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        <h1>
          <h1>Minimal Model for Circadian Oscillations</h1>
        </h1>
        <table cellspacing="0" cellpadding="2" border="0">
          <thead>
            <tr>
              <th valign="middle" bgcolor="#eeeeee" align="left">Citation</th>
            </tr>
          </thead>
          <tbody>
            <tr>
              <td>Vilar JMG, Kueh HY, Barkai N, Leibler S,							 (2002)							. Mechanisms of noise resistance in genetic oscillators,							  PNAS, 99(9):5988-5992.            <a href="http://www.pnas.org/%20%20%20%20%20%20%20%20cgi/content/abstract/99/9/5988">http://www.pnas.org/cgi/content/abstract/							99/9/5988</a></td>
            </tr>
          </tbody>
        </table>
        <table cellspacing="0" cellpadding="2" border="0">
          <thead>
            <tr>
              <th valign="middle" bgcolor="#eeeeee" align="left">Description</th>
            </tr>
          </thead>
          <tbody>
            <tr>
              <td>A minimal model of genomically based oscillation,							 based on two mutually interacting genes,							 an activator and a repressor. Postive feedback is provided by the activator protein,							 which binds to the promotors of both the activator and the repressor genes. Negative feedback is provided by the repressor protein which binds to the activator protein.</td>
            </tr>
          </tbody>
        </table>
        <table cellspacing="0" cellpadding="2" border="0">
          <thead>
            <tr>
              <th valign="middle" bgcolor="#eeeeee" align="left">Rate constant      </th>
              <th valign="middle" bgcolor="#eeeeee" align="left">Reaction</th>
            </tr>
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          <tbody>
            <tr>
              <td>alphaA = 50</td>
              <td>DA -&gt; DA + MA</td>
            </tr>
            <tr>
              <td>alphaAp = 500</td>
              <td>DAp -&gt; DAp + MA</td>
            </tr>
            <tr>
              <td>alphaR = 0.01</td>
              <td>DR -&gt; DR + MR</td>
            </tr>
            <tr>
              <td>alphaRp = 50</td>
              <td>DRp -&gt; DRp + MR</td>
            </tr>
            <tr>
              <td>betaA = 50</td>
              <td>MA -&gt; A + MA</td>
            </tr>
            <tr>
              <td>betaR = 5</td>
              <td>MR -&gt; MR + R</td>
            </tr>
            <tr>
              <td>gammaA = 1</td>
              <td>A + DA -&gt; DAp</td>
            </tr>
            <tr>
              <td>gammaC = 2</td>
              <td>A + R -&gt; C</td>
            </tr>
            <tr>
              <td>gammaR = 1</td>
              <td>A + DR -&gt; DRp</td>
            </tr>
            <tr>
              <td>deltaA = 1</td>
              <td>A -&gt; EmptySet</td>
            </tr>
            <tr>
              <td>deltaA = 1</td>
              <td>C -&gt; R</td>
            </tr>
            <tr>
              <td>deltaMA = 10</td>
              <td>MA -&gt; EmptySet</td>
            </tr>
            <tr>
              <td>deltaMR = 0.5</td>
              <td>MR -&gt; EmptySet</td>
            </tr>
            <tr>
              <td>deltaR = 0.2</td>
              <td>R -&gt; EmptySet</td>
            </tr>
            <tr>
              <td>thetaA = 50</td>
              <td>DAp -&gt; A + DA</td>
            </tr>
            <tr>
              <td>thetaR = 100</td>
              <td>DRp -&gt; A + DR</td>
            </tr>
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        <table cellspacing="0" cellpadding="2" border="0">
          <thead>
            <tr>
              <th valign="middle" bgcolor="#eeeeee" align="left">Variable</th>
              <th valign="middle" bgcolor="#eeeeee" align="left">IC  </th>
              <th valign="middle" bgcolor="#eeeeee" align="left">ODE</th>
            </tr>
          </thead>
          <tbody>
            <tr>
              <td>A</td>
              <td>0</td>
              <td>A&apos;[t] == -(deltaA*A[t]) - gammaA*A[t]*DA[t] + thetaA*DAp[							t] - gammaR*A[t]*DR[t] + thetaR*DRp[t] + betaA*MA[t] -							 gammaC*A[t]*R[t]</td>
            </tr>
            <tr>
              <td>C</td>
              <td>0</td>
              <td>C&apos;[t] == -(deltaA*C[t]) + gammaC*A[t]*R[t]</td>
            </tr>
            <tr>
              <td>DA</td>
              <td>1</td>
              <td>DA&apos;[t] == -(gammaA*A[t]*DA[t]) + thetaA*DAp[t]</td>
            </tr>
            <tr>
              <td>DAp</td>
              <td>0</td>
              <td>DAp&apos;[t] == gammaA*A[t]*DA[t] - thetaA*DAp[t]</td>
            </tr>
            <tr>
              <td>DR</td>
              <td>1</td>
              <td>DR&apos;[t] == -(gammaR*A[t]*DR[t]) + thetaR*DRp[t]</td>
            </tr>
            <tr>
              <td>DRp</td>
              <td>0</td>
              <td>DRp&apos;[t] == gammaR*A[t]*DR[t] - thetaR*DRp[t]</td>
            </tr>
            <tr>
              <td>MA</td>
              <td>0</td>
              <td>MA&apos;[t] == alphaA*DA[t] + alphaAp*DAp[t] - deltaMA*MA[t]</td>
            </tr>
            <tr>
              <td>MR</td>
              <td>0</td>
              <td>MR&apos;[t] == alphaR*DR[t] + alphaRp*DRp[t] - deltaMR*MR[t]</td>
            </tr>
            <tr>
              <td>R</td>
              <td>0</td>
              <td>R&apos;[t] == deltaA*C[t] + betaR*MR[t] - deltaR*R[t] -							 gammaC*A[t]*R[t]</td>
            </tr>
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        <p>Generated by Cellerator Version 1.0 update 2.1127 using Mathematica 4.2 for 				Mac OS X (June 4, 2002), November 27, 2002 12:17:46, using (PowerMac,PowerPC,				Mac OS X,MacOSX,Darwin)</p>
        <p>author=B.E.Shapiro</p>
        <p>This model originates from BioModels Database: A Database of Annotated Published Models. It is copyright (c) 2005-2009 The BioModels Team.      <br/>          For more information see the      <a href="http://www.ebi.ac.uk/biomodels/legal.html" target="_blank">terms of use</a>          .      <br/>          To cite BioModels Database, please use      <a href="http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&amp;pubmedid=16381960" target="_blank">Le Novère N., Bornstein B., Broicher A., Courtot M., Donizelli M., Dharuri H., Li L., Sauro H., Schilstra M., Shapiro B., Snoep J.L., Hucka M. (2006) BioModels Database: A Free, Centralized Database of Curated, Published, Quantitative Kinetic Models of Biochemical and Cellular Systems Nucleic Acids Res., 34: D689-D691.</a></p>
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            </rdf:RDF>
          </COPASI>
        </annotation>
      </species>
      <species metaid="COPASI6" id="DAp" name="DAp" compartment="deterministicOscillator" initialConcentration="0" boundaryCondition="false" constant="false">
        <annotation>
          <COPASI xmlns="http://www.copasi.org/static/sbml">
            <rdf:RDF xmlns:dcterms="http://purl.org/dc/terms/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
              <rdf:Description rdf:about="#COPASI6">
                <dcterms:created>
                  <rdf:Description>
                    <dcterms:W3CDTF>2019-10-22T15:45:58Z</dcterms:W3CDTF>
                  </rdf:Description>
                </dcterms:created>
              </rdf:Description>
            </rdf:RDF>
          </COPASI>
        </annotation>
      </species>
      <species metaid="COPASI7" id="DR" name="DR" compartment="deterministicOscillator" initialConcentration="1" boundaryCondition="false" constant="false">
        <annotation>
          <COPASI xmlns="http://www.copasi.org/static/sbml">
            <rdf:RDF xmlns:dcterms="http://purl.org/dc/terms/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
              <rdf:Description rdf:about="#COPASI7">
                <dcterms:created>
                  <rdf:Description>
                    <dcterms:W3CDTF>2019-10-22T15:45:58Z</dcterms:W3CDTF>
                  </rdf:Description>
                </dcterms:created>
              </rdf:Description>
            </rdf:RDF>
          </COPASI>
        </annotation>
      </species>
      <species metaid="COPASI8" id="DRp" name="DRp" compartment="deterministicOscillator" initialConcentration="0" boundaryCondition="false" constant="false">
        <annotation>
          <COPASI xmlns="http://www.copasi.org/static/sbml">
            <rdf:RDF xmlns:dcterms="http://purl.org/dc/terms/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
              <rdf:Description rdf:about="#COPASI8">
                <dcterms:created>
                  <rdf:Description>
                    <dcterms:W3CDTF>2019-10-22T15:45:58Z</dcterms:W3CDTF>
                  </rdf:Description>
                </dcterms:created>
              </rdf:Description>
            </rdf:RDF>
          </COPASI>
        </annotation>
      </species>
      <species metaid="COPASI9" id="MA" name="MA" compartment="deterministicOscillator" initialConcentration="0" boundaryCondition="false" constant="false">
        <annotation>
          <COPASI xmlns="http://www.copasi.org/static/sbml">
            <rdf:RDF xmlns:CopasiMT="http://www.copasi.org/RDF/MiriamTerms#" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
              <rdf:Description rdf:about="#COPASI9">
                <CopasiMT:isVersionOf>
                  <rdf:Bag>
                    <rdf:li rdf:resource="http://identifiers.org/chebi/CHEBI:33699"/>
                  </rdf:Bag>
                </CopasiMT:isVersionOf>
              </rdf:Description>
            </rdf:RDF>
          </COPASI>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#COPASI9">
              <bqbiol:isVersionOf>
                <rdf:Bag>
                  <rdf:li rdf:resource="http://identifiers.org/chebi/CHEBI:33699"/>
                </rdf:Bag>
              </bqbiol:isVersionOf>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
      </species>
      <species metaid="COPASI10" id="MR" name="MR" compartment="deterministicOscillator" initialConcentration="0" boundaryCondition="false" constant="false">
        <annotation>
          <COPASI xmlns="http://www.copasi.org/static/sbml">
            <rdf:RDF xmlns:CopasiMT="http://www.copasi.org/RDF/MiriamTerms#" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
              <rdf:Description rdf:about="#COPASI10">
                <CopasiMT:isVersionOf>
                  <rdf:Bag>
                    <rdf:li rdf:resource="http://identifiers.org/chebi/CHEBI:33699"/>
                  </rdf:Bag>
                </CopasiMT:isVersionOf>
              </rdf:Description>
            </rdf:RDF>
          </COPASI>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#COPASI10">
              <bqbiol:isVersionOf>
                <rdf:Bag>
                  <rdf:li rdf:resource="http://identifiers.org/chebi/CHEBI:33699"/>
                </rdf:Bag>
              </bqbiol:isVersionOf>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
      </species>
      <species metaid="COPASI11" id="R" name="R" compartment="deterministicOscillator" initialConcentration="0" boundaryCondition="false" constant="false">
        <annotation>
          <COPASI xmlns="http://www.copasi.org/static/sbml">
            <rdf:RDF xmlns:CopasiMT="http://www.copasi.org/RDF/MiriamTerms#" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
              <rdf:Description rdf:about="#COPASI11">
                <CopasiMT:isVersionOf>
                  <rdf:Bag>
                    <rdf:li rdf:resource="http://identifiers.org/chebi/CHEBI:36080"/>
                  </rdf:Bag>
                </CopasiMT:isVersionOf>
              </rdf:Description>
            </rdf:RDF>
          </COPASI>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#COPASI11">
              <bqbiol:isVersionOf>
                <rdf:Bag>
                  <rdf:li rdf:resource="http://identifiers.org/chebi/CHEBI:36080"/>
                </rdf:Bag>
              </bqbiol:isVersionOf>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
      </species>
    </listOfSpecies>
    <listOfReactions>
      <reaction metaid="COPASI12" id="Reaction1" name="Reaction1" reversible="false">
        <annotation>
          <COPASI xmlns="http://www.copasi.org/static/sbml">
            <rdf:RDF xmlns:CopasiMT="http://www.copasi.org/RDF/MiriamTerms#" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
              <rdf:Description rdf:about="#COPASI12">
                <CopasiMT:isVersionOf>
                  <rdf:Bag>
                    <rdf:li rdf:resource="http://identifiers.org/obo.go/GO:0006461"/>
                  </rdf:Bag>
                </CopasiMT:isVersionOf>
              </rdf:Description>
            </rdf:RDF>
          </COPASI>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#COPASI12">
              <bqbiol:isVersionOf>
                <rdf:Bag>
                  <rdf:li rdf:resource="http://identifiers.org/go/GO:0006461"/>
                </rdf:Bag>
              </bqbiol:isVersionOf>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="A" stoichiometry="1"/>
          <speciesReference species="R" stoichiometry="1"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="C" stoichiometry="1"/>
        </listOfProducts>
        <kineticLaw>
          <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
              <times/>
              <ci> deterministicOscillator </ci>
              <apply>
                <ci> Function_for_Reaction1_1 </ci>
                <ci> A </ci>
                <ci> R </ci>
                <ci> deterministicOscillator </ci>
                <ci> gammaC </ci>
              </apply>
            </apply>
          </math>
          <listOfParameters>
            <parameter id="gammaC" name="gammaC" value="2"/>
          </listOfParameters>
        </kineticLaw>
      </reaction>
      <reaction metaid="COPASI13" id="Reaction2" name="Reaction2" reversible="false">
        <annotation>
          <COPASI xmlns="http://www.copasi.org/static/sbml">
            <rdf:RDF xmlns:CopasiMT="http://www.copasi.org/RDF/MiriamTerms#" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
              <rdf:Description rdf:about="#COPASI13">
                <CopasiMT:isVersionOf>
                  <rdf:Bag>
                    <rdf:li rdf:resource="http://identifiers.org/obo.go/GO:0030163"/>
                  </rdf:Bag>
                </CopasiMT:isVersionOf>
              </rdf:Description>
            </rdf:RDF>
          </COPASI>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#COPASI13">
              <bqbiol:isVersionOf>
                <rdf:Bag>
                  <rdf:li rdf:resource="http://identifiers.org/go/GO:0030163"/>
                </rdf:Bag>
              </bqbiol:isVersionOf>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="A" stoichiometry="1"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="EmptySet" stoichiometry="1"/>
        </listOfProducts>
        <kineticLaw>
          <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
              <times/>
              <ci> deterministicOscillator </ci>
              <ci> k1 </ci>
              <ci> A </ci>
            </apply>
          </math>
          <listOfParameters>
            <parameter id="k1" name="k1" value="1"/>
          </listOfParameters>
        </kineticLaw>
      </reaction>
      <reaction metaid="COPASI14" id="Reaction3" name="Reaction3" reversible="false">
        <annotation>
          <COPASI xmlns="http://www.copasi.org/static/sbml">
            <rdf:RDF xmlns:CopasiMT="http://www.copasi.org/RDF/MiriamTerms#" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
              <rdf:Description rdf:about="#COPASI14">
                <CopasiMT:isVersionOf>
                  <rdf:Bag>
                    <rdf:li rdf:resource="http://identifiers.org/obo.go/GO:0030163"/>
                  </rdf:Bag>
                </CopasiMT:isVersionOf>
              </rdf:Description>
            </rdf:RDF>
          </COPASI>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#COPASI14">
              <bqbiol:isVersionOf>
                <rdf:Bag>
                  <rdf:li rdf:resource="http://identifiers.org/go/GO:0030163"/>
                </rdf:Bag>
              </bqbiol:isVersionOf>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="C" stoichiometry="1"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="R" stoichiometry="1"/>
        </listOfProducts>
        <kineticLaw>
          <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
              <times/>
              <ci> deterministicOscillator </ci>
              <ci> k1 </ci>
              <ci> C </ci>
            </apply>
          </math>
          <listOfParameters>
            <parameter id="k1" name="k1" value="1"/>
          </listOfParameters>
        </kineticLaw>
      </reaction>
      <reaction metaid="COPASI15" id="Reaction4" name="Reaction4" reversible="false">
        <annotation>
          <COPASI xmlns="http://www.copasi.org/static/sbml">
            <rdf:RDF xmlns:CopasiMT="http://www.copasi.org/RDF/MiriamTerms#" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
              <rdf:Description rdf:about="#COPASI15">
                <CopasiMT:isVersionOf>
                  <rdf:Bag>
                    <rdf:li rdf:resource="http://identifiers.org/obo.go/GO:0030163"/>
                  </rdf:Bag>
                </CopasiMT:isVersionOf>
              </rdf:Description>
            </rdf:RDF>
          </COPASI>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#COPASI15">
              <bqbiol:isVersionOf>
                <rdf:Bag>
                  <rdf:li rdf:resource="http://identifiers.org/go/GO:0030163"/>
                </rdf:Bag>
              </bqbiol:isVersionOf>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="R" stoichiometry="1"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="EmptySet" stoichiometry="1"/>
        </listOfProducts>
        <kineticLaw>
          <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
              <times/>
              <ci> deterministicOscillator </ci>
              <ci> k1 </ci>
              <ci> R </ci>
            </apply>
          </math>
          <listOfParameters>
            <parameter id="k1" name="k1" value="0.2"/>
          </listOfParameters>
        </kineticLaw>
      </reaction>
      <reaction metaid="COPASI16" id="Reaction5" name="Reaction5" reversible="false">
        <annotation>
          <COPASI xmlns="http://www.copasi.org/static/sbml">
            <rdf:RDF xmlns:CopasiMT="http://www.copasi.org/RDF/MiriamTerms#" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
              <rdf:Description rdf:about="#COPASI16">
                <CopasiMT:isVersionOf>
                  <rdf:Bag>
                    <rdf:li rdf:resource="http://identifiers.org/obo.go/GO:0016563"/>
                  </rdf:Bag>
                </CopasiMT:isVersionOf>
              </rdf:Description>
            </rdf:RDF>
          </COPASI>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#COPASI16">
              <bqbiol:isVersionOf>
                <rdf:Bag>
                  <rdf:li rdf:resource="http://identifiers.org/go/GO:0016563"/>
                </rdf:Bag>
              </bqbiol:isVersionOf>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="A" stoichiometry="1"/>
          <speciesReference species="DA" stoichiometry="1"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="DAp" stoichiometry="1"/>
        </listOfProducts>
        <kineticLaw>
          <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
              <times/>
              <ci> deterministicOscillator </ci>
              <apply>
                <ci> Function_for_Reaction5_1 </ci>
                <ci> A </ci>
                <ci> DA </ci>
                <ci> deterministicOscillator </ci>
                <ci> gammaA </ci>
              </apply>
            </apply>
          </math>
          <listOfParameters>
            <parameter id="gammaA" name="gammaA" value="1"/>
          </listOfParameters>
        </kineticLaw>
      </reaction>
      <reaction metaid="COPASI17" id="Reaction6" name="Reaction6" reversible="false">
        <annotation>
          <COPASI xmlns="http://www.copasi.org/static/sbml">
            <rdf:RDF xmlns:CopasiMT="http://www.copasi.org/RDF/MiriamTerms#" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
              <rdf:Description rdf:about="#COPASI17">
                <CopasiMT:isVersionOf>
                  <rdf:Bag>
                    <rdf:li rdf:resource="http://identifiers.org/obo.go/GO:0032986"/>
                  </rdf:Bag>
                </CopasiMT:isVersionOf>
              </rdf:Description>
            </rdf:RDF>
          </COPASI>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#COPASI17">
              <bqbiol:isVersionOf>
                <rdf:Bag>
                  <rdf:li rdf:resource="http://identifiers.org/go/GO:0032986"/>
                </rdf:Bag>
              </bqbiol:isVersionOf>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="DAp" stoichiometry="1"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="A" stoichiometry="1"/>
          <speciesReference species="DA" stoichiometry="1"/>
        </listOfProducts>
        <kineticLaw>
          <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
              <times/>
              <ci> deterministicOscillator </ci>
              <ci> k1 </ci>
              <ci> DAp </ci>
            </apply>
          </math>
          <listOfParameters>
            <parameter id="k1" name="k1" value="50"/>
          </listOfParameters>
        </kineticLaw>
      </reaction>
      <reaction metaid="COPASI18" id="Reaction7" name="Reaction7" reversible="false">
        <annotation>
          <COPASI xmlns="http://www.copasi.org/static/sbml">
            <rdf:RDF xmlns:CopasiMT="http://www.copasi.org/RDF/MiriamTerms#" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
              <rdf:Description rdf:about="#COPASI18">
                <CopasiMT:isVersionOf>
                  <rdf:Bag>
                    <rdf:li rdf:resource="http://identifiers.org/obo.go/GO:0006351"/>
                  </rdf:Bag>
                </CopasiMT:isVersionOf>
              </rdf:Description>
            </rdf:RDF>
          </COPASI>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#COPASI18">
              <bqbiol:isVersionOf>
                <rdf:Bag>
                  <rdf:li rdf:resource="http://identifiers.org/go/GO:0006351"/>
                </rdf:Bag>
              </bqbiol:isVersionOf>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="DA" stoichiometry="1"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="DA" stoichiometry="1"/>
          <speciesReference species="MA" stoichiometry="1"/>
        </listOfProducts>
        <kineticLaw>
          <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
              <times/>
              <ci> deterministicOscillator </ci>
              <ci> k1 </ci>
              <ci> DA </ci>
            </apply>
          </math>
          <listOfParameters>
            <parameter id="k1" name="k1" value="50"/>
          </listOfParameters>
        </kineticLaw>
      </reaction>
      <reaction metaid="COPASI19" id="Reaction8" name="Reaction8" reversible="false">
        <annotation>
          <COPASI xmlns="http://www.copasi.org/static/sbml">
            <rdf:RDF xmlns:CopasiMT="http://www.copasi.org/RDF/MiriamTerms#" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
              <rdf:Description rdf:about="#COPASI19">
                <CopasiMT:isVersionOf>
                  <rdf:Bag>
                    <rdf:li rdf:resource="http://identifiers.org/obo.go/GO:0006351"/>
                  </rdf:Bag>
                </CopasiMT:isVersionOf>
              </rdf:Description>
            </rdf:RDF>
          </COPASI>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#COPASI19">
              <bqbiol:isVersionOf>
                <rdf:Bag>
                  <rdf:li rdf:resource="http://identifiers.org/go/GO:0006351"/>
                </rdf:Bag>
              </bqbiol:isVersionOf>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="DAp" stoichiometry="1"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="DAp" stoichiometry="1"/>
          <speciesReference species="MA" stoichiometry="1"/>
        </listOfProducts>
        <kineticLaw>
          <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
              <times/>
              <ci> deterministicOscillator </ci>
              <ci> k1 </ci>
              <ci> DAp </ci>
            </apply>
          </math>
          <listOfParameters>
            <parameter id="k1" name="k1" value="500"/>
          </listOfParameters>
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