Minimize solvent
 &cntrl

  lastist= 4000000,
  lastrst= 4000000,

  ntx    = 1,       irest  = 0,
  ntpr   = 10,

  ntb    = 1,
  cut    = 9.0,     nsnb   = 10,   

  imin   = 1,       
  maxcyc = 1000,   
  ncyc   = 5000,   
  ntmin  = 1,       dx0    = 0.1,

  dt     = 0.001,

  ntr=1,
  restraint_wt=500.0,
  restraintmask=' :1-%(lenres)i',
 &end
 &rst
  iat=0,
 &end

