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      <rdf:Description rdf:about="#_00000001">
        <dc:description dc:type="description">A parameter scan will produce a similar figure to figure 1 (Sigmoidal response model, bottom left) of the reference publication. Different response models can be implemented by changing the quantity &apos;MODEL_TYPE&apos; from 0 to 4 with 0=Inactive, 1=Linear, 2=Hyperbolic, 3=Sigmoidal, 4=U-Shaped.</dc:description>
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              <vcard:N>
                <vcard:Given>Peter</vcard:Given>
                <vcard:Family>Lockwood</vcard:Family>
              </vcard:N>
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            <rdf:li>
              <vcard:N>
                <vcard:Given>Wayne</vcard:Given>
                <vcard:Family>Ewy</vcard:Family>
              </vcard:N>
            </rdf:li>
            <rdf:li>
              <vcard:N>
                <vcard:Given>David</vcard:Given>
                <vcard:Family>Hermann</vcard:Family>
              </vcard:N>
            </rdf:li>
            <rdf:li>
              <vcard:N>
                <vcard:Given>Nick</vcard:Given>
                <vcard:Family>Holford</vcard:Family>
              </vcard:N>
            </rdf:li>
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        </dc:creator>
        <dcterms:references>
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            <rdf:li>
              <bibo:Article>
                <bibo:authorList>Peter Lockwood, Wayne Ewy, David Hermann &amp; Nick Holford</bibo:authorList>
                <dc:title>Application of clinical trial simulation to compare proof-of-concept study designs for drugs with a slow onset of effect; an example in Alzheimer&apos;s disease.</dc:title>
                <bibo:journal>Pharmaceutical research</bibo:journal>
                <bibo:volume>23</bibo:volume>
                <bibo:issue>9</bibo:issue>
                <bibo:pages>2050-2059</bibo:pages>
                <dc:date>2006</dc:date>
                <bibo:doi>10.1007/s11095-006-9048-8</bibo:doi>
              </bibo:Article>
            </rdf:li>
          </rdf:Bag>
        </dcterms:references>
        <dcterms:license>CC0</dcterms:license>
        <dcterms:mediator>BioSimulations</dcterms:mediator>
      </rdf:Description>
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      <algorithm kisaoID="KISAO:0000019"/>
    </uniformTimeCourse>
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