_11BranchPoint_5right___get__(struct __pyx_obj_13_rnaseq_utils_BranchPoint *__pyx_v_self); /* proto */
static int __pyx_pf_13_rnaseq_utils_11BranchPoint_5right_2__set__(struct __pyx_obj_13_rnaseq_utils_BranchPoint *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_11BranchPoint_6weight___get__(struct __pyx_obj_13_rnaseq_utils_BranchPoint *__pyx_v_self); /* proto */
static int __pyx_pf_13_rnaseq_utils_11BranchPoint_6weight_2__set__(struct __pyx_obj_13_rnaseq_utils_BranchPoint *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_11BranchPoint_10comparator___get__(struct __pyx_obj_13_rnaseq_utils_BranchPoint *__pyx_v_self); /* proto */
static int __pyx_pf_13_rnaseq_utils_11BranchPoint_10comparator_2__set__(struct __pyx_obj_13_rnaseq_utils_BranchPoint *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_11BranchPoint_20__reduce_cython__(struct __pyx_obj_13_rnaseq_utils_BranchPoint *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_11BranchPoint_22__setstate_cython__(struct __pyx_obj_13_rnaseq_utils_BranchPoint *__pyx_v_self, PyObject *__pyx_v___pyx_state); /* proto */
static int __pyx_pf_13_rnaseq_utils_10StartPoint___init__(struct __pyx_obj_13_rnaseq_utils_StartPoint *__pyx_v_self, PyObject *__pyx_v_strand, PyObject *__pyx_v_pos, PyObject *__pyx_v_weight, PyObject *__pyx_v_extend, PyObject *__pyx_v_capped_weight); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_10StartPoint_2percent_capped(struct __pyx_obj_13_rnaseq_utils_StartPoint *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_10StartPoint_4merge(struct __pyx_obj_13_rnaseq_utils_StartPoint *__pyx_v_self, struct __pyx_obj_13_rnaseq_utils_StartPoint *__pyx_v_other); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_10StartPoint_6extend___get__(struct __pyx_obj_13_rnaseq_utils_StartPoint *__pyx_v_self); /* proto */
static int __pyx_pf_13_rnaseq_utils_10StartPoint_6extend_2__set__(struct __pyx_obj_13_rnaseq_utils_StartPoint *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_10StartPoint_4span___get__(struct __pyx_obj_13_rnaseq_utils_StartPoint *__pyx_v_self); /* proto */
static int __pyx_pf_13_rnaseq_utils_10StartPoint_4span_2__set__(struct __pyx_obj_13_rnaseq_utils_StartPoint *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static int __pyx_pf_13_rnaseq_utils_10StartPoint_4span_4__del__(struct __pyx_obj_13_rnaseq_utils_StartPoint *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_10StartPoint_6capped___get__(struct __pyx_obj_13_rnaseq_utils_StartPoint *__pyx_v_self); /* proto */
static int __pyx_pf_13_rnaseq_utils_10StartPoint_6capped_2__set__(struct __pyx_obj_13_rnaseq_utils_StartPoint *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_10StartPoint_6__reduce_cython__(struct __pyx_obj_13_rnaseq_utils_StartPoint *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_10StartPoint_8__setstate_cython__(struct __pyx_obj_13_rnaseq_utils_StartPoint *__pyx_v_self, PyObject *__pyx_v___pyx_state); /* proto */
static int __pyx_pf_13_rnaseq_utils_8EndPoint___init__(struct __pyx_obj_13_rnaseq_utils_EndPoint *__pyx_v_self, PyObject *__pyx_v_strand, PyObject *__pyx_v_pos, PyObject *__pyx_v_weight, PyObject *__pyx_v_extend); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_8EndPoint_2merge(struct __pyx_obj_13_rnaseq_utils_EndPoint *__pyx_v_self, struct __pyx_obj_13_rnaseq_utils_EndPoint *__pyx_v_other); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_8EndPoint_6extend___get__(struct __pyx_obj_13_rnaseq_utils_EndPoint *__pyx_v_self); /* proto */
static int __pyx_pf_13_rnaseq_utils_8EndPoint_6extend_2__set__(struct __pyx_obj_13_rnaseq_utils_EndPoint *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_8EndPoint_4span___get__(struct __pyx_obj_13_rnaseq_utils_EndPoint *__pyx_v_self); /* proto */
static int __pyx_pf_13_rnaseq_utils_8EndPoint_4span_2__set__(struct __pyx_obj_13_rnaseq_utils_EndPoint *__pyx_v_self, PyObject *__pyx_v_value); /* proto */
static int __pyx_pf_13_rnaseq_utils_8EndPoint_4span_4__del__(struct __pyx_obj_13_rnaseq_utils_EndPoint *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_8EndPoint_4__reduce_cython__(struct __pyx_obj_13_rnaseq_utils_EndPoint *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_8EndPoint_6__setstate_cython__(struct __pyx_obj_13_rnaseq_utils_EndPoint *__pyx_v_self, PyObject *__pyx_v___pyx_state); /* proto */
static int __pyx_pf_13_rnaseq_utils_10DonorPoint___init__(struct __pyx_obj_13_rnaseq_utils_DonorPoint *__pyx_v_self, PyObject *__pyx_v_strand, PyObject *__pyx_v_pos, PyObject *__pyx_v_weight); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_10DonorPoint_2__reduce_cython__(struct __pyx_obj_13_rnaseq_utils_DonorPoint *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_10DonorPoint_4__setstate_cython__(struct __pyx_obj_13_rnaseq_utils_DonorPoint *__pyx_v_self, PyObject *__pyx_v___pyx_state); /* proto */
static int __pyx_pf_13_rnaseq_utils_13AcceptorPoint___init__(struct __pyx_obj_13_rnaseq_utils_AcceptorPoint *__pyx_v_self, PyObject *__pyx_v_strand, PyObject *__pyx_v_pos, PyObject *__pyx_v_weight); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13AcceptorPoint_2__reduce_cython__(struct __pyx_obj_13_rnaseq_utils_AcceptorPoint *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_13AcceptorPoint_4__setstate_cython__(struct __pyx_obj_13_rnaseq_utils_AcceptorPoint *__pyx_v_self, PyObject *__pyx_v___pyx_state); /* proto */
static int __pyx_pf_13_rnaseq_utils_12OrderedArray___init__(struct __pyx_obj_13_rnaseq_utils_OrderedArray *__pyx_v_self, PyObject *__pyx_v_array); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_12OrderedArray_2__repr__(struct __pyx_obj_13_rnaseq_utils_OrderedArray *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_12OrderedArray_4ordered_index(struct __pyx_obj_13_rnaseq_utils_OrderedArray *__pyx_v_self, PyObject *__pyx_v_position); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_12OrderedArray_6ordered_values(struct __pyx_obj_13_rnaseq_utils_OrderedArray *__pyx_v_self, PyObject *__pyx_v_position); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_12OrderedArray_8__iter__(struct __pyx_obj_13_rnaseq_utils_OrderedArray *__pyx_v_self); /* proto */
static Py_ssize_t __pyx_pf_13_rnaseq_utils_12OrderedArray_10__len__(struct __pyx_obj_13_rnaseq_utils_OrderedArray *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_12OrderedArray_12__add__(PyObject *__pyx_v_self, PyObject *__pyx_v_other); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_12OrderedArray_14add(struct __pyx_obj_13_rnaseq_utils_OrderedArray *__pyx_v_self, PyObject *__pyx_v_item, PyObject *__pyx_v_init); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_12OrderedArray_16delete(struct __pyx_obj_13_rnaseq_utils_OrderedArray *__pyx_v_self, PyObject *__pyx_v_index); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_12OrderedArray_18add_list(struct __pyx_obj_13_rnaseq_utils_OrderedArray *__pyx_v_self, PyObject *__pyx_v_list_to_add); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_12OrderedArray_20probe(struct __pyx_obj_13_rnaseq_utils_OrderedArray *__pyx_v_self, PyObject *__pyx_v_item, PyObject *__pyx_v_init); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_12OrderedArray_1n___get__(struct __pyx_obj_13_rnaseq_utils_OrderedArray *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_12OrderedArray_13ordered_array___get__(struct __pyx_obj_13_rnaseq_utils_OrderedArray *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_12OrderedArray_22__reduce_cython__(struct __pyx_obj_13_rnaseq_utils_OrderedArray *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_12OrderedArray_24__setstate_cython__(struct __pyx_obj_13_rnaseq_utils_OrderedArray *__pyx_v_self, PyObject *__pyx_v___pyx_state); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_28get_max_deltas(CYTHON_UNUSED PyObject *__pyx_self, PyArrayObject *__pyx_v_array, float __pyx_v_offset); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_30get_gaps(CYTHON_UNUSED PyObject *__pyx_self, PyArrayObject *__pyx_v_array, int __pyx_v_maxgap, PyObject *__pyx_v_threshold); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_32__pyx_unpickle_RNAseqMapping(CYTHON_UNUSED PyObject *__pyx_self, PyObject *__pyx_v___pyx_type, long __pyx_v___pyx_checksum, PyObject *__pyx_v___pyx_state); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_34__pyx_unpickle_RNAseqDataset(CYTHON_UNUSED PyObject *__pyx_self, PyObject *__pyx_v___pyx_type, long __pyx_v___pyx_checksum, PyObject *__pyx_v___pyx_state); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_36__pyx_unpickle_AnnotationObject(CYTHON_UNUSED PyObject *__pyx_self, PyObject *__pyx_v___pyx_type, long __pyx_v___pyx_checksum, PyObject *__pyx_v___pyx_state); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_38__pyx_unpickle_AnnotationDataset(CYTHON_UNUSED PyObject *__pyx_self, PyObject *__pyx_v___pyx_type, long __pyx_v___pyx_checksum, PyObject *__pyx_v___pyx_state); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_40__pyx_unpickle_BAMobject(CYTHON_UNUSED PyObject *__pyx_self, PyObject *__pyx_v___pyx_type, long __pyx_v___pyx_checksum, PyObject *__pyx_v___pyx_state); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_42__pyx_unpickle_BranchpointArray(CYTHON_UNUSED PyObject *__pyx_self, PyObject *__pyx_v___pyx_type, long __pyx_v___pyx_checksum, PyObject *__pyx_v___pyx_state); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_44__pyx_unpickle_BranchPoint(CYTHON_UNUSED PyObject *__pyx_self, PyObject *__pyx_v___pyx_type, long __pyx_v___pyx_checksum, PyObject *__pyx_v___pyx_state); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_46__pyx_unpickle_StartPoint(CYTHON_UNUSED PyObject *__pyx_self, PyObject *__pyx_v___pyx_type, long __pyx_v___pyx_checksum, PyObject *__pyx_v___pyx_state); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_48__pyx_unpickle_EndPoint(CYTHON_UNUSED PyObject *__pyx_self, PyObject *__pyx_v___pyx_type, long __pyx_v___pyx_checksum, PyObject *__pyx_v___pyx_state); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_50__pyx_unpickle_DonorPoint(CYTHON_UNUSED PyObject *__pyx_self, PyObject *__pyx_v___pyx_type, long __pyx_v___pyx_checksum, PyObject *__pyx_v___pyx_state); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_52__pyx_unpickle_AcceptorPoint(CYTHON_UNUSED PyObject *__pyx_self, PyObject *__pyx_v___pyx_type, long __pyx_v___pyx_checksum, PyObject *__pyx_v___pyx_state); /* proto */
static PyObject *__pyx_pf_13_rnaseq_utils_54__pyx_unpickle_OrderedArray(CYTHON_UNUSED PyObject *__pyx_self, PyObject *__pyx_v___pyx_type, long __pyx_v___pyx_checksum, PyObject *__pyx_v___pyx_state); /* proto */
static int __pyx_pf_7cpython_5array_5array___getbuffer__(arrayobject *__pyx_v_self, Py_buffer *__pyx_v_info, CYTHON_UNUSED int __pyx_v_flags); /* proto */
static void __pyx_pf_7cpython_5array_5array_2__releasebuffer__(CYTHON_UNUSED arrayobject *__pyx_v_self, Py_buffer *__pyx_v_info); /* proto */
static int __pyx_pf_5numpy_7ndarray___getbuffer__(PyArrayObject *__pyx_v_self, Py_buffer *__pyx_v_info, int __pyx_v_flags); /* proto */
static void __pyx_pf_5numpy_7ndarray_2__releasebuffer__(PyArrayObject *__pyx_v_self, Py_buffer *__pyx_v_info); /* proto */
static int __pyx_array___pyx_pf_15View_dot_MemoryView_5array___cinit__(struct __pyx_array_obj *__pyx_v_self, PyObject *__pyx_v_shape, Py_ssize_t __pyx_v_itemsize, PyObject *__pyx_v_format, PyObject *__pyx_v_mode, int __pyx_v_allocate_buffer); /* proto */
static int __pyx_array___pyx_pf_15View_dot_MemoryView_5array_2__getbuffer__(struct __pyx_array_obj *__pyx_v_self, Py_buffer *__pyx_v_info, int __pyx_v_flags); /* proto */
static void __pyx_array___pyx_pf_15View_dot_MemoryView_5array_4__dealloc__(struct __pyx_array_obj *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_15View_dot_MemoryView_5array_7memview___get__(struct __pyx_array_obj *__pyx_v_self); /* proto */
static Py_ssize_t __pyx_array___pyx_pf_15View_dot_MemoryView_5array_6__len__(struct __pyx_array_obj *__pyx_v_self); /* proto */
static PyObject *__pyx_array___pyx_pf_15View_dot_MemoryView_5array_8__getattr__(struct __pyx_array_obj *__pyx_v_self, PyObject *__pyx_v_attr); /* proto */
static PyObject *__pyx_array___pyx_pf_15View_dot_MemoryView_5array_10__getitem__(struct __pyx_array_obj *__pyx_v_self, PyObject *__pyx_v_item); /* proto */
static int __pyx_array___pyx_pf_15View_dot_MemoryView_5array_12__setitem__(struct __pyx_array_obj *__pyx_v_self, PyObject *__pyx_v_item, PyObject *__pyx_v_value); /* proto */
static PyObject *__pyx_pf___pyx_array___reduce_cython__(CYTHON_UNUSED struct __pyx_array_obj *__pyx_v_self); /* proto */
static PyObject *__pyx_pf___pyx_array_2__setstate_cython__(CYTHON_UNUSED struct __pyx_array_obj *__pyx_v_self, CYTHON_UNUSED PyObject *__pyx_v___pyx_state); /* proto */
static int __pyx_MemviewEnum___pyx_pf_15View_dot_MemoryView_4Enum___init__(struct __pyx_MemviewEnum_obj *__pyx_v_self, PyObject *__pyx_v_name); /* proto */
static PyObject *__pyx_MemviewEnum___pyx_pf_15View_dot_MemoryView_4Enum_2__repr__(struct __pyx_MemviewEnum_obj *__pyx_v_self); /* proto */
static PyObject *__pyx_pf___pyx_MemviewEnum___reduce_cython__(struct __pyx_MemviewEnum_obj *__pyx_v_self); /* proto */
static PyObject *__pyx_pf___pyx_MemviewEnum_2__setstate_cython__(struct __pyx_MemviewEnum_obj *__pyx_v_self, PyObject *__pyx_v___pyx_state); /* proto */
static int __pyx_memoryview___pyx_pf_15View_dot_MemoryView_10memoryview___cinit__(struct __pyx_memoryview_obj *__pyx_v_self, PyObject *__pyx_v_obj, int __pyx_v_flags, int __pyx_v_dtype_is_object); /* proto */
static void __pyx_memoryview___pyx_pf_15View_dot_MemoryView_10memoryview_2__dealloc__(struct __pyx_memoryview_obj *__pyx_v_self); /* proto */
static PyObject *__pyx_memoryview___pyx_pf_15View_dot_MemoryView_10memoryview_4__getitem__(struct __pyx_memoryview_obj *__pyx_v_self, PyObject *__pyx_v_index); /* proto */
static int __pyx_memoryview___pyx_pf_15View_dot_MemoryView_10memoryview_6__setitem__(struct __pyx_memoryview_obj *__pyx_v_self, PyObject *__pyx_v_index, PyObject *__pyx_v_value); /* proto */
static int __pyx_memoryview___pyx_pf_15View_dot_MemoryView_10memoryview_8__getbuffer__(struct __pyx_memoryview_obj *__pyx_v_self, Py_buffer *__pyx_v_info, int __pyx_v_flags); /* proto */
static PyObject *__pyx_pf_15View_dot_MemoryView_10memoryview_1T___get__(struct __pyx_memoryview_obj *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_15View_dot_MemoryView_10memoryview_4base___get__(struct __pyx_memoryview_obj *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_15View_dot_MemoryView_10memoryview_5shape___get__(struct __pyx_memoryview_obj *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_15View_dot_MemoryView_10memoryview_7strides___get__(struct __pyx_memoryview_obj *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_15View_dot_MemoryView_10memoryview_10suboffsets___get__(struct __pyx_memoryview_obj *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_15View_dot_MemoryView_10memoryview_4ndim___get__(struct __pyx_memoryview_obj *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_15View_dot_MemoryView_10memoryview_8itemsize___get__(struct __pyx_memoryview_obj *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_15View_dot_MemoryView_10memoryview_6nbytes___get__(struct __pyx_memoryview_obj *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_15View_dot_MemoryView_10memoryview_4size___get__(struct __pyx_memoryview_obj *__pyx_v_self); /* proto */
static Py_ssize_t __pyx_memoryview___pyx_pf_15View_dot_MemoryView_10memoryview_10__len__(struct __pyx_memoryview_obj *__pyx_v_self); /* proto */
static PyObject *__pyx_memoryview___pyx_pf_15View_dot_MemoryView_10memoryview_12__repr__(struct __pyx_memoryview_obj *__pyx_v_self); /* proto */
static PyObject *__pyx_memoryview___pyx_pf_15View_dot_MemoryView_10memoryview_14__str__(struct __pyx_memoryview_obj *__pyx_v_self); /* proto */
static PyObject *__pyx_memoryview___pyx_pf_15View_dot_MemoryView_10memoryview_16is_c_contig(struct __pyx_memoryview_obj *__pyx_v_self); /* proto */
static PyObject *__pyx_memoryview___pyx_pf_15View_dot_MemoryView_10memoryview_18is_f_contig(struct __pyx_memoryview_obj *__pyx_v_self); /* proto */
static PyObject *__pyx_memoryview___pyx_pf_15View_dot_MemoryView_10memoryview_20copy(struct __pyx_memoryview_obj *__pyx_v_self); /* proto */
static PyObject *__pyx_memoryview___pyx_pf_15View_dot_MemoryView_10memoryview_22copy_fortran(struct __pyx_memoryview_obj *__pyx_v_self); /* proto */
static PyObject *__pyx_pf___pyx_memoryview___reduce_cython__(CYTHON_UNUSED struct __pyx_memoryview_obj *__pyx_v_self); /* proto */
static PyObject *__pyx_pf___pyx_memoryview_2__setstate_cython__(CYTHON_UNUSED struct __pyx_memoryview_obj *__pyx_v_self, CYTHON_UNUSED PyObject *__pyx_v___pyx_state); /* proto */
static void __pyx_memoryviewslice___pyx_pf_15View_dot_MemoryView_16_memoryviewslice___dealloc__(struct __pyx_memoryviewslice_obj *__pyx_v_self); /* proto */
static PyObject *__pyx_pf_15View_dot_MemoryView_16_memoryviewslice_4base___get__(struct __pyx_memoryviewslice_obj *__pyx_v_self); /* proto */
static PyObject *__pyx_pf___pyx_memoryviewslice___reduce_cython__(CYTHON_UNUSED struct __pyx_memoryviewslice_obj *__pyx_v_self); /* proto */
static PyObject *__pyx_pf___pyx_memoryviewslice_2__setstate_cython__(CYTHON_UNUSED struct __pyx_memoryviewslice_obj *__pyx_v_self, CYTHON_UNUSED PyObject *__pyx_v___pyx_state); /* proto */
static PyObject *__pyx_pf_15View_dot_MemoryView___pyx_unpickle_Enum(CYTHON_UNUSED PyObject *__pyx_self, PyObject *__pyx_v___pyx_type, long __pyx_v___pyx_checksum, PyObject *__pyx_v___pyx_state); /* proto */
static PyObject *__pyx_tp_new_13_rnaseq_utils_RNAseqMapping(PyTypeObject *t, PyObject *a, PyObject *k); /*proto*/
static PyObject *__pyx_tp_new_13_rnaseq_utils_RNAseqDataset(PyTypeObject *t, PyObject *a, PyObject *k); /*proto*/
static PyObject *__pyx_tp_new_13_rnaseq_utils_AnnotationObject(PyTypeObject *t, PyObject *a, PyObject *k); /*proto*/
static PyObject *__pyx_tp_new_13_rnaseq_utils_AnnotationDataset(PyTypeObject *t, PyObject *a, PyObject *k); /*proto*/
static PyObject *__pyx_tp_new_13_rnaseq_utils_BAMobject(PyTypeObject *t, PyObject *a, PyObject *k); /*proto*/
static PyObject *__pyx_tp_new_13_rnaseq_utils_BranchpointArray(PyTypeObject *t, PyObject *a, PyObject *k); /*proto*/
static PyObject *__pyx_tp_new_13_rnaseq_utils_BranchPoint(PyTypeObject *t, PyObject *a, PyObject *k); /*proto*/
static PyObject *__pyx_tp_new_13_rnaseq_utils_StartPoint(PyTypeObject *t, PyObject *a, PyObject *k); /*proto*/
static PyObject *__pyx_tp_new_13_rnaseq_utils_EndPoint(PyTypeObject *t, PyObject *a, PyObject *k); /*proto*/
static PyObject *__pyx_tp_new_13_rnaseq_utils_DonorPoint(PyTypeObject *t, PyObject *a, PyObject *k); /*proto*/
static PyObject *__pyx_tp_new_13_rnaseq_utils_AcceptorPoint(PyTypeObject *t, PyObject *a, PyObject *k); /*proto*/
static PyObject *__pyx_tp_new_13_rnaseq_utils_OrderedArray(PyTypeObject *t, PyObject *a, PyObject *k); /*proto*/
static PyObject *__pyx_tp_new_13_rnaseq_utils___pyx_scope_struct__generate_loci(PyTypeObject *t, PyObject *a, PyObject *k); /*proto*/
static PyObject *__pyx_tp_new_13_rnaseq_utils___pyx_scope_struct_1_array_to_blocks(PyTypeObject *t, PyObject *a, PyObject *k); /*proto*/
static PyObject *__pyx_tp_new_13_rnaseq_utils___pyx_scope_struct_2_split_chunk(PyTypeObject *t, PyObject *a, PyObject *k); /*proto*/
static PyObject *__pyx_tp_new_13_rnaseq_utils___pyx_scope_struct_3_parse_MD_string(PyTypeObject *t, PyObject *a, PyObject *k); /*proto*/
static PyObject *__pyx_tp_new_13_rnaseq_utils___pyx_scope_struct_4_read_generator(PyTypeObject *t, PyObject *a, PyObject *k); /*proto*/
static PyObject *__pyx_tp_new_array(PyTypeObject *t, PyObject *a, PyObject *k); /*proto*/
static PyObject *__pyx_tp_new_Enum(PyTypeObject *t, PyObject *a, PyObject *k); /*proto*/
static PyObject *__pyx_tp_new_memoryview(PyTypeObject *t, PyObject *a, PyObject *k); /*proto*/
static PyObject *__pyx_tp_new__memoryviewslice(PyTypeObject *t, PyObject *a, PyObject *k); /*proto*/
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static __Pyx_CachedCFunction __pyx_umethod_PyDict_Type_keys = {0, &__pyx_n_s_keys, 0, 0, 0};
static __Pyx_CachedCFunction __pyx_umethod_PyDict_Type_values = {0, &__pyx_n_s_values, 0, 0, 0};
static __Pyx_CachedCFunction __pyx_umethod_PyList_Type_pop = {0, &__pyx_n_s_pop, 0, 0, 0};
static __Pyx_CachedCFunction __pyx_umethod_PySet_Type_update = {0, &__pyx_n_s_update, 0, 0, 0};
static __Pyx_CachedCFunction __pyx_umethod_PyUnicode_Type_rstrip = {0, &__pyx_n_s_rstrip, 0, 0, 0};
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static PyObject *__pyx_float_0_2;
static PyObject *__pyx_float_0_5;
static PyObject *__pyx_float_0_05;
static PyObject *__pyx_int_0;
static PyObject *__pyx_int_1;
static PyObject *__pyx_int_2;
static PyObject *__pyx_int_3;
static PyObject *__pyx_int_9;
static PyObject *__pyx_int_20;
static PyObject *__pyx_int_25;
static PyObject *__pyx_int_17757456;
static PyObject *__pyx_int_34018211;
static PyObject *__pyx_int_36934390;
static PyObject *__pyx_int_42059956;
static PyObject *__pyx_int_126000153;
static PyObject *__pyx_int_126708629;
static PyObject *__pyx_int_139781740;
static PyObject *__pyx_int_184977713;
static PyObject *__pyx_int_210534182;
static PyObject *__pyx_int_222355364;
static PyObject *__pyx_int_231340267;
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static PyObject *__pyx_k__31;
static PyObject *__pyx_k__32;
static PyObject *__pyx_k__51;
static PyObject *__pyx_k__52;
static PyObject *__pyx_slice__24;
static PyObject *__pyx_slice__38;
static PyObject *__pyx_slice__41;
static PyObject *__pyx_slice__74;
static PyObject *__pyx_tuple__15;
static PyObject *__pyx_tuple__16;
static PyObject *__pyx_tuple__17;
static PyObject *__pyx_tuple__33;
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 */
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 */
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 */
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 *         for i in range(input_len):
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 */
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 *         for i in range(input_len):             # <<<<<<<<<<<<<<
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 *         for i in range(input_len):
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 */
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 *     if isinstance(memview, _memoryviewslice):             # <<<<<<<<<<<<<<
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 *     if isinstance(memview, _memoryviewslice):
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 *                                     memviewsliceobj.to_dtype_func,
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 *                                     memviewsliceobj.to_object_func,
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 */
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 *             new_ndim += 1
 * 
 *     if isinstance(memview, _memoryviewslice):             # <<<<<<<<<<<<<<
 *         return memoryview_fromslice(dst, new_ndim,
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 */
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 *                                     memview.dtype_is_object)
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 */
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 * 
 * 
 */
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 *                                     memview.dtype_is_object)
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 */
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 * 
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 *     cdef int new_ndim = 0, suboffset_dim = -1, dim
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 */

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/* "View.MemoryView":807
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 *         __Pyx_memviewslice *dst,
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 */

static int __pyx_memoryview_slice_memviewslice(__Pyx_memviewslice *__pyx_v_dst, Py_ssize_t __pyx_v_shape, Py_ssize_t __pyx_v_stride, Py_ssize_t __pyx_v_suboffset, int __pyx_v_dim, int __pyx_v_new_ndim, int *__pyx_v_suboffset_dim, Py_ssize_t __pyx_v_start, Py_ssize_t __pyx_v_stop, Py_ssize_t __pyx_v_step, int __pyx_v_have_start, int __pyx_v_have_stop, int __pyx_v_have_step, int __pyx_v_is_slice) {
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 *     if not is_slice:             # <<<<<<<<<<<<<<
 * 
 *         if start < 0:
 */
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 *         if start < 0:             # <<<<<<<<<<<<<<
 *             start += shape
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 */
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 * 
 *         if start < 0:
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 *         if not 0 <= start < shape:
 *             _err_dim(IndexError, "Index out of bounds (axis %d)", dim)
 */
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 *     if not is_slice:
 * 
 *         if start < 0:             # <<<<<<<<<<<<<<
 *             start += shape
 *         if not 0 <= start < shape:
 */
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 *         if start < 0:
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 *             _err_dim(IndexError, "Index out of bounds (axis %d)", dim)
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 */
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      /* "View.MemoryView":832
 *             start += shape
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 *     else:
 * 
 */
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      /* "View.MemoryView":831
 *         if start < 0:
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 *             _err_dim(IndexError, "Index out of bounds (axis %d)", dim)
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 */
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 * 
 *     if not is_slice:             # <<<<<<<<<<<<<<
 * 
 *         if start < 0:
 */
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  /* "View.MemoryView":835
 *     else:
 * 
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 * 
 *         if have_step and step == 0:
 */
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 * 
 *         if have_step and step == 0:             # <<<<<<<<<<<<<<
 *             _err_dim(ValueError, "Step may not be zero (axis %d)", dim)
 * 
 */
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      /* "View.MemoryView":838
 * 
 *         if have_step and step == 0:
 *             _err_dim(ValueError, "Step may not be zero (axis %d)", dim)             # <<<<<<<<<<<<<<
 * 
 * 
 */
      __pyx_t_3 = __pyx_memoryview_err_dim(__pyx_builtin_ValueError, ((char *)"Step may not be zero (axis %d)"), __pyx_v_dim); if (unlikely(__pyx_t_3 == ((int)-1))) __PYX_ERR(1, 838, __pyx_L1_error)

      /* "View.MemoryView":837
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 * 
 *         if have_step and step == 0:             # <<<<<<<<<<<<<<
 *             _err_dim(ValueError, "Step may not be zero (axis %d)", dim)
 * 
 */
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    /* "View.MemoryView":841
 * 
 * 
 *         if have_start:             # <<<<<<<<<<<<<<
 *             if start < 0:
 *                 start += shape
 */
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      /* "View.MemoryView":842
 * 
 *         if have_start:
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 *                 start += shape
 *                 if start < 0:
 */
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        /* "View.MemoryView":843
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 *                 if start < 0:
 *                     start = 0
 */
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        /* "View.MemoryView":844
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 *                     start = 0
 *             elif start >= shape:
 */
        __pyx_t_2 = ((__pyx_v_start < 0) != 0);
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          /* "View.MemoryView":845
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 *                     start = 0             # <<<<<<<<<<<<<<
 *             elif start >= shape:
 *                 if negative_step:
 */
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          /* "View.MemoryView":844
 *             if start < 0:
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 *                     start = 0
 *             elif start >= shape:
 */
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        /* "View.MemoryView":842
 * 
 *         if have_start:
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 *                 start += shape
 *                 if start < 0:
 */
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      /* "View.MemoryView":846
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 *             elif start >= shape:             # <<<<<<<<<<<<<<
 *                 if negative_step:
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 */
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        /* "View.MemoryView":847
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 *                 if negative_step:             # <<<<<<<<<<<<<<
 *                     start = shape - 1
 *                 else:
 */
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          /* "View.MemoryView":848
 *             elif start >= shape:
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 *                     start = shape - 1             # <<<<<<<<<<<<<<
 *                 else:
 *                     start = shape
 */
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          /* "View.MemoryView":847
 *                     start = 0
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 *                 if negative_step:             # <<<<<<<<<<<<<<
 *                     start = shape - 1
 *                 else:
 */
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        /* "View.MemoryView":850
 *                     start = shape - 1
 *                 else:
 *                     start = shape             # <<<<<<<<<<<<<<
 *         else:
 *             if negative_step:
 */
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        /* "View.MemoryView":846
 *                 if start < 0:
 *                     start = 0
 *             elif start >= shape:             # <<<<<<<<<<<<<<
 *                 if negative_step:
 *                     start = shape - 1
 */
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      /* "View.MemoryView":841
 * 
 * 
 *         if have_start:             # <<<<<<<<<<<<<<
 *             if start < 0:
 *                 start += shape
 */
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    /* "View.MemoryView":852
 *                     start = shape
 *         else:
 *             if negative_step:             # <<<<<<<<<<<<<<
 *                 start = shape - 1
 *             else:
 */
    /*else*/ {
      __pyx_t_2 = (__pyx_v_negative_step != 0);
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        /* "View.MemoryView":853
 *         else:
 *             if negative_step:
 *                 start = shape - 1             # <<<<<<<<<<<<<<
 *             else:
 *                 start = 0
 */
        __pyx_v_start = (__pyx_v_shape - 1);

        /* "View.MemoryView":852
 *                     start = shape
 *         else:
 *             if negative_step:             # <<<<<<<<<<<<<<
 *                 start = shape - 1
 *             else:
 */
        goto __pyx_L15;
      }

      /* "View.MemoryView":855
 *                 start = shape - 1
 *             else:
 *                 start = 0             # <<<<<<<<<<<<<<
 * 
 *         if have_stop:
 */
      /*else*/ {
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    /* "View.MemoryView":857
 *                 start = 0
 * 
 *         if have_stop:             # <<<<<<<<<<<<<<
 *             if stop < 0:
 *                 stop += shape
 */
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      /* "View.MemoryView":858
 * 
 *         if have_stop:
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 *                 stop += shape
 *                 if stop < 0:
 */
      __pyx_t_2 = ((__pyx_v_stop < 0) != 0);
      if (__pyx_t_2) {

        /* "View.MemoryView":859
 *         if have_stop:
 *             if stop < 0:
 *                 stop += shape             # <<<<<<<<<<<<<<
 *                 if stop < 0:
 *                     stop = 0
 */
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 *             if stop < 0:
 *                 stop += shape
 *                 if stop < 0:             # <<<<<<<<<<<<<<
 *                     stop = 0
 *             elif stop > shape:
 */
        __pyx_t_2 = ((__pyx_v_stop < 0) != 0);
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          /* "View.MemoryView":861
 *                 stop += shape
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 *                     stop = 0             # <<<<<<<<<<<<<<
 *             elif stop > shape:
 *                 stop = shape
 */
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          /* "View.MemoryView":860
 *             if stop < 0:
 *                 stop += shape
 *                 if stop < 0:             # <<<<<<<<<<<<<<
 *                     stop = 0
 *             elif stop > shape:
 */
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        /* "View.MemoryView":858
 * 
 *         if have_stop:
 *             if stop < 0:             # <<<<<<<<<<<<<<
 *                 stop += shape
 *                 if stop < 0:
 */
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 *             elif stop > shape:             # <<<<<<<<<<<<<<
 *                 stop = shape
 *         else:
 */
      __pyx_t_2 = ((__pyx_v_stop > __pyx_v_shape) != 0);
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        /* "View.MemoryView":863
 *                     stop = 0
 *             elif stop > shape:
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 *         else:
 *             if negative_step:
 */
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 *         else:
 */
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 * 
 *         if have_stop:             # <<<<<<<<<<<<<<
 *             if stop < 0:
 *                 stop += shape
 */
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 *                 stop = shape
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 * cdef Py_ssize_t abs_py_ssize_t(Py_ssize_t arg) nogil:             # <<<<<<<<<<<<<<
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/* "View.MemoryView":1116
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 */
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 *     for i in range(ndim - 1, -1, -1):
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 */
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 *     for i in range(ndim):
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 *     for i in range(ndim):             # <<<<<<<<<<<<<<
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    /* "View.MemoryView":1130
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 *     for i in range(ndim):
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 */
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/* "View.MemoryView":1140
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static void _copy_strided_to_strided(char *__pyx_v_src_data, Py_ssize_t *__pyx_v_src_strides, char *__pyx_v_dst_data, Py_ssize_t *__pyx_v_dst_strides, Py_ssize_t *__pyx_v_src_shape, Py_ssize_t *__pyx_v_dst_shape, int __pyx_v_ndim, size_t __pyx_v_itemsize) {
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  Py_ssize_t __pyx_t_6;

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  /* "View.MemoryView":1148
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  /* "View.MemoryView":1149
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 *     if ndim == 1:
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        /* "View.MemoryView":1158
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        /* "View.MemoryView":1159
 *            for i in range(dst_extent):
 *                memcpy(dst_data, src_data, itemsize)
 *                src_data += src_stride             # <<<<<<<<<<<<<<
 *                dst_data += dst_stride
 *     else:
 */
        __pyx_v_src_data = (__pyx_v_src_data + __pyx_v_src_stride);

        /* "View.MemoryView":1160
 *                memcpy(dst_data, src_data, itemsize)
 *                src_data += src_stride
 *                dst_data += dst_stride             # <<<<<<<<<<<<<<
 *     else:
 *         for i in range(dst_extent):
 */
        __pyx_v_dst_data = (__pyx_v_dst_data + __pyx_v_dst_stride);
      }
    }
    __pyx_L4:;

    /* "View.MemoryView":1152
 *     cdef Py_ssize_t dst_stride = dst_strides[0]
 * 
 *     if ndim == 1:             # <<<<<<<<<<<<<<
 *        if (src_stride > 0 and dst_stride > 0 and
 *            <size_t> src_stride == itemsize == <size_t> dst_stride):
 */
    goto __pyx_L3;
  }

  /* "View.MemoryView":1162
 *                dst_data += dst_stride
 *     else:
 *         for i in range(dst_extent):             # <<<<<<<<<<<<<<
 *             _copy_strided_to_strided(src_data, src_strides + 1,
 *                                      dst_data, dst_strides + 1,
 */
  /*else*/ {
    __pyx_t_4 = __pyx_v_dst_extent;
    __pyx_t_5 = __pyx_t_4;
    for (__pyx_t_6 = 0; __pyx_t_6 < __pyx_t_5; __pyx_t_6+=1) {
      __pyx_v_i = __pyx_t_6;

      /* "View.MemoryView":1163
 *     else:
 *         for i in range(dst_extent):
 *             _copy_strided_to_strided(src_data, src_strides + 1,             # <<<<<<<<<<<<<<
 *                                      dst_data, dst_strides + 1,
 *                                      src_shape + 1, dst_shape + 1,
 */
      _copy_strided_to_strided(__pyx_v_src_data, (__pyx_v_src_strides + 1), __pyx_v_dst_data, (__pyx_v_dst_strides + 1), (__pyx_v_src_shape + 1), (__pyx_v_dst_shape + 1), (__pyx_v_ndim - 1), __pyx_v_itemsize);

      /* "View.MemoryView":1167
 *                                      src_shape + 1, dst_shape + 1,
 *                                      ndim - 1, itemsize)
 *             src_data += src_stride             # <<<<<<<<<<<<<<
 *             dst_data += dst_stride
 * 
 */
      __pyx_v_src_data = (__pyx_v_src_data + __pyx_v_src_stride);

      /* "View.MemoryView":1168
 *                                      ndim - 1, itemsize)
 *             src_data += src_stride
 *             dst_data += dst_stride             # <<<<<<<<<<<<<<
 * 
 * cdef void copy_strided_to_strided(__Pyx_memviewslice *src,
 */
      __pyx_v_dst_data = (__pyx_v_dst_data + __pyx_v_dst_stride);
    }
  }
  __pyx_L3:;

  /* "View.MemoryView":1140
 * 
 * @cython.cdivision(True)
 * cdef void _copy_strided_to_strided(char *src_data, Py_ssize_t *src_strides,             # <<<<<<<<<<<<<<
 *                                    char *dst_data, Py_ssize_t *dst_strides,
 *                                    Py_ssize_t *src_shape, Py_ssize_t *dst_shape,
 */

  /* function exit code */
}

/* "View.MemoryView":1170
 *             dst_data += dst_stride
 * 
 * cdef void copy_strided_to_strided(__Pyx_memviewslice *src,             # <<<<<<<<<<<<<<
 *                                   __Pyx_memviewslice *dst,
 *                                   int ndim, size_t itemsize) nogil:
 */

static void copy_strided_to_strided(__Pyx_memviewslice *__pyx_v_src, __Pyx_memviewslice *__pyx_v_dst, int __pyx_v_ndim, size_t __pyx_v_itemsize) {

  /* "View.MemoryView":1173
 *                                   __Pyx_memviewslice *dst,
 *                                   int ndim, size_t itemsize) nogil:
 *     _copy_strided_to_strided(src.data, src.strides, dst.data, dst.strides,             # <<<<<<<<<<<<<<
 *                              src.shape, dst.shape, ndim, itemsize)
 * 
 */
  _copy_strided_to_strided(__pyx_v_src->data, __pyx_v_src->strides, __pyx_v_dst->data, __pyx_v_dst->strides, __pyx_v_src->shape, __pyx_v_dst->shape, __pyx_v_ndim, __pyx_v_itemsize);

  /* "View.MemoryView":1170
 *             dst_data += dst_stride
 * 
 * cdef void copy_strided_to_strided(__Pyx_memviewslice *src,             # <<<<<<<<<<<<<<
 *                                   __Pyx_memviewslice *dst,
 *                                   int ndim, size_t itemsize) nogil:
 */

  /* function exit code */
}

/* "View.MemoryView":1177
 * 
 * @cname('__pyx_memoryview_slice_get_size')
 * cdef Py_ssize_t slice_get_size(__Pyx_memviewslice *src, int ndim) nogil:             # <<<<<<<<<<<<<<
 *     "Return the size of the memory occupied by the slice in number of bytes"
 *     cdef int i
 */

static Py_ssize_t __pyx_memoryview_slice_get_size(__Pyx_memviewslice *__pyx_v_src, int __pyx_v_ndim) {
  int __pyx_v_i;
  Py_ssize_t __pyx_v_size;
  Py_ssize_t __pyx_r;
  Py_ssize_t __pyx_t_1;
  int __pyx_t_2;
  int __pyx_t_3;
  int __pyx_t_4;

  /* "View.MemoryView":1180
 *     "Return the size of the memory occupied by the slice in number of bytes"
 *     cdef int i
 *     cdef Py_ssize_t size = src.memview.view.itemsize             # <<<<<<<<<<<<<<
 * 
 *     for i in range(ndim):
 */
  __pyx_t_1 = __pyx_v_src->memview->view.itemsize;
  __pyx_v_size = __pyx_t_1;

  /* "View.MemoryView":1182
 *     cdef Py_ssize_t size = src.memview.view.itemsize
 * 
 *     for i in range(ndim):             # <<<<<<<<<<<<<<
 *         size *= src.shape[i]
 * 
 */
  __pyx_t_2 = __pyx_v_ndim;
  __pyx_t_3 = __pyx_t_2;
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    __pyx_v_i = __pyx_t_4;

    /* "View.MemoryView":1183
 * 
 *     for i in range(ndim):
 *         size *= src.shape[i]             # <<<<<<<<<<<<<<
 * 
 *     return size
 */
    __pyx_v_size = (__pyx_v_size * (__pyx_v_src->shape[__pyx_v_i]));
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  /* "View.MemoryView":1185
 *         size *= src.shape[i]
 * 
 *     return size             # <<<<<<<<<<<<<<
 * 
 * @cname('__pyx_fill_contig_strides_array')
 */
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  /* "View.MemoryView":1177
 * 
 * @cname('__pyx_memoryview_slice_get_size')
 * cdef Py_ssize_t slice_get_size(__Pyx_memviewslice *src, int ndim) nogil:             # <<<<<<<<<<<<<<
 *     "Return the size of the memory occupied by the slice in number of bytes"
 *     cdef int i
 */

  /* function exit code */
  __pyx_L0:;
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}

/* "View.MemoryView":1188
 * 
 * @cname('__pyx_fill_contig_strides_array')
 * cdef Py_ssize_t fill_contig_strides_array(             # <<<<<<<<<<<<<<
 *                 Py_ssize_t *shape, Py_ssize_t *strides, Py_ssize_t stride,
 *                 int ndim, char order) nogil:
 */

static Py_ssize_t __pyx_fill_contig_strides_array(Py_ssize_t *__pyx_v_shape, Py_ssize_t *__pyx_v_strides, Py_ssize_t __pyx_v_stride, int __pyx_v_ndim, char __pyx_v_order) {
  int __pyx_v_idx;
  Py_ssize_t __pyx_r;
  int __pyx_t_1;
  int __pyx_t_2;
  int __pyx_t_3;
  int __pyx_t_4;

  /* "View.MemoryView":1197
 *     cdef int idx
 * 
 *     if order == 'F':             # <<<<<<<<<<<<<<
 *         for idx in range(ndim):
 *             strides[idx] = stride
 */
  __pyx_t_1 = ((__pyx_v_order == 'F') != 0);
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    /* "View.MemoryView":1198
 * 
 *     if order == 'F':
 *         for idx in range(ndim):             # <<<<<<<<<<<<<<
 *             strides[idx] = stride
 *             stride = stride * shape[idx]
 */
    __pyx_t_2 = __pyx_v_ndim;
    __pyx_t_3 = __pyx_t_2;
    for (__pyx_t_4 = 0; __pyx_t_4 < __pyx_t_3; __pyx_t_4+=1) {
      __pyx_v_idx = __pyx_t_4;

      /* "View.MemoryView":1199
 *     if order == 'F':
 *         for idx in range(ndim):
 *             strides[idx] = stride             # <<<<<<<<<<<<<<
 *             stride = stride * shape[idx]
 *     else:
 */
      (__pyx_v_strides[__pyx_v_idx]) = __pyx_v_stride;

      /* "View.MemoryView":1200
 *         for idx in range(ndim):
 *             strides[idx] = stride
 *             stride = stride * shape[idx]             # <<<<<<<<<<<<<<
 *     else:
 *         for idx in range(ndim - 1, -1, -1):
 */
      __pyx_v_stride = (__pyx_v_stride * (__pyx_v_shape[__pyx_v_idx]));
    }

    /* "View.MemoryView":1197
 *     cdef int idx
 * 
 *     if order == 'F':             # <<<<<<<<<<<<<<
 *         for idx in range(ndim):
 *             strides[idx] = stride
 */
    goto __pyx_L3;
  }

  /* "View.MemoryView":1202
 *             stride = stride * shape[idx]
 *     else:
 *         for idx in range(ndim - 1, -1, -1):             # <<<<<<<<<<<<<<
 *             strides[idx] = stride
 *             stride = stride * shape[idx]
 */
  /*else*/ {
    for (__pyx_t_2 = (__pyx_v_ndim - 1); __pyx_t_2 > -1; __pyx_t_2-=1) {
      __pyx_v_idx = __pyx_t_2;

      /* "View.MemoryView":1203
 *     else:
 *         for idx in range(ndim - 1, -1, -1):
 *             strides[idx] = stride             # <<<<<<<<<<<<<<
 *             stride = stride * shape[idx]
 * 
 */
      (__pyx_v_strides[__pyx_v_idx]) = __pyx_v_stride;

      /* "View.MemoryView":1204
 *         for idx in range(ndim - 1, -1, -1):
 *             strides[idx] = stride
 *             stride = stride * shape[idx]             # <<<<<<<<<<<<<<
 * 
 *     return stride
 */
      __pyx_v_stride = (__pyx_v_stride * (__pyx_v_shape[__pyx_v_idx]));
    }
  }
  __pyx_L3:;

  /* "View.MemoryView":1206
 *             stride = stride * shape[idx]
 * 
 *     return stride             # <<<<<<<<<<<<<<
 * 
 * @cname('__pyx_memoryview_copy_data_to_temp')
 */
  __pyx_r = __pyx_v_stride;
  goto __pyx_L0;

  /* "View.MemoryView":1188
 * 
 * @cname('__pyx_fill_contig_strides_array')
 * cdef Py_ssize_t fill_contig_strides_array(             # <<<<<<<<<<<<<<
 *                 Py_ssize_t *shape, Py_ssize_t *strides, Py_ssize_t stride,
 *                 int ndim, char order) nogil:
 */

  /* function exit code */
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}

/* "View.MemoryView":1209
 * 
 * @cname('__pyx_memoryview_copy_data_to_temp')
 * cdef void *copy_data_to_temp(__Pyx_memviewslice *src,             # <<<<<<<<<<<<<<
 *                              __Pyx_memviewslice *tmpslice,
 *                              char order,
 */

static void *__pyx_memoryview_copy_data_to_temp(__Pyx_memviewslice *__pyx_v_src, __Pyx_memviewslice *__pyx_v_tmpslice, char __pyx_v_order, int __pyx_v_ndim) {
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  size_t __pyx_v_size;
  void *__pyx_r;
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  int __pyx_t_3;
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  int __pyx_t_5;
  int __pyx_t_6;

  /* "View.MemoryView":1220
 *     cdef void *result
 * 
 *     cdef size_t itemsize = src.memview.view.itemsize             # <<<<<<<<<<<<<<
 *     cdef size_t size = slice_get_size(src, ndim)
 * 
 */
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  /* "View.MemoryView":1221
 * 
 *     cdef size_t itemsize = src.memview.view.itemsize
 *     cdef size_t size = slice_get_size(src, ndim)             # <<<<<<<<<<<<<<
 * 
 *     result = malloc(size)
 */
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  /* "View.MemoryView":1223
 *     cdef size_t size = slice_get_size(src, ndim)
 * 
 *     result = malloc(size)             # <<<<<<<<<<<<<<
 *     if not result:
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 */
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  /* "View.MemoryView":1224
 * 
 *     result = malloc(size)
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 */
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    /* "View.MemoryView":1225
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 * 
 * 
 */
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    /* "View.MemoryView":1224
 * 
 *     result = malloc(size)
 *     if not result:             # <<<<<<<<<<<<<<
 *         _err(MemoryError, NULL)
 * 
 */
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  /* "View.MemoryView":1228
 * 
 * 
 *     tmpslice.data = <char *> result             # <<<<<<<<<<<<<<
 *     tmpslice.memview = src.memview
 *     for i in range(ndim):
 */
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  /* "View.MemoryView":1229
 * 
 *     tmpslice.data = <char *> result
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 *     for i in range(ndim):
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 */
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  /* "View.MemoryView":1230
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 *     tmpslice.memview = src.memview
 *     for i in range(ndim):             # <<<<<<<<<<<<<<
 *         tmpslice.shape[i] = src.shape[i]
 *         tmpslice.suboffsets[i] = -1
 */
  __pyx_t_3 = __pyx_v_ndim;
  __pyx_t_5 = __pyx_t_3;
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    /* "View.MemoryView":1231
 *     tmpslice.memview = src.memview
 *     for i in range(ndim):
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 *         tmpslice.suboffsets[i] = -1
 * 
 */
    (__pyx_v_tmpslice->shape[__pyx_v_i]) = (__pyx_v_src->shape[__pyx_v_i]);

    /* "View.MemoryView":1232
 *     for i in range(ndim):
 *         tmpslice.shape[i] = src.shape[i]
 *         tmpslice.suboffsets[i] = -1             # <<<<<<<<<<<<<<
 * 
 *     fill_contig_strides_array(&tmpslice.shape[0], &tmpslice.strides[0], itemsize,
 */
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  /* "View.MemoryView":1234
 *         tmpslice.suboffsets[i] = -1
 * 
 *     fill_contig_strides_array(&tmpslice.shape[0], &tmpslice.strides[0], itemsize,             # <<<<<<<<<<<<<<
 *                               ndim, order)
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 */
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  /* "View.MemoryView":1238
 * 
 * 
 *     for i in range(ndim):             # <<<<<<<<<<<<<<
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 */
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  __pyx_t_5 = __pyx_t_3;
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    /* "View.MemoryView":1239
 * 
 *     for i in range(ndim):
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 *             tmpslice.strides[i] = 0
 * 
 */
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      /* "View.MemoryView":1240
 *     for i in range(ndim):
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 * 
 *     if slice_is_contig(src[0], order, ndim):
 */
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      /* "View.MemoryView":1239
 * 
 *     for i in range(ndim):
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 *             tmpslice.strides[i] = 0
 * 
 */
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 * 
 *     if slice_is_contig(src[0], order, ndim):             # <<<<<<<<<<<<<<
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    /* "View.MemoryView":1243
 * 
 *     if slice_is_contig(src[0], order, ndim):
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 */
    (void)(memcpy(__pyx_v_result, __pyx_v_src->data, __pyx_v_size));

    /* "View.MemoryView":1242
 *             tmpslice.strides[i] = 0
 * 
 *     if slice_is_contig(src[0], order, ndim):             # <<<<<<<<<<<<<<
 *         memcpy(result, src.data, size)
 *     else:
 */
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 *         memcpy(result, src.data, size)
 *     else:
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 * 
 *     return result
 */
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 *     return result             # <<<<<<<<<<<<<<
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 * 
 */
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  /* "View.MemoryView":1209
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/* "View.MemoryView":1252
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 *         tmpdata = copy_data_to_temp(&src, &tmp, order, ndim)             # <<<<<<<<<<<<<<
 *         src = tmp
 * 
 */
    __pyx_t_7 = __pyx_memoryview_copy_data_to_temp((&__pyx_v_src), (&__pyx_v_tmp), __pyx_v_order, __pyx_v_ndim); if (unlikely(__pyx_t_7 == ((void *)NULL))) __PYX_ERR(1, 1308, __pyx_L1_error)
    __pyx_v_tmpdata = __pyx_t_7;

    /* "View.MemoryView":1309
 * 
 *         tmpdata = copy_data_to_temp(&src, &tmp, order, ndim)
 *         src = tmp             # <<<<<<<<<<<<<<
 * 
 *     if not broadcasting:
 */
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    /* "View.MemoryView":1303
 *             _err_dim(ValueError, "Dimension %d is not direct", i)
 * 
 *     if slices_overlap(&src, &dst, ndim, itemsize):             # <<<<<<<<<<<<<<
 * 
 *         if not slice_is_contig(src, order, ndim):
 */
  }

  /* "View.MemoryView":1311
 *         src = tmp
 * 
 *     if not broadcasting:             # <<<<<<<<<<<<<<
 * 
 * 
 */
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    /* "View.MemoryView":1314
 * 
 * 
 *         if slice_is_contig(src, 'C', ndim):             # <<<<<<<<<<<<<<
 *             direct_copy = slice_is_contig(dst, 'C', ndim)
 *         elif slice_is_contig(src, 'F', ndim):
 */
    __pyx_t_2 = (__pyx_memviewslice_is_contig(__pyx_v_src, 'C', __pyx_v_ndim) != 0);
    if (__pyx_t_2) {

      /* "View.MemoryView":1315
 * 
 *         if slice_is_contig(src, 'C', ndim):
 *             direct_copy = slice_is_contig(dst, 'C', ndim)             # <<<<<<<<<<<<<<
 *         elif slice_is_contig(src, 'F', ndim):
 *             direct_copy = slice_is_contig(dst, 'F', ndim)
 */
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      /* "View.MemoryView":1314
 * 
 * 
 *         if slice_is_contig(src, 'C', ndim):             # <<<<<<<<<<<<<<
 *             direct_copy = slice_is_contig(dst, 'C', ndim)
 *         elif slice_is_contig(src, 'F', ndim):
 */
      goto __pyx_L12;
    }

    /* "View.MemoryView":1316
 *         if slice_is_contig(src, 'C', ndim):
 *             direct_copy = slice_is_contig(dst, 'C', ndim)
 *         elif slice_is_contig(src, 'F', ndim):             # <<<<<<<<<<<<<<
 *             direct_copy = slice_is_contig(dst, 'F', ndim)
 * 
 */
    __pyx_t_2 = (__pyx_memviewslice_is_contig(__pyx_v_src, 'F', __pyx_v_ndim) != 0);
    if (__pyx_t_2) {

      /* "View.MemoryView":1317
 *             direct_copy = slice_is_contig(dst, 'C', ndim)
 *         elif slice_is_contig(src, 'F', ndim):
 *             direct_copy = slice_is_contig(dst, 'F', ndim)             # <<<<<<<<<<<<<<
 * 
 *         if direct_copy:
 */
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      /* "View.MemoryView":1316
 *         if slice_is_contig(src, 'C', ndim):
 *             direct_copy = slice_is_contig(dst, 'C', ndim)
 *         elif slice_is_contig(src, 'F', ndim):             # <<<<<<<<<<<<<<
 *             direct_copy = slice_is_contig(dst, 'F', ndim)
 * 
 */
    }
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    /* "View.MemoryView":1319
 *             direct_copy = slice_is_contig(dst, 'F', ndim)
 * 
 *         if direct_copy:             # <<<<<<<<<<<<<<
 * 
 *             refcount_copying(&dst, dtype_is_object, ndim, False)
 */
    __pyx_t_2 = (__pyx_v_direct_copy != 0);
    if (__pyx_t_2) {

      /* "View.MemoryView":1321
 *         if direct_copy:
 * 
 *             refcount_copying(&dst, dtype_is_object, ndim, False)             # <<<<<<<<<<<<<<
 *             memcpy(dst.data, src.data, slice_get_size(&src, ndim))
 *             refcount_copying(&dst, dtype_is_object, ndim, True)
 */
      __pyx_memoryview_refcount_copying((&__pyx_v_dst), __pyx_v_dtype_is_object, __pyx_v_ndim, 0);

      /* "View.MemoryView":1322
 * 
 *             refcount_copying(&dst, dtype_is_object, ndim, False)
 *             memcpy(dst.data, src.data, slice_get_size(&src, ndim))             # <<<<<<<<<<<<<<
 *             refcount_copying(&dst, dtype_is_object, ndim, True)
 *             free(tmpdata)
 */
      (void)(memcpy(__pyx_v_dst.data, __pyx_v_src.data, __pyx_memoryview_slice_get_size((&__pyx_v_src), __pyx_v_ndim)));

      /* "View.MemoryView":1323
 *             refcount_copying(&dst, dtype_is_object, ndim, False)
 *             memcpy(dst.data, src.data, slice_get_size(&src, ndim))
 *             refcount_copying(&dst, dtype_is_object, ndim, True)             # <<<<<<<<<<<<<<
 *             free(tmpdata)
 *             return 0
 */
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      /* "View.MemoryView":1324
 *             memcpy(dst.data, src.data, slice_get_size(&src, ndim))
 *             refcount_copying(&dst, dtype_is_object, ndim, True)
 *             free(tmpdata)             # <<<<<<<<<<<<<<
 *             return 0
 * 
 */
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      /* "View.MemoryView":1325
 *             refcount_copying(&dst, dtype_is_object, ndim, True)
 *             free(tmpdata)
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 * 
 *     if order == 'F' == get_best_order(&dst, ndim):
 */
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 *             direct_copy = slice_is_contig(dst, 'F', ndim)
 * 
 *         if direct_copy:             # <<<<<<<<<<<<<<
 * 
 *             refcount_copying(&dst, dtype_is_object, ndim, False)
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    /* "View.MemoryView":1311
 *         src = tmp
 * 
 *     if not broadcasting:             # <<<<<<<<<<<<<<
 * 
 * 
 */
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 *             return 0
 * 
 *     if order == 'F' == get_best_order(&dst, ndim):             # <<<<<<<<<<<<<<
 * 
 * 
 */
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    /* "View.MemoryView":1330
 * 
 * 
 *         transpose_memslice(&src)             # <<<<<<<<<<<<<<
 *         transpose_memslice(&dst)
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 */
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 * 
 *         transpose_memslice(&src)
 *         transpose_memslice(&dst)             # <<<<<<<<<<<<<<
 * 
 *     refcount_copying(&dst, dtype_is_object, ndim, False)
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 * 
 *     if order == 'F' == get_best_order(&dst, ndim):             # <<<<<<<<<<<<<<
 * 
 * 
 */
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 *         transpose_memslice(&dst)
 * 
 *     refcount_copying(&dst, dtype_is_object, ndim, False)             # <<<<<<<<<<<<<<
 *     copy_strided_to_strided(&src, &dst, ndim, itemsize)
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 * 
 *     refcount_copying(&dst, dtype_is_object, ndim, False)
 *     copy_strided_to_strided(&src, &dst, ndim, itemsize)             # <<<<<<<<<<<<<<
 *     refcount_copying(&dst, dtype_is_object, ndim, True)
 * 
 */
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 *     refcount_copying(&dst, dtype_is_object, ndim, False)
 *     copy_strided_to_strided(&src, &dst, ndim, itemsize)
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 * 
 *     free(tmpdata)
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 *     refcount_copying(&dst, dtype_is_object, ndim, True)
 * 
 *     free(tmpdata)             # <<<<<<<<<<<<<<
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 * 
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 * 
 *     free(tmpdata)
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 * 
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 * 
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 * 
 *     for i in range(ndim - 1, -1, -1):             # <<<<<<<<<<<<<<
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 * 
 *     for i in range(ndim - 1, -1, -1):
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 *     for i in range(ndim - 1, -1, -1):
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 *         mslice.shape[i + offset] = mslice.shape[i]
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 *     for i in range(offset):
 */
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 * 
 *     for i in range(offset):             # <<<<<<<<<<<<<<
 *         mslice.shape[i] = 1
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 * 
 *     for i in range(offset):
 *         mslice.shape[i] = 1             # <<<<<<<<<<<<<<
 *         mslice.strides[i] = mslice.strides[0]
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 */
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    /* "View.MemoryView":1354
 *     for i in range(offset):
 *         mslice.shape[i] = 1
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 */
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 *         mslice.shape[i] = 1
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 *         mslice.suboffsets[i] = -1             # <<<<<<<<<<<<<<
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 * 
 */
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 * 
 * @cname('__pyx_memoryview_broadcast_leading')
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/* "View.MemoryView":1363
 * 
 * @cname('__pyx_memoryview_refcount_copying')
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 *                            int ndim, bint inc) nogil:
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 */

static void __pyx_memoryview_refcount_copying(__Pyx_memviewslice *__pyx_v_dst, int __pyx_v_dtype_is_object, int __pyx_v_ndim, int __pyx_v_inc) {
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 * 
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 * 
 *     if dtype_is_object:             # <<<<<<<<<<<<<<
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/* "View.MemoryView":1372
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 * @cname('__pyx_memoryview_refcount_objects_in_slice_with_gil')
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 * @cname('__pyx_memoryview_refcount_objects_in_slice')
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 * @cname('__pyx_memoryview_refcount_objects_in_slice_with_gil')
 * cdef void refcount_objects_in_slice_with_gil(char *data, Py_ssize_t *shape,             # <<<<<<<<<<<<<<
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static void __pyx_memoryview_refcount_objects_in_slice(char *__pyx_v_data, Py_ssize_t *__pyx_v_shape, Py_ssize_t *__pyx_v_strides, int __pyx_v_ndim, int __pyx_v_inc) {
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 *         data += strides[0]             # <<<<<<<<<<<<<<
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static struct __pyx_vtabstruct_13_rnaseq_utils_RNAseqMapping __pyx_vtable_13_rnaseq_utils_RNAseqMapping;

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static void __pyx_tp_dealloc_13_rnaseq_utils_RNAseqMapping(PyObject *o) {
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static int __pyx_tp_traverse_13_rnaseq_utils_RNAseqMapping(PyObject *o, visitproc v, void *a) {
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static int __pyx_tp_clear_13_rnaseq_utils_RNAseqMapping(PyObject *o) {
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static PyObject *__pyx_tp_richcompare_13_rnaseq_utils_RNAseqMapping(PyObject *o1, PyObject *o2, int op) {
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static PyObject *__pyx_getprop_13_rnaseq_utils_13RNAseqMapping_chrom(PyObject *o, CYTHON_UNUSED void *x) {
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static int __pyx_setprop_13_rnaseq_utils_13RNAseqMapping_chrom(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
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static PyObject *__pyx_getprop_13_rnaseq_utils_13RNAseqMapping_strand(PyObject *o, CYTHON_UNUSED void *x) {
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static int __pyx_setprop_13_rnaseq_utils_13RNAseqMapping_strand(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
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static PyObject *__pyx_getprop_13_rnaseq_utils_13RNAseqMapping_s_len(PyObject *o, CYTHON_UNUSED void *x) {
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static int __pyx_setprop_13_rnaseq_utils_13RNAseqMapping_s_len(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
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static PyObject *__pyx_getprop_13_rnaseq_utils_13RNAseqMapping_e_len(PyObject *o, CYTHON_UNUSED void *x) {
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static int __pyx_setprop_13_rnaseq_utils_13RNAseqMapping_e_len(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
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static PyObject *__pyx_getprop_13_rnaseq_utils_13RNAseqMapping_ranges(PyObject *o, CYTHON_UNUSED void *x) {
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static int __pyx_setprop_13_rnaseq_utils_13RNAseqMapping_ranges(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
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static PyObject *__pyx_getprop_13_rnaseq_utils_13RNAseqMapping_splice(PyObject *o, CYTHON_UNUSED void *x) {
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}

static int __pyx_setprop_13_rnaseq_utils_13RNAseqMapping_splice(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
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static PyObject *__pyx_getprop_13_rnaseq_utils_13RNAseqMapping_s_tag(PyObject *o, CYTHON_UNUSED void *x) {
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static int __pyx_setprop_13_rnaseq_utils_13RNAseqMapping_s_tag(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
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static PyObject *__pyx_getprop_13_rnaseq_utils_13RNAseqMapping_e_tag(PyObject *o, CYTHON_UNUSED void *x) {
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static int __pyx_setprop_13_rnaseq_utils_13RNAseqMapping_e_tag(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
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static PyObject *__pyx_getprop_13_rnaseq_utils_13RNAseqMapping_capped(PyObject *o, CYTHON_UNUSED void *x) {
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static int __pyx_setprop_13_rnaseq_utils_13RNAseqMapping_capped(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
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static PyObject *__pyx_getprop_13_rnaseq_utils_13RNAseqMapping_complete(PyObject *o, CYTHON_UNUSED void *x) {
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static int __pyx_setprop_13_rnaseq_utils_13RNAseqMapping_complete(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
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static PyObject *__pyx_getprop_13_rnaseq_utils_13RNAseqMapping_is_reference(PyObject *o, CYTHON_UNUSED void *x) {
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static int __pyx_setprop_13_rnaseq_utils_13RNAseqMapping_is_reference(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
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static PyObject *__pyx_getprop_13_rnaseq_utils_13RNAseqMapping_attributes(PyObject *o, CYTHON_UNUSED void *x) {
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static int __pyx_setprop_13_rnaseq_utils_13RNAseqMapping_attributes(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
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static PyObject *__pyx_getprop_13_rnaseq_utils_13RNAseqMapping_span(PyObject *o, CYTHON_UNUSED void *x) {
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static int __pyx_setprop_13_rnaseq_utils_13RNAseqMapping_span(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
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static PyObject *__pyx_getprop_13_rnaseq_utils_13RNAseqMapping_weight(PyObject *o, CYTHON_UNUSED void *x) {
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static int __pyx_setprop_13_rnaseq_utils_13RNAseqMapping_weight(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
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static PyObject *__pyx_getprop_13_rnaseq_utils_13RNAseqMapping_coverage(PyObject *o, CYTHON_UNUSED void *x) {
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static int __pyx_setprop_13_rnaseq_utils_13RNAseqMapping_coverage(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
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  {"diff", (PyCFunction)__pyx_pw_13_rnaseq_utils_13RNAseqMapping_29diff, METH_O, __pyx_doc_13_rnaseq_utils_13RNAseqMapping_28diff},
  {"overlaps", (PyCFunction)__pyx_pw_13_rnaseq_utils_13RNAseqMapping_31overlaps, METH_O, __pyx_doc_13_rnaseq_utils_13RNAseqMapping_30overlaps},
  {"overlap_range", (PyCFunction)__pyx_pw_13_rnaseq_utils_13RNAseqMapping_33overlap_range, METH_O, __pyx_doc_13_rnaseq_utils_13RNAseqMapping_32overlap_range},
  {"ends_clash", (PyCFunction)__pyx_pw_13_rnaseq_utils_13RNAseqMapping_35ends_clash, METH_O, __pyx_doc_13_rnaseq_utils_13RNAseqMapping_34ends_clash},
  {"splice_match", (PyCFunction)(void*)(PyCFunctionWithKeywords)__pyx_pw_13_rnaseq_utils_13RNAseqMapping_37splice_match, METH_VARARGS|METH_KEYWORDS, __pyx_doc_13_rnaseq_utils_13RNAseqMapping_36splice_match},
  {"antisense_match", (PyCFunction)(void*)(PyCFunctionWithKeywords)__pyx_pw_13_rnaseq_utils_13RNAseqMapping_39antisense_match, METH_VARARGS|METH_KEYWORDS, __pyx_doc_13_rnaseq_utils_13RNAseqMapping_38antisense_match},
  {"sense_match", (PyCFunction)(void*)(PyCFunctionWithKeywords)__pyx_pw_13_rnaseq_utils_13RNAseqMapping_41sense_match, METH_VARARGS|METH_KEYWORDS, __pyx_doc_13_rnaseq_utils_13RNAseqMapping_40sense_match},
  {"is_compatible", (PyCFunction)(void*)(PyCFunctionWithKeywords)__pyx_pw_13_rnaseq_utils_13RNAseqMapping_43is_compatible, METH_VARARGS|METH_KEYWORDS, __pyx_doc_13_rnaseq_utils_13RNAseqMapping_42is_compatible},
  {"is_identical", (PyCFunction)__pyx_pw_13_rnaseq_utils_13RNAseqMapping_45is_identical, METH_O, __pyx_doc_13_rnaseq_utils_13RNAseqMapping_44is_identical},
  {"merge", (PyCFunction)__pyx_pw_13_rnaseq_utils_13RNAseqMapping_47merge, METH_O, __pyx_doc_13_rnaseq_utils_13RNAseqMapping_46merge},
  {"get_node_labels", (PyCFunction)(void*)(PyCFunctionWithKeywords)__pyx_pw_13_rnaseq_utils_13RNAseqMapping_49get_node_labels, METH_VARARGS|METH_KEYWORDS, __pyx_doc_13_rnaseq_utils_13RNAseqMapping_48get_node_labels},
  {"write_as_elr", (PyCFunction)(void*)(PyCFunctionWithKeywords)__pyx_pw_13_rnaseq_utils_13RNAseqMapping_51write_as_elr, METH_VARARGS|METH_KEYWORDS, __pyx_doc_13_rnaseq_utils_13RNAseqMapping_50write_as_elr},
  {"write_as_bed", (PyCFunction)(void*)(PyCFunctionWithKeywords)__pyx_pw_13_rnaseq_utils_13RNAseqMapping_53write_as_bed, METH_VARARGS|METH_KEYWORDS, __pyx_doc_13_rnaseq_utils_13RNAseqMapping_52write_as_bed},
  {"write_as_gtf", (PyCFunction)(void*)(PyCFunctionWithKeywords)__pyx_pw_13_rnaseq_utils_13RNAseqMapping_55write_as_gtf, METH_VARARGS|METH_KEYWORDS, __pyx_doc_13_rnaseq_utils_13RNAseqMapping_54write_as_gtf},
  {"print_attributes", (PyCFunction)(void*)(PyCFunctionWithKeywords)__pyx_pw_13_rnaseq_utils_13RNAseqMapping_57print_attributes, METH_VARARGS|METH_KEYWORDS, __pyx_doc_13_rnaseq_utils_13RNAseqMapping_56print_attributes},
  {"write_as_json", (PyCFunction)(void*)(PyCFunctionWithKeywords)__pyx_pw_13_rnaseq_utils_13RNAseqMapping_59write_as_json, METH_VARARGS|METH_KEYWORDS, __pyx_doc_13_rnaseq_utils_13RNAseqMapping_58write_as_json},
  {"__reduce_cython__", (PyCFunction)__pyx_pw_13_rnaseq_utils_13RNAseqMapping_61__reduce_cython__, METH_NOARGS, 0},
  {"__setstate_cython__", (PyCFunction)__pyx_pw_13_rnaseq_utils_13RNAseqMapping_63__setstate_cython__, METH_O, 0},
  {0, 0, 0, 0}
};

static struct PyGetSetDef __pyx_getsets_13_rnaseq_utils_RNAseqMapping[] = {
  {(char *)"chrom", __pyx_getprop_13_rnaseq_utils_13RNAseqMapping_chrom, __pyx_setprop_13_rnaseq_utils_13RNAseqMapping_chrom, (char *)0, 0},
  {(char *)"source", __pyx_getprop_13_rnaseq_utils_13RNAseqMapping_source, __pyx_setprop_13_rnaseq_utils_13RNAseqMapping_source, (char *)0, 0},
  {(char *)"strand", __pyx_getprop_13_rnaseq_utils_13RNAseqMapping_strand, __pyx_setprop_13_rnaseq_utils_13RNAseqMapping_strand, (char *)0, 0},
  {(char *)"s_len", __pyx_getprop_13_rnaseq_utils_13RNAseqMapping_s_len, __pyx_setprop_13_rnaseq_utils_13RNAseqMapping_s_len, (char *)0, 0},
  {(char *)"e_len", __pyx_getprop_13_rnaseq_utils_13RNAseqMapping_e_len, __pyx_setprop_13_rnaseq_utils_13RNAseqMapping_e_len, (char *)0, 0},
  {(char *)"ranges", __pyx_getprop_13_rnaseq_utils_13RNAseqMapping_ranges, __pyx_setprop_13_rnaseq_utils_13RNAseqMapping_ranges, (char *)0, 0},
  {(char *)"splice", __pyx_getprop_13_rnaseq_utils_13RNAseqMapping_splice, __pyx_setprop_13_rnaseq_utils_13RNAseqMapping_splice, (char *)0, 0},
  {(char *)"s_tag", __pyx_getprop_13_rnaseq_utils_13RNAseqMapping_s_tag, __pyx_setprop_13_rnaseq_utils_13RNAseqMapping_s_tag, (char *)0, 0},
  {(char *)"e_tag", __pyx_getprop_13_rnaseq_utils_13RNAseqMapping_e_tag, __pyx_setprop_13_rnaseq_utils_13RNAseqMapping_e_tag, (char *)0, 0},
  {(char *)"capped", __pyx_getprop_13_rnaseq_utils_13RNAseqMapping_capped, __pyx_setprop_13_rnaseq_utils_13RNAseqMapping_capped, (char *)0, 0},
  {(char *)"complete", __pyx_getprop_13_rnaseq_utils_13RNAseqMapping_complete, __pyx_setprop_13_rnaseq_utils_13RNAseqMapping_complete, (char *)0, 0},
  {(char *)"is_reference", __pyx_getprop_13_rnaseq_utils_13RNAseqMapping_is_reference, __pyx_setprop_13_rnaseq_utils_13RNAseqMapping_is_reference, (char *)0, 0},
  {(char *)"attributes", __pyx_getprop_13_rnaseq_utils_13RNAseqMapping_attributes, __pyx_setprop_13_rnaseq_utils_13RNAseqMapping_attributes, (char *)0, 0},
  {(char *)"span", __pyx_getprop_13_rnaseq_utils_13RNAseqMapping_span, __pyx_setprop_13_rnaseq_utils_13RNAseqMapping_span, (char *)0, 0},
  {(char *)"weight", __pyx_getprop_13_rnaseq_utils_13RNAseqMapping_weight, __pyx_setprop_13_rnaseq_utils_13RNAseqMapping_weight, (char *)0, 0},
  {(char *)"coverage", __pyx_getprop_13_rnaseq_utils_13RNAseqMapping_coverage, __pyx_setprop_13_rnaseq_utils_13RNAseqMapping_coverage, (char *)0, 0},
  {0, 0, 0, 0, 0}
};

static PySequenceMethods __pyx_tp_as_sequence_RNAseqMapping = {
  __pyx_pw_13_rnaseq_utils_13RNAseqMapping_17__len__, /*sq_length*/
  0, /*sq_concat*/
  0, /*sq_repeat*/
  0, /*sq_item*/
  0, /*sq_slice*/
  0, /*sq_ass_item*/
  0, /*sq_ass_slice*/
  0, /*sq_contains*/
  0, /*sq_inplace_concat*/
  0, /*sq_inplace_repeat*/
};

static PyMappingMethods __pyx_tp_as_mapping_RNAseqMapping = {
  __pyx_pw_13_rnaseq_utils_13RNAseqMapping_17__len__, /*mp_length*/
  0, /*mp_subscript*/
  0, /*mp_ass_subscript*/
};

static PyTypeObject __pyx_type_13_rnaseq_utils_RNAseqMapping = {
  PyVarObject_HEAD_INIT(0, 0)
  "_rnaseq_utils.RNAseqMapping", /*tp_name*/
  sizeof(struct __pyx_obj_13_rnaseq_utils_RNAseqMapping), /*tp_basicsize*/
  0, /*tp_itemsize*/
  __pyx_tp_dealloc_13_rnaseq_utils_RNAseqMapping, /*tp_dealloc*/
  0, /*tp_print*/
  0, /*tp_getattr*/
  0, /*tp_setattr*/
  #if PY_MAJOR_VERSION < 3
  0, /*tp_compare*/
  #endif
  #if PY_MAJOR_VERSION >= 3
  0, /*tp_as_async*/
  #endif
  __pyx_pw_13_rnaseq_utils_13RNAseqMapping_15__repr__, /*tp_repr*/
  0, /*tp_as_number*/
  &__pyx_tp_as_sequence_RNAseqMapping, /*tp_as_sequence*/
  &__pyx_tp_as_mapping_RNAseqMapping, /*tp_as_mapping*/
  0, /*tp_hash*/
  0, /*tp_call*/
  0, /*tp_str*/
  0, /*tp_getattro*/
  0, /*tp_setattro*/
  0, /*tp_as_buffer*/
  Py_TPFLAGS_DEFAULT|Py_TPFLAGS_HAVE_VERSION_TAG|Py_TPFLAGS_CHECKTYPES|Py_TPFLAGS_HAVE_NEWBUFFER|Py_TPFLAGS_BASETYPE|Py_TPFLAGS_HAVE_GC, /*tp_flags*/
  0, /*tp_doc*/
  __pyx_tp_traverse_13_rnaseq_utils_RNAseqMapping, /*tp_traverse*/
  __pyx_tp_clear_13_rnaseq_utils_RNAseqMapping, /*tp_clear*/
  __pyx_tp_richcompare_13_rnaseq_utils_RNAseqMapping, /*tp_richcompare*/
  0, /*tp_weaklistoffset*/
  0, /*tp_iter*/
  0, /*tp_iternext*/
  __pyx_methods_13_rnaseq_utils_RNAseqMapping, /*tp_methods*/
  0, /*tp_members*/
  __pyx_getsets_13_rnaseq_utils_RNAseqMapping, /*tp_getset*/
  0, /*tp_base*/
  0, /*tp_dict*/
  0, /*tp_descr_get*/
  0, /*tp_descr_set*/
  0, /*tp_dictoffset*/
  __pyx_pw_13_rnaseq_utils_13RNAseqMapping_1__init__, /*tp_init*/
  0, /*tp_alloc*/
  __pyx_tp_new_13_rnaseq_utils_RNAseqMapping, /*tp_new*/
  0, /*tp_free*/
  0, /*tp_is_gc*/
  0, /*tp_bases*/
  0, /*tp_mro*/
  0, /*tp_cache*/
  0, /*tp_subclasses*/
  0, /*tp_weaklist*/
  0, /*tp_del*/
  0, /*tp_version_tag*/
  #if PY_VERSION_HEX >= 0x030400a1
  0, /*tp_finalize*/
  #endif
  #if PY_VERSION_HEX >= 0x030800b1
  0, /*tp_vectorcall*/
  #endif
};
static struct __pyx_vtabstruct_13_rnaseq_utils_RNAseqDataset __pyx_vtable_13_rnaseq_utils_RNAseqDataset;

static PyObject *__pyx_tp_new_13_rnaseq_utils_RNAseqDataset(PyTypeObject *t, CYTHON_UNUSED PyObject *a, CYTHON_UNUSED PyObject *k) {
  struct __pyx_obj_13_rnaseq_utils_RNAseqDataset *p;
  PyObject *o;
  if (likely((t->tp_flags & Py_TPFLAGS_IS_ABSTRACT) == 0)) {
    o = (*t->tp_alloc)(t, 0);
  } else {
    o = (PyObject *) PyBaseObject_Type.tp_new(t, __pyx_empty_tuple, 0);
  }
  if (unlikely(!o)) return 0;
  p = ((struct __pyx_obj_13_rnaseq_utils_RNAseqDataset *)o);
  p->__pyx_vtab = __pyx_vtabptr_13_rnaseq_utils_RNAseqDataset;
  p->read_list = ((PyObject*)Py_None); Py_INCREF(Py_None);
  p->chrom_array = ((PyObject*)Py_None); Py_INCREF(Py_None);
  p->source_array = ((PyObject*)Py_None); Py_INCREF(Py_None);
  p->chrom_lengths = ((PyObject*)Py_None); Py_INCREF(Py_None);
  p->chrom_dict = ((PyObject*)Py_None); Py_INCREF(Py_None);
  p->source_dict = ((PyObject*)Py_None); Py_INCREF(Py_None);
  p->config = ((PyObject*)Py_None); Py_INCREF(Py_None);
  p->genome = ((PyObject*)Py_None); Py_INCREF(Py_None);
  p->label_tally = ((PyObject*)Py_None); Py_INCREF(Py_None);
  p->start_seq = ((PyObject*)Py_None); Py_INCREF(Py_None);
  p->end_seq = ((PyObject*)Py_None); Py_INCREF(Py_None);
  p->start_array = ((arrayobject *)Py_None); Py_INCREF(Py_None);
  p->end_array = ((arrayobject *)Py_None); Py_INCREF(Py_None);
  return o;
}

static void __pyx_tp_dealloc_13_rnaseq_utils_RNAseqDataset(PyObject *o) {
  struct __pyx_obj_13_rnaseq_utils_RNAseqDataset *p = (struct __pyx_obj_13_rnaseq_utils_RNAseqDataset *)o;
  #if CYTHON_USE_TP_FINALIZE
  if (unlikely(PyType_HasFeature(Py_TYPE(o), Py_TPFLAGS_HAVE_FINALIZE) && Py_TYPE(o)->tp_finalize) && !_PyGC_FINALIZED(o)) {
    if (PyObject_CallFinalizerFromDealloc(o)) return;
  }
  #endif
  PyObject_GC_UnTrack(o);
  Py_CLEAR(p->read_list);
  Py_CLEAR(p->chrom_array);
  Py_CLEAR(p->source_array);
  Py_CLEAR(p->chrom_lengths);
  Py_CLEAR(p->chrom_dict);
  Py_CLEAR(p->source_dict);
  Py_CLEAR(p->config);
  Py_CLEAR(p->genome);
  Py_CLEAR(p->label_tally);
  Py_CLEAR(p->start_seq);
  Py_CLEAR(p->end_seq);
  Py_CLEAR(p->start_array);
  Py_CLEAR(p->end_array);
  (*Py_TYPE(o)->tp_free)(o);
}

static int __pyx_tp_traverse_13_rnaseq_utils_RNAseqDataset(PyObject *o, visitproc v, void *a) {
  int e;
  struct __pyx_obj_13_rnaseq_utils_RNAseqDataset *p = (struct __pyx_obj_13_rnaseq_utils_RNAseqDataset *)o;
  if (p->read_list) {
    e = (*v)(p->read_list, a); if (e) return e;
  }
  if (p->chrom_array) {
    e = (*v)(p->chrom_array, a); if (e) return e;
  }
  if (p->source_array) {
    e = (*v)(p->source_array, a); if (e) return e;
  }
  if (p->chrom_lengths) {
    e = (*v)(p->chrom_lengths, a); if (e) return e;
  }
  if (p->chrom_dict) {
    e = (*v)(p->chrom_dict, a); if (e) return e;
  }
  if (p->source_dict) {
    e = (*v)(p->source_dict, a); if (e) return e;
  }
  if (p->config) {
    e = (*v)(p->config, a); if (e) return e;
  }
  if (p->genome) {
    e = (*v)(p->genome, a); if (e) return e;
  }
  if (p->label_tally) {
    e = (*v)(p->label_tally, a); if (e) return e;
  }
  if (p->start_array) {
    e = (*v)(((PyObject *)p->start_array), a); if (e) return e;
  }
  if (p->end_array) {
    e = (*v)(((PyObject *)p->end_array), a); if (e) return e;
  }
  return 0;
}

static int __pyx_tp_clear_13_rnaseq_utils_RNAseqDataset(PyObject *o) {
  PyObject* tmp;
  struct __pyx_obj_13_rnaseq_utils_RNAseqDataset *p = (struct __pyx_obj_13_rnaseq_utils_RNAseqDataset *)o;
  tmp = ((PyObject*)p->read_list);
  p->read_list = ((PyObject*)Py_None); Py_INCREF(Py_None);
  Py_XDECREF(tmp);
  tmp = ((PyObject*)p->chrom_array);
  p->chrom_array = ((PyObject*)Py_None); Py_INCREF(Py_None);
  Py_XDECREF(tmp);
  tmp = ((PyObject*)p->source_array);
  p->source_array = ((PyObject*)Py_None); Py_INCREF(Py_None);
  Py_XDECREF(tmp);
  tmp = ((PyObject*)p->chrom_lengths);
  p->chrom_lengths = ((PyObject*)Py_None); Py_INCREF(Py_None);
  Py_XDECREF(tmp);
  tmp = ((PyObject*)p->chrom_dict);
  p->chrom_dict = ((PyObject*)Py_None); Py_INCREF(Py_None);
  Py_XDECREF(tmp);
  tmp = ((PyObject*)p->source_dict);
  p->source_dict = ((PyObject*)Py_None); Py_INCREF(Py_None);
  Py_XDECREF(tmp);
  tmp = ((PyObject*)p->config);
  p->config = ((PyObject*)Py_None); Py_INCREF(Py_None);
  Py_XDECREF(tmp);
  tmp = ((PyObject*)p->genome);
  p->genome = ((PyObject*)Py_None); Py_INCREF(Py_None);
  Py_XDECREF(tmp);
  tmp = ((PyObject*)p->label_tally);
  p->label_tally = ((PyObject*)Py_None); Py_INCREF(Py_None);
  Py_XDECREF(tmp);
  tmp = ((PyObject*)p->start_array);
  p->start_array = ((arrayobject *)Py_None); Py_INCREF(Py_None);
  Py_XDECREF(tmp);
  tmp = ((PyObject*)p->end_array);
  p->end_array = ((arrayobject *)Py_None); Py_INCREF(Py_None);
  Py_XDECREF(tmp);
  return 0;
}

static PyObject *__pyx_getprop_13_rnaseq_utils_13RNAseqDataset_read_list(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_13RNAseqDataset_9read_list_1__get__(o);
}

static int __pyx_setprop_13_rnaseq_utils_13RNAseqDataset_read_list(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
  if (v) {
    return __pyx_pw_13_rnaseq_utils_13RNAseqDataset_9read_list_3__set__(o, v);
  }
  else {
    return __pyx_pw_13_rnaseq_utils_13RNAseqDataset_9read_list_5__del__(o);
  }
}

static PyObject *__pyx_getprop_13_rnaseq_utils_13RNAseqDataset_chrom_array(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_13RNAseqDataset_11chrom_array_1__get__(o);
}

static int __pyx_setprop_13_rnaseq_utils_13RNAseqDataset_chrom_array(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
  if (v) {
    return __pyx_pw_13_rnaseq_utils_13RNAseqDataset_11chrom_array_3__set__(o, v);
  }
  else {
    return __pyx_pw_13_rnaseq_utils_13RNAseqDataset_11chrom_array_5__del__(o);
  }
}

static PyObject *__pyx_getprop_13_rnaseq_utils_13RNAseqDataset_source_array(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_13RNAseqDataset_12source_array_1__get__(o);
}

static int __pyx_setprop_13_rnaseq_utils_13RNAseqDataset_source_array(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
  if (v) {
    return __pyx_pw_13_rnaseq_utils_13RNAseqDataset_12source_array_3__set__(o, v);
  }
  else {
    return __pyx_pw_13_rnaseq_utils_13RNAseqDataset_12source_array_5__del__(o);
  }
}

static PyObject *__pyx_getprop_13_rnaseq_utils_13RNAseqDataset_chrom_lengths(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_13RNAseqDataset_13chrom_lengths_1__get__(o);
}

static int __pyx_setprop_13_rnaseq_utils_13RNAseqDataset_chrom_lengths(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
  if (v) {
    return __pyx_pw_13_rnaseq_utils_13RNAseqDataset_13chrom_lengths_3__set__(o, v);
  }
  else {
    return __pyx_pw_13_rnaseq_utils_13RNAseqDataset_13chrom_lengths_5__del__(o);
  }
}

static PyObject *__pyx_getprop_13_rnaseq_utils_13RNAseqDataset_chrom_index(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_13RNAseqDataset_11chrom_index_1__get__(o);
}

static int __pyx_setprop_13_rnaseq_utils_13RNAseqDataset_chrom_index(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
  if (v) {
    return __pyx_pw_13_rnaseq_utils_13RNAseqDataset_11chrom_index_3__set__(o, v);
  }
  else {
    PyErr_SetString(PyExc_NotImplementedError, "__del__");
    return -1;
  }
}

static PyObject *__pyx_getprop_13_rnaseq_utils_13RNAseqDataset_source_index(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_13RNAseqDataset_12source_index_1__get__(o);
}

static int __pyx_setprop_13_rnaseq_utils_13RNAseqDataset_source_index(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
  if (v) {
    return __pyx_pw_13_rnaseq_utils_13RNAseqDataset_12source_index_3__set__(o, v);
  }
  else {
    PyErr_SetString(PyExc_NotImplementedError, "__del__");
    return -1;
  }
}

static PyObject *__pyx_getprop_13_rnaseq_utils_13RNAseqDataset_chrom_dict(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_13RNAseqDataset_10chrom_dict_1__get__(o);
}

static int __pyx_setprop_13_rnaseq_utils_13RNAseqDataset_chrom_dict(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
  if (v) {
    return __pyx_pw_13_rnaseq_utils_13RNAseqDataset_10chrom_dict_3__set__(o, v);
  }
  else {
    return __pyx_pw_13_rnaseq_utils_13RNAseqDataset_10chrom_dict_5__del__(o);
  }
}

static PyObject *__pyx_getprop_13_rnaseq_utils_13RNAseqDataset_source_dict(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_13RNAseqDataset_11source_dict_1__get__(o);
}

static int __pyx_setprop_13_rnaseq_utils_13RNAseqDataset_source_dict(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
  if (v) {
    return __pyx_pw_13_rnaseq_utils_13RNAseqDataset_11source_dict_3__set__(o, v);
  }
  else {
    return __pyx_pw_13_rnaseq_utils_13RNAseqDataset_11source_dict_5__del__(o);
  }
}

static PyObject *__pyx_getprop_13_rnaseq_utils_13RNAseqDataset_config(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_13RNAseqDataset_6config_1__get__(o);
}

static PyObject *__pyx_getprop_13_rnaseq_utils_13RNAseqDataset_genome(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_13RNAseqDataset_6genome_1__get__(o);
}

static PyObject *__pyx_getprop_13_rnaseq_utils_13RNAseqDataset_label_tally(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_13RNAseqDataset_11label_tally_1__get__(o);
}

static PyObject *__pyx_getprop_13_rnaseq_utils_13RNAseqDataset_s_tag(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_13RNAseqDataset_5s_tag_1__get__(o);
}

static PyObject *__pyx_getprop_13_rnaseq_utils_13RNAseqDataset_e_tag(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_13RNAseqDataset_5e_tag_1__get__(o);
}

static PyObject *__pyx_getprop_13_rnaseq_utils_13RNAseqDataset_capped(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_13RNAseqDataset_6capped_1__get__(o);
}

static PyObject *__pyx_getprop_13_rnaseq_utils_13RNAseqDataset_stranded(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_13RNAseqDataset_8stranded_1__get__(o);
}

static PyObject *__pyx_getprop_13_rnaseq_utils_13RNAseqDataset_ignore_ends(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_13RNAseqDataset_11ignore_ends_1__get__(o);
}

static PyObject *__pyx_getprop_13_rnaseq_utils_13RNAseqDataset_start_seq(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_13RNAseqDataset_9start_seq_1__get__(o);
}

static PyObject *__pyx_getprop_13_rnaseq_utils_13RNAseqDataset_end_seq(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_13RNAseqDataset_7end_seq_1__get__(o);
}

static PyObject *__pyx_getprop_13_rnaseq_utils_13RNAseqDataset_minlen(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_13RNAseqDataset_6minlen_1__get__(o);
}

static PyObject *__pyx_getprop_13_rnaseq_utils_13RNAseqDataset_minlen_strict(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_13RNAseqDataset_13minlen_strict_1__get__(o);
}

static PyObject *__pyx_getprop_13_rnaseq_utils_13RNAseqDataset_minlen_loose(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_13RNAseqDataset_12minlen_loose_1__get__(o);
}

static PyObject *__pyx_getprop_13_rnaseq_utils_13RNAseqDataset_mismatch_rate(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_13RNAseqDataset_13mismatch_rate_1__get__(o);
}

static PyObject *__pyx_getprop_13_rnaseq_utils_13RNAseqDataset_start_array(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_13RNAseqDataset_11start_array_1__get__(o);
}

static PyObject *__pyx_getprop_13_rnaseq_utils_13RNAseqDataset_end_array(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_13RNAseqDataset_9end_array_1__get__(o);
}

static PyMethodDef __pyx_methods_13_rnaseq_utils_RNAseqDataset[] = {
  {"add_source", (PyCFunction)__pyx_pw_13_rnaseq_utils_13RNAseqDataset_3add_source, METH_O, 0},
  {"add_chrom", (PyCFunction)__pyx_pw_13_rnaseq_utils_13RNAseqDataset_5add_chrom, METH_O, 0},
  {"add_read_from_BED", (PyCFunction)(void*)(PyCFunctionWithKeywords)__pyx_pw_13_rnaseq_utils_13RNAseqDataset_7add_read_from_BED, METH_VARARGS|METH_KEYWORDS, 0},
  {"add_read", (PyCFunction)__pyx_pw_13_rnaseq_utils_13RNAseqDataset_9add_read, METH_O, 0},
  {"add_read_from_ELR", (PyCFunction)__pyx_pw_13_rnaseq_utils_13RNAseqDataset_11add_read_from_ELR, METH_O, 0},
  {"add_read_from_BAM", (PyCFunction)(void*)(PyCFunctionWithKeywords)__pyx_pw_13_rnaseq_utils_13RNAseqDataset_13add_read_from_BAM, METH_VARARGS|METH_KEYWORDS, 0},
  {"pop_read", (PyCFunction)(void*)(PyCFunctionWithKeywords)__pyx_pw_13_rnaseq_utils_13RNAseqDataset_15pop_read, METH_VARARGS|METH_KEYWORDS, __pyx_doc_13_rnaseq_utils_13RNAseqDataset_14pop_read},
  {"dump_header", (PyCFunction)__pyx_pw_13_rnaseq_utils_13RNAseqDataset_17dump_header, METH_NOARGS, __pyx_doc_13_rnaseq_utils_13RNAseqDataset_16dump_header},
  {"__reduce_cython__", (PyCFunction)__pyx_pw_13_rnaseq_utils_13RNAseqDataset_19__reduce_cython__, METH_NOARGS, 0},
  {"__setstate_cython__", (PyCFunction)__pyx_pw_13_rnaseq_utils_13RNAseqDataset_21__setstate_cython__, METH_O, 0},
  {0, 0, 0, 0}
};

static struct PyGetSetDef __pyx_getsets_13_rnaseq_utils_RNAseqDataset[] = {
  {(char *)"read_list", __pyx_getprop_13_rnaseq_utils_13RNAseqDataset_read_list, __pyx_setprop_13_rnaseq_utils_13RNAseqDataset_read_list, (char *)0, 0},
  {(char *)"chrom_array", __pyx_getprop_13_rnaseq_utils_13RNAseqDataset_chrom_array, __pyx_setprop_13_rnaseq_utils_13RNAseqDataset_chrom_array, (char *)0, 0},
  {(char *)"source_array", __pyx_getprop_13_rnaseq_utils_13RNAseqDataset_source_array, __pyx_setprop_13_rnaseq_utils_13RNAseqDataset_source_array, (char *)0, 0},
  {(char *)"chrom_lengths", __pyx_getprop_13_rnaseq_utils_13RNAseqDataset_chrom_lengths, __pyx_setprop_13_rnaseq_utils_13RNAseqDataset_chrom_lengths, (char *)0, 0},
  {(char *)"chrom_index", __pyx_getprop_13_rnaseq_utils_13RNAseqDataset_chrom_index, __pyx_setprop_13_rnaseq_utils_13RNAseqDataset_chrom_index, (char *)0, 0},
  {(char *)"source_index", __pyx_getprop_13_rnaseq_utils_13RNAseqDataset_source_index, __pyx_setprop_13_rnaseq_utils_13RNAseqDataset_source_index, (char *)0, 0},
  {(char *)"chrom_dict", __pyx_getprop_13_rnaseq_utils_13RNAseqDataset_chrom_dict, __pyx_setprop_13_rnaseq_utils_13RNAseqDataset_chrom_dict, (char *)0, 0},
  {(char *)"source_dict", __pyx_getprop_13_rnaseq_utils_13RNAseqDataset_source_dict, __pyx_setprop_13_rnaseq_utils_13RNAseqDataset_source_dict, (char *)0, 0},
  {(char *)"config", __pyx_getprop_13_rnaseq_utils_13RNAseqDataset_config, 0, (char *)0, 0},
  {(char *)"genome", __pyx_getprop_13_rnaseq_utils_13RNAseqDataset_genome, 0, (char *)0, 0},
  {(char *)"label_tally", __pyx_getprop_13_rnaseq_utils_13RNAseqDataset_label_tally, 0, (char *)0, 0},
  {(char *)"s_tag", __pyx_getprop_13_rnaseq_utils_13RNAseqDataset_s_tag, 0, (char *)0, 0},
  {(char *)"e_tag", __pyx_getprop_13_rnaseq_utils_13RNAseqDataset_e_tag, 0, (char *)0, 0},
  {(char *)"capped", __pyx_getprop_13_rnaseq_utils_13RNAseqDataset_capped, 0, (char *)0, 0},
  {(char *)"stranded", __pyx_getprop_13_rnaseq_utils_13RNAseqDataset_stranded, 0, (char *)0, 0},
  {(char *)"ignore_ends", __pyx_getprop_13_rnaseq_utils_13RNAseqDataset_ignore_ends, 0, (char *)0, 0},
  {(char *)"start_seq", __pyx_getprop_13_rnaseq_utils_13RNAseqDataset_start_seq, 0, (char *)0, 0},
  {(char *)"end_seq", __pyx_getprop_13_rnaseq_utils_13RNAseqDataset_end_seq, 0, (char *)0, 0},
  {(char *)"minlen", __pyx_getprop_13_rnaseq_utils_13RNAseqDataset_minlen, 0, (char *)0, 0},
  {(char *)"minlen_strict", __pyx_getprop_13_rnaseq_utils_13RNAseqDataset_minlen_strict, 0, (char *)0, 0},
  {(char *)"minlen_loose", __pyx_getprop_13_rnaseq_utils_13RNAseqDataset_minlen_loose, 0, (char *)0, 0},
  {(char *)"mismatch_rate", __pyx_getprop_13_rnaseq_utils_13RNAseqDataset_mismatch_rate, 0, (char *)0, 0},
  {(char *)"start_array", __pyx_getprop_13_rnaseq_utils_13RNAseqDataset_start_array, 0, (char *)0, 0},
  {(char *)"end_array", __pyx_getprop_13_rnaseq_utils_13RNAseqDataset_end_array, 0, (char *)0, 0},
  {0, 0, 0, 0, 0}
};

static PyTypeObject __pyx_type_13_rnaseq_utils_RNAseqDataset = {
  PyVarObject_HEAD_INIT(0, 0)
  "_rnaseq_utils.RNAseqDataset", /*tp_name*/
  sizeof(struct __pyx_obj_13_rnaseq_utils_RNAseqDataset), /*tp_basicsize*/
  0, /*tp_itemsize*/
  __pyx_tp_dealloc_13_rnaseq_utils_RNAseqDataset, /*tp_dealloc*/
  0, /*tp_print*/
  0, /*tp_getattr*/
  0, /*tp_setattr*/
  #if PY_MAJOR_VERSION < 3
  0, /*tp_compare*/
  #endif
  #if PY_MAJOR_VERSION >= 3
  0, /*tp_as_async*/
  #endif
  0, /*tp_repr*/
  0, /*tp_as_number*/
  0, /*tp_as_sequence*/
  0, /*tp_as_mapping*/
  0, /*tp_hash*/
  0, /*tp_call*/
  0, /*tp_str*/
  0, /*tp_getattro*/
  0, /*tp_setattro*/
  0, /*tp_as_buffer*/
  Py_TPFLAGS_DEFAULT|Py_TPFLAGS_HAVE_VERSION_TAG|Py_TPFLAGS_CHECKTYPES|Py_TPFLAGS_HAVE_NEWBUFFER|Py_TPFLAGS_BASETYPE|Py_TPFLAGS_HAVE_GC, /*tp_flags*/
  0, /*tp_doc*/
  __pyx_tp_traverse_13_rnaseq_utils_RNAseqDataset, /*tp_traverse*/
  __pyx_tp_clear_13_rnaseq_utils_RNAseqDataset, /*tp_clear*/
  0, /*tp_richcompare*/
  0, /*tp_weaklistoffset*/
  0, /*tp_iter*/
  0, /*tp_iternext*/
  __pyx_methods_13_rnaseq_utils_RNAseqDataset, /*tp_methods*/
  0, /*tp_members*/
  __pyx_getsets_13_rnaseq_utils_RNAseqDataset, /*tp_getset*/
  0, /*tp_base*/
  0, /*tp_dict*/
  0, /*tp_descr_get*/
  0, /*tp_descr_set*/
  0, /*tp_dictoffset*/
  __pyx_pw_13_rnaseq_utils_13RNAseqDataset_1__init__, /*tp_init*/
  0, /*tp_alloc*/
  __pyx_tp_new_13_rnaseq_utils_RNAseqDataset, /*tp_new*/
  0, /*tp_free*/
  0, /*tp_is_gc*/
  0, /*tp_bases*/
  0, /*tp_mro*/
  0, /*tp_cache*/
  0, /*tp_subclasses*/
  0, /*tp_weaklist*/
  0, /*tp_del*/
  0, /*tp_version_tag*/
  #if PY_VERSION_HEX >= 0x030400a1
  0, /*tp_finalize*/
  #endif
  #if PY_VERSION_HEX >= 0x030800b1
  0, /*tp_vectorcall*/
  #endif
};
static struct __pyx_vtabstruct_13_rnaseq_utils_AnnotationObject __pyx_vtable_13_rnaseq_utils_AnnotationObject;

static PyObject *__pyx_tp_new_13_rnaseq_utils_AnnotationObject(PyTypeObject *t, CYTHON_UNUSED PyObject *a, CYTHON_UNUSED PyObject *k) {
  struct __pyx_obj_13_rnaseq_utils_AnnotationObject *p;
  PyObject *o;
  if (likely((t->tp_flags & Py_TPFLAGS_IS_ABSTRACT) == 0)) {
    o = (*t->tp_alloc)(t, 0);
  } else {
    o = (PyObject *) PyBaseObject_Type.tp_new(t, __pyx_empty_tuple, 0);
  }
  if (unlikely(!o)) return 0;
  p = ((struct __pyx_obj_13_rnaseq_utils_AnnotationObject *)o);
  p->__pyx_vtab = __pyx_vtabptr_13_rnaseq_utils_AnnotationObject;
  p->attributes = ((PyObject*)Py_None); Py_INCREF(Py_None);
  p->format = ((PyObject*)Py_None); Py_INCREF(Py_None);
  p->gene_id = ((PyObject*)Py_None); Py_INCREF(Py_None);
  p->transcript_id = ((PyObject*)Py_None); Py_INCREF(Py_None);
  p->chrom = ((PyObject*)Py_None); Py_INCREF(Py_None);
  p->source = ((PyObject*)Py_None); Py_INCREF(Py_None);
  p->anno_type = ((PyObject*)Py_None); Py_INCREF(Py_None);
  p->fields = ((PyObject*)Py_None); Py_INCREF(Py_None);
  return o;
}

static void __pyx_tp_dealloc_13_rnaseq_utils_AnnotationObject(PyObject *o) {
  struct __pyx_obj_13_rnaseq_utils_AnnotationObject *p = (struct __pyx_obj_13_rnaseq_utils_AnnotationObject *)o;
  #if CYTHON_USE_TP_FINALIZE
  if (unlikely(PyType_HasFeature(Py_TYPE(o), Py_TPFLAGS_HAVE_FINALIZE) && Py_TYPE(o)->tp_finalize) && !_PyGC_FINALIZED(o)) {
    if (PyObject_CallFinalizerFromDealloc(o)) return;
  }
  #endif
  PyObject_GC_UnTrack(o);
  Py_CLEAR(p->attributes);
  Py_CLEAR(p->format);
  Py_CLEAR(p->gene_id);
  Py_CLEAR(p->transcript_id);
  Py_CLEAR(p->chrom);
  Py_CLEAR(p->source);
  Py_CLEAR(p->anno_type);
  Py_CLEAR(p->fields);
  (*Py_TYPE(o)->tp_free)(o);
}

static int __pyx_tp_traverse_13_rnaseq_utils_AnnotationObject(PyObject *o, visitproc v, void *a) {
  int e;
  struct __pyx_obj_13_rnaseq_utils_AnnotationObject *p = (struct __pyx_obj_13_rnaseq_utils_AnnotationObject *)o;
  if (p->attributes) {
    e = (*v)(p->attributes, a); if (e) return e;
  }
  if (p->fields) {
    e = (*v)(p->fields, a); if (e) return e;
  }
  return 0;
}

static int __pyx_tp_clear_13_rnaseq_utils_AnnotationObject(PyObject *o) {
  PyObject* tmp;
  struct __pyx_obj_13_rnaseq_utils_AnnotationObject *p = (struct __pyx_obj_13_rnaseq_utils_AnnotationObject *)o;
  tmp = ((PyObject*)p->attributes);
  p->attributes = ((PyObject*)Py_None); Py_INCREF(Py_None);
  Py_XDECREF(tmp);
  tmp = ((PyObject*)p->fields);
  p->fields = ((PyObject*)Py_None); Py_INCREF(Py_None);
  Py_XDECREF(tmp);
  return 0;
}

static PyObject *__pyx_tp_richcompare_13_rnaseq_utils_AnnotationObject(PyObject *o1, PyObject *o2, int op) {
  switch (op) {
    case Py_EQ: {
      return __pyx_pw_13_rnaseq_utils_16AnnotationObject_5__eq__(o1, o2);
    }
    case Py_NE: {
      return __pyx_pw_13_rnaseq_utils_16AnnotationObject_7__ne__(o1, o2);
    }
    case Py_LT: {
      return __pyx_pw_13_rnaseq_utils_16AnnotationObject_13__lt__(o1, o2);
    }
    case Py_GT: {
      return __pyx_pw_13_rnaseq_utils_16AnnotationObject_9__gt__(o1, o2);
    }
    case Py_LE: {
      return __pyx_pw_13_rnaseq_utils_16AnnotationObject_15__le__(o1, o2);
    }
    case Py_GE: {
      return __pyx_pw_13_rnaseq_utils_16AnnotationObject_11__ge__(o1, o2);
    }
    default: {
      return __Pyx_NewRef(Py_NotImplemented);
    }
  }
}

static PyObject *__pyx_getprop_13_rnaseq_utils_16AnnotationObject_attributes(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_16AnnotationObject_10attributes_1__get__(o);
}

static int __pyx_setprop_13_rnaseq_utils_16AnnotationObject_attributes(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
  if (v) {
    return __pyx_pw_13_rnaseq_utils_16AnnotationObject_10attributes_3__set__(o, v);
  }
  else {
    return __pyx_pw_13_rnaseq_utils_16AnnotationObject_10attributes_5__del__(o);
  }
}

static PyObject *__pyx_getprop_13_rnaseq_utils_16AnnotationObject_keep(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_16AnnotationObject_4keep_1__get__(o);
}

static int __pyx_setprop_13_rnaseq_utils_16AnnotationObject_keep(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
  if (v) {
    return __pyx_pw_13_rnaseq_utils_16AnnotationObject_4keep_3__set__(o, v);
  }
  else {
    PyErr_SetString(PyExc_NotImplementedError, "__del__");
    return -1;
  }
}

static PyObject *__pyx_getprop_13_rnaseq_utils_16AnnotationObject_parent(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_16AnnotationObject_6parent_1__get__(o);
}

static int __pyx_setprop_13_rnaseq_utils_16AnnotationObject_parent(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
  if (v) {
    return __pyx_pw_13_rnaseq_utils_16AnnotationObject_6parent_3__set__(o, v);
  }
  else {
    PyErr_SetString(PyExc_NotImplementedError, "__del__");
    return -1;
  }
}

static PyObject *__pyx_getprop_13_rnaseq_utils_16AnnotationObject_format(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_16AnnotationObject_6format_1__get__(o);
}

static int __pyx_setprop_13_rnaseq_utils_16AnnotationObject_format(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
  if (v) {
    return __pyx_pw_13_rnaseq_utils_16AnnotationObject_6format_3__set__(o, v);
  }
  else {
    return __pyx_pw_13_rnaseq_utils_16AnnotationObject_6format_5__del__(o);
  }
}

static PyObject *__pyx_getprop_13_rnaseq_utils_16AnnotationObject_gene_id(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_16AnnotationObject_7gene_id_1__get__(o);
}

static int __pyx_setprop_13_rnaseq_utils_16AnnotationObject_gene_id(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
  if (v) {
    return __pyx_pw_13_rnaseq_utils_16AnnotationObject_7gene_id_3__set__(o, v);
  }
  else {
    return __pyx_pw_13_rnaseq_utils_16AnnotationObject_7gene_id_5__del__(o);
  }
}

static PyObject *__pyx_getprop_13_rnaseq_utils_16AnnotationObject_transcript_id(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_16AnnotationObject_13transcript_id_1__get__(o);
}

static int __pyx_setprop_13_rnaseq_utils_16AnnotationObject_transcript_id(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
  if (v) {
    return __pyx_pw_13_rnaseq_utils_16AnnotationObject_13transcript_id_3__set__(o, v);
  }
  else {
    return __pyx_pw_13_rnaseq_utils_16AnnotationObject_13transcript_id_5__del__(o);
  }
}

static PyObject *__pyx_getprop_13_rnaseq_utils_16AnnotationObject_chrom(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_16AnnotationObject_5chrom_1__get__(o);
}

static int __pyx_setprop_13_rnaseq_utils_16AnnotationObject_chrom(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
  if (v) {
    return __pyx_pw_13_rnaseq_utils_16AnnotationObject_5chrom_3__set__(o, v);
  }
  else {
    return __pyx_pw_13_rnaseq_utils_16AnnotationObject_5chrom_5__del__(o);
  }
}

static PyObject *__pyx_getprop_13_rnaseq_utils_16AnnotationObject_source(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_16AnnotationObject_6source_1__get__(o);
}

static int __pyx_setprop_13_rnaseq_utils_16AnnotationObject_source(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
  if (v) {
    return __pyx_pw_13_rnaseq_utils_16AnnotationObject_6source_3__set__(o, v);
  }
  else {
    return __pyx_pw_13_rnaseq_utils_16AnnotationObject_6source_5__del__(o);
  }
}

static PyObject *__pyx_getprop_13_rnaseq_utils_16AnnotationObject_anno_type(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_16AnnotationObject_9anno_type_1__get__(o);
}

static int __pyx_setprop_13_rnaseq_utils_16AnnotationObject_anno_type(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
  if (v) {
    return __pyx_pw_13_rnaseq_utils_16AnnotationObject_9anno_type_3__set__(o, v);
  }
  else {
    return __pyx_pw_13_rnaseq_utils_16AnnotationObject_9anno_type_5__del__(o);
  }
}

static PyObject *__pyx_getprop_13_rnaseq_utils_16AnnotationObject_strand(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_16AnnotationObject_6strand_1__get__(o);
}

static int __pyx_setprop_13_rnaseq_utils_16AnnotationObject_strand(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
  if (v) {
    return __pyx_pw_13_rnaseq_utils_16AnnotationObject_6strand_3__set__(o, v);
  }
  else {
    PyErr_SetString(PyExc_NotImplementedError, "__del__");
    return -1;
  }
}

static PyObject *__pyx_getprop_13_rnaseq_utils_16AnnotationObject_span(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_16AnnotationObject_4span_1__get__(o);
}

static int __pyx_setprop_13_rnaseq_utils_16AnnotationObject_span(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
  if (v) {
    return __pyx_pw_13_rnaseq_utils_16AnnotationObject_4span_3__set__(o, v);
  }
  else {
    PyErr_SetString(PyExc_NotImplementedError, "__del__");
    return -1;
  }
}

static PyObject *__pyx_getprop_13_rnaseq_utils_16AnnotationObject_fields(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_16AnnotationObject_6fields_1__get__(o);
}

static int __pyx_setprop_13_rnaseq_utils_16AnnotationObject_fields(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
  if (v) {
    return __pyx_pw_13_rnaseq_utils_16AnnotationObject_6fields_3__set__(o, v);
  }
  else {
    return __pyx_pw_13_rnaseq_utils_16AnnotationObject_6fields_5__del__(o);
  }
}

static PyMethodDef __pyx_methods_13_rnaseq_utils_AnnotationObject[] = {
  {"parse_attributes", (PyCFunction)(void*)(PyCFunctionWithKeywords)__pyx_pw_13_rnaseq_utils_16AnnotationObject_3parse_attributes, METH_VARARGS|METH_KEYWORDS, __pyx_doc_13_rnaseq_utils_16AnnotationObject_2parse_attributes},
  {"__reduce_cython__", (PyCFunction)__pyx_pw_13_rnaseq_utils_16AnnotationObject_17__reduce_cython__, METH_NOARGS, 0},
  {"__setstate_cython__", (PyCFunction)__pyx_pw_13_rnaseq_utils_16AnnotationObject_19__setstate_cython__, METH_O, 0},
  {0, 0, 0, 0}
};

static struct PyGetSetDef __pyx_getsets_13_rnaseq_utils_AnnotationObject[] = {
  {(char *)"attributes", __pyx_getprop_13_rnaseq_utils_16AnnotationObject_attributes, __pyx_setprop_13_rnaseq_utils_16AnnotationObject_attributes, (char *)0, 0},
  {(char *)"keep", __pyx_getprop_13_rnaseq_utils_16AnnotationObject_keep, __pyx_setprop_13_rnaseq_utils_16AnnotationObject_keep, (char *)0, 0},
  {(char *)"parent", __pyx_getprop_13_rnaseq_utils_16AnnotationObject_parent, __pyx_setprop_13_rnaseq_utils_16AnnotationObject_parent, (char *)0, 0},
  {(char *)"format", __pyx_getprop_13_rnaseq_utils_16AnnotationObject_format, __pyx_setprop_13_rnaseq_utils_16AnnotationObject_format, (char *)0, 0},
  {(char *)"gene_id", __pyx_getprop_13_rnaseq_utils_16AnnotationObject_gene_id, __pyx_setprop_13_rnaseq_utils_16AnnotationObject_gene_id, (char *)0, 0},
  {(char *)"transcript_id", __pyx_getprop_13_rnaseq_utils_16AnnotationObject_transcript_id, __pyx_setprop_13_rnaseq_utils_16AnnotationObject_transcript_id, (char *)0, 0},
  {(char *)"chrom", __pyx_getprop_13_rnaseq_utils_16AnnotationObject_chrom, __pyx_setprop_13_rnaseq_utils_16AnnotationObject_chrom, (char *)0, 0},
  {(char *)"source", __pyx_getprop_13_rnaseq_utils_16AnnotationObject_source, __pyx_setprop_13_rnaseq_utils_16AnnotationObject_source, (char *)0, 0},
  {(char *)"anno_type", __pyx_getprop_13_rnaseq_utils_16AnnotationObject_anno_type, __pyx_setprop_13_rnaseq_utils_16AnnotationObject_anno_type, (char *)0, 0},
  {(char *)"strand", __pyx_getprop_13_rnaseq_utils_16AnnotationObject_strand, __pyx_setprop_13_rnaseq_utils_16AnnotationObject_strand, (char *)0, 0},
  {(char *)"span", __pyx_getprop_13_rnaseq_utils_16AnnotationObject_span, __pyx_setprop_13_rnaseq_utils_16AnnotationObject_span, (char *)0, 0},
  {(char *)"fields", __pyx_getprop_13_rnaseq_utils_16AnnotationObject_fields, __pyx_setprop_13_rnaseq_utils_16AnnotationObject_fields, (char *)0, 0},
  {0, 0, 0, 0, 0}
};

static PyTypeObject __pyx_type_13_rnaseq_utils_AnnotationObject = {
  PyVarObject_HEAD_INIT(0, 0)
  "_rnaseq_utils.AnnotationObject", /*tp_name*/
  sizeof(struct __pyx_obj_13_rnaseq_utils_AnnotationObject), /*tp_basicsize*/
  0, /*tp_itemsize*/
  __pyx_tp_dealloc_13_rnaseq_utils_AnnotationObject, /*tp_dealloc*/
  0, /*tp_print*/
  0, /*tp_getattr*/
  0, /*tp_setattr*/
  #if PY_MAJOR_VERSION < 3
  0, /*tp_compare*/
  #endif
  #if PY_MAJOR_VERSION >= 3
  0, /*tp_as_async*/
  #endif
  0, /*tp_repr*/
  0, /*tp_as_number*/
  0, /*tp_as_sequence*/
  0, /*tp_as_mapping*/
  0, /*tp_hash*/
  0, /*tp_call*/
  0, /*tp_str*/
  0, /*tp_getattro*/
  0, /*tp_setattro*/
  0, /*tp_as_buffer*/
  Py_TPFLAGS_DEFAULT|Py_TPFLAGS_HAVE_VERSION_TAG|Py_TPFLAGS_CHECKTYPES|Py_TPFLAGS_HAVE_NEWBUFFER|Py_TPFLAGS_BASETYPE|Py_TPFLAGS_HAVE_GC, /*tp_flags*/
  0, /*tp_doc*/
  __pyx_tp_traverse_13_rnaseq_utils_AnnotationObject, /*tp_traverse*/
  __pyx_tp_clear_13_rnaseq_utils_AnnotationObject, /*tp_clear*/
  __pyx_tp_richcompare_13_rnaseq_utils_AnnotationObject, /*tp_richcompare*/
  0, /*tp_weaklistoffset*/
  0, /*tp_iter*/
  0, /*tp_iternext*/
  __pyx_methods_13_rnaseq_utils_AnnotationObject, /*tp_methods*/
  0, /*tp_members*/
  __pyx_getsets_13_rnaseq_utils_AnnotationObject, /*tp_getset*/
  0, /*tp_base*/
  0, /*tp_dict*/
  0, /*tp_descr_get*/
  0, /*tp_descr_set*/
  0, /*tp_dictoffset*/
  __pyx_pw_13_rnaseq_utils_16AnnotationObject_1__init__, /*tp_init*/
  0, /*tp_alloc*/
  __pyx_tp_new_13_rnaseq_utils_AnnotationObject, /*tp_new*/
  0, /*tp_free*/
  0, /*tp_is_gc*/
  0, /*tp_bases*/
  0, /*tp_mro*/
  0, /*tp_cache*/
  0, /*tp_subclasses*/
  0, /*tp_weaklist*/
  0, /*tp_del*/
  0, /*tp_version_tag*/
  #if PY_VERSION_HEX >= 0x030400a1
  0, /*tp_finalize*/
  #endif
  #if PY_VERSION_HEX >= 0x030800b1
  0, /*tp_vectorcall*/
  #endif
};
static struct __pyx_vtabstruct_13_rnaseq_utils_AnnotationDataset __pyx_vtable_13_rnaseq_utils_AnnotationDataset;

static PyObject *__pyx_tp_new_13_rnaseq_utils_AnnotationDataset(PyTypeObject *t, PyObject *a, PyObject *k) {
  struct __pyx_obj_13_rnaseq_utils_AnnotationDataset *p;
  PyObject *o = __pyx_tp_new_13_rnaseq_utils_RNAseqDataset(t, a, k);
  if (unlikely(!o)) return 0;
  p = ((struct __pyx_obj_13_rnaseq_utils_AnnotationDataset *)o);
  p->__pyx_base.__pyx_vtab = (struct __pyx_vtabstruct_13_rnaseq_utils_RNAseqDataset*)__pyx_vtabptr_13_rnaseq_utils_AnnotationDataset;
  p->annotations = ((PyObject*)Py_None); Py_INCREF(Py_None);
  p->gtf_config = ((PyObject*)Py_None); Py_INCREF(Py_None);
  p->gff_config = ((PyObject*)Py_None); Py_INCREF(Py_None);
  p->generator = Py_None; Py_INCREF(Py_None);
  return o;
}

static void __pyx_tp_dealloc_13_rnaseq_utils_AnnotationDataset(PyObject *o) {
  struct __pyx_obj_13_rnaseq_utils_AnnotationDataset *p = (struct __pyx_obj_13_rnaseq_utils_AnnotationDataset *)o;
  #if CYTHON_USE_TP_FINALIZE
  if (unlikely(PyType_HasFeature(Py_TYPE(o), Py_TPFLAGS_HAVE_FINALIZE) && Py_TYPE(o)->tp_finalize) && !_PyGC_FINALIZED(o)) {
    if (PyObject_CallFinalizerFromDealloc(o)) return;
  }
  #endif
  PyObject_GC_UnTrack(o);
  Py_CLEAR(p->annotations);
  Py_CLEAR(p->gtf_config);
  Py_CLEAR(p->gff_config);
  Py_CLEAR(p->generator);
  PyObject_GC_Track(o);
  __pyx_tp_dealloc_13_rnaseq_utils_RNAseqDataset(o);
}

static int __pyx_tp_traverse_13_rnaseq_utils_AnnotationDataset(PyObject *o, visitproc v, void *a) {
  int e;
  struct __pyx_obj_13_rnaseq_utils_AnnotationDataset *p = (struct __pyx_obj_13_rnaseq_utils_AnnotationDataset *)o;
  e = __pyx_tp_traverse_13_rnaseq_utils_RNAseqDataset(o, v, a); if (e) return e;
  if (p->annotations) {
    e = (*v)(p->annotations, a); if (e) return e;
  }
  if (p->gtf_config) {
    e = (*v)(p->gtf_config, a); if (e) return e;
  }
  if (p->gff_config) {
    e = (*v)(p->gff_config, a); if (e) return e;
  }
  if (p->generator) {
    e = (*v)(p->generator, a); if (e) return e;
  }
  return 0;
}

static int __pyx_tp_clear_13_rnaseq_utils_AnnotationDataset(PyObject *o) {
  PyObject* tmp;
  struct __pyx_obj_13_rnaseq_utils_AnnotationDataset *p = (struct __pyx_obj_13_rnaseq_utils_AnnotationDataset *)o;
  __pyx_tp_clear_13_rnaseq_utils_RNAseqDataset(o);
  tmp = ((PyObject*)p->annotations);
  p->annotations = ((PyObject*)Py_None); Py_INCREF(Py_None);
  Py_XDECREF(tmp);
  tmp = ((PyObject*)p->gtf_config);
  p->gtf_config = ((PyObject*)Py_None); Py_INCREF(Py_None);
  Py_XDECREF(tmp);
  tmp = ((PyObject*)p->gff_config);
  p->gff_config = ((PyObject*)Py_None); Py_INCREF(Py_None);
  Py_XDECREF(tmp);
  tmp = ((PyObject*)p->generator);
  p->generator = Py_None; Py_INCREF(Py_None);
  Py_XDECREF(tmp);
  return 0;
}

static PyObject *__pyx_getprop_13_rnaseq_utils_17AnnotationDataset_annotations(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_17AnnotationDataset_11annotations_1__get__(o);
}

static int __pyx_setprop_13_rnaseq_utils_17AnnotationDataset_annotations(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
  if (v) {
    return __pyx_pw_13_rnaseq_utils_17AnnotationDataset_11annotations_3__set__(o, v);
  }
  else {
    return __pyx_pw_13_rnaseq_utils_17AnnotationDataset_11annotations_5__del__(o);
  }
}

static PyObject *__pyx_getprop_13_rnaseq_utils_17AnnotationDataset_gtf_config(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_17AnnotationDataset_10gtf_config_1__get__(o);
}

static int __pyx_setprop_13_rnaseq_utils_17AnnotationDataset_gtf_config(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
  if (v) {
    return __pyx_pw_13_rnaseq_utils_17AnnotationDataset_10gtf_config_3__set__(o, v);
  }
  else {
    return __pyx_pw_13_rnaseq_utils_17AnnotationDataset_10gtf_config_5__del__(o);
  }
}

static PyObject *__pyx_getprop_13_rnaseq_utils_17AnnotationDataset_gff_config(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_17AnnotationDataset_10gff_config_1__get__(o);
}

static int __pyx_setprop_13_rnaseq_utils_17AnnotationDataset_gff_config(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
  if (v) {
    return __pyx_pw_13_rnaseq_utils_17AnnotationDataset_10gff_config_3__set__(o, v);
  }
  else {
    return __pyx_pw_13_rnaseq_utils_17AnnotationDataset_10gff_config_5__del__(o);
  }
}

static PyObject *__pyx_getprop_13_rnaseq_utils_17AnnotationDataset_generator(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_17AnnotationDataset_9generator_1__get__(o);
}

static int __pyx_setprop_13_rnaseq_utils_17AnnotationDataset_generator(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
  if (v) {
    return __pyx_pw_13_rnaseq_utils_17AnnotationDataset_9generator_3__set__(o, v);
  }
  else {
    return __pyx_pw_13_rnaseq_utils_17AnnotationDataset_9generator_5__del__(o);
  }
}

static PyObject *__pyx_getprop_13_rnaseq_utils_17AnnotationDataset_number_of_assemblies(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_17AnnotationDataset_20number_of_assemblies_1__get__(o);
}

static int __pyx_setprop_13_rnaseq_utils_17AnnotationDataset_number_of_assemblies(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
  if (v) {
    return __pyx_pw_13_rnaseq_utils_17AnnotationDataset_20number_of_assemblies_3__set__(o, v);
  }
  else {
    PyErr_SetString(PyExc_NotImplementedError, "__del__");
    return -1;
  }
}

static PyObject *__pyx_getprop_13_rnaseq_utils_17AnnotationDataset_counter(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_17AnnotationDataset_7counter_1__get__(o);
}

static int __pyx_setprop_13_rnaseq_utils_17AnnotationDataset_counter(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
  if (v) {
    return __pyx_pw_13_rnaseq_utils_17AnnotationDataset_7counter_3__set__(o, v);
  }
  else {
    PyErr_SetString(PyExc_NotImplementedError, "__del__");
    return -1;
  }
}

static PyObject *__pyx_getprop_13_rnaseq_utils_17AnnotationDataset_min_reps(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_17AnnotationDataset_8min_reps_1__get__(o);
}

static int __pyx_setprop_13_rnaseq_utils_17AnnotationDataset_min_reps(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
  if (v) {
    return __pyx_pw_13_rnaseq_utils_17AnnotationDataset_8min_reps_3__set__(o, v);
  }
  else {
    PyErr_SetString(PyExc_NotImplementedError, "__del__");
    return -1;
  }
}

static PyObject *__pyx_getprop_13_rnaseq_utils_17AnnotationDataset_confidence(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_17AnnotationDataset_10confidence_1__get__(o);
}

static int __pyx_setprop_13_rnaseq_utils_17AnnotationDataset_confidence(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
  if (v) {
    return __pyx_pw_13_rnaseq_utils_17AnnotationDataset_10confidence_3__set__(o, v);
  }
  else {
    PyErr_SetString(PyExc_NotImplementedError, "__del__");
    return -1;
  }
}

static PyObject *__pyx_getprop_13_rnaseq_utils_17AnnotationDataset_cap_percent(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_17AnnotationDataset_11cap_percent_1__get__(o);
}

static int __pyx_setprop_13_rnaseq_utils_17AnnotationDataset_cap_percent(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
  if (v) {
    return __pyx_pw_13_rnaseq_utils_17AnnotationDataset_11cap_percent_3__set__(o, v);
  }
  else {
    PyErr_SetString(PyExc_NotImplementedError, "__del__");
    return -1;
  }
}

static PyObject *__pyx_getprop_13_rnaseq_utils_17AnnotationDataset_verbose(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_17AnnotationDataset_7verbose_1__get__(o);
}

static int __pyx_setprop_13_rnaseq_utils_17AnnotationDataset_verbose(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
  if (v) {
    return __pyx_pw_13_rnaseq_utils_17AnnotationDataset_7verbose_3__set__(o, v);
  }
  else {
    PyErr_SetString(PyExc_NotImplementedError, "__del__");
    return -1;
  }
}

static PyMethodDef __pyx_methods_13_rnaseq_utils_AnnotationDataset[] = {
  {"import_annotation", (PyCFunction)(void*)(PyCFunctionWithKeywords)__pyx_pw_13_rnaseq_utils_17AnnotationDataset_3import_annotation, METH_VARARGS|METH_KEYWORDS, __pyx_doc_13_rnaseq_utils_17AnnotationDataset_2import_annotation},
  {"get_transcript_fasta", (PyCFunction)__pyx_pw_13_rnaseq_utils_17AnnotationDataset_5get_transcript_fasta, METH_O, __pyx_doc_13_rnaseq_utils_17AnnotationDataset_4get_transcript_fasta},
  {"anno_to_mapping_object", (PyCFunction)(void*)(PyCFunctionWithKeywords)__pyx_pw_13_rnaseq_utils_17AnnotationDataset_7anno_to_mapping_object, METH_VARARGS|METH_KEYWORDS, __pyx_doc_13_rnaseq_utils_17AnnotationDataset_6anno_to_mapping_object},
  {"generate_loci", (PyCFunction)__pyx_pw_13_rnaseq_utils_17AnnotationDataset_9generate_loci, METH_NOARGS, __pyx_doc_13_rnaseq_utils_17AnnotationDataset_8generate_loci},
  {"__reduce_cython__", (PyCFunction)__pyx_pw_13_rnaseq_utils_17AnnotationDataset_12__reduce_cython__, METH_NOARGS, 0},
  {"__setstate_cython__", (PyCFunction)__pyx_pw_13_rnaseq_utils_17AnnotationDataset_14__setstate_cython__, METH_O, 0},
  {0, 0, 0, 0}
};

static struct PyGetSetDef __pyx_getsets_13_rnaseq_utils_AnnotationDataset[] = {
  {(char *)"annotations", __pyx_getprop_13_rnaseq_utils_17AnnotationDataset_annotations, __pyx_setprop_13_rnaseq_utils_17AnnotationDataset_annotations, (char *)0, 0},
  {(char *)"gtf_config", __pyx_getprop_13_rnaseq_utils_17AnnotationDataset_gtf_config, __pyx_setprop_13_rnaseq_utils_17AnnotationDataset_gtf_config, (char *)0, 0},
  {(char *)"gff_config", __pyx_getprop_13_rnaseq_utils_17AnnotationDataset_gff_config, __pyx_setprop_13_rnaseq_utils_17AnnotationDataset_gff_config, (char *)0, 0},
  {(char *)"generator", __pyx_getprop_13_rnaseq_utils_17AnnotationDataset_generator, __pyx_setprop_13_rnaseq_utils_17AnnotationDataset_generator, (char *)0, 0},
  {(char *)"number_of_assemblies", __pyx_getprop_13_rnaseq_utils_17AnnotationDataset_number_of_assemblies, __pyx_setprop_13_rnaseq_utils_17AnnotationDataset_number_of_assemblies, (char *)0, 0},
  {(char *)"counter", __pyx_getprop_13_rnaseq_utils_17AnnotationDataset_counter, __pyx_setprop_13_rnaseq_utils_17AnnotationDataset_counter, (char *)0, 0},
  {(char *)"min_reps", __pyx_getprop_13_rnaseq_utils_17AnnotationDataset_min_reps, __pyx_setprop_13_rnaseq_utils_17AnnotationDataset_min_reps, (char *)0, 0},
  {(char *)"confidence", __pyx_getprop_13_rnaseq_utils_17AnnotationDataset_confidence, __pyx_setprop_13_rnaseq_utils_17AnnotationDataset_confidence, (char *)0, 0},
  {(char *)"cap_percent", __pyx_getprop_13_rnaseq_utils_17AnnotationDataset_cap_percent, __pyx_setprop_13_rnaseq_utils_17AnnotationDataset_cap_percent, (char *)0, 0},
  {(char *)"verbose", __pyx_getprop_13_rnaseq_utils_17AnnotationDataset_verbose, __pyx_setprop_13_rnaseq_utils_17AnnotationDataset_verbose, (char *)0, 0},
  {0, 0, 0, 0, 0}
};

static PyTypeObject __pyx_type_13_rnaseq_utils_AnnotationDataset = {
  PyVarObject_HEAD_INIT(0, 0)
  "_rnaseq_utils.AnnotationDataset", /*tp_name*/
  sizeof(struct __pyx_obj_13_rnaseq_utils_AnnotationDataset), /*tp_basicsize*/
  0, /*tp_itemsize*/
  __pyx_tp_dealloc_13_rnaseq_utils_AnnotationDataset, /*tp_dealloc*/
  0, /*tp_print*/
  0, /*tp_getattr*/
  0, /*tp_setattr*/
  #if PY_MAJOR_VERSION < 3
  0, /*tp_compare*/
  #endif
  #if PY_MAJOR_VERSION >= 3
  0, /*tp_as_async*/
  #endif
  0, /*tp_repr*/
  0, /*tp_as_number*/
  0, /*tp_as_sequence*/
  0, /*tp_as_mapping*/
  0, /*tp_hash*/
  0, /*tp_call*/
  0, /*tp_str*/
  0, /*tp_getattro*/
  0, /*tp_setattro*/
  0, /*tp_as_buffer*/
  Py_TPFLAGS_DEFAULT|Py_TPFLAGS_HAVE_VERSION_TAG|Py_TPFLAGS_CHECKTYPES|Py_TPFLAGS_HAVE_NEWBUFFER|Py_TPFLAGS_BASETYPE|Py_TPFLAGS_HAVE_GC, /*tp_flags*/
  "Child of an RNAseqDataset. Parses a set of input annotations (GFF3/GTF/BED12/ELR).\n    Has methods that allow these annotations to be merged together to\n    form a single consensus or to be merged directly into a 'reference' annotation.", /*tp_doc*/
  __pyx_tp_traverse_13_rnaseq_utils_AnnotationDataset, /*tp_traverse*/
  __pyx_tp_clear_13_rnaseq_utils_AnnotationDataset, /*tp_clear*/
  0, /*tp_richcompare*/
  0, /*tp_weaklistoffset*/
  0, /*tp_iter*/
  0, /*tp_iternext*/
  __pyx_methods_13_rnaseq_utils_AnnotationDataset, /*tp_methods*/
  0, /*tp_members*/
  __pyx_getsets_13_rnaseq_utils_AnnotationDataset, /*tp_getset*/
  0, /*tp_base*/
  0, /*tp_dict*/
  0, /*tp_descr_get*/
  0, /*tp_descr_set*/
  0, /*tp_dictoffset*/
  __pyx_pw_13_rnaseq_utils_17AnnotationDataset_1__init__, /*tp_init*/
  0, /*tp_alloc*/
  __pyx_tp_new_13_rnaseq_utils_AnnotationDataset, /*tp_new*/
  0, /*tp_free*/
  0, /*tp_is_gc*/
  0, /*tp_bases*/
  0, /*tp_mro*/
  0, /*tp_cache*/
  0, /*tp_subclasses*/
  0, /*tp_weaklist*/
  0, /*tp_del*/
  0, /*tp_version_tag*/
  #if PY_VERSION_HEX >= 0x030400a1
  0, /*tp_finalize*/
  #endif
  #if PY_VERSION_HEX >= 0x030800b1
  0, /*tp_vectorcall*/
  #endif
};
static struct __pyx_vtabstruct_13_rnaseq_utils_BAMobject __pyx_vtable_13_rnaseq_utils_BAMobject;

static PyObject *__pyx_tp_new_13_rnaseq_utils_BAMobject(PyTypeObject *t, CYTHON_UNUSED PyObject *a, CYTHON_UNUSED PyObject *k) {
  struct __pyx_obj_13_rnaseq_utils_BAMobject *p;
  PyObject *o;
  if (likely((t->tp_flags & Py_TPFLAGS_IS_ABSTRACT) == 0)) {
    o = (*t->tp_alloc)(t, 0);
  } else {
    o = (PyObject *) PyBaseObject_Type.tp_new(t, __pyx_empty_tuple, 0);
  }
  if (unlikely(!o)) return 0;
  p = ((struct __pyx_obj_13_rnaseq_utils_BAMobject *)o);
  p->__pyx_vtab = __pyx_vtabptr_13_rnaseq_utils_BAMobject;
  p->dataset = ((struct __pyx_obj_13_rnaseq_utils_RNAseqDataset *)Py_None); Py_INCREF(Py_None);
  p->input_lines = ((PyObject*)Py_None); Py_INCREF(Py_None);
  return o;
}

static void __pyx_tp_dealloc_13_rnaseq_utils_BAMobject(PyObject *o) {
  struct __pyx_obj_13_rnaseq_utils_BAMobject *p = (struct __pyx_obj_13_rnaseq_utils_BAMobject *)o;
  #if CYTHON_USE_TP_FINALIZE
  if (unlikely(PyType_HasFeature(Py_TYPE(o), Py_TPFLAGS_HAVE_FINALIZE) && Py_TYPE(o)->tp_finalize) && !_PyGC_FINALIZED(o)) {
    if (PyObject_CallFinalizerFromDealloc(o)) return;
  }
  #endif
  PyObject_GC_UnTrack(o);
  Py_CLEAR(p->dataset);
  Py_CLEAR(p->input_lines);
  (*Py_TYPE(o)->tp_free)(o);
}

static int __pyx_tp_traverse_13_rnaseq_utils_BAMobject(PyObject *o, visitproc v, void *a) {
  int e;
  struct __pyx_obj_13_rnaseq_utils_BAMobject *p = (struct __pyx_obj_13_rnaseq_utils_BAMobject *)o;
  if (p->dataset) {
    e = (*v)(((PyObject *)p->dataset), a); if (e) return e;
  }
  if (p->input_lines) {
    e = (*v)(p->input_lines, a); if (e) return e;
  }
  return 0;
}

static int __pyx_tp_clear_13_rnaseq_utils_BAMobject(PyObject *o) {
  PyObject* tmp;
  struct __pyx_obj_13_rnaseq_utils_BAMobject *p = (struct __pyx_obj_13_rnaseq_utils_BAMobject *)o;
  tmp = ((PyObject*)p->dataset);
  p->dataset = ((struct __pyx_obj_13_rnaseq_utils_RNAseqDataset *)Py_None); Py_INCREF(Py_None);
  Py_XDECREF(tmp);
  tmp = ((PyObject*)p->input_lines);
  p->input_lines = ((PyObject*)Py_None); Py_INCREF(Py_None);
  Py_XDECREF(tmp);
  return 0;
}

static PyObject *__pyx_getprop_13_rnaseq_utils_9BAMobject_dataset(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_9BAMobject_7dataset_1__get__(o);
}

static PyObject *__pyx_getprop_13_rnaseq_utils_9BAMobject_input_lines(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_9BAMobject_11input_lines_1__get__(o);
}

static PyObject *__pyx_getprop_13_rnaseq_utils_9BAMobject_ignore_ends(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_9BAMobject_11ignore_ends_1__get__(o);
}

static PyObject *__pyx_getprop_13_rnaseq_utils_9BAMobject_secondary(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_9BAMobject_9secondary_1__get__(o);
}

static PyMethodDef __pyx_methods_13_rnaseq_utils_BAMobject[] = {
  {"generate_read", (PyCFunction)__pyx_pw_13_rnaseq_utils_9BAMobject_3generate_read, METH_NOARGS, 0},
  {"__reduce_cython__", (PyCFunction)__pyx_pw_13_rnaseq_utils_9BAMobject_5__reduce_cython__, METH_NOARGS, 0},
  {"__setstate_cython__", (PyCFunction)__pyx_pw_13_rnaseq_utils_9BAMobject_7__setstate_cython__, METH_O, 0},
  {0, 0, 0, 0}
};

static struct PyGetSetDef __pyx_getsets_13_rnaseq_utils_BAMobject[] = {
  {(char *)"dataset", __pyx_getprop_13_rnaseq_utils_9BAMobject_dataset, 0, (char *)0, 0},
  {(char *)"input_lines", __pyx_getprop_13_rnaseq_utils_9BAMobject_input_lines, 0, (char *)0, 0},
  {(char *)"ignore_ends", __pyx_getprop_13_rnaseq_utils_9BAMobject_ignore_ends, 0, (char *)0, 0},
  {(char *)"secondary", __pyx_getprop_13_rnaseq_utils_9BAMobject_secondary, 0, (char *)0, 0},
  {0, 0, 0, 0, 0}
};

static PyTypeObject __pyx_type_13_rnaseq_utils_BAMobject = {
  PyVarObject_HEAD_INIT(0, 0)
  "_rnaseq_utils.BAMobject", /*tp_name*/
  sizeof(struct __pyx_obj_13_rnaseq_utils_BAMobject), /*tp_basicsize*/
  0, /*tp_itemsize*/
  __pyx_tp_dealloc_13_rnaseq_utils_BAMobject, /*tp_dealloc*/
  0, /*tp_print*/
  0, /*tp_getattr*/
  0, /*tp_setattr*/
  #if PY_MAJOR_VERSION < 3
  0, /*tp_compare*/
  #endif
  #if PY_MAJOR_VERSION >= 3
  0, /*tp_as_async*/
  #endif
  0, /*tp_repr*/
  0, /*tp_as_number*/
  0, /*tp_as_sequence*/
  0, /*tp_as_mapping*/
  0, /*tp_hash*/
  0, /*tp_call*/
  0, /*tp_str*/
  0, /*tp_getattro*/
  0, /*tp_setattro*/
  0, /*tp_as_buffer*/
  Py_TPFLAGS_DEFAULT|Py_TPFLAGS_HAVE_VERSION_TAG|Py_TPFLAGS_CHECKTYPES|Py_TPFLAGS_HAVE_NEWBUFFER|Py_TPFLAGS_BASETYPE|Py_TPFLAGS_HAVE_GC, /*tp_flags*/
  0, /*tp_doc*/
  __pyx_tp_traverse_13_rnaseq_utils_BAMobject, /*tp_traverse*/
  __pyx_tp_clear_13_rnaseq_utils_BAMobject, /*tp_clear*/
  0, /*tp_richcompare*/
  0, /*tp_weaklistoffset*/
  0, /*tp_iter*/
  0, /*tp_iternext*/
  __pyx_methods_13_rnaseq_utils_BAMobject, /*tp_methods*/
  0, /*tp_members*/
  __pyx_getsets_13_rnaseq_utils_BAMobject, /*tp_getset*/
  0, /*tp_base*/
  0, /*tp_dict*/
  0, /*tp_descr_get*/
  0, /*tp_descr_set*/
  0, /*tp_dictoffset*/
  __pyx_pw_13_rnaseq_utils_9BAMobject_1__init__, /*tp_init*/
  0, /*tp_alloc*/
  __pyx_tp_new_13_rnaseq_utils_BAMobject, /*tp_new*/
  0, /*tp_free*/
  0, /*tp_is_gc*/
  0, /*tp_bases*/
  0, /*tp_mro*/
  0, /*tp_cache*/
  0, /*tp_subclasses*/
  0, /*tp_weaklist*/
  0, /*tp_del*/
  0, /*tp_version_tag*/
  #if PY_VERSION_HEX >= 0x030400a1
  0, /*tp_finalize*/
  #endif
  #if PY_VERSION_HEX >= 0x030800b1
  0, /*tp_vectorcall*/
  #endif
};
static struct __pyx_vtabstruct_13_rnaseq_utils_BranchpointArray __pyx_vtable_13_rnaseq_utils_BranchpointArray;

static PyObject *__pyx_tp_new_13_rnaseq_utils_BranchpointArray(PyTypeObject *t, CYTHON_UNUSED PyObject *a, CYTHON_UNUSED PyObject *k) {
  struct __pyx_obj_13_rnaseq_utils_BranchpointArray *p;
  PyObject *o;
  if (likely((t->tp_flags & Py_TPFLAGS_IS_ABSTRACT) == 0)) {
    o = (*t->tp_alloc)(t, 0);
  } else {
    o = (PyObject *) PyBaseObject_Type.tp_new(t, __pyx_empty_tuple, 0);
  }
  if (unlikely(!o)) return 0;
  p = ((struct __pyx_obj_13_rnaseq_utils_BranchpointArray *)o);
  p->__pyx_vtab = __pyx_vtabptr_13_rnaseq_utils_BranchpointArray;
  p->S_plus = ((PyObject*)Py_None); Py_INCREF(Py_None);
  p->S_minus = ((PyObject*)Py_None); Py_INCREF(Py_None);
  p->E_plus = ((PyObject*)Py_None); Py_INCREF(Py_None);
  p->E_minus = ((PyObject*)Py_None); Py_INCREF(Py_None);
  p->J_plus = ((PyObject*)Py_None); Py_INCREF(Py_None);
  p->J_minus = ((PyObject*)Py_None); Py_INCREF(Py_None);
  p->branchpoints = ((PyObject*)Py_None); Py_INCREF(Py_None);
  p->depth = ((PyArrayObject *)Py_None); Py_INCREF(Py_None);
  p->bp_plus = ((struct __pyx_obj_13_rnaseq_utils_OrderedArray *)Py_None); Py_INCREF(Py_None);
  p->bp_minus = ((struct __pyx_obj_13_rnaseq_utils_OrderedArray *)Py_None); Py_INCREF(Py_None);
  return o;
}

static void __pyx_tp_dealloc_13_rnaseq_utils_BranchpointArray(PyObject *o) {
  struct __pyx_obj_13_rnaseq_utils_BranchpointArray *p = (struct __pyx_obj_13_rnaseq_utils_BranchpointArray *)o;
  #if CYTHON_USE_TP_FINALIZE
  if (unlikely(PyType_HasFeature(Py_TYPE(o), Py_TPFLAGS_HAVE_FINALIZE) && Py_TYPE(o)->tp_finalize) && !_PyGC_FINALIZED(o)) {
    if (PyObject_CallFinalizerFromDealloc(o)) return;
  }
  #endif
  PyObject_GC_UnTrack(o);
  Py_CLEAR(p->S_plus);
  Py_CLEAR(p->S_minus);
  Py_CLEAR(p->E_plus);
  Py_CLEAR(p->E_minus);
  Py_CLEAR(p->J_plus);
  Py_CLEAR(p->J_minus);
  Py_CLEAR(p->branchpoints);
  Py_CLEAR(p->depth);
  Py_CLEAR(p->bp_plus);
  Py_CLEAR(p->bp_minus);
  (*Py_TYPE(o)->tp_free)(o);
}

static int __pyx_tp_traverse_13_rnaseq_utils_BranchpointArray(PyObject *o, visitproc v, void *a) {
  int e;
  struct __pyx_obj_13_rnaseq_utils_BranchpointArray *p = (struct __pyx_obj_13_rnaseq_utils_BranchpointArray *)o;
  if (p->S_plus) {
    e = (*v)(p->S_plus, a); if (e) return e;
  }
  if (p->S_minus) {
    e = (*v)(p->S_minus, a); if (e) return e;
  }
  if (p->E_plus) {
    e = (*v)(p->E_plus, a); if (e) return e;
  }
  if (p->E_minus) {
    e = (*v)(p->E_minus, a); if (e) return e;
  }
  if (p->J_plus) {
    e = (*v)(p->J_plus, a); if (e) return e;
  }
  if (p->J_minus) {
    e = (*v)(p->J_minus, a); if (e) return e;
  }
  if (p->branchpoints) {
    e = (*v)(p->branchpoints, a); if (e) return e;
  }
  if (p->depth) {
    e = (*v)(((PyObject *)p->depth), a); if (e) return e;
  }
  if (p->bp_plus) {
    e = (*v)(((PyObject *)p->bp_plus), a); if (e) return e;
  }
  if (p->bp_minus) {
    e = (*v)(((PyObject *)p->bp_minus), a); if (e) return e;
  }
  return 0;
}

static int __pyx_tp_clear_13_rnaseq_utils_BranchpointArray(PyObject *o) {
  PyObject* tmp;
  struct __pyx_obj_13_rnaseq_utils_BranchpointArray *p = (struct __pyx_obj_13_rnaseq_utils_BranchpointArray *)o;
  tmp = ((PyObject*)p->S_plus);
  p->S_plus = ((PyObject*)Py_None); Py_INCREF(Py_None);
  Py_XDECREF(tmp);
  tmp = ((PyObject*)p->S_minus);
  p->S_minus = ((PyObject*)Py_None); Py_INCREF(Py_None);
  Py_XDECREF(tmp);
  tmp = ((PyObject*)p->E_plus);
  p->E_plus = ((PyObject*)Py_None); Py_INCREF(Py_None);
  Py_XDECREF(tmp);
  tmp = ((PyObject*)p->E_minus);
  p->E_minus = ((PyObject*)Py_None); Py_INCREF(Py_None);
  Py_XDECREF(tmp);
  tmp = ((PyObject*)p->J_plus);
  p->J_plus = ((PyObject*)Py_None); Py_INCREF(Py_None);
  Py_XDECREF(tmp);
  tmp = ((PyObject*)p->J_minus);
  p->J_minus = ((PyObject*)Py_None); Py_INCREF(Py_None);
  Py_XDECREF(tmp);
  tmp = ((PyObject*)p->branchpoints);
  p->branchpoints = ((PyObject*)Py_None); Py_INCREF(Py_None);
  Py_XDECREF(tmp);
  tmp = ((PyObject*)p->depth);
  p->depth = ((PyArrayObject *)Py_None); Py_INCREF(Py_None);
  Py_XDECREF(tmp);
  tmp = ((PyObject*)p->bp_plus);
  p->bp_plus = ((struct __pyx_obj_13_rnaseq_utils_OrderedArray *)Py_None); Py_INCREF(Py_None);
  Py_XDECREF(tmp);
  tmp = ((PyObject*)p->bp_minus);
  p->bp_minus = ((struct __pyx_obj_13_rnaseq_utils_OrderedArray *)Py_None); Py_INCREF(Py_None);
  Py_XDECREF(tmp);
  return 0;
}

static PyObject *__pyx_getprop_13_rnaseq_utils_16BranchpointArray_S_plus(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_16BranchpointArray_6S_plus_1__get__(o);
}

static PyObject *__pyx_getprop_13_rnaseq_utils_16BranchpointArray_S_minus(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_16BranchpointArray_7S_minus_1__get__(o);
}

static PyObject *__pyx_getprop_13_rnaseq_utils_16BranchpointArray_E_plus(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_16BranchpointArray_6E_plus_1__get__(o);
}

static PyObject *__pyx_getprop_13_rnaseq_utils_16BranchpointArray_E_minus(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_16BranchpointArray_7E_minus_1__get__(o);
}

static PyObject *__pyx_getprop_13_rnaseq_utils_16BranchpointArray_J_plus(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_16BranchpointArray_6J_plus_1__get__(o);
}

static PyObject *__pyx_getprop_13_rnaseq_utils_16BranchpointArray_J_minus(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_16BranchpointArray_7J_minus_1__get__(o);
}

static PyObject *__pyx_getprop_13_rnaseq_utils_16BranchpointArray_leftmost(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_16BranchpointArray_8leftmost_1__get__(o);
}

static PyObject *__pyx_getprop_13_rnaseq_utils_16BranchpointArray_rightmost(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_16BranchpointArray_9rightmost_1__get__(o);
}

static PyObject *__pyx_getprop_13_rnaseq_utils_16BranchpointArray_extend(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_16BranchpointArray_6extend_1__get__(o);
}

static PyObject *__pyx_getprop_13_rnaseq_utils_16BranchpointArray_end_extend(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_16BranchpointArray_10end_extend_1__get__(o);
}

static PyObject *__pyx_getprop_13_rnaseq_utils_16BranchpointArray_length(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_16BranchpointArray_6length_1__get__(o);
}

static PyObject *__pyx_getprop_13_rnaseq_utils_16BranchpointArray_min_overhang(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_16BranchpointArray_12min_overhang_1__get__(o);
}

static PyObject *__pyx_getprop_13_rnaseq_utils_16BranchpointArray_branchpoints(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_16BranchpointArray_12branchpoints_1__get__(o);
}

static PyObject *__pyx_getprop_13_rnaseq_utils_16BranchpointArray_weight(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_16BranchpointArray_6weight_1__get__(o);
}

static PyObject *__pyx_getprop_13_rnaseq_utils_16BranchpointArray_threshold(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_16BranchpointArray_9threshold_1__get__(o);
}

static PyObject *__pyx_getprop_13_rnaseq_utils_16BranchpointArray_cap_percent(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_16BranchpointArray_11cap_percent_1__get__(o);
}

static PyObject *__pyx_getprop_13_rnaseq_utils_16BranchpointArray_minimum_proportion(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_16BranchpointArray_18minimum_proportion_1__get__(o);
}

static PyObject *__pyx_getprop_13_rnaseq_utils_16BranchpointArray_depth(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_16BranchpointArray_5depth_1__get__(o);
}

static PyObject *__pyx_getprop_13_rnaseq_utils_16BranchpointArray_bp_plus(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_16BranchpointArray_7bp_plus_1__get__(o);
}

static int __pyx_setprop_13_rnaseq_utils_16BranchpointArray_bp_plus(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
  if (v) {
    return __pyx_pw_13_rnaseq_utils_16BranchpointArray_7bp_plus_3__set__(o, v);
  }
  else {
    return __pyx_pw_13_rnaseq_utils_16BranchpointArray_7bp_plus_5__del__(o);
  }
}

static PyObject *__pyx_getprop_13_rnaseq_utils_16BranchpointArray_bp_minus(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_16BranchpointArray_8bp_minus_1__get__(o);
}

static int __pyx_setprop_13_rnaseq_utils_16BranchpointArray_bp_minus(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
  if (v) {
    return __pyx_pw_13_rnaseq_utils_16BranchpointArray_8bp_minus_3__set__(o, v);
  }
  else {
    return __pyx_pw_13_rnaseq_utils_16BranchpointArray_8bp_minus_5__del__(o);
  }
}

static PyObject *__pyx_getprop_13_rnaseq_utils_16BranchpointArray_infer_starts(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_16BranchpointArray_12infer_starts_1__get__(o);
}

static PyObject *__pyx_getprop_13_rnaseq_utils_16BranchpointArray_infer_ends(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_16BranchpointArray_10infer_ends_1__get__(o);
}

static PyObject *__pyx_getprop_13_rnaseq_utils_16BranchpointArray_use_attributes(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_16BranchpointArray_14use_attributes_1__get__(o);
}

static PyMethodDef __pyx_methods_13_rnaseq_utils_BranchpointArray[] = {
  {"bp_from_counter", (PyCFunction)(void*)(PyCFunctionWithKeywords)__pyx_pw_13_rnaseq_utils_16BranchpointArray_3bp_from_counter, METH_VARARGS|METH_KEYWORDS, __pyx_doc_13_rnaseq_utils_16BranchpointArray_2bp_from_counter},
  {"distance_from_edge", (PyCFunction)(void*)(PyCFunctionWithKeywords)__pyx_pw_13_rnaseq_utils_16BranchpointArray_5distance_from_edge, METH_VARARGS|METH_KEYWORDS, __pyx_doc_13_rnaseq_utils_16BranchpointArray_4distance_from_edge},
  {"add_endpoint", (PyCFunction)(void*)(PyCFunctionWithKeywords)__pyx_pw_13_rnaseq_utils_16BranchpointArray_7add_endpoint, METH_VARARGS|METH_KEYWORDS, __pyx_doc_13_rnaseq_utils_16BranchpointArray_6add_endpoint},
  {"infer_unknown_branchpoints", (PyCFunction)__pyx_pw_13_rnaseq_utils_16BranchpointArray_9infer_unknown_branchpoints, METH_O, __pyx_doc_13_rnaseq_utils_16BranchpointArray_8infer_unknown_branchpoints},
  {"remove_branchpoint", (PyCFunction)(void*)(PyCFunctionWithKeywords)__pyx_pw_13_rnaseq_utils_16BranchpointArray_11remove_branchpoint, METH_VARARGS|METH_KEYWORDS, __pyx_doc_13_rnaseq_utils_16BranchpointArray_10remove_branchpoint},
  {"__reduce_cython__", (PyCFunction)__pyx_pw_13_rnaseq_utils_16BranchpointArray_13__reduce_cython__, METH_NOARGS, 0},
  {"__setstate_cython__", (PyCFunction)__pyx_pw_13_rnaseq_utils_16BranchpointArray_15__setstate_cython__, METH_O, 0},
  {0, 0, 0, 0}
};

static struct PyGetSetDef __pyx_getsets_13_rnaseq_utils_BranchpointArray[] = {
  {(char *)"S_plus", __pyx_getprop_13_rnaseq_utils_16BranchpointArray_S_plus, 0, (char *)0, 0},
  {(char *)"S_minus", __pyx_getprop_13_rnaseq_utils_16BranchpointArray_S_minus, 0, (char *)0, 0},
  {(char *)"E_plus", __pyx_getprop_13_rnaseq_utils_16BranchpointArray_E_plus, 0, (char *)0, 0},
  {(char *)"E_minus", __pyx_getprop_13_rnaseq_utils_16BranchpointArray_E_minus, 0, (char *)0, 0},
  {(char *)"J_plus", __pyx_getprop_13_rnaseq_utils_16BranchpointArray_J_plus, 0, (char *)0, 0},
  {(char *)"J_minus", __pyx_getprop_13_rnaseq_utils_16BranchpointArray_J_minus, 0, (char *)0, 0},
  {(char *)"leftmost", __pyx_getprop_13_rnaseq_utils_16BranchpointArray_leftmost, 0, (char *)0, 0},
  {(char *)"rightmost", __pyx_getprop_13_rnaseq_utils_16BranchpointArray_rightmost, 0, (char *)0, 0},
  {(char *)"extend", __pyx_getprop_13_rnaseq_utils_16BranchpointArray_extend, 0, (char *)0, 0},
  {(char *)"end_extend", __pyx_getprop_13_rnaseq_utils_16BranchpointArray_end_extend, 0, (char *)0, 0},
  {(char *)"length", __pyx_getprop_13_rnaseq_utils_16BranchpointArray_length, 0, (char *)0, 0},
  {(char *)"min_overhang", __pyx_getprop_13_rnaseq_utils_16BranchpointArray_min_overhang, 0, (char *)0, 0},
  {(char *)"branchpoints", __pyx_getprop_13_rnaseq_utils_16BranchpointArray_branchpoints, 0, (char *)0, 0},
  {(char *)"weight", __pyx_getprop_13_rnaseq_utils_16BranchpointArray_weight, 0, (char *)0, 0},
  {(char *)"threshold", __pyx_getprop_13_rnaseq_utils_16BranchpointArray_threshold, 0, (char *)0, 0},
  {(char *)"cap_percent", __pyx_getprop_13_rnaseq_utils_16BranchpointArray_cap_percent, 0, (char *)0, 0},
  {(char *)"minimum_proportion", __pyx_getprop_13_rnaseq_utils_16BranchpointArray_minimum_proportion, 0, (char *)0, 0},
  {(char *)"depth", __pyx_getprop_13_rnaseq_utils_16BranchpointArray_depth, 0, (char *)0, 0},
  {(char *)"bp_plus", __pyx_getprop_13_rnaseq_utils_16BranchpointArray_bp_plus, __pyx_setprop_13_rnaseq_utils_16BranchpointArray_bp_plus, (char *)0, 0},
  {(char *)"bp_minus", __pyx_getprop_13_rnaseq_utils_16BranchpointArray_bp_minus, __pyx_setprop_13_rnaseq_utils_16BranchpointArray_bp_minus, (char *)0, 0},
  {(char *)"infer_starts", __pyx_getprop_13_rnaseq_utils_16BranchpointArray_infer_starts, 0, (char *)0, 0},
  {(char *)"infer_ends", __pyx_getprop_13_rnaseq_utils_16BranchpointArray_infer_ends, 0, (char *)0, 0},
  {(char *)"use_attributes", __pyx_getprop_13_rnaseq_utils_16BranchpointArray_use_attributes, 0, (char *)0, 0},
  {0, 0, 0, 0, 0}
};

static PyTypeObject __pyx_type_13_rnaseq_utils_BranchpointArray = {
  PyVarObject_HEAD_INIT(0, 0)
  "_rnaseq_utils.BranchpointArray", /*tp_name*/
  sizeof(struct __pyx_obj_13_rnaseq_utils_BranchpointArray), /*tp_basicsize*/
  0, /*tp_itemsize*/
  __pyx_tp_dealloc_13_rnaseq_utils_BranchpointArray, /*tp_dealloc*/
  0, /*tp_print*/
  0, /*tp_getattr*/
  0, /*tp_setattr*/
  #if PY_MAJOR_VERSION < 3
  0, /*tp_compare*/
  #endif
  #if PY_MAJOR_VERSION >= 3
  0, /*tp_as_async*/
  #endif
  0, /*tp_repr*/
  0, /*tp_as_number*/
  0, /*tp_as_sequence*/
  0, /*tp_as_mapping*/
  0, /*tp_hash*/
  0, /*tp_call*/
  0, /*tp_str*/
  0, /*tp_getattro*/
  0, /*tp_setattro*/
  0, /*tp_as_buffer*/
  Py_TPFLAGS_DEFAULT|Py_TPFLAGS_HAVE_VERSION_TAG|Py_TPFLAGS_CHECKTYPES|Py_TPFLAGS_HAVE_NEWBUFFER|Py_TPFLAGS_BASETYPE|Py_TPFLAGS_HAVE_GC, /*tp_flags*/
  0, /*tp_doc*/
  __pyx_tp_traverse_13_rnaseq_utils_BranchpointArray, /*tp_traverse*/
  __pyx_tp_clear_13_rnaseq_utils_BranchpointArray, /*tp_clear*/
  0, /*tp_richcompare*/
  0, /*tp_weaklistoffset*/
  0, /*tp_iter*/
  0, /*tp_iternext*/
  __pyx_methods_13_rnaseq_utils_BranchpointArray, /*tp_methods*/
  0, /*tp_members*/
  __pyx_getsets_13_rnaseq_utils_BranchpointArray, /*tp_getset*/
  0, /*tp_base*/
  0, /*tp_dict*/
  0, /*tp_descr_get*/
  0, /*tp_descr_set*/
  0, /*tp_dictoffset*/
  __pyx_pw_13_rnaseq_utils_16BranchpointArray_1__init__, /*tp_init*/
  0, /*tp_alloc*/
  __pyx_tp_new_13_rnaseq_utils_BranchpointArray, /*tp_new*/
  0, /*tp_free*/
  0, /*tp_is_gc*/
  0, /*tp_bases*/
  0, /*tp_mro*/
  0, /*tp_cache*/
  0, /*tp_subclasses*/
  0, /*tp_weaklist*/
  0, /*tp_del*/
  0, /*tp_version_tag*/
  #if PY_VERSION_HEX >= 0x030400a1
  0, /*tp_finalize*/
  #endif
  #if PY_VERSION_HEX >= 0x030800b1
  0, /*tp_vectorcall*/
  #endif
};
static struct __pyx_vtabstruct_13_rnaseq_utils_BranchPoint __pyx_vtable_13_rnaseq_utils_BranchPoint;

static PyObject *__pyx_tp_new_13_rnaseq_utils_BranchPoint(PyTypeObject *t, CYTHON_UNUSED PyObject *a, CYTHON_UNUSED PyObject *k) {
  struct __pyx_obj_13_rnaseq_utils_BranchPoint *p;
  PyObject *o;
  if (likely((t->tp_flags & Py_TPFLAGS_IS_ABSTRACT) == 0)) {
    o = (*t->tp_alloc)(t, 0);
  } else {
    o = (PyObject *) PyBaseObject_Type.tp_new(t, __pyx_empty_tuple, 0);
  }
  if (unlikely(!o)) return 0;
  p = ((struct __pyx_obj_13_rnaseq_utils_BranchPoint *)o);
  p->__pyx_vtab = __pyx_vtabptr_13_rnaseq_utils_BranchPoint;
  p->branchtype = ((PyObject*)Py_None); Py_INCREF(Py_None);
  return o;
}

static void __pyx_tp_dealloc_13_rnaseq_utils_BranchPoint(PyObject *o) {
  struct __pyx_obj_13_rnaseq_utils_BranchPoint *p = (struct __pyx_obj_13_rnaseq_utils_BranchPoint *)o;
  #if CYTHON_USE_TP_FINALIZE
  if (unlikely(PyType_HasFeature(Py_TYPE(o), Py_TPFLAGS_HAVE_FINALIZE) && Py_TYPE(o)->tp_finalize) && (!PyType_IS_GC(Py_TYPE(o)) || !_PyGC_FINALIZED(o))) {
    if (PyObject_CallFinalizerFromDealloc(o)) return;
  }
  #endif
  Py_CLEAR(p->branchtype);
  (*Py_TYPE(o)->tp_free)(o);
}

static PyObject *__pyx_tp_richcompare_13_rnaseq_utils_BranchPoint(PyObject *o1, PyObject *o2, int op) {
  switch (op) {
    case Py_EQ: {
      return __pyx_pw_13_rnaseq_utils_11BranchPoint_7__eq__(o1, o2);
    }
    case Py_NE: {
      return __pyx_pw_13_rnaseq_utils_11BranchPoint_9__ne__(o1, o2);
    }
    case Py_LT: {
      return __pyx_pw_13_rnaseq_utils_11BranchPoint_15__lt__(o1, o2);
    }
    case Py_GT: {
      return __pyx_pw_13_rnaseq_utils_11BranchPoint_11__gt__(o1, o2);
    }
    case Py_LE: {
      return __pyx_pw_13_rnaseq_utils_11BranchPoint_17__le__(o1, o2);
    }
    case Py_GE: {
      return __pyx_pw_13_rnaseq_utils_11BranchPoint_13__ge__(o1, o2);
    }
    default: {
      return __Pyx_NewRef(Py_NotImplemented);
    }
  }
}

static PyObject *__pyx_getprop_13_rnaseq_utils_11BranchPoint_branchtype(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_11BranchPoint_10branchtype_1__get__(o);
}

static PyObject *__pyx_getprop_13_rnaseq_utils_11BranchPoint_strand(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_11BranchPoint_6strand_1__get__(o);
}

static PyObject *__pyx_getprop_13_rnaseq_utils_11BranchPoint_pos(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_11BranchPoint_3pos_1__get__(o);
}

static int __pyx_setprop_13_rnaseq_utils_11BranchPoint_pos(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
  if (v) {
    return __pyx_pw_13_rnaseq_utils_11BranchPoint_3pos_3__set__(o, v);
  }
  else {
    PyErr_SetString(PyExc_NotImplementedError, "__del__");
    return -1;
  }
}

static PyObject *__pyx_getprop_13_rnaseq_utils_11BranchPoint_index(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_11BranchPoint_5index_1__get__(o);
}

static int __pyx_setprop_13_rnaseq_utils_11BranchPoint_index(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
  if (v) {
    return __pyx_pw_13_rnaseq_utils_11BranchPoint_5index_3__set__(o, v);
  }
  else {
    PyErr_SetString(PyExc_NotImplementedError, "__del__");
    return -1;
  }
}

static PyObject *__pyx_getprop_13_rnaseq_utils_11BranchPoint_left(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_11BranchPoint_4left_1__get__(o);
}

static int __pyx_setprop_13_rnaseq_utils_11BranchPoint_left(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
  if (v) {
    return __pyx_pw_13_rnaseq_utils_11BranchPoint_4left_3__set__(o, v);
  }
  else {
    PyErr_SetString(PyExc_NotImplementedError, "__del__");
    return -1;
  }
}

static PyObject *__pyx_getprop_13_rnaseq_utils_11BranchPoint_right(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_11BranchPoint_5right_1__get__(o);
}

static int __pyx_setprop_13_rnaseq_utils_11BranchPoint_right(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
  if (v) {
    return __pyx_pw_13_rnaseq_utils_11BranchPoint_5right_3__set__(o, v);
  }
  else {
    PyErr_SetString(PyExc_NotImplementedError, "__del__");
    return -1;
  }
}

static PyObject *__pyx_getprop_13_rnaseq_utils_11BranchPoint_weight(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_11BranchPoint_6weight_1__get__(o);
}

static int __pyx_setprop_13_rnaseq_utils_11BranchPoint_weight(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
  if (v) {
    return __pyx_pw_13_rnaseq_utils_11BranchPoint_6weight_3__set__(o, v);
  }
  else {
    PyErr_SetString(PyExc_NotImplementedError, "__del__");
    return -1;
  }
}

static PyObject *__pyx_getprop_13_rnaseq_utils_11BranchPoint_comparator(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_11BranchPoint_10comparator_1__get__(o);
}

static int __pyx_setprop_13_rnaseq_utils_11BranchPoint_comparator(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
  if (v) {
    return __pyx_pw_13_rnaseq_utils_11BranchPoint_10comparator_3__set__(o, v);
  }
  else {
    PyErr_SetString(PyExc_NotImplementedError, "__del__");
    return -1;
  }
}

static PyMethodDef __pyx_methods_13_rnaseq_utils_BranchPoint[] = {
  {"percent_capped", (PyCFunction)__pyx_pw_13_rnaseq_utils_11BranchPoint_3percent_capped, METH_NOARGS, 0},
  {"write_as_bed", (PyCFunction)__pyx_pw_13_rnaseq_utils_11BranchPoint_19write_as_bed, METH_O, 0},
  {"__reduce_cython__", (PyCFunction)__pyx_pw_13_rnaseq_utils_11BranchPoint_21__reduce_cython__, METH_NOARGS, 0},
  {"__setstate_cython__", (PyCFunction)__pyx_pw_13_rnaseq_utils_11BranchPoint_23__setstate_cython__, METH_O, 0},
  {0, 0, 0, 0}
};

static struct PyGetSetDef __pyx_getsets_13_rnaseq_utils_BranchPoint[] = {
  {(char *)"branchtype", __pyx_getprop_13_rnaseq_utils_11BranchPoint_branchtype, 0, (char *)0, 0},
  {(char *)"strand", __pyx_getprop_13_rnaseq_utils_11BranchPoint_strand, 0, (char *)0, 0},
  {(char *)"pos", __pyx_getprop_13_rnaseq_utils_11BranchPoint_pos, __pyx_setprop_13_rnaseq_utils_11BranchPoint_pos, (char *)0, 0},
  {(char *)"index", __pyx_getprop_13_rnaseq_utils_11BranchPoint_index, __pyx_setprop_13_rnaseq_utils_11BranchPoint_index, (char *)0, 0},
  {(char *)"left", __pyx_getprop_13_rnaseq_utils_11BranchPoint_left, __pyx_setprop_13_rnaseq_utils_11BranchPoint_left, (char *)0, 0},
  {(char *)"right", __pyx_getprop_13_rnaseq_utils_11BranchPoint_right, __pyx_setprop_13_rnaseq_utils_11BranchPoint_right, (char *)0, 0},
  {(char *)"weight", __pyx_getprop_13_rnaseq_utils_11BranchPoint_weight, __pyx_setprop_13_rnaseq_utils_11BranchPoint_weight, (char *)0, 0},
  {(char *)"comparator", __pyx_getprop_13_rnaseq_utils_11BranchPoint_comparator, __pyx_setprop_13_rnaseq_utils_11BranchPoint_comparator, (char *)0, 0},
  {0, 0, 0, 0, 0}
};

static PyTypeObject __pyx_type_13_rnaseq_utils_BranchPoint = {
  PyVarObject_HEAD_INIT(0, 0)
  "_rnaseq_utils.BranchPoint", /*tp_name*/
  sizeof(struct __pyx_obj_13_rnaseq_utils_BranchPoint), /*tp_basicsize*/
  0, /*tp_itemsize*/
  __pyx_tp_dealloc_13_rnaseq_utils_BranchPoint, /*tp_dealloc*/
  0, /*tp_print*/
  0, /*tp_getattr*/
  0, /*tp_setattr*/
  #if PY_MAJOR_VERSION < 3
  0, /*tp_compare*/
  #endif
  #if PY_MAJOR_VERSION >= 3
  0, /*tp_as_async*/
  #endif
  __pyx_pw_13_rnaseq_utils_11BranchPoint_5__repr__, /*tp_repr*/
  0, /*tp_as_number*/
  0, /*tp_as_sequence*/
  0, /*tp_as_mapping*/
  0, /*tp_hash*/
  0, /*tp_call*/
  0, /*tp_str*/
  0, /*tp_getattro*/
  0, /*tp_setattro*/
  0, /*tp_as_buffer*/
  Py_TPFLAGS_DEFAULT|Py_TPFLAGS_HAVE_VERSION_TAG|Py_TPFLAGS_CHECKTYPES|Py_TPFLAGS_HAVE_NEWBUFFER|Py_TPFLAGS_BASETYPE, /*tp_flags*/
  "Represents a reference point for a Start, End, Donor, or Acceptor site.", /*tp_doc*/
  0, /*tp_traverse*/
  0, /*tp_clear*/
  __pyx_tp_richcompare_13_rnaseq_utils_BranchPoint, /*tp_richcompare*/
  0, /*tp_weaklistoffset*/
  0, /*tp_iter*/
  0, /*tp_iternext*/
  __pyx_methods_13_rnaseq_utils_BranchPoint, /*tp_methods*/
  0, /*tp_members*/
  __pyx_getsets_13_rnaseq_utils_BranchPoint, /*tp_getset*/
  0, /*tp_base*/
  0, /*tp_dict*/
  0, /*tp_descr_get*/
  0, /*tp_descr_set*/
  0, /*tp_dictoffset*/
  __pyx_pw_13_rnaseq_utils_11BranchPoint_1__init__, /*tp_init*/
  0, /*tp_alloc*/
  __pyx_tp_new_13_rnaseq_utils_BranchPoint, /*tp_new*/
  0, /*tp_free*/
  0, /*tp_is_gc*/
  0, /*tp_bases*/
  0, /*tp_mro*/
  0, /*tp_cache*/
  0, /*tp_subclasses*/
  0, /*tp_weaklist*/
  0, /*tp_del*/
  0, /*tp_version_tag*/
  #if PY_VERSION_HEX >= 0x030400a1
  0, /*tp_finalize*/
  #endif
  #if PY_VERSION_HEX >= 0x030800b1
  0, /*tp_vectorcall*/
  #endif
};
static struct __pyx_vtabstruct_13_rnaseq_utils_StartPoint __pyx_vtable_13_rnaseq_utils_StartPoint;

static PyObject *__pyx_tp_new_13_rnaseq_utils_StartPoint(PyTypeObject *t, PyObject *a, PyObject *k) {
  struct __pyx_obj_13_rnaseq_utils_StartPoint *p;
  PyObject *o = __pyx_tp_new_13_rnaseq_utils_BranchPoint(t, a, k);
  if (unlikely(!o)) return 0;
  p = ((struct __pyx_obj_13_rnaseq_utils_StartPoint *)o);
  p->__pyx_base.__pyx_vtab = (struct __pyx_vtabstruct_13_rnaseq_utils_BranchPoint*)__pyx_vtabptr_13_rnaseq_utils_StartPoint;
  p->span = Py_None; Py_INCREF(Py_None);
  return o;
}

static void __pyx_tp_dealloc_13_rnaseq_utils_StartPoint(PyObject *o) {
  struct __pyx_obj_13_rnaseq_utils_StartPoint *p = (struct __pyx_obj_13_rnaseq_utils_StartPoint *)o;
  #if CYTHON_USE_TP_FINALIZE
  if (unlikely(PyType_HasFeature(Py_TYPE(o), Py_TPFLAGS_HAVE_FINALIZE) && Py_TYPE(o)->tp_finalize) && !_PyGC_FINALIZED(o)) {
    if (PyObject_CallFinalizerFromDealloc(o)) return;
  }
  #endif
  PyObject_GC_UnTrack(o);
  Py_CLEAR(p->span);
  #if CYTHON_USE_TYPE_SLOTS
  if (PyType_IS_GC(Py_TYPE(o)->tp_base))
  #endif
  PyObject_GC_Track(o);
  __pyx_tp_dealloc_13_rnaseq_utils_BranchPoint(o);
}

static int __pyx_tp_traverse_13_rnaseq_utils_StartPoint(PyObject *o, visitproc v, void *a) {
  int e;
  struct __pyx_obj_13_rnaseq_utils_StartPoint *p = (struct __pyx_obj_13_rnaseq_utils_StartPoint *)o;
  e = ((likely(__pyx_ptype_13_rnaseq_utils_BranchPoint)) ? ((__pyx_ptype_13_rnaseq_utils_BranchPoint->tp_traverse) ? __pyx_ptype_13_rnaseq_utils_BranchPoint->tp_traverse(o, v, a) : 0) : __Pyx_call_next_tp_traverse(o, v, a, __pyx_tp_traverse_13_rnaseq_utils_StartPoint)); if (e) return e;
  if (p->span) {
    e = (*v)(p->span, a); if (e) return e;
  }
  return 0;
}

static int __pyx_tp_clear_13_rnaseq_utils_StartPoint(PyObject *o) {
  PyObject* tmp;
  struct __pyx_obj_13_rnaseq_utils_StartPoint *p = (struct __pyx_obj_13_rnaseq_utils_StartPoint *)o;
  if (likely(__pyx_ptype_13_rnaseq_utils_BranchPoint)) { if (__pyx_ptype_13_rnaseq_utils_BranchPoint->tp_clear) __pyx_ptype_13_rnaseq_utils_BranchPoint->tp_clear(o); } else __Pyx_call_next_tp_clear(o, __pyx_tp_clear_13_rnaseq_utils_StartPoint);
  tmp = ((PyObject*)p->span);
  p->span = Py_None; Py_INCREF(Py_None);
  Py_XDECREF(tmp);
  return 0;
}

static PyObject *__pyx_getprop_13_rnaseq_utils_10StartPoint_extend(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_10StartPoint_6extend_1__get__(o);
}

static int __pyx_setprop_13_rnaseq_utils_10StartPoint_extend(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
  if (v) {
    return __pyx_pw_13_rnaseq_utils_10StartPoint_6extend_3__set__(o, v);
  }
  else {
    PyErr_SetString(PyExc_NotImplementedError, "__del__");
    return -1;
  }
}

static PyObject *__pyx_getprop_13_rnaseq_utils_10StartPoint_span(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_10StartPoint_4span_1__get__(o);
}

static int __pyx_setprop_13_rnaseq_utils_10StartPoint_span(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
  if (v) {
    return __pyx_pw_13_rnaseq_utils_10StartPoint_4span_3__set__(o, v);
  }
  else {
    return __pyx_pw_13_rnaseq_utils_10StartPoint_4span_5__del__(o);
  }
}

static PyObject *__pyx_getprop_13_rnaseq_utils_10StartPoint_capped(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_10StartPoint_6capped_1__get__(o);
}

static int __pyx_setprop_13_rnaseq_utils_10StartPoint_capped(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
  if (v) {
    return __pyx_pw_13_rnaseq_utils_10StartPoint_6capped_3__set__(o, v);
  }
  else {
    PyErr_SetString(PyExc_NotImplementedError, "__del__");
    return -1;
  }
}

static PyMethodDef __pyx_methods_13_rnaseq_utils_StartPoint[] = {
  {"percent_capped", (PyCFunction)__pyx_pw_13_rnaseq_utils_10StartPoint_3percent_capped, METH_NOARGS, 0},
  {"merge", (PyCFunction)__pyx_pw_13_rnaseq_utils_10StartPoint_5merge, METH_O, __pyx_doc_13_rnaseq_utils_10StartPoint_4merge},
  {"__reduce_cython__", (PyCFunction)__pyx_pw_13_rnaseq_utils_10StartPoint_7__reduce_cython__, METH_NOARGS, 0},
  {"__setstate_cython__", (PyCFunction)__pyx_pw_13_rnaseq_utils_10StartPoint_9__setstate_cython__, METH_O, 0},
  {0, 0, 0, 0}
};

static struct PyGetSetDef __pyx_getsets_13_rnaseq_utils_StartPoint[] = {
  {(char *)"extend", __pyx_getprop_13_rnaseq_utils_10StartPoint_extend, __pyx_setprop_13_rnaseq_utils_10StartPoint_extend, (char *)0, 0},
  {(char *)"span", __pyx_getprop_13_rnaseq_utils_10StartPoint_span, __pyx_setprop_13_rnaseq_utils_10StartPoint_span, (char *)0, 0},
  {(char *)"capped", __pyx_getprop_13_rnaseq_utils_10StartPoint_capped, __pyx_setprop_13_rnaseq_utils_10StartPoint_capped, (char *)0, 0},
  {0, 0, 0, 0, 0}
};

static PyTypeObject __pyx_type_13_rnaseq_utils_StartPoint = {
  PyVarObject_HEAD_INIT(0, 0)
  "_rnaseq_utils.StartPoint", /*tp_name*/
  sizeof(struct __pyx_obj_13_rnaseq_utils_StartPoint), /*tp_basicsize*/
  0, /*tp_itemsize*/
  __pyx_tp_dealloc_13_rnaseq_utils_StartPoint, /*tp_dealloc*/
  0, /*tp_print*/
  0, /*tp_getattr*/
  0, /*tp_setattr*/
  #if PY_MAJOR_VERSION < 3
  0, /*tp_compare*/
  #endif
  #if PY_MAJOR_VERSION >= 3
  0, /*tp_as_async*/
  #endif
  #if CYTHON_COMPILING_IN_PYPY
  __pyx_pw_13_rnaseq_utils_11BranchPoint_5__repr__, /*tp_repr*/
  #else
  0, /*tp_repr*/
  #endif
  0, /*tp_as_number*/
  0, /*tp_as_sequence*/
  0, /*tp_as_mapping*/
  0, /*tp_hash*/
  0, /*tp_call*/
  0, /*tp_str*/
  0, /*tp_getattro*/
  0, /*tp_setattro*/
  0, /*tp_as_buffer*/
  Py_TPFLAGS_DEFAULT|Py_TPFLAGS_HAVE_VERSION_TAG|Py_TPFLAGS_CHECKTYPES|Py_TPFLAGS_HAVE_NEWBUFFER|Py_TPFLAGS_BASETYPE|Py_TPFLAGS_HAVE_GC, /*tp_flags*/
  "Represents a transcript start site", /*tp_doc*/
  __pyx_tp_traverse_13_rnaseq_utils_StartPoint, /*tp_traverse*/
  __pyx_tp_clear_13_rnaseq_utils_StartPoint, /*tp_clear*/
  0, /*tp_richcompare*/
  0, /*tp_weaklistoffset*/
  0, /*tp_iter*/
  0, /*tp_iternext*/
  __pyx_methods_13_rnaseq_utils_StartPoint, /*tp_methods*/
  0, /*tp_members*/
  __pyx_getsets_13_rnaseq_utils_StartPoint, /*tp_getset*/
  0, /*tp_base*/
  0, /*tp_dict*/
  0, /*tp_descr_get*/
  0, /*tp_descr_set*/
  0, /*tp_dictoffset*/
  __pyx_pw_13_rnaseq_utils_10StartPoint_1__init__, /*tp_init*/
  0, /*tp_alloc*/
  __pyx_tp_new_13_rnaseq_utils_StartPoint, /*tp_new*/
  0, /*tp_free*/
  0, /*tp_is_gc*/
  0, /*tp_bases*/
  0, /*tp_mro*/
  0, /*tp_cache*/
  0, /*tp_subclasses*/
  0, /*tp_weaklist*/
  0, /*tp_del*/
  0, /*tp_version_tag*/
  #if PY_VERSION_HEX >= 0x030400a1
  0, /*tp_finalize*/
  #endif
  #if PY_VERSION_HEX >= 0x030800b1
  0, /*tp_vectorcall*/
  #endif
};
static struct __pyx_vtabstruct_13_rnaseq_utils_EndPoint __pyx_vtable_13_rnaseq_utils_EndPoint;

static PyObject *__pyx_tp_new_13_rnaseq_utils_EndPoint(PyTypeObject *t, PyObject *a, PyObject *k) {
  struct __pyx_obj_13_rnaseq_utils_EndPoint *p;
  PyObject *o = __pyx_tp_new_13_rnaseq_utils_BranchPoint(t, a, k);
  if (unlikely(!o)) return 0;
  p = ((struct __pyx_obj_13_rnaseq_utils_EndPoint *)o);
  p->__pyx_base.__pyx_vtab = (struct __pyx_vtabstruct_13_rnaseq_utils_BranchPoint*)__pyx_vtabptr_13_rnaseq_utils_EndPoint;
  p->span = Py_None; Py_INCREF(Py_None);
  return o;
}

static void __pyx_tp_dealloc_13_rnaseq_utils_EndPoint(PyObject *o) {
  struct __pyx_obj_13_rnaseq_utils_EndPoint *p = (struct __pyx_obj_13_rnaseq_utils_EndPoint *)o;
  #if CYTHON_USE_TP_FINALIZE
  if (unlikely(PyType_HasFeature(Py_TYPE(o), Py_TPFLAGS_HAVE_FINALIZE) && Py_TYPE(o)->tp_finalize) && !_PyGC_FINALIZED(o)) {
    if (PyObject_CallFinalizerFromDealloc(o)) return;
  }
  #endif
  PyObject_GC_UnTrack(o);
  Py_CLEAR(p->span);
  #if CYTHON_USE_TYPE_SLOTS
  if (PyType_IS_GC(Py_TYPE(o)->tp_base))
  #endif
  PyObject_GC_Track(o);
  __pyx_tp_dealloc_13_rnaseq_utils_BranchPoint(o);
}

static int __pyx_tp_traverse_13_rnaseq_utils_EndPoint(PyObject *o, visitproc v, void *a) {
  int e;
  struct __pyx_obj_13_rnaseq_utils_EndPoint *p = (struct __pyx_obj_13_rnaseq_utils_EndPoint *)o;
  e = ((likely(__pyx_ptype_13_rnaseq_utils_BranchPoint)) ? ((__pyx_ptype_13_rnaseq_utils_BranchPoint->tp_traverse) ? __pyx_ptype_13_rnaseq_utils_BranchPoint->tp_traverse(o, v, a) : 0) : __Pyx_call_next_tp_traverse(o, v, a, __pyx_tp_traverse_13_rnaseq_utils_EndPoint)); if (e) return e;
  if (p->span) {
    e = (*v)(p->span, a); if (e) return e;
  }
  return 0;
}

static int __pyx_tp_clear_13_rnaseq_utils_EndPoint(PyObject *o) {
  PyObject* tmp;
  struct __pyx_obj_13_rnaseq_utils_EndPoint *p = (struct __pyx_obj_13_rnaseq_utils_EndPoint *)o;
  if (likely(__pyx_ptype_13_rnaseq_utils_BranchPoint)) { if (__pyx_ptype_13_rnaseq_utils_BranchPoint->tp_clear) __pyx_ptype_13_rnaseq_utils_BranchPoint->tp_clear(o); } else __Pyx_call_next_tp_clear(o, __pyx_tp_clear_13_rnaseq_utils_EndPoint);
  tmp = ((PyObject*)p->span);
  p->span = Py_None; Py_INCREF(Py_None);
  Py_XDECREF(tmp);
  return 0;
}

static PyObject *__pyx_getprop_13_rnaseq_utils_8EndPoint_extend(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_8EndPoint_6extend_1__get__(o);
}

static int __pyx_setprop_13_rnaseq_utils_8EndPoint_extend(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
  if (v) {
    return __pyx_pw_13_rnaseq_utils_8EndPoint_6extend_3__set__(o, v);
  }
  else {
    PyErr_SetString(PyExc_NotImplementedError, "__del__");
    return -1;
  }
}

static PyObject *__pyx_getprop_13_rnaseq_utils_8EndPoint_span(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_8EndPoint_4span_1__get__(o);
}

static int __pyx_setprop_13_rnaseq_utils_8EndPoint_span(PyObject *o, PyObject *v, CYTHON_UNUSED void *x) {
  if (v) {
    return __pyx_pw_13_rnaseq_utils_8EndPoint_4span_3__set__(o, v);
  }
  else {
    return __pyx_pw_13_rnaseq_utils_8EndPoint_4span_5__del__(o);
  }
}

static PyMethodDef __pyx_methods_13_rnaseq_utils_EndPoint[] = {
  {"merge", (PyCFunction)__pyx_pw_13_rnaseq_utils_8EndPoint_3merge, METH_O, __pyx_doc_13_rnaseq_utils_8EndPoint_2merge},
  {"__reduce_cython__", (PyCFunction)__pyx_pw_13_rnaseq_utils_8EndPoint_5__reduce_cython__, METH_NOARGS, 0},
  {"__setstate_cython__", (PyCFunction)__pyx_pw_13_rnaseq_utils_8EndPoint_7__setstate_cython__, METH_O, 0},
  {0, 0, 0, 0}
};

static struct PyGetSetDef __pyx_getsets_13_rnaseq_utils_EndPoint[] = {
  {(char *)"extend", __pyx_getprop_13_rnaseq_utils_8EndPoint_extend, __pyx_setprop_13_rnaseq_utils_8EndPoint_extend, (char *)0, 0},
  {(char *)"span", __pyx_getprop_13_rnaseq_utils_8EndPoint_span, __pyx_setprop_13_rnaseq_utils_8EndPoint_span, (char *)0, 0},
  {0, 0, 0, 0, 0}
};

static PyTypeObject __pyx_type_13_rnaseq_utils_EndPoint = {
  PyVarObject_HEAD_INIT(0, 0)
  "_rnaseq_utils.EndPoint", /*tp_name*/
  sizeof(struct __pyx_obj_13_rnaseq_utils_EndPoint), /*tp_basicsize*/
  0, /*tp_itemsize*/
  __pyx_tp_dealloc_13_rnaseq_utils_EndPoint, /*tp_dealloc*/
  0, /*tp_print*/
  0, /*tp_getattr*/
  0, /*tp_setattr*/
  #if PY_MAJOR_VERSION < 3
  0, /*tp_compare*/
  #endif
  #if PY_MAJOR_VERSION >= 3
  0, /*tp_as_async*/
  #endif
  #if CYTHON_COMPILING_IN_PYPY
  __pyx_pw_13_rnaseq_utils_11BranchPoint_5__repr__, /*tp_repr*/
  #else
  0, /*tp_repr*/
  #endif
  0, /*tp_as_number*/
  0, /*tp_as_sequence*/
  0, /*tp_as_mapping*/
  0, /*tp_hash*/
  0, /*tp_call*/
  0, /*tp_str*/
  0, /*tp_getattro*/
  0, /*tp_setattro*/
  0, /*tp_as_buffer*/
  Py_TPFLAGS_DEFAULT|Py_TPFLAGS_HAVE_VERSION_TAG|Py_TPFLAGS_CHECKTYPES|Py_TPFLAGS_HAVE_NEWBUFFER|Py_TPFLAGS_BASETYPE|Py_TPFLAGS_HAVE_GC, /*tp_flags*/
  "Represents a transcript termination site", /*tp_doc*/
  __pyx_tp_traverse_13_rnaseq_utils_EndPoint, /*tp_traverse*/
  __pyx_tp_clear_13_rnaseq_utils_EndPoint, /*tp_clear*/
  0, /*tp_richcompare*/
  0, /*tp_weaklistoffset*/
  0, /*tp_iter*/
  0, /*tp_iternext*/
  __pyx_methods_13_rnaseq_utils_EndPoint, /*tp_methods*/
  0, /*tp_members*/
  __pyx_getsets_13_rnaseq_utils_EndPoint, /*tp_getset*/
  0, /*tp_base*/
  0, /*tp_dict*/
  0, /*tp_descr_get*/
  0, /*tp_descr_set*/
  0, /*tp_dictoffset*/
  __pyx_pw_13_rnaseq_utils_8EndPoint_1__init__, /*tp_init*/
  0, /*tp_alloc*/
  __pyx_tp_new_13_rnaseq_utils_EndPoint, /*tp_new*/
  0, /*tp_free*/
  0, /*tp_is_gc*/
  0, /*tp_bases*/
  0, /*tp_mro*/
  0, /*tp_cache*/
  0, /*tp_subclasses*/
  0, /*tp_weaklist*/
  0, /*tp_del*/
  0, /*tp_version_tag*/
  #if PY_VERSION_HEX >= 0x030400a1
  0, /*tp_finalize*/
  #endif
  #if PY_VERSION_HEX >= 0x030800b1
  0, /*tp_vectorcall*/
  #endif
};
static struct __pyx_vtabstruct_13_rnaseq_utils_DonorPoint __pyx_vtable_13_rnaseq_utils_DonorPoint;

static PyObject *__pyx_tp_new_13_rnaseq_utils_DonorPoint(PyTypeObject *t, PyObject *a, PyObject *k) {
  struct __pyx_obj_13_rnaseq_utils_DonorPoint *p;
  PyObject *o = __pyx_tp_new_13_rnaseq_utils_BranchPoint(t, a, k);
  if (unlikely(!o)) return 0;
  p = ((struct __pyx_obj_13_rnaseq_utils_DonorPoint *)o);
  p->__pyx_base.__pyx_vtab = (struct __pyx_vtabstruct_13_rnaseq_utils_BranchPoint*)__pyx_vtabptr_13_rnaseq_utils_DonorPoint;
  return o;
}

static PyMethodDef __pyx_methods_13_rnaseq_utils_DonorPoint[] = {
  {"__reduce_cython__", (PyCFunction)__pyx_pw_13_rnaseq_utils_10DonorPoint_3__reduce_cython__, METH_NOARGS, 0},
  {"__setstate_cython__", (PyCFunction)__pyx_pw_13_rnaseq_utils_10DonorPoint_5__setstate_cython__, METH_O, 0},
  {0, 0, 0, 0}
};

static PyTypeObject __pyx_type_13_rnaseq_utils_DonorPoint = {
  PyVarObject_HEAD_INIT(0, 0)
  "_rnaseq_utils.DonorPoint", /*tp_name*/
  sizeof(struct __pyx_obj_13_rnaseq_utils_DonorPoint), /*tp_basicsize*/
  0, /*tp_itemsize*/
  __pyx_tp_dealloc_13_rnaseq_utils_BranchPoint, /*tp_dealloc*/
  0, /*tp_print*/
  0, /*tp_getattr*/
  0, /*tp_setattr*/
  #if PY_MAJOR_VERSION < 3
  0, /*tp_compare*/
  #endif
  #if PY_MAJOR_VERSION >= 3
  0, /*tp_as_async*/
  #endif
  #if CYTHON_COMPILING_IN_PYPY
  __pyx_pw_13_rnaseq_utils_11BranchPoint_5__repr__, /*tp_repr*/
  #else
  0, /*tp_repr*/
  #endif
  0, /*tp_as_number*/
  0, /*tp_as_sequence*/
  0, /*tp_as_mapping*/
  0, /*tp_hash*/
  0, /*tp_call*/
  0, /*tp_str*/
  0, /*tp_getattro*/
  0, /*tp_setattro*/
  0, /*tp_as_buffer*/
  Py_TPFLAGS_DEFAULT|Py_TPFLAGS_HAVE_VERSION_TAG|Py_TPFLAGS_CHECKTYPES|Py_TPFLAGS_HAVE_NEWBUFFER|Py_TPFLAGS_BASETYPE, /*tp_flags*/
  "Represents a transcript start site", /*tp_doc*/
  0, /*tp_traverse*/
  0, /*tp_clear*/
  0, /*tp_richcompare*/
  0, /*tp_weaklistoffset*/
  0, /*tp_iter*/
  0, /*tp_iternext*/
  __pyx_methods_13_rnaseq_utils_DonorPoint, /*tp_methods*/
  0, /*tp_members*/
  0, /*tp_getset*/
  0, /*tp_base*/
  0, /*tp_dict*/
  0, /*tp_descr_get*/
  0, /*tp_descr_set*/
  0, /*tp_dictoffset*/
  __pyx_pw_13_rnaseq_utils_10DonorPoint_1__init__, /*tp_init*/
  0, /*tp_alloc*/
  __pyx_tp_new_13_rnaseq_utils_DonorPoint, /*tp_new*/
  0, /*tp_free*/
  0, /*tp_is_gc*/
  0, /*tp_bases*/
  0, /*tp_mro*/
  0, /*tp_cache*/
  0, /*tp_subclasses*/
  0, /*tp_weaklist*/
  0, /*tp_del*/
  0, /*tp_version_tag*/
  #if PY_VERSION_HEX >= 0x030400a1
  0, /*tp_finalize*/
  #endif
  #if PY_VERSION_HEX >= 0x030800b1
  0, /*tp_vectorcall*/
  #endif
};
static struct __pyx_vtabstruct_13_rnaseq_utils_AcceptorPoint __pyx_vtable_13_rnaseq_utils_AcceptorPoint;

static PyObject *__pyx_tp_new_13_rnaseq_utils_AcceptorPoint(PyTypeObject *t, PyObject *a, PyObject *k) {
  struct __pyx_obj_13_rnaseq_utils_AcceptorPoint *p;
  PyObject *o = __pyx_tp_new_13_rnaseq_utils_BranchPoint(t, a, k);
  if (unlikely(!o)) return 0;
  p = ((struct __pyx_obj_13_rnaseq_utils_AcceptorPoint *)o);
  p->__pyx_base.__pyx_vtab = (struct __pyx_vtabstruct_13_rnaseq_utils_BranchPoint*)__pyx_vtabptr_13_rnaseq_utils_AcceptorPoint;
  return o;
}

static PyMethodDef __pyx_methods_13_rnaseq_utils_AcceptorPoint[] = {
  {"__reduce_cython__", (PyCFunction)__pyx_pw_13_rnaseq_utils_13AcceptorPoint_3__reduce_cython__, METH_NOARGS, 0},
  {"__setstate_cython__", (PyCFunction)__pyx_pw_13_rnaseq_utils_13AcceptorPoint_5__setstate_cython__, METH_O, 0},
  {0, 0, 0, 0}
};

static PyTypeObject __pyx_type_13_rnaseq_utils_AcceptorPoint = {
  PyVarObject_HEAD_INIT(0, 0)
  "_rnaseq_utils.AcceptorPoint", /*tp_name*/
  sizeof(struct __pyx_obj_13_rnaseq_utils_AcceptorPoint), /*tp_basicsize*/
  0, /*tp_itemsize*/
  __pyx_tp_dealloc_13_rnaseq_utils_BranchPoint, /*tp_dealloc*/
  0, /*tp_print*/
  0, /*tp_getattr*/
  0, /*tp_setattr*/
  #if PY_MAJOR_VERSION < 3
  0, /*tp_compare*/
  #endif
  #if PY_MAJOR_VERSION >= 3
  0, /*tp_as_async*/
  #endif
  #if CYTHON_COMPILING_IN_PYPY
  __pyx_pw_13_rnaseq_utils_11BranchPoint_5__repr__, /*tp_repr*/
  #else
  0, /*tp_repr*/
  #endif
  0, /*tp_as_number*/
  0, /*tp_as_sequence*/
  0, /*tp_as_mapping*/
  0, /*tp_hash*/
  0, /*tp_call*/
  0, /*tp_str*/
  0, /*tp_getattro*/
  0, /*tp_setattro*/
  0, /*tp_as_buffer*/
  Py_TPFLAGS_DEFAULT|Py_TPFLAGS_HAVE_VERSION_TAG|Py_TPFLAGS_CHECKTYPES|Py_TPFLAGS_HAVE_NEWBUFFER|Py_TPFLAGS_BASETYPE, /*tp_flags*/
  "Represents a transcript start site", /*tp_doc*/
  0, /*tp_traverse*/
  0, /*tp_clear*/
  0, /*tp_richcompare*/
  0, /*tp_weaklistoffset*/
  0, /*tp_iter*/
  0, /*tp_iternext*/
  __pyx_methods_13_rnaseq_utils_AcceptorPoint, /*tp_methods*/
  0, /*tp_members*/
  0, /*tp_getset*/
  0, /*tp_base*/
  0, /*tp_dict*/
  0, /*tp_descr_get*/
  0, /*tp_descr_set*/
  0, /*tp_dictoffset*/
  __pyx_pw_13_rnaseq_utils_13AcceptorPoint_1__init__, /*tp_init*/
  0, /*tp_alloc*/
  __pyx_tp_new_13_rnaseq_utils_AcceptorPoint, /*tp_new*/
  0, /*tp_free*/
  0, /*tp_is_gc*/
  0, /*tp_bases*/
  0, /*tp_mro*/
  0, /*tp_cache*/
  0, /*tp_subclasses*/
  0, /*tp_weaklist*/
  0, /*tp_del*/
  0, /*tp_version_tag*/
  #if PY_VERSION_HEX >= 0x030400a1
  0, /*tp_finalize*/
  #endif
  #if PY_VERSION_HEX >= 0x030800b1
  0, /*tp_vectorcall*/
  #endif
};
static struct __pyx_vtabstruct_13_rnaseq_utils_OrderedArray __pyx_vtable_13_rnaseq_utils_OrderedArray;

static PyObject *__pyx_tp_new_13_rnaseq_utils_OrderedArray(PyTypeObject *t, CYTHON_UNUSED PyObject *a, CYTHON_UNUSED PyObject *k) {
  struct __pyx_obj_13_rnaseq_utils_OrderedArray *p;
  PyObject *o;
  if (likely((t->tp_flags & Py_TPFLAGS_IS_ABSTRACT) == 0)) {
    o = (*t->tp_alloc)(t, 0);
  } else {
    o = (PyObject *) PyBaseObject_Type.tp_new(t, __pyx_empty_tuple, 0);
  }
  if (unlikely(!o)) return 0;
  p = ((struct __pyx_obj_13_rnaseq_utils_OrderedArray *)o);
  p->__pyx_vtab = __pyx_vtabptr_13_rnaseq_utils_OrderedArray;
  p->ordered_array = ((PyObject*)Py_None); Py_INCREF(Py_None);
  return o;
}

static void __pyx_tp_dealloc_13_rnaseq_utils_OrderedArray(PyObject *o) {
  struct __pyx_obj_13_rnaseq_utils_OrderedArray *p = (struct __pyx_obj_13_rnaseq_utils_OrderedArray *)o;
  #if CYTHON_USE_TP_FINALIZE
  if (unlikely(PyType_HasFeature(Py_TYPE(o), Py_TPFLAGS_HAVE_FINALIZE) && Py_TYPE(o)->tp_finalize) && !_PyGC_FINALIZED(o)) {
    if (PyObject_CallFinalizerFromDealloc(o)) return;
  }
  #endif
  PyObject_GC_UnTrack(o);
  Py_CLEAR(p->ordered_array);
  (*Py_TYPE(o)->tp_free)(o);
}

static int __pyx_tp_traverse_13_rnaseq_utils_OrderedArray(PyObject *o, visitproc v, void *a) {
  int e;
  struct __pyx_obj_13_rnaseq_utils_OrderedArray *p = (struct __pyx_obj_13_rnaseq_utils_OrderedArray *)o;
  if (p->ordered_array) {
    e = (*v)(p->ordered_array, a); if (e) return e;
  }
  return 0;
}

static int __pyx_tp_clear_13_rnaseq_utils_OrderedArray(PyObject *o) {
  PyObject* tmp;
  struct __pyx_obj_13_rnaseq_utils_OrderedArray *p = (struct __pyx_obj_13_rnaseq_utils_OrderedArray *)o;
  tmp = ((PyObject*)p->ordered_array);
  p->ordered_array = ((PyObject*)Py_None); Py_INCREF(Py_None);
  Py_XDECREF(tmp);
  return 0;
}

static PyObject *__pyx_getprop_13_rnaseq_utils_12OrderedArray_n(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_12OrderedArray_1n_1__get__(o);
}

static PyObject *__pyx_getprop_13_rnaseq_utils_12OrderedArray_ordered_array(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_13_rnaseq_utils_12OrderedArray_13ordered_array_1__get__(o);
}

static PyMethodDef __pyx_methods_13_rnaseq_utils_OrderedArray[] = {
  {"ordered_index", (PyCFunction)(void*)(PyCFunctionWithKeywords)__pyx_pw_13_rnaseq_utils_12OrderedArray_5ordered_index, METH_VARARGS|METH_KEYWORDS, 0},
  {"ordered_values", (PyCFunction)(void*)(PyCFunctionWithKeywords)__pyx_pw_13_rnaseq_utils_12OrderedArray_7ordered_values, METH_VARARGS|METH_KEYWORDS, 0},
  {"add", (PyCFunction)(void*)(PyCFunctionWithKeywords)__pyx_pw_13_rnaseq_utils_12OrderedArray_15add, METH_VARARGS|METH_KEYWORDS, __pyx_doc_13_rnaseq_utils_12OrderedArray_14add},
  {"delete", (PyCFunction)__pyx_pw_13_rnaseq_utils_12OrderedArray_17delete, METH_O, __pyx_doc_13_rnaseq_utils_12OrderedArray_16delete},
  {"add_list", (PyCFunction)__pyx_pw_13_rnaseq_utils_12OrderedArray_19add_list, METH_O, 0},
  {"probe", (PyCFunction)(void*)(PyCFunctionWithKeywords)__pyx_pw_13_rnaseq_utils_12OrderedArray_21probe, METH_VARARGS|METH_KEYWORDS, __pyx_doc_13_rnaseq_utils_12OrderedArray_20probe},
  {"__reduce_cython__", (PyCFunction)__pyx_pw_13_rnaseq_utils_12OrderedArray_23__reduce_cython__, METH_NOARGS, 0},
  {"__setstate_cython__", (PyCFunction)__pyx_pw_13_rnaseq_utils_12OrderedArray_25__setstate_cython__, METH_O, 0},
  {0, 0, 0, 0}
};

static struct PyGetSetDef __pyx_getsets_13_rnaseq_utils_OrderedArray[] = {
  {(char *)"n", __pyx_getprop_13_rnaseq_utils_12OrderedArray_n, 0, (char *)0, 0},
  {(char *)"ordered_array", __pyx_getprop_13_rnaseq_utils_12OrderedArray_ordered_array, 0, (char *)0, 0},
  {0, 0, 0, 0, 0}
};

static PyNumberMethods __pyx_tp_as_number_OrderedArray = {
  __pyx_pw_13_rnaseq_utils_12OrderedArray_13__add__, /*nb_add*/
  0, /*nb_subtract*/
  0, /*nb_multiply*/
  #if PY_MAJOR_VERSION < 3 || (CYTHON_COMPILING_IN_PYPY && PY_VERSION_HEX < 0x03050000)
  0, /*nb_divide*/
  #endif
  0, /*nb_remainder*/
  0, /*nb_divmod*/
  0, /*nb_power*/
  0, /*nb_negative*/
  0, /*nb_positive*/
  0, /*nb_absolute*/
  0, /*nb_nonzero*/
  0, /*nb_invert*/
  0, /*nb_lshift*/
  0, /*nb_rshift*/
  0, /*nb_and*/
  0, /*nb_xor*/
  0, /*nb_or*/
  #if PY_MAJOR_VERSION < 3 || (CYTHON_COMPILING_IN_PYPY && PY_VERSION_HEX < 0x03050000)
  0, /*nb_coerce*/
  #endif
  0, /*nb_int*/
  #if PY_MAJOR_VERSION < 3
  0, /*nb_long*/
  #else
  0, /*reserved*/
  #endif
  0, /*nb_float*/
  #if PY_MAJOR_VERSION < 3 || (CYTHON_COMPILING_IN_PYPY && PY_VERSION_HEX < 0x03050000)
  0, /*nb_oct*/
  #endif
  #if PY_MAJOR_VERSION < 3 || (CYTHON_COMPILING_IN_PYPY && PY_VERSION_HEX < 0x03050000)
  0, /*nb_hex*/
  #endif
  0, /*nb_inplace_add*/
  0, /*nb_inplace_subtract*/
  0, /*nb_inplace_multiply*/
  #if PY_MAJOR_VERSION < 3 || (CYTHON_COMPILING_IN_PYPY && PY_VERSION_HEX < 0x03050000)
  0, /*nb_inplace_divide*/
  #endif
  0, /*nb_inplace_remainder*/
  0, /*nb_inplace_power*/
  0, /*nb_inplace_lshift*/
  0, /*nb_inplace_rshift*/
  0, /*nb_inplace_and*/
  0, /*nb_inplace_xor*/
  0, /*nb_inplace_or*/
  0, /*nb_floor_divide*/
  0, /*nb_true_divide*/
  0, /*nb_inplace_floor_divide*/
  0, /*nb_inplace_true_divide*/
  0, /*nb_index*/
  #if PY_VERSION_HEX >= 0x03050000
  0, /*nb_matrix_multiply*/
  #endif
  #if PY_VERSION_HEX >= 0x03050000
  0, /*nb_inplace_matrix_multiply*/
  #endif
};

static PySequenceMethods __pyx_tp_as_sequence_OrderedArray = {
  __pyx_pw_13_rnaseq_utils_12OrderedArray_11__len__, /*sq_length*/
  0, /*sq_concat*/
  0, /*sq_repeat*/
  0, /*sq_item*/
  0, /*sq_slice*/
  0, /*sq_ass_item*/
  0, /*sq_ass_slice*/
  0, /*sq_contains*/
  0, /*sq_inplace_concat*/
  0, /*sq_inplace_repeat*/
};

static PyMappingMethods __pyx_tp_as_mapping_OrderedArray = {
  __pyx_pw_13_rnaseq_utils_12OrderedArray_11__len__, /*mp_length*/
  0, /*mp_subscript*/
  0, /*mp_ass_subscript*/
};

static PyTypeObject __pyx_type_13_rnaseq_utils_OrderedArray = {
  PyVarObject_HEAD_INIT(0, 0)
  "_rnaseq_utils.OrderedArray", /*tp_name*/
  sizeof(struct __pyx_obj_13_rnaseq_utils_OrderedArray), /*tp_basicsize*/
  0, /*tp_itemsize*/
  __pyx_tp_dealloc_13_rnaseq_utils_OrderedArray, /*tp_dealloc*/
  0, /*tp_print*/
  0, /*tp_getattr*/
  0, /*tp_setattr*/
  #if PY_MAJOR_VERSION < 3
  0, /*tp_compare*/
  #endif
  #if PY_MAJOR_VERSION >= 3
  0, /*tp_as_async*/
  #endif
  __pyx_pw_13_rnaseq_utils_12OrderedArray_3__repr__, /*tp_repr*/
  &__pyx_tp_as_number_OrderedArray, /*tp_as_number*/
  &__pyx_tp_as_sequence_OrderedArray, /*tp_as_sequence*/
  &__pyx_tp_as_mapping_OrderedArray, /*tp_as_mapping*/
  0, /*tp_hash*/
  0, /*tp_call*/
  0, /*tp_str*/
  0, /*tp_getattro*/
  0, /*tp_setattro*/
  0, /*tp_as_buffer*/
  Py_TPFLAGS_DEFAULT|Py_TPFLAGS_HAVE_VERSION_TAG|Py_TPFLAGS_CHECKTYPES|Py_TPFLAGS_HAVE_NEWBUFFER|Py_TPFLAGS_BASETYPE|Py_TPFLAGS_HAVE_GC, /*tp_flags*/
  "Maintains an array in sort order and a lookup dict for the location of each\n    item that was added.", /*tp_doc*/
  __pyx_tp_traverse_13_rnaseq_utils_OrderedArray, /*tp_traverse*/
  __pyx_tp_clear_13_rnaseq_utils_OrderedArray, /*tp_clear*/
  0, /*tp_richcompare*/
  0, /*tp_weaklistoffset*/
  __pyx_pw_13_rnaseq_utils_12OrderedArray_9__iter__, /*tp_iter*/
  0, /*tp_iternext*/
  __pyx_methods_13_rnaseq_utils_OrderedArray, /*tp_methods*/
  0, /*tp_members*/
  __pyx_getsets_13_rnaseq_utils_OrderedArray, /*tp_getset*/
  0, /*tp_base*/
  0, /*tp_dict*/
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  __pyx_pw_13_rnaseq_utils_12OrderedArray_1__init__, /*tp_init*/
  0, /*tp_alloc*/
  __pyx_tp_new_13_rnaseq_utils_OrderedArray, /*tp_new*/
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static struct __pyx_obj_13_rnaseq_utils___pyx_scope_struct__generate_loci *__pyx_freelist_13_rnaseq_utils___pyx_scope_struct__generate_loci[8];
static int __pyx_freecount_13_rnaseq_utils___pyx_scope_struct__generate_loci = 0;

static PyObject *__pyx_tp_new_13_rnaseq_utils___pyx_scope_struct__generate_loci(PyTypeObject *t, CYTHON_UNUSED PyObject *a, CYTHON_UNUSED PyObject *k) {
  PyObject *o;
  if (CYTHON_COMPILING_IN_CPYTHON && likely((__pyx_freecount_13_rnaseq_utils___pyx_scope_struct__generate_loci > 0) & (t->tp_basicsize == sizeof(struct __pyx_obj_13_rnaseq_utils___pyx_scope_struct__generate_loci)))) {
    o = (PyObject*)__pyx_freelist_13_rnaseq_utils___pyx_scope_struct__generate_loci[--__pyx_freecount_13_rnaseq_utils___pyx_scope_struct__generate_loci];
    memset(o, 0, sizeof(struct __pyx_obj_13_rnaseq_utils___pyx_scope_struct__generate_loci));
    (void) PyObject_INIT(o, t);
    PyObject_GC_Track(o);
  } else {
    o = (*t->tp_alloc)(t, 0);
    if (unlikely(!o)) return 0;
  }
  return o;
}

static void __pyx_tp_dealloc_13_rnaseq_utils___pyx_scope_struct__generate_loci(PyObject *o) {
  struct __pyx_obj_13_rnaseq_utils___pyx_scope_struct__generate_loci *p = (struct __pyx_obj_13_rnaseq_utils___pyx_scope_struct__generate_loci *)o;
  PyObject_GC_UnTrack(o);
  Py_CLEAR(p->__pyx_v_chrom);
  Py_CLEAR(p->__pyx_v_chrom_annotation_list);
  Py_CLEAR(p->__pyx_v_current_chunk);
  Py_CLEAR(p->__pyx_v_item);
  Py_CLEAR(p->__pyx_v_k);
  Py_CLEAR(p->__pyx_v_self);
  Py_CLEAR(p->__pyx_t_0);
  if (CYTHON_COMPILING_IN_CPYTHON && ((__pyx_freecount_13_rnaseq_utils___pyx_scope_struct__generate_loci < 8) & (Py_TYPE(o)->tp_basicsize == sizeof(struct __pyx_obj_13_rnaseq_utils___pyx_scope_struct__generate_loci)))) {
    __pyx_freelist_13_rnaseq_utils___pyx_scope_struct__generate_loci[__pyx_freecount_13_rnaseq_utils___pyx_scope_struct__generate_loci++] = ((struct __pyx_obj_13_rnaseq_utils___pyx_scope_struct__generate_loci *)o);
  } else {
    (*Py_TYPE(o)->tp_free)(o);
  }
}

static int __pyx_tp_traverse_13_rnaseq_utils___pyx_scope_struct__generate_loci(PyObject *o, visitproc v, void *a) {
  int e;
  struct __pyx_obj_13_rnaseq_utils___pyx_scope_struct__generate_loci *p = (struct __pyx_obj_13_rnaseq_utils___pyx_scope_struct__generate_loci *)o;
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  }
  if (p->__pyx_v_current_chunk) {
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  }
  return 0;
}

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static struct __pyx_obj_13_rnaseq_utils___pyx_scope_struct_1_array_to_blocks *__pyx_freelist_13_rnaseq_utils___pyx_scope_struct_1_array_to_blocks[8];
static int __pyx_freecount_13_rnaseq_utils___pyx_scope_struct_1_array_to_blocks = 0;

static PyObject *__pyx_tp_new_13_rnaseq_utils___pyx_scope_struct_1_array_to_blocks(PyTypeObject *t, CYTHON_UNUSED PyObject *a, CYTHON_UNUSED PyObject *k) {
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    (void) PyObject_INIT(o, t);
    PyObject_GC_Track(o);
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static void __pyx_tp_dealloc_13_rnaseq_utils___pyx_scope_struct_1_array_to_blocks(PyObject *o) {
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  Py_CLEAR(p->__pyx_v_arr);
  Py_CLEAR(p->__pyx_v_clean_array);
  Py_CLEAR(p->__pyx_t_0);
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    __pyx_freelist_13_rnaseq_utils___pyx_scope_struct_1_array_to_blocks[__pyx_freecount_13_rnaseq_utils___pyx_scope_struct_1_array_to_blocks++] = ((struct __pyx_obj_13_rnaseq_utils___pyx_scope_struct_1_array_to_blocks *)o);
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static int __pyx_tp_traverse_13_rnaseq_utils___pyx_scope_struct_1_array_to_blocks(PyObject *o, visitproc v, void *a) {
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static struct __pyx_obj_13_rnaseq_utils___pyx_scope_struct_2_split_chunk *__pyx_freelist_13_rnaseq_utils___pyx_scope_struct_2_split_chunk[8];
static int __pyx_freecount_13_rnaseq_utils___pyx_scope_struct_2_split_chunk = 0;

static PyObject *__pyx_tp_new_13_rnaseq_utils___pyx_scope_struct_2_split_chunk(PyTypeObject *t, CYTHON_UNUSED PyObject *a, CYTHON_UNUSED PyObject *k) {
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  if (CYTHON_COMPILING_IN_CPYTHON && likely((__pyx_freecount_13_rnaseq_utils___pyx_scope_struct_2_split_chunk > 0) & (t->tp_basicsize == sizeof(struct __pyx_obj_13_rnaseq_utils___pyx_scope_struct_2_split_chunk)))) {
    o = (PyObject*)__pyx_freelist_13_rnaseq_utils___pyx_scope_struct_2_split_chunk[--__pyx_freecount_13_rnaseq_utils___pyx_scope_struct_2_split_chunk];
    memset(o, 0, sizeof(struct __pyx_obj_13_rnaseq_utils___pyx_scope_struct_2_split_chunk));
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    o = (*t->tp_alloc)(t, 0);
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  p->__pyx_v_COV.memview = NULL;
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}

static void __pyx_tp_dealloc_13_rnaseq_utils___pyx_scope_struct_2_split_chunk(PyObject *o) {
  struct __pyx_obj_13_rnaseq_utils___pyx_scope_struct_2_split_chunk *p = (struct __pyx_obj_13_rnaseq_utils___pyx_scope_struct_2_split_chunk *)o;
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  Py_CLEAR(p->__pyx_v_coverage);
  Py_CLEAR(p->__pyx_v_is_gap);
  Py_CLEAR(p->__pyx_v_read);
  Py_CLEAR(p->__pyx_v_reads);
  __PYX_XDEC_MEMVIEW(&p->__pyx_v_COV, 1);
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  }
}

static int __pyx_tp_traverse_13_rnaseq_utils___pyx_scope_struct_2_split_chunk(PyObject *o, visitproc v, void *a) {
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static PyTypeObject __pyx_type_13_rnaseq_utils___pyx_scope_struct_2_split_chunk = {
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  __pyx_tp_dealloc_13_rnaseq_utils___pyx_scope_struct_2_split_chunk, /*tp_dealloc*/
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static struct __pyx_obj_13_rnaseq_utils___pyx_scope_struct_3_parse_MD_string *__pyx_freelist_13_rnaseq_utils___pyx_scope_struct_3_parse_MD_string[8];
static int __pyx_freecount_13_rnaseq_utils___pyx_scope_struct_3_parse_MD_string = 0;

static PyObject *__pyx_tp_new_13_rnaseq_utils___pyx_scope_struct_3_parse_MD_string(PyTypeObject *t, CYTHON_UNUSED PyObject *a, CYTHON_UNUSED PyObject *k) {
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    (void) PyObject_INIT(o, t);
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  return o;
}

static void __pyx_tp_dealloc_13_rnaseq_utils___pyx_scope_struct_3_parse_MD_string(PyObject *o) {
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  Py_CLEAR(p->__pyx_v_c);
  Py_CLEAR(p->__pyx_v_current);
  Py_CLEAR(p->__pyx_v_mdstring);
  Py_CLEAR(p->__pyx_t_0);
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    __pyx_freelist_13_rnaseq_utils___pyx_scope_struct_3_parse_MD_string[__pyx_freecount_13_rnaseq_utils___pyx_scope_struct_3_parse_MD_string++] = ((struct __pyx_obj_13_rnaseq_utils___pyx_scope_struct_3_parse_MD_string *)o);
  } else {
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}

static PyTypeObject __pyx_type_13_rnaseq_utils___pyx_scope_struct_3_parse_MD_string = {
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  0, /*tp_cache*/
  0, /*tp_subclasses*/
  0, /*tp_weaklist*/
  0, /*tp_del*/
  0, /*tp_version_tag*/
  #if PY_VERSION_HEX >= 0x030400a1
  0, /*tp_finalize*/
  #endif
  #if PY_VERSION_HEX >= 0x030800b1
  0, /*tp_vectorcall*/
  #endif
};

static struct __pyx_obj_13_rnaseq_utils___pyx_scope_struct_4_read_generator *__pyx_freelist_13_rnaseq_utils___pyx_scope_struct_4_read_generator[8];
static int __pyx_freecount_13_rnaseq_utils___pyx_scope_struct_4_read_generator = 0;

static PyObject *__pyx_tp_new_13_rnaseq_utils___pyx_scope_struct_4_read_generator(PyTypeObject *t, CYTHON_UNUSED PyObject *a, CYTHON_UNUSED PyObject *k) {
  PyObject *o;
  if (CYTHON_COMPILING_IN_CPYTHON && likely((__pyx_freecount_13_rnaseq_utils___pyx_scope_struct_4_read_generator > 0) & (t->tp_basicsize == sizeof(struct __pyx_obj_13_rnaseq_utils___pyx_scope_struct_4_read_generator)))) {
    o = (PyObject*)__pyx_freelist_13_rnaseq_utils___pyx_scope_struct_4_read_generator[--__pyx_freecount_13_rnaseq_utils___pyx_scope_struct_4_read_generator];
    memset(o, 0, sizeof(struct __pyx_obj_13_rnaseq_utils___pyx_scope_struct_4_read_generator));
    (void) PyObject_INIT(o, t);
    PyObject_GC_Track(o);
  } else {
    o = (*t->tp_alloc)(t, 0);
    if (unlikely(!o)) return 0;
  }
  return o;
}

static void __pyx_tp_dealloc_13_rnaseq_utils___pyx_scope_struct_4_read_generator(PyObject *o) {
  struct __pyx_obj_13_rnaseq_utils___pyx_scope_struct_4_read_generator *p = (struct __pyx_obj_13_rnaseq_utils___pyx_scope_struct_4_read_generator *)o;
  PyObject_GC_UnTrack(o);
  Py_CLEAR(p->__pyx_v_add_read);
  Py_CLEAR(p->__pyx_v_dataset);
  Py_CLEAR(p->__pyx_v_file_type);
  Py_CLEAR(p->__pyx_v_fileconn);
  Py_CLEAR(p->__pyx_v_header_line);
  Py_CLEAR(p->__pyx_v_last_read);
  Py_CLEAR(p->__pyx_v_line);
  Py_CLEAR(p->__pyx_t_0);
  if (CYTHON_COMPILING_IN_CPYTHON && ((__pyx_freecount_13_rnaseq_utils___pyx_scope_struct_4_read_generator < 8) & (Py_TYPE(o)->tp_basicsize == sizeof(struct __pyx_obj_13_rnaseq_utils___pyx_scope_struct_4_read_generator)))) {
    __pyx_freelist_13_rnaseq_utils___pyx_scope_struct_4_read_generator[__pyx_freecount_13_rnaseq_utils___pyx_scope_struct_4_read_generator++] = ((struct __pyx_obj_13_rnaseq_utils___pyx_scope_struct_4_read_generator *)o);
  } else {
    (*Py_TYPE(o)->tp_free)(o);
  }
}

static int __pyx_tp_traverse_13_rnaseq_utils___pyx_scope_struct_4_read_generator(PyObject *o, visitproc v, void *a) {
  int e;
  struct __pyx_obj_13_rnaseq_utils___pyx_scope_struct_4_read_generator *p = (struct __pyx_obj_13_rnaseq_utils___pyx_scope_struct_4_read_generator *)o;
  if (p->__pyx_v_add_read) {
    e = (*v)(p->__pyx_v_add_read, a); if (e) return e;
  }
  if (p->__pyx_v_dataset) {
    e = (*v)(((PyObject *)p->__pyx_v_dataset), a); if (e) return e;
  }
  if (p->__pyx_v_fileconn) {
    e = (*v)(p->__pyx_v_fileconn, a); if (e) return e;
  }
  if (p->__pyx_v_header_line) {
    e = (*v)(p->__pyx_v_header_line, a); if (e) return e;
  }
  if (p->__pyx_v_last_read) {
    e = (*v)(((PyObject *)p->__pyx_v_last_read), a); if (e) return e;
  }
  if (p->__pyx_v_line) {
    e = (*v)(p->__pyx_v_line, a); if (e) return e;
  }
  if (p->__pyx_t_0) {
    e = (*v)(p->__pyx_t_0, a); if (e) return e;
  }
  return 0;
}

static PyTypeObject __pyx_type_13_rnaseq_utils___pyx_scope_struct_4_read_generator = {
  PyVarObject_HEAD_INIT(0, 0)
  "_rnaseq_utils.__pyx_scope_struct_4_read_generator", /*tp_name*/
  sizeof(struct __pyx_obj_13_rnaseq_utils___pyx_scope_struct_4_read_generator), /*tp_basicsize*/
  0, /*tp_itemsize*/
  __pyx_tp_dealloc_13_rnaseq_utils___pyx_scope_struct_4_read_generator, /*tp_dealloc*/
  0, /*tp_print*/
  0, /*tp_getattr*/
  0, /*tp_setattr*/
  #if PY_MAJOR_VERSION < 3
  0, /*tp_compare*/
  #endif
  #if PY_MAJOR_VERSION >= 3
  0, /*tp_as_async*/
  #endif
  0, /*tp_repr*/
  0, /*tp_as_number*/
  0, /*tp_as_sequence*/
  0, /*tp_as_mapping*/
  0, /*tp_hash*/
  0, /*tp_call*/
  0, /*tp_str*/
  0, /*tp_getattro*/
  0, /*tp_setattro*/
  0, /*tp_as_buffer*/
  Py_TPFLAGS_DEFAULT|Py_TPFLAGS_HAVE_VERSION_TAG|Py_TPFLAGS_CHECKTYPES|Py_TPFLAGS_HAVE_NEWBUFFER|Py_TPFLAGS_HAVE_GC, /*tp_flags*/
  0, /*tp_doc*/
  __pyx_tp_traverse_13_rnaseq_utils___pyx_scope_struct_4_read_generator, /*tp_traverse*/
  0, /*tp_clear*/
  0, /*tp_richcompare*/
  0, /*tp_weaklistoffset*/
  0, /*tp_iter*/
  0, /*tp_iternext*/
  0, /*tp_methods*/
  0, /*tp_members*/
  0, /*tp_getset*/
  0, /*tp_base*/
  0, /*tp_dict*/
  0, /*tp_descr_get*/
  0, /*tp_descr_set*/
  0, /*tp_dictoffset*/
  0, /*tp_init*/
  0, /*tp_alloc*/
  __pyx_tp_new_13_rnaseq_utils___pyx_scope_struct_4_read_generator, /*tp_new*/
  0, /*tp_free*/
  0, /*tp_is_gc*/
  0, /*tp_bases*/
  0, /*tp_mro*/
  0, /*tp_cache*/
  0, /*tp_subclasses*/
  0, /*tp_weaklist*/
  0, /*tp_del*/
  0, /*tp_version_tag*/
  #if PY_VERSION_HEX >= 0x030400a1
  0, /*tp_finalize*/
  #endif
  #if PY_VERSION_HEX >= 0x030800b1
  0, /*tp_vectorcall*/
  #endif
};
static struct __pyx_vtabstruct_array __pyx_vtable_array;

static PyObject *__pyx_tp_new_array(PyTypeObject *t, PyObject *a, PyObject *k) {
  struct __pyx_array_obj *p;
  PyObject *o;
  if (likely((t->tp_flags & Py_TPFLAGS_IS_ABSTRACT) == 0)) {
    o = (*t->tp_alloc)(t, 0);
  } else {
    o = (PyObject *) PyBaseObject_Type.tp_new(t, __pyx_empty_tuple, 0);
  }
  if (unlikely(!o)) return 0;
  p = ((struct __pyx_array_obj *)o);
  p->__pyx_vtab = __pyx_vtabptr_array;
  p->mode = ((PyObject*)Py_None); Py_INCREF(Py_None);
  p->_format = ((PyObject*)Py_None); Py_INCREF(Py_None);
  if (unlikely(__pyx_array___cinit__(o, a, k) < 0)) goto bad;
  return o;
  bad:
  Py_DECREF(o); o = 0;
  return NULL;
}

static void __pyx_tp_dealloc_array(PyObject *o) {
  struct __pyx_array_obj *p = (struct __pyx_array_obj *)o;
  #if CYTHON_USE_TP_FINALIZE
  if (unlikely(PyType_HasFeature(Py_TYPE(o), Py_TPFLAGS_HAVE_FINALIZE) && Py_TYPE(o)->tp_finalize) && (!PyType_IS_GC(Py_TYPE(o)) || !_PyGC_FINALIZED(o))) {
    if (PyObject_CallFinalizerFromDealloc(o)) return;
  }
  #endif
  {
    PyObject *etype, *eval, *etb;
    PyErr_Fetch(&etype, &eval, &etb);
    ++Py_REFCNT(o);
    __pyx_array___dealloc__(o);
    --Py_REFCNT(o);
    PyErr_Restore(etype, eval, etb);
  }
  Py_CLEAR(p->mode);
  Py_CLEAR(p->_format);
  (*Py_TYPE(o)->tp_free)(o);
}
static PyObject *__pyx_sq_item_array(PyObject *o, Py_ssize_t i) {
  PyObject *r;
  PyObject *x = PyInt_FromSsize_t(i); if(!x) return 0;
  r = Py_TYPE(o)->tp_as_mapping->mp_subscript(o, x);
  Py_DECREF(x);
  return r;
}

static int __pyx_mp_ass_subscript_array(PyObject *o, PyObject *i, PyObject *v) {
  if (v) {
    return __pyx_array___setitem__(o, i, v);
  }
  else {
    PyErr_Format(PyExc_NotImplementedError,
      "Subscript deletion not supported by %.200s", Py_TYPE(o)->tp_name);
    return -1;
  }
}

static PyObject *__pyx_tp_getattro_array(PyObject *o, PyObject *n) {
  PyObject *v = __Pyx_PyObject_GenericGetAttr(o, n);
  if (!v && PyErr_ExceptionMatches(PyExc_AttributeError)) {
    PyErr_Clear();
    v = __pyx_array___getattr__(o, n);
  }
  return v;
}

static PyObject *__pyx_getprop___pyx_array_memview(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_15View_dot_MemoryView_5array_7memview_1__get__(o);
}

static PyMethodDef __pyx_methods_array[] = {
  {"__getattr__", (PyCFunction)__pyx_array___getattr__, METH_O|METH_COEXIST, 0},
  {"__reduce_cython__", (PyCFunction)__pyx_pw___pyx_array_1__reduce_cython__, METH_NOARGS, 0},
  {"__setstate_cython__", (PyCFunction)__pyx_pw___pyx_array_3__setstate_cython__, METH_O, 0},
  {0, 0, 0, 0}
};

static struct PyGetSetDef __pyx_getsets_array[] = {
  {(char *)"memview", __pyx_getprop___pyx_array_memview, 0, (char *)0, 0},
  {0, 0, 0, 0, 0}
};

static PySequenceMethods __pyx_tp_as_sequence_array = {
  __pyx_array___len__, /*sq_length*/
  0, /*sq_concat*/
  0, /*sq_repeat*/
  __pyx_sq_item_array, /*sq_item*/
  0, /*sq_slice*/
  0, /*sq_ass_item*/
  0, /*sq_ass_slice*/
  0, /*sq_contains*/
  0, /*sq_inplace_concat*/
  0, /*sq_inplace_repeat*/
};

static PyMappingMethods __pyx_tp_as_mapping_array = {
  __pyx_array___len__, /*mp_length*/
  __pyx_array___getitem__, /*mp_subscript*/
  __pyx_mp_ass_subscript_array, /*mp_ass_subscript*/
};

static PyBufferProcs __pyx_tp_as_buffer_array = {
  #if PY_MAJOR_VERSION < 3
  0, /*bf_getreadbuffer*/
  #endif
  #if PY_MAJOR_VERSION < 3
  0, /*bf_getwritebuffer*/
  #endif
  #if PY_MAJOR_VERSION < 3
  0, /*bf_getsegcount*/
  #endif
  #if PY_MAJOR_VERSION < 3
  0, /*bf_getcharbuffer*/
  #endif
  __pyx_array_getbuffer, /*bf_getbuffer*/
  0, /*bf_releasebuffer*/
};

static PyTypeObject __pyx_type___pyx_array = {
  PyVarObject_HEAD_INIT(0, 0)
  "_rnaseq_utils.array", /*tp_name*/
  sizeof(struct __pyx_array_obj), /*tp_basicsize*/
  0, /*tp_itemsize*/
  __pyx_tp_dealloc_array, /*tp_dealloc*/
  0, /*tp_print*/
  0, /*tp_getattr*/
  0, /*tp_setattr*/
  #if PY_MAJOR_VERSION < 3
  0, /*tp_compare*/
  #endif
  #if PY_MAJOR_VERSION >= 3
  0, /*tp_as_async*/
  #endif
  0, /*tp_repr*/
  0, /*tp_as_number*/
  &__pyx_tp_as_sequence_array, /*tp_as_sequence*/
  &__pyx_tp_as_mapping_array, /*tp_as_mapping*/
  0, /*tp_hash*/
  0, /*tp_call*/
  0, /*tp_str*/
  __pyx_tp_getattro_array, /*tp_getattro*/
  0, /*tp_setattro*/
  &__pyx_tp_as_buffer_array, /*tp_as_buffer*/
  Py_TPFLAGS_DEFAULT|Py_TPFLAGS_HAVE_VERSION_TAG|Py_TPFLAGS_CHECKTYPES|Py_TPFLAGS_HAVE_NEWBUFFER|Py_TPFLAGS_BASETYPE, /*tp_flags*/
  0, /*tp_doc*/
  0, /*tp_traverse*/
  0, /*tp_clear*/
  0, /*tp_richcompare*/
  0, /*tp_weaklistoffset*/
  0, /*tp_iter*/
  0, /*tp_iternext*/
  __pyx_methods_array, /*tp_methods*/
  0, /*tp_members*/
  __pyx_getsets_array, /*tp_getset*/
  0, /*tp_base*/
  0, /*tp_dict*/
  0, /*tp_descr_get*/
  0, /*tp_descr_set*/
  0, /*tp_dictoffset*/
  0, /*tp_init*/
  0, /*tp_alloc*/
  __pyx_tp_new_array, /*tp_new*/
  0, /*tp_free*/
  0, /*tp_is_gc*/
  0, /*tp_bases*/
  0, /*tp_mro*/
  0, /*tp_cache*/
  0, /*tp_subclasses*/
  0, /*tp_weaklist*/
  0, /*tp_del*/
  0, /*tp_version_tag*/
  #if PY_VERSION_HEX >= 0x030400a1
  0, /*tp_finalize*/
  #endif
  #if PY_VERSION_HEX >= 0x030800b1
  0, /*tp_vectorcall*/
  #endif
};

static PyObject *__pyx_tp_new_Enum(PyTypeObject *t, CYTHON_UNUSED PyObject *a, CYTHON_UNUSED PyObject *k) {
  struct __pyx_MemviewEnum_obj *p;
  PyObject *o;
  if (likely((t->tp_flags & Py_TPFLAGS_IS_ABSTRACT) == 0)) {
    o = (*t->tp_alloc)(t, 0);
  } else {
    o = (PyObject *) PyBaseObject_Type.tp_new(t, __pyx_empty_tuple, 0);
  }
  if (unlikely(!o)) return 0;
  p = ((struct __pyx_MemviewEnum_obj *)o);
  p->name = Py_None; Py_INCREF(Py_None);
  return o;
}

static void __pyx_tp_dealloc_Enum(PyObject *o) {
  struct __pyx_MemviewEnum_obj *p = (struct __pyx_MemviewEnum_obj *)o;
  #if CYTHON_USE_TP_FINALIZE
  if (unlikely(PyType_HasFeature(Py_TYPE(o), Py_TPFLAGS_HAVE_FINALIZE) && Py_TYPE(o)->tp_finalize) && !_PyGC_FINALIZED(o)) {
    if (PyObject_CallFinalizerFromDealloc(o)) return;
  }
  #endif
  PyObject_GC_UnTrack(o);
  Py_CLEAR(p->name);
  (*Py_TYPE(o)->tp_free)(o);
}

static int __pyx_tp_traverse_Enum(PyObject *o, visitproc v, void *a) {
  int e;
  struct __pyx_MemviewEnum_obj *p = (struct __pyx_MemviewEnum_obj *)o;
  if (p->name) {
    e = (*v)(p->name, a); if (e) return e;
  }
  return 0;
}

static int __pyx_tp_clear_Enum(PyObject *o) {
  PyObject* tmp;
  struct __pyx_MemviewEnum_obj *p = (struct __pyx_MemviewEnum_obj *)o;
  tmp = ((PyObject*)p->name);
  p->name = Py_None; Py_INCREF(Py_None);
  Py_XDECREF(tmp);
  return 0;
}

static PyMethodDef __pyx_methods_Enum[] = {
  {"__reduce_cython__", (PyCFunction)__pyx_pw___pyx_MemviewEnum_1__reduce_cython__, METH_NOARGS, 0},
  {"__setstate_cython__", (PyCFunction)__pyx_pw___pyx_MemviewEnum_3__setstate_cython__, METH_O, 0},
  {0, 0, 0, 0}
};

static PyTypeObject __pyx_type___pyx_MemviewEnum = {
  PyVarObject_HEAD_INIT(0, 0)
  "_rnaseq_utils.Enum", /*tp_name*/
  sizeof(struct __pyx_MemviewEnum_obj), /*tp_basicsize*/
  0, /*tp_itemsize*/
  __pyx_tp_dealloc_Enum, /*tp_dealloc*/
  0, /*tp_print*/
  0, /*tp_getattr*/
  0, /*tp_setattr*/
  #if PY_MAJOR_VERSION < 3
  0, /*tp_compare*/
  #endif
  #if PY_MAJOR_VERSION >= 3
  0, /*tp_as_async*/
  #endif
  __pyx_MemviewEnum___repr__, /*tp_repr*/
  0, /*tp_as_number*/
  0, /*tp_as_sequence*/
  0, /*tp_as_mapping*/
  0, /*tp_hash*/
  0, /*tp_call*/
  0, /*tp_str*/
  0, /*tp_getattro*/
  0, /*tp_setattro*/
  0, /*tp_as_buffer*/
  Py_TPFLAGS_DEFAULT|Py_TPFLAGS_HAVE_VERSION_TAG|Py_TPFLAGS_CHECKTYPES|Py_TPFLAGS_HAVE_NEWBUFFER|Py_TPFLAGS_BASETYPE|Py_TPFLAGS_HAVE_GC, /*tp_flags*/
  0, /*tp_doc*/
  __pyx_tp_traverse_Enum, /*tp_traverse*/
  __pyx_tp_clear_Enum, /*tp_clear*/
  0, /*tp_richcompare*/
  0, /*tp_weaklistoffset*/
  0, /*tp_iter*/
  0, /*tp_iternext*/
  __pyx_methods_Enum, /*tp_methods*/
  0, /*tp_members*/
  0, /*tp_getset*/
  0, /*tp_base*/
  0, /*tp_dict*/
  0, /*tp_descr_get*/
  0, /*tp_descr_set*/
  0, /*tp_dictoffset*/
  __pyx_MemviewEnum___init__, /*tp_init*/
  0, /*tp_alloc*/
  __pyx_tp_new_Enum, /*tp_new*/
  0, /*tp_free*/
  0, /*tp_is_gc*/
  0, /*tp_bases*/
  0, /*tp_mro*/
  0, /*tp_cache*/
  0, /*tp_subclasses*/
  0, /*tp_weaklist*/
  0, /*tp_del*/
  0, /*tp_version_tag*/
  #if PY_VERSION_HEX >= 0x030400a1
  0, /*tp_finalize*/
  #endif
  #if PY_VERSION_HEX >= 0x030800b1
  0, /*tp_vectorcall*/
  #endif
};
static struct __pyx_vtabstruct_memoryview __pyx_vtable_memoryview;

static PyObject *__pyx_tp_new_memoryview(PyTypeObject *t, PyObject *a, PyObject *k) {
  struct __pyx_memoryview_obj *p;
  PyObject *o;
  if (likely((t->tp_flags & Py_TPFLAGS_IS_ABSTRACT) == 0)) {
    o = (*t->tp_alloc)(t, 0);
  } else {
    o = (PyObject *) PyBaseObject_Type.tp_new(t, __pyx_empty_tuple, 0);
  }
  if (unlikely(!o)) return 0;
  p = ((struct __pyx_memoryview_obj *)o);
  p->__pyx_vtab = __pyx_vtabptr_memoryview;
  p->obj = Py_None; Py_INCREF(Py_None);
  p->_size = Py_None; Py_INCREF(Py_None);
  p->_array_interface = Py_None; Py_INCREF(Py_None);
  p->view.obj = NULL;
  if (unlikely(__pyx_memoryview___cinit__(o, a, k) < 0)) goto bad;
  return o;
  bad:
  Py_DECREF(o); o = 0;
  return NULL;
}

static void __pyx_tp_dealloc_memoryview(PyObject *o) {
  struct __pyx_memoryview_obj *p = (struct __pyx_memoryview_obj *)o;
  #if CYTHON_USE_TP_FINALIZE
  if (unlikely(PyType_HasFeature(Py_TYPE(o), Py_TPFLAGS_HAVE_FINALIZE) && Py_TYPE(o)->tp_finalize) && !_PyGC_FINALIZED(o)) {
    if (PyObject_CallFinalizerFromDealloc(o)) return;
  }
  #endif
  PyObject_GC_UnTrack(o);
  {
    PyObject *etype, *eval, *etb;
    PyErr_Fetch(&etype, &eval, &etb);
    ++Py_REFCNT(o);
    __pyx_memoryview___dealloc__(o);
    --Py_REFCNT(o);
    PyErr_Restore(etype, eval, etb);
  }
  Py_CLEAR(p->obj);
  Py_CLEAR(p->_size);
  Py_CLEAR(p->_array_interface);
  (*Py_TYPE(o)->tp_free)(o);
}

static int __pyx_tp_traverse_memoryview(PyObject *o, visitproc v, void *a) {
  int e;
  struct __pyx_memoryview_obj *p = (struct __pyx_memoryview_obj *)o;
  if (p->obj) {
    e = (*v)(p->obj, a); if (e) return e;
  }
  if (p->_size) {
    e = (*v)(p->_size, a); if (e) return e;
  }
  if (p->_array_interface) {
    e = (*v)(p->_array_interface, a); if (e) return e;
  }
  if (p->view.obj) {
    e = (*v)(p->view.obj, a); if (e) return e;
  }
  return 0;
}

static int __pyx_tp_clear_memoryview(PyObject *o) {
  PyObject* tmp;
  struct __pyx_memoryview_obj *p = (struct __pyx_memoryview_obj *)o;
  tmp = ((PyObject*)p->obj);
  p->obj = Py_None; Py_INCREF(Py_None);
  Py_XDECREF(tmp);
  tmp = ((PyObject*)p->_size);
  p->_size = Py_None; Py_INCREF(Py_None);
  Py_XDECREF(tmp);
  tmp = ((PyObject*)p->_array_interface);
  p->_array_interface = Py_None; Py_INCREF(Py_None);
  Py_XDECREF(tmp);
  Py_CLEAR(p->view.obj);
  return 0;
}
static PyObject *__pyx_sq_item_memoryview(PyObject *o, Py_ssize_t i) {
  PyObject *r;
  PyObject *x = PyInt_FromSsize_t(i); if(!x) return 0;
  r = Py_TYPE(o)->tp_as_mapping->mp_subscript(o, x);
  Py_DECREF(x);
  return r;
}

static int __pyx_mp_ass_subscript_memoryview(PyObject *o, PyObject *i, PyObject *v) {
  if (v) {
    return __pyx_memoryview___setitem__(o, i, v);
  }
  else {
    PyErr_Format(PyExc_NotImplementedError,
      "Subscript deletion not supported by %.200s", Py_TYPE(o)->tp_name);
    return -1;
  }
}

static PyObject *__pyx_getprop___pyx_memoryview_T(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_15View_dot_MemoryView_10memoryview_1T_1__get__(o);
}

static PyObject *__pyx_getprop___pyx_memoryview_base(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_15View_dot_MemoryView_10memoryview_4base_1__get__(o);
}

static PyObject *__pyx_getprop___pyx_memoryview_shape(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_15View_dot_MemoryView_10memoryview_5shape_1__get__(o);
}

static PyObject *__pyx_getprop___pyx_memoryview_strides(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_15View_dot_MemoryView_10memoryview_7strides_1__get__(o);
}

static PyObject *__pyx_getprop___pyx_memoryview_suboffsets(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_15View_dot_MemoryView_10memoryview_10suboffsets_1__get__(o);
}

static PyObject *__pyx_getprop___pyx_memoryview_ndim(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_15View_dot_MemoryView_10memoryview_4ndim_1__get__(o);
}

static PyObject *__pyx_getprop___pyx_memoryview_itemsize(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_15View_dot_MemoryView_10memoryview_8itemsize_1__get__(o);
}

static PyObject *__pyx_getprop___pyx_memoryview_nbytes(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_15View_dot_MemoryView_10memoryview_6nbytes_1__get__(o);
}

static PyObject *__pyx_getprop___pyx_memoryview_size(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_15View_dot_MemoryView_10memoryview_4size_1__get__(o);
}

static PyMethodDef __pyx_methods_memoryview[] = {
  {"is_c_contig", (PyCFunction)__pyx_memoryview_is_c_contig, METH_NOARGS, 0},
  {"is_f_contig", (PyCFunction)__pyx_memoryview_is_f_contig, METH_NOARGS, 0},
  {"copy", (PyCFunction)__pyx_memoryview_copy, METH_NOARGS, 0},
  {"copy_fortran", (PyCFunction)__pyx_memoryview_copy_fortran, METH_NOARGS, 0},
  {"__reduce_cython__", (PyCFunction)__pyx_pw___pyx_memoryview_1__reduce_cython__, METH_NOARGS, 0},
  {"__setstate_cython__", (PyCFunction)__pyx_pw___pyx_memoryview_3__setstate_cython__, METH_O, 0},
  {0, 0, 0, 0}
};

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  {(char *)"shape", __pyx_getprop___pyx_memoryview_shape, 0, (char *)0, 0},
  {(char *)"strides", __pyx_getprop___pyx_memoryview_strides, 0, (char *)0, 0},
  {(char *)"suboffsets", __pyx_getprop___pyx_memoryview_suboffsets, 0, (char *)0, 0},
  {(char *)"ndim", __pyx_getprop___pyx_memoryview_ndim, 0, (char *)0, 0},
  {(char *)"itemsize", __pyx_getprop___pyx_memoryview_itemsize, 0, (char *)0, 0},
  {(char *)"nbytes", __pyx_getprop___pyx_memoryview_nbytes, 0, (char *)0, 0},
  {(char *)"size", __pyx_getprop___pyx_memoryview_size, 0, (char *)0, 0},
  {0, 0, 0, 0, 0}
};

static PySequenceMethods __pyx_tp_as_sequence_memoryview = {
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  0, /*sq_concat*/
  0, /*sq_repeat*/
  __pyx_sq_item_memoryview, /*sq_item*/
  0, /*sq_slice*/
  0, /*sq_ass_item*/
  0, /*sq_ass_slice*/
  0, /*sq_contains*/
  0, /*sq_inplace_concat*/
  0, /*sq_inplace_repeat*/
};

static PyMappingMethods __pyx_tp_as_mapping_memoryview = {
  __pyx_memoryview___len__, /*mp_length*/
  __pyx_memoryview___getitem__, /*mp_subscript*/
  __pyx_mp_ass_subscript_memoryview, /*mp_ass_subscript*/
};

static PyBufferProcs __pyx_tp_as_buffer_memoryview = {
  #if PY_MAJOR_VERSION < 3
  0, /*bf_getreadbuffer*/
  #endif
  #if PY_MAJOR_VERSION < 3
  0, /*bf_getwritebuffer*/
  #endif
  #if PY_MAJOR_VERSION < 3
  0, /*bf_getsegcount*/
  #endif
  #if PY_MAJOR_VERSION < 3
  0, /*bf_getcharbuffer*/
  #endif
  __pyx_memoryview_getbuffer, /*bf_getbuffer*/
  0, /*bf_releasebuffer*/
};

static PyTypeObject __pyx_type___pyx_memoryview = {
  PyVarObject_HEAD_INIT(0, 0)
  "_rnaseq_utils.memoryview", /*tp_name*/
  sizeof(struct __pyx_memoryview_obj), /*tp_basicsize*/
  0, /*tp_itemsize*/
  __pyx_tp_dealloc_memoryview, /*tp_dealloc*/
  0, /*tp_print*/
  0, /*tp_getattr*/
  0, /*tp_setattr*/
  #if PY_MAJOR_VERSION < 3
  0, /*tp_compare*/
  #endif
  #if PY_MAJOR_VERSION >= 3
  0, /*tp_as_async*/
  #endif
  __pyx_memoryview___repr__, /*tp_repr*/
  0, /*tp_as_number*/
  &__pyx_tp_as_sequence_memoryview, /*tp_as_sequence*/
  &__pyx_tp_as_mapping_memoryview, /*tp_as_mapping*/
  0, /*tp_hash*/
  0, /*tp_call*/
  __pyx_memoryview___str__, /*tp_str*/
  0, /*tp_getattro*/
  0, /*tp_setattro*/
  &__pyx_tp_as_buffer_memoryview, /*tp_as_buffer*/
  Py_TPFLAGS_DEFAULT|Py_TPFLAGS_HAVE_VERSION_TAG|Py_TPFLAGS_CHECKTYPES|Py_TPFLAGS_HAVE_NEWBUFFER|Py_TPFLAGS_BASETYPE|Py_TPFLAGS_HAVE_GC, /*tp_flags*/
  0, /*tp_doc*/
  __pyx_tp_traverse_memoryview, /*tp_traverse*/
  __pyx_tp_clear_memoryview, /*tp_clear*/
  0, /*tp_richcompare*/
  0, /*tp_weaklistoffset*/
  0, /*tp_iter*/
  0, /*tp_iternext*/
  __pyx_methods_memoryview, /*tp_methods*/
  0, /*tp_members*/
  __pyx_getsets_memoryview, /*tp_getset*/
  0, /*tp_base*/
  0, /*tp_dict*/
  0, /*tp_descr_get*/
  0, /*tp_descr_set*/
  0, /*tp_dictoffset*/
  0, /*tp_init*/
  0, /*tp_alloc*/
  __pyx_tp_new_memoryview, /*tp_new*/
  0, /*tp_free*/
  0, /*tp_is_gc*/
  0, /*tp_bases*/
  0, /*tp_mro*/
  0, /*tp_cache*/
  0, /*tp_subclasses*/
  0, /*tp_weaklist*/
  0, /*tp_del*/
  0, /*tp_version_tag*/
  #if PY_VERSION_HEX >= 0x030400a1
  0, /*tp_finalize*/
  #endif
  #if PY_VERSION_HEX >= 0x030800b1
  0, /*tp_vectorcall*/
  #endif
};
static struct __pyx_vtabstruct__memoryviewslice __pyx_vtable__memoryviewslice;

static PyObject *__pyx_tp_new__memoryviewslice(PyTypeObject *t, PyObject *a, PyObject *k) {
  struct __pyx_memoryviewslice_obj *p;
  PyObject *o = __pyx_tp_new_memoryview(t, a, k);
  if (unlikely(!o)) return 0;
  p = ((struct __pyx_memoryviewslice_obj *)o);
  p->__pyx_base.__pyx_vtab = (struct __pyx_vtabstruct_memoryview*)__pyx_vtabptr__memoryviewslice;
  p->from_object = Py_None; Py_INCREF(Py_None);
  p->from_slice.memview = NULL;
  return o;
}

static void __pyx_tp_dealloc__memoryviewslice(PyObject *o) {
  struct __pyx_memoryviewslice_obj *p = (struct __pyx_memoryviewslice_obj *)o;
  #if CYTHON_USE_TP_FINALIZE
  if (unlikely(PyType_HasFeature(Py_TYPE(o), Py_TPFLAGS_HAVE_FINALIZE) && Py_TYPE(o)->tp_finalize) && !_PyGC_FINALIZED(o)) {
    if (PyObject_CallFinalizerFromDealloc(o)) return;
  }
  #endif
  PyObject_GC_UnTrack(o);
  {
    PyObject *etype, *eval, *etb;
    PyErr_Fetch(&etype, &eval, &etb);
    ++Py_REFCNT(o);
    __pyx_memoryviewslice___dealloc__(o);
    --Py_REFCNT(o);
    PyErr_Restore(etype, eval, etb);
  }
  Py_CLEAR(p->from_object);
  PyObject_GC_Track(o);
  __pyx_tp_dealloc_memoryview(o);
}

static int __pyx_tp_traverse__memoryviewslice(PyObject *o, visitproc v, void *a) {
  int e;
  struct __pyx_memoryviewslice_obj *p = (struct __pyx_memoryviewslice_obj *)o;
  e = __pyx_tp_traverse_memoryview(o, v, a); if (e) return e;
  if (p->from_object) {
    e = (*v)(p->from_object, a); if (e) return e;
  }
  return 0;
}

static int __pyx_tp_clear__memoryviewslice(PyObject *o) {
  PyObject* tmp;
  struct __pyx_memoryviewslice_obj *p = (struct __pyx_memoryviewslice_obj *)o;
  __pyx_tp_clear_memoryview(o);
  tmp = ((PyObject*)p->from_object);
  p->from_object = Py_None; Py_INCREF(Py_None);
  Py_XDECREF(tmp);
  __PYX_XDEC_MEMVIEW(&p->from_slice, 1);
  return 0;
}

static PyObject *__pyx_getprop___pyx_memoryviewslice_base(PyObject *o, CYTHON_UNUSED void *x) {
  return __pyx_pw_15View_dot_MemoryView_16_memoryviewslice_4base_1__get__(o);
}

static PyMethodDef __pyx_methods__memoryviewslice[] = {
  {"__reduce_cython__", (PyCFunction)__pyx_pw___pyx_memoryviewslice_1__reduce_cython__, METH_NOARGS, 0},
  {"__setstate_cython__", (PyCFunction)__pyx_pw___pyx_memoryviewslice_3__setstate_cython__, METH_O, 0},
  {0, 0, 0, 0}
};

static struct PyGetSetDef __pyx_getsets__memoryviewslice[] = {
  {(char *)"base", __pyx_getprop___pyx_memoryviewslice_base, 0, (char *)0, 0},
  {0, 0, 0, 0, 0}
};

static PyTypeObject __pyx_type___pyx_memoryviewslice = {
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  sizeof(struct __pyx_memoryviewslice_obj), /*tp_basicsize*/
  0, /*tp_itemsize*/
  __pyx_tp_dealloc__memoryviewslice, /*tp_dealloc*/
  0, /*tp_print*/
  0, /*tp_getattr*/
  0, /*tp_setattr*/
  #if PY_MAJOR_VERSION < 3
  0, /*tp_compare*/
  #endif
  #if PY_MAJOR_VERSION >= 3
  0, /*tp_as_async*/
  #endif
  #if CYTHON_COMPILING_IN_PYPY
  __pyx_memoryview___repr__, /*tp_repr*/
  #else
  0, /*tp_repr*/
  #endif
  0, /*tp_as_number*/
  0, /*tp_as_sequence*/
  0, /*tp_as_mapping*/
  0, /*tp_hash*/
  0, /*tp_call*/
  #if CYTHON_COMPILING_IN_PYPY
  __pyx_memoryview___str__, /*tp_str*/
  #else
  0, /*tp_str*/
  #endif
  0, /*tp_getattro*/
  0, /*tp_setattro*/
  0, /*tp_as_buffer*/
  Py_TPFLAGS_DEFAULT|Py_TPFLAGS_HAVE_VERSION_TAG|Py_TPFLAGS_CHECKTYPES|Py_TPFLAGS_HAVE_NEWBUFFER|Py_TPFLAGS_BASETYPE|Py_TPFLAGS_HAVE_GC, /*tp_flags*/
  "Internal class for passing memoryview slices to Python", /*tp_doc*/
  __pyx_tp_traverse__memoryviewslice, /*tp_traverse*/
  __pyx_tp_clear__memoryviewslice, /*tp_clear*/
  0, /*tp_richcompare*/
  0, /*tp_weaklistoffset*/
  0, /*tp_iter*/
  0, /*tp_iternext*/
  __pyx_methods__memoryviewslice, /*tp_methods*/
  0, /*tp_members*/
  __pyx_getsets__memoryviewslice, /*tp_getset*/
  0, /*tp_base*/
  0, /*tp_dict*/
  0, /*tp_descr_get*/
  0, /*tp_descr_set*/
  0, /*tp_dictoffset*/
  0, /*tp_init*/
  0, /*tp_alloc*/
  __pyx_tp_new__memoryviewslice, /*tp_new*/
  0, /*tp_free*/
  0, /*tp_is_gc*/
  0, /*tp_bases*/
  0, /*tp_mro*/
  0, /*tp_cache*/
  0, /*tp_subclasses*/
  0, /*tp_weaklist*/
  0, /*tp_del*/
  0, /*tp_version_tag*/
  #if PY_VERSION_HEX >= 0x030400a1
  0, /*tp_finalize*/
  #endif
  #if PY_VERSION_HEX >= 0x030800b1
  0, /*tp_vectorcall*/
  #endif
};

static PyMethodDef __pyx_methods[] = {
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  {"flatten", (PyCFunction)__pyx_pw_13_rnaseq_utils_6flatten, METH_O, 0},
  {"collapse_blocks", (PyCFunction)__pyx_pw_13_rnaseq_utils_8collapse_blocks, METH_O, __pyx_doc_13_rnaseq_utils_7collapse_blocks},
  {"elr_to_readobject", (PyCFunction)__pyx_pw_13_rnaseq_utils_10elr_to_readobject, METH_O, __pyx_doc_13_rnaseq_utils_9elr_to_readobject},
  {"range_of_reads", (PyCFunction)__pyx_pw_13_rnaseq_utils_12range_of_reads, METH_O, __pyx_doc_13_rnaseq_utils_11range_of_reads},
  {"calculate_coverage", (PyCFunction)(void*)(PyCFunctionWithKeywords)__pyx_pw_13_rnaseq_utils_14calculate_coverage, METH_VARARGS|METH_KEYWORDS, __pyx_doc_13_rnaseq_utils_13calculate_coverage},
  {"get_flank", (PyCFunction)(void*)(PyCFunctionWithKeywords)__pyx_pw_13_rnaseq_utils_19get_flank, METH_VARARGS|METH_KEYWORDS, __pyx_doc_13_rnaseq_utils_18get_flank},
  {"parse_SAM_CIGAR", (PyCFunction)(void*)(PyCFunctionWithKeywords)__pyx_pw_13_rnaseq_utils_24parse_SAM_CIGAR, METH_VARARGS|METH_KEYWORDS, __pyx_doc_13_rnaseq_utils_23parse_SAM_CIGAR},
  {"get_max_deltas", (PyCFunction)(void*)(PyCFunctionWithKeywords)__pyx_pw_13_rnaseq_utils_29get_max_deltas, METH_VARARGS|METH_KEYWORDS, __pyx_doc_13_rnaseq_utils_28get_max_deltas},
  {"get_gaps", (PyCFunction)(void*)(PyCFunctionWithKeywords)__pyx_pw_13_rnaseq_utils_31get_gaps, METH_VARARGS|METH_KEYWORDS, __pyx_doc_13_rnaseq_utils_30get_gaps},
  {0, 0, 0, 0}
};

#if PY_MAJOR_VERSION >= 3
#if CYTHON_PEP489_MULTI_PHASE_INIT
static PyObject* __pyx_pymod_create(PyObject *spec, PyModuleDef *def); /*proto*/
static int __pyx_pymod_exec__rnaseq_utils(PyObject* module); /*proto*/
static PyModuleDef_Slot __pyx_moduledef_slots[] = {
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  {Py_mod_exec, (void*)__pyx_pymod_exec__rnaseq_utils},
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};
#endif

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  /* "_rnaseq_utils.pyx":882
 *         new_read = RNAseqMapping(input_data)
 *         bed_elements = line.rstrip().split('\t')
 *         new_read.attributes['gene_id'] = '.'.join(bed_elements[3].split('.')[:-1])             # <<<<<<<<<<<<<<
 *         new_read.attributes['transcript_id'] = bed_elements[3]
 *         new_read.attributes['S.reads'] = new_read.weight if new_read.s_tag else 0
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  /* "_rnaseq_utils.pyx":1165
 *                 e_tag = True
 * 
 *             splice = [True if i=='D' else False for i in label[1:-1:2]]             # <<<<<<<<<<<<<<
 *         elif strand == -1:
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  /* "_rnaseq_utils.pyx":1450
 *                     mismatches += 1
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 */
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 * 
 *     total_count = 0
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 *         self.bp_minus = OrderedArray(donors + acceptors)
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 * def split_chunk(list reads, float minimum_proportion, int max_gap):             # <<<<<<<<<<<<<<
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  /* "_rnaseq_utils.pyx":1351
 *     return strand
 * 
 * def parse_MD_string(str mdstring):             # <<<<<<<<<<<<<<
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  /* "(tree fragment)":11
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 *     __pyx_result.name = __pyx_state[0]
 *     if len(__pyx_state) > 1 and hasattr(__pyx_result, '__dict__'):
 */

  /*--- Wrapped vars code ---*/

  goto __pyx_L0;
  __pyx_L1_error:;
  __Pyx_XDECREF(__pyx_t_1);
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  if (__pyx_m) {
    if (__pyx_d) {
      __Pyx_AddTraceback("init _rnaseq_utils", __pyx_clineno, __pyx_lineno, __pyx_filename);
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    Py_CLEAR(__pyx_m);
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  return (__pyx_m != NULL) ? 0 : -1;
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/* --- Runtime support code --- */
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#if CYTHON_REFNANNY
static __Pyx_RefNannyAPIStruct *__Pyx_RefNannyImportAPI(const char *modname) {
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/* PyObjectGetAttrStr */
#if CYTHON_USE_TYPE_SLOTS
static CYTHON_INLINE PyObject* __Pyx_PyObject_GetAttrStr(PyObject* obj, PyObject* attr_name) {
    PyTypeObject* tp = Py_TYPE(obj);
    if (likely(tp->tp_getattro))
        return tp->tp_getattro(obj, attr_name);
#if PY_MAJOR_VERSION < 3
    if (likely(tp->tp_getattr))
        return tp->tp_getattr(obj, PyString_AS_STRING(attr_name));
#endif
    return PyObject_GetAttr(obj, attr_name);
}
#endif

/* GetBuiltinName */
static PyObject *__Pyx_GetBuiltinName(PyObject *name) {
    PyObject* result = __Pyx_PyObject_GetAttrStr(__pyx_b, name);
    if (unlikely(!result)) {
        PyErr_Format(PyExc_NameError,
#if PY_MAJOR_VERSION >= 3
            "name '%U' is not defined", name);
#else
            "name '%.200s' is not defined", PyString_AS_STRING(name));
#endif
    }
    return result;
}

/* RaiseDoubleKeywords */
static void __Pyx_RaiseDoubleKeywordsError(
    const char* func_name,
    PyObject* kw_name)
{
    PyErr_Format(PyExc_TypeError,
        #if PY_MAJOR_VERSION >= 3
        "%s() got multiple values for keyword argument '%U'", func_name, kw_name);
        #else
        "%s() got multiple values for keyword argument '%s'", func_name,
        PyString_AsString(kw_name));
        #endif
}

/* ParseKeywords */
static int __Pyx_ParseOptionalKeywords(
    PyObject *kwds,
    PyObject **argnames[],
    PyObject *kwds2,
    PyObject *values[],
    Py_ssize_t num_pos_args,
    const char* function_name)
{
    PyObject *key = 0, *value = 0;
    Py_ssize_t pos = 0;
    PyObject*** name;
    PyObject*** first_kw_arg = argnames + num_pos_args;
    while (PyDict_Next(kwds, &pos, &key, &value)) {
        name = first_kw_arg;
        while (*name && (**name != key)) name++;
        if (*name) {
            values[name-argnames] = value;
            continue;
        }
        name = first_kw_arg;
        #if PY_MAJOR_VERSION < 3
        if (likely(PyString_CheckExact(key)) || likely(PyString_Check(key))) {
            while (*name) {
                if ((CYTHON_COMPILING_IN_PYPY || PyString_GET_SIZE(**name) == PyString_GET_SIZE(key))
                        && _PyString_Eq(**name, key)) {
                    values[name-argnames] = value;
                    break;
                }
                name++;
            }
            if (*name) continue;
            else {
                PyObject*** argname = argnames;
                while (argname != first_kw_arg) {
                    if ((**argname == key) || (
                            (CYTHON_COMPILING_IN_PYPY || PyString_GET_SIZE(**argname) == PyString_GET_SIZE(key))
                             && _PyString_Eq(**argname, key))) {
                        goto arg_passed_twice;
                    }
                    argname++;
                }
            }
        } else
        #endif
        if (likely(PyUnicode_Check(key))) {
            while (*name) {
                int cmp = (**name == key) ? 0 :
                #if !CYTHON_COMPILING_IN_PYPY && PY_MAJOR_VERSION >= 3
                    (PyUnicode_GET_SIZE(**name) != PyUnicode_GET_SIZE(key)) ? 1 :
                #endif
                    PyUnicode_Compare(**name, key);
                if (cmp < 0 && unlikely(PyErr_Occurred())) goto bad;
                if (cmp == 0) {
                    values[name-argnames] = value;
                    break;
                }
                name++;
            }
            if (*name) continue;
            else {
                PyObject*** argname = argnames;
                while (argname != first_kw_arg) {
                    int cmp = (**argname == key) ? 0 :
                    #if !CYTHON_COMPILING_IN_PYPY && PY_MAJOR_VERSION >= 3
                        (PyUnicode_GET_SIZE(**argname) != PyUnicode_GET_SIZE(key)) ? 1 :
                    #endif
                        PyUnicode_Compare(**argname, key);
                    if (cmp < 0 && unlikely(PyErr_Occurred())) goto bad;
                    if (cmp == 0) goto arg_passed_twice;
                    argname++;
                }
            }
        } else
            goto invalid_keyword_type;
        if (kwds2) {
            if (unlikely(PyDict_SetItem(kwds2, key, value))) goto bad;
        } else {
            goto invalid_keyword;
        }
    }
    return 0;
arg_passed_twice:
    __Pyx_RaiseDoubleKeywordsError(function_name, key);
    goto bad;
invalid_keyword_type:
    PyErr_Format(PyExc_TypeError,
        "%.200s() keywords must be strings", function_name);
    goto bad;
invalid_keyword:
    PyErr_Format(PyExc_TypeError,
    #if PY_MAJOR_VERSION < 3
        "%.200s() got an unexpected keyword argument '%.200s'",
        function_name, PyString_AsString(key));
    #else
        "%s() got an unexpected keyword argument '%U'",
        function_name, key);
    #endif
bad:
    return -1;
}

/* RaiseArgTupleInvalid */
static void __Pyx_RaiseArgtupleInvalid(
    const char* func_name,
    int exact,
    Py_ssize_t num_min,
    Py_ssize_t num_max,
    Py_ssize_t num_found)
{
    Py_ssize_t num_expected;
    const char *more_or_less;
    if (num_found < num_min) {
        num_expected = num_min;
        more_or_less = "at least";
    } else {
        num_expected = num_max;
        more_or_less = "at most";
    }
    if (exact) {
        more_or_less = "exactly";
    }
    PyErr_Format(PyExc_TypeError,
                 "%.200s() takes %.8s %" CYTHON_FORMAT_SSIZE_T "d positional argument%.1s (%" CYTHON_FORMAT_SSIZE_T "d given)",
                 func_name, more_or_less, num_expected,
                 (num_expected == 1) ? "" : "s", num_found);
}

/* pyobject_as_double */
static double __Pyx__PyObject_AsDouble(PyObject* obj) {
    PyObject* float_value;
#if !CYTHON_USE_TYPE_SLOTS
    float_value = PyNumber_Float(obj);  if ((0)) goto bad;
#else
    PyNumberMethods *nb = Py_TYPE(obj)->tp_as_number;
    if (likely(nb) && likely(nb->nb_float)) {
        float_value = nb->nb_float(obj);
        if (likely(float_value) && unlikely(!PyFloat_Check(float_value))) {
            PyErr_Format(PyExc_TypeError,
                "__float__ returned non-float (type %.200s)",
                Py_TYPE(float_value)->tp_name);
            Py_DECREF(float_value);
            goto bad;
        }
    } else if (PyUnicode_CheckExact(obj) || PyBytes_CheckExact(obj)) {
#if PY_MAJOR_VERSION >= 3
        float_value = PyFloat_FromString(obj);
#else
        float_value = PyFloat_FromString(obj, 0);
#endif
    } else {
        PyObject* args = PyTuple_New(1);
        if (unlikely(!args)) goto bad;
        PyTuple_SET_ITEM(args, 0, obj);
        float_value = PyObject_Call((PyObject*)&PyFloat_Type, args, 0);
        PyTuple_SET_ITEM(args, 0, 0);
        Py_DECREF(args);
    }
#endif
    if (likely(float_value)) {
        double value = PyFloat_AS_DOUBLE(float_value);
        Py_DECREF(float_value);
        return value;
    }
bad:
    return (double)-1;
}

/* RaiseTooManyValuesToUnpack */
static CYTHON_INLINE void __Pyx_RaiseTooManyValuesError(Py_ssize_t expected) {
    PyErr_Format(PyExc_ValueError,
                 "too many values to unpack (expected %" CYTHON_FORMAT_SSIZE_T "d)", expected);
}

/* RaiseNeedMoreValuesToUnpack */
static CYTHON_INLINE void __Pyx_RaiseNeedMoreValuesError(Py_ssize_t index) {
    PyErr_Format(PyExc_ValueError,
                 "need more than %" CYTHON_FORMAT_SSIZE_T "d value%.1s to unpack",
                 index, (index == 1) ? "" : "s");
}

/* IterFinish */
static CYTHON_INLINE int __Pyx_IterFinish(void) {
#if CYTHON_FAST_THREAD_STATE
    PyThreadState *tstate = __Pyx_PyThreadState_Current;
    PyObject* exc_type = tstate->curexc_type;
    if (unlikely(exc_type)) {
        if (likely(__Pyx_PyErr_GivenExceptionMatches(exc_type, PyExc_StopIteration))) {
            PyObject *exc_value, *exc_tb;
            exc_value = tstate->curexc_value;
            exc_tb = tstate->curexc_traceback;
            tstate->curexc_type = 0;
            tstate->curexc_value = 0;
            tstate->curexc_traceback = 0;
            Py_DECREF(exc_type);
            Py_XDECREF(exc_value);
            Py_XDECREF(exc_tb);
            return 0;
        } else {
            return -1;
        }
    }
    return 0;
#else
    if (unlikely(PyErr_Occurred())) {
        if (likely(PyErr_ExceptionMatches(PyExc_StopIteration))) {
            PyErr_Clear();
            return 0;
        } else {
            return -1;
        }
    }
    return 0;
#endif
}

/* UnpackItemEndCheck */
static int __Pyx_IternextUnpackEndCheck(PyObject *retval, Py_ssize_t expected) {
    if (unlikely(retval)) {
        Py_DECREF(retval);
        __Pyx_RaiseTooManyValuesError(expected);
        return -1;
    } else {
        return __Pyx_IterFinish();
    }
    return 0;
}

/* PyFunctionFastCall */
#if CYTHON_FAST_PYCALL
static PyObject* __Pyx_PyFunction_FastCallNoKw(PyCodeObject *co, PyObject **args, Py_ssize_t na,
                                               PyObject *globals) {
    PyFrameObject *f;
    PyThreadState *tstate = __Pyx_PyThreadState_Current;
    PyObject **fastlocals;
    Py_ssize_t i;
    PyObject *result;
    assert(globals != NULL);
    /* XXX Perhaps we should create a specialized
       PyFrame_New() that doesn't take locals, but does
       take builtins without sanity checking them.
       */
    assert(tstate != NULL);
    f = PyFrame_New(tstate, co, globals, NULL);
    if (f == NULL) {
        return NULL;
    }
    fastlocals = __Pyx_PyFrame_GetLocalsplus(f);
    for (i = 0; i < na; i++) {
        Py_INCREF(*args);
        fastlocals[i] = *args++;
    }
    result = PyEval_EvalFrameEx(f,0);
    ++tstate->recursion_depth;
    Py_DECREF(f);
    --tstate->recursion_depth;
    return result;
}
#if 1 || PY_VERSION_HEX < 0x030600B1
static PyObject *__Pyx_PyFunction_FastCallDict(PyObject *func, PyObject **args, Py_ssize_t nargs, PyObject *kwargs) {
    PyCodeObject *co = (PyCodeObject *)PyFunction_GET_CODE(func);
    PyObject *globals = PyFunction_GET_GLOBALS(func);
    PyObject *argdefs = PyFunction_GET_DEFAULTS(func);
    PyObject *closure;
#if PY_MAJOR_VERSION >= 3
    PyObject *kwdefs;
#endif
    PyObject *kwtuple, **k;
    PyObject **d;
    Py_ssize_t nd;
    Py_ssize_t nk;
    PyObject *result;
    assert(kwargs == NULL || PyDict_Check(kwargs));
    nk = kwargs ? PyDict_Size(kwargs) : 0;
    if (Py_EnterRecursiveCall((char*)" while calling a Python object")) {
        return NULL;
    }
    if (
#if PY_MAJOR_VERSION >= 3
            co->co_kwonlyargcount == 0 &&
#endif
            likely(kwargs == NULL || nk == 0) &&
            co->co_flags == (CO_OPTIMIZED | CO_NEWLOCALS | CO_NOFREE)) {
        if (argdefs == NULL && co->co_argcount == nargs) {
            result = __Pyx_PyFunction_FastCallNoKw(co, args, nargs, globals);
            goto done;
        }
        else if (nargs == 0 && argdefs != NULL
                 && co->co_argcount == Py_SIZE(argdefs)) {
            /* function called with no arguments, but all parameters have
               a default value: use default values as arguments .*/
            args = &PyTuple_GET_ITEM(argdefs, 0);
            result =__Pyx_PyFunction_FastCallNoKw(co, args, Py_SIZE(argdefs), globals);
            goto done;
        }
    }
    if (kwargs != NULL) {
        Py_ssize_t pos, i;
        kwtuple = PyTuple_New(2 * nk);
        if (kwtuple == NULL) {
            result = NULL;
            goto done;
        }
        k = &PyTuple_GET_ITEM(kwtuple, 0);
        pos = i = 0;
        while (PyDict_Next(kwargs, &pos, &k[i], &k[i+1])) {
            Py_INCREF(k[i]);
            Py_INCREF(k[i+1]);
            i += 2;
        }
        nk = i / 2;
    }
    else {
        kwtuple = NULL;
        k = NULL;
    }
    closure = PyFunction_GET_CLOSURE(func);
#if PY_MAJOR_VERSION >= 3
    kwdefs = PyFunction_GET_KW_DEFAULTS(func);
#endif
    if (argdefs != NULL) {
        d = &PyTuple_GET_ITEM(argdefs, 0);
        nd = Py_SIZE(argdefs);
    }
    else {
        d = NULL;
        nd = 0;
    }
#if PY_MAJOR_VERSION >= 3
    result = PyEval_EvalCodeEx((PyObject*)co, globals, (PyObject *)NULL,
                               args, (int)nargs,
                               k, (int)nk,
                               d, (int)nd, kwdefs, closure);
#else
    result = PyEval_EvalCodeEx(co, globals, (PyObject *)NULL,
                               args, (int)nargs,
                               k, (int)nk,
                               d, (int)nd, closure);
#endif
    Py_XDECREF(kwtuple);
done:
    Py_LeaveRecursiveCall();
    return result;
}
#endif
#endif

/* PyCFunctionFastCall */
#if CYTHON_FAST_PYCCALL
static CYTHON_INLINE PyObject * __Pyx_PyCFunction_FastCall(PyObject *func_obj, PyObject **args, Py_ssize_t nargs) {
    PyCFunctionObject *func = (PyCFunctionObject*)func_obj;
    PyCFunction meth = PyCFunction_GET_FUNCTION(func);
    PyObject *self = PyCFunction_GET_SELF(func);
    int flags = PyCFunction_GET_FLAGS(func);
    assert(PyCFunction_Check(func));
    assert(METH_FASTCALL == (flags & ~(METH_CLASS | METH_STATIC | METH_COEXIST | METH_KEYWORDS | METH_STACKLESS)));
    assert(nargs >= 0);
    assert(nargs == 0 || args != NULL);
    /* _PyCFunction_FastCallDict() must not be called with an exception set,
       because it may clear it (directly or indirectly) and so the
       caller loses its exception */
    assert(!PyErr_Occurred());
    if ((PY_VERSION_HEX < 0x030700A0) || unlikely(flags & METH_KEYWORDS)) {
        return (*((__Pyx_PyCFunctionFastWithKeywords)(void*)meth)) (self, args, nargs, NULL);
    } else {
        return (*((__Pyx_PyCFunctionFast)(void*)meth)) (self, args, nargs);
    }
}
#endif

/* PyObjectCall */
#if CYTHON_COMPILING_IN_CPYTHON
static CYTHON_INLINE PyObject* __Pyx_PyObject_Call(PyObject *func, PyObject *arg, PyObject *kw) {
    PyObject *result;
    ternaryfunc call = func->ob_type->tp_call;
    if (unlikely(!call))
        return PyObject_Call(func, arg, kw);
    if (unlikely(Py_EnterRecursiveCall((char*)" while calling a Python object")))
        return NULL;
    result = (*call)(func, arg, kw);
    Py_LeaveRecursiveCall();
    if (unlikely(!result) && unlikely(!PyErr_Occurred())) {
        PyErr_SetString(
            PyExc_SystemError,
            "NULL result without error in PyObject_Call");
    }
    return result;
}
#endif

/* PyDictVersioning */
#if CYTHON_USE_DICT_VERSIONS && CYTHON_USE_TYPE_SLOTS
static CYTHON_INLINE PY_UINT64_T __Pyx_get_tp_dict_version(PyObject *obj) {
    PyObject *dict = Py_TYPE(obj)->tp_dict;
    return likely(dict) ? __PYX_GET_DICT_VERSION(dict) : 0;
}
static CYTHON_INLINE PY_UINT64_T __Pyx_get_object_dict_version(PyObject *obj) {
    PyObject **dictptr = NULL;
    Py_ssize_t offset = Py_TYPE(obj)->tp_dictoffset;
    if (offset) {
#if CYTHON_COMPILING_IN_CPYTHON
        dictptr = (likely(offset > 0)) ? (PyObject **) ((char *)obj + offset) : _PyObject_GetDictPtr(obj);
#else
        dictptr = _PyObject_GetDictPtr(obj);
#endif
    }
    return (dictptr && *dictptr) ? __PYX_GET_DICT_VERSION(*dictptr) : 0;
}
static CYTHON_INLINE int __Pyx_object_dict_version_matches(PyObject* obj, PY_UINT64_T tp_dict_version, PY_UINT64_T obj_dict_version) {
    PyObject *dict = Py_TYPE(obj)->tp_dict;
    if (unlikely(!dict) || unlikely(tp_dict_version != __PYX_GET_DICT_VERSION(dict)))
        return 0;
    return obj_dict_version == __Pyx_get_object_dict_version(obj);
}
#endif

/* PyObjectCallMethO */
#if CYTHON_COMPILING_IN_CPYTHON
static CYTHON_INLINE PyObject* __Pyx_PyObject_CallMethO(PyObject *func, PyObject *arg) {
    PyObject *self, *result;
    PyCFunction cfunc;
    cfunc = PyCFunction_GET_FUNCTION(func);
    self = PyCFunction_GET_SELF(func);
    if (unlikely(Py_EnterRecursiveCall((char*)" while calling a Python object")))
        return NULL;
    result = cfunc(self, arg);
    Py_LeaveRecursiveCall();
    if (unlikely(!result) && unlikely(!PyErr_Occurred())) {
        PyErr_SetString(
            PyExc_SystemError,
            "NULL result without error in PyObject_Call");
    }
    return result;
}
#endif

/* PyObjectCallNoArg */
#if CYTHON_COMPILING_IN_CPYTHON
static CYTHON_INLINE PyObject* __Pyx_PyObject_CallNoArg(PyObject *func) {
#if CYTHON_FAST_PYCALL
    if (PyFunction_Check(func)) {
        return __Pyx_PyFunction_FastCall(func, NULL, 0);
    }
#endif
#ifdef __Pyx_CyFunction_USED
    if (likely(PyCFunction_Check(func) || __Pyx_CyFunction_Check(func)))
#else
    if (likely(PyCFunction_Check(func)))
#endif
    {
        if (likely(PyCFunction_GET_FLAGS(func) & METH_NOARGS)) {
            return __Pyx_PyObject_CallMethO(func, NULL);
        }
    }
    return __Pyx_PyObject_Call(func, __pyx_empty_tuple, NULL);
}
#endif

/* PyObjectCallOneArg */
#if CYTHON_COMPILING_IN_CPYTHON
static PyObject* __Pyx__PyObject_CallOneArg(PyObject *func, PyObject *arg) {
    PyObject *result;
    PyObject *args = PyTuple_New(1);
    if (unlikely(!args)) return NULL;
    Py_INCREF(arg);
    PyTuple_SET_ITEM(args, 0, arg);
    result = __Pyx_PyObject_Call(func, args, NULL);
    Py_DECREF(args);
    return result;
}
static CYTHON_INLINE PyObject* __Pyx_PyObject_CallOneArg(PyObject *func, PyObject *arg) {
#if CYTHON_FAST_PYCALL
    if (PyFunction_Check(func)) {
        return __Pyx_PyFunction_FastCall(func, &arg, 1);
    }
#endif
    if (likely(PyCFunction_Check(func))) {
        if (likely(PyCFunction_GET_FLAGS(func) & METH_O)) {
            return __Pyx_PyObject_CallMethO(func, arg);
#if CYTHON_FAST_PYCCALL
        } else if (PyCFunction_GET_FLAGS(func) & METH_FASTCALL) {
            return __Pyx_PyCFunction_FastCall(func, &arg, 1);
#endif
        }
    }
    return __Pyx__PyObject_CallOneArg(func, arg);
}
#else
static CYTHON_INLINE PyObject* __Pyx_PyObject_CallOneArg(PyObject *func, PyObject *arg) {
    PyObject *result;
    PyObject *args = PyTuple_Pack(1, arg);
    if (unlikely(!args)) return NULL;
    result = __Pyx_PyObject_Call(func, args, NULL);
    Py_DECREF(args);
    return result;
}
#endif

/* GetItemInt */
static PyObject *__Pyx_GetItemInt_Generic(PyObject *o, PyObject* j) {
    PyObject *r;
    if (!j) return NULL;
    r = PyObject_GetItem(o, j);
    Py_DECREF(j);
    return r;
}
static CYTHON_INLINE PyObject *__Pyx_GetItemInt_List_Fast(PyObject *o, Py_ssize_t i,
                                                              CYTHON_NCP_UNUSED int wraparound,
                                                              CYTHON_NCP_UNUSED int boundscheck) {
#if CYTHON_ASSUME_SAFE_MACROS && !CYTHON_AVOID_BORROWED_REFS
    Py_ssize_t wrapped_i = i;
    if (wraparound & unlikely(i < 0)) {
        wrapped_i += PyList_GET_SIZE(o);
    }
    if ((!boundscheck) || likely(__Pyx_is_valid_index(wrapped_i, PyList_GET_SIZE(o)))) {
        PyObject *r = PyList_GET_ITEM(o, wrapped_i);
        Py_INCREF(r);
        return r;
    }
    return __Pyx_GetItemInt_Generic(o, PyInt_FromSsize_t(i));
#else
    return PySequence_GetItem(o, i);
#endif
}
static CYTHON_INLINE PyObject *__Pyx_GetItemInt_Tuple_Fast(PyObject *o, Py_ssize_t i,
                                                              CYTHON_NCP_UNUSED int wraparound,
                                                              CYTHON_NCP_UNUSED int boundscheck) {
#if CYTHON_ASSUME_SAFE_MACROS && !CYTHON_AVOID_BORROWED_REFS
    Py_ssize_t wrapped_i = i;
    if (wraparound & unlikely(i < 0)) {
        wrapped_i += PyTuple_GET_SIZE(o);
    }
    if ((!boundscheck) || likely(__Pyx_is_valid_index(wrapped_i, PyTuple_GET_SIZE(o)))) {
        PyObject *r = PyTuple_GET_ITEM(o, wrapped_i);
        Py_INCREF(r);
        return r;
    }
    return __Pyx_GetItemInt_Generic(o, PyInt_FromSsize_t(i));
#else
    return PySequence_GetItem(o, i);
#endif
}
static CYTHON_INLINE PyObject *__Pyx_GetItemInt_Fast(PyObject *o, Py_ssize_t i, int is_list,
                                                     CYTHON_NCP_UNUSED int wraparound,
                                                     CYTHON_NCP_UNUSED int boundscheck) {
#if CYTHON_ASSUME_SAFE_MACROS && !CYTHON_AVOID_BORROWED_REFS && CYTHON_USE_TYPE_SLOTS
    if (is_list || PyList_CheckExact(o)) {
        Py_ssize_t n = ((!wraparound) | likely(i >= 0)) ? i : i + PyList_GET_SIZE(o);
        if ((!boundscheck) || (likely(__Pyx_is_valid_index(n, PyList_GET_SIZE(o))))) {
            PyObject *r = PyList_GET_ITEM(o, n);
            Py_INCREF(r);
            return r;
        }
    }
    else if (PyTuple_CheckExact(o)) {
        Py_ssize_t n = ((!wraparound) | likely(i >= 0)) ? i : i + PyTuple_GET_SIZE(o);
        if ((!boundscheck) || likely(__Pyx_is_valid_index(n, PyTuple_GET_SIZE(o)))) {
            PyObject *r = PyTuple_GET_ITEM(o, n);
            Py_INCREF(r);
            return r;
        }
    } else {
        PySequenceMethods *m = Py_TYPE(o)->tp_as_sequence;
        if (likely(m && m->sq_item)) {
            if (wraparound && unlikely(i < 0) && likely(m->sq_length)) {
                Py_ssize_t l = m->sq_length(o);
                if (likely(l >= 0)) {
                    i += l;
                } else {
                    if (!PyErr_ExceptionMatches(PyExc_OverflowError))
                        return NULL;
                    PyErr_Clear();
                }
            }
            return m->sq_item(o, i);
        }
    }
#else
    if (is_list || PySequence_Check(o)) {
        return PySequence_GetItem(o, i);
    }
#endif
    return __Pyx_GetItemInt_Generic(o, PyInt_FromSsize_t(i));
}

/* PyErrFetchRestore */
#if CYTHON_FAST_THREAD_STATE
static CYTHON_INLINE void __Pyx_ErrRestoreInState(PyThreadState *tstate, PyObject *type, PyObject *value, PyObject *tb) {
    PyObject *tmp_type, *tmp_value, *tmp_tb;
    tmp_type = tstate->curexc_type;
    tmp_value = tstate->curexc_value;
    tmp_tb = tstate->curexc_traceback;
    tstate->curexc_type = type;
    tstate->curexc_value = value;
    tstate->curexc_traceback = tb;
    Py_XDECREF(tmp_type);
    Py_XDECREF(tmp_value);
    Py_XDECREF(tmp_tb);
}
static CYTHON_INLINE void __Pyx_ErrFetchInState(PyThreadState *tstate, PyObject **type, PyObject **value, PyObject **tb) {
    *type = tstate->curexc_type;
    *value = tstate->curexc_value;
    *tb = tstate->curexc_traceback;
    tstate->curexc_type = 0;
    tstate->curexc_value = 0;
    tstate->curexc_traceback = 0;
}
#endif

/* WriteUnraisableException */
static void __Pyx_WriteUnraisable(const char *name, CYTHON_UNUSED int clineno,
                                  CYTHON_UNUSED int lineno, CYTHON_UNUSED const char *filename,
                                  int full_traceback, CYTHON_UNUSED int nogil) {
    PyObject *old_exc, *old_val, *old_tb;
    PyObject *ctx;
    __Pyx_PyThreadState_declare
#ifdef WITH_THREAD
    PyGILState_STATE state;
    if (nogil)
        state = PyGILState_Ensure();
#ifdef _MSC_VER
    else state = (PyGILState_STATE)-1;
#endif
#endif
    __Pyx_PyThreadState_assign
    __Pyx_ErrFetch(&old_exc, &old_val, &old_tb);
    if (full_traceback) {
        Py_XINCREF(old_exc);
        Py_XINCREF(old_val);
        Py_XINCREF(old_tb);
        __Pyx_ErrRestore(old_exc, old_val, old_tb);
        PyErr_PrintEx(1);
    }
    #if PY_MAJOR_VERSION < 3
    ctx = PyString_FromString(name);
    #else
    ctx = PyUnicode_FromString(name);
    #endif
    __Pyx_ErrRestore(old_exc, old_val, old_tb);
    if (!ctx) {
        PyErr_WriteUnraisable(Py_None);
    } else {
        PyErr_WriteUnraisable(ctx);
        Py_DECREF(ctx);
    }
#ifdef WITH_THREAD
    if (nogil)
        PyGILState_Release(state);
#endif
}

/* PyIntBinop */
#if !CYTHON_COMPILING_IN_PYPY
static PyObject* __Pyx_PyInt_AddObjC(PyObject *op1, PyObject *op2, CYTHON_UNUSED long intval, int inplace, int zerodivision_check) {
    (void)inplace;
    (void)zerodivision_check;
    #if PY_MAJOR_VERSION < 3
    if (likely(PyInt_CheckExact(op1))) {
        const long b = intval;
        long x;
        long a = PyInt_AS_LONG(op1);
            x = (long)((unsigned long)a + b);
            if (likely((x^a) >= 0 || (x^b) >= 0))
                return PyInt_FromLong(x);
            return PyLong_Type.tp_as_number->nb_add(op1, op2);
    }
    #endif
    #if CYTHON_USE_PYLONG_INTERNALS
    if (likely(PyLong_CheckExact(op1))) {
        const long b = intval;
        long a, x;
#ifdef HAVE_LONG_LONG
        const PY_LONG_LONG llb = intval;
        PY_LONG_LONG lla, llx;
#endif
        const digit* digits = ((PyLongObject*)op1)->ob_digit;
        const Py_ssize_t size = Py_SIZE(op1);
        if (likely(__Pyx_sst_abs(size) <= 1)) {
            a = likely(size) ? digits[0] : 0;
            if (size == -1) a = -a;
        } else {
            switch (size) {
                case -2:
                    if (8 * sizeof(long) - 1 > 2 * PyLong_SHIFT) {
                        a = -(long) (((((unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0]));
                        break;
#ifdef HAVE_LONG_LONG
                    } else if (8 * sizeof(PY_LONG_LONG) - 1 > 2 * PyLong_SHIFT) {
                        lla = -(PY_LONG_LONG) (((((unsigned PY_LONG_LONG)digits[1]) << PyLong_SHIFT) | (unsigned PY_LONG_LONG)digits[0]));
                        goto long_long;
#endif
                    }
                    CYTHON_FALLTHROUGH;
                case 2:
                    if (8 * sizeof(long) - 1 > 2 * PyLong_SHIFT) {
                        a = (long) (((((unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0]));
                        break;
#ifdef HAVE_LONG_LONG
                    } else if (8 * sizeof(PY_LONG_LONG) - 1 > 2 * PyLong_SHIFT) {
                        lla = (PY_LONG_LONG) (((((unsigned PY_LONG_LONG)digits[1]) << PyLong_SHIFT) | (unsigned PY_LONG_LONG)digits[0]));
                        goto long_long;
#endif
                    }
                    CYTHON_FALLTHROUGH;
                case -3:
                    if (8 * sizeof(long) - 1 > 3 * PyLong_SHIFT) {
                        a = -(long) (((((((unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0]));
                        break;
#ifdef HAVE_LONG_LONG
                    } else if (8 * sizeof(PY_LONG_LONG) - 1 > 3 * PyLong_SHIFT) {
                        lla = -(PY_LONG_LONG) (((((((unsigned PY_LONG_LONG)digits[2]) << PyLong_SHIFT) | (unsigned PY_LONG_LONG)digits[1]) << PyLong_SHIFT) | (unsigned PY_LONG_LONG)digits[0]));
                        goto long_long;
#endif
                    }
                    CYTHON_FALLTHROUGH;
                case 3:
                    if (8 * sizeof(long) - 1 > 3 * PyLong_SHIFT) {
                        a = (long) (((((((unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0]));
                        break;
#ifdef HAVE_LONG_LONG
                    } else if (8 * sizeof(PY_LONG_LONG) - 1 > 3 * PyLong_SHIFT) {
                        lla = (PY_LONG_LONG) (((((((unsigned PY_LONG_LONG)digits[2]) << PyLong_SHIFT) | (unsigned PY_LONG_LONG)digits[1]) << PyLong_SHIFT) | (unsigned PY_LONG_LONG)digits[0]));
                        goto long_long;
#endif
                    }
                    CYTHON_FALLTHROUGH;
                case -4:
                    if (8 * sizeof(long) - 1 > 4 * PyLong_SHIFT) {
                        a = -(long) (((((((((unsigned long)digits[3]) << PyLong_SHIFT) | (unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0]));
                        break;
#ifdef HAVE_LONG_LONG
                    } else if (8 * sizeof(PY_LONG_LONG) - 1 > 4 * PyLong_SHIFT) {
                        lla = -(PY_LONG_LONG) (((((((((unsigned PY_LONG_LONG)digits[3]) << PyLong_SHIFT) | (unsigned PY_LONG_LONG)digits[2]) << PyLong_SHIFT) | (unsigned PY_LONG_LONG)digits[1]) << PyLong_SHIFT) | (unsigned PY_LONG_LONG)digits[0]));
                        goto long_long;
#endif
                    }
                    CYTHON_FALLTHROUGH;
                case 4:
                    if (8 * sizeof(long) - 1 > 4 * PyLong_SHIFT) {
                        a = (long) (((((((((unsigned long)digits[3]) << PyLong_SHIFT) | (unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0]));
                        break;
#ifdef HAVE_LONG_LONG
                    } else if (8 * sizeof(PY_LONG_LONG) - 1 > 4 * PyLong_SHIFT) {
                        lla = (PY_LONG_LONG) (((((((((unsigned PY_LONG_LONG)digits[3]) << PyLong_SHIFT) | (unsigned PY_LONG_LONG)digits[2]) << PyLong_SHIFT) | (unsigned PY_LONG_LONG)digits[1]) << PyLong_SHIFT) | (unsigned PY_LONG_LONG)digits[0]));
                        goto long_long;
#endif
                    }
                    CYTHON_FALLTHROUGH;
                default: return PyLong_Type.tp_as_number->nb_add(op1, op2);
            }
        }
                x = a + b;
            return PyLong_FromLong(x);
#ifdef HAVE_LONG_LONG
        long_long:
                llx = lla + llb;
            return PyLong_FromLongLong(llx);
#endif
        
        
    }
    #endif
    if (PyFloat_CheckExact(op1)) {
        const long b = intval;
        double a = PyFloat_AS_DOUBLE(op1);
            double result;
            PyFPE_START_PROTECT("add", return NULL)
            result = ((double)a) + (double)b;
            PyFPE_END_PROTECT(result)
            return PyFloat_FromDouble(result);
    }
    return (inplace ? PyNumber_InPlaceAdd : PyNumber_Add)(op1, op2);
}
#endif

/* ObjectGetItem */
#if CYTHON_USE_TYPE_SLOTS
static PyObject *__Pyx_PyObject_GetIndex(PyObject *obj, PyObject* index) {
    PyObject *runerr;
    Py_ssize_t key_value;
    PySequenceMethods *m = Py_TYPE(obj)->tp_as_sequence;
    if (unlikely(!(m && m->sq_item))) {
        PyErr_Format(PyExc_TypeError, "'%.200s' object is not subscriptable", Py_TYPE(obj)->tp_name);
        return NULL;
    }
    key_value = __Pyx_PyIndex_AsSsize_t(index);
    if (likely(key_value != -1 || !(runerr = PyErr_Occurred()))) {
        return __Pyx_GetItemInt_Fast(obj, key_value, 0, 1, 1);
    }
    if (PyErr_GivenExceptionMatches(runerr, PyExc_OverflowError)) {
        PyErr_Clear();
        PyErr_Format(PyExc_IndexError, "cannot fit '%.200s' into an index-sized integer", Py_TYPE(index)->tp_name);
    }
    return NULL;
}
static PyObject *__Pyx_PyObject_GetItem(PyObject *obj, PyObject* key) {
    PyMappingMethods *m = Py_TYPE(obj)->tp_as_mapping;
    if (likely(m && m->mp_subscript)) {
        return m->mp_subscript(obj, key);
    }
    return __Pyx_PyObject_GetIndex(obj, key);
}
#endif

/* PyObjectCall2Args */
static CYTHON_UNUSED PyObject* __Pyx_PyObject_Call2Args(PyObject* function, PyObject* arg1, PyObject* arg2) {
    PyObject *args, *result = NULL;
    #if CYTHON_FAST_PYCALL
    if (PyFunction_Check(function)) {
        PyObject *args[2] = {arg1, arg2};
        return __Pyx_PyFunction_FastCall(function, args, 2);
    }
    #endif
    #if CYTHON_FAST_PYCCALL
    if (__Pyx_PyFastCFunction_Check(function)) {
        PyObject *args[2] = {arg1, arg2};
        return __Pyx_PyCFunction_FastCall(function, args, 2);
    }
    #endif
    args = PyTuple_New(2);
    if (unlikely(!args)) goto done;
    Py_INCREF(arg1);
    PyTuple_SET_ITEM(args, 0, arg1);
    Py_INCREF(arg2);
    PyTuple_SET_ITEM(args, 1, arg2);
    Py_INCREF(function);
    result = __Pyx_PyObject_Call(function, args, NULL);
    Py_DECREF(args);
    Py_DECREF(function);
done:
    return result;
}

/* py_abs */
#if CYTHON_USE_PYLONG_INTERNALS
static PyObject *__Pyx_PyLong_AbsNeg(PyObject *n) {
    if (likely(Py_SIZE(n) == -1)) {
        return PyLong_FromLong(((PyLongObject*)n)->ob_digit[0]);
    }
#if CYTHON_COMPILING_IN_CPYTHON
    {
        PyObject *copy = _PyLong_Copy((PyLongObject*)n);
        if (likely(copy)) {
            Py_SIZE(copy) = -(Py_SIZE(copy));
        }
        return copy;
    }
#else
    return PyNumber_Negative(n);
#endif
}
#endif

/* ArgTypeTest */
static int __Pyx__ArgTypeTest(PyObject *obj, PyTypeObject *type, const char *name, int exact)
{
    if (unlikely(!type)) {
        PyErr_SetString(PyExc_SystemError, "Missing type object");
        return 0;
    }
    else if (exact) {
        #if PY_MAJOR_VERSION == 2
        if ((type == &PyBaseString_Type) && likely(__Pyx_PyBaseString_CheckExact(obj))) return 1;
        #endif
    }
    else {
        if (likely(__Pyx_TypeCheck(obj, type))) return 1;
    }
    PyErr_Format(PyExc_TypeError,
        "Argument '%.200s' has incorrect type (expected %.200s, got %.200s)",
        name, type->tp_name, Py_TYPE(obj)->tp_name);
    return 0;
}

/* BytesEquals */
static CYTHON_INLINE int __Pyx_PyBytes_Equals(PyObject* s1, PyObject* s2, int equals) {
#if CYTHON_COMPILING_IN_PYPY
    return PyObject_RichCompareBool(s1, s2, equals);
#else
    if (s1 == s2) {
        return (equals == Py_EQ);
    } else if (PyBytes_CheckExact(s1) & PyBytes_CheckExact(s2)) {
        const char *ps1, *ps2;
        Py_ssize_t length = PyBytes_GET_SIZE(s1);
        if (length != PyBytes_GET_SIZE(s2))
            return (equals == Py_NE);
        ps1 = PyBytes_AS_STRING(s1);
        ps2 = PyBytes_AS_STRING(s2);
        if (ps1[0] != ps2[0]) {
            return (equals == Py_NE);
        } else if (length == 1) {
            return (equals == Py_EQ);
        } else {
            int result;
#if CYTHON_USE_UNICODE_INTERNALS
            Py_hash_t hash1, hash2;
            hash1 = ((PyBytesObject*)s1)->ob_shash;
            hash2 = ((PyBytesObject*)s2)->ob_shash;
            if (hash1 != hash2 && hash1 != -1 && hash2 != -1) {
                return (equals == Py_NE);
            }
#endif
            result = memcmp(ps1, ps2, (size_t)length);
            return (equals == Py_EQ) ? (result == 0) : (result != 0);
        }
    } else if ((s1 == Py_None) & PyBytes_CheckExact(s2)) {
        return (equals == Py_NE);
    } else if ((s2 == Py_None) & PyBytes_CheckExact(s1)) {
        return (equals == Py_NE);
    } else {
        int result;
        PyObject* py_result = PyObject_RichCompare(s1, s2, equals);
        if (!py_result)
            return -1;
        result = __Pyx_PyObject_IsTrue(py_result);
        Py_DECREF(py_result);
        return result;
    }
#endif
}

/* UnicodeEquals */
static CYTHON_INLINE int __Pyx_PyUnicode_Equals(PyObject* s1, PyObject* s2, int equals) {
#if CYTHON_COMPILING_IN_PYPY
    return PyObject_RichCompareBool(s1, s2, equals);
#else
#if PY_MAJOR_VERSION < 3
    PyObject* owned_ref = NULL;
#endif
    int s1_is_unicode, s2_is_unicode;
    if (s1 == s2) {
        goto return_eq;
    }
    s1_is_unicode = PyUnicode_CheckExact(s1);
    s2_is_unicode = PyUnicode_CheckExact(s2);
#if PY_MAJOR_VERSION < 3
    if ((s1_is_unicode & (!s2_is_unicode)) && PyString_CheckExact(s2)) {
        owned_ref = PyUnicode_FromObject(s2);
        if (unlikely(!owned_ref))
            return -1;
        s2 = owned_ref;
        s2_is_unicode = 1;
    } else if ((s2_is_unicode & (!s1_is_unicode)) && PyString_CheckExact(s1)) {
        owned_ref = PyUnicode_FromObject(s1);
        if (unlikely(!owned_ref))
            return -1;
        s1 = owned_ref;
        s1_is_unicode = 1;
    } else if (((!s2_is_unicode) & (!s1_is_unicode))) {
        return __Pyx_PyBytes_Equals(s1, s2, equals);
    }
#endif
    if (s1_is_unicode & s2_is_unicode) {
        Py_ssize_t length;
        int kind;
        void *data1, *data2;
        if (unlikely(__Pyx_PyUnicode_READY(s1) < 0) || unlikely(__Pyx_PyUnicode_READY(s2) < 0))
            return -1;
        length = __Pyx_PyUnicode_GET_LENGTH(s1);
        if (length != __Pyx_PyUnicode_GET_LENGTH(s2)) {
            goto return_ne;
        }
#if CYTHON_USE_UNICODE_INTERNALS
        {
            Py_hash_t hash1, hash2;
        #if CYTHON_PEP393_ENABLED
            hash1 = ((PyASCIIObject*)s1)->hash;
            hash2 = ((PyASCIIObject*)s2)->hash;
        #else
            hash1 = ((PyUnicodeObject*)s1)->hash;
            hash2 = ((PyUnicodeObject*)s2)->hash;
        #endif
            if (hash1 != hash2 && hash1 != -1 && hash2 != -1) {
                goto return_ne;
            }
        }
#endif
        kind = __Pyx_PyUnicode_KIND(s1);
        if (kind != __Pyx_PyUnicode_KIND(s2)) {
            goto return_ne;
        }
        data1 = __Pyx_PyUnicode_DATA(s1);
        data2 = __Pyx_PyUnicode_DATA(s2);
        if (__Pyx_PyUnicode_READ(kind, data1, 0) != __Pyx_PyUnicode_READ(kind, data2, 0)) {
            goto return_ne;
        } else if (length == 1) {
            goto return_eq;
        } else {
            int result = memcmp(data1, data2, (size_t)(length * kind));
            #if PY_MAJOR_VERSION < 3
            Py_XDECREF(owned_ref);
            #endif
            return (equals == Py_EQ) ? (result == 0) : (result != 0);
        }
    } else if ((s1 == Py_None) & s2_is_unicode) {
        goto return_ne;
    } else if ((s2 == Py_None) & s1_is_unicode) {
        goto return_ne;
    } else {
        int result;
        PyObject* py_result = PyObject_RichCompare(s1, s2, equals);
        #if PY_MAJOR_VERSION < 3
        Py_XDECREF(owned_ref);
        #endif
        if (!py_result)
            return -1;
        result = __Pyx_PyObject_IsTrue(py_result);
        Py_DECREF(py_result);
        return result;
    }
return_eq:
    #if PY_MAJOR_VERSION < 3
    Py_XDECREF(owned_ref);
    #endif
    return (equals == Py_EQ);
return_ne:
    #if PY_MAJOR_VERSION < 3
    Py_XDECREF(owned_ref);
    #endif
    return (equals == Py_NE);
#endif
}

/* GetModuleGlobalName */
#if CYTHON_USE_DICT_VERSIONS
static PyObject *__Pyx__GetModuleGlobalName(PyObject *name, PY_UINT64_T *dict_version, PyObject **dict_cached_value)
#else
static CYTHON_INLINE PyObject *__Pyx__GetModuleGlobalName(PyObject *name)
#endif
{
    PyObject *result;
#if !CYTHON_AVOID_BORROWED_REFS
#if CYTHON_COMPILING_IN_CPYTHON && PY_VERSION_HEX >= 0x030500A1
    result = _PyDict_GetItem_KnownHash(__pyx_d, name, ((PyASCIIObject *) name)->hash);
    __PYX_UPDATE_DICT_CACHE(__pyx_d, result, *dict_cached_value, *dict_version)
    if (likely(result)) {
        return __Pyx_NewRef(result);
    } else if (unlikely(PyErr_Occurred())) {
        return NULL;
    }
#else
    result = PyDict_GetItem(__pyx_d, name);
    __PYX_UPDATE_DICT_CACHE(__pyx_d, result, *dict_cached_value, *dict_version)
    if (likely(result)) {
        return __Pyx_NewRef(result);
    }
#endif
#else
    result = PyObject_GetItem(__pyx_d, name);
    __PYX_UPDATE_DICT_CACHE(__pyx_d, result, *dict_cached_value, *dict_version)
    if (likely(result)) {
        return __Pyx_NewRef(result);
    }
    PyErr_Clear();
#endif
    return __Pyx_GetBuiltinName(name);
}

/* DictGetItem */
#if PY_MAJOR_VERSION >= 3 && !CYTHON_COMPILING_IN_PYPY
static PyObject *__Pyx_PyDict_GetItem(PyObject *d, PyObject* key) {
    PyObject *value;
    value = PyDict_GetItemWithError(d, key);
    if (unlikely(!value)) {
        if (!PyErr_Occurred()) {
            if (unlikely(PyTuple_Check(key))) {
                PyObject* args = PyTuple_Pack(1, key);
                if (likely(args)) {
                    PyErr_SetObject(PyExc_KeyError, args);
                    Py_DECREF(args);
                }
            } else {
                PyErr_SetObject(PyExc_KeyError, key);
            }
        }
        return NULL;
    }
    Py_INCREF(value);
    return value;
}
#endif

/* UnpackUnboundCMethod */
static int __Pyx_TryUnpackUnboundCMethod(__Pyx_CachedCFunction* target) {
    PyObject *method;
    method = __Pyx_PyObject_GetAttrStr(target->type, *target->method_name);
    if (unlikely(!method))
        return -1;
    target->method = method;
#if CYTHON_COMPILING_IN_CPYTHON
    #if PY_MAJOR_VERSION >= 3
    if (likely(__Pyx_TypeCheck(method, &PyMethodDescr_Type)))
    #endif
    {
        PyMethodDescrObject *descr = (PyMethodDescrObject*) method;
        target->func = descr->d_method->ml_meth;
        target->flag = descr->d_method->ml_flags & ~(METH_CLASS | METH_STATIC | METH_COEXIST | METH_STACKLESS);
    }
#endif
    return 0;
}

/* CallUnboundCMethod1 */
#if CYTHON_COMPILING_IN_CPYTHON
static CYTHON_INLINE PyObject* __Pyx_CallUnboundCMethod1(__Pyx_CachedCFunction* cfunc, PyObject* self, PyObject* arg) {
    if (likely(cfunc->func)) {
        int flag = cfunc->flag;
        if (flag == METH_O) {
            return (*(cfunc->func))(self, arg);
        } else if (PY_VERSION_HEX >= 0x030600B1 && flag == METH_FASTCALL) {
            if (PY_VERSION_HEX >= 0x030700A0) {
                return (*(__Pyx_PyCFunctionFast)(void*)(PyCFunction)cfunc->func)(self, &arg, 1);
            } else {
                return (*(__Pyx_PyCFunctionFastWithKeywords)(void*)(PyCFunction)cfunc->func)(self, &arg, 1, NULL);
            }
        } else if (PY_VERSION_HEX >= 0x030700A0 && flag == (METH_FASTCALL | METH_KEYWORDS)) {
            return (*(__Pyx_PyCFunctionFastWithKeywords)(void*)(PyCFunction)cfunc->func)(self, &arg, 1, NULL);
        }
    }
    return __Pyx__CallUnboundCMethod1(cfunc, self, arg);
}
#endif
static PyObject* __Pyx__CallUnboundCMethod1(__Pyx_CachedCFunction* cfunc, PyObject* self, PyObject* arg){
    PyObject *args, *result = NULL;
    if (unlikely(!cfunc->func && !cfunc->method) && unlikely(__Pyx_TryUnpackUnboundCMethod(cfunc) < 0)) return NULL;
#if CYTHON_COMPILING_IN_CPYTHON
    if (cfunc->func && (cfunc->flag & METH_VARARGS)) {
        args = PyTuple_New(1);
        if (unlikely(!args)) goto bad;
        Py_INCREF(arg);
        PyTuple_SET_ITEM(args, 0, arg);
        if (cfunc->flag & METH_KEYWORDS)
            result = (*(PyCFunctionWithKeywords)(void*)(PyCFunction)cfunc->func)(self, args, NULL);
        else
            result = (*cfunc->func)(self, args);
    } else {
        args = PyTuple_New(2);
        if (unlikely(!args)) goto bad;
        Py_INCREF(self);
        PyTuple_SET_ITEM(args, 0, self);
        Py_INCREF(arg);
        PyTuple_SET_ITEM(args, 1, arg);
        result = __Pyx_PyObject_Call(cfunc->method, args, NULL);
    }
#else
    args = PyTuple_Pack(2, self, arg);
    if (unlikely(!args)) goto bad;
    result = __Pyx_PyObject_Call(cfunc->method, args, NULL);
#endif
bad:
    Py_XDECREF(args);
    return result;
}

/* CallUnboundCMethod2 */
#if CYTHON_COMPILING_IN_CPYTHON && PY_VERSION_HEX >= 0x030600B1
static CYTHON_INLINE PyObject *__Pyx_CallUnboundCMethod2(__Pyx_CachedCFunction *cfunc, PyObject *self, PyObject *arg1, PyObject *arg2) {
    if (likely(cfunc->func)) {
        PyObject *args[2] = {arg1, arg2};
        if (cfunc->flag == METH_FASTCALL) {
            #if PY_VERSION_HEX >= 0x030700A0
            return (*(__Pyx_PyCFunctionFast)(void*)(PyCFunction)cfunc->func)(self, args, 2);
            #else
            return (*(__Pyx_PyCFunctionFastWithKeywords)(void*)(PyCFunction)cfunc->func)(self, args, 2, NULL);
            #endif
        }
        #if PY_VERSION_HEX >= 0x030700A0
        if (cfunc->flag == (METH_FASTCALL | METH_KEYWORDS))
            return (*(__Pyx_PyCFunctionFastWithKeywords)(void*)(PyCFunction)cfunc->func)(self, args, 2, NULL);
        #endif
    }
    return __Pyx__CallUnboundCMethod2(cfunc, self, arg1, arg2);
}
#endif
static PyObject* __Pyx__CallUnboundCMethod2(__Pyx_CachedCFunction* cfunc, PyObject* self, PyObject* arg1, PyObject* arg2){
    PyObject *args, *result = NULL;
    if (unlikely(!cfunc->func && !cfunc->method) && unlikely(__Pyx_TryUnpackUnboundCMethod(cfunc) < 0)) return NULL;
#if CYTHON_COMPILING_IN_CPYTHON
    if (cfunc->func && (cfunc->flag & METH_VARARGS)) {
        args = PyTuple_New(2);
        if (unlikely(!args)) goto bad;
        Py_INCREF(arg1);
        PyTuple_SET_ITEM(args, 0, arg1);
        Py_INCREF(arg2);
        PyTuple_SET_ITEM(args, 1, arg2);
        if (cfunc->flag & METH_KEYWORDS)
            result = (*(PyCFunctionWithKeywords)(void*)(PyCFunction)cfunc->func)(self, args, NULL);
        else
            result = (*cfunc->func)(self, args);
    } else {
        args = PyTuple_New(3);
        if (unlikely(!args)) goto bad;
        Py_INCREF(self);
        PyTuple_SET_ITEM(args, 0, self);
        Py_INCREF(arg1);
        PyTuple_SET_ITEM(args, 1, arg1);
        Py_INCREF(arg2);
        PyTuple_SET_ITEM(args, 2, arg2);
        result = __Pyx_PyObject_Call(cfunc->method, args, NULL);
    }
#else
    args = PyTuple_Pack(3, self, arg1, arg2);
    if (unlikely(!args)) goto bad;
    result = __Pyx_PyObject_Call(cfunc->method, args, NULL);
#endif
bad:
    Py_XDECREF(args);
    return result;
}

/* dict_getitem_default */
static PyObject* __Pyx_PyDict_GetItemDefault(PyObject* d, PyObject* key, PyObject* default_value) {
    PyObject* value;
#if PY_MAJOR_VERSION >= 3 && !CYTHON_COMPILING_IN_PYPY
    value = PyDict_GetItemWithError(d, key);
    if (unlikely(!value)) {
        if (unlikely(PyErr_Occurred()))
            return NULL;
        value = default_value;
    }
    Py_INCREF(value);
    if ((1));
#else
    if (PyString_CheckExact(key) || PyUnicode_CheckExact(key) || PyInt_CheckExact(key)) {
        value = PyDict_GetItem(d, key);
        if (unlikely(!value)) {
            value = default_value;
        }
        Py_INCREF(value);
    }
#endif
    else {
        if (default_value == Py_None)
            value = __Pyx_CallUnboundCMethod1(&__pyx_umethod_PyDict_Type_get, d, key);
        else
            value = __Pyx_CallUnboundCMethod2(&__pyx_umethod_PyDict_Type_get, d, key, default_value);
    }
    return value;
}

/* PyIntBinop */
#if !CYTHON_COMPILING_IN_PYPY
static PyObject* __Pyx_PyInt_SubtractObjC(PyObject *op1, PyObject *op2, CYTHON_UNUSED long intval, int inplace, int zerodivision_check) {
    (void)inplace;
    (void)zerodivision_check;
    #if PY_MAJOR_VERSION < 3
    if (likely(PyInt_CheckExact(op1))) {
        const long b = intval;
        long x;
        long a = PyInt_AS_LONG(op1);
            x = (long)((unsigned long)a - b);
            if (likely((x^a) >= 0 || (x^~b) >= 0))
                return PyInt_FromLong(x);
            return PyLong_Type.tp_as_number->nb_subtract(op1, op2);
    }
    #endif
    #if CYTHON_USE_PYLONG_INTERNALS
    if (likely(PyLong_CheckExact(op1))) {
        const long b = intval;
        long a, x;
#ifdef HAVE_LONG_LONG
        const PY_LONG_LONG llb = intval;
        PY_LONG_LONG lla, llx;
#endif
        const digit* digits = ((PyLongObject*)op1)->ob_digit;
        const Py_ssize_t size = Py_SIZE(op1);
        if (likely(__Pyx_sst_abs(size) <= 1)) {
            a = likely(size) ? digits[0] : 0;
            if (size == -1) a = -a;
        } else {
            switch (size) {
                case -2:
                    if (8 * sizeof(long) - 1 > 2 * PyLong_SHIFT) {
                        a = -(long) (((((unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0]));
                        break;
#ifdef HAVE_LONG_LONG
                    } else if (8 * sizeof(PY_LONG_LONG) - 1 > 2 * PyLong_SHIFT) {
                        lla = -(PY_LONG_LONG) (((((unsigned PY_LONG_LONG)digits[1]) << PyLong_SHIFT) | (unsigned PY_LONG_LONG)digits[0]));
                        goto long_long;
#endif
                    }
                    CYTHON_FALLTHROUGH;
                case 2:
                    if (8 * sizeof(long) - 1 > 2 * PyLong_SHIFT) {
                        a = (long) (((((unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0]));
                        break;
#ifdef HAVE_LONG_LONG
                    } else if (8 * sizeof(PY_LONG_LONG) - 1 > 2 * PyLong_SHIFT) {
                        lla = (PY_LONG_LONG) (((((unsigned PY_LONG_LONG)digits[1]) << PyLong_SHIFT) | (unsigned PY_LONG_LONG)digits[0]));
                        goto long_long;
#endif
                    }
                    CYTHON_FALLTHROUGH;
                case -3:
                    if (8 * sizeof(long) - 1 > 3 * PyLong_SHIFT) {
                        a = -(long) (((((((unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0]));
                        break;
#ifdef HAVE_LONG_LONG
                    } else if (8 * sizeof(PY_LONG_LONG) - 1 > 3 * PyLong_SHIFT) {
                        lla = -(PY_LONG_LONG) (((((((unsigned PY_LONG_LONG)digits[2]) << PyLong_SHIFT) | (unsigned PY_LONG_LONG)digits[1]) << PyLong_SHIFT) | (unsigned PY_LONG_LONG)digits[0]));
                        goto long_long;
#endif
                    }
                    CYTHON_FALLTHROUGH;
                case 3:
                    if (8 * sizeof(long) - 1 > 3 * PyLong_SHIFT) {
                        a = (long) (((((((unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0]));
                        break;
#ifdef HAVE_LONG_LONG
                    } else if (8 * sizeof(PY_LONG_LONG) - 1 > 3 * PyLong_SHIFT) {
                        lla = (PY_LONG_LONG) (((((((unsigned PY_LONG_LONG)digits[2]) << PyLong_SHIFT) | (unsigned PY_LONG_LONG)digits[1]) << PyLong_SHIFT) | (unsigned PY_LONG_LONG)digits[0]));
                        goto long_long;
#endif
                    }
                    CYTHON_FALLTHROUGH;
                case -4:
                    if (8 * sizeof(long) - 1 > 4 * PyLong_SHIFT) {
                        a = -(long) (((((((((unsigned long)digits[3]) << PyLong_SHIFT) | (unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0]));
                        break;
#ifdef HAVE_LONG_LONG
                    } else if (8 * sizeof(PY_LONG_LONG) - 1 > 4 * PyLong_SHIFT) {
                        lla = -(PY_LONG_LONG) (((((((((unsigned PY_LONG_LONG)digits[3]) << PyLong_SHIFT) | (unsigned PY_LONG_LONG)digits[2]) << PyLong_SHIFT) | (unsigned PY_LONG_LONG)digits[1]) << PyLong_SHIFT) | (unsigned PY_LONG_LONG)digits[0]));
                        goto long_long;
#endif
                    }
                    CYTHON_FALLTHROUGH;
                case 4:
                    if (8 * sizeof(long) - 1 > 4 * PyLong_SHIFT) {
                        a = (long) (((((((((unsigned long)digits[3]) << PyLong_SHIFT) | (unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0]));
                        break;
#ifdef HAVE_LONG_LONG
                    } else if (8 * sizeof(PY_LONG_LONG) - 1 > 4 * PyLong_SHIFT) {
                        lla = (PY_LONG_LONG) (((((((((unsigned PY_LONG_LONG)digits[3]) << PyLong_SHIFT) | (unsigned PY_LONG_LONG)digits[2]) << PyLong_SHIFT) | (unsigned PY_LONG_LONG)digits[1]) << PyLong_SHIFT) | (unsigned PY_LONG_LONG)digits[0]));
                        goto long_long;
#endif
                    }
                    CYTHON_FALLTHROUGH;
                default: return PyLong_Type.tp_as_number->nb_subtract(op1, op2);
            }
        }
                x = a - b;
            return PyLong_FromLong(x);
#ifdef HAVE_LONG_LONG
        long_long:
                llx = lla - llb;
            return PyLong_FromLongLong(llx);
#endif
        
        
    }
    #endif
    if (PyFloat_CheckExact(op1)) {
        const long b = intval;
        double a = PyFloat_AS_DOUBLE(op1);
            double result;
            PyFPE_START_PROTECT("subtract", return NULL)
            result = ((double)a) - (double)b;
            PyFPE_END_PROTECT(result)
            return PyFloat_FromDouble(result);
    }
    return (inplace ? PyNumber_InPlaceSubtract : PyNumber_Subtract)(op1, op2);
}
#endif

/* PyUnicode_Substring */
static CYTHON_INLINE PyObject* __Pyx_PyUnicode_Substring(
            PyObject* text, Py_ssize_t start, Py_ssize_t stop) {
    Py_ssize_t length;
    if (unlikely(__Pyx_PyUnicode_READY(text) == -1)) return NULL;
    length = __Pyx_PyUnicode_GET_LENGTH(text);
    if (start < 0) {
        start += length;
        if (start < 0)
            start = 0;
    }
    if (stop < 0)
        stop += length;
    else if (stop > length)
        stop = length;
    length = stop - start;
    if (length <= 0)
        return PyUnicode_FromUnicode(NULL, 0);
#if CYTHON_PEP393_ENABLED
    return PyUnicode_FromKindAndData(PyUnicode_KIND(text),
        PyUnicode_1BYTE_DATA(text) + start*PyUnicode_KIND(text), stop-start);
#else
    return PyUnicode_FromUnicode(PyUnicode_AS_UNICODE(text)+start, stop-start);
#endif
}

/* PyObjectGetMethod */
static int __Pyx_PyObject_GetMethod(PyObject *obj, PyObject *name, PyObject **method) {
    PyObject *attr;
#if CYTHON_UNPACK_METHODS && CYTHON_COMPILING_IN_CPYTHON && CYTHON_USE_PYTYPE_LOOKUP
    PyTypeObject *tp = Py_TYPE(obj);
    PyObject *descr;
    descrgetfunc f = NULL;
    PyObject **dictptr, *dict;
    int meth_found = 0;
    assert (*method == NULL);
    if (unlikely(tp->tp_getattro != PyObject_GenericGetAttr)) {
        attr = __Pyx_PyObject_GetAttrStr(obj, name);
        goto try_unpack;
    }
    if (unlikely(tp->tp_dict == NULL) && unlikely(PyType_Ready(tp) < 0)) {
        return 0;
    }
    descr = _PyType_Lookup(tp, name);
    if (likely(descr != NULL)) {
        Py_INCREF(descr);
#if PY_MAJOR_VERSION >= 3
        #ifdef __Pyx_CyFunction_USED
        if (likely(PyFunction_Check(descr) || (Py_TYPE(descr) == &PyMethodDescr_Type) || __Pyx_CyFunction_Check(descr)))
        #else
        if (likely(PyFunction_Check(descr) || (Py_TYPE(descr) == &PyMethodDescr_Type)))
        #endif
#else
        #ifdef __Pyx_CyFunction_USED
        if (likely(PyFunction_Check(descr) || __Pyx_CyFunction_Check(descr)))
        #else
        if (likely(PyFunction_Check(descr)))
        #endif
#endif
        {
            meth_found = 1;
        } else {
            f = Py_TYPE(descr)->tp_descr_get;
            if (f != NULL && PyDescr_IsData(descr)) {
                attr = f(descr, obj, (PyObject *)Py_TYPE(obj));
                Py_DECREF(descr);
                goto try_unpack;
            }
        }
    }
    dictptr = _PyObject_GetDictPtr(obj);
    if (dictptr != NULL && (dict = *dictptr) != NULL) {
        Py_INCREF(dict);
        attr = __Pyx_PyDict_GetItemStr(dict, name);
        if (attr != NULL) {
            Py_INCREF(attr);
            Py_DECREF(dict);
            Py_XDECREF(descr);
            goto try_unpack;
        }
        Py_DECREF(dict);
    }
    if (meth_found) {
        *method = descr;
        return 1;
    }
    if (f != NULL) {
        attr = f(descr, obj, (PyObject *)Py_TYPE(obj));
        Py_DECREF(descr);
        goto try_unpack;
    }
    if (descr != NULL) {
        *method = descr;
        return 0;
    }
    PyErr_Format(PyExc_AttributeError,
#if PY_MAJOR_VERSION >= 3
                 "'%.50s' object has no attribute '%U'",
                 tp->tp_name, name);
#else
                 "'%.50s' object has no attribute '%.400s'",
                 tp->tp_name, PyString_AS_STRING(name));
#endif
    return 0;
#else
    attr = __Pyx_PyObject_GetAttrStr(obj, name);
    goto try_unpack;
#endif
try_unpack:
#if CYTHON_UNPACK_METHODS
    if (likely(attr) && PyMethod_Check(attr) && likely(PyMethod_GET_SELF(attr) == obj)) {
        PyObject *function = PyMethod_GET_FUNCTION(attr);
        Py_INCREF(function);
        Py_DECREF(attr);
        *method = function;
        return 1;
    }
#endif
    *method = attr;
    return 0;
}

/* PyObjectCallMethod0 */
static PyObject* __Pyx_PyObject_CallMethod0(PyObject* obj, PyObject* method_name) {
    PyObject *method = NULL, *result = NULL;
    int is_method = __Pyx_PyObject_GetMethod(obj, method_name, &method);
    if (likely(is_method)) {
        result = __Pyx_PyObject_CallOneArg(method, obj);
        Py_DECREF(method);
        return result;
    }
    if (unlikely(!method)) goto bad;
    result = __Pyx_PyObject_CallNoArg(method);
    Py_DECREF(method);
bad:
    return result;
}

/* RaiseNoneIterError */
static CYTHON_INLINE void __Pyx_RaiseNoneNotIterableError(void) {
    PyErr_SetString(PyExc_TypeError, "'NoneType' object is not iterable");
}

/* UnpackTupleError */
static void __Pyx_UnpackTupleError(PyObject *t, Py_ssize_t index) {
    if (t == Py_None) {
      __Pyx_RaiseNoneNotIterableError();
    } else if (PyTuple_GET_SIZE(t) < index) {
      __Pyx_RaiseNeedMoreValuesError(PyTuple_GET_SIZE(t));
    } else {
      __Pyx_RaiseTooManyValuesError(index);
    }
}

/* UnpackTuple2 */
static CYTHON_INLINE int __Pyx_unpack_tuple2_exact(
        PyObject* tuple, PyObject** pvalue1, PyObject** pvalue2, int decref_tuple) {
    PyObject *value1 = NULL, *value2 = NULL;
#if CYTHON_COMPILING_IN_PYPY
    value1 = PySequence_ITEM(tuple, 0);  if (unlikely(!value1)) goto bad;
    value2 = PySequence_ITEM(tuple, 1);  if (unlikely(!value2)) goto bad;
#else
    value1 = PyTuple_GET_ITEM(tuple, 0);  Py_INCREF(value1);
    value2 = PyTuple_GET_ITEM(tuple, 1);  Py_INCREF(value2);
#endif
    if (decref_tuple) {
        Py_DECREF(tuple);
    }
    *pvalue1 = value1;
    *pvalue2 = value2;
    return 0;
#if CYTHON_COMPILING_IN_PYPY
bad:
    Py_XDECREF(value1);
    Py_XDECREF(value2);
    if (decref_tuple) { Py_XDECREF(tuple); }
    return -1;
#endif
}
static int __Pyx_unpack_tuple2_generic(PyObject* tuple, PyObject** pvalue1, PyObject** pvalue2,
                                       int has_known_size, int decref_tuple) {
    Py_ssize_t index;
    PyObject *value1 = NULL, *value2 = NULL, *iter = NULL;
    iternextfunc iternext;
    iter = PyObject_GetIter(tuple);
    if (unlikely(!iter)) goto bad;
    if (decref_tuple) { Py_DECREF(tuple); tuple = NULL; }
    iternext = Py_TYPE(iter)->tp_iternext;
    value1 = iternext(iter); if (unlikely(!value1)) { index = 0; goto unpacking_failed; }
    value2 = iternext(iter); if (unlikely(!value2)) { index = 1; goto unpacking_failed; }
    if (!has_known_size && unlikely(__Pyx_IternextUnpackEndCheck(iternext(iter), 2))) goto bad;
    Py_DECREF(iter);
    *pvalue1 = value1;
    *pvalue2 = value2;
    return 0;
unpacking_failed:
    if (!has_known_size && __Pyx_IterFinish() == 0)
        __Pyx_RaiseNeedMoreValuesError(index);
bad:
    Py_XDECREF(iter);
    Py_XDECREF(value1);
    Py_XDECREF(value2);
    if (decref_tuple) { Py_XDECREF(tuple); }
    return -1;
}

/* dict_iter */
static CYTHON_INLINE PyObject* __Pyx_dict_iterator(PyObject* iterable, int is_dict, PyObject* method_name,
                                                   Py_ssize_t* p_orig_length, int* p_source_is_dict) {
    is_dict = is_dict || likely(PyDict_CheckExact(iterable));
    *p_source_is_dict = is_dict;
    if (is_dict) {
#if !CYTHON_COMPILING_IN_PYPY
        *p_orig_length = PyDict_Size(iterable);
        Py_INCREF(iterable);
        return iterable;
#elif PY_MAJOR_VERSION >= 3
        static PyObject *py_items = NULL, *py_keys = NULL, *py_values = NULL;
        PyObject **pp = NULL;
        if (method_name) {
            const char *name = PyUnicode_AsUTF8(method_name);
            if (strcmp(name, "iteritems") == 0) pp = &py_items;
            else if (strcmp(name, "iterkeys") == 0) pp = &py_keys;
            else if (strcmp(name, "itervalues") == 0) pp = &py_values;
            if (pp) {
                if (!*pp) {
                    *pp = PyUnicode_FromString(name + 4);
                    if (!*pp)
                        return NULL;
                }
                method_name = *pp;
            }
        }
#endif
    }
    *p_orig_length = 0;
    if (method_name) {
        PyObject* iter;
        iterable = __Pyx_PyObject_CallMethod0(iterable, method_name);
        if (!iterable)
            return NULL;
#if !CYTHON_COMPILING_IN_PYPY
        if (PyTuple_CheckExact(iterable) || PyList_CheckExact(iterable))
            return iterable;
#endif
        iter = PyObject_GetIter(iterable);
        Py_DECREF(iterable);
        return iter;
    }
    return PyObject_GetIter(iterable);
}
static CYTHON_INLINE int __Pyx_dict_iter_next(
        PyObject* iter_obj, CYTHON_NCP_UNUSED Py_ssize_t orig_length, CYTHON_NCP_UNUSED Py_ssize_t* ppos,
        PyObject** pkey, PyObject** pvalue, PyObject** pitem, int source_is_dict) {
    PyObject* next_item;
#if !CYTHON_COMPILING_IN_PYPY
    if (source_is_dict) {
        PyObject *key, *value;
        if (unlikely(orig_length != PyDict_Size(iter_obj))) {
            PyErr_SetString(PyExc_RuntimeError, "dictionary changed size during iteration");
            return -1;
        }
        if (unlikely(!PyDict_Next(iter_obj, ppos, &key, &value))) {
            return 0;
        }
        if (pitem) {
            PyObject* tuple = PyTuple_New(2);
            if (unlikely(!tuple)) {
                return -1;
            }
            Py_INCREF(key);
            Py_INCREF(value);
            PyTuple_SET_ITEM(tuple, 0, key);
            PyTuple_SET_ITEM(tuple, 1, value);
            *pitem = tuple;
        } else {
            if (pkey) {
                Py_INCREF(key);
                *pkey = key;
            }
            if (pvalue) {
                Py_INCREF(value);
                *pvalue = value;
            }
        }
        return 1;
    } else if (PyTuple_CheckExact(iter_obj)) {
        Py_ssize_t pos = *ppos;
        if (unlikely(pos >= PyTuple_GET_SIZE(iter_obj))) return 0;
        *ppos = pos + 1;
        next_item = PyTuple_GET_ITEM(iter_obj, pos);
        Py_INCREF(next_item);
    } else if (PyList_CheckExact(iter_obj)) {
        Py_ssize_t pos = *ppos;
        if (unlikely(pos >= PyList_GET_SIZE(iter_obj))) return 0;
        *ppos = pos + 1;
        next_item = PyList_GET_ITEM(iter_obj, pos);
        Py_INCREF(next_item);
    } else
#endif
    {
        next_item = PyIter_Next(iter_obj);
        if (unlikely(!next_item)) {
            return __Pyx_IterFinish();
        }
    }
    if (pitem) {
        *pitem = next_item;
    } else if (pkey && pvalue) {
        if (__Pyx_unpack_tuple2(next_item, pkey, pvalue, source_is_dict, source_is_dict, 1))
            return -1;
    } else if (pkey) {
        *pkey = next_item;
    } else {
        *pvalue = next_item;
    }
    return 1;
}

/* JoinPyUnicode */
static PyObject* __Pyx_PyUnicode_Join(PyObject* value_tuple, Py_ssize_t value_count, Py_ssize_t result_ulength,
                                      CYTHON_UNUSED Py_UCS4 max_char) {
#if CYTHON_USE_UNICODE_INTERNALS && CYTHON_ASSUME_SAFE_MACROS && !CYTHON_AVOID_BORROWED_REFS
    PyObject *result_uval;
    int result_ukind;
    Py_ssize_t i, char_pos;
    void *result_udata;
#if CYTHON_PEP393_ENABLED
    result_uval = PyUnicode_New(result_ulength, max_char);
    if (unlikely(!result_uval)) return NULL;
    result_ukind = (max_char <= 255) ? PyUnicode_1BYTE_KIND : (max_char <= 65535) ? PyUnicode_2BYTE_KIND : PyUnicode_4BYTE_KIND;
    result_udata = PyUnicode_DATA(result_uval);
#else
    result_uval = PyUnicode_FromUnicode(NULL, result_ulength);
    if (unlikely(!result_uval)) return NULL;
    result_ukind = sizeof(Py_UNICODE);
    result_udata = PyUnicode_AS_UNICODE(result_uval);
#endif
    char_pos = 0;
    for (i=0; i < value_count; i++) {
        int ukind;
        Py_ssize_t ulength;
        void *udata;
        PyObject *uval = PyTuple_GET_ITEM(value_tuple, i);
        if (unlikely(__Pyx_PyUnicode_READY(uval)))
            goto bad;
        ulength = __Pyx_PyUnicode_GET_LENGTH(uval);
        if (unlikely(!ulength))
            continue;
        if (unlikely(char_pos + ulength < 0))
            goto overflow;
        ukind = __Pyx_PyUnicode_KIND(uval);
        udata = __Pyx_PyUnicode_DATA(uval);
        if (!CYTHON_PEP393_ENABLED || ukind == result_ukind) {
            memcpy((char *)result_udata + char_pos * result_ukind, udata, (size_t) (ulength * result_ukind));
        } else {
            #if CYTHON_COMPILING_IN_CPYTHON && PY_VERSION_HEX >= 0x030300F0 || defined(_PyUnicode_FastCopyCharacters)
            _PyUnicode_FastCopyCharacters(result_uval, char_pos, uval, 0, ulength);
            #else
            Py_ssize_t j;
            for (j=0; j < ulength; j++) {
                Py_UCS4 uchar = __Pyx_PyUnicode_READ(ukind, udata, j);
                __Pyx_PyUnicode_WRITE(result_ukind, result_udata, char_pos+j, uchar);
            }
            #endif
        }
        char_pos += ulength;
    }
    return result_uval;
overflow:
    PyErr_SetString(PyExc_OverflowError, "join() result is too long for a Python string");
bad:
    Py_DECREF(result_uval);
    return NULL;
#else
    result_ulength++;
    value_count++;
    return PyUnicode_Join(__pyx_empty_unicode, value_tuple);
#endif
}

/* PyErrExceptionMatches */
#if CYTHON_FAST_THREAD_STATE
static int __Pyx_PyErr_ExceptionMatchesTuple(PyObject *exc_type, PyObject *tuple) {
    Py_ssize_t i, n;
    n = PyTuple_GET_SIZE(tuple);
#if PY_MAJOR_VERSION >= 3
    for (i=0; i<n; i++) {
        if (exc_type == PyTuple_GET_ITEM(tuple, i)) return 1;
    }
#endif
    for (i=0; i<n; i++) {
        if (__Pyx_PyErr_GivenExceptionMatches(exc_type, PyTuple_GET_ITEM(tuple, i))) return 1;
    }
    return 0;
}
static CYTHON_INLINE int __Pyx_PyErr_ExceptionMatchesInState(PyThreadState* tstate, PyObject* err) {
    PyObject *exc_type = tstate->curexc_type;
    if (exc_type == err) return 1;
    if (unlikely(!exc_type)) return 0;
    if (unlikely(PyTuple_Check(err)))
        return __Pyx_PyErr_ExceptionMatchesTuple(exc_type, err);
    return __Pyx_PyErr_GivenExceptionMatches(exc_type, err);
}
#endif

/* GetAttr */
static CYTHON_INLINE PyObject *__Pyx_GetAttr(PyObject *o, PyObject *n) {
#if CYTHON_USE_TYPE_SLOTS
#if PY_MAJOR_VERSION >= 3
    if (likely(PyUnicode_Check(n)))
#else
    if (likely(PyString_Check(n)))
#endif
        return __Pyx_PyObject_GetAttrStr(o, n);
#endif
    return PyObject_GetAttr(o, n);
}

/* GetAttr3 */
static PyObject *__Pyx_GetAttr3Default(PyObject *d) {
    __Pyx_PyThreadState_declare
    __Pyx_PyThreadState_assign
    if (unlikely(!__Pyx_PyErr_ExceptionMatches(PyExc_AttributeError)))
        return NULL;
    __Pyx_PyErr_Clear();
    Py_INCREF(d);
    return d;
}
static CYTHON_INLINE PyObject *__Pyx_GetAttr3(PyObject *o, PyObject *n, PyObject *d) {
    PyObject *r = __Pyx_GetAttr(o, n);
    return (likely(r)) ? r : __Pyx_GetAttr3Default(d);
}

/* ExtTypeTest */
static CYTHON_INLINE int __Pyx_TypeTest(PyObject *obj, PyTypeObject *type) {
    if (unlikely(!type)) {
        PyErr_SetString(PyExc_SystemError, "Missing type object");
        return 0;
    }
    if (likely(__Pyx_TypeCheck(obj, type)))
        return 1;
    PyErr_Format(PyExc_TypeError, "Cannot convert %.200s to %.200s",
                 Py_TYPE(obj)->tp_name, type->tp_name);
    return 0;
}

/* CallUnboundCMethod0 */
static PyObject* __Pyx__CallUnboundCMethod0(__Pyx_CachedCFunction* cfunc, PyObject* self) {
    PyObject *args, *result = NULL;
    if (unlikely(!cfunc->method) && unlikely(__Pyx_TryUnpackUnboundCMethod(cfunc) < 0)) return NULL;
#if CYTHON_ASSUME_SAFE_MACROS
    args = PyTuple_New(1);
    if (unlikely(!args)) goto bad;
    Py_INCREF(self);
    PyTuple_SET_ITEM(args, 0, self);
#else
    args = PyTuple_Pack(1, self);
    if (unlikely(!args)) goto bad;
#endif
    result = __Pyx_PyObject_Call(cfunc->method, args, NULL);
    Py_DECREF(args);
bad:
    return result;
}

/* py_dict_keys */
static CYTHON_INLINE PyObject* __Pyx_PyDict_Keys(PyObject* d) {
    if (PY_MAJOR_VERSION >= 3)
        return __Pyx_CallUnboundCMethod0(&__pyx_umethod_PyDict_Type_keys, d);
    else
        return PyDict_Keys(d);
}

/* SetItemInt */
static int __Pyx_SetItemInt_Generic(PyObject *o, PyObject *j, PyObject *v) {
    int r;
    if (!j) return -1;
    r = PyObject_SetItem(o, j, v);
    Py_DECREF(j);
    return r;
}
static CYTHON_INLINE int __Pyx_SetItemInt_Fast(PyObject *o, Py_ssize_t i, PyObject *v, int is_list,
                                               CYTHON_NCP_UNUSED int wraparound, CYTHON_NCP_UNUSED int boundscheck) {
#if CYTHON_ASSUME_SAFE_MACROS && !CYTHON_AVOID_BORROWED_REFS && CYTHON_USE_TYPE_SLOTS
    if (is_list || PyList_CheckExact(o)) {
        Py_ssize_t n = (!wraparound) ? i : ((likely(i >= 0)) ? i : i + PyList_GET_SIZE(o));
        if ((!boundscheck) || likely(__Pyx_is_valid_index(n, PyList_GET_SIZE(o)))) {
            PyObject* old = PyList_GET_ITEM(o, n);
            Py_INCREF(v);
            PyList_SET_ITEM(o, n, v);
            Py_DECREF(old);
            return 1;
        }
    } else {
        PySequenceMethods *m = Py_TYPE(o)->tp_as_sequence;
        if (likely(m && m->sq_ass_item)) {
            if (wraparound && unlikely(i < 0) && likely(m->sq_length)) {
                Py_ssize_t l = m->sq_length(o);
                if (likely(l >= 0)) {
                    i += l;
                } else {
                    if (!PyErr_ExceptionMatches(PyExc_OverflowError))
                        return -1;
                    PyErr_Clear();
                }
            }
            return m->sq_ass_item(o, i, v);
        }
    }
#else
#if CYTHON_COMPILING_IN_PYPY
    if (is_list || (PySequence_Check(o) && !PyDict_Check(o)))
#else
    if (is_list || PySequence_Check(o))
#endif
    {
        return PySequence_SetItem(o, i, v);
    }
#endif
    return __Pyx_SetItemInt_Generic(o, PyInt_FromSsize_t(i), v);
}

/* pop */
static CYTHON_INLINE PyObject* __Pyx__PyObject_Pop(PyObject* L) {
    if (Py_TYPE(L) == &PySet_Type) {
        return PySet_Pop(L);
    }
    return __Pyx_PyObject_CallMethod0(L, __pyx_n_s_pop);
}
#if CYTHON_USE_PYLIST_INTERNALS && CYTHON_ASSUME_SAFE_MACROS
static CYTHON_INLINE PyObject* __Pyx_PyList_Pop(PyObject* L) {
    if (likely(PyList_GET_SIZE(L) > (((PyListObject*)L)->allocated >> 1))) {
        Py_SIZE(L) -= 1;
        return PyList_GET_ITEM(L, PyList_GET_SIZE(L));
    }
    return __Pyx_CallUnboundCMethod0(&__pyx_umethod_PyList_Type_pop, L);
}
#endif

/* SliceObject */
static CYTHON_INLINE PyObject* __Pyx_PyObject_GetSlice(PyObject* obj,
        Py_ssize_t cstart, Py_ssize_t cstop,
        PyObject** _py_start, PyObject** _py_stop, PyObject** _py_slice,
        int has_cstart, int has_cstop, CYTHON_UNUSED int wraparound) {
#if CYTHON_USE_TYPE_SLOTS
    PyMappingMethods* mp;
#if PY_MAJOR_VERSION < 3
    PySequenceMethods* ms = Py_TYPE(obj)->tp_as_sequence;
    if (likely(ms && ms->sq_slice)) {
        if (!has_cstart) {
            if (_py_start && (*_py_start != Py_None)) {
                cstart = __Pyx_PyIndex_AsSsize_t(*_py_start);
                if ((cstart == (Py_ssize_t)-1) && PyErr_Occurred()) goto bad;
            } else
                cstart = 0;
        }
        if (!has_cstop) {
            if (_py_stop && (*_py_stop != Py_None)) {
                cstop = __Pyx_PyIndex_AsSsize_t(*_py_stop);
                if ((cstop == (Py_ssize_t)-1) && PyErr_Occurred()) goto bad;
            } else
                cstop = PY_SSIZE_T_MAX;
        }
        if (wraparound && unlikely((cstart < 0) | (cstop < 0)) && likely(ms->sq_length)) {
            Py_ssize_t l = ms->sq_length(obj);
            if (likely(l >= 0)) {
                if (cstop < 0) {
                    cstop += l;
                    if (cstop < 0) cstop = 0;
                }
                if (cstart < 0) {
                    cstart += l;
                    if (cstart < 0) cstart = 0;
                }
            } else {
                if (!PyErr_ExceptionMatches(PyExc_OverflowError))
                    goto bad;
                PyErr_Clear();
            }
        }
        return ms->sq_slice(obj, cstart, cstop);
    }
#endif
    mp = Py_TYPE(obj)->tp_as_mapping;
    if (likely(mp && mp->mp_subscript))
#endif
    {
        PyObject* result;
        PyObject *py_slice, *py_start, *py_stop;
        if (_py_slice) {
            py_slice = *_py_slice;
        } else {
            PyObject* owned_start = NULL;
            PyObject* owned_stop = NULL;
            if (_py_start) {
                py_start = *_py_start;
            } else {
                if (has_cstart) {
                    owned_start = py_start = PyInt_FromSsize_t(cstart);
                    if (unlikely(!py_start)) goto bad;
                } else
                    py_start = Py_None;
            }
            if (_py_stop) {
                py_stop = *_py_stop;
            } else {
                if (has_cstop) {
                    owned_stop = py_stop = PyInt_FromSsize_t(cstop);
                    if (unlikely(!py_stop)) {
                        Py_XDECREF(owned_start);
                        goto bad;
                    }
                } else
                    py_stop = Py_None;
            }
            py_slice = PySlice_New(py_start, py_stop, Py_None);
            Py_XDECREF(owned_start);
            Py_XDECREF(owned_stop);
            if (unlikely(!py_slice)) goto bad;
        }
#if CYTHON_USE_TYPE_SLOTS
        result = mp->mp_subscript(obj, py_slice);
#else
        result = PyObject_GetItem(obj, py_slice);
#endif
        if (!_py_slice) {
            Py_DECREF(py_slice);
        }
        return result;
    }
    PyErr_Format(PyExc_TypeError,
        "'%.200s' object is unsliceable", Py_TYPE(obj)->tp_name);
bad:
    return NULL;
}

/* pyfrozenset_new */
static CYTHON_INLINE PyObject* __Pyx_PyFrozenSet_New(PyObject* it) {
    if (it) {
        PyObject* result;
#if CYTHON_COMPILING_IN_PYPY
        PyObject* args;
        args = PyTuple_Pack(1, it);
        if (unlikely(!args))
            return NULL;
        result = PyObject_Call((PyObject*)&PyFrozenSet_Type, args, NULL);
        Py_DECREF(args);
        return result;
#else
        if (PyFrozenSet_CheckExact(it)) {
            Py_INCREF(it);
            return it;
        }
        result = PyFrozenSet_New(it);
        if (unlikely(!result))
            return NULL;
        if (likely(PySet_GET_SIZE(result)))
            return result;
        Py_DECREF(result);
#endif
    }
#if CYTHON_USE_TYPE_SLOTS
    return PyFrozenSet_Type.tp_new(&PyFrozenSet_Type, __pyx_empty_tuple, NULL);
#else
    return PyObject_Call((PyObject*)&PyFrozenSet_Type, __pyx_empty_tuple, NULL);
#endif
}

/* PySetContains */
static int __Pyx_PySet_ContainsUnhashable(PyObject *set, PyObject *key) {
    int result = -1;
    if (PySet_Check(key) && PyErr_ExceptionMatches(PyExc_TypeError)) {
        PyObject *tmpkey;
        PyErr_Clear();
        tmpkey = __Pyx_PyFrozenSet_New(key);
        if (tmpkey != NULL) {
            result = PySet_Contains(set, tmpkey);
            Py_DECREF(tmpkey);
        }
    }
    return result;
}
static CYTHON_INLINE int __Pyx_PySet_ContainsTF(PyObject* key, PyObject* set, int eq) {
    int result = PySet_Contains(set, key);
    if (unlikely(result < 0)) {
        result = __Pyx_PySet_ContainsUnhashable(set, key);
    }
    return unlikely(result < 0) ? result : (result == (eq == Py_EQ));
}

/* None */
static CYTHON_INLINE void __Pyx_RaiseUnboundLocalError(const char *varname) {
    PyErr_Format(PyExc_UnboundLocalError, "local variable '%s' referenced before assignment", varname);
}

/* PyObjectCallMethod1 */
static PyObject* __Pyx__PyObject_CallMethod1(PyObject* method, PyObject* arg) {
    PyObject *result = __Pyx_PyObject_CallOneArg(method, arg);
    Py_DECREF(method);
    return result;
}
static PyObject* __Pyx_PyObject_CallMethod1(PyObject* obj, PyObject* method_name, PyObject* arg) {
    PyObject *method = NULL, *result;
    int is_method = __Pyx_PyObject_GetMethod(obj, method_name, &method);
    if (likely(is_method)) {
        result = __Pyx_PyObject_Call2Args(method, obj, arg);
        Py_DECREF(method);
        return result;
    }
    if (unlikely(!method)) return NULL;
    return __Pyx__PyObject_CallMethod1(method, arg);
}

/* append */
static CYTHON_INLINE int __Pyx_PyObject_Append(PyObject* L, PyObject* x) {
    if (likely(PyList_CheckExact(L))) {
        if (unlikely(__Pyx_PyList_Append(L, x) < 0)) return -1;
    } else {
        PyObject* retval = __Pyx_PyObject_CallMethod1(L, __pyx_n_s_append, x);
        if (unlikely(!retval))
            return -1;
        Py_DECREF(retval);
    }
    return 0;
}

/* RaiseException */
#if PY_MAJOR_VERSION < 3
static void __Pyx_Raise(PyObject *type, PyObject *value, PyObject *tb,
                        CYTHON_UNUSED PyObject *cause) {
    __Pyx_PyThreadState_declare
    Py_XINCREF(type);
    if (!value || value == Py_None)
        value = NULL;
    else
        Py_INCREF(value);
    if (!tb || tb == Py_None)
        tb = NULL;
    else {
        Py_INCREF(tb);
        if (!PyTraceBack_Check(tb)) {
            PyErr_SetString(PyExc_TypeError,
                "raise: arg 3 must be a traceback or None");
            goto raise_error;
        }
    }
    if (PyType_Check(type)) {
#if CYTHON_COMPILING_IN_PYPY
        if (!value) {
            Py_INCREF(Py_None);
            value = Py_None;
        }
#endif
        PyErr_NormalizeException(&type, &value, &tb);
    } else {
        if (value) {
            PyErr_SetString(PyExc_TypeError,
                "instance exception may not have a separate value");
            goto raise_error;
        }
        value = type;
        type = (PyObject*) Py_TYPE(type);
        Py_INCREF(type);
        if (!PyType_IsSubtype((PyTypeObject *)type, (PyTypeObject *)PyExc_BaseException)) {
            PyErr_SetString(PyExc_TypeError,
                "raise: exception class must be a subclass of BaseException");
            goto raise_error;
        }
    }
    __Pyx_PyThreadState_assign
    __Pyx_ErrRestore(type, value, tb);
    return;
raise_error:
    Py_XDECREF(value);
    Py_XDECREF(type);
    Py_XDECREF(tb);
    return;
}
#else
static void __Pyx_Raise(PyObject *type, PyObject *value, PyObject *tb, PyObject *cause) {
    PyObject* owned_instance = NULL;
    if (tb == Py_None) {
        tb = 0;
    } else if (tb && !PyTraceBack_Check(tb)) {
        PyErr_SetString(PyExc_TypeError,
            "raise: arg 3 must be a traceback or None");
        goto bad;
    }
    if (value == Py_None)
        value = 0;
    if (PyExceptionInstance_Check(type)) {
        if (value) {
            PyErr_SetString(PyExc_TypeError,
                "instance exception may not have a separate value");
            goto bad;
        }
        value = type;
        type = (PyObject*) Py_TYPE(value);
    } else if (PyExceptionClass_Check(type)) {
        PyObject *instance_class = NULL;
        if (value && PyExceptionInstance_Check(value)) {
            instance_class = (PyObject*) Py_TYPE(value);
            if (instance_class != type) {
                int is_subclass = PyObject_IsSubclass(instance_class, type);
                if (!is_subclass) {
                    instance_class = NULL;
                } else if (unlikely(is_subclass == -1)) {
                    goto bad;
                } else {
                    type = instance_class;
                }
            }
        }
        if (!instance_class) {
            PyObject *args;
            if (!value)
                args = PyTuple_New(0);
            else if (PyTuple_Check(value)) {
                Py_INCREF(value);
                args = value;
            } else
                args = PyTuple_Pack(1, value);
            if (!args)
                goto bad;
            owned_instance = PyObject_Call(type, args, NULL);
            Py_DECREF(args);
            if (!owned_instance)
                goto bad;
            value = owned_instance;
            if (!PyExceptionInstance_Check(value)) {
                PyErr_Format(PyExc_TypeError,
                             "calling %R should have returned an instance of "
                             "BaseException, not %R",
                             type, Py_TYPE(value));
                goto bad;
            }
        }
    } else {
        PyErr_SetString(PyExc_TypeError,
            "raise: exception class must be a subclass of BaseException");
        goto bad;
    }
    if (cause) {
        PyObject *fixed_cause;
        if (cause == Py_None) {
            fixed_cause = NULL;
        } else if (PyExceptionClass_Check(cause)) {
            fixed_cause = PyObject_CallObject(cause, NULL);
            if (fixed_cause == NULL)
                goto bad;
        } else if (PyExceptionInstance_Check(cause)) {
            fixed_cause = cause;
            Py_INCREF(fixed_cause);
        } else {
            PyErr_SetString(PyExc_TypeError,
                            "exception causes must derive from "
                            "BaseException");
            goto bad;
        }
        PyException_SetCause(value, fixed_cause);
    }
    PyErr_SetObject(type, value);
    if (tb) {
#if CYTHON_COMPILING_IN_PYPY
        PyObject *tmp_type, *tmp_value, *tmp_tb;
        PyErr_Fetch(&tmp_type, &tmp_value, &tmp_tb);
        Py_INCREF(tb);
        PyErr_Restore(tmp_type, tmp_value, tb);
        Py_XDECREF(tmp_tb);
#else
        PyThreadState *tstate = __Pyx_PyThreadState_Current;
        PyObject* tmp_tb = tstate->curexc_traceback;
        if (tb != tmp_tb) {
            Py_INCREF(tb);
            tstate->curexc_traceback = tb;
            Py_XDECREF(tmp_tb);
        }
#endif
    }
bad:
    Py_XDECREF(owned_instance);
    return;
}
#endif

/* SliceTupleAndList */
#if CYTHON_COMPILING_IN_CPYTHON
static CYTHON_INLINE void __Pyx_crop_slice(Py_ssize_t* _start, Py_ssize_t* _stop, Py_ssize_t* _length) {
    Py_ssize_t start = *_start, stop = *_stop, length = *_length;
    if (start < 0) {
        start += length;
        if (start < 0)
            start = 0;
    }
    if (stop < 0)
        stop += length;
    else if (stop > length)
        stop = length;
    *_length = stop - start;
    *_start = start;
    *_stop = stop;
}
static CYTHON_INLINE void __Pyx_copy_object_array(PyObject** CYTHON_RESTRICT src, PyObject** CYTHON_RESTRICT dest, Py_ssize_t length) {
    PyObject *v;
    Py_ssize_t i;
    for (i = 0; i < length; i++) {
        v = dest[i] = src[i];
        Py_INCREF(v);
    }
}
static CYTHON_INLINE PyObject* __Pyx_PyList_GetSlice(
            PyObject* src, Py_ssize_t start, Py_ssize_t stop) {
    PyObject* dest;
    Py_ssize_t length = PyList_GET_SIZE(src);
    __Pyx_crop_slice(&start, &stop, &length);
    if (unlikely(length <= 0))
        return PyList_New(0);
    dest = PyList_New(length);
    if (unlikely(!dest))
        return NULL;
    __Pyx_copy_object_array(
        ((PyListObject*)src)->ob_item + start,
        ((PyListObject*)dest)->ob_item,
        length);
    return dest;
}
static CYTHON_INLINE PyObject* __Pyx_PyTuple_GetSlice(
            PyObject* src, Py_ssize_t start, Py_ssize_t stop) {
    PyObject* dest;
    Py_ssize_t length = PyTuple_GET_SIZE(src);
    __Pyx_crop_slice(&start, &stop, &length);
    if (unlikely(length <= 0))
        return PyTuple_New(0);
    dest = PyTuple_New(length);
    if (unlikely(!dest))
        return NULL;
    __Pyx_copy_object_array(
        ((PyTupleObject*)src)->ob_item + start,
        ((PyTupleObject*)dest)->ob_item,
        length);
    return dest;
}
#endif

/* unicode_iter */
static CYTHON_INLINE int __Pyx_init_unicode_iteration(
    PyObject* ustring, Py_ssize_t *length, void** data, int *kind) {
#if CYTHON_PEP393_ENABLED
    if (unlikely(__Pyx_PyUnicode_READY(ustring) < 0)) return -1;
    *kind   = PyUnicode_KIND(ustring);
    *length = PyUnicode_GET_LENGTH(ustring);
    *data   = PyUnicode_DATA(ustring);
#else
    *kind   = 0;
    *length = PyUnicode_GET_SIZE(ustring);
    *data   = (void*)PyUnicode_AS_UNICODE(ustring);
#endif
    return 0;
}

/* GetItemIntUnicode */
static CYTHON_INLINE Py_UCS4 __Pyx_GetItemInt_Unicode_Fast(PyObject* ustring, Py_ssize_t i,
                                                           int wraparound, int boundscheck) {
    Py_ssize_t length;
    if (unlikely(__Pyx_PyUnicode_READY(ustring) < 0)) return (Py_UCS4)-1;
    if (wraparound | boundscheck) {
        length = __Pyx_PyUnicode_GET_LENGTH(ustring);
        if (wraparound & unlikely(i < 0)) i += length;
        if ((!boundscheck) || likely(__Pyx_is_valid_index(i, length))) {
            return __Pyx_PyUnicode_READ_CHAR(ustring, i);
        } else {
            PyErr_SetString(PyExc_IndexError, "string index out of range");
            return (Py_UCS4)-1;
        }
    } else {
        return __Pyx_PyUnicode_READ_CHAR(ustring, i);
    }
}

/* GetTopmostException */
#if CYTHON_USE_EXC_INFO_STACK
static _PyErr_StackItem *
__Pyx_PyErr_GetTopmostException(PyThreadState *tstate)
{
    _PyErr_StackItem *exc_info = tstate->exc_info;
    while ((exc_info->exc_type == NULL || exc_info->exc_type == Py_None) &&
           exc_info->previous_item != NULL)
    {
        exc_info = exc_info->previous_item;
    }
    return exc_info;
}
#endif

/* SaveResetException */
#if CYTHON_FAST_THREAD_STATE
static CYTHON_INLINE void __Pyx__ExceptionSave(PyThreadState *tstate, PyObject **type, PyObject **value, PyObject **tb) {
    #if CYTHON_USE_EXC_INFO_STACK
    _PyErr_StackItem *exc_info = __Pyx_PyErr_GetTopmostException(tstate);
    *type = exc_info->exc_type;
    *value = exc_info->exc_value;
    *tb = exc_info->exc_traceback;
    #else
    *type = tstate->exc_type;
    *value = tstate->exc_value;
    *tb = tstate->exc_traceback;
    #endif
    Py_XINCREF(*type);
    Py_XINCREF(*value);
    Py_XINCREF(*tb);
}
static CYTHON_INLINE void __Pyx__ExceptionReset(PyThreadState *tstate, PyObject *type, PyObject *value, PyObject *tb) {
    PyObject *tmp_type, *tmp_value, *tmp_tb;
    #if CYTHON_USE_EXC_INFO_STACK
    _PyErr_StackItem *exc_info = tstate->exc_info;
    tmp_type = exc_info->exc_type;
    tmp_value = exc_info->exc_value;
    tmp_tb = exc_info->exc_traceback;
    exc_info->exc_type = type;
    exc_info->exc_value = value;
    exc_info->exc_traceback = tb;
    #else
    tmp_type = tstate->exc_type;
    tmp_value = tstate->exc_value;
    tmp_tb = tstate->exc_traceback;
    tstate->exc_type = type;
    tstate->exc_value = value;
    tstate->exc_traceback = tb;
    #endif
    Py_XDECREF(tmp_type);
    Py_XDECREF(tmp_value);
    Py_XDECREF(tmp_tb);
}
#endif

/* GetException */
#if CYTHON_FAST_THREAD_STATE
static int __Pyx__GetException(PyThreadState *tstate, PyObject **type, PyObject **value, PyObject **tb)
#else
static int __Pyx_GetException(PyObject **type, PyObject **value, PyObject **tb)
#endif
{
    PyObject *local_type, *local_value, *local_tb;
#if CYTHON_FAST_THREAD_STATE
    PyObject *tmp_type, *tmp_value, *tmp_tb;
    local_type = tstate->curexc_type;
    local_value = tstate->curexc_value;
    local_tb = tstate->curexc_traceback;
    tstate->curexc_type = 0;
    tstate->curexc_value = 0;
    tstate->curexc_traceback = 0;
#else
    PyErr_Fetch(&local_type, &local_value, &local_tb);
#endif
    PyErr_NormalizeException(&local_type, &local_value, &local_tb);
#if CYTHON_FAST_THREAD_STATE
    if (unlikely(tstate->curexc_type))
#else
    if (unlikely(PyErr_Occurred()))
#endif
        goto bad;
    #if PY_MAJOR_VERSION >= 3
    if (local_tb) {
        if (unlikely(PyException_SetTraceback(local_value, local_tb) < 0))
            goto bad;
    }
    #endif
    Py_XINCREF(local_tb);
    Py_XINCREF(local_type);
    Py_XINCREF(local_value);
    *type = local_type;
    *value = local_value;
    *tb = local_tb;
#if CYTHON_FAST_THREAD_STATE
    #if CYTHON_USE_EXC_INFO_STACK
    {
        _PyErr_StackItem *exc_info = tstate->exc_info;
        tmp_type = exc_info->exc_type;
        tmp_value = exc_info->exc_value;
        tmp_tb = exc_info->exc_traceback;
        exc_info->exc_type = local_type;
        exc_info->exc_value = local_value;
        exc_info->exc_traceback = local_tb;
    }
    #else
    tmp_type = tstate->exc_type;
    tmp_value = tstate->exc_value;
    tmp_tb = tstate->exc_traceback;
    tstate->exc_type = local_type;
    tstate->exc_value = local_value;
    tstate->exc_traceback = local_tb;
    #endif
    Py_XDECREF(tmp_type);
    Py_XDECREF(tmp_value);
    Py_XDECREF(tmp_tb);
#else
    PyErr_SetExcInfo(local_type, local_value, local_tb);
#endif
    return 0;
bad:
    *type = 0;
    *value = 0;
    *tb = 0;
    Py_XDECREF(local_type);
    Py_XDECREF(local_value);
    Py_XDECREF(local_tb);
    return -1;
}

/* BufferIndexError */
static void __Pyx_RaiseBufferIndexError(int axis) {
  PyErr_Format(PyExc_IndexError,
     "Out of bounds on buffer access (axis %d)", axis);
}

/* SliceObject */
static CYTHON_INLINE int __Pyx_PyObject_SetSlice(PyObject* obj, PyObject* value,
        Py_ssize_t cstart, Py_ssize_t cstop,
        PyObject** _py_start, PyObject** _py_stop, PyObject** _py_slice,
        int has_cstart, int has_cstop, CYTHON_UNUSED int wraparound) {
#if CYTHON_USE_TYPE_SLOTS
    PyMappingMethods* mp;
#if PY_MAJOR_VERSION < 3
    PySequenceMethods* ms = Py_TYPE(obj)->tp_as_sequence;
    if (likely(ms && ms->sq_ass_slice)) {
        if (!has_cstart) {
            if (_py_start && (*_py_start != Py_None)) {
                cstart = __Pyx_PyIndex_AsSsize_t(*_py_start);
                if ((cstart == (Py_ssize_t)-1) && PyErr_Occurred()) goto bad;
            } else
                cstart = 0;
        }
        if (!has_cstop) {
            if (_py_stop && (*_py_stop != Py_None)) {
                cstop = __Pyx_PyIndex_AsSsize_t(*_py_stop);
                if ((cstop == (Py_ssize_t)-1) && PyErr_Occurred()) goto bad;
            } else
                cstop = PY_SSIZE_T_MAX;
        }
        if (wraparound && unlikely((cstart < 0) | (cstop < 0)) && likely(ms->sq_length)) {
            Py_ssize_t l = ms->sq_length(obj);
            if (likely(l >= 0)) {
                if (cstop < 0) {
                    cstop += l;
                    if (cstop < 0) cstop = 0;
                }
                if (cstart < 0) {
                    cstart += l;
                    if (cstart < 0) cstart = 0;
                }
            } else {
                if (!PyErr_ExceptionMatches(PyExc_OverflowError))
                    goto bad;
                PyErr_Clear();
            }
        }
        return ms->sq_ass_slice(obj, cstart, cstop, value);
    }
#endif
    mp = Py_TYPE(obj)->tp_as_mapping;
    if (likely(mp && mp->mp_ass_subscript))
#endif
    {
        int result;
        PyObject *py_slice, *py_start, *py_stop;
        if (_py_slice) {
            py_slice = *_py_slice;
        } else {
            PyObject* owned_start = NULL;
            PyObject* owned_stop = NULL;
            if (_py_start) {
                py_start = *_py_start;
            } else {
                if (has_cstart) {
                    owned_start = py_start = PyInt_FromSsize_t(cstart);
                    if (unlikely(!py_start)) goto bad;
                } else
                    py_start = Py_None;
            }
            if (_py_stop) {
                py_stop = *_py_stop;
            } else {
                if (has_cstop) {
                    owned_stop = py_stop = PyInt_FromSsize_t(cstop);
                    if (unlikely(!py_stop)) {
                        Py_XDECREF(owned_start);
                        goto bad;
                    }
                } else
                    py_stop = Py_None;
            }
            py_slice = PySlice_New(py_start, py_stop, Py_None);
            Py_XDECREF(owned_start);
            Py_XDECREF(owned_stop);
            if (unlikely(!py_slice)) goto bad;
        }
#if CYTHON_USE_TYPE_SLOTS
        result = mp->mp_ass_subscript(obj, py_slice, value);
#else
        result = value ? PyObject_SetItem(obj, py_slice, value) : PyObject_DelItem(obj, py_slice);
#endif
        if (!_py_slice) {
            Py_DECREF(py_slice);
        }
        return result;
    }
    PyErr_Format(PyExc_TypeError,
        "'%.200s' object does not support slice %.10s",
        Py_TYPE(obj)->tp_name, value ? "assignment" : "deletion");
bad:
    return -1;
}

/* MemviewSliceInit */
static int
__Pyx_init_memviewslice(struct __pyx_memoryview_obj *memview,
                        int ndim,
                        __Pyx_memviewslice *memviewslice,
                        int memview_is_new_reference)
{
    __Pyx_RefNannyDeclarations
    int i, retval=-1;
    Py_buffer *buf = &memview->view;
    __Pyx_RefNannySetupContext("init_memviewslice", 0);
    if (memviewslice->memview || memviewslice->data) {
        PyErr_SetString(PyExc_ValueError,
            "memviewslice is already initialized!");
        goto fail;
    }
    if (buf->strides) {
        for (i = 0; i < ndim; i++) {
            memviewslice->strides[i] = buf->strides[i];
        }
    } else {
        Py_ssize_t stride = buf->itemsize;
        for (i = ndim - 1; i >= 0; i--) {
            memviewslice->strides[i] = stride;
            stride *= buf->shape[i];
        }
    }
    for (i = 0; i < ndim; i++) {
        memviewslice->shape[i]   = buf->shape[i];
        if (buf->suboffsets) {
            memviewslice->suboffsets[i] = buf->suboffsets[i];
        } else {
            memviewslice->suboffsets[i] = -1;
        }
    }
    memviewslice->memview = memview;
    memviewslice->data = (char *)buf->buf;
    if (__pyx_add_acquisition_count(memview) == 0 && !memview_is_new_reference) {
        Py_INCREF(memview);
    }
    retval = 0;
    goto no_fail;
fail:
    memviewslice->memview = 0;
    memviewslice->data = 0;
    retval = -1;
no_fail:
    __Pyx_RefNannyFinishContext();
    return retval;
}
#ifndef Py_NO_RETURN
#define Py_NO_RETURN
#endif
static void __pyx_fatalerror(const char *fmt, ...) Py_NO_RETURN {
    va_list vargs;
    char msg[200];
#ifdef HAVE_STDARG_PROTOTYPES
    va_start(vargs, fmt);
#else
    va_start(vargs);
#endif
    vsnprintf(msg, 200, fmt, vargs);
    va_end(vargs);
    Py_FatalError(msg);
}
static CYTHON_INLINE int
__pyx_add_acquisition_count_locked(__pyx_atomic_int *acquisition_count,
                                   PyThread_type_lock lock)
{
    int result;
    PyThread_acquire_lock(lock, 1);
    result = (*acquisition_count)++;
    PyThread_release_lock(lock);
    return result;
}
static CYTHON_INLINE int
__pyx_sub_acquisition_count_locked(__pyx_atomic_int *acquisition_count,
                                   PyThread_type_lock lock)
{
    int result;
    PyThread_acquire_lock(lock, 1);
    result = (*acquisition_count)--;
    PyThread_release_lock(lock);
    return result;
}
static CYTHON_INLINE void
__Pyx_INC_MEMVIEW(__Pyx_memviewslice *memslice, int have_gil, int lineno)
{
    int first_time;
    struct __pyx_memoryview_obj *memview = memslice->memview;
    if (!memview || (PyObject *) memview == Py_None)
        return;
    if (__pyx_get_slice_count(memview) < 0)
        __pyx_fatalerror("Acquisition count is %d (line %d)",
                         __pyx_get_slice_count(memview), lineno);
    first_time = __pyx_add_acquisition_count(memview) == 0;
    if (first_time) {
        if (have_gil) {
            Py_INCREF((PyObject *) memview);
        } else {
            PyGILState_STATE _gilstate = PyGILState_Ensure();
            Py_INCREF((PyObject *) memview);
            PyGILState_Release(_gilstate);
        }
    }
}
static CYTHON_INLINE void __Pyx_XDEC_MEMVIEW(__Pyx_memviewslice *memslice,
                                             int have_gil, int lineno) {
    int last_time;
    struct __pyx_memoryview_obj *memview = memslice->memview;
    if (!memview ) {
        return;
    } else if ((PyObject *) memview == Py_None) {
        memslice->memview = NULL;
        return;
    }
    if (__pyx_get_slice_count(memview) <= 0)
        __pyx_fatalerror("Acquisition count is %d (line %d)",
                         __pyx_get_slice_count(memview), lineno);
    last_time = __pyx_sub_acquisition_count(memview) == 1;
    memslice->data = NULL;
    if (last_time) {
        if (have_gil) {
            Py_CLEAR(memslice->memview);
        } else {
            PyGILState_STATE _gilstate = PyGILState_Ensure();
            Py_CLEAR(memslice->memview);
            PyGILState_Release(_gilstate);
        }
    } else {
        memslice->memview = NULL;
    }
}

/* IterNext */
static PyObject *__Pyx_PyIter_Next2Default(PyObject* defval) {
    PyObject* exc_type;
    __Pyx_PyThreadState_declare
    __Pyx_PyThreadState_assign
    exc_type = __Pyx_PyErr_Occurred();
    if (unlikely(exc_type)) {
        if (!defval || unlikely(!__Pyx_PyErr_GivenExceptionMatches(exc_type, PyExc_StopIteration)))
            return NULL;
        __Pyx_PyErr_Clear();
        Py_INCREF(defval);
        return defval;
    }
    if (defval) {
        Py_INCREF(defval);
        return defval;
    }
    __Pyx_PyErr_SetNone(PyExc_StopIteration);
    return NULL;
}
static void __Pyx_PyIter_Next_ErrorNoIterator(PyObject *iterator) {
    PyErr_Format(PyExc_TypeError,
        "%.200s object is not an iterator", Py_TYPE(iterator)->tp_name);
}
static CYTHON_INLINE PyObject *__Pyx_PyIter_Next2(PyObject* iterator, PyObject* defval) {
    PyObject* next;
    iternextfunc iternext = Py_TYPE(iterator)->tp_iternext;
    if (likely(iternext)) {
#if CYTHON_USE_TYPE_SLOTS
        next = iternext(iterator);
        if (likely(next))
            return next;
        #if PY_VERSION_HEX >= 0x02070000
        if (unlikely(iternext == &_PyObject_NextNotImplemented))
            return NULL;
        #endif
#else
        next = PyIter_Next(iterator);
        if (likely(next))
            return next;
#endif
    } else if (CYTHON_USE_TYPE_SLOTS || unlikely(!PyIter_Check(iterator))) {
        __Pyx_PyIter_Next_ErrorNoIterator(iterator);
        return NULL;
    }
#if !CYTHON_USE_TYPE_SLOTS
    else {
        next = PyIter_Next(iterator);
        if (likely(next))
            return next;
    }
#endif
    return __Pyx_PyIter_Next2Default(defval);
}

/* DelItemInt */
static int __Pyx_DelItem_Generic(PyObject *o, PyObject *j) {
    int r;
    if (!j) return -1;
    r = PyObject_DelItem(o, j);
    Py_DECREF(j);
    return r;
}
static CYTHON_INLINE int __Pyx_DelItemInt_Fast(PyObject *o, Py_ssize_t i,
                                               CYTHON_UNUSED int is_list, CYTHON_NCP_UNUSED int wraparound) {
#if !CYTHON_USE_TYPE_SLOTS
    if (is_list || PySequence_Check(o)) {
        return PySequence_DelItem(o, i);
    }
#else
    PySequenceMethods *m = Py_TYPE(o)->tp_as_sequence;
    if (likely(m && m->sq_ass_item)) {
        if (wraparound && unlikely(i < 0) && likely(m->sq_length)) {
            Py_ssize_t l = m->sq_length(o);
            if (likely(l >= 0)) {
                i += l;
            } else {
                if (!PyErr_ExceptionMatches(PyExc_OverflowError))
                    return -1;
                PyErr_Clear();
            }
        }
        return m->sq_ass_item(o, i, (PyObject *)NULL);
    }
#endif
    return __Pyx_DelItem_Generic(o, PyInt_FromSsize_t(i));
}

/* PyIntCompare */
static CYTHON_INLINE PyObject* __Pyx_PyInt_EqObjC(PyObject *op1, PyObject *op2, CYTHON_UNUSED long intval, CYTHON_UNUSED long inplace) {
    if (op1 == op2) {
        Py_RETURN_TRUE;
    }
    #if PY_MAJOR_VERSION < 3
    if (likely(PyInt_CheckExact(op1))) {
        const long b = intval;
        long a = PyInt_AS_LONG(op1);
        if (a == b) Py_RETURN_TRUE; else Py_RETURN_FALSE;
    }
    #endif
    #if CYTHON_USE_PYLONG_INTERNALS
    if (likely(PyLong_CheckExact(op1))) {
        int unequal;
        unsigned long uintval;
        Py_ssize_t size = Py_SIZE(op1);
        const digit* digits = ((PyLongObject*)op1)->ob_digit;
        if (intval == 0) {
            if (size == 0) Py_RETURN_TRUE; else Py_RETURN_FALSE;
        } else if (intval < 0) {
            if (size >= 0)
                Py_RETURN_FALSE;
            intval = -intval;
            size = -size;
        } else {
            if (size <= 0)
                Py_RETURN_FALSE;
        }
        uintval = (unsigned long) intval;
#if PyLong_SHIFT * 4 < SIZEOF_LONG*8
        if (uintval >> (PyLong_SHIFT * 4)) {
            unequal = (size != 5) || (digits[0] != (uintval & (unsigned long) PyLong_MASK))
                 | (digits[1] != ((uintval >> (1 * PyLong_SHIFT)) & (unsigned long) PyLong_MASK)) | (digits[2] != ((uintval >> (2 * PyLong_SHIFT)) & (unsigned long) PyLong_MASK)) | (digits[3] != ((uintval >> (3 * PyLong_SHIFT)) & (unsigned long) PyLong_MASK)) | (digits[4] != ((uintval >> (4 * PyLong_SHIFT)) & (unsigned long) PyLong_MASK));
        } else
#endif
#if PyLong_SHIFT * 3 < SIZEOF_LONG*8
        if (uintval >> (PyLong_SHIFT * 3)) {
            unequal = (size != 4) || (digits[0] != (uintval & (unsigned long) PyLong_MASK))
                 | (digits[1] != ((uintval >> (1 * PyLong_SHIFT)) & (unsigned long) PyLong_MASK)) | (digits[2] != ((uintval >> (2 * PyLong_SHIFT)) & (unsigned long) PyLong_MASK)) | (digits[3] != ((uintval >> (3 * PyLong_SHIFT)) & (unsigned long) PyLong_MASK));
        } else
#endif
#if PyLong_SHIFT * 2 < SIZEOF_LONG*8
        if (uintval >> (PyLong_SHIFT * 2)) {
            unequal = (size != 3) || (digits[0] != (uintval & (unsigned long) PyLong_MASK))
                 | (digits[1] != ((uintval >> (1 * PyLong_SHIFT)) & (unsigned long) PyLong_MASK)) | (digits[2] != ((uintval >> (2 * PyLong_SHIFT)) & (unsigned long) PyLong_MASK));
        } else
#endif
#if PyLong_SHIFT * 1 < SIZEOF_LONG*8
        if (uintval >> (PyLong_SHIFT * 1)) {
            unequal = (size != 2) || (digits[0] != (uintval & (unsigned long) PyLong_MASK))
                 | (digits[1] != ((uintval >> (1 * PyLong_SHIFT)) & (unsigned long) PyLong_MASK));
        } else
#endif
            unequal = (size != 1) || (((unsigned long) digits[0]) != (uintval & (unsigned long) PyLong_MASK));
        if (unequal == 0) Py_RETURN_TRUE; else Py_RETURN_FALSE;
    }
    #endif
    if (PyFloat_CheckExact(op1)) {
        const long b = intval;
        double a = PyFloat_AS_DOUBLE(op1);
        if ((double)a == (double)b) Py_RETURN_TRUE; else Py_RETURN_FALSE;
    }
    return (
        PyObject_RichCompare(op1, op2, Py_EQ));
}

/* py_dict_values */
static CYTHON_INLINE PyObject* __Pyx_PyDict_Values(PyObject* d) {
    if (PY_MAJOR_VERSION >= 3)
        return __Pyx_CallUnboundCMethod0(&__pyx_umethod_PyDict_Type_values, d);
    else
        return PyDict_Values(d);
}

/* None */
static CYTHON_INLINE long __Pyx_div_long(long a, long b) {
    long q = a / b;
    long r = a - q*b;
    q -= ((r != 0) & ((r ^ b) < 0));
    return q;
}

/* IsLittleEndian */
static CYTHON_INLINE int __Pyx_Is_Little_Endian(void)
{
  union {
    uint32_t u32;
    uint8_t u8[4];
  } S;
  S.u32 = 0x01020304;
  return S.u8[0] == 4;
}

/* BufferFormatCheck */
static void __Pyx_BufFmt_Init(__Pyx_BufFmt_Context* ctx,
                              __Pyx_BufFmt_StackElem* stack,
                              __Pyx_TypeInfo* type) {
  stack[0].field = &ctx->root;
  stack[0].parent_offset = 0;
  ctx->root.type = type;
  ctx->root.name = "buffer dtype";
  ctx->root.offset = 0;
  ctx->head = stack;
  ctx->head->field = &ctx->root;
  ctx->fmt_offset = 0;
  ctx->head->parent_offset = 0;
  ctx->new_packmode = '@';
  ctx->enc_packmode = '@';
  ctx->new_count = 1;
  ctx->enc_count = 0;
  ctx->enc_type = 0;
  ctx->is_complex = 0;
  ctx->is_valid_array = 0;
  ctx->struct_alignment = 0;
  while (type->typegroup == 'S') {
    ++ctx->head;
    ctx->head->field = type->fields;
    ctx->head->parent_offset = 0;
    type = type->fields->type;
  }
}
static int __Pyx_BufFmt_ParseNumber(const char** ts) {
    int count;
    const char* t = *ts;
    if (*t < '0' || *t > '9') {
      return -1;
    } else {
        count = *t++ - '0';
        while (*t >= '0' && *t <= '9') {
            count *= 10;
            count += *t++ - '0';
        }
    }
    *ts = t;
    return count;
}
static int __Pyx_BufFmt_ExpectNumber(const char **ts) {
    int number = __Pyx_BufFmt_ParseNumber(ts);
    if (number == -1)
        PyErr_Format(PyExc_ValueError,\
                     "Does not understand character buffer dtype format string ('%c')", **ts);
    return number;
}
static void __Pyx_BufFmt_RaiseUnexpectedChar(char ch) {
  PyErr_Format(PyExc_ValueError,
               "Unexpected format string character: '%c'", ch);
}
static const char* __Pyx_BufFmt_DescribeTypeChar(char ch, int is_complex) {
  switch (ch) {
    case 'c': return "'char'";
    case 'b': return "'signed char'";
    case 'B': return "'unsigned char'";
    case 'h': return "'short'";
    case 'H': return "'unsigned short'";
    case 'i': return "'int'";
    case 'I': return "'unsigned int'";
    case 'l': return "'long'";
    case 'L': return "'unsigned long'";
    case 'q': return "'long long'";
    case 'Q': return "'unsigned long long'";
    case 'f': return (is_complex ? "'complex float'" : "'float'");
    case 'd': return (is_complex ? "'complex double'" : "'double'");
    case 'g': return (is_complex ? "'complex long double'" : "'long double'");
    case 'T': return "a struct";
    case 'O': return "Python object";
    case 'P': return "a pointer";
    case 's': case 'p': return "a string";
    case 0: return "end";
    default: return "unparseable format string";
  }
}
static size_t __Pyx_BufFmt_TypeCharToStandardSize(char ch, int is_complex) {
  switch (ch) {
    case '?': case 'c': case 'b': case 'B': case 's': case 'p': return 1;
    case 'h': case 'H': return 2;
    case 'i': case 'I': case 'l': case 'L': return 4;
    case 'q': case 'Q': return 8;
    case 'f': return (is_complex ? 8 : 4);
    case 'd': return (is_complex ? 16 : 8);
    case 'g': {
      PyErr_SetString(PyExc_ValueError, "Python does not define a standard format string size for long double ('g')..");
      return 0;
    }
    case 'O': case 'P': return sizeof(void*);
    default:
      __Pyx_BufFmt_RaiseUnexpectedChar(ch);
      return 0;
    }
}
static size_t __Pyx_BufFmt_TypeCharToNativeSize(char ch, int is_complex) {
  switch (ch) {
    case 'c': case 'b': case 'B': case 's': case 'p': return 1;
    case 'h': case 'H': return sizeof(short);
    case 'i': case 'I': return sizeof(int);
    case 'l': case 'L': return sizeof(long);
    #ifdef HAVE_LONG_LONG
    case 'q': case 'Q': return sizeof(PY_LONG_LONG);
    #endif
    case 'f': return sizeof(float) * (is_complex ? 2 : 1);
    case 'd': return sizeof(double) * (is_complex ? 2 : 1);
    case 'g': return sizeof(long double) * (is_complex ? 2 : 1);
    case 'O': case 'P': return sizeof(void*);
    default: {
      __Pyx_BufFmt_RaiseUnexpectedChar(ch);
      return 0;
    }
  }
}
typedef struct { char c; short x; } __Pyx_st_short;
typedef struct { char c; int x; } __Pyx_st_int;
typedef struct { char c; long x; } __Pyx_st_long;
typedef struct { char c; float x; } __Pyx_st_float;
typedef struct { char c; double x; } __Pyx_st_double;
typedef struct { char c; long double x; } __Pyx_st_longdouble;
typedef struct { char c; void *x; } __Pyx_st_void_p;
#ifdef HAVE_LONG_LONG
typedef struct { char c; PY_LONG_LONG x; } __Pyx_st_longlong;
#endif
static size_t __Pyx_BufFmt_TypeCharToAlignment(char ch, CYTHON_UNUSED int is_complex) {
  switch (ch) {
    case '?': case 'c': case 'b': case 'B': case 's': case 'p': return 1;
    case 'h': case 'H': return sizeof(__Pyx_st_short) - sizeof(short);
    case 'i': case 'I': return sizeof(__Pyx_st_int) - sizeof(int);
    case 'l': case 'L': return sizeof(__Pyx_st_long) - sizeof(long);
#ifdef HAVE_LONG_LONG
    case 'q': case 'Q': return sizeof(__Pyx_st_longlong) - sizeof(PY_LONG_LONG);
#endif
    case 'f': return sizeof(__Pyx_st_float) - sizeof(float);
    case 'd': return sizeof(__Pyx_st_double) - sizeof(double);
    case 'g': return sizeof(__Pyx_st_longdouble) - sizeof(long double);
    case 'P': case 'O': return sizeof(__Pyx_st_void_p) - sizeof(void*);
    default:
      __Pyx_BufFmt_RaiseUnexpectedChar(ch);
      return 0;
    }
}
/* These are for computing the padding at the end of the struct to align
   on the first member of the struct. This will probably the same as above,
   but we don't have any guarantees.
 */
typedef struct { short x; char c; } __Pyx_pad_short;
typedef struct { int x; char c; } __Pyx_pad_int;
typedef struct { long x; char c; } __Pyx_pad_long;
typedef struct { float x; char c; } __Pyx_pad_float;
typedef struct { double x; char c; } __Pyx_pad_double;
typedef struct { long double x; char c; } __Pyx_pad_longdouble;
typedef struct { void *x; char c; } __Pyx_pad_void_p;
#ifdef HAVE_LONG_LONG
typedef struct { PY_LONG_LONG x; char c; } __Pyx_pad_longlong;
#endif
static size_t __Pyx_BufFmt_TypeCharToPadding(char ch, CYTHON_UNUSED int is_complex) {
  switch (ch) {
    case '?': case 'c': case 'b': case 'B': case 's': case 'p': return 1;
    case 'h': case 'H': return sizeof(__Pyx_pad_short) - sizeof(short);
    case 'i': case 'I': return sizeof(__Pyx_pad_int) - sizeof(int);
    case 'l': case 'L': return sizeof(__Pyx_pad_long) - sizeof(long);
#ifdef HAVE_LONG_LONG
    case 'q': case 'Q': return sizeof(__Pyx_pad_longlong) - sizeof(PY_LONG_LONG);
#endif
    case 'f': return sizeof(__Pyx_pad_float) - sizeof(float);
    case 'd': return sizeof(__Pyx_pad_double) - sizeof(double);
    case 'g': return sizeof(__Pyx_pad_longdouble) - sizeof(long double);
    case 'P': case 'O': return sizeof(__Pyx_pad_void_p) - sizeof(void*);
    default:
      __Pyx_BufFmt_RaiseUnexpectedChar(ch);
      return 0;
    }
}
static char __Pyx_BufFmt_TypeCharToGroup(char ch, int is_complex) {
  switch (ch) {
    case 'c':
        return 'H';
    case 'b': case 'h': case 'i':
    case 'l': case 'q': case 's': case 'p':
        return 'I';
    case 'B': case 'H': case 'I': case 'L': case 'Q':
        return 'U';
    case 'f': case 'd': case 'g':
        return (is_complex ? 'C' : 'R');
    case 'O':
        return 'O';
    case 'P':
        return 'P';
    default: {
      __Pyx_BufFmt_RaiseUnexpectedChar(ch);
      return 0;
    }
  }
}
static void __Pyx_BufFmt_RaiseExpected(__Pyx_BufFmt_Context* ctx) {
  if (ctx->head == NULL || ctx->head->field == &ctx->root) {
    const char* expected;
    const char* quote;
    if (ctx->head == NULL) {
      expected = "end";
      quote = "";
    } else {
      expected = ctx->head->field->type->name;
      quote = "'";
    }
    PyErr_Format(PyExc_ValueError,
                 "Buffer dtype mismatch, expected %s%s%s but got %s",
                 quote, expected, quote,
                 __Pyx_BufFmt_DescribeTypeChar(ctx->enc_type, ctx->is_complex));
  } else {
    __Pyx_StructField* field = ctx->head->field;
    __Pyx_StructField* parent = (ctx->head - 1)->field;
    PyErr_Format(PyExc_ValueError,
                 "Buffer dtype mismatch, expected '%s' but got %s in '%s.%s'",
                 field->type->name, __Pyx_BufFmt_DescribeTypeChar(ctx->enc_type, ctx->is_complex),
                 parent->type->name, field->name);
  }
}
static int __Pyx_BufFmt_ProcessTypeChunk(__Pyx_BufFmt_Context* ctx) {
  char group;
  size_t size, offset, arraysize = 1;
  if (ctx->enc_type == 0) return 0;
  if (ctx->head->field->type->arraysize[0]) {
    int i, ndim = 0;
    if (ctx->enc_type == 's' || ctx->enc_type == 'p') {
        ctx->is_valid_array = ctx->head->field->type->ndim == 1;
        ndim = 1;
        if (ctx->enc_count != ctx->head->field->type->arraysize[0]) {
            PyErr_Format(PyExc_ValueError,
                         "Expected a dimension of size %zu, got %zu",
                         ctx->head->field->type->arraysize[0], ctx->enc_count);
            return -1;
        }
    }
    if (!ctx->is_valid_array) {
      PyErr_Format(PyExc_ValueError, "Expected %d dimensions, got %d",
                   ctx->head->field->type->ndim, ndim);
      return -1;
    }
    for (i = 0; i < ctx->head->field->type->ndim; i++) {
      arraysize *= ctx->head->field->type->arraysize[i];
    }
    ctx->is_valid_array = 0;
    ctx->enc_count = 1;
  }
  group = __Pyx_BufFmt_TypeCharToGroup(ctx->enc_type, ctx->is_complex);
  do {
    __Pyx_StructField* field = ctx->head->field;
    __Pyx_TypeInfo* type = field->type;
    if (ctx->enc_packmode == '@' || ctx->enc_packmode == '^') {
      size = __Pyx_BufFmt_TypeCharToNativeSize(ctx->enc_type, ctx->is_complex);
    } else {
      size = __Pyx_BufFmt_TypeCharToStandardSize(ctx->enc_type, ctx->is_complex);
    }
    if (ctx->enc_packmode == '@') {
      size_t align_at = __Pyx_BufFmt_TypeCharToAlignment(ctx->enc_type, ctx->is_complex);
      size_t align_mod_offset;
      if (align_at == 0) return -1;
      align_mod_offset = ctx->fmt_offset % align_at;
      if (align_mod_offset > 0) ctx->fmt_offset += align_at - align_mod_offset;
      if (ctx->struct_alignment == 0)
          ctx->struct_alignment = __Pyx_BufFmt_TypeCharToPadding(ctx->enc_type,
                                                                 ctx->is_complex);
    }
    if (type->size != size || type->typegroup != group) {
      if (type->typegroup == 'C' && type->fields != NULL) {
        size_t parent_offset = ctx->head->parent_offset + field->offset;
        ++ctx->head;
        ctx->head->field = type->fields;
        ctx->head->parent_offset = parent_offset;
        continue;
      }
      if ((type->typegroup == 'H' || group == 'H') && type->size == size) {
      } else {
          __Pyx_BufFmt_RaiseExpected(ctx);
          return -1;
      }
    }
    offset = ctx->head->parent_offset + field->offset;
    if (ctx->fmt_offset != offset) {
      PyErr_Format(PyExc_ValueError,
                   "Buffer dtype mismatch; next field is at offset %" CYTHON_FORMAT_SSIZE_T "d but %" CYTHON_FORMAT_SSIZE_T "d expected",
                   (Py_ssize_t)ctx->fmt_offset, (Py_ssize_t)offset);
      return -1;
    }
    ctx->fmt_offset += size;
    if (arraysize)
      ctx->fmt_offset += (arraysize - 1) * size;
    --ctx->enc_count;
    while (1) {
      if (field == &ctx->root) {
        ctx->head = NULL;
        if (ctx->enc_count != 0) {
          __Pyx_BufFmt_RaiseExpected(ctx);
          return -1;
        }
        break;
      }
      ctx->head->field = ++field;
      if (field->type == NULL) {
        --ctx->head;
        field = ctx->head->field;
        continue;
      } else if (field->type->typegroup == 'S') {
        size_t parent_offset = ctx->head->parent_offset + field->offset;
        if (field->type->fields->type == NULL) continue;
        field = field->type->fields;
        ++ctx->head;
        ctx->head->field = field;
        ctx->head->parent_offset = parent_offset;
        break;
      } else {
        break;
      }
    }
  } while (ctx->enc_count);
  ctx->enc_type = 0;
  ctx->is_complex = 0;
  return 0;
}
static PyObject *
__pyx_buffmt_parse_array(__Pyx_BufFmt_Context* ctx, const char** tsp)
{
    const char *ts = *tsp;
    int i = 0, number;
    int ndim = ctx->head->field->type->ndim;
;
    ++ts;
    if (ctx->new_count != 1) {
        PyErr_SetString(PyExc_ValueError,
                        "Cannot handle repeated arrays in format string");
        return NULL;
    }
    if (__Pyx_BufFmt_ProcessTypeChunk(ctx) == -1) return NULL;
    while (*ts && *ts != ')') {
        switch (*ts) {
            case ' ': case '\f': case '\r': case '\n': case '\t': case '\v':  continue;
            default:  break;
        }
        number = __Pyx_BufFmt_ExpectNumber(&ts);
        if (number == -1) return NULL;
        if (i < ndim && (size_t) number != ctx->head->field->type->arraysize[i])
            return PyErr_Format(PyExc_ValueError,
                        "Expected a dimension of size %zu, got %d",
                        ctx->head->field->type->arraysize[i], number);
        if (*ts != ',' && *ts != ')')
            return PyErr_Format(PyExc_ValueError,
                                "Expected a comma in format string, got '%c'", *ts);
        if (*ts == ',') ts++;
        i++;
    }
    if (i != ndim)
        return PyErr_Format(PyExc_ValueError, "Expected %d dimension(s), got %d",
                            ctx->head->field->type->ndim, i);
    if (!*ts) {
        PyErr_SetString(PyExc_ValueError,
                        "Unexpected end of format string, expected ')'");
        return NULL;
    }
    ctx->is_valid_array = 1;
    ctx->new_count = 1;
    *tsp = ++ts;
    return Py_None;
}
static const char* __Pyx_BufFmt_CheckString(__Pyx_BufFmt_Context* ctx, const char* ts) {
  int got_Z = 0;
  while (1) {
    switch(*ts) {
      case 0:
        if (ctx->enc_type != 0 && ctx->head == NULL) {
          __Pyx_BufFmt_RaiseExpected(ctx);
          return NULL;
        }
        if (__Pyx_BufFmt_ProcessTypeChunk(ctx) == -1) return NULL;
        if (ctx->head != NULL) {
          __Pyx_BufFmt_RaiseExpected(ctx);
          return NULL;
        }
        return ts;
      case ' ':
      case '\r':
      case '\n':
        ++ts;
        break;
      case '<':
        if (!__Pyx_Is_Little_Endian()) {
          PyErr_SetString(PyExc_ValueError, "Little-endian buffer not supported on big-endian compiler");
          return NULL;
        }
        ctx->new_packmode = '=';
        ++ts;
        break;
      case '>':
      case '!':
        if (__Pyx_Is_Little_Endian()) {
          PyErr_SetString(PyExc_ValueError, "Big-endian buffer not supported on little-endian compiler");
          return NULL;
        }
        ctx->new_packmode = '=';
        ++ts;
        break;
      case '=':
      case '@':
      case '^':
        ctx->new_packmode = *ts++;
        break;
      case 'T':
        {
          const char* ts_after_sub;
          size_t i, struct_count = ctx->new_count;
          size_t struct_alignment = ctx->struct_alignment;
          ctx->new_count = 1;
          ++ts;
          if (*ts != '{') {
            PyErr_SetString(PyExc_ValueError, "Buffer acquisition: Expected '{' after 'T'");
            return NULL;
          }
          if (__Pyx_BufFmt_ProcessTypeChunk(ctx) == -1) return NULL;
          ctx->enc_type = 0;
          ctx->enc_count = 0;
          ctx->struct_alignment = 0;
          ++ts;
          ts_after_sub = ts;
          for (i = 0; i != struct_count; ++i) {
            ts_after_sub = __Pyx_BufFmt_CheckString(ctx, ts);
            if (!ts_after_sub) return NULL;
          }
          ts = ts_after_sub;
          if (struct_alignment) ctx->struct_alignment = struct_alignment;
        }
        break;
      case '}':
        {
          size_t alignment = ctx->struct_alignment;
          ++ts;
          if (__Pyx_BufFmt_ProcessTypeChunk(ctx) == -1) return NULL;
          ctx->enc_type = 0;
          if (alignment && ctx->fmt_offset % alignment) {
            ctx->fmt_offset += alignment - (ctx->fmt_offset % alignment);
          }
        }
        return ts;
      case 'x':
        if (__Pyx_BufFmt_ProcessTypeChunk(ctx) == -1) return NULL;
        ctx->fmt_offset += ctx->new_count;
        ctx->new_count = 1;
        ctx->enc_count = 0;
        ctx->enc_type = 0;
        ctx->enc_packmode = ctx->new_packmode;
        ++ts;
        break;
      case 'Z':
        got_Z = 1;
        ++ts;
        if (*ts != 'f' && *ts != 'd' && *ts != 'g') {
          __Pyx_BufFmt_RaiseUnexpectedChar('Z');
          return NULL;
        }
        CYTHON_FALLTHROUGH;
      case 'c': case 'b': case 'B': case 'h': case 'H': case 'i': case 'I':
      case 'l': case 'L': case 'q': case 'Q':
      case 'f': case 'd': case 'g':
      case 'O': case 'p':
        if (ctx->enc_type == *ts && got_Z == ctx->is_complex &&
            ctx->enc_packmode == ctx->new_packmode) {
          ctx->enc_count += ctx->new_count;
          ctx->new_count = 1;
          got_Z = 0;
          ++ts;
          break;
        }
        CYTHON_FALLTHROUGH;
      case 's':
        if (__Pyx_BufFmt_ProcessTypeChunk(ctx) == -1) return NULL;
        ctx->enc_count = ctx->new_count;
        ctx->enc_packmode = ctx->new_packmode;
        ctx->enc_type = *ts;
        ctx->is_complex = got_Z;
        ++ts;
        ctx->new_count = 1;
        got_Z = 0;
        break;
      case ':':
        ++ts;
        while(*ts != ':') ++ts;
        ++ts;
        break;
      case '(':
        if (!__pyx_buffmt_parse_array(ctx, &ts)) return NULL;
        break;
      default:
        {
          int number = __Pyx_BufFmt_ExpectNumber(&ts);
          if (number == -1) return NULL;
          ctx->new_count = (size_t)number;
        }
    }
  }
}

/* BufferGetAndValidate */
  static CYTHON_INLINE void __Pyx_SafeReleaseBuffer(Py_buffer* info) {
  if (unlikely(info->buf == NULL)) return;
  if (info->suboffsets == __Pyx_minusones) info->suboffsets = NULL;
  __Pyx_ReleaseBuffer(info);
}
static void __Pyx_ZeroBuffer(Py_buffer* buf) {
  buf->buf = NULL;
  buf->obj = NULL;
  buf->strides = __Pyx_zeros;
  buf->shape = __Pyx_zeros;
  buf->suboffsets = __Pyx_minusones;
}
static int __Pyx__GetBufferAndValidate(
        Py_buffer* buf, PyObject* obj,  __Pyx_TypeInfo* dtype, int flags,
        int nd, int cast, __Pyx_BufFmt_StackElem* stack)
{
  buf->buf = NULL;
  if (unlikely(__Pyx_GetBuffer(obj, buf, flags) == -1)) {
    __Pyx_ZeroBuffer(buf);
    return -1;
  }
  if (unlikely(buf->ndim != nd)) {
    PyErr_Format(PyExc_ValueError,
                 "Buffer has wrong number of dimensions (expected %d, got %d)",
                 nd, buf->ndim);
    goto fail;
  }
  if (!cast) {
    __Pyx_BufFmt_Context ctx;
    __Pyx_BufFmt_Init(&ctx, stack, dtype);
    if (!__Pyx_BufFmt_CheckString(&ctx, buf->format)) goto fail;
  }
  if (unlikely((size_t)buf->itemsize != dtype->size)) {
    PyErr_Format(PyExc_ValueError,
      "Item size of buffer (%" CYTHON_FORMAT_SSIZE_T "d byte%s) does not match size of '%s' (%" CYTHON_FORMAT_SSIZE_T "d byte%s)",
      buf->itemsize, (buf->itemsize > 1) ? "s" : "",
      dtype->name, (Py_ssize_t)dtype->size, (dtype->size > 1) ? "s" : "");
    goto fail;
  }
  if (buf->suboffsets == NULL) buf->suboffsets = __Pyx_minusones;
  return 0;
fail:;
  __Pyx_SafeReleaseBuffer(buf);
  return -1;
}

/* Import */
  static PyObject *__Pyx_Import(PyObject *name, PyObject *from_list, int level) {
    PyObject *empty_list = 0;
    PyObject *module = 0;
    PyObject *global_dict = 0;
    PyObject *empty_dict = 0;
    PyObject *list;
    #if PY_MAJOR_VERSION < 3
    PyObject *py_import;
    py_import = __Pyx_PyObject_GetAttrStr(__pyx_b, __pyx_n_s_import);
    if (!py_import)
        goto bad;
    #endif
    if (from_list)
        list = from_list;
    else {
        empty_list = PyList_New(0);
        if (!empty_list)
            goto bad;
        list = empty_list;
    }
    global_dict = PyModule_GetDict(__pyx_m);
    if (!global_dict)
        goto bad;
    empty_dict = PyDict_New();
    if (!empty_dict)
        goto bad;
    {
        #if PY_MAJOR_VERSION >= 3
        if (level == -1) {
            if (strchr(__Pyx_MODULE_NAME, '.')) {
                module = PyImport_ImportModuleLevelObject(
                    name, global_dict, empty_dict, list, 1);
                if (!module) {
                    if (!PyErr_ExceptionMatches(PyExc_ImportError))
                        goto bad;
                    PyErr_Clear();
                }
            }
            level = 0;
        }
        #endif
        if (!module) {
            #if PY_MAJOR_VERSION < 3
            PyObject *py_level = PyInt_FromLong(level);
            if (!py_level)
                goto bad;
            module = PyObject_CallFunctionObjArgs(py_import,
                name, global_dict, empty_dict, list, py_level, (PyObject *)NULL);
            Py_DECREF(py_level);
            #else
            module = PyImport_ImportModuleLevelObject(
                name, global_dict, empty_dict, list, level);
            #endif
        }
    }
bad:
    #if PY_MAJOR_VERSION < 3
    Py_XDECREF(py_import);
    #endif
    Py_XDECREF(empty_list);
    Py_XDECREF(empty_dict);
    return module;
}

/* ImportFrom */
  static PyObject* __Pyx_ImportFrom(PyObject* module, PyObject* name) {
    PyObject* value = __Pyx_PyObject_GetAttrStr(module, name);
    if (unlikely(!value) && PyErr_ExceptionMatches(PyExc_AttributeError)) {
        PyErr_Format(PyExc_ImportError,
        #if PY_MAJOR_VERSION < 3
            "cannot import name %.230s", PyString_AS_STRING(name));
        #else
            "cannot import name %S", name);
        #endif
    }
    return value;
}

/* HasAttr */
  static CYTHON_INLINE int __Pyx_HasAttr(PyObject *o, PyObject *n) {
    PyObject *r;
    if (unlikely(!__Pyx_PyBaseString_Check(n))) {
        PyErr_SetString(PyExc_TypeError,
                        "hasattr(): attribute name must be string");
        return -1;
    }
    r = __Pyx_GetAttr(o, n);
    if (unlikely(!r)) {
        PyErr_Clear();
        return 0;
    } else {
        Py_DECREF(r);
        return 1;
    }
}

/* None */
  static CYTHON_INLINE Py_ssize_t __Pyx_div_Py_ssize_t(Py_ssize_t a, Py_ssize_t b) {
    Py_ssize_t q = a / b;
    Py_ssize_t r = a - q*b;
    q -= ((r != 0) & ((r ^ b) < 0));
    return q;
}

/* decode_c_string */
  static CYTHON_INLINE PyObject* __Pyx_decode_c_string(
         const char* cstring, Py_ssize_t start, Py_ssize_t stop,
         const char* encoding, const char* errors,
         PyObject* (*decode_func)(const char *s, Py_ssize_t size, const char *errors)) {
    Py_ssize_t length;
    if (unlikely((start < 0) | (stop < 0))) {
        size_t slen = strlen(cstring);
        if (unlikely(slen > (size_t) PY_SSIZE_T_MAX)) {
            PyErr_SetString(PyExc_OverflowError,
                            "c-string too long to convert to Python");
            return NULL;
        }
        length = (Py_ssize_t) slen;
        if (start < 0) {
            start += length;
            if (start < 0)
                start = 0;
        }
        if (stop < 0)
            stop += length;
    }
    length = stop - start;
    if (unlikely(length <= 0))
        return PyUnicode_FromUnicode(NULL, 0);
    cstring += start;
    if (decode_func) {
        return decode_func(cstring, length, errors);
    } else {
        return PyUnicode_Decode(cstring, length, encoding, errors);
    }
}

/* SwapException */
  #if CYTHON_FAST_THREAD_STATE
static CYTHON_INLINE void __Pyx__ExceptionSwap(PyThreadState *tstate, PyObject **type, PyObject **value, PyObject **tb) {
    PyObject *tmp_type, *tmp_value, *tmp_tb;
    #if CYTHON_USE_EXC_INFO_STACK
    _PyErr_StackItem *exc_info = tstate->exc_info;
    tmp_type = exc_info->exc_type;
    tmp_value = exc_info->exc_value;
    tmp_tb = exc_info->exc_traceback;
    exc_info->exc_type = *type;
    exc_info->exc_value = *value;
    exc_info->exc_traceback = *tb;
    #else
    tmp_type = tstate->exc_type;
    tmp_value = tstate->exc_value;
    tmp_tb = tstate->exc_traceback;
    tstate->exc_type = *type;
    tstate->exc_value = *value;
    tstate->exc_traceback = *tb;
    #endif
    *type = tmp_type;
    *value = tmp_value;
    *tb = tmp_tb;
}
#else
static CYTHON_INLINE void __Pyx_ExceptionSwap(PyObject **type, PyObject **value, PyObject **tb) {
    PyObject *tmp_type, *tmp_value, *tmp_tb;
    PyErr_GetExcInfo(&tmp_type, &tmp_value, &tmp_tb);
    PyErr_SetExcInfo(*type, *value, *tb);
    *type = tmp_type;
    *value = tmp_value;
    *tb = tmp_tb;
}
#endif

/* FastTypeChecks */
  #if CYTHON_COMPILING_IN_CPYTHON
static int __Pyx_InBases(PyTypeObject *a, PyTypeObject *b) {
    while (a) {
        a = a->tp_base;
        if (a == b)
            return 1;
    }
    return b == &PyBaseObject_Type;
}
static CYTHON_INLINE int __Pyx_IsSubtype(PyTypeObject *a, PyTypeObject *b) {
    PyObject *mro;
    if (a == b) return 1;
    mro = a->tp_mro;
    if (likely(mro)) {
        Py_ssize_t i, n;
        n = PyTuple_GET_SIZE(mro);
        for (i = 0; i < n; i++) {
            if (PyTuple_GET_ITEM(mro, i) == (PyObject *)b)
                return 1;
        }
        return 0;
    }
    return __Pyx_InBases(a, b);
}
#if PY_MAJOR_VERSION == 2
static int __Pyx_inner_PyErr_GivenExceptionMatches2(PyObject *err, PyObject* exc_type1, PyObject* exc_type2) {
    PyObject *exception, *value, *tb;
    int res;
    __Pyx_PyThreadState_declare
    __Pyx_PyThreadState_assign
    __Pyx_ErrFetch(&exception, &value, &tb);
    res = exc_type1 ? PyObject_IsSubclass(err, exc_type1) : 0;
    if (unlikely(res == -1)) {
        PyErr_WriteUnraisable(err);
        res = 0;
    }
    if (!res) {
        res = PyObject_IsSubclass(err, exc_type2);
        if (unlikely(res == -1)) {
            PyErr_WriteUnraisable(err);
            res = 0;
        }
    }
    __Pyx_ErrRestore(exception, value, tb);
    return res;
}
#else
static CYTHON_INLINE int __Pyx_inner_PyErr_GivenExceptionMatches2(PyObject *err, PyObject* exc_type1, PyObject *exc_type2) {
    int res = exc_type1 ? __Pyx_IsSubtype((PyTypeObject*)err, (PyTypeObject*)exc_type1) : 0;
    if (!res) {
        res = __Pyx_IsSubtype((PyTypeObject*)err, (PyTypeObject*)exc_type2);
    }
    return res;
}
#endif
static int __Pyx_PyErr_GivenExceptionMatchesTuple(PyObject *exc_type, PyObject *tuple) {
    Py_ssize_t i, n;
    assert(PyExceptionClass_Check(exc_type));
    n = PyTuple_GET_SIZE(tuple);
#if PY_MAJOR_VERSION >= 3
    for (i=0; i<n; i++) {
        if (exc_type == PyTuple_GET_ITEM(tuple, i)) return 1;
    }
#endif
    for (i=0; i<n; i++) {
        PyObject *t = PyTuple_GET_ITEM(tuple, i);
        #if PY_MAJOR_VERSION < 3
        if (likely(exc_type == t)) return 1;
        #endif
        if (likely(PyExceptionClass_Check(t))) {
            if (__Pyx_inner_PyErr_GivenExceptionMatches2(exc_type, NULL, t)) return 1;
        } else {
        }
    }
    return 0;
}
static CYTHON_INLINE int __Pyx_PyErr_GivenExceptionMatches(PyObject *err, PyObject* exc_type) {
    if (likely(err == exc_type)) return 1;
    if (likely(PyExceptionClass_Check(err))) {
        if (likely(PyExceptionClass_Check(exc_type))) {
            return __Pyx_inner_PyErr_GivenExceptionMatches2(err, NULL, exc_type);
        } else if (likely(PyTuple_Check(exc_type))) {
            return __Pyx_PyErr_GivenExceptionMatchesTuple(err, exc_type);
        } else {
        }
    }
    return PyErr_GivenExceptionMatches(err, exc_type);
}
static CYTHON_INLINE int __Pyx_PyErr_GivenExceptionMatches2(PyObject *err, PyObject *exc_type1, PyObject *exc_type2) {
    assert(PyExceptionClass_Check(exc_type1));
    assert(PyExceptionClass_Check(exc_type2));
    if (likely(err == exc_type1 || err == exc_type2)) return 1;
    if (likely(PyExceptionClass_Check(err))) {
        return __Pyx_inner_PyErr_GivenExceptionMatches2(err, exc_type1, exc_type2);
    }
    return (PyErr_GivenExceptionMatches(err, exc_type1) || PyErr_GivenExceptionMatches(err, exc_type2));
}
#endif

/* CallNextTpTraverse */
  static int __Pyx_call_next_tp_traverse(PyObject* obj, visitproc v, void *a, traverseproc current_tp_traverse) {
    PyTypeObject* type = Py_TYPE(obj);
    while (type && type->tp_traverse != current_tp_traverse)
        type = type->tp_base;
    while (type && type->tp_traverse == current_tp_traverse)
        type = type->tp_base;
    if (type && type->tp_traverse)
        return type->tp_traverse(obj, v, a);
    return 0;
}

/* CallNextTpClear */
  static void __Pyx_call_next_tp_clear(PyObject* obj, inquiry current_tp_clear) {
    PyTypeObject* type = Py_TYPE(obj);
    while (type && type->tp_clear != current_tp_clear)
        type = type->tp_base;
    while (type && type->tp_clear == current_tp_clear)
        type = type->tp_base;
    if (type && type->tp_clear)
        type->tp_clear(obj);
}

/* PyObject_GenericGetAttrNoDict */
  #if CYTHON_USE_TYPE_SLOTS && CYTHON_USE_PYTYPE_LOOKUP && PY_VERSION_HEX < 0x03070000
static PyObject *__Pyx_RaiseGenericGetAttributeError(PyTypeObject *tp, PyObject *attr_name) {
    PyErr_Format(PyExc_AttributeError,
#if PY_MAJOR_VERSION >= 3
                 "'%.50s' object has no attribute '%U'",
                 tp->tp_name, attr_name);
#else
                 "'%.50s' object has no attribute '%.400s'",
                 tp->tp_name, PyString_AS_STRING(attr_name));
#endif
    return NULL;
}
static CYTHON_INLINE PyObject* __Pyx_PyObject_GenericGetAttrNoDict(PyObject* obj, PyObject* attr_name) {
    PyObject *descr;
    PyTypeObject *tp = Py_TYPE(obj);
    if (unlikely(!PyString_Check(attr_name))) {
        return PyObject_GenericGetAttr(obj, attr_name);
    }
    assert(!tp->tp_dictoffset);
    descr = _PyType_Lookup(tp, attr_name);
    if (unlikely(!descr)) {
        return __Pyx_RaiseGenericGetAttributeError(tp, attr_name);
    }
    Py_INCREF(descr);
    #if PY_MAJOR_VERSION < 3
    if (likely(PyType_HasFeature(Py_TYPE(descr), Py_TPFLAGS_HAVE_CLASS)))
    #endif
    {
        descrgetfunc f = Py_TYPE(descr)->tp_descr_get;
        if (unlikely(f)) {
            PyObject *res = f(descr, obj, (PyObject *)tp);
            Py_DECREF(descr);
            return res;
        }
    }
    return descr;
}
#endif

/* PyObject_GenericGetAttr */
  #if CYTHON_USE_TYPE_SLOTS && CYTHON_USE_PYTYPE_LOOKUP && PY_VERSION_HEX < 0x03070000
static PyObject* __Pyx_PyObject_GenericGetAttr(PyObject* obj, PyObject* attr_name) {
    if (unlikely(Py_TYPE(obj)->tp_dictoffset)) {
        return PyObject_GenericGetAttr(obj, attr_name);
    }
    return __Pyx_PyObject_GenericGetAttrNoDict(obj, attr_name);
}
#endif

/* SetVTable */
  static int __Pyx_SetVtable(PyObject *dict, void *vtable) {
#if PY_VERSION_HEX >= 0x02070000
    PyObject *ob = PyCapsule_New(vtable, 0, 0);
#else
    PyObject *ob = PyCObject_FromVoidPtr(vtable, 0);
#endif
    if (!ob)
        goto bad;
    if (PyDict_SetItem(dict, __pyx_n_s_pyx_vtable, ob) < 0)
        goto bad;
    Py_DECREF(ob);
    return 0;
bad:
    Py_XDECREF(ob);
    return -1;
}

/* SetupReduce */
  static int __Pyx_setup_reduce_is_named(PyObject* meth, PyObject* name) {
  int ret;
  PyObject *name_attr;
  name_attr = __Pyx_PyObject_GetAttrStr(meth, __pyx_n_s_name_2);
  if (likely(name_attr)) {
      ret = PyObject_RichCompareBool(name_attr, name, Py_EQ);
  } else {
      ret = -1;
  }
  if (unlikely(ret < 0)) {
      PyErr_Clear();
      ret = 0;
  }
  Py_XDECREF(name_attr);
  return ret;
}
static int __Pyx_setup_reduce(PyObject* type_obj) {
    int ret = 0;
    PyObject *object_reduce = NULL;
    PyObject *object_reduce_ex = NULL;
    PyObject *reduce = NULL;
    PyObject *reduce_ex = NULL;
    PyObject *reduce_cython = NULL;
    PyObject *setstate = NULL;
    PyObject *setstate_cython = NULL;
#if CYTHON_USE_PYTYPE_LOOKUP
    if (_PyType_Lookup((PyTypeObject*)type_obj, __pyx_n_s_getstate)) goto GOOD;
#else
    if (PyObject_HasAttr(type_obj, __pyx_n_s_getstate)) goto GOOD;
#endif
#if CYTHON_USE_PYTYPE_LOOKUP
    object_reduce_ex = _PyType_Lookup(&PyBaseObject_Type, __pyx_n_s_reduce_ex); if (!object_reduce_ex) goto BAD;
#else
    object_reduce_ex = __Pyx_PyObject_GetAttrStr((PyObject*)&PyBaseObject_Type, __pyx_n_s_reduce_ex); if (!object_reduce_ex) goto BAD;
#endif
    reduce_ex = __Pyx_PyObject_GetAttrStr(type_obj, __pyx_n_s_reduce_ex); if (unlikely(!reduce_ex)) goto BAD;
    if (reduce_ex == object_reduce_ex) {
#if CYTHON_USE_PYTYPE_LOOKUP
        object_reduce = _PyType_Lookup(&PyBaseObject_Type, __pyx_n_s_reduce); if (!object_reduce) goto BAD;
#else
        object_reduce = __Pyx_PyObject_GetAttrStr((PyObject*)&PyBaseObject_Type, __pyx_n_s_reduce); if (!object_reduce) goto BAD;
#endif
        reduce = __Pyx_PyObject_GetAttrStr(type_obj, __pyx_n_s_reduce); if (unlikely(!reduce)) goto BAD;
        if (reduce == object_reduce || __Pyx_setup_reduce_is_named(reduce, __pyx_n_s_reduce_cython)) {
            reduce_cython = __Pyx_PyObject_GetAttrStr(type_obj, __pyx_n_s_reduce_cython); if (unlikely(!reduce_cython)) goto BAD;
            ret = PyDict_SetItem(((PyTypeObject*)type_obj)->tp_dict, __pyx_n_s_reduce, reduce_cython); if (unlikely(ret < 0)) goto BAD;
            ret = PyDict_DelItem(((PyTypeObject*)type_obj)->tp_dict, __pyx_n_s_reduce_cython); if (unlikely(ret < 0)) goto BAD;
            setstate = __Pyx_PyObject_GetAttrStr(type_obj, __pyx_n_s_setstate);
            if (!setstate) PyErr_Clear();
            if (!setstate || __Pyx_setup_reduce_is_named(setstate, __pyx_n_s_setstate_cython)) {
                setstate_cython = __Pyx_PyObject_GetAttrStr(type_obj, __pyx_n_s_setstate_cython); if (unlikely(!setstate_cython)) goto BAD;
                ret = PyDict_SetItem(((PyTypeObject*)type_obj)->tp_dict, __pyx_n_s_setstate, setstate_cython); if (unlikely(ret < 0)) goto BAD;
                ret = PyDict_DelItem(((PyTypeObject*)type_obj)->tp_dict, __pyx_n_s_setstate_cython); if (unlikely(ret < 0)) goto BAD;
            }
            PyType_Modified((PyTypeObject*)type_obj);
        }
    }
    goto GOOD;
BAD:
    if (!PyErr_Occurred())
        PyErr_Format(PyExc_RuntimeError, "Unable to initialize pickling for %s", ((PyTypeObject*)type_obj)->tp_name);
    ret = -1;
GOOD:
#if !CYTHON_USE_PYTYPE_LOOKUP
    Py_XDECREF(object_reduce);
    Py_XDECREF(object_reduce_ex);
#endif
    Py_XDECREF(reduce);
    Py_XDECREF(reduce_ex);
    Py_XDECREF(reduce_cython);
    Py_XDECREF(setstate);
    Py_XDECREF(setstate_cython);
    return ret;
}

/* TypeImport */
  #ifndef __PYX_HAVE_RT_ImportType
#define __PYX_HAVE_RT_ImportType
static PyTypeObject *__Pyx_ImportType(PyObject *module, const char *module_name, const char *class_name,
    size_t size, enum __Pyx_ImportType_CheckSize check_size)
{
    PyObject *result = 0;
    char warning[200];
    Py_ssize_t basicsize;
#ifdef Py_LIMITED_API
    PyObject *py_basicsize;
#endif
    result = PyObject_GetAttrString(module, class_name);
    if (!result)
        goto bad;
    if (!PyType_Check(result)) {
        PyErr_Format(PyExc_TypeError,
            "%.200s.%.200s is not a type object",
            module_name, class_name);
        goto bad;
    }
#ifndef Py_LIMITED_API
    basicsize = ((PyTypeObject *)result)->tp_basicsize;
#else
    py_basicsize = PyObject_GetAttrString(result, "__basicsize__");
    if (!py_basicsize)
        goto bad;
    basicsize = PyLong_AsSsize_t(py_basicsize);
    Py_DECREF(py_basicsize);
    py_basicsize = 0;
    if (basicsize == (Py_ssize_t)-1 && PyErr_Occurred())
        goto bad;
#endif
    if ((size_t)basicsize < size) {
        PyErr_Format(PyExc_ValueError,
            "%.200s.%.200s size changed, may indicate binary incompatibility. "
            "Expected %zd from C header, got %zd from PyObject",
            module_name, class_name, size, basicsize);
        goto bad;
    }
    if (check_size == __Pyx_ImportType_CheckSize_Error && (size_t)basicsize != size) {
        PyErr_Format(PyExc_ValueError,
            "%.200s.%.200s size changed, may indicate binary incompatibility. "
            "Expected %zd from C header, got %zd from PyObject",
            module_name, class_name, size, basicsize);
        goto bad;
    }
    else if (check_size == __Pyx_ImportType_CheckSize_Warn && (size_t)basicsize > size) {
        PyOS_snprintf(warning, sizeof(warning),
            "%s.%s size changed, may indicate binary incompatibility. "
            "Expected %zd from C header, got %zd from PyObject",
            module_name, class_name, size, basicsize);
        if (PyErr_WarnEx(NULL, warning, 0) < 0) goto bad;
    }
    return (PyTypeObject *)result;
bad:
    Py_XDECREF(result);
    return NULL;
}
#endif

/* CLineInTraceback */
  #ifndef CYTHON_CLINE_IN_TRACEBACK
static int __Pyx_CLineForTraceback(PyThreadState *tstate, int c_line) {
    PyObject *use_cline;
    PyObject *ptype, *pvalue, *ptraceback;
#if CYTHON_COMPILING_IN_CPYTHON
    PyObject **cython_runtime_dict;
#endif
    if (unlikely(!__pyx_cython_runtime)) {
        return c_line;
    }
    __Pyx_ErrFetchInState(tstate, &ptype, &pvalue, &ptraceback);
#if CYTHON_COMPILING_IN_CPYTHON
    cython_runtime_dict = _PyObject_GetDictPtr(__pyx_cython_runtime);
    if (likely(cython_runtime_dict)) {
        __PYX_PY_DICT_LOOKUP_IF_MODIFIED(
            use_cline, *cython_runtime_dict,
            __Pyx_PyDict_GetItemStr(*cython_runtime_dict, __pyx_n_s_cline_in_traceback))
    } else
#endif
    {
      PyObject *use_cline_obj = __Pyx_PyObject_GetAttrStr(__pyx_cython_runtime, __pyx_n_s_cline_in_traceback);
      if (use_cline_obj) {
        use_cline = PyObject_Not(use_cline_obj) ? Py_False : Py_True;
        Py_DECREF(use_cline_obj);
      } else {
        PyErr_Clear();
        use_cline = NULL;
      }
    }
    if (!use_cline) {
        c_line = 0;
        PyObject_SetAttr(__pyx_cython_runtime, __pyx_n_s_cline_in_traceback, Py_False);
    }
    else if (use_cline == Py_False || (use_cline != Py_True && PyObject_Not(use_cline) != 0)) {
        c_line = 0;
    }
    __Pyx_ErrRestoreInState(tstate, ptype, pvalue, ptraceback);
    return c_line;
}
#endif

/* CodeObjectCache */
  static int __pyx_bisect_code_objects(__Pyx_CodeObjectCacheEntry* entries, int count, int code_line) {
    int start = 0, mid = 0, end = count - 1;
    if (end >= 0 && code_line > entries[end].code_line) {
        return count;
    }
    while (start < end) {
        mid = start + (end - start) / 2;
        if (code_line < entries[mid].code_line) {
            end = mid;
        } else if (code_line > entries[mid].code_line) {
             start = mid + 1;
        } else {
            return mid;
        }
    }
    if (code_line <= entries[mid].code_line) {
        return mid;
    } else {
        return mid + 1;
    }
}
static PyCodeObject *__pyx_find_code_object(int code_line) {
    PyCodeObject* code_object;
    int pos;
    if (unlikely(!code_line) || unlikely(!__pyx_code_cache.entries)) {
        return NULL;
    }
    pos = __pyx_bisect_code_objects(__pyx_code_cache.entries, __pyx_code_cache.count, code_line);
    if (unlikely(pos >= __pyx_code_cache.count) || unlikely(__pyx_code_cache.entries[pos].code_line != code_line)) {
        return NULL;
    }
    code_object = __pyx_code_cache.entries[pos].code_object;
    Py_INCREF(code_object);
    return code_object;
}
static void __pyx_insert_code_object(int code_line, PyCodeObject* code_object) {
    int pos, i;
    __Pyx_CodeObjectCacheEntry* entries = __pyx_code_cache.entries;
    if (unlikely(!code_line)) {
        return;
    }
    if (unlikely(!entries)) {
        entries = (__Pyx_CodeObjectCacheEntry*)PyMem_Malloc(64*sizeof(__Pyx_CodeObjectCacheEntry));
        if (likely(entries)) {
            __pyx_code_cache.entries = entries;
            __pyx_code_cache.max_count = 64;
            __pyx_code_cache.count = 1;
            entries[0].code_line = code_line;
            entries[0].code_object = code_object;
            Py_INCREF(code_object);
        }
        return;
    }
    pos = __pyx_bisect_code_objects(__pyx_code_cache.entries, __pyx_code_cache.count, code_line);
    if ((pos < __pyx_code_cache.count) && unlikely(__pyx_code_cache.entries[pos].code_line == code_line)) {
        PyCodeObject* tmp = entries[pos].code_object;
        entries[pos].code_object = code_object;
        Py_DECREF(tmp);
        return;
    }
    if (__pyx_code_cache.count == __pyx_code_cache.max_count) {
        int new_max = __pyx_code_cache.max_count + 64;
        entries = (__Pyx_CodeObjectCacheEntry*)PyMem_Realloc(
            __pyx_code_cache.entries, (size_t)new_max*sizeof(__Pyx_CodeObjectCacheEntry));
        if (unlikely(!entries)) {
            return;
        }
        __pyx_code_cache.entries = entries;
        __pyx_code_cache.max_count = new_max;
    }
    for (i=__pyx_code_cache.count; i>pos; i--) {
        entries[i] = entries[i-1];
    }
    entries[pos].code_line = code_line;
    entries[pos].code_object = code_object;
    __pyx_code_cache.count++;
    Py_INCREF(code_object);
}

/* AddTraceback */
  #include "compile.h"
#include "frameobject.h"
#include "traceback.h"
static PyCodeObject* __Pyx_CreateCodeObjectForTraceback(
            const char *funcname, int c_line,
            int py_line, const char *filename) {
    PyCodeObject *py_code = 0;
    PyObject *py_srcfile = 0;
    PyObject *py_funcname = 0;
    #if PY_MAJOR_VERSION < 3
    py_srcfile = PyString_FromString(filename);
    #else
    py_srcfile = PyUnicode_FromString(filename);
    #endif
    if (!py_srcfile) goto bad;
    if (c_line) {
        #if PY_MAJOR_VERSION < 3
        py_funcname = PyString_FromFormat( "%s (%s:%d)", funcname, __pyx_cfilenm, c_line);
        #else
        py_funcname = PyUnicode_FromFormat( "%s (%s:%d)", funcname, __pyx_cfilenm, c_line);
        #endif
    }
    else {
        #if PY_MAJOR_VERSION < 3
        py_funcname = PyString_FromString(funcname);
        #else
        py_funcname = PyUnicode_FromString(funcname);
        #endif
    }
    if (!py_funcname) goto bad;
    py_code = __Pyx_PyCode_New(
        0,
        0,
        0,
        0,
        0,
        __pyx_empty_bytes, /*PyObject *code,*/
        __pyx_empty_tuple, /*PyObject *consts,*/
        __pyx_empty_tuple, /*PyObject *names,*/
        __pyx_empty_tuple, /*PyObject *varnames,*/
        __pyx_empty_tuple, /*PyObject *freevars,*/
        __pyx_empty_tuple, /*PyObject *cellvars,*/
        py_srcfile,   /*PyObject *filename,*/
        py_funcname,  /*PyObject *name,*/
        py_line,
        __pyx_empty_bytes  /*PyObject *lnotab*/
    );
    Py_DECREF(py_srcfile);
    Py_DECREF(py_funcname);
    return py_code;
bad:
    Py_XDECREF(py_srcfile);
    Py_XDECREF(py_funcname);
    return NULL;
}
static void __Pyx_AddTraceback(const char *funcname, int c_line,
                               int py_line, const char *filename) {
    PyCodeObject *py_code = 0;
    PyFrameObject *py_frame = 0;
    PyThreadState *tstate = __Pyx_PyThreadState_Current;
    if (c_line) {
        c_line = __Pyx_CLineForTraceback(tstate, c_line);
    }
    py_code = __pyx_find_code_object(c_line ? -c_line : py_line);
    if (!py_code) {
        py_code = __Pyx_CreateCodeObjectForTraceback(
            funcname, c_line, py_line, filename);
        if (!py_code) goto bad;
        __pyx_insert_code_object(c_line ? -c_line : py_line, py_code);
    }
    py_frame = PyFrame_New(
        tstate,            /*PyThreadState *tstate,*/
        py_code,           /*PyCodeObject *code,*/
        __pyx_d,    /*PyObject *globals,*/
        0                  /*PyObject *locals*/
    );
    if (!py_frame) goto bad;
    __Pyx_PyFrame_SetLineNumber(py_frame, py_line);
    PyTraceBack_Here(py_frame);
bad:
    Py_XDECREF(py_code);
    Py_XDECREF(py_frame);
}

/* CIntToPy */
  static CYTHON_INLINE PyObject* __Pyx_PyInt_From_int(int value) {
    const int neg_one = (int) ((int) 0 - (int) 1), const_zero = (int) 0;
    const int is_unsigned = neg_one > const_zero;
    if (is_unsigned) {
        if (sizeof(int) < sizeof(long)) {
            return PyInt_FromLong((long) value);
        } else if (sizeof(int) <= sizeof(unsigned long)) {
            return PyLong_FromUnsignedLong((unsigned long) value);
#ifdef HAVE_LONG_LONG
        } else if (sizeof(int) <= sizeof(unsigned PY_LONG_LONG)) {
            return PyLong_FromUnsignedLongLong((unsigned PY_LONG_LONG) value);
#endif
        }
    } else {
        if (sizeof(int) <= sizeof(long)) {
            return PyInt_FromLong((long) value);
#ifdef HAVE_LONG_LONG
        } else if (sizeof(int) <= sizeof(PY_LONG_LONG)) {
            return PyLong_FromLongLong((PY_LONG_LONG) value);
#endif
        }
    }
    {
        int one = 1; int little = (int)*(unsigned char *)&one;
        unsigned char *bytes = (unsigned char *)&value;
        return _PyLong_FromByteArray(bytes, sizeof(int),
                                     little, !is_unsigned);
    }
}

/* CIntFromPyVerify */
  #define __PYX_VERIFY_RETURN_INT(target_type, func_type, func_value)\
    __PYX__VERIFY_RETURN_INT(target_type, func_type, func_value, 0)
#define __PYX_VERIFY_RETURN_INT_EXC(target_type, func_type, func_value)\
    __PYX__VERIFY_RETURN_INT(target_type, func_type, func_value, 1)
#define __PYX__VERIFY_RETURN_INT(target_type, func_type, func_value, exc)\
    {\
        func_type value = func_value;\
        if (sizeof(target_type) < sizeof(func_type)) {\
            if (unlikely(value != (func_type) (target_type) value)) {\
                func_type zero = 0;\
                if (exc && unlikely(value == (func_type)-1 && PyErr_Occurred()))\
                    return (target_type) -1;\
                if (is_unsigned && unlikely(value < zero))\
                    goto raise_neg_overflow;\
                else\
                    goto raise_overflow;\
            }\
        }\
        return (target_type) value;\
    }

/* ToPyCTupleUtility */
  static PyObject* __pyx_convert__to_py___pyx_ctuple_int__and_int(__pyx_ctuple_int__and_int value) {
    PyObject* item = NULL;
    PyObject* result = PyTuple_New(2);
    if (!result) goto bad;
        item = __Pyx_PyInt_From_int(value.f0);
        if (!item) goto bad;
        PyTuple_SET_ITEM(result, 0, item);
        item = __Pyx_PyInt_From_int(value.f1);
        if (!item) goto bad;
        PyTuple_SET_ITEM(result, 1, item);
    return result;
bad:
    Py_XDECREF(item);
    Py_XDECREF(result);
    return NULL;
}

/* FromPyCTupleUtility */
  static __pyx_ctuple_int__and_int __pyx_convert__from_py___pyx_ctuple_int__and_int(PyObject * o) {
    __pyx_ctuple_int__and_int result;
    if (!PyTuple_Check(o) || PyTuple_GET_SIZE(o) != 2) {
        PyErr_Format(PyExc_TypeError, "Expected %.16s of size %d, got %.200s", "a tuple", 2, Py_TYPE(o)->tp_name);
        goto bad;
    }
#if CYTHON_ASSUME_SAFE_MACROS && !CYTHON_AVOID_BORROWED_REFS
        result.f0 = __Pyx_PyInt_As_int(PyTuple_GET_ITEM(o, 0));
        if ((result.f0 == (int)-1) && PyErr_Occurred()) goto bad;
        result.f1 = __Pyx_PyInt_As_int(PyTuple_GET_ITEM(o, 1));
        if ((result.f1 == (int)-1) && PyErr_Occurred()) goto bad;
#else
    {
        PyObject *item;
        item = PySequence_ITEM(o, 0);  if (unlikely(!item)) goto bad;
        result.f0 = __Pyx_PyInt_As_int(item);
        Py_DECREF(item);
        if ((result.f0 == (int)-1) && PyErr_Occurred()) goto bad;
        item = PySequence_ITEM(o, 1);  if (unlikely(!item)) goto bad;
        result.f1 = __Pyx_PyInt_As_int(item);
        Py_DECREF(item);
        if ((result.f1 == (int)-1) && PyErr_Occurred()) goto bad;
    }
#endif
    return result;
bad:
    return result;
}

#if PY_MAJOR_VERSION < 3
static int __Pyx_GetBuffer(PyObject *obj, Py_buffer *view, int flags) {
    if (PyObject_CheckBuffer(obj)) return PyObject_GetBuffer(obj, view, flags);
        if (__Pyx_TypeCheck(obj, __pyx_ptype_7cpython_5array_array)) return __pyx_pw_7cpython_5array_5array_1__getbuffer__(obj, view, flags);
        if (__Pyx_TypeCheck(obj, __pyx_ptype_5numpy_ndarray)) return __pyx_pw_5numpy_7ndarray_1__getbuffer__(obj, view, flags);
        if (__Pyx_TypeCheck(obj, __pyx_array_type)) return __pyx_array_getbuffer(obj, view, flags);
        if (__Pyx_TypeCheck(obj, __pyx_memoryview_type)) return __pyx_memoryview_getbuffer(obj, view, flags);
    PyErr_Format(PyExc_TypeError, "'%.200s' does not have the buffer interface", Py_TYPE(obj)->tp_name);
    return -1;
}
static void __Pyx_ReleaseBuffer(Py_buffer *view) {
    PyObject *obj = view->obj;
    if (!obj) return;
    if (PyObject_CheckBuffer(obj)) {
        PyBuffer_Release(view);
        return;
    }
    if ((0)) {}
        else if (__Pyx_TypeCheck(obj, __pyx_ptype_7cpython_5array_array)) __pyx_pw_7cpython_5array_5array_3__releasebuffer__(obj, view);
        else if (__Pyx_TypeCheck(obj, __pyx_ptype_5numpy_ndarray)) __pyx_pw_5numpy_7ndarray_3__releasebuffer__(obj, view);
    view->obj = NULL;
    Py_DECREF(obj);
}
#endif


  /* MemviewSliceIsContig */
  static int
__pyx_memviewslice_is_contig(const __Pyx_memviewslice mvs, char order, int ndim)
{
    int i, index, step, start;
    Py_ssize_t itemsize = mvs.memview->view.itemsize;
    if (order == 'F') {
        step = 1;
        start = 0;
    } else {
        step = -1;
        start = ndim - 1;
    }
    for (i = 0; i < ndim; i++) {
        index = start + step * i;
        if (mvs.suboffsets[index] >= 0 || mvs.strides[index] != itemsize)
            return 0;
        itemsize *= mvs.shape[index];
    }
    return 1;
}

/* OverlappingSlices */
  static void
__pyx_get_array_memory_extents(__Pyx_memviewslice *slice,
                               void **out_start, void **out_end,
                               int ndim, size_t itemsize)
{
    char *start, *end;
    int i;
    start = end = slice->data;
    for (i = 0; i < ndim; i++) {
        Py_ssize_t stride = slice->strides[i];
        Py_ssize_t extent = slice->shape[i];
        if (extent == 0) {
            *out_start = *out_end = start;
            return;
        } else {
            if (stride > 0)
                end += stride * (extent - 1);
            else
                start += stride * (extent - 1);
        }
    }
    *out_start = start;
    *out_end = end + itemsize;
}
static int
__pyx_slices_overlap(__Pyx_memviewslice *slice1,
                     __Pyx_memviewslice *slice2,
                     int ndim, size_t itemsize)
{
    void *start1, *end1, *start2, *end2;
    __pyx_get_array_memory_extents(slice1, &start1, &end1, ndim, itemsize);
    __pyx_get_array_memory_extents(slice2, &start2, &end2, ndim, itemsize);
    return (start1 < end2) && (start2 < end1);
}

/* Capsule */
  static CYTHON_INLINE PyObject *
__pyx_capsule_create(void *p, CYTHON_UNUSED const char *sig)
{
    PyObject *cobj;
#if PY_VERSION_HEX >= 0x02070000
    cobj = PyCapsule_New(p, sig, NULL);
#else
    cobj = PyCObject_FromVoidPtr(p, NULL);
#endif
    return cobj;
}

/* CIntToPy */
  static CYTHON_INLINE PyObject* __Pyx_PyInt_From_char(char value) {
    const char neg_one = (char) ((char) 0 - (char) 1), const_zero = (char) 0;
    const int is_unsigned = neg_one > const_zero;
    if (is_unsigned) {
        if (sizeof(char) < sizeof(long)) {
            return PyInt_FromLong((long) value);
        } else if (sizeof(char) <= sizeof(unsigned long)) {
            return PyLong_FromUnsignedLong((unsigned long) value);
#ifdef HAVE_LONG_LONG
        } else if (sizeof(char) <= sizeof(unsigned PY_LONG_LONG)) {
            return PyLong_FromUnsignedLongLong((unsigned PY_LONG_LONG) value);
#endif
        }
    } else {
        if (sizeof(char) <= sizeof(long)) {
            return PyInt_FromLong((long) value);
#ifdef HAVE_LONG_LONG
        } else if (sizeof(char) <= sizeof(PY_LONG_LONG)) {
            return PyLong_FromLongLong((PY_LONG_LONG) value);
#endif
        }
    }
    {
        int one = 1; int little = (int)*(unsigned char *)&one;
        unsigned char *bytes = (unsigned char *)&value;
        return _PyLong_FromByteArray(bytes, sizeof(char),
                                     little, !is_unsigned);
    }
}

/* CIntToPy */
  static CYTHON_INLINE PyObject* __Pyx_PyInt_From_long(long value) {
    const long neg_one = (long) ((long) 0 - (long) 1), const_zero = (long) 0;
    const int is_unsigned = neg_one > const_zero;
    if (is_unsigned) {
        if (sizeof(long) < sizeof(long)) {
            return PyInt_FromLong((long) value);
        } else if (sizeof(long) <= sizeof(unsigned long)) {
            return PyLong_FromUnsignedLong((unsigned long) value);
#ifdef HAVE_LONG_LONG
        } else if (sizeof(long) <= sizeof(unsigned PY_LONG_LONG)) {
            return PyLong_FromUnsignedLongLong((unsigned PY_LONG_LONG) value);
#endif
        }
    } else {
        if (sizeof(long) <= sizeof(long)) {
            return PyInt_FromLong((long) value);
#ifdef HAVE_LONG_LONG
        } else if (sizeof(long) <= sizeof(PY_LONG_LONG)) {
            return PyLong_FromLongLong((PY_LONG_LONG) value);
#endif
        }
    }
    {
        int one = 1; int little = (int)*(unsigned char *)&one;
        unsigned char *bytes = (unsigned char *)&value;
        return _PyLong_FromByteArray(bytes, sizeof(long),
                                     little, !is_unsigned);
    }
}

/* FromPyCTupleUtility */
  static __pyx_ctuple_float__and_int__and_int__and_int __pyx_convert__from_py___pyx_ctuple_float__and_int__and_int__and_int(PyObject * o) {
    __pyx_ctuple_float__and_int__and_int__and_int result;
    if (!PyTuple_Check(o) || PyTuple_GET_SIZE(o) != 4) {
        PyErr_Format(PyExc_TypeError, "Expected %.16s of size %d, got %.200s", "a tuple", 4, Py_TYPE(o)->tp_name);
        goto bad;
    }
#if CYTHON_ASSUME_SAFE_MACROS && !CYTHON_AVOID_BORROWED_REFS
        result.f0 = __pyx_PyFloat_AsFloat(PyTuple_GET_ITEM(o, 0));
        if ((result.f0 == (float)-1) && PyErr_Occurred()) goto bad;
        result.f1 = __Pyx_PyInt_As_int(PyTuple_GET_ITEM(o, 1));
        if ((result.f1 == (int)-1) && PyErr_Occurred()) goto bad;
        result.f2 = __Pyx_PyInt_As_int(PyTuple_GET_ITEM(o, 2));
        if ((result.f2 == (int)-1) && PyErr_Occurred()) goto bad;
        result.f3 = __Pyx_PyInt_As_int(PyTuple_GET_ITEM(o, 3));
        if ((result.f3 == (int)-1) && PyErr_Occurred()) goto bad;
#else
    {
        PyObject *item;
        item = PySequence_ITEM(o, 0);  if (unlikely(!item)) goto bad;
        result.f0 = __pyx_PyFloat_AsFloat(item);
        Py_DECREF(item);
        if ((result.f0 == (float)-1) && PyErr_Occurred()) goto bad;
        item = PySequence_ITEM(o, 1);  if (unlikely(!item)) goto bad;
        result.f1 = __Pyx_PyInt_As_int(item);
        Py_DECREF(item);
        if ((result.f1 == (int)-1) && PyErr_Occurred()) goto bad;
        item = PySequence_ITEM(o, 2);  if (unlikely(!item)) goto bad;
        result.f2 = __Pyx_PyInt_As_int(item);
        Py_DECREF(item);
        if ((result.f2 == (int)-1) && PyErr_Occurred()) goto bad;
        item = PySequence_ITEM(o, 3);  if (unlikely(!item)) goto bad;
        result.f3 = __Pyx_PyInt_As_int(item);
        Py_DECREF(item);
        if ((result.f3 == (int)-1) && PyErr_Occurred()) goto bad;
    }
#endif
    return result;
bad:
    return result;
}

/* Declarations */
  #if CYTHON_CCOMPLEX
  #ifdef __cplusplus
    static CYTHON_INLINE __pyx_t_float_complex __pyx_t_float_complex_from_parts(float x, float y) {
      return ::std::complex< float >(x, y);
    }
  #else
    static CYTHON_INLINE __pyx_t_float_complex __pyx_t_float_complex_from_parts(float x, float y) {
      return x + y*(__pyx_t_float_complex)_Complex_I;
    }
  #endif
#else
    static CYTHON_INLINE __pyx_t_float_complex __pyx_t_float_complex_from_parts(float x, float y) {
      __pyx_t_float_complex z;
      z.real = x;
      z.imag = y;
      return z;
    }
#endif

/* Arithmetic */
  #if CYTHON_CCOMPLEX
#else
    static CYTHON_INLINE int __Pyx_c_eq_float(__pyx_t_float_complex a, __pyx_t_float_complex b) {
       return (a.real == b.real) && (a.imag == b.imag);
    }
    static CYTHON_INLINE __pyx_t_float_complex __Pyx_c_sum_float(__pyx_t_float_complex a, __pyx_t_float_complex b) {
        __pyx_t_float_complex z;
        z.real = a.real + b.real;
        z.imag = a.imag + b.imag;
        return z;
    }
    static CYTHON_INLINE __pyx_t_float_complex __Pyx_c_diff_float(__pyx_t_float_complex a, __pyx_t_float_complex b) {
        __pyx_t_float_complex z;
        z.real = a.real - b.real;
        z.imag = a.imag - b.imag;
        return z;
    }
    static CYTHON_INLINE __pyx_t_float_complex __Pyx_c_prod_float(__pyx_t_float_complex a, __pyx_t_float_complex b) {
        __pyx_t_float_complex z;
        z.real = a.real * b.real - a.imag * b.imag;
        z.imag = a.real * b.imag + a.imag * b.real;
        return z;
    }
    #if 1
    static CYTHON_INLINE __pyx_t_float_complex __Pyx_c_quot_float(__pyx_t_float_complex a, __pyx_t_float_complex b) {
        if (b.imag == 0) {
            return __pyx_t_float_complex_from_parts(a.real / b.real, a.imag / b.real);
        } else if (fabsf(b.real) >= fabsf(b.imag)) {
            if (b.real == 0 && b.imag == 0) {
                return __pyx_t_float_complex_from_parts(a.real / b.real, a.imag / b.imag);
            } else {
                float r = b.imag / b.real;
                float s = (float)(1.0) / (b.real + b.imag * r);
                return __pyx_t_float_complex_from_parts(
                    (a.real + a.imag * r) * s, (a.imag - a.real * r) * s);
            }
        } else {
            float r = b.real / b.imag;
            float s = (float)(1.0) / (b.imag + b.real * r);
            return __pyx_t_float_complex_from_parts(
                (a.real * r + a.imag) * s, (a.imag * r - a.real) * s);
        }
    }
    #else
    static CYTHON_INLINE __pyx_t_float_complex __Pyx_c_quot_float(__pyx_t_float_complex a, __pyx_t_float_complex b) {
        if (b.imag == 0) {
            return __pyx_t_float_complex_from_parts(a.real / b.real, a.imag / b.real);
        } else {
            float denom = b.real * b.real + b.imag * b.imag;
            return __pyx_t_float_complex_from_parts(
                (a.real * b.real + a.imag * b.imag) / denom,
                (a.imag * b.real - a.real * b.imag) / denom);
        }
    }
    #endif
    static CYTHON_INLINE __pyx_t_float_complex __Pyx_c_neg_float(__pyx_t_float_complex a) {
        __pyx_t_float_complex z;
        z.real = -a.real;
        z.imag = -a.imag;
        return z;
    }
    static CYTHON_INLINE int __Pyx_c_is_zero_float(__pyx_t_float_complex a) {
       return (a.real == 0) && (a.imag == 0);
    }
    static CYTHON_INLINE __pyx_t_float_complex __Pyx_c_conj_float(__pyx_t_float_complex a) {
        __pyx_t_float_complex z;
        z.real =  a.real;
        z.imag = -a.imag;
        return z;
    }
    #if 1
        static CYTHON_INLINE float __Pyx_c_abs_float(__pyx_t_float_complex z) {
          #if !defined(HAVE_HYPOT) || defined(_MSC_VER)
            return sqrtf(z.real*z.real + z.imag*z.imag);
          #else
            return hypotf(z.real, z.imag);
          #endif
        }
        static CYTHON_INLINE __pyx_t_float_complex __Pyx_c_pow_float(__pyx_t_float_complex a, __pyx_t_float_complex b) {
            __pyx_t_float_complex z;
            float r, lnr, theta, z_r, z_theta;
            if (b.imag == 0 && b.real == (int)b.real) {
                if (b.real < 0) {
                    float denom = a.real * a.real + a.imag * a.imag;
                    a.real = a.real / denom;
                    a.imag = -a.imag / denom;
                    b.real = -b.real;
                }
                switch ((int)b.real) {
                    case 0:
                        z.real = 1;
                        z.imag = 0;
                        return z;
                    case 1:
                        return a;
                    case 2:
                        z = __Pyx_c_prod_float(a, a);
                        return __Pyx_c_prod_float(a, a);
                    case 3:
                        z = __Pyx_c_prod_float(a, a);
                        return __Pyx_c_prod_float(z, a);
                    case 4:
                        z = __Pyx_c_prod_float(a, a);
                        return __Pyx_c_prod_float(z, z);
                }
            }
            if (a.imag == 0) {
                if (a.real == 0) {
                    return a;
                } else if (b.imag == 0) {
                    z.real = powf(a.real, b.real);
                    z.imag = 0;
                    return z;
                } else if (a.real > 0) {
                    r = a.real;
                    theta = 0;
                } else {
                    r = -a.real;
                    theta = atan2f(0.0, -1.0);
                }
            } else {
                r = __Pyx_c_abs_float(a);
                theta = atan2f(a.imag, a.real);
            }
            lnr = logf(r);
            z_r = expf(lnr * b.real - theta * b.imag);
            z_theta = theta * b.real + lnr * b.imag;
            z.real = z_r * cosf(z_theta);
            z.imag = z_r * sinf(z_theta);
            return z;
        }
    #endif
#endif

/* Declarations */
  #if CYTHON_CCOMPLEX
  #ifdef __cplusplus
    static CYTHON_INLINE __pyx_t_double_complex __pyx_t_double_complex_from_parts(double x, double y) {
      return ::std::complex< double >(x, y);
    }
  #else
    static CYTHON_INLINE __pyx_t_double_complex __pyx_t_double_complex_from_parts(double x, double y) {
      return x + y*(__pyx_t_double_complex)_Complex_I;
    }
  #endif
#else
    static CYTHON_INLINE __pyx_t_double_complex __pyx_t_double_complex_from_parts(double x, double y) {
      __pyx_t_double_complex z;
      z.real = x;
      z.imag = y;
      return z;
    }
#endif

/* Arithmetic */
  #if CYTHON_CCOMPLEX
#else
    static CYTHON_INLINE int __Pyx_c_eq_double(__pyx_t_double_complex a, __pyx_t_double_complex b) {
       return (a.real == b.real) && (a.imag == b.imag);
    }
    static CYTHON_INLINE __pyx_t_double_complex __Pyx_c_sum_double(__pyx_t_double_complex a, __pyx_t_double_complex b) {
        __pyx_t_double_complex z;
        z.real = a.real + b.real;
        z.imag = a.imag + b.imag;
        return z;
    }
    static CYTHON_INLINE __pyx_t_double_complex __Pyx_c_diff_double(__pyx_t_double_complex a, __pyx_t_double_complex b) {
        __pyx_t_double_complex z;
        z.real = a.real - b.real;
        z.imag = a.imag - b.imag;
        return z;
    }
    static CYTHON_INLINE __pyx_t_double_complex __Pyx_c_prod_double(__pyx_t_double_complex a, __pyx_t_double_complex b) {
        __pyx_t_double_complex z;
        z.real = a.real * b.real - a.imag * b.imag;
        z.imag = a.real * b.imag + a.imag * b.real;
        return z;
    }
    #if 1
    static CYTHON_INLINE __pyx_t_double_complex __Pyx_c_quot_double(__pyx_t_double_complex a, __pyx_t_double_complex b) {
        if (b.imag == 0) {
            return __pyx_t_double_complex_from_parts(a.real / b.real, a.imag / b.real);
        } else if (fabs(b.real) >= fabs(b.imag)) {
            if (b.real == 0 && b.imag == 0) {
                return __pyx_t_double_complex_from_parts(a.real / b.real, a.imag / b.imag);
            } else {
                double r = b.imag / b.real;
                double s = (double)(1.0) / (b.real + b.imag * r);
                return __pyx_t_double_complex_from_parts(
                    (a.real + a.imag * r) * s, (a.imag - a.real * r) * s);
            }
        } else {
            double r = b.real / b.imag;
            double s = (double)(1.0) / (b.imag + b.real * r);
            return __pyx_t_double_complex_from_parts(
                (a.real * r + a.imag) * s, (a.imag * r - a.real) * s);
        }
    }
    #else
    static CYTHON_INLINE __pyx_t_double_complex __Pyx_c_quot_double(__pyx_t_double_complex a, __pyx_t_double_complex b) {
        if (b.imag == 0) {
            return __pyx_t_double_complex_from_parts(a.real / b.real, a.imag / b.real);
        } else {
            double denom = b.real * b.real + b.imag * b.imag;
            return __pyx_t_double_complex_from_parts(
                (a.real * b.real + a.imag * b.imag) / denom,
                (a.imag * b.real - a.real * b.imag) / denom);
        }
    }
    #endif
    static CYTHON_INLINE __pyx_t_double_complex __Pyx_c_neg_double(__pyx_t_double_complex a) {
        __pyx_t_double_complex z;
        z.real = -a.real;
        z.imag = -a.imag;
        return z;
    }
    static CYTHON_INLINE int __Pyx_c_is_zero_double(__pyx_t_double_complex a) {
       return (a.real == 0) && (a.imag == 0);
    }
    static CYTHON_INLINE __pyx_t_double_complex __Pyx_c_conj_double(__pyx_t_double_complex a) {
        __pyx_t_double_complex z;
        z.real =  a.real;
        z.imag = -a.imag;
        return z;
    }
    #if 1
        static CYTHON_INLINE double __Pyx_c_abs_double(__pyx_t_double_complex z) {
          #if !defined(HAVE_HYPOT) || defined(_MSC_VER)
            return sqrt(z.real*z.real + z.imag*z.imag);
          #else
            return hypot(z.real, z.imag);
          #endif
        }
        static CYTHON_INLINE __pyx_t_double_complex __Pyx_c_pow_double(__pyx_t_double_complex a, __pyx_t_double_complex b) {
            __pyx_t_double_complex z;
            double r, lnr, theta, z_r, z_theta;
            if (b.imag == 0 && b.real == (int)b.real) {
                if (b.real < 0) {
                    double denom = a.real * a.real + a.imag * a.imag;
                    a.real = a.real / denom;
                    a.imag = -a.imag / denom;
                    b.real = -b.real;
                }
                switch ((int)b.real) {
                    case 0:
                        z.real = 1;
                        z.imag = 0;
                        return z;
                    case 1:
                        return a;
                    case 2:
                        z = __Pyx_c_prod_double(a, a);
                        return __Pyx_c_prod_double(a, a);
                    case 3:
                        z = __Pyx_c_prod_double(a, a);
                        return __Pyx_c_prod_double(z, a);
                    case 4:
                        z = __Pyx_c_prod_double(a, a);
                        return __Pyx_c_prod_double(z, z);
                }
            }
            if (a.imag == 0) {
                if (a.real == 0) {
                    return a;
                } else if (b.imag == 0) {
                    z.real = pow(a.real, b.real);
                    z.imag = 0;
                    return z;
                } else if (a.real > 0) {
                    r = a.real;
                    theta = 0;
                } else {
                    r = -a.real;
                    theta = atan2(0.0, -1.0);
                }
            } else {
                r = __Pyx_c_abs_double(a);
                theta = atan2(a.imag, a.real);
            }
            lnr = log(r);
            z_r = exp(lnr * b.real - theta * b.imag);
            z_theta = theta * b.real + lnr * b.imag;
            z.real = z_r * cos(z_theta);
            z.imag = z_r * sin(z_theta);
            return z;
        }
    #endif
#endif

/* CIntToPy */
  static CYTHON_INLINE PyObject* __Pyx_PyInt_From_enum__NPY_TYPES(enum NPY_TYPES value) {
    const enum NPY_TYPES neg_one = (enum NPY_TYPES) ((enum NPY_TYPES) 0 - (enum NPY_TYPES) 1), const_zero = (enum NPY_TYPES) 0;
    const int is_unsigned = neg_one > const_zero;
    if (is_unsigned) {
        if (sizeof(enum NPY_TYPES) < sizeof(long)) {
            return PyInt_FromLong((long) value);
        } else if (sizeof(enum NPY_TYPES) <= sizeof(unsigned long)) {
            return PyLong_FromUnsignedLong((unsigned long) value);
#ifdef HAVE_LONG_LONG
        } else if (sizeof(enum NPY_TYPES) <= sizeof(unsigned PY_LONG_LONG)) {
            return PyLong_FromUnsignedLongLong((unsigned PY_LONG_LONG) value);
#endif
        }
    } else {
        if (sizeof(enum NPY_TYPES) <= sizeof(long)) {
            return PyInt_FromLong((long) value);
#ifdef HAVE_LONG_LONG
        } else if (sizeof(enum NPY_TYPES) <= sizeof(PY_LONG_LONG)) {
            return PyLong_FromLongLong((PY_LONG_LONG) value);
#endif
        }
    }
    {
        int one = 1; int little = (int)*(unsigned char *)&one;
        unsigned char *bytes = (unsigned char *)&value;
        return _PyLong_FromByteArray(bytes, sizeof(enum NPY_TYPES),
                                     little, !is_unsigned);
    }
}

/* CIntFromPy */
  static CYTHON_INLINE int __Pyx_PyInt_As_int(PyObject *x) {
    const int neg_one = (int) ((int) 0 - (int) 1), const_zero = (int) 0;
    const int is_unsigned = neg_one > const_zero;
#if PY_MAJOR_VERSION < 3
    if (likely(PyInt_Check(x))) {
        if (sizeof(int) < sizeof(long)) {
            __PYX_VERIFY_RETURN_INT(int, long, PyInt_AS_LONG(x))
        } else {
            long val = PyInt_AS_LONG(x);
            if (is_unsigned && unlikely(val < 0)) {
                goto raise_neg_overflow;
            }
            return (int) val;
        }
    } else
#endif
    if (likely(PyLong_Check(x))) {
        if (is_unsigned) {
#if CYTHON_USE_PYLONG_INTERNALS
            const digit* digits = ((PyLongObject*)x)->ob_digit;
            switch (Py_SIZE(x)) {
                case  0: return (int) 0;
                case  1: __PYX_VERIFY_RETURN_INT(int, digit, digits[0])
                case 2:
                    if (8 * sizeof(int) > 1 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 2 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(int, unsigned long, (((((unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(int) >= 2 * PyLong_SHIFT) {
                            return (int) (((((int)digits[1]) << PyLong_SHIFT) | (int)digits[0]));
                        }
                    }
                    break;
                case 3:
                    if (8 * sizeof(int) > 2 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 3 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(int, unsigned long, (((((((unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(int) >= 3 * PyLong_SHIFT) {
                            return (int) (((((((int)digits[2]) << PyLong_SHIFT) | (int)digits[1]) << PyLong_SHIFT) | (int)digits[0]));
                        }
                    }
                    break;
                case 4:
                    if (8 * sizeof(int) > 3 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 4 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(int, unsigned long, (((((((((unsigned long)digits[3]) << PyLong_SHIFT) | (unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(int) >= 4 * PyLong_SHIFT) {
                            return (int) (((((((((int)digits[3]) << PyLong_SHIFT) | (int)digits[2]) << PyLong_SHIFT) | (int)digits[1]) << PyLong_SHIFT) | (int)digits[0]));
                        }
                    }
                    break;
            }
#endif
#if CYTHON_COMPILING_IN_CPYTHON
            if (unlikely(Py_SIZE(x) < 0)) {
                goto raise_neg_overflow;
            }
#else
            {
                int result = PyObject_RichCompareBool(x, Py_False, Py_LT);
                if (unlikely(result < 0))
                    return (int) -1;
                if (unlikely(result == 1))
                    goto raise_neg_overflow;
            }
#endif
            if (sizeof(int) <= sizeof(unsigned long)) {
                __PYX_VERIFY_RETURN_INT_EXC(int, unsigned long, PyLong_AsUnsignedLong(x))
#ifdef HAVE_LONG_LONG
            } else if (sizeof(int) <= sizeof(unsigned PY_LONG_LONG)) {
                __PYX_VERIFY_RETURN_INT_EXC(int, unsigned PY_LONG_LONG, PyLong_AsUnsignedLongLong(x))
#endif
            }
        } else {
#if CYTHON_USE_PYLONG_INTERNALS
            const digit* digits = ((PyLongObject*)x)->ob_digit;
            switch (Py_SIZE(x)) {
                case  0: return (int) 0;
                case -1: __PYX_VERIFY_RETURN_INT(int, sdigit, (sdigit) (-(sdigit)digits[0]))
                case  1: __PYX_VERIFY_RETURN_INT(int,  digit, +digits[0])
                case -2:
                    if (8 * sizeof(int) - 1 > 1 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 2 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(int, long, -(long) (((((unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(int) - 1 > 2 * PyLong_SHIFT) {
                            return (int) (((int)-1)*(((((int)digits[1]) << PyLong_SHIFT) | (int)digits[0])));
                        }
                    }
                    break;
                case 2:
                    if (8 * sizeof(int) > 1 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 2 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(int, unsigned long, (((((unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(int) - 1 > 2 * PyLong_SHIFT) {
                            return (int) ((((((int)digits[1]) << PyLong_SHIFT) | (int)digits[0])));
                        }
                    }
                    break;
                case -3:
                    if (8 * sizeof(int) - 1 > 2 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 3 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(int, long, -(long) (((((((unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(int) - 1 > 3 * PyLong_SHIFT) {
                            return (int) (((int)-1)*(((((((int)digits[2]) << PyLong_SHIFT) | (int)digits[1]) << PyLong_SHIFT) | (int)digits[0])));
                        }
                    }
                    break;
                case 3:
                    if (8 * sizeof(int) > 2 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 3 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(int, unsigned long, (((((((unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(int) - 1 > 3 * PyLong_SHIFT) {
                            return (int) ((((((((int)digits[2]) << PyLong_SHIFT) | (int)digits[1]) << PyLong_SHIFT) | (int)digits[0])));
                        }
                    }
                    break;
                case -4:
                    if (8 * sizeof(int) - 1 > 3 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 4 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(int, long, -(long) (((((((((unsigned long)digits[3]) << PyLong_SHIFT) | (unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(int) - 1 > 4 * PyLong_SHIFT) {
                            return (int) (((int)-1)*(((((((((int)digits[3]) << PyLong_SHIFT) | (int)digits[2]) << PyLong_SHIFT) | (int)digits[1]) << PyLong_SHIFT) | (int)digits[0])));
                        }
                    }
                    break;
                case 4:
                    if (8 * sizeof(int) > 3 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 4 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(int, unsigned long, (((((((((unsigned long)digits[3]) << PyLong_SHIFT) | (unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(int) - 1 > 4 * PyLong_SHIFT) {
                            return (int) ((((((((((int)digits[3]) << PyLong_SHIFT) | (int)digits[2]) << PyLong_SHIFT) | (int)digits[1]) << PyLong_SHIFT) | (int)digits[0])));
                        }
                    }
                    break;
            }
#endif
            if (sizeof(int) <= sizeof(long)) {
                __PYX_VERIFY_RETURN_INT_EXC(int, long, PyLong_AsLong(x))
#ifdef HAVE_LONG_LONG
            } else if (sizeof(int) <= sizeof(PY_LONG_LONG)) {
                __PYX_VERIFY_RETURN_INT_EXC(int, PY_LONG_LONG, PyLong_AsLongLong(x))
#endif
            }
        }
        {
#if CYTHON_COMPILING_IN_PYPY && !defined(_PyLong_AsByteArray)
            PyErr_SetString(PyExc_RuntimeError,
                            "_PyLong_AsByteArray() not available in PyPy, cannot convert large numbers");
#else
            int val;
            PyObject *v = __Pyx_PyNumber_IntOrLong(x);
 #if PY_MAJOR_VERSION < 3
            if (likely(v) && !PyLong_Check(v)) {
                PyObject *tmp = v;
                v = PyNumber_Long(tmp);
                Py_DECREF(tmp);
            }
 #endif
            if (likely(v)) {
                int one = 1; int is_little = (int)*(unsigned char *)&one;
                unsigned char *bytes = (unsigned char *)&val;
                int ret = _PyLong_AsByteArray((PyLongObject *)v,
                                              bytes, sizeof(val),
                                              is_little, !is_unsigned);
                Py_DECREF(v);
                if (likely(!ret))
                    return val;
            }
#endif
            return (int) -1;
        }
    } else {
        int val;
        PyObject *tmp = __Pyx_PyNumber_IntOrLong(x);
        if (!tmp) return (int) -1;
        val = __Pyx_PyInt_As_int(tmp);
        Py_DECREF(tmp);
        return val;
    }
raise_overflow:
    PyErr_SetString(PyExc_OverflowError,
        "value too large to convert to int");
    return (int) -1;
raise_neg_overflow:
    PyErr_SetString(PyExc_OverflowError,
        "can't convert negative value to int");
    return (int) -1;
}

/* MemviewSliceCopyTemplate */
  static __Pyx_memviewslice
__pyx_memoryview_copy_new_contig(const __Pyx_memviewslice *from_mvs,
                                 const char *mode, int ndim,
                                 size_t sizeof_dtype, int contig_flag,
                                 int dtype_is_object)
{
    __Pyx_RefNannyDeclarations
    int i;
    __Pyx_memviewslice new_mvs = { 0, 0, { 0 }, { 0 }, { 0 } };
    struct __pyx_memoryview_obj *from_memview = from_mvs->memview;
    Py_buffer *buf = &from_memview->view;
    PyObject *shape_tuple = NULL;
    PyObject *temp_int = NULL;
    struct __pyx_array_obj *array_obj = NULL;
    struct __pyx_memoryview_obj *memview_obj = NULL;
    __Pyx_RefNannySetupContext("__pyx_memoryview_copy_new_contig", 0);
    for (i = 0; i < ndim; i++) {
        if (from_mvs->suboffsets[i] >= 0) {
            PyErr_Format(PyExc_ValueError, "Cannot copy memoryview slice with "
                                           "indirect dimensions (axis %d)", i);
            goto fail;
        }
    }
    shape_tuple = PyTuple_New(ndim);
    if (unlikely(!shape_tuple)) {
        goto fail;
    }
    __Pyx_GOTREF(shape_tuple);
    for(i = 0; i < ndim; i++) {
        temp_int = PyInt_FromSsize_t(from_mvs->shape[i]);
        if(unlikely(!temp_int)) {
            goto fail;
        } else {
            PyTuple_SET_ITEM(shape_tuple, i, temp_int);
            temp_int = NULL;
        }
    }
    array_obj = __pyx_array_new(shape_tuple, sizeof_dtype, buf->format, (char *) mode, NULL);
    if (unlikely(!array_obj)) {
        goto fail;
    }
    __Pyx_GOTREF(array_obj);
    memview_obj = (struct __pyx_memoryview_obj *) __pyx_memoryview_new(
                                    (PyObject *) array_obj, contig_flag,
                                    dtype_is_object,
                                    from_mvs->memview->typeinfo);
    if (unlikely(!memview_obj))
        goto fail;
    if (unlikely(__Pyx_init_memviewslice(memview_obj, ndim, &new_mvs, 1) < 0))
        goto fail;
    if (unlikely(__pyx_memoryview_copy_contents(*from_mvs, new_mvs, ndim, ndim,
                                                dtype_is_object) < 0))
        goto fail;
    goto no_fail;
fail:
    __Pyx_XDECREF(new_mvs.memview);
    new_mvs.memview = NULL;
    new_mvs.data = NULL;
no_fail:
    __Pyx_XDECREF(shape_tuple);
    __Pyx_XDECREF(temp_int);
    __Pyx_XDECREF(array_obj);
    __Pyx_RefNannyFinishContext();
    return new_mvs;
}

/* CIntFromPy */
  static CYTHON_INLINE char __Pyx_PyInt_As_char(PyObject *x) {
    const char neg_one = (char) ((char) 0 - (char) 1), const_zero = (char) 0;
    const int is_unsigned = neg_one > const_zero;
#if PY_MAJOR_VERSION < 3
    if (likely(PyInt_Check(x))) {
        if (sizeof(char) < sizeof(long)) {
            __PYX_VERIFY_RETURN_INT(char, long, PyInt_AS_LONG(x))
        } else {
            long val = PyInt_AS_LONG(x);
            if (is_unsigned && unlikely(val < 0)) {
                goto raise_neg_overflow;
            }
            return (char) val;
        }
    } else
#endif
    if (likely(PyLong_Check(x))) {
        if (is_unsigned) {
#if CYTHON_USE_PYLONG_INTERNALS
            const digit* digits = ((PyLongObject*)x)->ob_digit;
            switch (Py_SIZE(x)) {
                case  0: return (char) 0;
                case  1: __PYX_VERIFY_RETURN_INT(char, digit, digits[0])
                case 2:
                    if (8 * sizeof(char) > 1 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 2 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(char, unsigned long, (((((unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(char) >= 2 * PyLong_SHIFT) {
                            return (char) (((((char)digits[1]) << PyLong_SHIFT) | (char)digits[0]));
                        }
                    }
                    break;
                case 3:
                    if (8 * sizeof(char) > 2 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 3 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(char, unsigned long, (((((((unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(char) >= 3 * PyLong_SHIFT) {
                            return (char) (((((((char)digits[2]) << PyLong_SHIFT) | (char)digits[1]) << PyLong_SHIFT) | (char)digits[0]));
                        }
                    }
                    break;
                case 4:
                    if (8 * sizeof(char) > 3 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 4 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(char, unsigned long, (((((((((unsigned long)digits[3]) << PyLong_SHIFT) | (unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(char) >= 4 * PyLong_SHIFT) {
                            return (char) (((((((((char)digits[3]) << PyLong_SHIFT) | (char)digits[2]) << PyLong_SHIFT) | (char)digits[1]) << PyLong_SHIFT) | (char)digits[0]));
                        }
                    }
                    break;
            }
#endif
#if CYTHON_COMPILING_IN_CPYTHON
            if (unlikely(Py_SIZE(x) < 0)) {
                goto raise_neg_overflow;
            }
#else
            {
                int result = PyObject_RichCompareBool(x, Py_False, Py_LT);
                if (unlikely(result < 0))
                    return (char) -1;
                if (unlikely(result == 1))
                    goto raise_neg_overflow;
            }
#endif
            if (sizeof(char) <= sizeof(unsigned long)) {
                __PYX_VERIFY_RETURN_INT_EXC(char, unsigned long, PyLong_AsUnsignedLong(x))
#ifdef HAVE_LONG_LONG
            } else if (sizeof(char) <= sizeof(unsigned PY_LONG_LONG)) {
                __PYX_VERIFY_RETURN_INT_EXC(char, unsigned PY_LONG_LONG, PyLong_AsUnsignedLongLong(x))
#endif
            }
        } else {
#if CYTHON_USE_PYLONG_INTERNALS
            const digit* digits = ((PyLongObject*)x)->ob_digit;
            switch (Py_SIZE(x)) {
                case  0: return (char) 0;
                case -1: __PYX_VERIFY_RETURN_INT(char, sdigit, (sdigit) (-(sdigit)digits[0]))
                case  1: __PYX_VERIFY_RETURN_INT(char,  digit, +digits[0])
                case -2:
                    if (8 * sizeof(char) - 1 > 1 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 2 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(char, long, -(long) (((((unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(char) - 1 > 2 * PyLong_SHIFT) {
                            return (char) (((char)-1)*(((((char)digits[1]) << PyLong_SHIFT) | (char)digits[0])));
                        }
                    }
                    break;
                case 2:
                    if (8 * sizeof(char) > 1 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 2 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(char, unsigned long, (((((unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(char) - 1 > 2 * PyLong_SHIFT) {
                            return (char) ((((((char)digits[1]) << PyLong_SHIFT) | (char)digits[0])));
                        }
                    }
                    break;
                case -3:
                    if (8 * sizeof(char) - 1 > 2 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 3 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(char, long, -(long) (((((((unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(char) - 1 > 3 * PyLong_SHIFT) {
                            return (char) (((char)-1)*(((((((char)digits[2]) << PyLong_SHIFT) | (char)digits[1]) << PyLong_SHIFT) | (char)digits[0])));
                        }
                    }
                    break;
                case 3:
                    if (8 * sizeof(char) > 2 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 3 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(char, unsigned long, (((((((unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(char) - 1 > 3 * PyLong_SHIFT) {
                            return (char) ((((((((char)digits[2]) << PyLong_SHIFT) | (char)digits[1]) << PyLong_SHIFT) | (char)digits[0])));
                        }
                    }
                    break;
                case -4:
                    if (8 * sizeof(char) - 1 > 3 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 4 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(char, long, -(long) (((((((((unsigned long)digits[3]) << PyLong_SHIFT) | (unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(char) - 1 > 4 * PyLong_SHIFT) {
                            return (char) (((char)-1)*(((((((((char)digits[3]) << PyLong_SHIFT) | (char)digits[2]) << PyLong_SHIFT) | (char)digits[1]) << PyLong_SHIFT) | (char)digits[0])));
                        }
                    }
                    break;
                case 4:
                    if (8 * sizeof(char) > 3 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 4 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(char, unsigned long, (((((((((unsigned long)digits[3]) << PyLong_SHIFT) | (unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(char) - 1 > 4 * PyLong_SHIFT) {
                            return (char) ((((((((((char)digits[3]) << PyLong_SHIFT) | (char)digits[2]) << PyLong_SHIFT) | (char)digits[1]) << PyLong_SHIFT) | (char)digits[0])));
                        }
                    }
                    break;
            }
#endif
            if (sizeof(char) <= sizeof(long)) {
                __PYX_VERIFY_RETURN_INT_EXC(char, long, PyLong_AsLong(x))
#ifdef HAVE_LONG_LONG
            } else if (sizeof(char) <= sizeof(PY_LONG_LONG)) {
                __PYX_VERIFY_RETURN_INT_EXC(char, PY_LONG_LONG, PyLong_AsLongLong(x))
#endif
            }
        }
        {
#if CYTHON_COMPILING_IN_PYPY && !defined(_PyLong_AsByteArray)
            PyErr_SetString(PyExc_RuntimeError,
                            "_PyLong_AsByteArray() not available in PyPy, cannot convert large numbers");
#else
            char val;
            PyObject *v = __Pyx_PyNumber_IntOrLong(x);
 #if PY_MAJOR_VERSION < 3
            if (likely(v) && !PyLong_Check(v)) {
                PyObject *tmp = v;
                v = PyNumber_Long(tmp);
                Py_DECREF(tmp);
            }
 #endif
            if (likely(v)) {
                int one = 1; int is_little = (int)*(unsigned char *)&one;
                unsigned char *bytes = (unsigned char *)&val;
                int ret = _PyLong_AsByteArray((PyLongObject *)v,
                                              bytes, sizeof(val),
                                              is_little, !is_unsigned);
                Py_DECREF(v);
                if (likely(!ret))
                    return val;
            }
#endif
            return (char) -1;
        }
    } else {
        char val;
        PyObject *tmp = __Pyx_PyNumber_IntOrLong(x);
        if (!tmp) return (char) -1;
        val = __Pyx_PyInt_As_char(tmp);
        Py_DECREF(tmp);
        return val;
    }
raise_overflow:
    PyErr_SetString(PyExc_OverflowError,
        "value too large to convert to char");
    return (char) -1;
raise_neg_overflow:
    PyErr_SetString(PyExc_OverflowError,
        "can't convert negative value to char");
    return (char) -1;
}

/* CIntFromPy */
  static CYTHON_INLINE long __Pyx_PyInt_As_long(PyObject *x) {
    const long neg_one = (long) ((long) 0 - (long) 1), const_zero = (long) 0;
    const int is_unsigned = neg_one > const_zero;
#if PY_MAJOR_VERSION < 3
    if (likely(PyInt_Check(x))) {
        if (sizeof(long) < sizeof(long)) {
            __PYX_VERIFY_RETURN_INT(long, long, PyInt_AS_LONG(x))
        } else {
            long val = PyInt_AS_LONG(x);
            if (is_unsigned && unlikely(val < 0)) {
                goto raise_neg_overflow;
            }
            return (long) val;
        }
    } else
#endif
    if (likely(PyLong_Check(x))) {
        if (is_unsigned) {
#if CYTHON_USE_PYLONG_INTERNALS
            const digit* digits = ((PyLongObject*)x)->ob_digit;
            switch (Py_SIZE(x)) {
                case  0: return (long) 0;
                case  1: __PYX_VERIFY_RETURN_INT(long, digit, digits[0])
                case 2:
                    if (8 * sizeof(long) > 1 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 2 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(long, unsigned long, (((((unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(long) >= 2 * PyLong_SHIFT) {
                            return (long) (((((long)digits[1]) << PyLong_SHIFT) | (long)digits[0]));
                        }
                    }
                    break;
                case 3:
                    if (8 * sizeof(long) > 2 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 3 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(long, unsigned long, (((((((unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(long) >= 3 * PyLong_SHIFT) {
                            return (long) (((((((long)digits[2]) << PyLong_SHIFT) | (long)digits[1]) << PyLong_SHIFT) | (long)digits[0]));
                        }
                    }
                    break;
                case 4:
                    if (8 * sizeof(long) > 3 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 4 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(long, unsigned long, (((((((((unsigned long)digits[3]) << PyLong_SHIFT) | (unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(long) >= 4 * PyLong_SHIFT) {
                            return (long) (((((((((long)digits[3]) << PyLong_SHIFT) | (long)digits[2]) << PyLong_SHIFT) | (long)digits[1]) << PyLong_SHIFT) | (long)digits[0]));
                        }
                    }
                    break;
            }
#endif
#if CYTHON_COMPILING_IN_CPYTHON
            if (unlikely(Py_SIZE(x) < 0)) {
                goto raise_neg_overflow;
            }
#else
            {
                int result = PyObject_RichCompareBool(x, Py_False, Py_LT);
                if (unlikely(result < 0))
                    return (long) -1;
                if (unlikely(result == 1))
                    goto raise_neg_overflow;
            }
#endif
            if (sizeof(long) <= sizeof(unsigned long)) {
                __PYX_VERIFY_RETURN_INT_EXC(long, unsigned long, PyLong_AsUnsignedLong(x))
#ifdef HAVE_LONG_LONG
            } else if (sizeof(long) <= sizeof(unsigned PY_LONG_LONG)) {
                __PYX_VERIFY_RETURN_INT_EXC(long, unsigned PY_LONG_LONG, PyLong_AsUnsignedLongLong(x))
#endif
            }
        } else {
#if CYTHON_USE_PYLONG_INTERNALS
            const digit* digits = ((PyLongObject*)x)->ob_digit;
            switch (Py_SIZE(x)) {
                case  0: return (long) 0;
                case -1: __PYX_VERIFY_RETURN_INT(long, sdigit, (sdigit) (-(sdigit)digits[0]))
                case  1: __PYX_VERIFY_RETURN_INT(long,  digit, +digits[0])
                case -2:
                    if (8 * sizeof(long) - 1 > 1 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 2 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(long, long, -(long) (((((unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(long) - 1 > 2 * PyLong_SHIFT) {
                            return (long) (((long)-1)*(((((long)digits[1]) << PyLong_SHIFT) | (long)digits[0])));
                        }
                    }
                    break;
                case 2:
                    if (8 * sizeof(long) > 1 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 2 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(long, unsigned long, (((((unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(long) - 1 > 2 * PyLong_SHIFT) {
                            return (long) ((((((long)digits[1]) << PyLong_SHIFT) | (long)digits[0])));
                        }
                    }
                    break;
                case -3:
                    if (8 * sizeof(long) - 1 > 2 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 3 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(long, long, -(long) (((((((unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(long) - 1 > 3 * PyLong_SHIFT) {
                            return (long) (((long)-1)*(((((((long)digits[2]) << PyLong_SHIFT) | (long)digits[1]) << PyLong_SHIFT) | (long)digits[0])));
                        }
                    }
                    break;
                case 3:
                    if (8 * sizeof(long) > 2 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 3 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(long, unsigned long, (((((((unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(long) - 1 > 3 * PyLong_SHIFT) {
                            return (long) ((((((((long)digits[2]) << PyLong_SHIFT) | (long)digits[1]) << PyLong_SHIFT) | (long)digits[0])));
                        }
                    }
                    break;
                case -4:
                    if (8 * sizeof(long) - 1 > 3 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 4 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(long, long, -(long) (((((((((unsigned long)digits[3]) << PyLong_SHIFT) | (unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(long) - 1 > 4 * PyLong_SHIFT) {
                            return (long) (((long)-1)*(((((((((long)digits[3]) << PyLong_SHIFT) | (long)digits[2]) << PyLong_SHIFT) | (long)digits[1]) << PyLong_SHIFT) | (long)digits[0])));
                        }
                    }
                    break;
                case 4:
                    if (8 * sizeof(long) > 3 * PyLong_SHIFT) {
                        if (8 * sizeof(unsigned long) > 4 * PyLong_SHIFT) {
                            __PYX_VERIFY_RETURN_INT(long, unsigned long, (((((((((unsigned long)digits[3]) << PyLong_SHIFT) | (unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                        } else if (8 * sizeof(long) - 1 > 4 * PyLong_SHIFT) {
                            return (long) ((((((((((long)digits[3]) << PyLong_SHIFT) | (long)digits[2]) << PyLong_SHIFT) | (long)digits[1]) << PyLong_SHIFT) | (long)digits[0])));
                        }
                    }
                    break;
            }
#endif
            if (sizeof(long) <= sizeof(long)) {
                __PYX_VERIFY_RETURN_INT_EXC(long, long, PyLong_AsLong(x))
#ifdef HAVE_LONG_LONG
            } else if (sizeof(long) <= sizeof(PY_LONG_LONG)) {
                __PYX_VERIFY_RETURN_INT_EXC(long, PY_LONG_LONG, PyLong_AsLongLong(x))
#endif
            }
        }
        {
#if CYTHON_COMPILING_IN_PYPY && !defined(_PyLong_AsByteArray)
            PyErr_SetString(PyExc_RuntimeError,
                            "_PyLong_AsByteArray() not available in PyPy, cannot convert large numbers");
#else
            long val;
            PyObject *v = __Pyx_PyNumber_IntOrLong(x);
 #if PY_MAJOR_VERSION < 3
            if (likely(v) && !PyLong_Check(v)) {
                PyObject *tmp = v;
                v = PyNumber_Long(tmp);
                Py_DECREF(tmp);
            }
 #endif
            if (likely(v)) {
                int one = 1; int is_little = (int)*(unsigned char *)&one;
                unsigned char *bytes = (unsigned char *)&val;
                int ret = _PyLong_AsByteArray((PyLongObject *)v,
                                              bytes, sizeof(val),
                                              is_little, !is_unsigned);
                Py_DECREF(v);
                if (likely(!ret))
                    return val;
            }
#endif
            return (long) -1;
        }
    } else {
        long val;
        PyObject *tmp = __Pyx_PyNumber_IntOrLong(x);
        if (!tmp) return (long) -1;
        val = __Pyx_PyInt_As_long(tmp);
        Py_DECREF(tmp);
        return val;
    }
raise_overflow:
    PyErr_SetString(PyExc_OverflowError,
        "value too large to convert to long");
    return (long) -1;
raise_neg_overflow:
    PyErr_SetString(PyExc_OverflowError,
        "can't convert negative value to long");
    return (long) -1;
}

/* FetchCommonType */
  static PyTypeObject* __Pyx_FetchCommonType(PyTypeObject* type) {
    PyObject* fake_module;
    PyTypeObject* cached_type = NULL;
    fake_module = PyImport_AddModule((char*) "_cython_" CYTHON_ABI);
    if (!fake_module) return NULL;
    Py_INCREF(fake_module);
    cached_type = (PyTypeObject*) PyObject_GetAttrString(fake_module, type->tp_name);
    if (cached_type) {
        if (!PyType_Check((PyObject*)cached_type)) {
            PyErr_Format(PyExc_TypeError,
                "Shared Cython type %.200s is not a type object",
                type->tp_name);
            goto bad;
        }
        if (cached_type->tp_basicsize != type->tp_basicsize) {
            PyErr_Format(PyExc_TypeError,
                "Shared Cython type %.200s has the wrong size, try recompiling",
                type->tp_name);
            goto bad;
        }
    } else {
        if (!PyErr_ExceptionMatches(PyExc_AttributeError)) goto bad;
        PyErr_Clear();
        if (PyType_Ready(type) < 0) goto bad;
        if (PyObject_SetAttrString(fake_module, type->tp_name, (PyObject*) type) < 0)
            goto bad;
        Py_INCREF(type);
        cached_type = type;
    }
done:
    Py_DECREF(fake_module);
    return cached_type;
bad:
    Py_XDECREF(cached_type);
    cached_type = NULL;
    goto done;
}

/* CoroutineBase */
  #include <structmember.h>
#include <frameobject.h>
#define __Pyx_Coroutine_Undelegate(gen) Py_CLEAR((gen)->yieldfrom)
static int __Pyx_PyGen__FetchStopIterationValue(CYTHON_UNUSED PyThreadState *__pyx_tstate, PyObject **pvalue) {
    PyObject *et, *ev, *tb;
    PyObject *value = NULL;
    __Pyx_ErrFetch(&et, &ev, &tb);
    if (!et) {
        Py_XDECREF(tb);
        Py_XDECREF(ev);
        Py_INCREF(Py_None);
        *pvalue = Py_None;
        return 0;
    }
    if (likely(et == PyExc_StopIteration)) {
        if (!ev) {
            Py_INCREF(Py_None);
            value = Py_None;
        }
#if PY_VERSION_HEX >= 0x030300A0
        else if (Py_TYPE(ev) == (PyTypeObject*)PyExc_StopIteration) {
            value = ((PyStopIterationObject *)ev)->value;
            Py_INCREF(value);
            Py_DECREF(ev);
        }
#endif
        else if (unlikely(PyTuple_Check(ev))) {
            if (PyTuple_GET_SIZE(ev) >= 1) {
#if CYTHON_ASSUME_SAFE_MACROS && !CYTHON_AVOID_BORROWED_REFS
                value = PyTuple_GET_ITEM(ev, 0);
                Py_INCREF(value);
#else
                value = PySequence_ITEM(ev, 0);
#endif
            } else {
                Py_INCREF(Py_None);
                value = Py_None;
            }
            Py_DECREF(ev);
        }
        else if (!__Pyx_TypeCheck(ev, (PyTypeObject*)PyExc_StopIteration)) {
            value = ev;
        }
        if (likely(value)) {
            Py_XDECREF(tb);
            Py_DECREF(et);
            *pvalue = value;
            return 0;
        }
    } else if (!__Pyx_PyErr_GivenExceptionMatches(et, PyExc_StopIteration)) {
        __Pyx_ErrRestore(et, ev, tb);
        return -1;
    }
    PyErr_NormalizeException(&et, &ev, &tb);
    if (unlikely(!PyObject_TypeCheck(ev, (PyTypeObject*)PyExc_StopIteration))) {
        __Pyx_ErrRestore(et, ev, tb);
        return -1;
    }
    Py_XDECREF(tb);
    Py_DECREF(et);
#if PY_VERSION_HEX >= 0x030300A0
    value = ((PyStopIterationObject *)ev)->value;
    Py_INCREF(value);
    Py_DECREF(ev);
#else
    {
        PyObject* args = __Pyx_PyObject_GetAttrStr(ev, __pyx_n_s_args);
        Py_DECREF(ev);
        if (likely(args)) {
            value = PySequence_GetItem(args, 0);
            Py_DECREF(args);
        }
        if (unlikely(!value)) {
            __Pyx_ErrRestore(NULL, NULL, NULL);
            Py_INCREF(Py_None);
            value = Py_None;
        }
    }
#endif
    *pvalue = value;
    return 0;
}
static CYTHON_INLINE
void __Pyx_Coroutine_ExceptionClear(__Pyx_ExcInfoStruct *exc_state) {
    PyObject *t, *v, *tb;
    t = exc_state->exc_type;
    v = exc_state->exc_value;
    tb = exc_state->exc_traceback;
    exc_state->exc_type = NULL;
    exc_state->exc_value = NULL;
    exc_state->exc_traceback = NULL;
    Py_XDECREF(t);
    Py_XDECREF(v);
    Py_XDECREF(tb);
}
#define __Pyx_Coroutine_AlreadyRunningError(gen)  (__Pyx__Coroutine_AlreadyRunningError(gen), (PyObject*)NULL)
static void __Pyx__Coroutine_AlreadyRunningError(CYTHON_UNUSED __pyx_CoroutineObject *gen) {
    const char *msg;
    if ((0)) {
    #ifdef __Pyx_Coroutine_USED
    } else if (__Pyx_Coroutine_Check((PyObject*)gen)) {
        msg = "coroutine already executing";
    #endif
    #ifdef __Pyx_AsyncGen_USED
    } else if (__Pyx_AsyncGen_CheckExact((PyObject*)gen)) {
        msg = "async generator already executing";
    #endif
    } else {
        msg = "generator already executing";
    }
    PyErr_SetString(PyExc_ValueError, msg);
}
#define __Pyx_Coroutine_NotStartedError(gen)  (__Pyx__Coroutine_NotStartedError(gen), (PyObject*)NULL)
static void __Pyx__Coroutine_NotStartedError(CYTHON_UNUSED PyObject *gen) {
    const char *msg;
    if ((0)) {
    #ifdef __Pyx_Coroutine_USED
    } else if (__Pyx_Coroutine_Check(gen)) {
        msg = "can't send non-None value to a just-started coroutine";
    #endif
    #ifdef __Pyx_AsyncGen_USED
    } else if (__Pyx_AsyncGen_CheckExact(gen)) {
        msg = "can't send non-None value to a just-started async generator";
    #endif
    } else {
        msg = "can't send non-None value to a just-started generator";
    }
    PyErr_SetString(PyExc_TypeError, msg);
}
#define __Pyx_Coroutine_AlreadyTerminatedError(gen, value, closing)  (__Pyx__Coroutine_AlreadyTerminatedError(gen, value, closing), (PyObject*)NULL)
static void __Pyx__Coroutine_AlreadyTerminatedError(CYTHON_UNUSED PyObject *gen, PyObject *value, CYTHON_UNUSED int closing) {
    #ifdef __Pyx_Coroutine_USED
    if (!closing && __Pyx_Coroutine_Check(gen)) {
        PyErr_SetString(PyExc_RuntimeError, "cannot reuse already awaited coroutine");
    } else
    #endif
    if (value) {
        #ifdef __Pyx_AsyncGen_USED
        if (__Pyx_AsyncGen_CheckExact(gen))
            PyErr_SetNone(__Pyx_PyExc_StopAsyncIteration);
        else
        #endif
        PyErr_SetNone(PyExc_StopIteration);
    }
}
static
PyObject *__Pyx_Coroutine_SendEx(__pyx_CoroutineObject *self, PyObject *value, int closing) {
    __Pyx_PyThreadState_declare
    PyThreadState *tstate;
    __Pyx_ExcInfoStruct *exc_state;
    PyObject *retval;
    assert(!self->is_running);
    if (unlikely(self->resume_label == 0)) {
        if (unlikely(value && value != Py_None)) {
            return __Pyx_Coroutine_NotStartedError((PyObject*)self);
        }
    }
    if (unlikely(self->resume_label == -1)) {
        return __Pyx_Coroutine_AlreadyTerminatedError((PyObject*)self, value, closing);
    }
#if CYTHON_FAST_THREAD_STATE
    __Pyx_PyThreadState_assign
    tstate = __pyx_tstate;
#else
    tstate = __Pyx_PyThreadState_Current;
#endif
    exc_state = &self->gi_exc_state;
    if (exc_state->exc_type) {
        #if CYTHON_COMPILING_IN_PYPY || CYTHON_COMPILING_IN_PYSTON
        #else
        if (exc_state->exc_traceback) {
            PyTracebackObject *tb = (PyTracebackObject *) exc_state->exc_traceback;
            PyFrameObject *f = tb->tb_frame;
            Py_XINCREF(tstate->frame);
            assert(f->f_back == NULL);
            f->f_back = tstate->frame;
        }
        #endif
    }
#if CYTHON_USE_EXC_INFO_STACK
    exc_state->previous_item = tstate->exc_info;
    tstate->exc_info = exc_state;
#else
    if (exc_state->exc_type) {
        __Pyx_ExceptionSwap(&exc_state->exc_type, &exc_state->exc_value, &exc_state->exc_traceback);
    } else {
        __Pyx_Coroutine_ExceptionClear(exc_state);
        __Pyx_ExceptionSave(&exc_state->exc_type, &exc_state->exc_value, &exc_state->exc_traceback);
    }
#endif
    self->is_running = 1;
    retval = self->body((PyObject *) self, tstate, value);
    self->is_running = 0;
#if CYTHON_USE_EXC_INFO_STACK
    exc_state = &self->gi_exc_state;
    tstate->exc_info = exc_state->previous_item;
    exc_state->previous_item = NULL;
    __Pyx_Coroutine_ResetFrameBackpointer(exc_state);
#endif
    return retval;
}
static CYTHON_INLINE void __Pyx_Coroutine_ResetFrameBackpointer(__Pyx_ExcInfoStruct *exc_state) {
    PyObject *exc_tb = exc_state->exc_traceback;
    if (likely(exc_tb)) {
#if CYTHON_COMPILING_IN_PYPY || CYTHON_COMPILING_IN_PYSTON
#else
        PyTracebackObject *tb = (PyTracebackObject *) exc_tb;
        PyFrameObject *f = tb->tb_frame;
        Py_CLEAR(f->f_back);
#endif
    }
}
static CYTHON_INLINE
PyObject *__Pyx_Coroutine_MethodReturn(CYTHON_UNUSED PyObject* gen, PyObject *retval) {
    if (unlikely(!retval)) {
        __Pyx_PyThreadState_declare
        __Pyx_PyThreadState_assign
        if (!__Pyx_PyErr_Occurred()) {
            PyObject *exc = PyExc_StopIteration;
            #ifdef __Pyx_AsyncGen_USED
            if (__Pyx_AsyncGen_CheckExact(gen))
                exc = __Pyx_PyExc_StopAsyncIteration;
            #endif
            __Pyx_PyErr_SetNone(exc);
        }
    }
    return retval;
}
static CYTHON_INLINE
PyObject *__Pyx_Coroutine_FinishDelegation(__pyx_CoroutineObject *gen) {
    PyObject *ret;
    PyObject *val = NULL;
    __Pyx_Coroutine_Undelegate(gen);
    __Pyx_PyGen__FetchStopIterationValue(__Pyx_PyThreadState_Current, &val);
    ret = __Pyx_Coroutine_SendEx(gen, val, 0);
    Py_XDECREF(val);
    return ret;
}
static PyObject *__Pyx_Coroutine_Send(PyObject *self, PyObject *value) {
    PyObject *retval;
    __pyx_CoroutineObject *gen = (__pyx_CoroutineObject*) self;
    PyObject *yf = gen->yieldfrom;
    if (unlikely(gen->is_running))
        return __Pyx_Coroutine_AlreadyRunningError(gen);
    if (yf) {
        PyObject *ret;
        gen->is_running = 1;
        #ifdef __Pyx_Generator_USED
        if (__Pyx_Generator_CheckExact(yf)) {
            ret = __Pyx_Coroutine_Send(yf, value);
        } else
        #endif
        #ifdef __Pyx_Coroutine_USED
        if (__Pyx_Coroutine_Check(yf)) {
            ret = __Pyx_Coroutine_Send(yf, value);
        } else
        #endif
        #ifdef __Pyx_AsyncGen_USED
        if (__pyx_PyAsyncGenASend_CheckExact(yf)) {
            ret = __Pyx_async_gen_asend_send(yf, value);
        } else
        #endif
        #if CYTHON_COMPILING_IN_CPYTHON && PY_VERSION_HEX >= 0x03030000 && (defined(__linux__) || PY_VERSION_HEX >= 0x030600B3)
        if (PyGen_CheckExact(yf)) {
            ret = _PyGen_Send((PyGenObject*)yf, value == Py_None ? NULL : value);
        } else
        #endif
        #if CYTHON_COMPILING_IN_CPYTHON && PY_VERSION_HEX >= 0x03050000 && defined(PyCoro_CheckExact) && (defined(__linux__) || PY_VERSION_HEX >= 0x030600B3)
        if (PyCoro_CheckExact(yf)) {
            ret = _PyGen_Send((PyGenObject*)yf, value == Py_None ? NULL : value);
        } else
        #endif
        {
            if (value == Py_None)
                ret = Py_TYPE(yf)->tp_iternext(yf);
            else
                ret = __Pyx_PyObject_CallMethod1(yf, __pyx_n_s_send, value);
        }
        gen->is_running = 0;
        if (likely(ret)) {
            return ret;
        }
        retval = __Pyx_Coroutine_FinishDelegation(gen);
    } else {
        retval = __Pyx_Coroutine_SendEx(gen, value, 0);
    }
    return __Pyx_Coroutine_MethodReturn(self, retval);
}
static int __Pyx_Coroutine_CloseIter(__pyx_CoroutineObject *gen, PyObject *yf) {
    PyObject *retval = NULL;
    int err = 0;
    #ifdef __Pyx_Generator_USED
    if (__Pyx_Generator_CheckExact(yf)) {
        retval = __Pyx_Coroutine_Close(yf);
        if (!retval)
            return -1;
    } else
    #endif
    #ifdef __Pyx_Coroutine_USED
    if (__Pyx_Coroutine_Check(yf)) {
        retval = __Pyx_Coroutine_Close(yf);
        if (!retval)
            return -1;
    } else
    if (__Pyx_CoroutineAwait_CheckExact(yf)) {
        retval = __Pyx_CoroutineAwait_Close((__pyx_CoroutineAwaitObject*)yf, NULL);
        if (!retval)
            return -1;
    } else
    #endif
    #ifdef __Pyx_AsyncGen_USED
    if (__pyx_PyAsyncGenASend_CheckExact(yf)) {
        retval = __Pyx_async_gen_asend_close(yf, NULL);
    } else
    if (__pyx_PyAsyncGenAThrow_CheckExact(yf)) {
        retval = __Pyx_async_gen_athrow_close(yf, NULL);
    } else
    #endif
    {
        PyObject *meth;
        gen->is_running = 1;
        meth = __Pyx_PyObject_GetAttrStr(yf, __pyx_n_s_close);
        if (unlikely(!meth)) {
            if (!PyErr_ExceptionMatches(PyExc_AttributeError)) {
                PyErr_WriteUnraisable(yf);
            }
            PyErr_Clear();
        } else {
            retval = PyObject_CallFunction(meth, NULL);
            Py_DECREF(meth);
            if (!retval)
                err = -1;
        }
        gen->is_running = 0;
    }
    Py_XDECREF(retval);
    return err;
}
static PyObject *__Pyx_Generator_Next(PyObject *self) {
    __pyx_CoroutineObject *gen = (__pyx_CoroutineObject*) self;
    PyObject *yf = gen->yieldfrom;
    if (unlikely(gen->is_running))
        return __Pyx_Coroutine_AlreadyRunningError(gen);
    if (yf) {
        PyObject *ret;
        gen->is_running = 1;
        #ifdef __Pyx_Generator_USED
        if (__Pyx_Generator_CheckExact(yf)) {
            ret = __Pyx_Generator_Next(yf);
        } else
        #endif
        #if CYTHON_COMPILING_IN_CPYTHON && PY_VERSION_HEX >= 0x03030000 && (defined(__linux__) || PY_VERSION_HEX >= 0x030600B3)
        if (PyGen_CheckExact(yf)) {
            ret = _PyGen_Send((PyGenObject*)yf, NULL);
        } else
        #endif
        #ifdef __Pyx_Coroutine_USED
        if (__Pyx_Coroutine_Check(yf)) {
            ret = __Pyx_Coroutine_Send(yf, Py_None);
        } else
        #endif
            ret = Py_TYPE(yf)->tp_iternext(yf);
        gen->is_running = 0;
        if (likely(ret)) {
            return ret;
        }
        return __Pyx_Coroutine_FinishDelegation(gen);
    }
    return __Pyx_Coroutine_SendEx(gen, Py_None, 0);
}
static PyObject *__Pyx_Coroutine_Close_Method(PyObject *self, CYTHON_UNUSED PyObject *arg) {
    return __Pyx_Coroutine_Close(self);
}
static PyObject *__Pyx_Coroutine_Close(PyObject *self) {
    __pyx_CoroutineObject *gen = (__pyx_CoroutineObject *) self;
    PyObject *retval, *raised_exception;
    PyObject *yf = gen->yieldfrom;
    int err = 0;
    if (unlikely(gen->is_running))
        return __Pyx_Coroutine_AlreadyRunningError(gen);
    if (yf) {
        Py_INCREF(yf);
        err = __Pyx_Coroutine_CloseIter(gen, yf);
        __Pyx_Coroutine_Undelegate(gen);
        Py_DECREF(yf);
    }
    if (err == 0)
        PyErr_SetNone(PyExc_GeneratorExit);
    retval = __Pyx_Coroutine_SendEx(gen, NULL, 1);
    if (unlikely(retval)) {
        const char *msg;
        Py_DECREF(retval);
        if ((0)) {
        #ifdef __Pyx_Coroutine_USED
        } else if (__Pyx_Coroutine_Check(self)) {
            msg = "coroutine ignored GeneratorExit";
        #endif
        #ifdef __Pyx_AsyncGen_USED
        } else if (__Pyx_AsyncGen_CheckExact(self)) {
#if PY_VERSION_HEX < 0x03060000
            msg = "async generator ignored GeneratorExit - might require Python 3.6+ finalisation (PEP 525)";
#else
            msg = "async generator ignored GeneratorExit";
#endif
        #endif
        } else {
            msg = "generator ignored GeneratorExit";
        }
        PyErr_SetString(PyExc_RuntimeError, msg);
        return NULL;
    }
    raised_exception = PyErr_Occurred();
    if (likely(!raised_exception || __Pyx_PyErr_GivenExceptionMatches2(raised_exception, PyExc_GeneratorExit, PyExc_StopIteration))) {
        if (raised_exception) PyErr_Clear();
        Py_INCREF(Py_None);
        return Py_None;
    }
    return NULL;
}
static PyObject *__Pyx__Coroutine_Throw(PyObject *self, PyObject *typ, PyObject *val, PyObject *tb,
                                        PyObject *args, int close_on_genexit) {
    __pyx_CoroutineObject *gen = (__pyx_CoroutineObject *) self;
    PyObject *yf = gen->yieldfrom;
    if (unlikely(gen->is_running))
        return __Pyx_Coroutine_AlreadyRunningError(gen);
    if (yf) {
        PyObject *ret;
        Py_INCREF(yf);
        if (__Pyx_PyErr_GivenExceptionMatches(typ, PyExc_GeneratorExit) && close_on_genexit) {
            int err = __Pyx_Coroutine_CloseIter(gen, yf);
            Py_DECREF(yf);
            __Pyx_Coroutine_Undelegate(gen);
            if (err < 0)
                return __Pyx_Coroutine_MethodReturn(self, __Pyx_Coroutine_SendEx(gen, NULL, 0));
            goto throw_here;
        }
        gen->is_running = 1;
        if (0
        #ifdef __Pyx_Generator_USED
            || __Pyx_Generator_CheckExact(yf)
        #endif
        #ifdef __Pyx_Coroutine_USED
            || __Pyx_Coroutine_Check(yf)
        #endif
            ) {
            ret = __Pyx__Coroutine_Throw(yf, typ, val, tb, args, close_on_genexit);
        #ifdef __Pyx_Coroutine_USED
        } else if (__Pyx_CoroutineAwait_CheckExact(yf)) {
            ret = __Pyx__Coroutine_Throw(((__pyx_CoroutineAwaitObject*)yf)->coroutine, typ, val, tb, args, close_on_genexit);
        #endif
        } else {
            PyObject *meth = __Pyx_PyObject_GetAttrStr(yf, __pyx_n_s_throw);
            if (unlikely(!meth)) {
                Py_DECREF(yf);
                if (!PyErr_ExceptionMatches(PyExc_AttributeError)) {
                    gen->is_running = 0;
                    return NULL;
                }
                PyErr_Clear();
                __Pyx_Coroutine_Undelegate(gen);
                gen->is_running = 0;
                goto throw_here;
            }
            if (likely(args)) {
                ret = PyObject_CallObject(meth, args);
            } else {
                ret = PyObject_CallFunctionObjArgs(meth, typ, val, tb, NULL);
            }
            Py_DECREF(meth);
        }
        gen->is_running = 0;
        Py_DECREF(yf);
        if (!ret) {
            ret = __Pyx_Coroutine_FinishDelegation(gen);
        }
        return __Pyx_Coroutine_MethodReturn(self, ret);
    }
throw_here:
    __Pyx_Raise(typ, val, tb, NULL);
    return __Pyx_Coroutine_MethodReturn(self, __Pyx_Coroutine_SendEx(gen, NULL, 0));
}
static PyObject *__Pyx_Coroutine_Throw(PyObject *self, PyObject *args) {
    PyObject *typ;
    PyObject *val = NULL;
    PyObject *tb = NULL;
    if (!PyArg_UnpackTuple(args, (char *)"throw", 1, 3, &typ, &val, &tb))
        return NULL;
    return __Pyx__Coroutine_Throw(self, typ, val, tb, args, 1);
}
static CYTHON_INLINE int __Pyx_Coroutine_traverse_excstate(__Pyx_ExcInfoStruct *exc_state, visitproc visit, void *arg) {
    Py_VISIT(exc_state->exc_type);
    Py_VISIT(exc_state->exc_value);
    Py_VISIT(exc_state->exc_traceback);
    return 0;
}
static int __Pyx_Coroutine_traverse(__pyx_CoroutineObject *gen, visitproc visit, void *arg) {
    Py_VISIT(gen->closure);
    Py_VISIT(gen->classobj);
    Py_VISIT(gen->yieldfrom);
    return __Pyx_Coroutine_traverse_excstate(&gen->gi_exc_state, visit, arg);
}
static int __Pyx_Coroutine_clear(PyObject *self) {
    __pyx_CoroutineObject *gen = (__pyx_CoroutineObject *) self;
    Py_CLEAR(gen->closure);
    Py_CLEAR(gen->classobj);
    Py_CLEAR(gen->yieldfrom);
    __Pyx_Coroutine_ExceptionClear(&gen->gi_exc_state);
#ifdef __Pyx_AsyncGen_USED
    if (__Pyx_AsyncGen_CheckExact(self)) {
        Py_CLEAR(((__pyx_PyAsyncGenObject*)gen)->ag_finalizer);
    }
#endif
    Py_CLEAR(gen->gi_code);
    Py_CLEAR(gen->gi_name);
    Py_CLEAR(gen->gi_qualname);
    Py_CLEAR(gen->gi_modulename);
    return 0;
}
static void __Pyx_Coroutine_dealloc(PyObject *self) {
    __pyx_CoroutineObject *gen = (__pyx_CoroutineObject *) self;
    PyObject_GC_UnTrack(gen);
    if (gen->gi_weakreflist != NULL)
        PyObject_ClearWeakRefs(self);
    if (gen->resume_label >= 0) {
        PyObject_GC_Track(self);
#if PY_VERSION_HEX >= 0x030400a1 && CYTHON_USE_TP_FINALIZE
        if (PyObject_CallFinalizerFromDealloc(self))
#else
        Py_TYPE(gen)->tp_del(self);
        if (self->ob_refcnt > 0)
#endif
        {
            return;
        }
        PyObject_GC_UnTrack(self);
    }
#ifdef __Pyx_AsyncGen_USED
    if (__Pyx_AsyncGen_CheckExact(self)) {
        /* We have to handle this case for asynchronous generators
           right here, because this code has to be between UNTRACK
           and GC_Del. */
        Py_CLEAR(((__pyx_PyAsyncGenObject*)self)->ag_finalizer);
    }
#endif
    __Pyx_Coroutine_clear(self);
    PyObject_GC_Del(gen);
}
static void __Pyx_Coroutine_del(PyObject *self) {
    PyObject *error_type, *error_value, *error_traceback;
    __pyx_CoroutineObject *gen = (__pyx_CoroutineObject *) self;
    __Pyx_PyThreadState_declare
    if (gen->resume_label < 0) {
        return;
    }
#if !CYTHON_USE_TP_FINALIZE
    assert(self->ob_refcnt == 0);
    self->ob_refcnt = 1;
#endif
    __Pyx_PyThreadState_assign
    __Pyx_ErrFetch(&error_type, &error_value, &error_traceback);
#ifdef __Pyx_AsyncGen_USED
    if (__Pyx_AsyncGen_CheckExact(self)) {
        __pyx_PyAsyncGenObject *agen = (__pyx_PyAsyncGenObject*)self;
        PyObject *finalizer = agen->ag_finalizer;
        if (finalizer && !agen->ag_closed) {
            PyObject *res = __Pyx_PyObject_CallOneArg(finalizer, self);
            if (unlikely(!res)) {
                PyErr_WriteUnraisable(self);
            } else {
                Py_DECREF(res);
            }
            __Pyx_ErrRestore(error_type, error_value, error_traceback);
            return;
        }
    }
#endif
    if (unlikely(gen->resume_label == 0 && !error_value)) {
#ifdef __Pyx_Coroutine_USED
#ifdef __Pyx_Generator_USED
    if (!__Pyx_Generator_CheckExact(self))
#endif
        {
        PyObject_GC_UnTrack(self);
#if PY_MAJOR_VERSION >= 3  || defined(PyErr_WarnFormat)
        if (unlikely(PyErr_WarnFormat(PyExc_RuntimeWarning, 1, "coroutine '%.50S' was never awaited", gen->gi_qualname) < 0))
            PyErr_WriteUnraisable(self);
#else
        {PyObject *msg;
        char *cmsg;
        #if CYTHON_COMPILING_IN_PYPY
        msg = NULL;
        cmsg = (char*) "coroutine was never awaited";
        #else
        char *cname;
        PyObject *qualname;
        qualname = gen->gi_qualname;
        cname = PyString_AS_STRING(qualname);
        msg = PyString_FromFormat("coroutine '%.50s' was never awaited", cname);
        if (unlikely(!msg)) {
            PyErr_Clear();
            cmsg = (char*) "coroutine was never awaited";
        } else {
            cmsg = PyString_AS_STRING(msg);
        }
        #endif
        if (unlikely(PyErr_WarnEx(PyExc_RuntimeWarning, cmsg, 1) < 0))
            PyErr_WriteUnraisable(self);
        Py_XDECREF(msg);}
#endif
        PyObject_GC_Track(self);
        }
#endif
    } else {
        PyObject *res = __Pyx_Coroutine_Close(self);
        if (unlikely(!res)) {
            if (PyErr_Occurred())
                PyErr_WriteUnraisable(self);
        } else {
            Py_DECREF(res);
        }
    }
    __Pyx_ErrRestore(error_type, error_value, error_traceback);
#if !CYTHON_USE_TP_FINALIZE
    assert(self->ob_refcnt > 0);
    if (--self->ob_refcnt == 0) {
        return;
    }
    {
        Py_ssize_t refcnt = self->ob_refcnt;
        _Py_NewReference(self);
        self->ob_refcnt = refcnt;
    }
#if CYTHON_COMPILING_IN_CPYTHON
    assert(PyType_IS_GC(self->ob_type) &&
           _Py_AS_GC(self)->gc.gc_refs != _PyGC_REFS_UNTRACKED);
    _Py_DEC_REFTOTAL;
#endif
#ifdef COUNT_ALLOCS
    --Py_TYPE(self)->tp_frees;
    --Py_TYPE(self)->tp_allocs;
#endif
#endif
}
static PyObject *
__Pyx_Coroutine_get_name(__pyx_CoroutineObject *self, CYTHON_UNUSED void *context)
{
    PyObject *name = self->gi_name;
    if (unlikely(!name)) name = Py_None;
    Py_INCREF(name);
    return name;
}
static int
__Pyx_Coroutine_set_name(__pyx_CoroutineObject *self, PyObject *value, CYTHON_UNUSED void *context)
{
    PyObject *tmp;
#if PY_MAJOR_VERSION >= 3
    if (unlikely(value == NULL || !PyUnicode_Check(value)))
#else
    if (unlikely(value == NULL || !PyString_Check(value)))
#endif
    {
        PyErr_SetString(PyExc_TypeError,
                        "__name__ must be set to a string object");
        return -1;
    }
    tmp = self->gi_name;
    Py_INCREF(value);
    self->gi_name = value;
    Py_XDECREF(tmp);
    return 0;
}
static PyObject *
__Pyx_Coroutine_get_qualname(__pyx_CoroutineObject *self, CYTHON_UNUSED void *context)
{
    PyObject *name = self->gi_qualname;
    if (unlikely(!name)) name = Py_None;
    Py_INCREF(name);
    return name;
}
static int
__Pyx_Coroutine_set_qualname(__pyx_CoroutineObject *self, PyObject *value, CYTHON_UNUSED void *context)
{
    PyObject *tmp;
#if PY_MAJOR_VERSION >= 3
    if (unlikely(value == NULL || !PyUnicode_Check(value)))
#else
    if (unlikely(value == NULL || !PyString_Check(value)))
#endif
    {
        PyErr_SetString(PyExc_TypeError,
                        "__qualname__ must be set to a string object");
        return -1;
    }
    tmp = self->gi_qualname;
    Py_INCREF(value);
    self->gi_qualname = value;
    Py_XDECREF(tmp);
    return 0;
}
static __pyx_CoroutineObject *__Pyx__Coroutine_New(
            PyTypeObject* type, __pyx_coroutine_body_t body, PyObject *code, PyObject *closure,
            PyObject *name, PyObject *qualname, PyObject *module_name) {
    __pyx_CoroutineObject *gen = PyObject_GC_New(__pyx_CoroutineObject, type);
    if (unlikely(!gen))
        return NULL;
    return __Pyx__Coroutine_NewInit(gen, body, code, closure, name, qualname, module_name);
}
static __pyx_CoroutineObject *__Pyx__Coroutine_NewInit(
            __pyx_CoroutineObject *gen, __pyx_coroutine_body_t body, PyObject *code, PyObject *closure,
            PyObject *name, PyObject *qualname, PyObject *module_name) {
    gen->body = body;
    gen->closure = closure;
    Py_XINCREF(closure);
    gen->is_running = 0;
    gen->resume_label = 0;
    gen->classobj = NULL;
    gen->yieldfrom = NULL;
    gen->gi_exc_state.exc_type = NULL;
    gen->gi_exc_state.exc_value = NULL;
    gen->gi_exc_state.exc_traceback = NULL;
#if CYTHON_USE_EXC_INFO_STACK
    gen->gi_exc_state.previous_item = NULL;
#endif
    gen->gi_weakreflist = NULL;
    Py_XINCREF(qualname);
    gen->gi_qualname = qualname;
    Py_XINCREF(name);
    gen->gi_name = name;
    Py_XINCREF(module_name);
    gen->gi_modulename = module_name;
    Py_XINCREF(code);
    gen->gi_code = code;
    PyObject_GC_Track(gen);
    return gen;
}

/* PatchModuleWithCoroutine */
  static PyObject* __Pyx_Coroutine_patch_module(PyObject* module, const char* py_code) {
#if defined(__Pyx_Generator_USED) || defined(__Pyx_Coroutine_USED)
    int result;
    PyObject *globals, *result_obj;
    globals = PyDict_New();  if (unlikely(!globals)) goto ignore;
    result = PyDict_SetItemString(globals, "_cython_coroutine_type",
    #ifdef __Pyx_Coroutine_USED
        (PyObject*)__pyx_CoroutineType);
    #else
        Py_None);
    #endif
    if (unlikely(result < 0)) goto ignore;
    result = PyDict_SetItemString(globals, "_cython_generator_type",
    #ifdef __Pyx_Generator_USED
        (PyObject*)__pyx_GeneratorType);
    #else
        Py_None);
    #endif
    if (unlikely(result < 0)) goto ignore;
    if (unlikely(PyDict_SetItemString(globals, "_module", module) < 0)) goto ignore;
    if (unlikely(PyDict_SetItemString(globals, "__builtins__", __pyx_b) < 0)) goto ignore;
    result_obj = PyRun_String(py_code, Py_file_input, globals, globals);
    if (unlikely(!result_obj)) goto ignore;
    Py_DECREF(result_obj);
    Py_DECREF(globals);
    return module;
ignore:
    Py_XDECREF(globals);
    PyErr_WriteUnraisable(module);
    if (unlikely(PyErr_WarnEx(PyExc_RuntimeWarning, "Cython module failed to patch module with custom type", 1) < 0)) {
        Py_DECREF(module);
        module = NULL;
    }
#else
    py_code++;
#endif
    return module;
}

/* PatchGeneratorABC */
  #ifndef CYTHON_REGISTER_ABCS
#define CYTHON_REGISTER_ABCS 1
#endif
#if defined(__Pyx_Generator_USED) || defined(__Pyx_Coroutine_USED)
static PyObject* __Pyx_patch_abc_module(PyObject *module);
static PyObject* __Pyx_patch_abc_module(PyObject *module) {
    module = __Pyx_Coroutine_patch_module(
        module, ""
"if _cython_generator_type is not None:\n"
"    try: Generator = _module.Generator\n"
"    except AttributeError: pass\n"
"    else: Generator.register(_cython_generator_type)\n"
"if _cython_coroutine_type is not None:\n"
"    try: Coroutine = _module.Coroutine\n"
"    except AttributeError: pass\n"
"    else: Coroutine.register(_cython_coroutine_type)\n"
    );
    return module;
}
#endif
static int __Pyx_patch_abc(void) {
#if defined(__Pyx_Generator_USED) || defined(__Pyx_Coroutine_USED)
    static int abc_patched = 0;
    if (CYTHON_REGISTER_ABCS && !abc_patched) {
        PyObject *module;
        module = PyImport_ImportModule((PY_MAJOR_VERSION >= 3) ? "collections.abc" : "collections");
        if (!module) {
            PyErr_WriteUnraisable(NULL);
            if (unlikely(PyErr_WarnEx(PyExc_RuntimeWarning,
                    ((PY_MAJOR_VERSION >= 3) ?
                        "Cython module failed to register with collections.abc module" :
                        "Cython module failed to register with collections module"), 1) < 0)) {
                return -1;
            }
        } else {
            module = __Pyx_patch_abc_module(module);
            abc_patched = 1;
            if (unlikely(!module))
                return -1;
            Py_DECREF(module);
        }
        module = PyImport_ImportModule("backports_abc");
        if (module) {
            module = __Pyx_patch_abc_module(module);
            Py_XDECREF(module);
        }
        if (!module) {
            PyErr_Clear();
        }
    }
#else
    if ((0)) __Pyx_Coroutine_patch_module(NULL, NULL);
#endif
    return 0;
}

/* Generator */
  static PyMethodDef __pyx_Generator_methods[] = {
    {"send", (PyCFunction) __Pyx_Coroutine_Send, METH_O,
     (char*) PyDoc_STR("send(arg) -> send 'arg' into generator,\nreturn next yielded value or raise StopIteration.")},
    {"throw", (PyCFunction) __Pyx_Coroutine_Throw, METH_VARARGS,
     (char*) PyDoc_STR("throw(typ[,val[,tb]]) -> raise exception in generator,\nreturn next yielded value or raise StopIteration.")},
    {"close", (PyCFunction) __Pyx_Coroutine_Close_Method, METH_NOARGS,
     (char*) PyDoc_STR("close() -> raise GeneratorExit inside generator.")},
    {0, 0, 0, 0}
};
static PyMemberDef __pyx_Generator_memberlist[] = {
    {(char *) "gi_running", T_BOOL, offsetof(__pyx_CoroutineObject, is_running), READONLY, NULL},
    {(char*) "gi_yieldfrom", T_OBJECT, offsetof(__pyx_CoroutineObject, yieldfrom), READONLY,
     (char*) PyDoc_STR("object being iterated by 'yield from', or None")},
    {(char*) "gi_code", T_OBJECT, offsetof(__pyx_CoroutineObject, gi_code), READONLY, NULL},
    {0, 0, 0, 0, 0}
};
static PyGetSetDef __pyx_Generator_getsets[] = {
    {(char *) "__name__", (getter)__Pyx_Coroutine_get_name, (setter)__Pyx_Coroutine_set_name,
     (char*) PyDoc_STR("name of the generator"), 0},
    {(char *) "__qualname__", (getter)__Pyx_Coroutine_get_qualname, (setter)__Pyx_Coroutine_set_qualname,
     (char*) PyDoc_STR("qualified name of the generator"), 0},
    {0, 0, 0, 0, 0}
};
static PyTypeObject __pyx_GeneratorType_type = {
    PyVarObject_HEAD_INIT(0, 0)
    "generator",
    sizeof(__pyx_CoroutineObject),
    0,
    (destructor) __Pyx_Coroutine_dealloc,
    0,
    0,
    0,
    0,
    0,
    0,
    0,
    0,
    0,
    0,
    0,
    0,
    0,
    0,
    Py_TPFLAGS_DEFAULT | Py_TPFLAGS_HAVE_GC | Py_TPFLAGS_HAVE_FINALIZE,
    0,
    (traverseproc) __Pyx_Coroutine_traverse,
    0,
    0,
    offsetof(__pyx_CoroutineObject, gi_weakreflist),
    0,
    (iternextfunc) __Pyx_Generator_Next,
    __pyx_Generator_methods,
    __pyx_Generator_memberlist,
    __pyx_Generator_getsets,
    0,
    0,
    0,
    0,
    0,
    0,
    0,
    0,
    0,
    0,
    0,
    0,
    0,
    0,
    0,
#if CYTHON_USE_TP_FINALIZE
    0,
#else
    __Pyx_Coroutine_del,
#endif
    0,
#if CYTHON_USE_TP_FINALIZE
    __Pyx_Coroutine_del,
#elif PY_VERSION_HEX >= 0x030400a1
    0,
#endif
#if PY_VERSION_HEX >= 0x030800b1
    0,
#endif
};
static int __pyx_Generator_init(void) {
    __pyx_GeneratorType_type.tp_getattro = __Pyx_PyObject_GenericGetAttrNoDict;
    __pyx_GeneratorType_type.tp_iter = PyObject_SelfIter;
    __pyx_GeneratorType = __Pyx_FetchCommonType(&__pyx_GeneratorType_type);
    if (unlikely(!__pyx_GeneratorType)) {
        return -1;
    }
    return 0;
}

/* TypeInfoCompare */
  static int
__pyx_typeinfo_cmp(__Pyx_TypeInfo *a, __Pyx_TypeInfo *b)
{
    int i;
    if (!a || !b)
        return 0;
    if (a == b)
        return 1;
    if (a->size != b->size || a->typegroup != b->typegroup ||
            a->is_unsigned != b->is_unsigned || a->ndim != b->ndim) {
        if (a->typegroup == 'H' || b->typegroup == 'H') {
            return a->size == b->size;
        } else {
            return 0;
        }
    }
    if (a->ndim) {
        for (i = 0; i < a->ndim; i++)
            if (a->arraysize[i] != b->arraysize[i])
                return 0;
    }
    if (a->typegroup == 'S') {
        if (a->flags != b->flags)
            return 0;
        if (a->fields || b->fields) {
            if (!(a->fields && b->fields))
                return 0;
            for (i = 0; a->fields[i].type && b->fields[i].type; i++) {
                __Pyx_StructField *field_a = a->fields + i;
                __Pyx_StructField *field_b = b->fields + i;
                if (field_a->offset != field_b->offset ||
                    !__pyx_typeinfo_cmp(field_a->type, field_b->type))
                    return 0;
            }
            return !a->fields[i].type && !b->fields[i].type;
        }
    }
    return 1;
}

/* MemviewSliceValidateAndInit */
  static int
__pyx_check_strides(Py_buffer *buf, int dim, int ndim, int spec)
{
    if (buf->shape[dim] <= 1)
        return 1;
    if (buf->strides) {
        if (spec & __Pyx_MEMVIEW_CONTIG) {
            if (spec & (__Pyx_MEMVIEW_PTR|__Pyx_MEMVIEW_FULL)) {
                if (buf->strides[dim] != sizeof(void *)) {
                    PyErr_Format(PyExc_ValueError,
                                 "Buffer is not indirectly contiguous "
                                 "in dimension %d.", dim);
                    goto fail;
                }
            } else if (buf->strides[dim] != buf->itemsize) {
                PyErr_SetString(PyExc_ValueError,
                                "Buffer and memoryview are not contiguous "
                                "in the same dimension.");
                goto fail;
            }
        }
        if (spec & __Pyx_MEMVIEW_FOLLOW) {
            Py_ssize_t stride = buf->strides[dim];
            if (stride < 0)
                stride = -stride;
            if (stride < buf->itemsize) {
                PyErr_SetString(PyExc_ValueError,
                                "Buffer and memoryview are not contiguous "
                                "in the same dimension.");
                goto fail;
            }
        }
    } else {
        if (spec & __Pyx_MEMVIEW_CONTIG && dim != ndim - 1) {
            PyErr_Format(PyExc_ValueError,
                         "C-contiguous buffer is not contiguous in "
                         "dimension %d", dim);
            goto fail;
        } else if (spec & (__Pyx_MEMVIEW_PTR)) {
            PyErr_Format(PyExc_ValueError,
                         "C-contiguous buffer is not indirect in "
                         "dimension %d", dim);
            goto fail;
        } else if (buf->suboffsets) {
            PyErr_SetString(PyExc_ValueError,
                            "Buffer exposes suboffsets but no strides");
            goto fail;
        }
    }
    return 1;
fail:
    return 0;
}
static int
__pyx_check_suboffsets(Py_buffer *buf, int dim, CYTHON_UNUSED int ndim, int spec)
{
    if (spec & __Pyx_MEMVIEW_DIRECT) {
        if (buf->suboffsets && buf->suboffsets[dim] >= 0) {
            PyErr_Format(PyExc_ValueError,
                         "Buffer not compatible with direct access "
                         "in dimension %d.", dim);
            goto fail;
        }
    }
    if (spec & __Pyx_MEMVIEW_PTR) {
        if (!buf->suboffsets || (buf->suboffsets[dim] < 0)) {
            PyErr_Format(PyExc_ValueError,
                         "Buffer is not indirectly accessible "
                         "in dimension %d.", dim);
            goto fail;
        }
    }
    return 1;
fail:
    return 0;
}
static int
__pyx_verify_contig(Py_buffer *buf, int ndim, int c_or_f_flag)
{
    int i;
    if (c_or_f_flag & __Pyx_IS_F_CONTIG) {
        Py_ssize_t stride = 1;
        for (i = 0; i < ndim; i++) {
            if (stride * buf->itemsize != buf->strides[i] &&
                    buf->shape[i] > 1)
            {
                PyErr_SetString(PyExc_ValueError,
                    "Buffer not fortran contiguous.");
                goto fail;
            }
            stride = stride * buf->shape[i];
        }
    } else if (c_or_f_flag & __Pyx_IS_C_CONTIG) {
        Py_ssize_t stride = 1;
        for (i = ndim - 1; i >- 1; i--) {
            if (stride * buf->itemsize != buf->strides[i] &&
                    buf->shape[i] > 1) {
                PyErr_SetString(PyExc_ValueError,
                    "Buffer not C contiguous.");
                goto fail;
            }
            stride = stride * buf->shape[i];
        }
    }
    return 1;
fail:
    return 0;
}
static int __Pyx_ValidateAndInit_memviewslice(
                int *axes_specs,
                int c_or_f_flag,
                int buf_flags,
                int ndim,
                __Pyx_TypeInfo *dtype,
                __Pyx_BufFmt_StackElem stack[],
                __Pyx_memviewslice *memviewslice,
                PyObject *original_obj)
{
    struct __pyx_memoryview_obj *memview, *new_memview;
    __Pyx_RefNannyDeclarations
    Py_buffer *buf;
    int i, spec = 0, retval = -1;
    __Pyx_BufFmt_Context ctx;
    int from_memoryview = __pyx_memoryview_check(original_obj);
    __Pyx_RefNannySetupContext("ValidateAndInit_memviewslice", 0);
    if (from_memoryview && __pyx_typeinfo_cmp(dtype, ((struct __pyx_memoryview_obj *)
                                                            original_obj)->typeinfo)) {
        memview = (struct __pyx_memoryview_obj *) original_obj;
        new_memview = NULL;
    } else {
        memview = (struct __pyx_memoryview_obj *) __pyx_memoryview_new(
                                            original_obj, buf_flags, 0, dtype);
        new_memview = memview;
        if (unlikely(!memview))
            goto fail;
    }
    buf = &memview->view;
    if (buf->ndim != ndim) {
        PyErr_Format(PyExc_ValueError,
                "Buffer has wrong number of dimensions (expected %d, got %d)",
                ndim, buf->ndim);
        goto fail;
    }
    if (new_memview) {
        __Pyx_BufFmt_Init(&ctx, stack, dtype);
        if (!__Pyx_BufFmt_CheckString(&ctx, buf->format)) goto fail;
    }
    if ((unsigned) buf->itemsize != dtype->size) {
        PyErr_Format(PyExc_ValueError,
                     "Item size of buffer (%" CYTHON_FORMAT_SSIZE_T "u byte%s) "
                     "does not match size of '%s' (%" CYTHON_FORMAT_SSIZE_T "u byte%s)",
                     buf->itemsize,
                     (buf->itemsize > 1) ? "s" : "",
                     dtype->name,
                     dtype->size,
                     (dtype->size > 1) ? "s" : "");
        goto fail;
    }
    for (i = 0; i < ndim; i++) {
        spec = axes_specs[i];
        if (!__pyx_check_strides(buf, i, ndim, spec))
            goto fail;
        if (!__pyx_check_suboffsets(buf, i, ndim, spec))
            goto fail;
    }
    if (buf->strides && !__pyx_verify_contig(buf, ndim, c_or_f_flag))
        goto fail;
    if (unlikely(__Pyx_init_memviewslice(memview, ndim, memviewslice,
                                         new_memview != NULL) == -1)) {
        goto fail;
    }
    retval = 0;
    goto no_fail;
fail:
    Py_XDECREF(new_memview);
    retval = -1;
no_fail:
    __Pyx_RefNannyFinishContext();
    return retval;
}

/* ObjectToMemviewSlice */
  static CYTHON_INLINE __Pyx_memviewslice __Pyx_PyObject_to_MemoryviewSlice_ds_nn___pyx_t_13_rnaseq_utils_float32(PyObject *obj, int writable_flag) {
    __Pyx_memviewslice result = { 0, 0, { 0 }, { 0 }, { 0 } };
    __Pyx_BufFmt_StackElem stack[1];
    int axes_specs[] = { (__Pyx_MEMVIEW_DIRECT | __Pyx_MEMVIEW_STRIDED) };
    int retcode;
    if (obj == Py_None) {
        result.memview = (struct __pyx_memoryview_obj *) Py_None;
        return result;
    }
    retcode = __Pyx_ValidateAndInit_memviewslice(axes_specs, 0,
                                                 PyBUF_RECORDS_RO | writable_flag, 1,
                                                 &__Pyx_TypeInfo_nn___pyx_t_13_rnaseq_utils_float32, stack,
                                                 &result, obj);
    if (unlikely(retcode == -1))
        goto __pyx_fail;
    return result;
__pyx_fail:
    result.memview = NULL;
    result.data = NULL;
    return result;
}

/* ObjectToMemviewSlice */
  static CYTHON_INLINE __Pyx_memviewslice __Pyx_PyObject_to_MemoryviewSlice_ds_float(PyObject *obj, int writable_flag) {
    __Pyx_memviewslice result = { 0, 0, { 0 }, { 0 }, { 0 } };
    __Pyx_BufFmt_StackElem stack[1];
    int axes_specs[] = { (__Pyx_MEMVIEW_DIRECT | __Pyx_MEMVIEW_STRIDED) };
    int retcode;
    if (obj == Py_None) {
        result.memview = (struct __pyx_memoryview_obj *) Py_None;
        return result;
    }
    retcode = __Pyx_ValidateAndInit_memviewslice(axes_specs, 0,
                                                 PyBUF_RECORDS_RO | writable_flag, 1,
                                                 &__Pyx_TypeInfo_float, stack,
                                                 &result, obj);
    if (unlikely(retcode == -1))
        goto __pyx_fail;
    return result;
__pyx_fail:
    result.memview = NULL;
    result.data = NULL;
    return result;
}

/* CheckBinaryVersion */
  static int __Pyx_check_binary_version(void) {
    char ctversion[4], rtversion[4];
    PyOS_snprintf(ctversion, 4, "%d.%d", PY_MAJOR_VERSION, PY_MINOR_VERSION);
    PyOS_snprintf(rtversion, 4, "%s", Py_GetVersion());
    if (ctversion[0] != rtversion[0] || ctversion[2] != rtversion[2]) {
        char message[200];
        PyOS_snprintf(message, sizeof(message),
                      "compiletime version %s of module '%.100s' "
                      "does not match runtime version %s",
                      ctversion, __Pyx_MODULE_NAME, rtversion);
        return PyErr_WarnEx(NULL, message, 1);
    }
    return 0;
}

/* InitStrings */
  static int __Pyx_InitStrings(__Pyx_StringTabEntry *t) {
    while (t->p) {
        #if PY_MAJOR_VERSION < 3
        if (t->is_unicode) {
            *t->p = PyUnicode_DecodeUTF8(t->s, t->n - 1, NULL);
        } else if (t->intern) {
            *t->p = PyString_InternFromString(t->s);
        } else {
            *t->p = PyString_FromStringAndSize(t->s, t->n - 1);
        }
        #else
        if (t->is_unicode | t->is_str) {
            if (t->intern) {
                *t->p = PyUnicode_InternFromString(t->s);
            } else if (t->encoding) {
                *t->p = PyUnicode_Decode(t->s, t->n - 1, t->encoding, NULL);
            } else {
                *t->p = PyUnicode_FromStringAndSize(t->s, t->n - 1);
            }
        } else {
            *t->p = PyBytes_FromStringAndSize(t->s, t->n - 1);
        }
        #endif
        if (!*t->p)
            return -1;
        if (PyObject_Hash(*t->p) == -1)
            return -1;
        ++t;
    }
    return 0;
}

static CYTHON_INLINE PyObject* __Pyx_PyUnicode_FromString(const char* c_str) {
    return __Pyx_PyUnicode_FromStringAndSize(c_str, (Py_ssize_t)strlen(c_str));
}
static CYTHON_INLINE const char* __Pyx_PyObject_AsString(PyObject* o) {
    Py_ssize_t ignore;
    return __Pyx_PyObject_AsStringAndSize(o, &ignore);
}
#if __PYX_DEFAULT_STRING_ENCODING_IS_ASCII || __PYX_DEFAULT_STRING_ENCODING_IS_DEFAULT
#if !CYTHON_PEP393_ENABLED
static const char* __Pyx_PyUnicode_AsStringAndSize(PyObject* o, Py_ssize_t *length) {
    char* defenc_c;
    PyObject* defenc = _PyUnicode_AsDefaultEncodedString(o, NULL);
    if (!defenc) return NULL;
    defenc_c = PyBytes_AS_STRING(defenc);
#if __PYX_DEFAULT_STRING_ENCODING_IS_ASCII
    {
        char* end = defenc_c + PyBytes_GET_SIZE(defenc);
        char* c;
        for (c = defenc_c; c < end; c++) {
            if ((unsigned char) (*c) >= 128) {
                PyUnicode_AsASCIIString(o);
                return NULL;
            }
        }
    }
#endif
    *length = PyBytes_GET_SIZE(defenc);
    return defenc_c;
}
#else
static CYTHON_INLINE const char* __Pyx_PyUnicode_AsStringAndSize(PyObject* o, Py_ssize_t *length) {
    if (unlikely(__Pyx_PyUnicode_READY(o) == -1)) return NULL;
#if __PYX_DEFAULT_STRING_ENCODING_IS_ASCII
    if (likely(PyUnicode_IS_ASCII(o))) {
        *length = PyUnicode_GET_LENGTH(o);
        return PyUnicode_AsUTF8(o);
    } else {
        PyUnicode_AsASCIIString(o);
        return NULL;
    }
#else
    return PyUnicode_AsUTF8AndSize(o, length);
#endif
}
#endif
#endif
static CYTHON_INLINE const char* __Pyx_PyObject_AsStringAndSize(PyObject* o, Py_ssize_t *length) {
#if __PYX_DEFAULT_STRING_ENCODING_IS_ASCII || __PYX_DEFAULT_STRING_ENCODING_IS_DEFAULT
    if (
#if PY_MAJOR_VERSION < 3 && __PYX_DEFAULT_STRING_ENCODING_IS_ASCII
            __Pyx_sys_getdefaultencoding_not_ascii &&
#endif
            PyUnicode_Check(o)) {
        return __Pyx_PyUnicode_AsStringAndSize(o, length);
    } else
#endif
#if (!CYTHON_COMPILING_IN_PYPY) || (defined(PyByteArray_AS_STRING) && defined(PyByteArray_GET_SIZE))
    if (PyByteArray_Check(o)) {
        *length = PyByteArray_GET_SIZE(o);
        return PyByteArray_AS_STRING(o);
    } else
#endif
    {
        char* result;
        int r = PyBytes_AsStringAndSize(o, &result, length);
        if (unlikely(r < 0)) {
            return NULL;
        } else {
            return result;
        }
    }
}
static CYTHON_INLINE int __Pyx_PyObject_IsTrue(PyObject* x) {
   int is_true = x == Py_True;
   if (is_true | (x == Py_False) | (x == Py_None)) return is_true;
   else return PyObject_IsTrue(x);
}
static CYTHON_INLINE int __Pyx_PyObject_IsTrueAndDecref(PyObject* x) {
    int retval;
    if (unlikely(!x)) return -1;
    retval = __Pyx_PyObject_IsTrue(x);
    Py_DECREF(x);
    return retval;
}
static PyObject* __Pyx_PyNumber_IntOrLongWrongResultType(PyObject* result, const char* type_name) {
#if PY_MAJOR_VERSION >= 3
    if (PyLong_Check(result)) {
        if (PyErr_WarnFormat(PyExc_DeprecationWarning, 1,
                "__int__ returned non-int (type %.200s).  "
                "The ability to return an instance of a strict subclass of int "
                "is deprecated, and may be removed in a future version of Python.",
                Py_TYPE(result)->tp_name)) {
            Py_DECREF(result);
            return NULL;
        }
        return result;
    }
#endif
    PyErr_Format(PyExc_TypeError,
                 "__%.4s__ returned non-%.4s (type %.200s)",
                 type_name, type_name, Py_TYPE(result)->tp_name);
    Py_DECREF(result);
    return NULL;
}
static CYTHON_INLINE PyObject* __Pyx_PyNumber_IntOrLong(PyObject* x) {
#if CYTHON_USE_TYPE_SLOTS
  PyNumberMethods *m;
#endif
  const char *name = NULL;
  PyObject *res = NULL;
#if PY_MAJOR_VERSION < 3
  if (likely(PyInt_Check(x) || PyLong_Check(x)))
#else
  if (likely(PyLong_Check(x)))
#endif
    return __Pyx_NewRef(x);
#if CYTHON_USE_TYPE_SLOTS
  m = Py_TYPE(x)->tp_as_number;
  #if PY_MAJOR_VERSION < 3
  if (m && m->nb_int) {
    name = "int";
    res = m->nb_int(x);
  }
  else if (m && m->nb_long) {
    name = "long";
    res = m->nb_long(x);
  }
  #else
  if (likely(m && m->nb_int)) {
    name = "int";
    res = m->nb_int(x);
  }
  #endif
#else
  if (!PyBytes_CheckExact(x) && !PyUnicode_CheckExact(x)) {
    res = PyNumber_Int(x);
  }
#endif
  if (likely(res)) {
#if PY_MAJOR_VERSION < 3
    if (unlikely(!PyInt_Check(res) && !PyLong_Check(res))) {
#else
    if (unlikely(!PyLong_CheckExact(res))) {
#endif
        return __Pyx_PyNumber_IntOrLongWrongResultType(res, name);
    }
  }
  else if (!PyErr_Occurred()) {
    PyErr_SetString(PyExc_TypeError,
                    "an integer is required");
  }
  return res;
}
static CYTHON_INLINE Py_ssize_t __Pyx_PyIndex_AsSsize_t(PyObject* b) {
  Py_ssize_t ival;
  PyObject *x;
#if PY_MAJOR_VERSION < 3
  if (likely(PyInt_CheckExact(b))) {
    if (sizeof(Py_ssize_t) >= sizeof(long))
        return PyInt_AS_LONG(b);
    else
        return PyInt_AsSsize_t(b);
  }
#endif
  if (likely(PyLong_CheckExact(b))) {
    #if CYTHON_USE_PYLONG_INTERNALS
    const digit* digits = ((PyLongObject*)b)->ob_digit;
    const Py_ssize_t size = Py_SIZE(b);
    if (likely(__Pyx_sst_abs(size) <= 1)) {
        ival = likely(size) ? digits[0] : 0;
        if (size == -1) ival = -ival;
        return ival;
    } else {
      switch (size) {
         case 2:
           if (8 * sizeof(Py_ssize_t) > 2 * PyLong_SHIFT) {
             return (Py_ssize_t) (((((size_t)digits[1]) << PyLong_SHIFT) | (size_t)digits[0]));
           }
           break;
         case -2:
           if (8 * sizeof(Py_ssize_t) > 2 * PyLong_SHIFT) {
             return -(Py_ssize_t) (((((size_t)digits[1]) << PyLong_SHIFT) | (size_t)digits[0]));
           }
           break;
         case 3:
           if (8 * sizeof(Py_ssize_t) > 3 * PyLong_SHIFT) {
             return (Py_ssize_t) (((((((size_t)digits[2]) << PyLong_SHIFT) | (size_t)digits[1]) << PyLong_SHIFT) | (size_t)digits[0]));
           }
           break;
         case -3:
           if (8 * sizeof(Py_ssize_t) > 3 * PyLong_SHIFT) {
             return -(Py_ssize_t) (((((((size_t)digits[2]) << PyLong_SHIFT) | (size_t)digits[1]) << PyLong_SHIFT) | (size_t)digits[0]));
           }
           break;
         case 4:
           if (8 * sizeof(Py_ssize_t) > 4 * PyLong_SHIFT) {
             return (Py_ssize_t) (((((((((size_t)digits[3]) << PyLong_SHIFT) | (size_t)digits[2]) << PyLong_SHIFT) | (size_t)digits[1]) << PyLong_SHIFT) | (size_t)digits[0]));
           }
           break;
         case -4:
           if (8 * sizeof(Py_ssize_t) > 4 * PyLong_SHIFT) {
             return -(Py_ssize_t) (((((((((size_t)digits[3]) << PyLong_SHIFT) | (size_t)digits[2]) << PyLong_SHIFT) | (size_t)digits[1]) << PyLong_SHIFT) | (size_t)digits[0]));
           }
           break;
      }
    }
    #endif
    return PyLong_AsSsize_t(b);
  }
  x = PyNumber_Index(b);
  if (!x) return -1;
  ival = PyInt_AsSsize_t(x);
  Py_DECREF(x);
  return ival;
}
static CYTHON_INLINE PyObject * __Pyx_PyBool_FromLong(long b) {
  return b ? __Pyx_NewRef(Py_True) : __Pyx_NewRef(Py_False);
}
static CYTHON_INLINE PyObject * __Pyx_PyInt_FromSize_t(size_t ival) {
    return PyInt_FromSize_t(ival);
}


#endif /* Py_PYTHON_H */
